GJC2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	GJC2
Entrez Gene ID	57165
Full Name	gap junction protein gamma 2
Synonyms	CX46.6,Cx47,GJA12,HLD2,LMPH1C,PMLDAR,SPG44
General protein information	Preferred Names gap junction protein gamma 2 Names gap junction gamma-2 protein connexin-46.6 connexin-47 gap junction alpha-12 protein gap junction protein, gamma 2, 47kDa
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1q42.13
Summary	This gene encodes a gap junction protein. Gap junction proteins are members of a large family of homologous connexins and comprise 4 transmembrane, 2 extracellular, and 3 cytoplasmic domains. This gene plays a key role in central myelination and is involved in peripheral myelination in humans. Defects in this gene are the cause of autosomal recessive Pelizaeus-Merzbacher-like disease-1. [provided by RefSeq, Jul 2008].
Disorder MIM:	608803
Disorder Html:	Leukodystrophy, hypomyelinating, 2, 608804 (3); Spastic paraplegia 44, autosomal recessive, 613206 (3); Lymphedema, hereditary, IC, 613480 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_020435.3	NP_065168.2	gap junction gamma-2 protein
NM_020435.4	NP_065168.2	gap junction gamma-2 protein

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	GJC2	XP_001145449.1
	GJC2	XP_001083576.2
Mus musculus (house mouse)	Gjc2	NP_536702.3
Homo sapiens (human)	GJC2	NP_065168.2
Canis lupus familiaris (dog)	GJC2	XP_005628409.1
Bos taurus (cattle)	GJC2	NP_001039905.1
Rattus norvegicus (Norway rat)	Gjc2	NP_001094254.1

Gene Ontology
Bibliography

Related articles in PubMed

Different Mutations of Gap Junction Connexin 47 Lead to Discrepant Activation of Unfolded Protein Response Pathway in Pelizaeus-Merzbacher-Like Disease.
Chen N, Wang J, Jiang Y, Wu Y, Hao H, Ji T
Neuropediatrics48(6)426-431(2017 12)

GJC2 promoter mutations causing Pelizaeus-Merzbacher-like disease.
Gotoh L, Inoue K, Helman G, Mora S, Maski K, Soul JS, Bloom M, Evans SH, Goto YI, Caldovic L, Hobson GM, Vanderver A
Molecular genetics and metabolism111(3)393-398(2014 03)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

GJC2 promoter region mutation screening should be included in the evaluation of patients with unexplained hypomyelinating leukodystrophies.
Title: GJC2 promoter mutations causing Pelizaeus-Merzbacher-like disease.

we provide evidence that a mutation in GJA1 leads not only to ODD as already described in the literature, but can also lead to lymphoedema as an associated feature.
Title: A novel mutation in GJA1 causing oculodentodigital syndrome and primary lymphoedema in a three generation family.

a novel homozygous mutation in GJC2 was identified in a 21-year-old female patient with Pelizaeus-Merzbacher-like disease
Title: A novel homozygous mutation of GJC2 derived from maternal uniparental disomy in a female patient with Pelizaeus-Merzbacher-like disease.

Most of the Pelizaeus-Merzbacher-like disease (PMLD)-linked Cx47 mutants disrupt Cx47/Cx47 and Cx47/Cx43 GJ function in the glial network, which may play a role in leading to PMLD symptoms
Title: The distribution and functional properties of Pelizaeus-Merzbacher-like disease-linked Cx47 mutations on Cx47/Cx47 homotypic and Cx47/Cx43 heterotypic gap junctions.

founder mutation c.-167A>G localized in the GJC2 protein promoter region in patients with Pelizaeus Merzbacher disease and Pelizaeus Merzbacher like disease
Title: Molecular confirmation of founder mutation c.-167A>G in Tunisian patients with PMLD disease.

The following GJC2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GJC2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu22131	NM_020435.4 Latest version!	Homo sapiens gap junction protein gamma 2 (GJC2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
View Old Accession Versions >>
OHu22131	NM_020435.3	Homo sapiens gap junction protein gamma 2 (GJC2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

GJC2 ( NM_020435.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_065168.2 Homo sapiens gap junction protein gamma 2 (GJC2), mRNA.

Price & Availability↑

CloneID	OHu22131
Clone ID Related Accession (Same CDS sequence)	NM_020435.3 , NM_020435.4
Accession Version	NM_020435.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1320bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	gap junction gamma-2 protein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC089439.1 and AL359510.24. This sequence is a reference standard in the RefSeqGene project. On Jun 4, 2011 this sequence version replaced NM_020435.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC089439.1, BC035840.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA2145240 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACCAACA TGAGCTGGAG CTTCCTGACG CGGCTGCTGG AGGAGATCCA CAACCACTCC 
ACCTTCGTGG GCAAGGTGTG GCTCACGGTG CTGGTGGTCT TCCGCATCGT GCTGACGGCT 
GTGGGCGGCG AGGCCATCTA CTCGGACGAG CAGGCCAAGT TCACTTGCAA CACGCGGCAG 
CCAGGCTGCG ACAACGTCTG CTATGACGCC TTCGCGCCCC TGTCGCACGT GCGCTTCTGG 
GTCTTCCAGA TTGTGGTCAT CTCCACGCCC TCGGTCATGT ACCTGGGCTA CGCCGTGCAC 
CGCCTGGCCC GTGCGTCTGA GCAGGAGCGG CGCCGCGCCC TCCGCCGCCG CCCGGGGCCA 
CGCCGCGCGC CCCGAGCGCA CCTGCCGCCC CCGCACGCCG GCTGGCCTGA GCCCGCCGAC 
CTGGGCGAGG AGGAGCCCAT GCTGGGCCTG GGCGAGGAGG AGGAGGAGGA GGAGACGGGG 
GCAGCCGAGG GCGCCGGCGA GGAAGCGGAG GAGGCAGGCG CGGAGGAGGC GTGCACTAAG 
GCGGTCGGCG CTGACGGCAA GGCGGCAGGG ACCCCGGGCC CGACCGGGCA ACACGATGGG 
CGGAGGCGCA TCCAGCGGGA GGGCCTGATG CGCGTGTACG TGGCCCAGCT GGTGGCCAGG 
GCAGCTTTCG AGGTGGCCTT CCTGGTGGGC CAGTACCTGC TGTACGGCTT CGAGGTGCGA 
CCGTTCTTTC CCTGCAGCCG CCAGCCCTGC CCGCACGTGG TGGACTGCTT CGTGTCGCGC 
CCTACTGAAA AGACGGTCTT CCTGCTGGTT ATGTACGTGG TCAGCTGCCT GTGCCTGCTG 
CTCAACCTCT GTGAGATGGC CCACCTGGGC TTGGGCAGCG CGCAGGACGC GGTGCGCGGC 
CGCCGCGGCC CCCCGGCCTC CGCCCCCGCC CCCGCGCCGC GGCCCCCGCC CTGCGCCTTC 
CCTGCGGCGG CCGCTGGCTT GGCCTGCCCG CCCGACTACA GCCTGGTGGT GCGGGCGGCC 
GAGCGCGCTC GGGCGCATGA CCAGAACCTG GCAAACCTGG CCCTGCAGGC GCTGCGCGAC 
GGGGCAGCGG CTGGGGACCG CGACCGGGAC AGTTCGCCGT GCGTCGGCCT CCCTGCGGCC 
TCCCGGGGGC CCCCCAGAGC AGGCGCCCCC GCGTCCCGGA CGGGCAGTGC TACCTCTGCG 
GGCACTGTCG GGGAGCAGGG CCGGCCCGGC ACCCACGAGC GGCCAGGAGC CAAGCCCAGG 
GCTGGCTCCG AGAAGGGCAG TGCCAGCAGC AGGGACGGGA AGACCACCGT GTGGATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_065168.2
CDS	314..1633
Translation	MTNMSWSFLTRLLEEIHNHSTFVGKVWLTVLVVFRIVLTAVGGEAIYSDEQAKFTCNTRQPGCDNVCYDAFAPLSHVRFWVFQIVVISTPSVMYLGYAVHRLARASEQERRRALRRRPGPRRAPRAHLPPPHAGWPEPADLGEEEPMLGLGEEEEEEETGAAEGAGEEAEEAGAEEACTKAVGADGKAAGTPGPTGQHDGRRRIQREGLMRVYVAQLVARAAFEVAFLVGQYLLYGFEVRPFFPCSRQPCPHVVDCFVSRPTEKTVFLLVMYVVSCLCLLLNLCEMAHLGLGSAQDAVRGRRGPPASAPAPAPRPPPCAFPAAAAGLACPPDYSLVVRAAERARAHDQNLANLALQALRDGAAAGDRDRDSSPCVGLPAASRGPPRAGAPASRTGSATSAGTVGEQGRPGTHERPGAKPRAGSEKGSASSRDGKTTVWI

Target ORF information:

RefSeq Version	NM_020435.3
Organism	Homo sapiens(human)
Definition	Homo sapiens gap junction protein gamma 2 (GJC2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_020435.3

ORF Insert Sequence:

ATGACCAACA TGAGCTGGAG CTTCCTGACG CGGCTGCTGG AGGAGATCCA CAACCACTCC 
ACCTTCGTGG GCAAGGTGTG GCTCACGGTG CTGGTGGTCT TCCGCATCGT GCTGACGGCT 
GTGGGCGGCG AGGCCATCTA CTCGGACGAG CAGGCCAAGT TCACTTGCAA CACGCGGCAG 
CCAGGCTGCG ACAACGTCTG CTATGACGCC TTCGCGCCCC TGTCGCACGT GCGCTTCTGG 
GTCTTCCAGA TTGTGGTCAT CTCCACGCCC TCGGTCATGT ACCTGGGCTA CGCCGTGCAC 
CGCCTGGCCC GTGCGTCTGA GCAGGAGCGG CGCCGCGCCC TCCGCCGCCG CCCGGGGCCA 
CGCCGCGCGC CCCGAGCGCA CCTGCCGCCC CCGCACGCCG GCTGGCCTGA GCCCGCCGAC 
CTGGGCGAGG AGGAGCCCAT GCTGGGCCTG GGCGAGGAGG AGGAGGAGGA GGAGACGGGG 
GCAGCCGAGG GCGCCGGCGA GGAAGCGGAG GAGGCAGGCG CGGAGGAGGC GTGCACTAAG 
GCGGTCGGCG CTGACGGCAA GGCGGCAGGG ACCCCGGGCC CGACCGGGCA ACACGATGGG 
CGGAGGCGCA TCCAGCGGGA GGGCCTGATG CGCGTGTACG TGGCCCAGCT GGTGGCCAGG 
GCAGCTTTCG AGGTGGCCTT CCTGGTGGGC CAGTACCTGC TGTACGGCTT CGAGGTGCGA 
CCGTTCTTTC CCTGCAGCCG CCAGCCCTGC CCGCACGTGG TGGACTGCTT CGTGTCGCGC 
CCTACTGAAA AGACGGTCTT CCTGCTGGTT ATGTACGTGG TCAGCTGCCT GTGCCTGCTG 
CTCAACCTCT GTGAGATGGC CCACCTGGGC TTGGGCAGCG CGCAGGACGC GGTGCGCGGC 
CGCCGCGGCC CCCCGGCCTC CGCCCCCGCC CCCGCGCCGC GGCCCCCGCC CTGCGCCTTC 
CCTGCGGCGG CCGCTGGCTT GGCCTGCCCG CCCGACTACA GCCTGGTGGT GCGGGCGGCC 
GAGCGCGCTC GGGCGCATGA CCAGAACCTG GCAAACCTGG CCCTGCAGGC GCTGCGCGAC 
GGGGCAGCGG CTGGGGACCG CGACCGGGAC AGTTCGCCGT GCGTCGGCCT CCCTGCGGCC 
TCCCGGGGGC CCCCCAGAGC AGGCGCCCCC GCGTCCCGGA CGGGCAGTGC TACCTCTGCG 
GGCACTGTCG GGGAGCAGGG CCGGCCCGGC ACCCACGAGC GGCCAGGAGC CAAGCCCAGG 
GCTGGCTCCG AGAAGGGCAG TGCCAGCAGC AGGGACGGGA AGACCACCGT GTGGATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GJC2 ( NM_020435.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_065168.2 Homo sapiens gap junction protein gamma 2 (GJC2), mRNA.

Price & Availability↑

CloneID	OHu22131
Clone ID Related Accession (Same CDS sequence)	NM_020435.3 , NM_020435.4
Accession Version	NM_020435.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1320bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-26
Organism	Homo sapiens(human)
Product	gap junction gamma-2 protein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC089439.1 and AL359510.24. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_020435.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC089439.1, BC035840.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA2145240 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000366714.3/ ENSP00000355675.2 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGACCAACA TGAGCTGGAG CTTCCTGACG CGGCTGCTGG AGGAGATCCA CAACCACTCC 
ACCTTCGTGG GCAAGGTGTG GCTCACGGTG CTGGTGGTCT TCCGCATCGT GCTGACGGCT 
GTGGGCGGCG AGGCCATCTA CTCGGACGAG CAGGCCAAGT TCACTTGCAA CACGCGGCAG 
CCAGGCTGCG ACAACGTCTG CTATGACGCC TTCGCGCCCC TGTCGCACGT GCGCTTCTGG 
GTCTTCCAGA TTGTGGTCAT CTCCACGCCC TCGGTCATGT ACCTGGGCTA CGCCGTGCAC 
CGCCTGGCCC GTGCGTCTGA GCAGGAGCGG CGCCGCGCCC TCCGCCGCCG CCCGGGGCCA 
CGCCGCGCGC CCCGAGCGCA CCTGCCGCCC CCGCACGCCG GCTGGCCTGA GCCCGCCGAC 
CTGGGCGAGG AGGAGCCCAT GCTGGGCCTG GGCGAGGAGG AGGAGGAGGA GGAGACGGGG 
GCAGCCGAGG GCGCCGGCGA GGAAGCGGAG GAGGCAGGCG CGGAGGAGGC GTGCACTAAG 
GCGGTCGGCG CTGACGGCAA GGCGGCAGGG ACCCCGGGCC CGACCGGGCA ACACGATGGG 
CGGAGGCGCA TCCAGCGGGA GGGCCTGATG CGCGTGTACG TGGCCCAGCT GGTGGCCAGG 
GCAGCTTTCG AGGTGGCCTT CCTGGTGGGC CAGTACCTGC TGTACGGCTT CGAGGTGCGA 
CCGTTCTTTC CCTGCAGCCG CCAGCCCTGC CCGCACGTGG TGGACTGCTT CGTGTCGCGC 
CCTACTGAAA AGACGGTCTT CCTGCTGGTT ATGTACGTGG TCAGCTGCCT GTGCCTGCTG 
CTCAACCTCT GTGAGATGGC CCACCTGGGC TTGGGCAGCG CGCAGGACGC GGTGCGCGGC 
CGCCGCGGCC CCCCGGCCTC CGCCCCCGCC CCCGCGCCGC GGCCCCCGCC CTGCGCCTTC 
CCTGCGGCGG CCGCTGGCTT GGCCTGCCCG CCCGACTACA GCCTGGTGGT GCGGGCGGCC 
GAGCGCGCTC GGGCGCATGA CCAGAACCTG GCAAACCTGG CCCTGCAGGC GCTGCGCGAC 
GGGGCAGCGG CTGGGGACCG CGACCGGGAC AGTTCGCCGT GCGTCGGCCT CCCTGCGGCC 
TCCCGGGGGC CCCCCAGAGC AGGCGCCCCC GCGTCCCGGA CGGGCAGTGC TACCTCTGCG 
GGCACTGTCG GGGAGCAGGG CCGGCCCGGC ACCCACGAGC GGCCAGGAGC CAAGCCCAGG 
GCTGGCTCCG AGAAGGGCAG TGCCAGCAGC AGGGACGGGA AGACCACCGT GTGGATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_065168.2
CDS	98..1417
Translation	MTNMSWSFLTRLLEEIHNHSTFVGKVWLTVLVVFRIVLTAVGGEAIYSDEQAKFTCNTRQPGCDNVCYDAFAPLSHVRFWVFQIVVISTPSVMYLGYAVHRLARASEQERRRALRRRPGPRRAPRAHLPPPHAGWPEPADLGEEEPMLGLGEEEEEEETGAAEGAGEEAEEAGAEEACTKAVGADGKAAGTPGPTGQHDGRRRIQREGLMRVYVAQLVARAAFEVAFLVGQYLLYGFEVRPFFPCSRQPCPHVVDCFVSRPTEKTVFLLVMYVVSCLCLLLNLCEMAHLGLGSAQDAVRGRRGPPASAPAPAPRPPPCAFPAAAAGLACPPDYSLVVRAAERARAHDQNLANLALQALRDGAAAGDRDRDSSPCVGLPAASRGPPRAGAPASRTGSATSAGTVGEQGRPGTHERPGAKPRAGSEKGSASSRDGKTTVWI

Target ORF information:

RefSeq Version	NM_020435.4
Organism	Homo sapiens(human)
Definition	Homo sapiens gap junction protein gamma 2 (GJC2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_020435.4

ORF Insert Sequence:

ATGACCAACA TGAGCTGGAG CTTCCTGACG CGGCTGCTGG AGGAGATCCA CAACCACTCC 
ACCTTCGTGG GCAAGGTGTG GCTCACGGTG CTGGTGGTCT TCCGCATCGT GCTGACGGCT 
GTGGGCGGCG AGGCCATCTA CTCGGACGAG CAGGCCAAGT TCACTTGCAA CACGCGGCAG 
CCAGGCTGCG ACAACGTCTG CTATGACGCC TTCGCGCCCC TGTCGCACGT GCGCTTCTGG 
GTCTTCCAGA TTGTGGTCAT CTCCACGCCC TCGGTCATGT ACCTGGGCTA CGCCGTGCAC 
CGCCTGGCCC GTGCGTCTGA GCAGGAGCGG CGCCGCGCCC TCCGCCGCCG CCCGGGGCCA 
CGCCGCGCGC CCCGAGCGCA CCTGCCGCCC CCGCACGCCG GCTGGCCTGA GCCCGCCGAC 
CTGGGCGAGG AGGAGCCCAT GCTGGGCCTG GGCGAGGAGG AGGAGGAGGA GGAGACGGGG 
GCAGCCGAGG GCGCCGGCGA GGAAGCGGAG GAGGCAGGCG CGGAGGAGGC GTGCACTAAG 
GCGGTCGGCG CTGACGGCAA GGCGGCAGGG ACCCCGGGCC CGACCGGGCA ACACGATGGG 
CGGAGGCGCA TCCAGCGGGA GGGCCTGATG CGCGTGTACG TGGCCCAGCT GGTGGCCAGG 
GCAGCTTTCG AGGTGGCCTT CCTGGTGGGC CAGTACCTGC TGTACGGCTT CGAGGTGCGA 
CCGTTCTTTC CCTGCAGCCG CCAGCCCTGC CCGCACGTGG TGGACTGCTT CGTGTCGCGC 
CCTACTGAAA AGACGGTCTT CCTGCTGGTT ATGTACGTGG TCAGCTGCCT GTGCCTGCTG 
CTCAACCTCT GTGAGATGGC CCACCTGGGC TTGGGCAGCG CGCAGGACGC GGTGCGCGGC 
CGCCGCGGCC CCCCGGCCTC CGCCCCCGCC CCCGCGCCGC GGCCCCCGCC CTGCGCCTTC 
CCTGCGGCGG CCGCTGGCTT GGCCTGCCCG CCCGACTACA GCCTGGTGGT GCGGGCGGCC 
GAGCGCGCTC GGGCGCATGA CCAGAACCTG GCAAACCTGG CCCTGCAGGC GCTGCGCGAC 
GGGGCAGCGG CTGGGGACCG CGACCGGGAC AGTTCGCCGT GCGTCGGCCT CCCTGCGGCC 
TCCCGGGGGC CCCCCAGAGC AGGCGCCCCC GCGTCCCGGA CGGGCAGTGC TACCTCTGCG 
GGCACTGTCG GGGAGCAGGG CCGGCCCGGC ACCCACGAGC GGCCAGGAGC CAAGCCCAGG 
GCTGGCTCCG AGAAGGGCAG TGCCAGCAGC AGGGACGGGA AGACCACCGT GTGGATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Different Mutations of Gap Junction Connexin 47 Lead to Discrepant Activation of Unfolded Protein Response Pathway in Pelizaeus-Merzbacher-Like Disease.
Neuropediatrics48(6)426-431(2017 12)
Chen N,Wang J,Jiang Y,Wu Y,Hao H,Ji T

GJC2 promoter mutations causing Pelizaeus-Merzbacher-like disease.
Molecular genetics and metabolism111(3)393-398(2014 03)
Gotoh L,Inoue K,Helman G,Mora S,Maski K,Soul JS,Bloom M,Evans SH,Goto YI,Caldovic L,Hobson GM,Vanderver A

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GJC2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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