gRNAs
The following CORO1B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CORO1B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OHu09420 |
|
| Clone ID Related Accession (Same CDS sequence) | NM_020441.2 , NM_001018070.2 , NM_020441.3 | |
| Accession Version | NM_020441.2 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1470bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2017-10-02 | |
| Organism | Homo sapiens(human) | |
| Product | coronin-1B | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AP003419.3 and BC006449.1. On May 17, 2005 this sequence version replaced NM_020441.1. Transcript Variant: This variant (1) differs in the 5' UTR compared to variant 2. Both variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC006449.1, AK000860.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGTCCTTCC GCAAAGTGGT CCGGCAGAGC AAATTCCGGC ATGTGTTCGG GCAGCCGGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_065174.1 |
| CDS | 112..1581 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_020441.2 |
1 | ATGTCCTTCC GCAAAGTGGT CCGGCAGAGC AAATTCCGGC ATGTGTTCGG GCAGCCGGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu09420 |
|
| Clone ID Related Accession (Same CDS sequence) | NM_020441.2 , NM_001018070.2 , NM_020441.3 | |
| Accession Version | NM_001018070.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1470bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-10-09 | |
| Organism | Homo sapiens(human) | |
| Product | coronin-1B | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA061767.1 and BC006449.1. On Aug 5, 2011 this sequence version replaced NM_001018070.1. Transcript Variant: This variant (2) represents the longer transcript. Both variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.909530.1, SRR3476690.103643.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGTCCTTCC GCAAAGTGGT CCGGCAGAGC AAATTCCGGC ATGTGTTCGG GCAGCCGGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001018080.1 |
| CDS | 134..1603 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001018070.2 |
1 | ATGTCCTTCC GCAAAGTGGT CCGGCAGAGC AAATTCCGGC ATGTGTTCGG GCAGCCGGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu09420 |
|
| Clone ID Related Accession (Same CDS sequence) | NM_020441.2 , NM_001018070.2 , NM_020441.3 | |
| Accession Version | NM_020441.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1470bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-10-09 | |
| Organism | Homo sapiens(human) | |
| Product | coronin-1B | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AP003419.3 and BC006449.1. On Nov 23, 2018 this sequence version replaced NM_020441.2. Transcript Variant: This variant (1) differs in the 5' UTR compared to variant 2. Both variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.1134815.1, AK000860.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000341356.10/ ENSP00000340211.5 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length. | |
1 | ATGTCCTTCC GCAAAGTGGT CCGGCAGAGC AAATTCCGGC ATGTGTTCGG GCAGCCGGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_065174.1 |
| CDS | 76..1545 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_020441.3 |
1 | ATGTCCTTCC GCAAAGTGGT CCGGCAGAGC AAATTCCGGC ATGTGTTCGG GCAGCCGGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Binding of coronin 1B to T?RI negatively regulates the TGF?1 signaling pathway. |
Architecture of the human interactome defines protein communities and disease networks. |
Coronin 1B serine 2 phosphorylation by p38? is critical for vascular endothelial growth factor-induced migration of human umbilical vein endothelial cells. |
Coronin 1B supports RhoA signaling at cell-cell junctions through Myosin II. |
Coronin 1B Reorganizes the Architecture of F-Actin Networks for Contractility at Steady-State and Apoptotic Adherens Junctions. |
