Gene Symbol | ZMIZ1 |
Entrez Gene ID | 57178 |
Full Name | zinc finger MIZ-type containing 1 |
Synonyms | MIZ,RAI17,TRAFIP10,ZIMP10 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a member of the PIAS (protein inhibitor of activated STAT) family of proteins. The encoded protein regulates the activity of various transcription factors, including the androgen receptor, Smad3/4, and p53. The encoded protein may also play a role in sumoylation. A translocation between this locus on chromosome 10 and the protein tyrosine kinase ABL1 locus on chromosome 9 has been associated with acute lymphoblastic leukemia. [provided by RefSeq, Mar 2010]. |
Disorder MIM: |