WRNIP1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	WRNIP1
Entrez Gene ID	56897
Full Name	Werner helicase interacting protein 1
Synonyms	WHIP,bA420G6.2
General protein information	Preferred Names Werner helicase interacting protein 1 Names ATPase WRNIP1 putative helicase RUVBL
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 6 Map Location: 6p25.2
Summary	Werner's syndrome is a rare autosomal recessive disorder characterized by accelerated aging that is caused by defects in the Werner syndrome ATP-dependent helicase gene (WRN). The protein encoded by this gene interacts with the exonuclease-containing N-terminal portion of the Werner protein. This protein has a ubiquitin-binding zinc-finger domain in the N-terminus, an ATPase domain, and two leucine zipper motifs in the C-terminus. It has sequence similarity to replication factor C family proteins and is conserved from E. coli to human. This protein likely accumulates at sites of DNA damage by interacting with polyubiquinated proteins and also binds to DNA polymerase delta and increases the initiation frequency of DNA polymerase delta-mediated DNA synthesis. This protein also interacts with nucleoporins at nuclear pore complexes. Two transcript variants encoding different isoforms have been isolated for this gene. [provided by RefSeq, Jul 2012].
Disorder MIM:	608196

mRNA and Protein(s)

mRNA	Protein	Name
XM_005249232.3	XP_005249289.1	ATPase WRNIP1 isoform X2
NM_020135.2	NP_064520.2	ATPase WRNIP1 isoform 1
NM_130395.2	NP_569079.1	ATPase WRNIP1 isoform 2
XM_017011060.1	XP_016866549.1	ATPase WRNIP1 isoform X1
NM_020135.3	NP_064520.2	ATPase WRNIP1 isoform 1
NM_130395.3	NP_569079.1	ATPase WRNIP1 isoform 2

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	WRNIP1	XP_005640033.1
Gallus gallus (chicken)	WRNIP1	XP_418979.2
Homo sapiens (human)	WRNIP1	NP_064520.2
Schizosaccharomyces pombe (fission yeast)	SPAC26H5.02c	NP_594449.2
Neurospora crassa	NCU08706	XP_963567.1
	WRNIP1	XP_001090684.1
Bos taurus (cattle)	WRNIP1	NP_001096576.1
Eremothecium gossypii	AGOS_ABL183W	NP_982764.1
Magnaporthe oryzae (rice blast fungus)	MGG_17505	XP_003718908.1
Xenopus tropicalis (tropical clawed frog)	wrnip1	NP_001121492.1
Mus musculus (house mouse)	Wrnip1	NP_084491.3
Danio rerio (zebrafish)	wrnip1	NP_998085.1
Saccharomyces cerevisiae (baker's yeast)	MGS1	NP_014181.1
Kluyveromyces lactis	KLLA0D19360g	XP_453921.1
Pan troglodytes (chimpanzee)	WRNIP1	XP_003950752.1
Rattus norvegicus (Norway rat)	Wrnip1	NP_758835.1
Arabidopsis thaliana (thale cress)	AT1G24290	NP_173839.1

Gene Ontology
Bibliography

Related articles in PubMed

Assembly of the WHIP-TRIM14-PPP6C Mitochondrial Complex Promotes RIG-I-Mediated Antiviral Signaling.
Tan P, He L, Cui J, Qian C, Cao X, Lin M, Zhu Q, Li Y, Xing C, Yu X, Wang HY, Wang RF
Molecular cell68(2)293-307.e5(2017 Oct)

WRNIP1 protects stalled forks from degradation and promotes fork restart after replication stress.
Leuzzi G, Marabitti V, Pichierri P, Franchitto A
The EMBO journal35(13)1437-51(2016 07)

RAD18, WRNIP1 and ATMIN promote ATM signalling in response to replication stress.
Kanu N, Zhang T, Burrell RA, Chakraborty A, Cronshaw J, DaCosta C, Gr?nroos E, Pemberton HN, Anderton E, Gonzalez L, Sabbioneda S, Ulrich HD, Swanton C, Behrens A
Oncogene35(30)4009-19(2016 Jul)

A novel mode of ubiquitin recognition by the ubiquitin-binding zinc finger domain of WRNIP1.
Suzuki N, Rohaim A, Kato R, Dikic I, Wakatsuki S, Kawasaki M
The FEBS journal283(11)2004-17(2016 06)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

findings define the WHIP-TRIM14-PPP6C mitochondrial signalosome required for RIG-I-mediated innate antiviral immunity.
Title: Assembly of the WHIP-TRIM14-PPP6C Mitochondrial Complex Promotes RIG-I-Mediated Antiviral Signaling.

The authors show that WRNIP1 is directly involved in preventing uncontrolled MRE11-mediated degradation of stalled replication forks by promoting RAD51 stabilization on ssDNA.
Title: WRNIP1 protects stalled forks from degradation and promotes fork restart after replication stress.

WRNIP1 connects PCNA monoubiquitination with ATMIN/ATM to activate ATM signalling in response to replication stress and contribute to the maintenance of genomic stability.
Title: RAD18, WRNIP1 and ATMIN promote ATM signalling in response to replication stress.

We propose that UBZ domains can be divided into at least two different types in terms of the ubiquitin-binding surfaces: the pol type and the WRNIP1 type
Title: A novel mode of ubiquitin recognition by the ubiquitin-binding zinc finger domain of WRNIP1.

results suggest that WRNIP1 functions upstream of Poleta in the response to UV irradiation
Title: WRNIP1 functions upstream of DNA polymerase ? in the UV-induced DNA damage response.

The following WRNIP1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the WRNIP1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu13035	NM_020135.3 Latest version!	Homo sapiens WRN helicase interacting protein 1 (WRNIP1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00
OHu14044	NM_130395.3 Latest version!	Homo sapiens WRN helicase interacting protein 1 (WRNIP1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$265.30 $379.00
OHu40386	XM_005249232.3 Latest version!	Homo sapiens WRN helicase interacting protein 1 (WRNIP1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
OHu96692	XM_017011060.1 Latest version!	Homo sapiens WRN helicase interacting protein 1 (WRNIP1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
View Old Accession Versions >>
OHu13035	NM_020135.2	Homo sapiens Werner helicase interacting protein 1 (WRNIP1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00
OHu14044	NM_130395.2	Homo sapiens Werner helicase interacting protein 1 (WRNIP1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

WRNIP1 ( NM_020135.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_064520.2 Homo sapiens Werner helicase interacting protein 1 (WRNIP1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu13035
Clone ID Related Accession (Same CDS sequence)	NM_020135.2 , NM_020135.3
Accession Version	NM_020135.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1998bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-15
Organism	Homo sapiens(human)
Product	ATPase WRNIP1 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AB056152.1. On Jan 30, 2002 this sequence version replaced NM_020135.1. Transcript Variant: This variant (1) encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB056152.1, SRR1163655.621428.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGGTGA GCGGGCCGGA AGACGACCCC TTCCTTTCGC AGCTGCACCA GGTGCAGTGC 
CCCGTGTGCC AGCAGATGAT GCCCGCCGCG CACATCAACT CGCACCTGGA CCGCTGTCTG 
CTGCTCCACC CGGCGGGGCA CGCGGAGCCC GCGGCCGGGT CGCACCGCGC CGGGGAGCGG 
GCCAAGGGGC CCTCGCCGCC CGGCGCCAAG AGGCGGCGGC TGTCGGAGAG CTCGGCGCTG 
AAGCAGCCAG CCACCCCGAC GGCAGCCGAG AGCAGCGAGG GCGAGGGTGA GGAGGGCGAC 
GACGGCGGCG AGACCGAGAG CCGCGAGAGC TACGACGCGC CGCCCACACC CAGCGGCGCC 
CGCCTTATCC CCGACTTCCC GGTGGCCCGC TCCAGCAGCC CCGGGAGGAA GGGGTCGGGG 
AAGAGGCCGG CGGCCGCCGC CGCGGCGGGG AGCGCGTCTC CGCGCAGCTG GGACGAGGCG 
GAGGCGCAGG AGGAGGAGGA GGCCGTGGGC GACGGCGATG GCGACGGGGA CGCGGACGCG 
GACGGCGAGG ACGACCCGGG GCACTGGGAC GCGGACGCTG CCGAAGCCGC CACCGCCTTC 
GGGGCCAGTG GCGGGGGCCG CCCGCACCCC CGGGCGCTGG CTGCCGAGGA GATCCGACAG 
ATGCTACAGG GCAAGCCGCT GGCCGACACG ATGCGTCCTG ACACGCTGCA GGATTACTTC 
GGGCAGAGCA AGGCCGTGGG CCAGGATACC CTGCTGCGCT CGCTCCTGGA GACCAACGAA 
ATCCCCTCGC TTATCCTGTG GGGGCCGCCG GGCTGCGGCA AGACCACTCT GGCTCACATC 
ATAGCCAGCA ACAGCAAGAA ACATAGCATA AGGTTTGTGA CATTATCTGC AACAAATGCC 
AAGACAAATG ATGTGCGAGA TGTCATAAAA CAAGCTCAAA ATGAAAAGAG CTTTTTCAAA 
AGGAAAACCA TCCTTTTTAT TGATGAGATT CATCGGTTCA ATAAATCTCA GCAGGACACT 
TTCCTTCCTC ACGTGGAATG TGGGACGATC ACTCTGATTG GGGCAACCAC TGAAAACCCT 
TCCTTCCAGG TCAACGCTGC TCTTCTGAGC CGCTGTCGAG TGATTGTTCT TGAGAAGCTT 
CCAGTAGAGG CAATGGTGAC TATTTTAATG CGAGCGATCA ACTCCCTGGG AATCCACGTC 
CTAGACTCTA GCCGTCCCAC TGACCCTCTG AGCCACAGCA GCAACAGCAG CTCAGAGCCC 
GCCATGTTCA TAGAGGATAA AGCAGTAGAC ACCCTGGCTT ACCTCAGTGA CGGTGACGCC 
CGAGCTGGGT TGAACGGACT GCAGCTGGCG GTGCTGGCTA GGTTAAGCTC TAGGAAGATG 
TTCTGTAAGA AGAGTGGGCA ATCCTATTCT CCCAGTAGAG TTCTGATCAC AGAGAATGAC 
GTGAAGGAGG GCCTACAGCG ATCCCACATT TTATATGACC GGGCAGGTGA GGAGCATTAC 
AACTGCATCT CCGCCCTGCA CAAGTCCATG CGGGGCTCAG ACCAGAACGC CTCCCTCTAC 
TGGCTGGCTC GCATGCTCGA GGGAGGAGAG GACCCACTCT ACGTGGCACG GAGGCTTGTC 
AGGTTTGCCA GCGAGGACAT AGGTCTGGCA GACCCGTCTG CGTTAACACA AGCGGTTGCT 
GCCTACCAAG GCTGTCATTT TATAGGCATG CCTGAATGTG AGGTGCTTCT GGCCCAGTGT 
GTGGTCTACT TTGCCAGAGC CCCAAAGTCC ATTGAGGTGT ACAGCGCCTA CAACAACGTC 
AAAGCCTGCC TGAGGAACCA CCAGGGGCCA CTGCCCCCCG TGCCCCTGCA CCTGAGGAAC 
GCGCCCACTA GGCTGATGAA GGATTTGGGC TATGGCAAAG GCTACAAGTA CAACCCCATG 
TACAGCGAGC CTGTGGATCA GGAGTACCTG CCTGAAGAGT TGAGGGGGGT AGATTTCTTC 
AAGCAGAGGA GGTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_064520.2
CDS	192..2189
Translation	MEVSGPEDDPFLSQLHQVQCPVCQQMMPAAHINSHLDRCLLLHPAGHAEPAAGSHRAGERAKGPSPPGAKRRRLSESSALKQPATPTAAESSEGEGEEGDDGGETESRESYDAPPTPSGARLIPDFPVARSSSPGRKGSGKRPAAAAAAGSASPRSWDEAEAQEEEEAVGDGDGDGDADADGEDDPGHWDADAAEAATAFGASGGGRPHPRALAAEEIRQMLQGKPLADTMRPDTLQDYFGQSKAVGQDTLLRSLLETNEIPSLILWGPPGCGKTTLAHIIASNSKKHSIRFVTLSATNAKTNDVRDVIKQAQNEKSFFKRKTILFIDEIHRFNKSQQDTFLPHVECGTITLIGATTENPSFQVNAALLSRCRVIVLEKLPVEAMVTILMRAINSLGIHVLDSSRPTDPLSHSSNSSSEPAMFIEDKAVDTLAYLSDGDARAGLNGLQLAVLARLSSRKMFCKKSGQSYSPSRVLITENDVKEGLQRSHILYDRAGEEHYNCISALHKSMRGSDQNASLYWLARMLEGGEDPLYVARRLVRFASEDIGLADPSALTQAVAAYQGCHFIGMPECEVLLAQCVVYFARAPKSIEVYSAYNNVKACLRNHQGPLPPVPLHLRNAPTRLMKDLGYGKGYKYNPMYSEPVDQEYLPEELRGVDFFKQRRC

Target ORF information:

RefSeq Version	NM_020135.2
Organism	Homo sapiens(human)
Definition	Homo sapiens Werner helicase interacting protein 1 (WRNIP1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_020135.2

ORF Insert Sequence:

ATGGAGGTGA GCGGGCCGGA AGACGACCCC TTCCTTTCGC AGCTGCACCA GGTGCAGTGC 
CCCGTGTGCC AGCAGATGAT GCCCGCCGCG CACATCAACT CGCACCTGGA CCGCTGTCTG 
CTGCTCCACC CGGCGGGGCA CGCGGAGCCC GCGGCCGGGT CGCACCGCGC CGGGGAGCGG 
GCCAAGGGGC CCTCGCCGCC CGGCGCCAAG AGGCGGCGGC TGTCGGAGAG CTCGGCGCTG 
AAGCAGCCAG CCACCCCGAC GGCAGCCGAG AGCAGCGAGG GCGAGGGTGA GGAGGGCGAC 
GACGGCGGCG AGACCGAGAG CCGCGAGAGC TACGACGCGC CGCCCACACC CAGCGGCGCC 
CGCCTTATCC CCGACTTCCC GGTGGCCCGC TCCAGCAGCC CCGGGAGGAA GGGGTCGGGG 
AAGAGGCCGG CGGCCGCCGC CGCGGCGGGG AGCGCGTCTC CGCGCAGCTG GGACGAGGCG 
GAGGCGCAGG AGGAGGAGGA GGCCGTGGGC GACGGCGATG GCGACGGGGA CGCGGACGCG 
GACGGCGAGG ACGACCCGGG GCACTGGGAC GCGGACGCTG CCGAAGCCGC CACCGCCTTC 
GGGGCCAGTG GCGGGGGCCG CCCGCACCCC CGGGCGCTGG CTGCCGAGGA GATCCGACAG 
ATGCTACAGG GCAAGCCGCT GGCCGACACG ATGCGTCCTG ACACGCTGCA GGATTACTTC 
GGGCAGAGCA AGGCCGTGGG CCAGGATACC CTGCTGCGCT CGCTCCTGGA GACCAACGAA 
ATCCCCTCGC TTATCCTGTG GGGGCCGCCG GGCTGCGGCA AGACCACTCT GGCTCACATC 
ATAGCCAGCA ACAGCAAGAA ACATAGCATA AGGTTTGTGA CATTATCTGC AACAAATGCC 
AAGACAAATG ATGTGCGAGA TGTCATAAAA CAAGCTCAAA ATGAAAAGAG CTTTTTCAAA 
AGGAAAACCA TCCTTTTTAT TGATGAGATT CATCGGTTCA ATAAATCTCA GCAGGACACT 
TTCCTTCCTC ACGTGGAATG TGGGACGATC ACTCTGATTG GGGCAACCAC TGAAAACCCT 
TCCTTCCAGG TCAACGCTGC TCTTCTGAGC CGCTGTCGAG TGATTGTTCT TGAGAAGCTT 
CCAGTAGAGG CAATGGTGAC TATTTTAATG CGAGCGATCA ACTCCCTGGG AATCCACGTC 
CTAGACTCTA GCCGTCCCAC TGACCCTCTG AGCCACAGCA GCAACAGCAG CTCAGAGCCC 
GCCATGTTCA TAGAGGATAA AGCAGTAGAC ACCCTGGCTT ACCTCAGTGA CGGTGACGCC 
CGAGCTGGGT TGAACGGACT GCAGCTGGCG GTGCTGGCTA GGTTAAGCTC TAGGAAGATG 
TTCTGTAAGA AGAGTGGGCA ATCCTATTCT CCCAGTAGAG TTCTGATCAC AGAGAATGAC 
GTGAAGGAGG GCCTACAGCG ATCCCACATT TTATATGACC GGGCAGGTGA GGAGCATTAC 
AACTGCATCT CCGCCCTGCA CAAGTCCATG CGGGGCTCAG ACCAGAACGC CTCCCTCTAC 
TGGCTGGCTC GCATGCTCGA GGGAGGAGAG GACCCACTCT ACGTGGCACG GAGGCTTGTC 
AGGTTTGCCA GCGAGGACAT AGGTCTGGCA GACCCGTCTG CGTTAACACA AGCGGTTGCT 
GCCTACCAAG GCTGTCATTT TATAGGCATG CCTGAATGTG AGGTGCTTCT GGCCCAGTGT 
GTGGTCTACT TTGCCAGAGC CCCAAAGTCC ATTGAGGTGT ACAGCGCCTA CAACAACGTC 
AAAGCCTGCC TGAGGAACCA CCAGGGGCCA CTGCCCCCCG TGCCCCTGCA CCTGAGGAAC 
GCGCCCACTA GGCTGATGAA GGATTTGGGC TATGGCAAAG GCTACAAGTA CAACCCCATG 
TACAGCGAGC CTGTGGATCA GGAGTACCTG CCTGAAGAGT TGAGGGGGGT AGATTTCTTC 
AAGCAGAGGA GGTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

WRNIP1 ( NM_020135.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_064520.2 Homo sapiens WRN helicase interacting protein 1 (WRNIP1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu13035
Clone ID Related Accession (Same CDS sequence)	NM_020135.2 , NM_020135.3
Accession Version	NM_020135.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1998bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-24
Organism	Homo sapiens(human)
Product	ATPase WRNIP1 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL139092.12. On May 17, 2019 this sequence version replaced NM_020135.2. Transcript Variant: This variant (1) encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF218313.2, AB056152.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000380773.9/ ENSP00000370150.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGAGGTGA GCGGGCCGGA AGACGACCCC TTCCTTTCGC AGCTGCACCA GGTGCAGTGC 
CCCGTGTGCC AGCAGATGAT GCCCGCCGCG CACATCAACT CGCACCTGGA CCGCTGTCTG 
CTGCTCCACC CGGCGGGGCA CGCGGAGCCC GCGGCCGGGT CGCACCGCGC CGGGGAGCGG 
GCCAAGGGGC CCTCGCCGCC CGGCGCCAAG AGGCGGCGGC TGTCGGAGAG CTCGGCGCTG 
AAGCAGCCAG CCACCCCGAC GGCAGCCGAG AGCAGCGAGG GCGAGGGTGA GGAGGGCGAC 
GACGGCGGCG AGACCGAGAG CCGCGAGAGC TACGACGCGC CGCCCACACC CAGCGGCGCC 
CGCCTTATCC CCGACTTCCC GGTGGCCCGC TCCAGCAGCC CCGGGAGGAA GGGGTCGGGG 
AAGAGGCCGG CGGCCGCCGC CGCGGCGGGG AGCGCGTCTC CGCGCAGCTG GGACGAGGCG 
GAGGCGCAGG AGGAGGAGGA GGCCGTGGGC GACGGCGATG GCGACGGGGA CGCGGACGCG 
GACGGCGAGG ACGACCCGGG GCACTGGGAC GCGGACGCTG CCGAAGCCGC CACCGCCTTC 
GGGGCCAGTG GCGGGGGCCG CCCGCACCCC CGGGCGCTGG CTGCCGAGGA GATCCGACAG 
ATGCTACAGG GCAAGCCGCT GGCCGACACG ATGCGTCCTG ACACGCTGCA GGATTACTTC 
GGGCAGAGCA AGGCCGTGGG CCAGGATACC CTGCTGCGCT CGCTCCTGGA GACCAACGAA 
ATCCCCTCGC TTATCCTGTG GGGGCCGCCG GGCTGCGGCA AGACCACTCT GGCTCACATC 
ATAGCCAGCA ACAGCAAGAA ACATAGCATA AGGTTTGTGA CATTATCTGC AACAAATGCC 
AAGACAAATG ATGTGCGAGA TGTCATAAAA CAAGCTCAAA ATGAAAAGAG CTTTTTCAAA 
AGGAAAACCA TCCTTTTTAT TGATGAGATT CATCGGTTCA ATAAATCTCA GCAGGACACT 
TTCCTTCCTC ACGTGGAATG TGGGACGATC ACTCTGATTG GGGCAACCAC TGAAAACCCT 
TCCTTCCAGG TCAACGCTGC TCTTCTGAGC CGCTGTCGAG TGATTGTTCT TGAGAAGCTT 
CCAGTAGAGG CAATGGTGAC TATTTTAATG CGAGCGATCA ACTCCCTGGG AATCCACGTC 
CTAGACTCTA GCCGTCCCAC TGACCCTCTG AGCCACAGCA GCAACAGCAG CTCAGAGCCC 
GCCATGTTCA TAGAGGATAA AGCAGTAGAC ACCCTGGCTT ACCTCAGTGA CGGTGACGCC 
CGAGCTGGGT TGAACGGACT GCAGCTGGCG GTGCTGGCTA GGTTAAGCTC TAGGAAGATG 
TTCTGTAAGA AGAGTGGGCA ATCCTATTCT CCCAGTAGAG TTCTGATCAC AGAGAATGAC 
GTGAAGGAGG GCCTACAGCG ATCCCACATT TTATATGACC GGGCAGGTGA GGAGCATTAC 
AACTGCATCT CCGCCCTGCA CAAGTCCATG CGGGGCTCAG ACCAGAACGC CTCCCTCTAC 
TGGCTGGCTC GCATGCTCGA GGGAGGAGAG GACCCACTCT ACGTGGCACG GAGGCTTGTC 
AGGTTTGCCA GCGAGGACAT AGGTCTGGCA GACCCGTCTG CGTTAACACA AGCGGTTGCT 
GCCTACCAAG GCTGTCATTT TATAGGCATG CCTGAATGTG AGGTGCTTCT GGCCCAGTGT 
GTGGTCTACT TTGCCAGAGC CCCAAAGTCC ATTGAGGTGT ACAGCGCCTA CAACAACGTC 
AAAGCCTGCC TGAGGAACCA CCAGGGGCCA CTGCCCCCCG TGCCCCTGCA CCTGAGGAAC 
GCGCCCACTA GGCTGATGAA GGATTTGGGC TATGGCAAAG GCTACAAGTA CAACCCCATG 
TACAGCGAGC CTGTGGATCA GGAGTACCTG CCTGAAGAGT TGAGGGGGGT AGATTTCTTC 
AAGCAGAGGA GGTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_064520.2
CDS	231..2228
Translation	MEVSGPEDDPFLSQLHQVQCPVCQQMMPAAHINSHLDRCLLLHPAGHAEPAAGSHRAGERAKGPSPPGAKRRRLSESSALKQPATPTAAESSEGEGEEGDDGGETESRESYDAPPTPSGARLIPDFPVARSSSPGRKGSGKRPAAAAAAGSASPRSWDEAEAQEEEEAVGDGDGDGDADADGEDDPGHWDADAAEAATAFGASGGGRPHPRALAAEEIRQMLQGKPLADTMRPDTLQDYFGQSKAVGQDTLLRSLLETNEIPSLILWGPPGCGKTTLAHIIASNSKKHSIRFVTLSATNAKTNDVRDVIKQAQNEKSFFKRKTILFIDEIHRFNKSQQDTFLPHVECGTITLIGATTENPSFQVNAALLSRCRVIVLEKLPVEAMVTILMRAINSLGIHVLDSSRPTDPLSHSSNSSSEPAMFIEDKAVDTLAYLSDGDARAGLNGLQLAVLARLSSRKMFCKKSGQSYSPSRVLITENDVKEGLQRSHILYDRAGEEHYNCISALHKSMRGSDQNASLYWLARMLEGGEDPLYVARRLVRFASEDIGLADPSALTQAVAAYQGCHFIGMPECEVLLAQCVVYFARAPKSIEVYSAYNNVKACLRNHQGPLPPVPLHLRNAPTRLMKDLGYGKGYKYNPMYSEPVDQEYLPEELRGVDFFKQRRC

Target ORF information:

RefSeq Version	NM_020135.3
Organism	Homo sapiens(human)
Definition	Homo sapiens WRN helicase interacting protein 1 (WRNIP1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_020135.3

ORF Insert Sequence:

ATGGAGGTGA GCGGGCCGGA AGACGACCCC TTCCTTTCGC AGCTGCACCA GGTGCAGTGC 
CCCGTGTGCC AGCAGATGAT GCCCGCCGCG CACATCAACT CGCACCTGGA CCGCTGTCTG 
CTGCTCCACC CGGCGGGGCA CGCGGAGCCC GCGGCCGGGT CGCACCGCGC CGGGGAGCGG 
GCCAAGGGGC CCTCGCCGCC CGGCGCCAAG AGGCGGCGGC TGTCGGAGAG CTCGGCGCTG 
AAGCAGCCAG CCACCCCGAC GGCAGCCGAG AGCAGCGAGG GCGAGGGTGA GGAGGGCGAC 
GACGGCGGCG AGACCGAGAG CCGCGAGAGC TACGACGCGC CGCCCACACC CAGCGGCGCC 
CGCCTTATCC CCGACTTCCC GGTGGCCCGC TCCAGCAGCC CCGGGAGGAA GGGGTCGGGG 
AAGAGGCCGG CGGCCGCCGC CGCGGCGGGG AGCGCGTCTC CGCGCAGCTG GGACGAGGCG 
GAGGCGCAGG AGGAGGAGGA GGCCGTGGGC GACGGCGATG GCGACGGGGA CGCGGACGCG 
GACGGCGAGG ACGACCCGGG GCACTGGGAC GCGGACGCTG CCGAAGCCGC CACCGCCTTC 
GGGGCCAGTG GCGGGGGCCG CCCGCACCCC CGGGCGCTGG CTGCCGAGGA GATCCGACAG 
ATGCTACAGG GCAAGCCGCT GGCCGACACG ATGCGTCCTG ACACGCTGCA GGATTACTTC 
GGGCAGAGCA AGGCCGTGGG CCAGGATACC CTGCTGCGCT CGCTCCTGGA GACCAACGAA 
ATCCCCTCGC TTATCCTGTG GGGGCCGCCG GGCTGCGGCA AGACCACTCT GGCTCACATC 
ATAGCCAGCA ACAGCAAGAA ACATAGCATA AGGTTTGTGA CATTATCTGC AACAAATGCC 
AAGACAAATG ATGTGCGAGA TGTCATAAAA CAAGCTCAAA ATGAAAAGAG CTTTTTCAAA 
AGGAAAACCA TCCTTTTTAT TGATGAGATT CATCGGTTCA ATAAATCTCA GCAGGACACT 
TTCCTTCCTC ACGTGGAATG TGGGACGATC ACTCTGATTG GGGCAACCAC TGAAAACCCT 
TCCTTCCAGG TCAACGCTGC TCTTCTGAGC CGCTGTCGAG TGATTGTTCT TGAGAAGCTT 
CCAGTAGAGG CAATGGTGAC TATTTTAATG CGAGCGATCA ACTCCCTGGG AATCCACGTC 
CTAGACTCTA GCCGTCCCAC TGACCCTCTG AGCCACAGCA GCAACAGCAG CTCAGAGCCC 
GCCATGTTCA TAGAGGATAA AGCAGTAGAC ACCCTGGCTT ACCTCAGTGA CGGTGACGCC 
CGAGCTGGGT TGAACGGACT GCAGCTGGCG GTGCTGGCTA GGTTAAGCTC TAGGAAGATG 
TTCTGTAAGA AGAGTGGGCA ATCCTATTCT CCCAGTAGAG TTCTGATCAC AGAGAATGAC 
GTGAAGGAGG GCCTACAGCG ATCCCACATT TTATATGACC GGGCAGGTGA GGAGCATTAC 
AACTGCATCT CCGCCCTGCA CAAGTCCATG CGGGGCTCAG ACCAGAACGC CTCCCTCTAC 
TGGCTGGCTC GCATGCTCGA GGGAGGAGAG GACCCACTCT ACGTGGCACG GAGGCTTGTC 
AGGTTTGCCA GCGAGGACAT AGGTCTGGCA GACCCGTCTG CGTTAACACA AGCGGTTGCT 
GCCTACCAAG GCTGTCATTT TATAGGCATG CCTGAATGTG AGGTGCTTCT GGCCCAGTGT 
GTGGTCTACT TTGCCAGAGC CCCAAAGTCC ATTGAGGTGT ACAGCGCCTA CAACAACGTC 
AAAGCCTGCC TGAGGAACCA CCAGGGGCCA CTGCCCCCCG TGCCCCTGCA CCTGAGGAAC 
GCGCCCACTA GGCTGATGAA GGATTTGGGC TATGGCAAAG GCTACAAGTA CAACCCCATG 
TACAGCGAGC CTGTGGATCA GGAGTACCTG CCTGAAGAGT TGAGGGGGGT AGATTTCTTC 
AAGCAGAGGA GGTGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

WRNIP1 ( NM_130395.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_569079.1 Homo sapiens Werner helicase interacting protein 1 (WRNIP1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu14044
Clone ID Related Accession (Same CDS sequence)	NM_130395.2 , NM_130395.3
Accession Version	NM_130395.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1923bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-24
Organism	Homo sapiens(human)
Product	ATPase WRNIP1 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK315047.1 and BC018923.2. On Jul 27, 2012 this sequence version replaced NM_130395.1. Transcript Variant: This variant (2) utilizes a different acceptor splice site for an internal coding exon, compared to transcript variant 1. This variant maintains the same reading frame but encodes an isoform (2) which is 25 aa shorter than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC018923.2, AK315471.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGGTGA GCGGGCCGGA AGACGACCCC TTCCTTTCGC AGCTGCACCA GGTGCAGTGC 
CCCGTGTGCC AGCAGATGAT GCCCGCCGCG CACATCAACT CGCACCTGGA CCGCTGTCTG 
CTGCTCCACC CGGCGGGGCA CGCGGAGCCC GCGGCCGGGT CGCACCGCGC CGGGGAGCGG 
GCCAAGGGGC CCTCGCCGCC CGGCGCCAAG AGGCGGCGGC TGTCGGAGAG CTCGGCGCTG 
AAGCAGCCAG CCACCCCGAC GGCAGCCGAG AGCAGCGAGG GCGAGGGTGA GGAGGGCGAC 
GACGGCGGCG AGACCGAGAG CCGCGAGAGC TACGACGCGC CGCCCACACC CAGCGGCGCC 
CGCCTTATCC CCGACTTCCC GGTGGCCCGC TCCAGCAGCC CCGGGAGGAA GGGGTCGGGG 
AAGAGGCCGG CGGCCGCCGC CGCGGCGGGG AGCGCGTCTC CGCGCAGCTG GGACGAGGCG 
GAGGCGCAGG AGGAGGAGGA GGCCGTGGGC GACGGCGATG GCGACGGGGA CGCGGACGCG 
GACGGCGAGG ACGACCCGGG GCACTGGGAC GCGGACGCTG CCGAAGCCGC CACCGCCTTC 
GGGGCCAGTG GCGGGGGCCG CCCGCACCCC CGGGCGCTGG CTGCCGAGGA GATCCGACAG 
ATGCTACAGG GCAAGCCGCT GGCCGACACG ATGCGTCCTG ACACGCTGCA GGATTACTTC 
GGGCAGAGCA AGGCCGTGGG CCAGGATACC CTGCTGCGCT CGCTCCTGGA GACCAACGAA 
ATCCCCTCGC TTATCCTGTG GGGGCCGCCG GGCTGCGGCA AGACCACTCT GGCTCACATC 
ATAGCCAGCA ACAGCAAGAA ACATAGCATA AGGTTTGTGA CATTATCTGC AACAAATGCC 
AAGACAAATG ATGTGCGAGA TGTCATAAAA CAAGCTCAAA ATGAAAAGAG CTTTTTCAAA 
AGGAAAACCA TCCTTTTTAT TGATGAGATT CATCGGTTCA ATAAATCTCA GCAGGTCAAC 
GCTGCTCTTC TGAGCCGCTG TCGAGTGATT GTTCTTGAGA AGCTTCCAGT AGAGGCAATG 
GTGACTATTT TAATGCGAGC GATCAACTCC CTGGGAATCC ACGTCCTAGA CTCTAGCCGT 
CCCACTGACC CTCTGAGCCA CAGCAGCAAC AGCAGCTCAG AGCCCGCCAT GTTCATAGAG 
GATAAAGCAG TAGACACCCT GGCTTACCTC AGTGACGGTG ACGCCCGAGC TGGGTTGAAC 
GGACTGCAGC TGGCGGTGCT GGCTAGGTTA AGCTCTAGGA AGATGTTCTG TAAGAAGAGT 
GGGCAATCCT ATTCTCCCAG TAGAGTTCTG ATCACAGAGA ATGACGTGAA GGAGGGCCTA 
CAGCGATCCC ACATTTTATA TGACCGGGCA GGTGAGGAGC ATTACAACTG CATCTCCGCC 
CTGCACAAGT CCATGCGGGG CTCAGACCAG AACGCCTCCC TCTACTGGCT GGCTCGCATG 
CTCGAGGGAG GAGAGGACCC ACTCTACGTG GCACGGAGGC TTGTCAGGTT TGCCAGCGAG 
GACATAGGTC TGGCAGACCC GTCTGCGTTA ACACAAGCGG TTGCTGCCTA CCAAGGCTGT 
CATTTTATAG GCATGCCTGA ATGTGAGGTG CTTCTGGCCC AGTGTGTGGT CTACTTTGCC 
AGAGCCCCAA AGTCCATTGA GGTGTACAGC GCCTACAACA ACGTCAAAGC CTGCCTGAGG 
AACCACCAGG GGCCACTGCC CCCCGTGCCC CTGCACCTGA GGAACGCGCC CACTAGGCTG 
ATGAAGGATT TGGGCTATGG CAAAGGCTAC AAGTACAACC CCATGTACAG CGAGCCTGTG 
GATCAGGAGT ACCTGCCTGA AGAGTTGAGG GGGGTAGATT TCTTCAAGCA GAGGAGGTGC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_569079.1
CDS	192..2114
Translation	MEVSGPEDDPFLSQLHQVQCPVCQQMMPAAHINSHLDRCLLLHPAGHAEPAAGSHRAGERAKGPSPPGAKRRRLSESSALKQPATPTAAESSEGEGEEGDDGGETESRESYDAPPTPSGARLIPDFPVARSSSPGRKGSGKRPAAAAAAGSASPRSWDEAEAQEEEEAVGDGDGDGDADADGEDDPGHWDADAAEAATAFGASGGGRPHPRALAAEEIRQMLQGKPLADTMRPDTLQDYFGQSKAVGQDTLLRSLLETNEIPSLILWGPPGCGKTTLAHIIASNSKKHSIRFVTLSATNAKTNDVRDVIKQAQNEKSFFKRKTILFIDEIHRFNKSQQVNAALLSRCRVIVLEKLPVEAMVTILMRAINSLGIHVLDSSRPTDPLSHSSNSSSEPAMFIEDKAVDTLAYLSDGDARAGLNGLQLAVLARLSSRKMFCKKSGQSYSPSRVLITENDVKEGLQRSHILYDRAGEEHYNCISALHKSMRGSDQNASLYWLARMLEGGEDPLYVARRLVRFASEDIGLADPSALTQAVAAYQGCHFIGMPECEVLLAQCVVYFARAPKSIEVYSAYNNVKACLRNHQGPLPPVPLHLRNAPTRLMKDLGYGKGYKYNPMYSEPVDQEYLPEELRGVDFFKQRRC

Target ORF information:

RefSeq Version	NM_130395.2
Organism	Homo sapiens(human)
Definition	Homo sapiens Werner helicase interacting protein 1 (WRNIP1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_130395.2

ORF Insert Sequence:

ATGGAGGTGA GCGGGCCGGA AGACGACCCC TTCCTTTCGC AGCTGCACCA GGTGCAGTGC 
CCCGTGTGCC AGCAGATGAT GCCCGCCGCG CACATCAACT CGCACCTGGA CCGCTGTCTG 
CTGCTCCACC CGGCGGGGCA CGCGGAGCCC GCGGCCGGGT CGCACCGCGC CGGGGAGCGG 
GCCAAGGGGC CCTCGCCGCC CGGCGCCAAG AGGCGGCGGC TGTCGGAGAG CTCGGCGCTG 
AAGCAGCCAG CCACCCCGAC GGCAGCCGAG AGCAGCGAGG GCGAGGGTGA GGAGGGCGAC 
GACGGCGGCG AGACCGAGAG CCGCGAGAGC TACGACGCGC CGCCCACACC CAGCGGCGCC 
CGCCTTATCC CCGACTTCCC GGTGGCCCGC TCCAGCAGCC CCGGGAGGAA GGGGTCGGGG 
AAGAGGCCGG CGGCCGCCGC CGCGGCGGGG AGCGCGTCTC CGCGCAGCTG GGACGAGGCG 
GAGGCGCAGG AGGAGGAGGA GGCCGTGGGC GACGGCGATG GCGACGGGGA CGCGGACGCG 
GACGGCGAGG ACGACCCGGG GCACTGGGAC GCGGACGCTG CCGAAGCCGC CACCGCCTTC 
GGGGCCAGTG GCGGGGGCCG CCCGCACCCC CGGGCGCTGG CTGCCGAGGA GATCCGACAG 
ATGCTACAGG GCAAGCCGCT GGCCGACACG ATGCGTCCTG ACACGCTGCA GGATTACTTC 
GGGCAGAGCA AGGCCGTGGG CCAGGATACC CTGCTGCGCT CGCTCCTGGA GACCAACGAA 
ATCCCCTCGC TTATCCTGTG GGGGCCGCCG GGCTGCGGCA AGACCACTCT GGCTCACATC 
ATAGCCAGCA ACAGCAAGAA ACATAGCATA AGGTTTGTGA CATTATCTGC AACAAATGCC 
AAGACAAATG ATGTGCGAGA TGTCATAAAA CAAGCTCAAA ATGAAAAGAG CTTTTTCAAA 
AGGAAAACCA TCCTTTTTAT TGATGAGATT CATCGGTTCA ATAAATCTCA GCAGGTCAAC 
GCTGCTCTTC TGAGCCGCTG TCGAGTGATT GTTCTTGAGA AGCTTCCAGT AGAGGCAATG 
GTGACTATTT TAATGCGAGC GATCAACTCC CTGGGAATCC ACGTCCTAGA CTCTAGCCGT 
CCCACTGACC CTCTGAGCCA CAGCAGCAAC AGCAGCTCAG AGCCCGCCAT GTTCATAGAG 
GATAAAGCAG TAGACACCCT GGCTTACCTC AGTGACGGTG ACGCCCGAGC TGGGTTGAAC 
GGACTGCAGC TGGCGGTGCT GGCTAGGTTA AGCTCTAGGA AGATGTTCTG TAAGAAGAGT 
GGGCAATCCT ATTCTCCCAG TAGAGTTCTG ATCACAGAGA ATGACGTGAA GGAGGGCCTA 
CAGCGATCCC ACATTTTATA TGACCGGGCA GGTGAGGAGC ATTACAACTG CATCTCCGCC 
CTGCACAAGT CCATGCGGGG CTCAGACCAG AACGCCTCCC TCTACTGGCT GGCTCGCATG 
CTCGAGGGAG GAGAGGACCC ACTCTACGTG GCACGGAGGC TTGTCAGGTT TGCCAGCGAG 
GACATAGGTC TGGCAGACCC GTCTGCGTTA ACACAAGCGG TTGCTGCCTA CCAAGGCTGT 
CATTTTATAG GCATGCCTGA ATGTGAGGTG CTTCTGGCCC AGTGTGTGGT CTACTTTGCC 
AGAGCCCCAA AGTCCATTGA GGTGTACAGC GCCTACAACA ACGTCAAAGC CTGCCTGAGG 
AACCACCAGG GGCCACTGCC CCCCGTGCCC CTGCACCTGA GGAACGCGCC CACTAGGCTG 
ATGAAGGATT TGGGCTATGG CAAAGGCTAC AAGTACAACC CCATGTACAG CGAGCCTGTG 
GATCAGGAGT ACCTGCCTGA AGAGTTGAGG GGGGTAGATT TCTTCAAGCA GAGGAGGTGC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

WRNIP1 ( NM_130395.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_569079.1 Homo sapiens WRN helicase interacting protein 1 (WRNIP1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu14044
Clone ID Related Accession (Same CDS sequence)	NM_130395.2 , NM_130395.3
Accession Version	NM_130395.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1923bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-30
Organism	Homo sapiens(human)
Product	ATPase WRNIP1 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL139092.12, AK315047.1 and BC018923.2. On May 31, 2019 this sequence version replaced NM_130395.2. Transcript Variant: This variant (2) utilizes a different acceptor splice site for an internal coding exon, compared to transcript variant 1. This variant maintains the same reading frame but encodes an isoform (2) which is 25 aa shorter than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC018923.2, AK315471.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGGTGA GCGGGCCGGA AGACGACCCC TTCCTTTCGC AGCTGCACCA GGTGCAGTGC 
CCCGTGTGCC AGCAGATGAT GCCCGCCGCG CACATCAACT CGCACCTGGA CCGCTGTCTG 
CTGCTCCACC CGGCGGGGCA CGCGGAGCCC GCGGCCGGGT CGCACCGCGC CGGGGAGCGG 
GCCAAGGGGC CCTCGCCGCC CGGCGCCAAG AGGCGGCGGC TGTCGGAGAG CTCGGCGCTG 
AAGCAGCCAG CCACCCCGAC GGCAGCCGAG AGCAGCGAGG GCGAGGGTGA GGAGGGCGAC 
GACGGCGGCG AGACCGAGAG CCGCGAGAGC TACGACGCGC CGCCCACACC CAGCGGCGCC 
CGCCTTATCC CCGACTTCCC GGTGGCCCGC TCCAGCAGCC CCGGGAGGAA GGGGTCGGGG 
AAGAGGCCGG CGGCCGCCGC CGCGGCGGGG AGCGCGTCTC CGCGCAGCTG GGACGAGGCG 
GAGGCGCAGG AGGAGGAGGA GGCCGTGGGC GACGGCGATG GCGACGGGGA CGCGGACGCG 
GACGGCGAGG ACGACCCGGG GCACTGGGAC GCGGACGCTG CCGAAGCCGC CACCGCCTTC 
GGGGCCAGTG GCGGGGGCCG CCCGCACCCC CGGGCGCTGG CTGCCGAGGA GATCCGACAG 
ATGCTACAGG GCAAGCCGCT GGCCGACACG ATGCGTCCTG ACACGCTGCA GGATTACTTC 
GGGCAGAGCA AGGCCGTGGG CCAGGATACC CTGCTGCGCT CGCTCCTGGA GACCAACGAA 
ATCCCCTCGC TTATCCTGTG GGGGCCGCCG GGCTGCGGCA AGACCACTCT GGCTCACATC 
ATAGCCAGCA ACAGCAAGAA ACATAGCATA AGGTTTGTGA CATTATCTGC AACAAATGCC 
AAGACAAATG ATGTGCGAGA TGTCATAAAA CAAGCTCAAA ATGAAAAGAG CTTTTTCAAA 
AGGAAAACCA TCCTTTTTAT TGATGAGATT CATCGGTTCA ATAAATCTCA GCAGGTCAAC 
GCTGCTCTTC TGAGCCGCTG TCGAGTGATT GTTCTTGAGA AGCTTCCAGT AGAGGCAATG 
GTGACTATTT TAATGCGAGC GATCAACTCC CTGGGAATCC ACGTCCTAGA CTCTAGCCGT 
CCCACTGACC CTCTGAGCCA CAGCAGCAAC AGCAGCTCAG AGCCCGCCAT GTTCATAGAG 
GATAAAGCAG TAGACACCCT GGCTTACCTC AGTGACGGTG ACGCCCGAGC TGGGTTGAAC 
GGACTGCAGC TGGCGGTGCT GGCTAGGTTA AGCTCTAGGA AGATGTTCTG TAAGAAGAGT 
GGGCAATCCT ATTCTCCCAG TAGAGTTCTG ATCACAGAGA ATGACGTGAA GGAGGGCCTA 
CAGCGATCCC ACATTTTATA TGACCGGGCA GGTGAGGAGC ATTACAACTG CATCTCCGCC 
CTGCACAAGT CCATGCGGGG CTCAGACCAG AACGCCTCCC TCTACTGGCT GGCTCGCATG 
CTCGAGGGAG GAGAGGACCC ACTCTACGTG GCACGGAGGC TTGTCAGGTT TGCCAGCGAG 
GACATAGGTC TGGCAGACCC GTCTGCGTTA ACACAAGCGG TTGCTGCCTA CCAAGGCTGT 
CATTTTATAG GCATGCCTGA ATGTGAGGTG CTTCTGGCCC AGTGTGTGGT CTACTTTGCC 
AGAGCCCCAA AGTCCATTGA GGTGTACAGC GCCTACAACA ACGTCAAAGC CTGCCTGAGG 
AACCACCAGG GGCCACTGCC CCCCGTGCCC CTGCACCTGA GGAACGCGCC CACTAGGCTG 
ATGAAGGATT TGGGCTATGG CAAAGGCTAC AAGTACAACC CCATGTACAG CGAGCCTGTG 
GATCAGGAGT ACCTGCCTGA AGAGTTGAGG GGGGTAGATT TCTTCAAGCA GAGGAGGTGC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_569079.1
CDS	231..2153
Translation	MEVSGPEDDPFLSQLHQVQCPVCQQMMPAAHINSHLDRCLLLHPAGHAEPAAGSHRAGERAKGPSPPGAKRRRLSESSALKQPATPTAAESSEGEGEEGDDGGETESRESYDAPPTPSGARLIPDFPVARSSSPGRKGSGKRPAAAAAAGSASPRSWDEAEAQEEEEAVGDGDGDGDADADGEDDPGHWDADAAEAATAFGASGGGRPHPRALAAEEIRQMLQGKPLADTMRPDTLQDYFGQSKAVGQDTLLRSLLETNEIPSLILWGPPGCGKTTLAHIIASNSKKHSIRFVTLSATNAKTNDVRDVIKQAQNEKSFFKRKTILFIDEIHRFNKSQQVNAALLSRCRVIVLEKLPVEAMVTILMRAINSLGIHVLDSSRPTDPLSHSSNSSSEPAMFIEDKAVDTLAYLSDGDARAGLNGLQLAVLARLSSRKMFCKKSGQSYSPSRVLITENDVKEGLQRSHILYDRAGEEHYNCISALHKSMRGSDQNASLYWLARMLEGGEDPLYVARRLVRFASEDIGLADPSALTQAVAAYQGCHFIGMPECEVLLAQCVVYFARAPKSIEVYSAYNNVKACLRNHQGPLPPVPLHLRNAPTRLMKDLGYGKGYKYNPMYSEPVDQEYLPEELRGVDFFKQRRC

Target ORF information:

RefSeq Version	NM_130395.3
Organism	Homo sapiens(human)
Definition	Homo sapiens WRN helicase interacting protein 1 (WRNIP1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_130395.3

ORF Insert Sequence:

ATGGAGGTGA GCGGGCCGGA AGACGACCCC TTCCTTTCGC AGCTGCACCA GGTGCAGTGC 
CCCGTGTGCC AGCAGATGAT GCCCGCCGCG CACATCAACT CGCACCTGGA CCGCTGTCTG 
CTGCTCCACC CGGCGGGGCA CGCGGAGCCC GCGGCCGGGT CGCACCGCGC CGGGGAGCGG 
GCCAAGGGGC CCTCGCCGCC CGGCGCCAAG AGGCGGCGGC TGTCGGAGAG CTCGGCGCTG 
AAGCAGCCAG CCACCCCGAC GGCAGCCGAG AGCAGCGAGG GCGAGGGTGA GGAGGGCGAC 
GACGGCGGCG AGACCGAGAG CCGCGAGAGC TACGACGCGC CGCCCACACC CAGCGGCGCC 
CGCCTTATCC CCGACTTCCC GGTGGCCCGC TCCAGCAGCC CCGGGAGGAA GGGGTCGGGG 
AAGAGGCCGG CGGCCGCCGC CGCGGCGGGG AGCGCGTCTC CGCGCAGCTG GGACGAGGCG 
GAGGCGCAGG AGGAGGAGGA GGCCGTGGGC GACGGCGATG GCGACGGGGA CGCGGACGCG 
GACGGCGAGG ACGACCCGGG GCACTGGGAC GCGGACGCTG CCGAAGCCGC CACCGCCTTC 
GGGGCCAGTG GCGGGGGCCG CCCGCACCCC CGGGCGCTGG CTGCCGAGGA GATCCGACAG 
ATGCTACAGG GCAAGCCGCT GGCCGACACG ATGCGTCCTG ACACGCTGCA GGATTACTTC 
GGGCAGAGCA AGGCCGTGGG CCAGGATACC CTGCTGCGCT CGCTCCTGGA GACCAACGAA 
ATCCCCTCGC TTATCCTGTG GGGGCCGCCG GGCTGCGGCA AGACCACTCT GGCTCACATC 
ATAGCCAGCA ACAGCAAGAA ACATAGCATA AGGTTTGTGA CATTATCTGC AACAAATGCC 
AAGACAAATG ATGTGCGAGA TGTCATAAAA CAAGCTCAAA ATGAAAAGAG CTTTTTCAAA 
AGGAAAACCA TCCTTTTTAT TGATGAGATT CATCGGTTCA ATAAATCTCA GCAGGTCAAC 
GCTGCTCTTC TGAGCCGCTG TCGAGTGATT GTTCTTGAGA AGCTTCCAGT AGAGGCAATG 
GTGACTATTT TAATGCGAGC GATCAACTCC CTGGGAATCC ACGTCCTAGA CTCTAGCCGT 
CCCACTGACC CTCTGAGCCA CAGCAGCAAC AGCAGCTCAG AGCCCGCCAT GTTCATAGAG 
GATAAAGCAG TAGACACCCT GGCTTACCTC AGTGACGGTG ACGCCCGAGC TGGGTTGAAC 
GGACTGCAGC TGGCGGTGCT GGCTAGGTTA AGCTCTAGGA AGATGTTCTG TAAGAAGAGT 
GGGCAATCCT ATTCTCCCAG TAGAGTTCTG ATCACAGAGA ATGACGTGAA GGAGGGCCTA 
CAGCGATCCC ACATTTTATA TGACCGGGCA GGTGAGGAGC ATTACAACTG CATCTCCGCC 
CTGCACAAGT CCATGCGGGG CTCAGACCAG AACGCCTCCC TCTACTGGCT GGCTCGCATG 
CTCGAGGGAG GAGAGGACCC ACTCTACGTG GCACGGAGGC TTGTCAGGTT TGCCAGCGAG 
GACATAGGTC TGGCAGACCC GTCTGCGTTA ACACAAGCGG TTGCTGCCTA CCAAGGCTGT 
CATTTTATAG GCATGCCTGA ATGTGAGGTG CTTCTGGCCC AGTGTGTGGT CTACTTTGCC 
AGAGCCCCAA AGTCCATTGA GGTGTACAGC GCCTACAACA ACGTCAAAGC CTGCCTGAGG 
AACCACCAGG GGCCACTGCC CCCCGTGCCC CTGCACCTGA GGAACGCGCC CACTAGGCTG 
ATGAAGGATT TGGGCTATGG CAAAGGCTAC AAGTACAACC CCATGTACAG CGAGCCTGTG 
GATCAGGAGT ACCTGCCTGA AGAGTTGAGG GGGGTAGATT TCTTCAAGCA GAGGAGGTGC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

WRNIP1 ( XM_005249232.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005249289.1 Homo sapiens WRN helicase interacting protein 1 (WRNIP1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu40386
Clone ID Related Accession (Same CDS sequence)	XM_005249232.3
Accession Version	XM_005249232.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1260bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	ATPase WRNIP1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced XM_005249232.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGGTGA GCGGGCCGGA AGACGACCCC TTCCTTTCGC AGCTGCACCA GGTGCAGTGC 
CCCGTGTGCC AGCAGATGAT GCCCGCCGCG CACATCAACT CGCACCTGGA CCGCTGTCTG 
CTGCTCCACC CGGCGGGGCA CGCGGAGCCC GCGGCCGGGT CGCACCGCGC CGGGGAGCGG 
GCCAAGGGGC CCTCGCCGCC CGGCGCCAAG AGGCGGCGGC TGTCGGAGAG CTCGGCGCTG 
AAGCAGCCAG CCACCCCGAC GGCAGCCGAG AGCAGCGAGG GCGAGGGTGA GGAGGGCGAC 
GACGGCGGCG AGACCGAGAG CCGCGAGAGC TACGACGCGC CGCCCACACC CAGCGGCGCC 
CGCCTTATCC CCGACTTCCC GGTGGCCCGC TCCAGCAGCC CCGGGAGGAA GGGGTCGGGG 
AAGAGGCCGG CGGCCGCCGC CGCGGCGGGG AGCGCGTCTC CGCGCAGCTG GGACGAGGCG 
GAGGCGCAGG AGGAGGAGGA GGCCGTGGGC GACGGCGATG GCGACGGGGA CGCGGACGCG 
GACGGCGAGG ACGACCCGGG GCACTGGGAC GCGGACGCTG CCGAAGCCGC CACCGCCTTC 
GGGGCCAGTG GCGGGGGCCG CCCGCACCCC CGGGCGCTGG CTGCCGAGGA GATCCGACAG 
ATGCTACAGG GCAAGCCGCT GGCCGACACG ATGCGTCCTG ACACGCTGCA GGATTACTTC 
GGGCAGAGCA AGGCCGTGGG CCAGGATACC CTGCTGCGCT CGCTCCTGGA GACCAACGAA 
ATCCCCTCGC TTATCCTGTG GGGGCCGCCG GGCTGCGGCA AGACCACTCT GGCTCACATC 
ATAGCCAGCA ACAGCAAGAA ACATAGCATA AGGTTTGTGA CATTATCTGC AACAAATGCC 
AAGACAAATG ATGTGCGAGA TGTCATAAAA CAAGCTCAAA ATGAAAAGAG CTTTTTCAAA 
AGGAAAACCA TCCTTTTTAT TGATGAGATT CATCGGTTCA ATAAATCTCA GCAGGACACT 
TTCCTTCCTC ACGTGGAATG TGGGACGATC ACTCTGATTG GGGCAACCAC TGAAAACCCT 
TCCTTCCAGG TCAACGCTGC TCTTCTGAGC CGCTGTCGAG TGATTGTTCT TGAGAAGCTT 
CCAGTAGAGG CAATGGTGAC TATTTTAATG CGAGCGATCA ACTCCCTGGG AATCCACGTC 
CTAGACTCTA GCCGTCCCAC TGACCCTCTG AGCCACAGCA GCAACAGCAG CTCAGAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005249289.1
CDS	283..1542
Translation	MEVSGPEDDPFLSQLHQVQCPVCQQMMPAAHINSHLDRCLLLHPAGHAEPAAGSHRAGERAKGPSPPGAKRRRLSESSALKQPATPTAAESSEGEGEEGDDGGETESRESYDAPPTPSGARLIPDFPVARSSSPGRKGSGKRPAAAAAAGSASPRSWDEAEAQEEEEAVGDGDGDGDADADGEDDPGHWDADAAEAATAFGASGGGRPHPRALAAEEIRQMLQGKPLADTMRPDTLQDYFGQSKAVGQDTLLRSLLETNEIPSLILWGPPGCGKTTLAHIIASNSKKHSIRFVTLSATNAKTNDVRDVIKQAQNEKSFFKRKTILFIDEIHRFNKSQQDTFLPHVECGTITLIGATTENPSFQVNAALLSRCRVIVLEKLPVEAMVTILMRAINSLGIHVLDSSRPTDPLSHSSNSSSE

Target ORF information:

RefSeq Version	XM_005249232.3
Organism	Homo sapiens(human)
Definition	Homo sapiens WRN helicase interacting protein 1 (WRNIP1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005249232.3

ORF Insert Sequence:

ATGGAGGTGA GCGGGCCGGA AGACGACCCC TTCCTTTCGC AGCTGCACCA GGTGCAGTGC 
CCCGTGTGCC AGCAGATGAT GCCCGCCGCG CACATCAACT CGCACCTGGA CCGCTGTCTG 
CTGCTCCACC CGGCGGGGCA CGCGGAGCCC GCGGCCGGGT CGCACCGCGC CGGGGAGCGG 
GCCAAGGGGC CCTCGCCGCC CGGCGCCAAG AGGCGGCGGC TGTCGGAGAG CTCGGCGCTG 
AAGCAGCCAG CCACCCCGAC GGCAGCCGAG AGCAGCGAGG GCGAGGGTGA GGAGGGCGAC 
GACGGCGGCG AGACCGAGAG CCGCGAGAGC TACGACGCGC CGCCCACACC CAGCGGCGCC 
CGCCTTATCC CCGACTTCCC GGTGGCCCGC TCCAGCAGCC CCGGGAGGAA GGGGTCGGGG 
AAGAGGCCGG CGGCCGCCGC CGCGGCGGGG AGCGCGTCTC CGCGCAGCTG GGACGAGGCG 
GAGGCGCAGG AGGAGGAGGA GGCCGTGGGC GACGGCGATG GCGACGGGGA CGCGGACGCG 
GACGGCGAGG ACGACCCGGG GCACTGGGAC GCGGACGCTG CCGAAGCCGC CACCGCCTTC 
GGGGCCAGTG GCGGGGGCCG CCCGCACCCC CGGGCGCTGG CTGCCGAGGA GATCCGACAG 
ATGCTACAGG GCAAGCCGCT GGCCGACACG ATGCGTCCTG ACACGCTGCA GGATTACTTC 
GGGCAGAGCA AGGCCGTGGG CCAGGATACC CTGCTGCGCT CGCTCCTGGA GACCAACGAA 
ATCCCCTCGC TTATCCTGTG GGGGCCGCCG GGCTGCGGCA AGACCACTCT GGCTCACATC 
ATAGCCAGCA ACAGCAAGAA ACATAGCATA AGGTTTGTGA CATTATCTGC AACAAATGCC 
AAGACAAATG ATGTGCGAGA TGTCATAAAA CAAGCTCAAA ATGAAAAGAG CTTTTTCAAA 
AGGAAAACCA TCCTTTTTAT TGATGAGATT CATCGGTTCA ATAAATCTCA GCAGGACACT 
TTCCTTCCTC ACGTGGAATG TGGGACGATC ACTCTGATTG GGGCAACCAC TGAAAACCCT 
TCCTTCCAGG TCAACGCTGC TCTTCTGAGC CGCTGTCGAG TGATTGTTCT TGAGAAGCTT 
CCAGTAGAGG CAATGGTGAC TATTTTAATG CGAGCGATCA ACTCCCTGGG AATCCACGTC 
CTAGACTCTA GCCGTCCCAC TGACCCTCTG AGCCACAGCA GCAACAGCAG CTCAGAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

WRNIP1 ( XM_017011060.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016866549.1 Homo sapiens WRN helicase interacting protein 1 (WRNIP1), transcript variant X1, mRNA.

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CloneID	OHu96692
Clone ID Related Accession (Same CDS sequence)	XM_017011060.1
Accession Version	XM_017011060.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1317bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	ATPase WRNIP1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGGTGA GCGGGCCGGA AGACGACCCC TTCCTTTCGC AGCTGCACCA GGTGCAGTGC 
CCCGTGTGCC AGCAGATGAT GCCCGCCGCG CACATCAACT CGCACCTGGA CCGCTGTCTG 
CTGCTCCACC CGGCGGGGCA CGCGGAGCCC GCGGCCGGGT CGCACCGCGC CGGGGAGCGG 
GCCAAGGGGC CCTCGCCGCC CGGCGCCAAG AGGCGGCGGC TGTCGGAGAG CTCGGCGCTG 
AAGCAGCCAG CCACCCCGAC GGCAGCCGAG AGCAGCGAGG GCGAGGGTGA GGAGGGCGAC 
GACGGCGGCG AGACCGAGAG CCGCGAGAGC TACGACGCGC CGCCCACACC CAGCGGCGCC 
CGCCTTATCC CCGACTTCCC GGTGGCCCGC TCCAGCAGCC CCGGGAGGAA GGGGTCGGGG 
AAGAGGCCGG CGGCCGCCGC CGCGGCGGGG AGCGCGTCTC CGCGCAGCTG GGACGAGGCG 
GAGGCGCAGG AGGAGGAGGA GGCCGTGGGC GACGGCGATG GCGACGGGGA CGCGGACGCG 
GACGGCGAGG ACGACCCGGG GCACTGGGAC GCGGACGCTG CCGAAGCCGC CACCGCCTTC 
GGGGCCAGTG GCGGGGGCCG CCCGCACCCC CGGGCGCTGG CTGCCGAGGA GATCCGACAG 
ATGCTACAGG GCAAGCCGCT GGCCGACACG ATGCGTCCTG ACACGCTGCA GGATTACTTC 
GGGCAGAGCA AGGCCGTGGG CCAGGATACC CTGCTGCGCT CGCTCCTGGA GACCAACGAA 
ATCCCCTCGC TTATCCTGTG GGGGCCGCCG GGCTGCGGCA AGACCACTCT GGCTCACATC 
ATAGCCAGCA ACAGCAAGAA ACATAGCATA AGGTTTGTGA CATTATCTGC AACAAATGCC 
AAGACAAATG ATGTGCGAGA TGTCATAAAA CAAGCTCAAA ATGAAAAGAG CTTTTTCAAA 
AGGAAAACCA TCCTTTTTAT TGATGAGATT CATCGGTTCA ATAAATCTCA GCAGGACACT 
TTCCTTCCTC ACGTGGAATG TGGGACGATC ACTCTGATTG GGGCAACCAC TGAAAACCCT 
TCCTTCCAGG TCAACGCTGC TCTTCTGAGC CGCTGTCGAG TGATTGTTCT TGAGAAGCTT 
CCAGTAGAGG CAATGGTGAC TATTTTAATG CGAGCGATCA ACTCCCTGGG AATCCACGTC 
CTAGACTCTA GCCGTCCCAC TGACCCTCTG AGCCACAGCA GCAACAGCAG CTCAGAGAAG 
CTATTGGTGT GCATTTGTAT TCTTGTGTCA TGTTTTGGTG CCCTAGATAG CAACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016866549.1
CDS	283..1599
Translation	MEVSGPEDDPFLSQLHQVQCPVCQQMMPAAHINSHLDRCLLLHPAGHAEPAAGSHRAGERAKGPSPPGAKRRRLSESSALKQPATPTAAESSEGEGEEGDDGGETESRESYDAPPTPSGARLIPDFPVARSSSPGRKGSGKRPAAAAAAGSASPRSWDEAEAQEEEEAVGDGDGDGDADADGEDDPGHWDADAAEAATAFGASGGGRPHPRALAAEEIRQMLQGKPLADTMRPDTLQDYFGQSKAVGQDTLLRSLLETNEIPSLILWGPPGCGKTTLAHIIASNSKKHSIRFVTLSATNAKTNDVRDVIKQAQNEKSFFKRKTILFIDEIHRFNKSQQDTFLPHVECGTITLIGATTENPSFQVNAALLSRCRVIVLEKLPVEAMVTILMRAINSLGIHVLDSSRPTDPLSHSSNSSSEKLLVCICILVSCFGALDSN

Target ORF information:

RefSeq Version	XM_017011060.1
Organism	Homo sapiens(human)
Definition	Homo sapiens WRN helicase interacting protein 1 (WRNIP1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017011060.1

ORF Insert Sequence:

ATGGAGGTGA GCGGGCCGGA AGACGACCCC TTCCTTTCGC AGCTGCACCA GGTGCAGTGC 
CCCGTGTGCC AGCAGATGAT GCCCGCCGCG CACATCAACT CGCACCTGGA CCGCTGTCTG 
CTGCTCCACC CGGCGGGGCA CGCGGAGCCC GCGGCCGGGT CGCACCGCGC CGGGGAGCGG 
GCCAAGGGGC CCTCGCCGCC CGGCGCCAAG AGGCGGCGGC TGTCGGAGAG CTCGGCGCTG 
AAGCAGCCAG CCACCCCGAC GGCAGCCGAG AGCAGCGAGG GCGAGGGTGA GGAGGGCGAC 
GACGGCGGCG AGACCGAGAG CCGCGAGAGC TACGACGCGC CGCCCACACC CAGCGGCGCC 
CGCCTTATCC CCGACTTCCC GGTGGCCCGC TCCAGCAGCC CCGGGAGGAA GGGGTCGGGG 
AAGAGGCCGG CGGCCGCCGC CGCGGCGGGG AGCGCGTCTC CGCGCAGCTG GGACGAGGCG 
GAGGCGCAGG AGGAGGAGGA GGCCGTGGGC GACGGCGATG GCGACGGGGA CGCGGACGCG 
GACGGCGAGG ACGACCCGGG GCACTGGGAC GCGGACGCTG CCGAAGCCGC CACCGCCTTC 
GGGGCCAGTG GCGGGGGCCG CCCGCACCCC CGGGCGCTGG CTGCCGAGGA GATCCGACAG 
ATGCTACAGG GCAAGCCGCT GGCCGACACG ATGCGTCCTG ACACGCTGCA GGATTACTTC 
GGGCAGAGCA AGGCCGTGGG CCAGGATACC CTGCTGCGCT CGCTCCTGGA GACCAACGAA 
ATCCCCTCGC TTATCCTGTG GGGGCCGCCG GGCTGCGGCA AGACCACTCT GGCTCACATC 
ATAGCCAGCA ACAGCAAGAA ACATAGCATA AGGTTTGTGA CATTATCTGC AACAAATGCC 
AAGACAAATG ATGTGCGAGA TGTCATAAAA CAAGCTCAAA ATGAAAAGAG CTTTTTCAAA 
AGGAAAACCA TCCTTTTTAT TGATGAGATT CATCGGTTCA ATAAATCTCA GCAGGACACT 
TTCCTTCCTC ACGTGGAATG TGGGACGATC ACTCTGATTG GGGCAACCAC TGAAAACCCT 
TCCTTCCAGG TCAACGCTGC TCTTCTGAGC CGCTGTCGAG TGATTGTTCT TGAGAAGCTT 
CCAGTAGAGG CAATGGTGAC TATTTTAATG CGAGCGATCA ACTCCCTGGG AATCCACGTC 
CTAGACTCTA GCCGTCCCAC TGACCCTCTG AGCCACAGCA GCAACAGCAG CTCAGAGAAG 
CTATTGGTGT GCATTTGTAT TCTTGTGTCA TGTTTTGGTG CCCTAGATAG CAACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Assembly of the WHIP-TRIM14-PPP6C Mitochondrial Complex Promotes RIG-I-Mediated Antiviral Signaling.
Molecular cell68(2)293-307.e5(2017 Oct)
Tan P,He L,Cui J,Qian C,Cao X,Lin M,Zhu Q,Li Y,Xing C,Yu X,Wang HY,Wang RF

WRNIP1 protects stalled forks from degradation and promotes fork restart after replication stress.
The EMBO journal35(13)1437-51(2016 07)
Leuzzi G,Marabitti V,Pichierri P,Franchitto A

RAD18, WRNIP1 and ATMIN promote ATM signalling in response to replication stress.
Oncogene35(30)4009-19(2016 Jul)
Kanu N,Zhang T,Burrell RA,Chakraborty A,Cronshaw J,DaCosta C,Gr?nroos E,Pemberton HN,Anderton E,Gonzalez L,Sabbioneda S,Ulrich HD,Swanton C,Behrens A

A novel mode of ubiquitin recognition by the ubiquitin-binding zinc finger domain of WRNIP1.
The FEBS journal283(11)2004-17(2016 06)
Suzuki N,Rohaim A,Kato R,Dikic I,Wakatsuki S,Kawasaki M

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WRNIP1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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