TTYH1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TTYH1
Entrez Gene ID	57348
Full Name	tweety family member 1
General protein information	Preferred Names tweety family member 1 Names protein tweety homolog 1 hTTY1 tweety homolog 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19q13.42
Summary	This gene encodes a member of the tweety family of proteins. Members of this family function as chloride anion channels. The encoded protein functions as a calcium(2+)-independent, volume-sensitive large conductance chloride(-) channel. Three transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jan 2011].
Disorder MIM:	605784

mRNA and Protein(s)

mRNA	Protein	Name
XM_017027025.1	XP_016882514.1	protein tweety homolog 1 isoform X1
NM_020659.4	NP_065710.1	protein tweety homolog 1 isoform 1
NM_001201461.1	NP_001188390.1	protein tweety homolog 1 isoform 3
NM_020659.3	NP_065710.1	protein tweety homolog 1 isoform 1
NM_001201461.2	NP_001188390.1	protein tweety homolog 1 isoform 3
NM_001005367.2	NP_001005367.1	protein tweety homolog 1 isoform 2
XM_017027026.1	XP_016882515.1	protein tweety homolog 1 isoform X2
NM_001005367.3	NP_001005367.1	protein tweety homolog 1 isoform 2

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Ttyh1	NP_001099695.1
Xenopus tropicalis (tropical clawed frog)	ttyh1	NP_001072899.1
Mus musculus (house mouse)	Ttyh1	NP_067299.2
Danio rerio (zebrafish)	LOC100537642	XP_003200200.2
Bos taurus (cattle)	TTYH1	NP_001070483.1
Homo sapiens (human)	TTYH1	NP_001188390.1
Pan troglodytes (chimpanzee)	TTYH1	XP_512893.3
Canis lupus familiaris (dog)	TTYH1	XP_862607.1

Gene Ontology
Bibliography

Related articles in PubMed

Tweety-Homolog 1 Drives Brain Colonization of Gliomas.
Jung E, Osswald M, Blaes J, Wiestler B, Sahm F, Schmenger T, Solecki G, Deumelandt K, Kurz FT, Xie R, Weil S, Heil O, Thom? C, G?mmel M, Syed M, H?ring P, Huber PE, Heiland S, Platten M, von Deimling A, Wick W, Winkler F
The Journal of neuroscience : the official journal of the Society for Neuroscience37(29)6837-6850(2017 Jul)

Systematic protein-protein interaction mapping for clinically relevant human GPCRs.
Sokolina K, Kittanakom S, Snider J, Kotlyar M, Maurice P, Gand?a J, Benleulmi-Chaachoua A, Tadagaki K, Oishi A, Wong V, Malty RH, Deineko V, Aoki H, Amin S, Yao Z, Morat? X, Otasek D, Kobayashi H, Menendez J, Auerbach D, Angers S, Pr?ulj N, Bouvier M, Babu M, Ciruela F, Jockers R, Jurisica I, Stagljar I
Molecular systems biology13(3)918(2017 03)

Validation of analytical breast cancer microarray analysis in medical laboratory.
Darweesh AS, Louka ML, Hana M, Rashad S, El-Shinawi M, Sharaf-Eldin A, Kassim SK
Medical oncology (Northwood, London, England)31(10)201(2014 Oct)

Fusion of TTYH1 with the C19MC microRNA cluster drives expression of a brain-specific DNMT3B isoform in the embryonal brain tumor ETMR.
Kleinman CL, Gerges N, Papillon-Cavanagh S, Sin-Chan P, Pramatarova A, Quang DA, Adoue V, Busche S, Caron M, Djambazian H, Bemmo A, Fontebasso AM, Spence T, Schwartzentruber J, Albrecht S, Hauser P, Garami M, Klekner A, Bognar L, Montes JL, Staffa A, Montpetit A, Berube P, Zakrzewska M, Zakrzewski K, Liberski PP, Dong Z, Siegel PM, Duchaine T, Perotti C, Fleming A, Faury D, Remke M, Gallo M, Dirks P, Taylor MD, Sladek R, Pastinen T, Chan JA, Huang A, Majewski J, Jabado N
Nature genetics46(1)39-44(2014 Jan)

Genome-wide association study identifies loci affecting blood copper, selenium and zinc.
Evans DM, Zhu G, Dy V, Heath AC, Madden PA, Kemp JP, McMahon G, St Pourcain B, Timpson NJ, Golding J, Lawlor DA, Steer C, Montgomery GW, Martin NG, Smith GD, Whitfield JB
Human molecular genetics22(19)3998-4006(2013 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

In this report, we identify tweety-homolog 1 (Ttyh1), a membrane protein linked to neuronal development, as a potent driver of tumor microtube (TM)-mediated brain colonization by glioma cells.
Title: Tweety-Homolog 1 Drives Brain Colonization of Gliomas.

TTYH1 was not expressed in either the malignant or the control samples
Title: Validation of analytical breast cancer microarray analysis in medical laboratory.

Fusion of TTYH1 with the C19MC microRNA cluster drives expression of a brain-specific DNMT3B isoform in the embryonal brain tumor.
Title: Fusion of TTYH1 with the C19MC microRNA cluster drives expression of a brain-specific DNMT3B isoform in the embryonal brain tumor ETMR.

Nedd4-2 differentially interacts with and regulates TTYH1-3
Title: The ubiquitin-protein ligase Nedd4-2 differentially interacts with and regulates members of the Tweety family of chloride ion channels.

The following TTYH1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TTYH1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu14790	NM_001005367.3 Latest version!	Homo sapiens tweety family member 1 (TTYH1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu13790	NM_020659.4 Latest version!	Homo sapiens tweety family member 1 (TTYH1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu14002	NM_001201461.2 Latest version!	Homo sapiens tweety family member 1 (TTYH1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu70429	XM_017027025.1 Latest version!	Homo sapiens tweety family member 1 (TTYH1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu88589	XM_017027026.1 Latest version!	Homo sapiens tweety family member 1 (TTYH1), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
View Old Accession Versions >>
OHu13790	NM_020659.3	Homo sapiens tweety family member 1 (TTYH1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu14002	NM_001201461.1	Homo sapiens tweety family member 1 (TTYH1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu14790	NM_001005367.2	Homo sapiens tweety family member 1 (TTYH1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TTYH1 ( NM_001005367.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001005367.1 Homo sapiens tweety family member 1 (TTYH1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu14790
Clone ID Related Accession (Same CDS sequence)	NM_001005367.2 , NM_001005367.3
Accession Version	NM_001005367.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1383bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Homo sapiens(human)
Product	protein tweety homolog 1 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AB188496.1, AK289468.1, AC245884.3, AF177909.1 and BU737336.1. On Jan 21, 2011 this sequence version replaced NM_001005367.1. Transcript Variant: This variant (2), also known as hTTYH1s, encodes the longest isoform (2). ##Evidence-Data-START## Transcript exon combination :: BC011347.1, SRR1803615.214111.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END##

ATGGGGGCGC CCCCGGGCTA CCGGCCCTCA GCTTGGGTGC ATCTCCTCCA CCAGCTGCCC 
CGCGCCGACT TCCAGCTCCG CCCGGTGCCC AGCGTTTTCG CGCCCCAAGA GCAGGAATAC 
CAGCAGGCCT TGTTGCTGGT GGCGGCCTTG GCGGGCCTGG GCTTGGGCCT GAGCCTCATT 
TTCATCGCTG TCTACCTCAT CCGCTTCTGC TGCTGCCGGC CCCCCGAGCC CCCCGGGTCC 
AAGATCCCCT CGCCCGGGGG AGGCTGCGTC ACCTGGAGCT GCATTGTCGC CCTTCTCGCC 
GGCTGCACTG GCATTGGCAT CGGTTTCTAT GGCAACAGTG AGACCAGTGA TGGGGTGTCC 
CAGCTCAGCT CTGCGCTGCT GCACGCCAAC CACACACTCA GCACCATTGA CCACCTGGTG 
TTGGAGACGG TGGAGAGGCT GGGCGAGGCG GTGAGGACAG AGCTGACCAC CCTGGAGGAG 
GTGCTCGAGC CGCGCACGGA GCTGGTGGCT GCCGCCCGAG GGGCTCGACG GCAGGCGGAG 
GCTGCGGCCC AGCAGCTGCA GGGGCTGGCC TTCTGGCAGG GAGTGCCCCT GAGCCCCCTG 
CAGGTGGCTG AAAATGTGTC CTTTGTGGAG GAGTACAGGT GGCTGGCCTA CGTCCTCCTG 
CTGCTCCTGG AGCTGCTGGT CTGCCTCTTC ACCCTCCTGG GCCTGGCGAA GCAGAGCAAG 
TGGCTGGTGA TCGTGATGAC AGTCATGAGT CTCCTGGTTC TCGTCCTGAG CTGGGGCTCC 
ATGGGCCTGG AGGCAGCCAC GGCCGTGGGC CTCAGTGACT TCTGCTCCAA TCCAGACCCT 
TATGTTCTGA ACCTGACCCA GGAGGAGACA GGGCTCAGCT CAGACATCCT GAGCTATTAT 
CTCCTCTGCA ACCGGGCCGT CTCCAACCCC TTCCAACAGA GGCTGACTCT GTCCCAGCGA 
GCTCTGGCCA ACATCCACTC CCAGCTGCTG GGCCTGGAGC GAGAAGCTGT GCCTCAGTTC 
CCTTCAGCGC AGAAGCCTCT GCTGTCCTTG GAGGAGACTC TGAATGTGAC AGAAGGAAAT 
TTCCACCAGT TGGTGGCACT GCTACACTGC CGCAGCCTGC ACAAGGACTA TGGTGCAGCC 
CTGCGGGGCC TGTGCGAAGA CGCCCTGGAA GGCCTGCTCT TCCTGCTACT CTTCTCCCTG 
CTGTCTGCAG GAGCGCTGGC CACTGCCCTC TGCAGCCTGC CCCGAGCCTG GGCCCTCTTC 
CCACCCAGGA ATCCAAGCGC TTTGTGCAGT GGCAGTCGTC TATCTGAGCC CCTCCTCCCG 
GCTGGACTGG AGCCTGGCTC CCCTCTTCGT TCCTTCCCTG GCTGCCGGAG GAGACCCCAC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001005367.1
CDS	123..1505
Translation	MGAPPGYRPSAWVHLLHQLPRADFQLRPVPSVFAPQEQEYQQALLLVAALAGLGLGLSLIFIAVYLIRFCCCRPPEPPGSKIPSPGGGCVTWSCIVALLAGCTGIGIGFYGNSETSDGVSQLSSALLHANHTLSTIDHLVLETVERLGEAVRTELTTLEEVLEPRTELVAAARGARRQAEAAAQQLQGLAFWQGVPLSPLQVAENVSFVEEYRWLAYVLLLLLELLVCLFTLLGLAKQSKWLVIVMTVMSLLVLVLSWGSMGLEAATAVGLSDFCSNPDPYVLNLTQEETGLSSDILSYYLLCNRAVSNPFQQRLTLSQRALANIHSQLLGLEREAVPQFPSAQKPLLSLEETLNVTEGNFHQLVALLHCRSLHKDYGAALRGLCEDALEGLLFLLLFSLLSAGALATALCSLPRAWALFPPRNPSALCSGSRLSEPLLPAGLEPGSPLRSFPGCRRRPH

Target ORF information:

RefSeq Version	NM_001005367.2
Organism	Homo sapiens(human)
Definition	Homo sapiens tweety family member 1 (TTYH1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001005367.2

ORF Insert Sequence:

ATGGGGGCGC CCCCGGGCTA CCGGCCCTCA GCTTGGGTGC ATCTCCTCCA CCAGCTGCCC 
CGCGCCGACT TCCAGCTCCG CCCGGTGCCC AGCGTTTTCG CGCCCCAAGA GCAGGAATAC 
CAGCAGGCCT TGTTGCTGGT GGCGGCCTTG GCGGGCCTGG GCTTGGGCCT GAGCCTCATT 
TTCATCGCTG TCTACCTCAT CCGCTTCTGC TGCTGCCGGC CCCCCGAGCC CCCCGGGTCC 
AAGATCCCCT CGCCCGGGGG AGGCTGCGTC ACCTGGAGCT GCATTGTCGC CCTTCTCGCC 
GGCTGCACTG GCATTGGCAT CGGTTTCTAT GGCAACAGTG AGACCAGTGA TGGGGTGTCC 
CAGCTCAGCT CTGCGCTGCT GCACGCCAAC CACACACTCA GCACCATTGA CCACCTGGTG 
TTGGAGACGG TGGAGAGGCT GGGCGAGGCG GTGAGGACAG AGCTGACCAC CCTGGAGGAG 
GTGCTCGAGC CGCGCACGGA GCTGGTGGCT GCCGCCCGAG GGGCTCGACG GCAGGCGGAG 
GCTGCGGCCC AGCAGCTGCA GGGGCTGGCC TTCTGGCAGG GAGTGCCCCT GAGCCCCCTG 
CAGGTGGCTG AAAATGTGTC CTTTGTGGAG GAGTACAGGT GGCTGGCCTA CGTCCTCCTG 
CTGCTCCTGG AGCTGCTGGT CTGCCTCTTC ACCCTCCTGG GCCTGGCGAA GCAGAGCAAG 
TGGCTGGTGA TCGTGATGAC AGTCATGAGT CTCCTGGTTC TCGTCCTGAG CTGGGGCTCC 
ATGGGCCTGG AGGCAGCCAC GGCCGTGGGC CTCAGTGACT TCTGCTCCAA TCCAGACCCT 
TATGTTCTGA ACCTGACCCA GGAGGAGACA GGGCTCAGCT CAGACATCCT GAGCTATTAT 
CTCCTCTGCA ACCGGGCCGT CTCCAACCCC TTCCAACAGA GGCTGACTCT GTCCCAGCGA 
GCTCTGGCCA ACATCCACTC CCAGCTGCTG GGCCTGGAGC GAGAAGCTGT GCCTCAGTTC 
CCTTCAGCGC AGAAGCCTCT GCTGTCCTTG GAGGAGACTC TGAATGTGAC AGAAGGAAAT 
TTCCACCAGT TGGTGGCACT GCTACACTGC CGCAGCCTGC ACAAGGACTA TGGTGCAGCC 
CTGCGGGGCC TGTGCGAAGA CGCCCTGGAA GGCCTGCTCT TCCTGCTACT CTTCTCCCTG 
CTGTCTGCAG GAGCGCTGGC CACTGCCCTC TGCAGCCTGC CCCGAGCCTG GGCCCTCTTC 
CCACCCAGGA ATCCAAGCGC TTTGTGCAGT GGCAGTCGTC TATCTGAGCC CCTCCTCCCG 
GCTGGACTGG AGCCTGGCTC CCCTCTTCGT TCCTTCCCTG GCTGCCGGAG GAGACCCCAC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TTYH1 ( NM_001005367.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001005367.1 Homo sapiens tweety family member 1 (TTYH1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu14790
Clone ID Related Accession (Same CDS sequence)	NM_001005367.2 , NM_001005367.3
Accession Version	NM_001005367.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1383bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-27
Organism	Homo sapiens(human)
Product	protein tweety homolog 1 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AB188496.1, AK289468.1, AC245884.3, AF177909.1 and BU737336.1. On May 31, 2019 this sequence version replaced NM_001005367.2. Transcript Variant: This variant (2), also known as hTTYH1s, encodes the longest isoform (2). ##Evidence-Data-START## Transcript exon combination :: SRR7410570.659301.1, BC011347.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END##

ATGGGGGCGC CCCCGGGCTA CCGGCCCTCA GCTTGGGTGC ATCTCCTCCA CCAGCTGCCC 
CGCGCCGACT TCCAGCTCCG CCCGGTGCCC AGCGTTTTCG CGCCCCAAGA GCAGGAATAC 
CAGCAGGCCT TGTTGCTGGT GGCGGCCTTG GCGGGCCTGG GCTTGGGCCT GAGCCTCATT 
TTCATCGCTG TCTACCTCAT CCGCTTCTGC TGCTGCCGGC CCCCCGAGCC CCCCGGGTCC 
AAGATCCCCT CGCCCGGGGG AGGCTGCGTC ACCTGGAGCT GCATTGTCGC CCTTCTCGCC 
GGCTGCACTG GCATTGGCAT CGGTTTCTAT GGCAACAGTG AGACCAGTGA TGGGGTGTCC 
CAGCTCAGCT CTGCGCTGCT GCACGCCAAC CACACACTCA GCACCATTGA CCACCTGGTG 
TTGGAGACGG TGGAGAGGCT GGGCGAGGCG GTGAGGACAG AGCTGACCAC CCTGGAGGAG 
GTGCTCGAGC CGCGCACGGA GCTGGTGGCT GCCGCCCGAG GGGCTCGACG GCAGGCGGAG 
GCTGCGGCCC AGCAGCTGCA GGGGCTGGCC TTCTGGCAGG GAGTGCCCCT GAGCCCCCTG 
CAGGTGGCTG AAAATGTGTC CTTTGTGGAG GAGTACAGGT GGCTGGCCTA CGTCCTCCTG 
CTGCTCCTGG AGCTGCTGGT CTGCCTCTTC ACCCTCCTGG GCCTGGCGAA GCAGAGCAAG 
TGGCTGGTGA TCGTGATGAC AGTCATGAGT CTCCTGGTTC TCGTCCTGAG CTGGGGCTCC 
ATGGGCCTGG AGGCAGCCAC GGCCGTGGGC CTCAGTGACT TCTGCTCCAA TCCAGACCCT 
TATGTTCTGA ACCTGACCCA GGAGGAGACA GGGCTCAGCT CAGACATCCT GAGCTATTAT 
CTCCTCTGCA ACCGGGCCGT CTCCAACCCC TTCCAACAGA GGCTGACTCT GTCCCAGCGA 
GCTCTGGCCA ACATCCACTC CCAGCTGCTG GGCCTGGAGC GAGAAGCTGT GCCTCAGTTC 
CCTTCAGCGC AGAAGCCTCT GCTGTCCTTG GAGGAGACTC TGAATGTGAC AGAAGGAAAT 
TTCCACCAGT TGGTGGCACT GCTACACTGC CGCAGCCTGC ACAAGGACTA TGGTGCAGCC 
CTGCGGGGCC TGTGCGAAGA CGCCCTGGAA GGCCTGCTCT TCCTGCTACT CTTCTCCCTG 
CTGTCTGCAG GAGCGCTGGC CACTGCCCTC TGCAGCCTGC CCCGAGCCTG GGCCCTCTTC 
CCACCCAGGA ATCCAAGCGC TTTGTGCAGT GGCAGTCGTC TATCTGAGCC CCTCCTCCCG 
GCTGGACTGG AGCCTGGCTC CCCTCTTCGT TCCTTCCCTG GCTGCCGGAG GAGACCCCAC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001005367.1
CDS	90..1472
Translation	MGAPPGYRPSAWVHLLHQLPRADFQLRPVPSVFAPQEQEYQQALLLVAALAGLGLGLSLIFIAVYLIRFCCCRPPEPPGSKIPSPGGGCVTWSCIVALLAGCTGIGIGFYGNSETSDGVSQLSSALLHANHTLSTIDHLVLETVERLGEAVRTELTTLEEVLEPRTELVAAARGARRQAEAAAQQLQGLAFWQGVPLSPLQVAENVSFVEEYRWLAYVLLLLLELLVCLFTLLGLAKQSKWLVIVMTVMSLLVLVLSWGSMGLEAATAVGLSDFCSNPDPYVLNLTQEETGLSSDILSYYLLCNRAVSNPFQQRLTLSQRALANIHSQLLGLEREAVPQFPSAQKPLLSLEETLNVTEGNFHQLVALLHCRSLHKDYGAALRGLCEDALEGLLFLLLFSLLSAGALATALCSLPRAWALFPPRNPSALCSGSRLSEPLLPAGLEPGSPLRSFPGCRRRPH

Target ORF information:

RefSeq Version	NM_001005367.3
Organism	Homo sapiens(human)
Definition	Homo sapiens tweety family member 1 (TTYH1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001005367.3

ORF Insert Sequence:

ATGGGGGCGC CCCCGGGCTA CCGGCCCTCA GCTTGGGTGC ATCTCCTCCA CCAGCTGCCC 
CGCGCCGACT TCCAGCTCCG CCCGGTGCCC AGCGTTTTCG CGCCCCAAGA GCAGGAATAC 
CAGCAGGCCT TGTTGCTGGT GGCGGCCTTG GCGGGCCTGG GCTTGGGCCT GAGCCTCATT 
TTCATCGCTG TCTACCTCAT CCGCTTCTGC TGCTGCCGGC CCCCCGAGCC CCCCGGGTCC 
AAGATCCCCT CGCCCGGGGG AGGCTGCGTC ACCTGGAGCT GCATTGTCGC CCTTCTCGCC 
GGCTGCACTG GCATTGGCAT CGGTTTCTAT GGCAACAGTG AGACCAGTGA TGGGGTGTCC 
CAGCTCAGCT CTGCGCTGCT GCACGCCAAC CACACACTCA GCACCATTGA CCACCTGGTG 
TTGGAGACGG TGGAGAGGCT GGGCGAGGCG GTGAGGACAG AGCTGACCAC CCTGGAGGAG 
GTGCTCGAGC CGCGCACGGA GCTGGTGGCT GCCGCCCGAG GGGCTCGACG GCAGGCGGAG 
GCTGCGGCCC AGCAGCTGCA GGGGCTGGCC TTCTGGCAGG GAGTGCCCCT GAGCCCCCTG 
CAGGTGGCTG AAAATGTGTC CTTTGTGGAG GAGTACAGGT GGCTGGCCTA CGTCCTCCTG 
CTGCTCCTGG AGCTGCTGGT CTGCCTCTTC ACCCTCCTGG GCCTGGCGAA GCAGAGCAAG 
TGGCTGGTGA TCGTGATGAC AGTCATGAGT CTCCTGGTTC TCGTCCTGAG CTGGGGCTCC 
ATGGGCCTGG AGGCAGCCAC GGCCGTGGGC CTCAGTGACT TCTGCTCCAA TCCAGACCCT 
TATGTTCTGA ACCTGACCCA GGAGGAGACA GGGCTCAGCT CAGACATCCT GAGCTATTAT 
CTCCTCTGCA ACCGGGCCGT CTCCAACCCC TTCCAACAGA GGCTGACTCT GTCCCAGCGA 
GCTCTGGCCA ACATCCACTC CCAGCTGCTG GGCCTGGAGC GAGAAGCTGT GCCTCAGTTC 
CCTTCAGCGC AGAAGCCTCT GCTGTCCTTG GAGGAGACTC TGAATGTGAC AGAAGGAAAT 
TTCCACCAGT TGGTGGCACT GCTACACTGC CGCAGCCTGC ACAAGGACTA TGGTGCAGCC 
CTGCGGGGCC TGTGCGAAGA CGCCCTGGAA GGCCTGCTCT TCCTGCTACT CTTCTCCCTG 
CTGTCTGCAG GAGCGCTGGC CACTGCCCTC TGCAGCCTGC CCCGAGCCTG GGCCCTCTTC 
CCACCCAGGA ATCCAAGCGC TTTGTGCAGT GGCAGTCGTC TATCTGAGCC CCTCCTCCCG 
GCTGGACTGG AGCCTGGCTC CCCTCTTCGT TCCTTCCCTG GCTGCCGGAG GAGACCCCAC 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TTYH1 ( NM_020659.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_065710.1 Homo sapiens tweety family member 1 (TTYH1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu13790
Clone ID Related Accession (Same CDS sequence)	NM_020659.4 , NM_020659.3
Accession Version	NM_020659.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1353bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-25
Organism	Homo sapiens(human)
Product	protein tweety homolog 1 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AB188496.1, AF177909.1, BU737336.1 and AC245884.3. On May 17, 2019 this sequence version replaced NM_020659.3. Transcript Variant: This variant (1) contains an alternate exon compared to variant 2, that causes a frameshift. The resulting isoform (1) has a shorter and distinct C-terminus compared to isoform 2. ##Evidence-Data-START## Transcript exon combination :: SRR7410570.659303.1, SRR3476690.32643.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000376530.8/ ENSP00000365713.3 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGGGGCGC CCCCGGGCTA CCGGCCCTCA GCTTGGGTGC ATCTCCTCCA CCAGCTGCCC 
CGCGCCGACT TCCAGCTCCG CCCGGTGCCC AGCGTTTTCG CGCCCCAAGA GCAGGAATAC 
CAGCAGGCCT TGTTGCTGGT GGCGGCCTTG GCGGGCCTGG GCTTGGGCCT GAGCCTCATT 
TTCATCGCTG TCTACCTCAT CCGCTTCTGC TGCTGCCGGC CCCCCGAGCC CCCCGGGTCC 
AAGATCCCCT CGCCCGGGGG AGGCTGCGTC ACCTGGAGCT GCATTGTCGC CCTTCTCGCC 
GGCTGCACTG GCATTGGCAT CGGTTTCTAT GGCAACAGTG AGACCAGTGA TGGGGTGTCC 
CAGCTCAGCT CTGCGCTGCT GCACGCCAAC CACACACTCA GCACCATTGA CCACCTGGTG 
TTGGAGACGG TGGAGAGGCT GGGCGAGGCG GTGAGGACAG AGCTGACCAC CCTGGAGGAG 
GTGCTCGAGC CGCGCACGGA GCTGGTGGCT GCCGCCCGAG GGGCTCGACG GCAGGCGGAG 
GCTGCGGCCC AGCAGCTGCA GGGGCTGGCC TTCTGGCAGG GAGTGCCCCT GAGCCCCCTG 
CAGGTGGCTG AAAATGTGTC CTTTGTGGAG GAGTACAGGT GGCTGGCCTA CGTCCTCCTG 
CTGCTCCTGG AGCTGCTGGT CTGCCTCTTC ACCCTCCTGG GCCTGGCGAA GCAGAGCAAG 
TGGCTGGTGA TCGTGATGAC AGTCATGAGT CTCCTGGTTC TCGTCCTGAG CTGGGGCTCC 
ATGGGCCTGG AGGCAGCCAC GGCCGTGGGC CTCAGTGACT TCTGCTCCAA TCCAGACCCT 
TATGTTCTGA ACCTGACCCA GGAGGAGACA GGGCTCAGCT CAGACATCCT GAGCTATTAT 
CTCCTCTGCA ACCGGGCCGT CTCCAACCCC TTCCAACAGA GGCTGACTCT GTCCCAGCGA 
GCTCTGGCCA ACATCCACTC CCAGCTGCTG GGCCTGGAGC GAGAAGCTGT GCCTCAGTTC 
CCTTCAGCGC AGAAGCCTCT GCTGTCCTTG GAGGAGACTC TGAATGTGAC AGAAGGAAAT 
TTCCACCAGT TGGTGGCACT GCTACACTGC CGCAGCCTGC ACAAGGACTA TGGTGCAGCC 
CTGCGGGGCC TGTGCGAAGA CGCCCTGGAA GGCCTGCTCT TCCTGCTACT CTTCTCCCTG 
CTGTCTGCAG GAGCGCTGGC CACTGCCCTC TGCAGCCTGC CCCGAGCCTG GGCCCTCTTC 
CCACCCAGTG ACGACTACGA TGACACAGAC GATGACGACC CTTTCAACCC TCAGGAATCC 
AAGCGCTTTG TGCAGTGGCA GTCGTCTATC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_065710.1
CDS	90..1442
Translation	MGAPPGYRPSAWVHLLHQLPRADFQLRPVPSVFAPQEQEYQQALLLVAALAGLGLGLSLIFIAVYLIRFCCCRPPEPPGSKIPSPGGGCVTWSCIVALLAGCTGIGIGFYGNSETSDGVSQLSSALLHANHTLSTIDHLVLETVERLGEAVRTELTTLEEVLEPRTELVAAARGARRQAEAAAQQLQGLAFWQGVPLSPLQVAENVSFVEEYRWLAYVLLLLLELLVCLFTLLGLAKQSKWLVIVMTVMSLLVLVLSWGSMGLEAATAVGLSDFCSNPDPYVLNLTQEETGLSSDILSYYLLCNRAVSNPFQQRLTLSQRALANIHSQLLGLEREAVPQFPSAQKPLLSLEETLNVTEGNFHQLVALLHCRSLHKDYGAALRGLCEDALEGLLFLLLFSLLSAGALATALCSLPRAWALFPPSDDYDDTDDDDPFNPQESKRFVQWQSSI

Target ORF information:

RefSeq Version	NM_020659.4
Organism	Homo sapiens(human)
Definition	Homo sapiens tweety family member 1 (TTYH1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_020659.4

ORF Insert Sequence:

ATGGGGGCGC CCCCGGGCTA CCGGCCCTCA GCTTGGGTGC ATCTCCTCCA CCAGCTGCCC 
CGCGCCGACT TCCAGCTCCG CCCGGTGCCC AGCGTTTTCG CGCCCCAAGA GCAGGAATAC 
CAGCAGGCCT TGTTGCTGGT GGCGGCCTTG GCGGGCCTGG GCTTGGGCCT GAGCCTCATT 
TTCATCGCTG TCTACCTCAT CCGCTTCTGC TGCTGCCGGC CCCCCGAGCC CCCCGGGTCC 
AAGATCCCCT CGCCCGGGGG AGGCTGCGTC ACCTGGAGCT GCATTGTCGC CCTTCTCGCC 
GGCTGCACTG GCATTGGCAT CGGTTTCTAT GGCAACAGTG AGACCAGTGA TGGGGTGTCC 
CAGCTCAGCT CTGCGCTGCT GCACGCCAAC CACACACTCA GCACCATTGA CCACCTGGTG 
TTGGAGACGG TGGAGAGGCT GGGCGAGGCG GTGAGGACAG AGCTGACCAC CCTGGAGGAG 
GTGCTCGAGC CGCGCACGGA GCTGGTGGCT GCCGCCCGAG GGGCTCGACG GCAGGCGGAG 
GCTGCGGCCC AGCAGCTGCA GGGGCTGGCC TTCTGGCAGG GAGTGCCCCT GAGCCCCCTG 
CAGGTGGCTG AAAATGTGTC CTTTGTGGAG GAGTACAGGT GGCTGGCCTA CGTCCTCCTG 
CTGCTCCTGG AGCTGCTGGT CTGCCTCTTC ACCCTCCTGG GCCTGGCGAA GCAGAGCAAG 
TGGCTGGTGA TCGTGATGAC AGTCATGAGT CTCCTGGTTC TCGTCCTGAG CTGGGGCTCC 
ATGGGCCTGG AGGCAGCCAC GGCCGTGGGC CTCAGTGACT TCTGCTCCAA TCCAGACCCT 
TATGTTCTGA ACCTGACCCA GGAGGAGACA GGGCTCAGCT CAGACATCCT GAGCTATTAT 
CTCCTCTGCA ACCGGGCCGT CTCCAACCCC TTCCAACAGA GGCTGACTCT GTCCCAGCGA 
GCTCTGGCCA ACATCCACTC CCAGCTGCTG GGCCTGGAGC GAGAAGCTGT GCCTCAGTTC 
CCTTCAGCGC AGAAGCCTCT GCTGTCCTTG GAGGAGACTC TGAATGTGAC AGAAGGAAAT 
TTCCACCAGT TGGTGGCACT GCTACACTGC CGCAGCCTGC ACAAGGACTA TGGTGCAGCC 
CTGCGGGGCC TGTGCGAAGA CGCCCTGGAA GGCCTGCTCT TCCTGCTACT CTTCTCCCTG 
CTGTCTGCAG GAGCGCTGGC CACTGCCCTC TGCAGCCTGC CCCGAGCCTG GGCCCTCTTC 
CCACCCAGTG ACGACTACGA TGACACAGAC GATGACGACC CTTTCAACCC TCAGGAATCC 
AAGCGCTTTG TGCAGTGGCA GTCGTCTATC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TTYH1 ( NM_020659.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_065710.1 Homo sapiens tweety family member 1 (TTYH1), transcript variant 1, mRNA.

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CloneID	OHu13790
Clone ID Related Accession (Same CDS sequence)	NM_020659.4 , NM_020659.3
Accession Version	NM_020659.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1353bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Homo sapiens(human)
Product	protein tweety homolog 1 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AB188496.1, AF177909.1 and BU737336.1. On Jan 21, 2011 this sequence version replaced NM_020659.2. Transcript Variant: This variant (1) contains an alternate exon compared to variant 2, that causes a frameshift. The resulting isoform (1) has a shorter and distinct C-terminus compared to isoform 2. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.145187.1, SRR1803615.224057.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGGGCGC CCCCGGGCTA CCGGCCCTCA GCTTGGGTGC ATCTCCTCCA CCAGCTGCCC 
CGCGCCGACT TCCAGCTCCG CCCGGTGCCC AGCGTTTTCG CGCCCCAAGA GCAGGAATAC 
CAGCAGGCCT TGTTGCTGGT GGCGGCCTTG GCGGGCCTGG GCTTGGGCCT GAGCCTCATT 
TTCATCGCTG TCTACCTCAT CCGCTTCTGC TGCTGCCGGC CCCCCGAGCC CCCCGGGTCC 
AAGATCCCCT CGCCCGGGGG AGGCTGCGTC ACCTGGAGCT GCATTGTCGC CCTTCTCGCC 
GGCTGCACTG GCATTGGCAT CGGTTTCTAT GGCAACAGTG AGACCAGTGA TGGGGTGTCC 
CAGCTCAGCT CTGCGCTGCT GCACGCCAAC CACACACTCA GCACCATTGA CCACCTGGTG 
TTGGAGACGG TGGAGAGGCT GGGCGAGGCG GTGAGGACAG AGCTGACCAC CCTGGAGGAG 
GTGCTCGAGC CGCGCACGGA GCTGGTGGCT GCCGCCCGAG GGGCTCGACG GCAGGCGGAG 
GCTGCGGCCC AGCAGCTGCA GGGGCTGGCC TTCTGGCAGG GAGTGCCCCT GAGCCCCCTG 
CAGGTGGCTG AAAATGTGTC CTTTGTGGAG GAGTACAGGT GGCTGGCCTA CGTCCTCCTG 
CTGCTCCTGG AGCTGCTGGT CTGCCTCTTC ACCCTCCTGG GCCTGGCGAA GCAGAGCAAG 
TGGCTGGTGA TCGTGATGAC AGTCATGAGT CTCCTGGTTC TCGTCCTGAG CTGGGGCTCC 
ATGGGCCTGG AGGCAGCCAC GGCCGTGGGC CTCAGTGACT TCTGCTCCAA TCCAGACCCT 
TATGTTCTGA ACCTGACCCA GGAGGAGACA GGGCTCAGCT CAGACATCCT GAGCTATTAT 
CTCCTCTGCA ACCGGGCCGT CTCCAACCCC TTCCAACAGA GGCTGACTCT GTCCCAGCGA 
GCTCTGGCCA ACATCCACTC CCAGCTGCTG GGCCTGGAGC GAGAAGCTGT GCCTCAGTTC 
CCTTCAGCGC AGAAGCCTCT GCTGTCCTTG GAGGAGACTC TGAATGTGAC AGAAGGAAAT 
TTCCACCAGT TGGTGGCACT GCTACACTGC CGCAGCCTGC ACAAGGACTA TGGTGCAGCC 
CTGCGGGGCC TGTGCGAAGA CGCCCTGGAA GGCCTGCTCT TCCTGCTACT CTTCTCCCTG 
CTGTCTGCAG GAGCGCTGGC CACTGCCCTC TGCAGCCTGC CCCGAGCCTG GGCCCTCTTC 
CCACCCAGTG ACGACTACGA TGACACAGAC GATGACGACC CTTTCAACCC TCAGGAATCC 
AAGCGCTTTG TGCAGTGGCA GTCGTCTATC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_065710.1
CDS	123..1475
Translation	MGAPPGYRPSAWVHLLHQLPRADFQLRPVPSVFAPQEQEYQQALLLVAALAGLGLGLSLIFIAVYLIRFCCCRPPEPPGSKIPSPGGGCVTWSCIVALLAGCTGIGIGFYGNSETSDGVSQLSSALLHANHTLSTIDHLVLETVERLGEAVRTELTTLEEVLEPRTELVAAARGARRQAEAAAQQLQGLAFWQGVPLSPLQVAENVSFVEEYRWLAYVLLLLLELLVCLFTLLGLAKQSKWLVIVMTVMSLLVLVLSWGSMGLEAATAVGLSDFCSNPDPYVLNLTQEETGLSSDILSYYLLCNRAVSNPFQQRLTLSQRALANIHSQLLGLEREAVPQFPSAQKPLLSLEETLNVTEGNFHQLVALLHCRSLHKDYGAALRGLCEDALEGLLFLLLFSLLSAGALATALCSLPRAWALFPPSDDYDDTDDDDPFNPQESKRFVQWQSSI

Target ORF information:

RefSeq Version	NM_020659.3
Organism	Homo sapiens(human)
Definition	Homo sapiens tweety family member 1 (TTYH1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_020659.3

ORF Insert Sequence:

ATGGGGGCGC CCCCGGGCTA CCGGCCCTCA GCTTGGGTGC ATCTCCTCCA CCAGCTGCCC 
CGCGCCGACT TCCAGCTCCG CCCGGTGCCC AGCGTTTTCG CGCCCCAAGA GCAGGAATAC 
CAGCAGGCCT TGTTGCTGGT GGCGGCCTTG GCGGGCCTGG GCTTGGGCCT GAGCCTCATT 
TTCATCGCTG TCTACCTCAT CCGCTTCTGC TGCTGCCGGC CCCCCGAGCC CCCCGGGTCC 
AAGATCCCCT CGCCCGGGGG AGGCTGCGTC ACCTGGAGCT GCATTGTCGC CCTTCTCGCC 
GGCTGCACTG GCATTGGCAT CGGTTTCTAT GGCAACAGTG AGACCAGTGA TGGGGTGTCC 
CAGCTCAGCT CTGCGCTGCT GCACGCCAAC CACACACTCA GCACCATTGA CCACCTGGTG 
TTGGAGACGG TGGAGAGGCT GGGCGAGGCG GTGAGGACAG AGCTGACCAC CCTGGAGGAG 
GTGCTCGAGC CGCGCACGGA GCTGGTGGCT GCCGCCCGAG GGGCTCGACG GCAGGCGGAG 
GCTGCGGCCC AGCAGCTGCA GGGGCTGGCC TTCTGGCAGG GAGTGCCCCT GAGCCCCCTG 
CAGGTGGCTG AAAATGTGTC CTTTGTGGAG GAGTACAGGT GGCTGGCCTA CGTCCTCCTG 
CTGCTCCTGG AGCTGCTGGT CTGCCTCTTC ACCCTCCTGG GCCTGGCGAA GCAGAGCAAG 
TGGCTGGTGA TCGTGATGAC AGTCATGAGT CTCCTGGTTC TCGTCCTGAG CTGGGGCTCC 
ATGGGCCTGG AGGCAGCCAC GGCCGTGGGC CTCAGTGACT TCTGCTCCAA TCCAGACCCT 
TATGTTCTGA ACCTGACCCA GGAGGAGACA GGGCTCAGCT CAGACATCCT GAGCTATTAT 
CTCCTCTGCA ACCGGGCCGT CTCCAACCCC TTCCAACAGA GGCTGACTCT GTCCCAGCGA 
GCTCTGGCCA ACATCCACTC CCAGCTGCTG GGCCTGGAGC GAGAAGCTGT GCCTCAGTTC 
CCTTCAGCGC AGAAGCCTCT GCTGTCCTTG GAGGAGACTC TGAATGTGAC AGAAGGAAAT 
TTCCACCAGT TGGTGGCACT GCTACACTGC CGCAGCCTGC ACAAGGACTA TGGTGCAGCC 
CTGCGGGGCC TGTGCGAAGA CGCCCTGGAA GGCCTGCTCT TCCTGCTACT CTTCTCCCTG 
CTGTCTGCAG GAGCGCTGGC CACTGCCCTC TGCAGCCTGC CCCGAGCCTG GGCCCTCTTC 
CCACCCAGTG ACGACTACGA TGACACAGAC GATGACGACC CTTTCAACCC TCAGGAATCC 
AAGCGCTTTG TGCAGTGGCA GTCGTCTATC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TTYH1 ( NM_001201461.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001188390.1 Homo sapiens tweety family member 1 (TTYH1), transcript variant 3, mRNA.

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CloneID	OHu14002
Clone ID Related Accession (Same CDS sequence)	NM_001201461.1 , NM_001201461.2
Accession Version	NM_001201461.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1356bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Homo sapiens(human)
Product	protein tweety homolog 1 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AB188496.1 and BU737336.1. Transcript Variant: This variant (3) uses an alternate in-frame splice junction at the 5' end of an exon and contains an alternate exon compared to variant 2, that causes a frameshift. The resulting isoform (1) has a shorter and distinct C-terminus compared to isoform 2. ##Evidence-Data-START## Transcript exon combination :: AB188496.1, SRR1803613.176626.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2145743 [ECO:0000348] ##Evidence-Data-END##

ATGGGGGCGC CCCCGGGCTA CCGGCCCTCA GCTTGGGTGC ATCTCCTCCA CCAGCTGCCC 
CGCGCCGACT TCCAGCTCCG CCCGGTGCCC AGCGTTTTCG CGCCCCAAGA GCAGGAATAC 
CAGCAGGCCT TGTTGCTGGT GGCGGCCTTG GCGGGCCTGG GCTTGGGCCT GAGCCTCATT 
TTCATCGCTG TCTACCTCAT CCGCTTCTGC TGCTGCCGGC CCCCCGAGCC CCCCGGGTCC 
AAGATCCCCT CGCCCGGGGG AGGCTGCGTC ACCTGGAGCT GCATTGTCGC CCTTCTCGCC 
GGCTGCACTG GCATTGGCAT CGGTTTCTAT GGCAACAGTG AGACCAGTGA TGGGGTGTCC 
CAGCTCAGCT CTGCGCTGCT GCACGCCAAC CACACACTCA GCACCATTGA CCACCTGGTG 
TTGGAGACGG TGGAGAGGCT GGGCGAGGCG GTGAGGACAG AGCTGACCAC CCTGGAGGAG 
GTGCTCGAGC CGCGCACGGA GCTGGTGGCT GCCGCCCGAG GGGCTCGACG GCAGGCGGAG 
GCTGCGGCCC AGCAGCTGCA GGGGCTGGCC TTCTGGCAGG GAGTGCCCCT GAGCCCCCTG 
CAGGTGGCTG AAAATGTGTC CTTTGTGGAG GAGTACAGGT GGCTGGCCTA CGTCCTCCTG 
CTGCTCCTGG AGCTGCTGGT CTGCCTCTTC ACCCTCCTGG GCCTGGCGAA GCAGAGCAAG 
TGGCTGGTGA TCGTGATGAC AGTCATGAGT CTCCTGGTTC TCGTCCTGAG CTGGGGCTCC 
ATGGGCCTGG AGGCAGCCAC GGCCGTGGGC CTCAGTGACT TCTGCTCCAA TCCAGACCCT 
TATGTTCTGA ACCTGACCCA GGAGGAGACA GGGCTCAGCT CAGACATCCT GAGCTATTAT 
CTCCTCTGCA ACCGGGCCGT CTCCAACCCC TTCCAACAGA GGCTGACTCT GTCCCAGCGA 
GCTCTGGCCA ACATCCACTC CCAGCTGCTG GGCCTGGAGC GAGAAGCTGT GCCTCAGTTC 
CCTTCAGCGC AGAAGCCTCT GCTGTCCTTG GAGGAGACTC TGAATGTGAC AGAAGGAAAT 
TTCCACCAGT TGGTGGCACT GCTACACTGC CGCAGCCTGC ACAAGGACTA TGGTGCAGCC 
CTGCGGGGCC TGTGCGAAGA CGCCCTGGAA GGCCTGCTCT TCCTGCTACT CTTCTCCCTG 
CTGTCTGCAG GAGCGCTGGC CACTGCCCTC TGCAGCCTGC CCCGAGCCTG GGCCCTCTTC 
CCACCCAGTG ACGACTACGA TGACACAGAC GATGACGACC CTTTCAACCC TCAGCAGGAA 
TCCAAGCGCT TTGTGCAGTG GCAGTCGTCT ATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001188390.1
CDS	123..1478
Translation	MGAPPGYRPSAWVHLLHQLPRADFQLRPVPSVFAPQEQEYQQALLLVAALAGLGLGLSLIFIAVYLIRFCCCRPPEPPGSKIPSPGGGCVTWSCIVALLAGCTGIGIGFYGNSETSDGVSQLSSALLHANHTLSTIDHLVLETVERLGEAVRTELTTLEEVLEPRTELVAAARGARRQAEAAAQQLQGLAFWQGVPLSPLQVAENVSFVEEYRWLAYVLLLLLELLVCLFTLLGLAKQSKWLVIVMTVMSLLVLVLSWGSMGLEAATAVGLSDFCSNPDPYVLNLTQEETGLSSDILSYYLLCNRAVSNPFQQRLTLSQRALANIHSQLLGLEREAVPQFPSAQKPLLSLEETLNVTEGNFHQLVALLHCRSLHKDYGAALRGLCEDALEGLLFLLLFSLLSAGALATALCSLPRAWALFPPSDDYDDTDDDDPFNPQQESKRFVQWQSSI

Target ORF information:

RefSeq Version	NM_001201461.1
Organism	Homo sapiens(human)
Definition	Homo sapiens tweety family member 1 (TTYH1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001201461.1

ORF Insert Sequence:

ATGGGGGCGC CCCCGGGCTA CCGGCCCTCA GCTTGGGTGC ATCTCCTCCA CCAGCTGCCC 
CGCGCCGACT TCCAGCTCCG CCCGGTGCCC AGCGTTTTCG CGCCCCAAGA GCAGGAATAC 
CAGCAGGCCT TGTTGCTGGT GGCGGCCTTG GCGGGCCTGG GCTTGGGCCT GAGCCTCATT 
TTCATCGCTG TCTACCTCAT CCGCTTCTGC TGCTGCCGGC CCCCCGAGCC CCCCGGGTCC 
AAGATCCCCT CGCCCGGGGG AGGCTGCGTC ACCTGGAGCT GCATTGTCGC CCTTCTCGCC 
GGCTGCACTG GCATTGGCAT CGGTTTCTAT GGCAACAGTG AGACCAGTGA TGGGGTGTCC 
CAGCTCAGCT CTGCGCTGCT GCACGCCAAC CACACACTCA GCACCATTGA CCACCTGGTG 
TTGGAGACGG TGGAGAGGCT GGGCGAGGCG GTGAGGACAG AGCTGACCAC CCTGGAGGAG 
GTGCTCGAGC CGCGCACGGA GCTGGTGGCT GCCGCCCGAG GGGCTCGACG GCAGGCGGAG 
GCTGCGGCCC AGCAGCTGCA GGGGCTGGCC TTCTGGCAGG GAGTGCCCCT GAGCCCCCTG 
CAGGTGGCTG AAAATGTGTC CTTTGTGGAG GAGTACAGGT GGCTGGCCTA CGTCCTCCTG 
CTGCTCCTGG AGCTGCTGGT CTGCCTCTTC ACCCTCCTGG GCCTGGCGAA GCAGAGCAAG 
TGGCTGGTGA TCGTGATGAC AGTCATGAGT CTCCTGGTTC TCGTCCTGAG CTGGGGCTCC 
ATGGGCCTGG AGGCAGCCAC GGCCGTGGGC CTCAGTGACT TCTGCTCCAA TCCAGACCCT 
TATGTTCTGA ACCTGACCCA GGAGGAGACA GGGCTCAGCT CAGACATCCT GAGCTATTAT 
CTCCTCTGCA ACCGGGCCGT CTCCAACCCC TTCCAACAGA GGCTGACTCT GTCCCAGCGA 
GCTCTGGCCA ACATCCACTC CCAGCTGCTG GGCCTGGAGC GAGAAGCTGT GCCTCAGTTC 
CCTTCAGCGC AGAAGCCTCT GCTGTCCTTG GAGGAGACTC TGAATGTGAC AGAAGGAAAT 
TTCCACCAGT TGGTGGCACT GCTACACTGC CGCAGCCTGC ACAAGGACTA TGGTGCAGCC 
CTGCGGGGCC TGTGCGAAGA CGCCCTGGAA GGCCTGCTCT TCCTGCTACT CTTCTCCCTG 
CTGTCTGCAG GAGCGCTGGC CACTGCCCTC TGCAGCCTGC CCCGAGCCTG GGCCCTCTTC 
CCACCCAGTG ACGACTACGA TGACACAGAC GATGACGACC CTTTCAACCC TCAGCAGGAA 
TCCAAGCGCT TTGTGCAGTG GCAGTCGTCT ATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TTYH1 ( NM_001201461.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001188390.1 Homo sapiens tweety family member 1 (TTYH1), transcript variant 3, mRNA.

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CloneID	OHu14002
Clone ID Related Accession (Same CDS sequence)	NM_001201461.1 , NM_001201461.2
Accession Version	NM_001201461.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1356bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-28
Organism	Homo sapiens(human)
Product	protein tweety homolog 1 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AB188496.1, BU737336.1 and AC245884.3. On Jun 1, 2019 this sequence version replaced NM_001201461.1. Transcript Variant: This variant (3) uses an alternate in-frame splice junction at the 5' end of an exon and contains an alternate exon compared to variant 2, that causes a frameshift. The resulting isoform (1) has a shorter and distinct C-terminus compared to isoform 2. ##Evidence-Data-START## Transcript exon combination :: AB188496.1, SRR1803613.176626.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2145743 [ECO:0000348] ##Evidence-Data-END##

ATGGGGGCGC CCCCGGGCTA CCGGCCCTCA GCTTGGGTGC ATCTCCTCCA CCAGCTGCCC 
CGCGCCGACT TCCAGCTCCG CCCGGTGCCC AGCGTTTTCG CGCCCCAAGA GCAGGAATAC 
CAGCAGGCCT TGTTGCTGGT GGCGGCCTTG GCGGGCCTGG GCTTGGGCCT GAGCCTCATT 
TTCATCGCTG TCTACCTCAT CCGCTTCTGC TGCTGCCGGC CCCCCGAGCC CCCCGGGTCC 
AAGATCCCCT CGCCCGGGGG AGGCTGCGTC ACCTGGAGCT GCATTGTCGC CCTTCTCGCC 
GGCTGCACTG GCATTGGCAT CGGTTTCTAT GGCAACAGTG AGACCAGTGA TGGGGTGTCC 
CAGCTCAGCT CTGCGCTGCT GCACGCCAAC CACACACTCA GCACCATTGA CCACCTGGTG 
TTGGAGACGG TGGAGAGGCT GGGCGAGGCG GTGAGGACAG AGCTGACCAC CCTGGAGGAG 
GTGCTCGAGC CGCGCACGGA GCTGGTGGCT GCCGCCCGAG GGGCTCGACG GCAGGCGGAG 
GCTGCGGCCC AGCAGCTGCA GGGGCTGGCC TTCTGGCAGG GAGTGCCCCT GAGCCCCCTG 
CAGGTGGCTG AAAATGTGTC CTTTGTGGAG GAGTACAGGT GGCTGGCCTA CGTCCTCCTG 
CTGCTCCTGG AGCTGCTGGT CTGCCTCTTC ACCCTCCTGG GCCTGGCGAA GCAGAGCAAG 
TGGCTGGTGA TCGTGATGAC AGTCATGAGT CTCCTGGTTC TCGTCCTGAG CTGGGGCTCC 
ATGGGCCTGG AGGCAGCCAC GGCCGTGGGC CTCAGTGACT TCTGCTCCAA TCCAGACCCT 
TATGTTCTGA ACCTGACCCA GGAGGAGACA GGGCTCAGCT CAGACATCCT GAGCTATTAT 
CTCCTCTGCA ACCGGGCCGT CTCCAACCCC TTCCAACAGA GGCTGACTCT GTCCCAGCGA 
GCTCTGGCCA ACATCCACTC CCAGCTGCTG GGCCTGGAGC GAGAAGCTGT GCCTCAGTTC 
CCTTCAGCGC AGAAGCCTCT GCTGTCCTTG GAGGAGACTC TGAATGTGAC AGAAGGAAAT 
TTCCACCAGT TGGTGGCACT GCTACACTGC CGCAGCCTGC ACAAGGACTA TGGTGCAGCC 
CTGCGGGGCC TGTGCGAAGA CGCCCTGGAA GGCCTGCTCT TCCTGCTACT CTTCTCCCTG 
CTGTCTGCAG GAGCGCTGGC CACTGCCCTC TGCAGCCTGC CCCGAGCCTG GGCCCTCTTC 
CCACCCAGTG ACGACTACGA TGACACAGAC GATGACGACC CTTTCAACCC TCAGCAGGAA 
TCCAAGCGCT TTGTGCAGTG GCAGTCGTCT ATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001188390.1
CDS	90..1445
Translation	MGAPPGYRPSAWVHLLHQLPRADFQLRPVPSVFAPQEQEYQQALLLVAALAGLGLGLSLIFIAVYLIRFCCCRPPEPPGSKIPSPGGGCVTWSCIVALLAGCTGIGIGFYGNSETSDGVSQLSSALLHANHTLSTIDHLVLETVERLGEAVRTELTTLEEVLEPRTELVAAARGARRQAEAAAQQLQGLAFWQGVPLSPLQVAENVSFVEEYRWLAYVLLLLLELLVCLFTLLGLAKQSKWLVIVMTVMSLLVLVLSWGSMGLEAATAVGLSDFCSNPDPYVLNLTQEETGLSSDILSYYLLCNRAVSNPFQQRLTLSQRALANIHSQLLGLEREAVPQFPSAQKPLLSLEETLNVTEGNFHQLVALLHCRSLHKDYGAALRGLCEDALEGLLFLLLFSLLSAGALATALCSLPRAWALFPPSDDYDDTDDDDPFNPQQESKRFVQWQSSI

Target ORF information:

RefSeq Version	NM_001201461.2
Organism	Homo sapiens(human)
Definition	Homo sapiens tweety family member 1 (TTYH1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001201461.2

ORF Insert Sequence:

ATGGGGGCGC CCCCGGGCTA CCGGCCCTCA GCTTGGGTGC ATCTCCTCCA CCAGCTGCCC 
CGCGCCGACT TCCAGCTCCG CCCGGTGCCC AGCGTTTTCG CGCCCCAAGA GCAGGAATAC 
CAGCAGGCCT TGTTGCTGGT GGCGGCCTTG GCGGGCCTGG GCTTGGGCCT GAGCCTCATT 
TTCATCGCTG TCTACCTCAT CCGCTTCTGC TGCTGCCGGC CCCCCGAGCC CCCCGGGTCC 
AAGATCCCCT CGCCCGGGGG AGGCTGCGTC ACCTGGAGCT GCATTGTCGC CCTTCTCGCC 
GGCTGCACTG GCATTGGCAT CGGTTTCTAT GGCAACAGTG AGACCAGTGA TGGGGTGTCC 
CAGCTCAGCT CTGCGCTGCT GCACGCCAAC CACACACTCA GCACCATTGA CCACCTGGTG 
TTGGAGACGG TGGAGAGGCT GGGCGAGGCG GTGAGGACAG AGCTGACCAC CCTGGAGGAG 
GTGCTCGAGC CGCGCACGGA GCTGGTGGCT GCCGCCCGAG GGGCTCGACG GCAGGCGGAG 
GCTGCGGCCC AGCAGCTGCA GGGGCTGGCC TTCTGGCAGG GAGTGCCCCT GAGCCCCCTG 
CAGGTGGCTG AAAATGTGTC CTTTGTGGAG GAGTACAGGT GGCTGGCCTA CGTCCTCCTG 
CTGCTCCTGG AGCTGCTGGT CTGCCTCTTC ACCCTCCTGG GCCTGGCGAA GCAGAGCAAG 
TGGCTGGTGA TCGTGATGAC AGTCATGAGT CTCCTGGTTC TCGTCCTGAG CTGGGGCTCC 
ATGGGCCTGG AGGCAGCCAC GGCCGTGGGC CTCAGTGACT TCTGCTCCAA TCCAGACCCT 
TATGTTCTGA ACCTGACCCA GGAGGAGACA GGGCTCAGCT CAGACATCCT GAGCTATTAT 
CTCCTCTGCA ACCGGGCCGT CTCCAACCCC TTCCAACAGA GGCTGACTCT GTCCCAGCGA 
GCTCTGGCCA ACATCCACTC CCAGCTGCTG GGCCTGGAGC GAGAAGCTGT GCCTCAGTTC 
CCTTCAGCGC AGAAGCCTCT GCTGTCCTTG GAGGAGACTC TGAATGTGAC AGAAGGAAAT 
TTCCACCAGT TGGTGGCACT GCTACACTGC CGCAGCCTGC ACAAGGACTA TGGTGCAGCC 
CTGCGGGGCC TGTGCGAAGA CGCCCTGGAA GGCCTGCTCT TCCTGCTACT CTTCTCCCTG 
CTGTCTGCAG GAGCGCTGGC CACTGCCCTC TGCAGCCTGC CCCGAGCCTG GGCCCTCTTC 
CCACCCAGTG ACGACTACGA TGACACAGAC GATGACGACC CTTTCAACCC TCAGCAGGAA 
TCCAAGCGCT TTGTGCAGTG GCAGTCGTCT ATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TTYH1 ( XM_017027025.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016882514.1 Homo sapiens tweety family member 1 (TTYH1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu70429
Clone ID Related Accession (Same CDS sequence)	XM_017027025.1
Accession Version	XM_017027025.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1128bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-03-25
Organism	Homo sapiens(human)
Product	protein tweety homolog 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Homo sapiens Annotation Release 109 Annotation Version :: 109 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGAAAG TGAGGCTCTG GAGAGGAAGT GAATCAAGGG CAGCCATCTG CACTGGCATT 
GGCATCGGTT TCTATGGCAA CAGTGAGACC AGTGATGGGG TGTCCCAGCT CAGCTCTGCG 
CTGCTGCACG CCAACCACAC ACTCAGCACC ATTGACCACC TGGTGTTGGA GACGGTGGAG 
AGGCTGGGCG AGGCGGTGAG GACAGAGCTG ACCACCCTGG AGGAGGTGCT CGAGCCGCGC 
ACGGAGCTGG TGGCTGCCGC CCGAGGGGCT CGACGGCAGG CGGAGGCTGC GGCCCAGCAG 
CTGCAGGGGC TGGCCTTCTG GCAGGGAGTG CCCCTGAGCC CCCTGCAGGT GGCTGAAAAT 
GTGTCCTTTG TGGAGGAGTA CAGGTGGCTG GCCTACGTCC TCCTGCTGCT CCTGGAGCTG 
CTGGTCTGCC TCTTCACCCT CCTGGGCCTG GCGAAGCAGA GCAAGTGGCT GGTGATCGTG 
ATGACAGTCA TGAGTCTCCT GGTTCTCGTC CTGAGCTGGG GCTCCATGGG CCTGGAGGCA 
GCCACGGCCG TGGGCCTCAG TGACTTCTGC TCCAATCCAG ACCCTTATGT TCTGAACCTG 
ACCCAGGAGG AGACAGGGCT CAGCTCAGAC ATCCTGAGCT ATTATCTCCT CTGCAACCGG 
GCCGTCTCCA ACCCCTTCCA ACAGAGGCTG ACTCTGTCCC AGCGAGCTCT GGCCAACATC 
CACTCCCAGC TGCTGGGCCT GGAGCGAGAA GCTGTGCCTC AGTTCCCTTC AGCGCAGAAG 
CCTCTGCTGT CCTTGGAGGA GACTCTGAAT GTGACAGAAG GAAATTTCCA CCAGTTGGTG 
GCACTGCTAC ACTGCCGCAG CCTGCACAAG GACTATGGTG CAGCCCTGCG GGGCCTGTGC 
GAAGACGCCC TGGAAGGCCT GCTCTTCCTG CTACTCTTCT CCCTGCTGTC TGCAGGAGCG 
CTGGCCACTG CCCTCTGCAG CCTGCCCCGA GCCTGGGCCC TCTTCCCACC CAGGAATCCA 
AGCGCTTTGT GCAGTGGCAG TCGTCTATCT GAGCCCCTCC TCCCGGCTGG ACTGGAGCCT 
GGCTCCCCTC TTCGTTCCTT CCCTGGCTGC CGGAGGAGAC CCCACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016882514.1
CDS	222..1349
Translation	MEKVRLWRGSESRAAICTGIGIGFYGNSETSDGVSQLSSALLHANHTLSTIDHLVLETVERLGEAVRTELTTLEEVLEPRTELVAAARGARRQAEAAAQQLQGLAFWQGVPLSPLQVAENVSFVEEYRWLAYVLLLLLELLVCLFTLLGLAKQSKWLVIVMTVMSLLVLVLSWGSMGLEAATAVGLSDFCSNPDPYVLNLTQEETGLSSDILSYYLLCNRAVSNPFQQRLTLSQRALANIHSQLLGLEREAVPQFPSAQKPLLSLEETLNVTEGNFHQLVALLHCRSLHKDYGAALRGLCEDALEGLLFLLLFSLLSAGALATALCSLPRAWALFPPRNPSALCSGSRLSEPLLPAGLEPGSPLRSFPGCRRRPH

Target ORF information:

RefSeq Version	XM_017027025.1
Organism	Homo sapiens(human)
Definition	Homo sapiens tweety family member 1 (TTYH1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017027025.1

ORF Insert Sequence:

ATGGAGAAAG TGAGGCTCTG GAGAGGAAGT GAATCAAGGG CAGCCATCTG CACTGGCATT 
GGCATCGGTT TCTATGGCAA CAGTGAGACC AGTGATGGGG TGTCCCAGCT CAGCTCTGCG 
CTGCTGCACG CCAACCACAC ACTCAGCACC ATTGACCACC TGGTGTTGGA GACGGTGGAG 
AGGCTGGGCG AGGCGGTGAG GACAGAGCTG ACCACCCTGG AGGAGGTGCT CGAGCCGCGC 
ACGGAGCTGG TGGCTGCCGC CCGAGGGGCT CGACGGCAGG CGGAGGCTGC GGCCCAGCAG 
CTGCAGGGGC TGGCCTTCTG GCAGGGAGTG CCCCTGAGCC CCCTGCAGGT GGCTGAAAAT 
GTGTCCTTTG TGGAGGAGTA CAGGTGGCTG GCCTACGTCC TCCTGCTGCT CCTGGAGCTG 
CTGGTCTGCC TCTTCACCCT CCTGGGCCTG GCGAAGCAGA GCAAGTGGCT GGTGATCGTG 
ATGACAGTCA TGAGTCTCCT GGTTCTCGTC CTGAGCTGGG GCTCCATGGG CCTGGAGGCA 
GCCACGGCCG TGGGCCTCAG TGACTTCTGC TCCAATCCAG ACCCTTATGT TCTGAACCTG 
ACCCAGGAGG AGACAGGGCT CAGCTCAGAC ATCCTGAGCT ATTATCTCCT CTGCAACCGG 
GCCGTCTCCA ACCCCTTCCA ACAGAGGCTG ACTCTGTCCC AGCGAGCTCT GGCCAACATC 
CACTCCCAGC TGCTGGGCCT GGAGCGAGAA GCTGTGCCTC AGTTCCCTTC AGCGCAGAAG 
CCTCTGCTGT CCTTGGAGGA GACTCTGAAT GTGACAGAAG GAAATTTCCA CCAGTTGGTG 
GCACTGCTAC ACTGCCGCAG CCTGCACAAG GACTATGGTG CAGCCCTGCG GGGCCTGTGC 
GAAGACGCCC TGGAAGGCCT GCTCTTCCTG CTACTCTTCT CCCTGCTGTC TGCAGGAGCG 
CTGGCCACTG CCCTCTGCAG CCTGCCCCGA GCCTGGGCCC TCTTCCCACC CAGGAATCCA 
AGCGCTTTGT GCAGTGGCAG TCGTCTATCT GAGCCCCTCC TCCCGGCTGG ACTGGAGCCT 
GGCTCCCCTC TTCGTTCCTT CCCTGGCTGC CGGAGGAGAC CCCACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TTYH1 ( XM_017027026.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016882515.1 Homo sapiens tweety family member 1 (TTYH1), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu88589
Clone ID Related Accession (Same CDS sequence)	XM_017027026.1
Accession Version	XM_017027026.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1098bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-03-25
Organism	Homo sapiens(human)
Product	protein tweety homolog 1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Homo sapiens Annotation Release 109 Annotation Version :: 109 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGAAAG TGAGGCTCTG GAGAGGAAGT GAATCAAGGG CAGCCATCTG CACTGGCATT 
GGCATCGGTT TCTATGGCAA CAGTGAGACC AGTGATGGGG TGTCCCAGCT CAGCTCTGCG 
CTGCTGCACG CCAACCACAC ACTCAGCACC ATTGACCACC TGGTGTTGGA GACGGTGGAG 
AGGCTGGGCG AGGCGGTGAG GACAGAGCTG ACCACCCTGG AGGAGGTGCT CGAGCCGCGC 
ACGGAGCTGG TGGCTGCCGC CCGAGGGGCT CGACGGCAGG CGGAGGCTGC GGCCCAGCAG 
CTGCAGGGGC TGGCCTTCTG GCAGGGAGTG CCCCTGAGCC CCCTGCAGGT GGCTGAAAAT 
GTGTCCTTTG TGGAGGAGTA CAGGTGGCTG GCCTACGTCC TCCTGCTGCT CCTGGAGCTG 
CTGGTCTGCC TCTTCACCCT CCTGGGCCTG GCGAAGCAGA GCAAGTGGCT GGTGATCGTG 
ATGACAGTCA TGAGTCTCCT GGTTCTCGTC CTGAGCTGGG GCTCCATGGG CCTGGAGGCA 
GCCACGGCCG TGGGCCTCAG TGACTTCTGC TCCAATCCAG ACCCTTATGT TCTGAACCTG 
ACCCAGGAGG AGACAGGGCT CAGCTCAGAC ATCCTGAGCT ATTATCTCCT CTGCAACCGG 
GCCGTCTCCA ACCCCTTCCA ACAGAGGCTG ACTCTGTCCC AGCGAGCTCT GGCCAACATC 
CACTCCCAGC TGCTGGGCCT GGAGCGAGAA GCTGTGCCTC AGTTCCCTTC AGCGCAGAAG 
CCTCTGCTGT CCTTGGAGGA GACTCTGAAT GTGACAGAAG GAAATTTCCA CCAGTTGGTG 
GCACTGCTAC ACTGCCGCAG CCTGCACAAG GACTATGGTG CAGCCCTGCG GGGCCTGTGC 
GAAGACGCCC TGGAAGGCCT GCTCTTCCTG CTACTCTTCT CCCTGCTGTC TGCAGGAGCG 
CTGGCCACTG CCCTCTGCAG CCTGCCCCGA GCCTGGGCCC TCTTCCCACC CAGTGACGAC 
TACGATGACA CAGACGATGA CGACCCTTTC AACCCTCAGG AATCCAAGCG CTTTGTGCAG 
TGGCAGTCGT CTATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016882515.1
CDS	222..1319
Translation	MEKVRLWRGSESRAAICTGIGIGFYGNSETSDGVSQLSSALLHANHTLSTIDHLVLETVERLGEAVRTELTTLEEVLEPRTELVAAARGARRQAEAAAQQLQGLAFWQGVPLSPLQVAENVSFVEEYRWLAYVLLLLLELLVCLFTLLGLAKQSKWLVIVMTVMSLLVLVLSWGSMGLEAATAVGLSDFCSNPDPYVLNLTQEETGLSSDILSYYLLCNRAVSNPFQQRLTLSQRALANIHSQLLGLEREAVPQFPSAQKPLLSLEETLNVTEGNFHQLVALLHCRSLHKDYGAALRGLCEDALEGLLFLLLFSLLSAGALATALCSLPRAWALFPPSDDYDDTDDDDPFNPQESKRFVQWQSSI

Target ORF information:

RefSeq Version	XM_017027026.1
Organism	Homo sapiens(human)
Definition	Homo sapiens tweety family member 1 (TTYH1), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017027026.1

ORF Insert Sequence:

ATGGAGAAAG TGAGGCTCTG GAGAGGAAGT GAATCAAGGG CAGCCATCTG CACTGGCATT 
GGCATCGGTT TCTATGGCAA CAGTGAGACC AGTGATGGGG TGTCCCAGCT CAGCTCTGCG 
CTGCTGCACG CCAACCACAC ACTCAGCACC ATTGACCACC TGGTGTTGGA GACGGTGGAG 
AGGCTGGGCG AGGCGGTGAG GACAGAGCTG ACCACCCTGG AGGAGGTGCT CGAGCCGCGC 
ACGGAGCTGG TGGCTGCCGC CCGAGGGGCT CGACGGCAGG CGGAGGCTGC GGCCCAGCAG 
CTGCAGGGGC TGGCCTTCTG GCAGGGAGTG CCCCTGAGCC CCCTGCAGGT GGCTGAAAAT 
GTGTCCTTTG TGGAGGAGTA CAGGTGGCTG GCCTACGTCC TCCTGCTGCT CCTGGAGCTG 
CTGGTCTGCC TCTTCACCCT CCTGGGCCTG GCGAAGCAGA GCAAGTGGCT GGTGATCGTG 
ATGACAGTCA TGAGTCTCCT GGTTCTCGTC CTGAGCTGGG GCTCCATGGG CCTGGAGGCA 
GCCACGGCCG TGGGCCTCAG TGACTTCTGC TCCAATCCAG ACCCTTATGT TCTGAACCTG 
ACCCAGGAGG AGACAGGGCT CAGCTCAGAC ATCCTGAGCT ATTATCTCCT CTGCAACCGG 
GCCGTCTCCA ACCCCTTCCA ACAGAGGCTG ACTCTGTCCC AGCGAGCTCT GGCCAACATC 
CACTCCCAGC TGCTGGGCCT GGAGCGAGAA GCTGTGCCTC AGTTCCCTTC AGCGCAGAAG 
CCTCTGCTGT CCTTGGAGGA GACTCTGAAT GTGACAGAAG GAAATTTCCA CCAGTTGGTG 
GCACTGCTAC ACTGCCGCAG CCTGCACAAG GACTATGGTG CAGCCCTGCG GGGCCTGTGC 
GAAGACGCCC TGGAAGGCCT GCTCTTCCTG CTACTCTTCT CCCTGCTGTC TGCAGGAGCG 
CTGGCCACTG CCCTCTGCAG CCTGCCCCGA GCCTGGGCCC TCTTCCCACC CAGTGACGAC 
TACGATGACA CAGACGATGA CGACCCTTTC AACCCTCAGG AATCCAAGCG CTTTGTGCAG 
TGGCAGTCGT CTATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Tweety-Homolog 1 Drives Brain Colonization of Gliomas.
The Journal of neuroscience : the official journal of the Society for Neuroscience37(29)6837-6850(2017 Jul)
Jung E,Osswald M,Blaes J,Wiestler B,Sahm F,Schmenger T,Solecki G,Deumelandt K,Kurz FT,Xie R,Weil S,Heil O,Thom? C,G?mmel M,Syed M,H?ring P,Huber PE,Heiland S,Platten M,von Deimling A,Wick W,Winkler F

Systematic protein-protein interaction mapping for clinically relevant human GPCRs.
Molecular systems biology13(3)918(2017 03)
Sokolina K,Kittanakom S,Snider J,Kotlyar M,Maurice P,Gand?a J,Benleulmi-Chaachoua A,Tadagaki K,Oishi A,Wong V,Malty RH,Deineko V,Aoki H,Amin S,Yao Z,Morat? X,Otasek D,Kobayashi H,Menendez J,Auerbach D,Angers S,Pr?ulj N,Bouvier M,Babu M,Ciruela F,Jockers R,Jurisica I,Stagljar I

Validation of analytical breast cancer microarray analysis in medical laboratory.
Medical oncology (Northwood, London, England)31(10)201(2014 Oct)
Darweesh AS,Louka ML,Hana M,Rashad S,El-Shinawi M,Sharaf-Eldin A,Kassim SK

Fusion of TTYH1 with the C19MC microRNA cluster drives expression of a brain-specific DNMT3B isoform in the embryonal brain tumor ETMR.
Nature genetics46(1)39-44(2014 Jan)
Kleinman CL,Gerges N,Papillon-Cavanagh S,Sin-Chan P,Pramatarova A,Quang DA,Adoue V,Busche S,Caron M,Djambazian H,Bemmo A,Fontebasso AM,Spence T,Schwartzentruber J,Albrecht S,Hauser P,Garami M,Klekner A,Bognar L,Montes JL,Staffa A,Montpetit A,Berube P,Zakrzewska M,Zakrzewski K,Liberski PP,Dong Z,Siegel PM,Duchaine T,Perotti C,Fleming A,Faury D,Remke M,Gallo M,Dirks P,Taylor MD,Sladek R,Pastinen T,Chan JA,Huang A,Majewski J,Jabado N

Genome-wide association study identifies loci affecting blood copper, selenium and zinc.
Human molecular genetics22(19)3998-4006(2013 Oct)
Evans DM,Zhu G,Dy V,Heath AC,Madden PA,Kemp JP,McMahon G,St Pourcain B,Timpson NJ,Golding J,Lawlor DA,Steer C,Montgomery GW,Martin NG,Smith GD,Whitfield JB

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TTYH1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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