PSMD9 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PSMD9
Entrez Gene ID	5715
Full Name	proteasome 26S subunit, non-ATPase 9
Synonyms	Rpn4,p27
General protein information	Preferred Names proteasome 26S subunit, non-ATPase 9 Names 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit p27 homolog of rat Bridge 1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 proteasome 26S non-ATPase regulatory subunit 9
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 12 Map Location: 12q24.31
Summary	The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, May 2012].
Disorder MIM:	603146

mRNA and Protein(s)

mRNA	Protein	Name
NM_001261400.2	NP_001248329.1	26S proteasome non-ATPase regulatory subunit 9 isoform 2
NM_001261400.3	NP_001248329.1	26S proteasome non-ATPase regulatory subunit 9 isoform 2
NM_002813.6	NP_002804.2	26S proteasome non-ATPase regulatory subunit 9 isoform 1
NM_002813.7	NP_002804.2	26S proteasome non-ATPase regulatory subunit 9 isoform 1

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Psmd9	NP_080276.2
Magnaporthe oryzae (rice blast fungus)	MGG_09953	XP_003710063.1
Oryza sativa (rice)	Os09g0420600	NP_001063197.1
Pan troglodytes (chimpanzee)	PSMD9	NP_001233329.1
	PSMD9	XP_001096532.1
Canis lupus familiaris (dog)	PSMD9	XP_534665.2
Rattus norvegicus (Norway rat)	Psmd9	NP_569114.1
Gallus gallus (chicken)	PSMD9	NP_001006189.1
Saccharomyces cerevisiae (baker's yeast)	NAS2	NP_012259.3
Kluyveromyces lactis	KLLA0D14135g	XP_453693.1
Arabidopsis thaliana (thale cress)	AT5G57950	NP_568872.1
Homo sapiens (human)	PSMD9	NP_002804.2
Bos taurus (cattle)	PSMD9	NP_001029613.1
Drosophila melanogaster (fruit fly)	CG9588	NP_650301.1
Eremothecium gossypii	AGOS_ADL013C	NP_984084.1
Schizosaccharomyces pombe (fission yeast)	SPAC2H10.02c	NP_594924.1
Neurospora crassa	NCU11053	XP_001728020.1
Xenopus tropicalis (tropical clawed frog)	psmd9	NP_001016559.1
Danio rerio (zebrafish)	psmd9	NP_001002436.2

Gene Ontology
Bibliography

Related articles in PubMed

COPS5 inhibition arrests the proliferation and growth of serous ovarian cancer cells via the elevation of p27 level.
Zhang H, Zhong A, Sun J, Chen M, Xie S, Zheng H, Wang Y, Yu Y, Guo L, Lu R
Biochemical and biophysical research communications493(1)85-93(2017 11)

Testes-specific protease 50 promotes cell proliferation via inhibiting activin signaling.
Song ZB, Wu P, Ni JS, Liu T, Fan C, Bao YL, Wu Y, Sun LG, Yu CL, Huang YX, Li YX
Oncogene36(43)5948-5957(2017 Oct)

Egg antigen p40 of Schistosoma japonicum promotes senescence in activated hepatic stellate cells via SKP2/P27 signaling pathway.
Xu T, Chen J, Zhu D, Chen L, Wang J, Sun X, Hu B, Duan Y
Scientific reports7(1)275(2017 Mar)

Loss of p27 Associated with Risk for Endometrial Carcinoma Arising in the Setting of Obesity.
McCampbell AS, Mittelstadt ML, Dere R, Kim S, Zhou L, Djordjevic B, Soliman PT, Zhang Q, Wei C, Hursting SD, Lu KH, Broaddus RR, Walker CL
Current molecular medicine16(3)252-65(2016)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Furthermore, inhibition of COPS5 resulted in an elevation of Akt expression and sensitized SOC cells to Akt inhibitor MK2206. Suppression of COPS5 and Akt offers a potential strategy for the treatment of SOC.
Title: COPS5 inhibition arrests the proliferation and growth of serous ovarian cancer cells via the elevation of p27 level.

human epidermal growth factor receptor 2 (HER-2) levels, were correlated well with TSP50/p-Samd2/3 and TSP50/p27 expression status. Thus, our studies revealed a novel regulatory mechanism underlying TSP50-induced cell proliferation and provided a new favorable intervention target for the treatment of breast cancer
Title: Testes-specific protease 50 promotes cell proliferation via inhibiting activin signaling.

p53 immunopositivity was more frequent in SCC (65%) than in VC (23%) (P
Title: Expression of Cell Cycle-associated Proteins p53, pRb, p16, p27, and Correlation With Survival: A Comparative Study on Oral Squamous Cell Carcinoma and Verrucous Carcinoma.

Loss of p27 associated with risk for endometrial carcinoma arising in the setting of obesity.
Title: Loss of p27 Associated with Risk for Endometrial Carcinoma Arising in the Setting of Obesity.

Studies have found significant associations of the treatment response with the 26S proteasome non-ATPase subunit 9 (PSMD9), proteasome alpha type 7 subunit (PSMA7) and PSMD13 genes.
Title: Proteasome system dysregulation and treatment resistance mechanisms in major depressive disorder.

The following PSMD9 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PSMD9 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu24127	NM_002813.7 Latest version!	Homo sapiens proteasome 26S subunit, non-ATPase 9 (PSMD9), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu23736	NM_001261400.3 Latest version!	Homo sapiens proteasome 26S subunit, non-ATPase 9 (PSMD9), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
View Old Accession Versions >>
OHu23736	NM_001261400.2	Homo sapiens proteasome 26S subunit, non-ATPase 9 (PSMD9), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu24127	NM_002813.6	Homo sapiens proteasome 26S subunit, non-ATPase 9 (PSMD9), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PSMD9 ( NM_002813.6 ) cDNA ORF clone, Homo sapiens(human) -> NP_002804.2 Homo sapiens proteasome 26S subunit, non-ATPase 9 (PSMD9), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu24127
Clone ID Related Accession (Same CDS sequence)	NM_002813.6 , NM_002813.7
Accession Version	NM_002813.6	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 672bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Homo sapiens(human)
Product	26S proteasome non-ATPase regulatory subunit 9 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CN260241.1, BC002383.2, BU726372.1 and KF459562.1. On Jan 17, 2014 this sequence version replaced NM_002813.5. Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.136375.1, BC002383.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCCGACG AGGAAGCGAG GCAGAGCGGA GGCTCCTCGC AGGCCGGCGT CGTGACTGTC 
AGCGACGTCC AGGAGCTGAT GCGGCGCAAG GAGGAGATAG AAGCGCAGAT CAAGGCCAAC 
TATGACGTGC TGGAAAGCCA AAAAGGCATT GGGATGAACG AGCCGCTGGT GGACTGTGAG 
GGCTACCCCC GGTCAGACGT GGACCTGTAC CAAGTCCGCA CCGCCAGGCA CAACATCATA 
TGCCTGCAGA ATGATCACAA GGCAGTGATG AAGCAGGTGG AGGAGGCCCT GCACCAGCTG 
CACGCTCGCG ACAAGGAGAA GCAGGCCCGG GACATGGCTG AGGCCCACAA AGAGGCCATG 
AGCCGCAAAC TGGGTCAGAG TGAGAGCCAG GGCCCTCCAC GGGCCTTCGC CAAAGTGAAC 
AGCATCAGCC CCGGCTCCCC AGCCAGCATC GCGGGTCTGC AAGTGGATGA TGAGATTGTG 
GAGTTCGGCT CTGTGAACAC CCAGAACTTC CAGTCACTGC ATAACATTGG CAGTGTGGTG 
CAGCACAGTG AGGGGAAGCC CCTGAATGTG ACAGTGATCC GCAGGGGGGA AAAACACCAG 
CTTAGACTTG TTCCAACACG CTGGGCAGGA AAAGGACTGC TGGGCTGCAA CATTATTCCT 
CTGCAAAGAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002804.2
CDS	127..798
Translation	MSDEEARQSGGSSQAGVVTVSDVQELMRRKEEIEAQIKANYDVLESQKGIGMNEPLVDCEGYPRSDVDLYQVRTARHNIICLQNDHKAVMKQVEEALHQLHARDKEKQARDMAEAHKEAMSRKLGQSESQGPPRAFAKVNSISPGSPASIAGLQVDDEIVEFGSVNTQNFQSLHNIGSVVQHSEGKPLNVTVIRRGEKHQLRLVPTRWAGKGLLGCNIIPLQR

Target ORF information:

RefSeq Version	NM_002813.6
Organism	Homo sapiens(human)
Definition	Homo sapiens proteasome 26S subunit, non-ATPase 9 (PSMD9), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002813.6

ORF Insert Sequence:

ATGTCCGACG AGGAAGCGAG GCAGAGCGGA GGCTCCTCGC AGGCCGGCGT CGTGACTGTC 
AGCGACGTCC AGGAGCTGAT GCGGCGCAAG GAGGAGATAG AAGCGCAGAT CAAGGCCAAC 
TATGACGTGC TGGAAAGCCA AAAAGGCATT GGGATGAACG AGCCGCTGGT GGACTGTGAG 
GGCTACCCCC GGTCAGACGT GGACCTGTAC CAAGTCCGCA CCGCCAGGCA CAACATCATA 
TGCCTGCAGA ATGATCACAA GGCAGTGATG AAGCAGGTGG AGGAGGCCCT GCACCAGCTG 
CACGCTCGCG ACAAGGAGAA GCAGGCCCGG GACATGGCTG AGGCCCACAA AGAGGCCATG 
AGCCGCAAAC TGGGTCAGAG TGAGAGCCAG GGCCCTCCAC GGGCCTTCGC CAAAGTGAAC 
AGCATCAGCC CCGGCTCCCC AGCCAGCATC GCGGGTCTGC AAGTGGATGA TGAGATTGTG 
GAGTTCGGCT CTGTGAACAC CCAGAACTTC CAGTCACTGC ATAACATTGG CAGTGTGGTG 
CAGCACAGTG AGGGGAAGCC CCTGAATGTG ACAGTGATCC GCAGGGGGGA AAAACACCAG 
CTTAGACTTG TTCCAACACG CTGGGCAGGA AAAGGACTGC TGGGCTGCAA CATTATTCCT 
CTGCAAAGAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PSMD9 ( NM_002813.7 ) cDNA ORF clone, Homo sapiens(human) -> NP_002804.2 Homo sapiens proteasome 26S subunit, non-ATPase 9 (PSMD9), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu24127
Clone ID Related Accession (Same CDS sequence)	NM_002813.6 , NM_002813.7
Accession Version	NM_002813.7 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 672bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	26S proteasome non-ATPase regulatory subunit 9 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC002383.2, BU726372.1, KF459562.1 and AC069503.25. On May 17, 2019 this sequence version replaced NM_002813.6. Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.36874.1, BC004213.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000541212.6/ ENSP00000440485.1 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGTCCGACG AGGAAGCGAG GCAGAGCGGA GGCTCCTCGC AGGCCGGCGT CGTGACTGTC 
AGCGACGTCC AGGAGCTGAT GCGGCGCAAG GAGGAGATAG AAGCGCAGAT CAAGGCCAAC 
TATGACGTGC TGGAAAGCCA AAAAGGCATT GGGATGAACG AGCCGCTGGT GGACTGTGAG 
GGCTACCCCC GGTCAGACGT GGACCTGTAC CAAGTCCGCA CCGCCAGGCA CAACATCATA 
TGCCTGCAGA ATGATCACAA GGCAGTGATG AAGCAGGTGG AGGAGGCCCT GCACCAGCTG 
CACGCTCGCG ACAAGGAGAA GCAGGCCCGG GACATGGCTG AGGCCCACAA AGAGGCCATG 
AGCCGCAAAC TGGGTCAGAG TGAGAGCCAG GGCCCTCCAC GGGCCTTCGC CAAAGTGAAC 
AGCATCAGCC CCGGCTCCCC AGCCAGCATC GCGGGTCTGC AAGTGGATGA TGAGATTGTG 
GAGTTCGGCT CTGTGAACAC CCAGAACTTC CAGTCACTGC ATAACATTGG CAGTGTGGTG 
CAGCACAGTG AGGGGAAGCC CCTGAATGTG ACAGTGATCC GCAGGGGGGA AAAACACCAG 
CTTAGACTTG TTCCAACACG CTGGGCAGGA AAAGGACTGC TGGGCTGCAA CATTATTCCT 
CTGCAAAGAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002804.2
CDS	68..739
Translation	MSDEEARQSGGSSQAGVVTVSDVQELMRRKEEIEAQIKANYDVLESQKGIGMNEPLVDCEGYPRSDVDLYQVRTARHNIICLQNDHKAVMKQVEEALHQLHARDKEKQARDMAEAHKEAMSRKLGQSESQGPPRAFAKVNSISPGSPASIAGLQVDDEIVEFGSVNTQNFQSLHNIGSVVQHSEGKPLNVTVIRRGEKHQLRLVPTRWAGKGLLGCNIIPLQR

Target ORF information:

RefSeq Version	NM_002813.7
Organism	Homo sapiens(human)
Definition	Homo sapiens proteasome 26S subunit, non-ATPase 9 (PSMD9), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002813.7

ORF Insert Sequence:

ATGTCCGACG AGGAAGCGAG GCAGAGCGGA GGCTCCTCGC AGGCCGGCGT CGTGACTGTC 
AGCGACGTCC AGGAGCTGAT GCGGCGCAAG GAGGAGATAG AAGCGCAGAT CAAGGCCAAC 
TATGACGTGC TGGAAAGCCA AAAAGGCATT GGGATGAACG AGCCGCTGGT GGACTGTGAG 
GGCTACCCCC GGTCAGACGT GGACCTGTAC CAAGTCCGCA CCGCCAGGCA CAACATCATA 
TGCCTGCAGA ATGATCACAA GGCAGTGATG AAGCAGGTGG AGGAGGCCCT GCACCAGCTG 
CACGCTCGCG ACAAGGAGAA GCAGGCCCGG GACATGGCTG AGGCCCACAA AGAGGCCATG 
AGCCGCAAAC TGGGTCAGAG TGAGAGCCAG GGCCCTCCAC GGGCCTTCGC CAAAGTGAAC 
AGCATCAGCC CCGGCTCCCC AGCCAGCATC GCGGGTCTGC AAGTGGATGA TGAGATTGTG 
GAGTTCGGCT CTGTGAACAC CCAGAACTTC CAGTCACTGC ATAACATTGG CAGTGTGGTG 
CAGCACAGTG AGGGGAAGCC CCTGAATGTG ACAGTGATCC GCAGGGGGGA AAAACACCAG 
CTTAGACTTG TTCCAACACG CTGGGCAGGA AAAGGACTGC TGGGCTGCAA CATTATTCCT 
CTGCAAAGAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PSMD9 ( NM_001261400.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001248329.1 Homo sapiens proteasome 26S subunit, non-ATPase 9 (PSMD9), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu23736
Clone ID Related Accession (Same CDS sequence)	NM_001261400.2 , NM_001261400.3
Accession Version	NM_001261400.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 357bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-09-01
Organism	Homo sapiens(human)
Product	26S proteasome non-ATPase regulatory subunit 9 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CN260241.1, BC002383.2, CB111716.1, BU726372.1 and KF459562.1. On Jan 17, 2014 this sequence version replaced NM_001261400.1. Transcript Variant: This variant (2) lacks two alternate in-frame exons compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.64096.1, SRR1660807.268049.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2142586 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCCGACG AGGAAGCGAG GCAGAGCGGA GGCTCCTCGC AGGCCGGCGT CGTGACTGTC 
AGCGACGTCC AGGAGCTGAT GCGGCGCAAG GAGGAGATAG AAGCGCAGAT CAAGGCCAAC 
TATGACGTGC TGGAAAGCGG TCTGCAAGTG GATGATGAGA TTGTGGAGTT CGGCTCTGTG 
AACACCCAGA ACTTCCAGTC ACTGCATAAC ATTGGCAGTG TGGTGCAGCA CAGTGAGGGG 
AAGCCCCTGA ATGTGACAGT GATCCGCAGG GGGGAAAAAC ACCAGCTTAG ACTTGTTCCA 
ACACGCTGGG CAGGAAAAGG ACTGCTGGGC TGCAACATTA TTCCTCTGCA AAGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001248329.1
CDS	127..483
Translation	MSDEEARQSGGSSQAGVVTVSDVQELMRRKEEIEAQIKANYDVLESGLQVDDEIVEFGSVNTQNFQSLHNIGSVVQHSEGKPLNVTVIRRGEKHQLRLVPTRWAGKGLLGCNIIPLQR

Target ORF information:

RefSeq Version	NM_001261400.2
Organism	Homo sapiens(human)
Definition	Homo sapiens proteasome 26S subunit, non-ATPase 9 (PSMD9), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001261400.2

ORF Insert Sequence:

ATGTCCGACG AGGAAGCGAG GCAGAGCGGA GGCTCCTCGC AGGCCGGCGT CGTGACTGTC 
AGCGACGTCC AGGAGCTGAT GCGGCGCAAG GAGGAGATAG AAGCGCAGAT CAAGGCCAAC 
TATGACGTGC TGGAAAGCGG TCTGCAAGTG GATGATGAGA TTGTGGAGTT CGGCTCTGTG 
AACACCCAGA ACTTCCAGTC ACTGCATAAC ATTGGCAGTG TGGTGCAGCA CAGTGAGGGG 
AAGCCCCTGA ATGTGACAGT GATCCGCAGG GGGGAAAAAC ACCAGCTTAG ACTTGTTCCA 
ACACGCTGGG CAGGAAAAGG ACTGCTGGGC TGCAACATTA TTCCTCTGCA AAGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PSMD9 ( NM_001261400.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001248329.1 Homo sapiens proteasome 26S subunit, non-ATPase 9 (PSMD9), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu23736
Clone ID Related Accession (Same CDS sequence)	NM_001261400.2 , NM_001261400.3
Accession Version	NM_001261400.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 357bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-03
Organism	Homo sapiens(human)
Product	26S proteasome non-ATPase regulatory subunit 9 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC002383.2, CB111716.1, BU726372.1, KF459562.1 and AC069503.25. On May 31, 2019 this sequence version replaced NM_001261400.2. Transcript Variant: This variant (2) lacks two alternate in-frame exons compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.64096.1, SRR1660807.268049.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2142586 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCCGACG AGGAAGCGAG GCAGAGCGGA GGCTCCTCGC AGGCCGGCGT CGTGACTGTC 
AGCGACGTCC AGGAGCTGAT GCGGCGCAAG GAGGAGATAG AAGCGCAGAT CAAGGCCAAC 
TATGACGTGC TGGAAAGCGG TCTGCAAGTG GATGATGAGA TTGTGGAGTT CGGCTCTGTG 
AACACCCAGA ACTTCCAGTC ACTGCATAAC ATTGGCAGTG TGGTGCAGCA CAGTGAGGGG 
AAGCCCCTGA ATGTGACAGT GATCCGCAGG GGGGAAAAAC ACCAGCTTAG ACTTGTTCCA 
ACACGCTGGG CAGGAAAAGG ACTGCTGGGC TGCAACATTA TTCCTCTGCA AAGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001248329.1
CDS	68..424
Translation	MSDEEARQSGGSSQAGVVTVSDVQELMRRKEEIEAQIKANYDVLESGLQVDDEIVEFGSVNTQNFQSLHNIGSVVQHSEGKPLNVTVIRRGEKHQLRLVPTRWAGKGLLGCNIIPLQR

Target ORF information:

RefSeq Version	NM_001261400.3
Organism	Homo sapiens(human)
Definition	Homo sapiens proteasome 26S subunit, non-ATPase 9 (PSMD9), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001261400.3

ORF Insert Sequence:

ATGTCCGACG AGGAAGCGAG GCAGAGCGGA GGCTCCTCGC AGGCCGGCGT CGTGACTGTC 
AGCGACGTCC AGGAGCTGAT GCGGCGCAAG GAGGAGATAG AAGCGCAGAT CAAGGCCAAC 
TATGACGTGC TGGAAAGCGG TCTGCAAGTG GATGATGAGA TTGTGGAGTT CGGCTCTGTG 
AACACCCAGA ACTTCCAGTC ACTGCATAAC ATTGGCAGTG TGGTGCAGCA CAGTGAGGGG 
AAGCCCCTGA ATGTGACAGT GATCCGCAGG GGGGAAAAAC ACCAGCTTAG ACTTGTTCCA 
ACACGCTGGG CAGGAAAAGG ACTGCTGGGC TGCAACATTA TTCCTCTGCA AAGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

COPS5 inhibition arrests the proliferation and growth of serous ovarian cancer cells via the elevation of p27 level.
Biochemical and biophysical research communications493(1)85-93(2017 11)
Zhang H,Zhong A,Sun J,Chen M,Xie S,Zheng H,Wang Y,Yu Y,Guo L,Lu R

Testes-specific protease 50 promotes cell proliferation via inhibiting activin signaling.
Oncogene36(43)5948-5957(2017 Oct)
Song ZB,Wu P,Ni JS,Liu T,Fan C,Bao YL,Wu Y,Sun LG,Yu CL,Huang YX,Li YX

Egg antigen p40 of Schistosoma japonicum promotes senescence in activated hepatic stellate cells via SKP2/P27 signaling pathway.
Scientific reports7(1)275(2017 Mar)
Xu T,Chen J,Zhu D,Chen L,Wang J,Sun X,Hu B,Duan Y

Loss of p27 Associated with Risk for Endometrial Carcinoma Arising in the Setting of Obesity.
Current molecular medicine16(3)252-65(2016)
McCampbell AS,Mittelstadt ML,Dere R,Kim S,Zhou L,Djordjevic B,Soliman PT,Zhang Q,Wei C,Hursting SD,Lu KH,Broaddus RR,Walker CL

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PSMD9 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

ORF Insert Sequence:

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Target ORF information:

ORF Insert Sequence:

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