VN1R1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	VN1R1
Entrez Gene ID	57191
Full Name	vomeronasal 1 receptor 1
Synonyms	V1RL1,VNR19I1,ZVNH1,ZVNR1
General protein information	Preferred Names vomeronasal 1 receptor 1 Names vomeronasal type-1 receptor 1 G-protein coupled receptor GPCR24 V1R-like 1 V1r-like receptor 1 V3r-related gene protein hGPCR24 vomeronasal olfactory receptor chromosome 19 subtype I member 1 vomeronasal olfactory receptor, (chromosome 19) subtype I, member 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19q13.43
Summary	Pheromones are chemical signals that elicit specific behavioral responses and physiologic alterations in recipients of the same species. The protein encoded by this gene is similar to pheromone receptors and is primarily localized to the olfactory mucosa. An alternate splice variant of this gene is thought to exist, but its full length nature has not been determined. [provided by RefSeq, Jul 2008].
Disorder MIM:	605234

mRNA and Protein(s)

mRNA	Protein	Name
NM_020633.3	NP_065684.1	vomeronasal type-1 receptor 1

Pathways from BioSystems

Homologies

Bos taurus (cattle)	VN1R1	XP_005219876.1
Rattus norvegicus (Norway rat)	Vom1r53	NP_001008934.1
Homo sapiens (human)	VN1R1	NP_065684.1
Rattus norvegicus (Norway rat)	Vom1r52	NP_001008930.1
Rattus norvegicus (Norway rat)	Vom1r54	NP_001008963.1
Rattus norvegicus (Norway rat)	Vom1r51	NP_001008933.1

Gene Ontology
Bibliography

Related articles in PubMed

A missense polymorphism in the putative pheromone receptor gene VN1R1 is associated with sociosexual behavior.
Henningsson S, Hovey D, Vass K, Walum H, Sandnabba K, Santtila P, Jern P, Westberg L
Translational psychiatry7(4)e1102(2017 04)

Structure and function analyses of the purified GPCR human vomeronasal type 1 receptor 1.
Corin K, Baaske P, Geissler S, Wienken CJ, Duhr S, Braun D, Zhang S
Scientific reports1172(2011)

Extreme variability among mammalian V1R gene families.
Young JM, Massa HF, Hsu L, Trask BJ
Genome research20(1)10-8(2010 Jan)

Association study of human VN1R1 pheromone receptor gene alleles and gender.
Mitropoulos C, Papachatzopoulou A, Menounos PG, Kolonelou C, Pappa M, Bertolis G, Gerou S, Patrinos GP
Genetic testing11(2)128-32(2007)

Evolutionary deterioration of the vomeronasal pheromone transduction pathway in catarrhine primates.
Zhang J, Webb DM
Proceedings of the National Academy of Sciences of the United States of America100(14)8337-41(2003 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

the reported association in this study suggests that, as a result of genetic variation, naturally occurring endogenous modulation of VN1R1 function affects women's socio-sexual behavior, and that humans thus communicate via chemo-signaling.
Title: A missense polymorphism in the putative pheromone receptor gene VN1R1 is associated with sociosexual behavior.

Structure and function analyses of the purified GPCR human vomeronasal type 1 receptor 1
Title: Structure and function analyses of the purified GPCR human vomeronasal type 1 receptor 1.

Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.

The human VN1R1 gene are unlikely to be associated with gender and hence to contribute to distinct gender-specific behavior.
Title: Association study of human VN1R1 pheromone receptor gene alleles and gender.

The following VN1R1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the VN1R1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu12201	NM_020633.3 Latest version!	Homo sapiens vomeronasal 1 receptor 1 (VN1R1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

VN1R1 ( NM_020633.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_065684.1 Homo sapiens vomeronasal 1 receptor 1 (VN1R1), mRNA.

Price & Availability↑

CloneID	OHu12201
Clone ID Related Accession (Same CDS sequence)	NM_020633.3
Accession Version	NM_020633.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1062bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Homo sapiens(human)
Product	vomeronasal type-1 receptor 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC004076.1 and BC095508.1. On Jan 6, 2011 this sequence version replaced NM_020633.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGGTTGGAG ACACATTAAA ACTTCTGTCT CCACTGATGA CAAGATACTT CTTTCTGCTT 
TTTTATTCTA CTGATTCTTC AGACCTCAAT GAAAATCAAC ATCCCCTAGA TTTTGATGAA 
ATGGCTTTTG GAAAAGTAAA ATCAGGGATT AGCTTCCTCA TTCAGACTGG AGTTGGGATC 
CTGGGAAATT CCTTTCTCCT TTGTTTTTAT AACTTAATTT TGTTCACTGG ACACAAGCTG 
AGACCCACGG ACTTGATTCT CAGCCAACTG GCCTTGGCTA ACTCCATGGT CCTTTTCTTT 
AAAGGGATAC CTCAGACAAT GGCAGCTTTT GGATTGAAAT ATTTGCTGAA TGACACTGGA 
TGTAAGTTTG TCTTTTATTA TCACAGGGTG GGCACAAGAG TTTCCCTCAG CACCATCTGC 
CTTCTCAATG GATTCCAAGC CATTAAGCTC AACCCCAGTA TATGCAGGTG GATGGAGATC 
AAGATTAGAT CCCCAAGGTT TATTGACTTC TGTTGTCTCC TCTGCTGGGC CCCCCATGTC 
TTGATGAATG CATCTGTTCT TCTATTAGTG AATGGCCCAC TGAATAGCAA AAACAGTAGT 
GCAAAAAACA ATTATGGATA CTGTTCTTAC AAAGCATCAA AGAGATTTAG CTCATTACAT 
GCAGTCTTAT ATTTTTCCCC TGATTTTATG AGTTTGGGCT TCATGGTCTG GGCCAGTGGC 
TCCATGGTCT TCTTCCTCTA CAGACACAAG CAGCAAGTCC AACACAATCA CAGCAACAGA 
CTCTCCTGCA GACCTTCCCA GGAAGCCAGA GCCACACACA CCATCATGGT CCTGGTGAGC 
TCCTTTTTTG TTTTCTATTC AGTCCATAGT TTTCTGACAA TTTGGACAAC TGTAGTTGCA 
AACCCAGGCC AGTGGATAGT GACCAACTCT GTGTTGGTCG CCTCATGTTT CCCAGCACGC 
AGCCCTTTTG TCCTCATCAT GAGTGATACT CATATCTCTC AGTTCTGTTT TGCCTGCAGG 
ACAAGGAAAA CACTCTTTCC TAATCTGGTT GTCATGCCAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_065684.1
CDS	254..1315
Translation	MVGDTLKLLSPLMTRYFFLLFYSTDSSDLNENQHPLDFDEMAFGKVKSGISFLIQTGVGILGNSFLLCFYNLILFTGHKLRPTDLILSQLALANSMVLFFKGIPQTMAAFGLKYLLNDTGCKFVFYYHRVGTRVSLSTICLLNGFQAIKLNPSICRWMEIKIRSPRFIDFCCLLCWAPHVLMNASVLLLVNGPLNSKNSSAKNNYGYCSYKASKRFSSLHAVLYFSPDFMSLGFMVWASGSMVFFLYRHKQQVQHNHSNRLSCRPSQEARATHTIMVLVSSFFVFYSVHSFLTIWTTVVANPGQWIVTNSVLVASCFPARSPFVLIMSDTHISQFCFACRTRKTLFPNLVVMP

Target ORF information:

RefSeq Version	NM_020633.3
Organism	Homo sapiens(human)
Definition	Homo sapiens vomeronasal 1 receptor 1 (VN1R1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_020633.3

ORF Insert Sequence:

ATGGTTGGAG ACACATTAAA ACTTCTGTCT CCACTGATGA CAAGATACTT CTTTCTGCTT 
TTTTATTCTA CTGATTCTTC AGACCTCAAT GAAAATCAAC ATCCCCTAGA TTTTGATGAA 
ATGGCTTTTG GAAAAGTAAA ATCAGGGATT AGCTTCCTCA TTCAGACTGG AGTTGGGATC 
CTGGGAAATT CCTTTCTCCT TTGTTTTTAT AACTTAATTT TGTTCACTGG ACACAAGCTG 
AGACCCACGG ACTTGATTCT CAGCCAACTG GCCTTGGCTA ACTCCATGGT CCTTTTCTTT 
AAAGGGATAC CTCAGACAAT GGCAGCTTTT GGATTGAAAT ATTTGCTGAA TGACACTGGA 
TGTAAGTTTG TCTTTTATTA TCACAGGGTG GGCACAAGAG TTTCCCTCAG CACCATCTGC 
CTTCTCAATG GATTCCAAGC CATTAAGCTC AACCCCAGTA TATGCAGGTG GATGGAGATC 
AAGATTAGAT CCCCAAGGTT TATTGACTTC TGTTGTCTCC TCTGCTGGGC CCCCCATGTC 
TTGATGAATG CATCTGTTCT TCTATTAGTG AATGGCCCAC TGAATAGCAA AAACAGTAGT 
GCAAAAAACA ATTATGGATA CTGTTCTTAC AAAGCATCAA AGAGATTTAG CTCATTACAT 
GCAGTCTTAT ATTTTTCCCC TGATTTTATG AGTTTGGGCT TCATGGTCTG GGCCAGTGGC 
TCCATGGTCT TCTTCCTCTA CAGACACAAG CAGCAAGTCC AACACAATCA CAGCAACAGA 
CTCTCCTGCA GACCTTCCCA GGAAGCCAGA GCCACACACA CCATCATGGT CCTGGTGAGC 
TCCTTTTTTG TTTTCTATTC AGTCCATAGT TTTCTGACAA TTTGGACAAC TGTAGTTGCA 
AACCCAGGCC AGTGGATAGT GACCAACTCT GTGTTGGTCG CCTCATGTTT CCCAGCACGC 
AGCCCTTTTG TCCTCATCAT GAGTGATACT CATATCTCTC AGTTCTGTTT TGCCTGCAGG 
ACAAGGAAAA CACTCTTTCC TAATCTGGTT GTCATGCCAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A missense polymorphism in the putative pheromone receptor gene VN1R1 is associated with sociosexual behavior.
Translational psychiatry7(4)e1102(2017 04)
Henningsson S,Hovey D,Vass K,Walum H,Sandnabba K,Santtila P,Jern P,Westberg L

Structure and function analyses of the purified GPCR human vomeronasal type 1 receptor 1.
Scientific reports1172(2011)
Corin K,Baaske P,Geissler S,Wienken CJ,Duhr S,Braun D,Zhang S

Extreme variability among mammalian V1R gene families.
Genome research20(1)10-8(2010 Jan)
Young JM,Massa HF,Hsu L,Trask BJ

Association study of human VN1R1 pheromone receptor gene alleles and gender.
Genetic testing11(2)128-32(2007)
Mitropoulos C,Papachatzopoulou A,Menounos PG,Kolonelou C,Pappa M,Bertolis G,Gerou S,Patrinos GP

Evolutionary deterioration of the vomeronasal pheromone transduction pathway in catarrhine primates.
Proceedings of the National Academy of Sciences of the United States of America100(14)8337-41(2003 Jul)
Zhang J,Webb DM

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VN1R1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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