EMC7 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	EMC7
Entrez Gene ID	56851
Full Name	ER membrane protein complex subunit 7
Synonyms	C11orf3,C15orf24,HT022,ORF1-FL1
General protein information	Preferred Names ER membrane protein complex subunit 7 Names ER membrane protein complex subunit 7 UPF0480 protein C15orf24 chromosome 15 hypothetical ATG/GTP binding protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 15 Map Location: 15q14

mRNA and Protein(s)

mRNA	Protein	Name
NM_020154.2	NP_064539.1	ER membrane protein complex subunit 7 precursor
NM_020154.3	NP_064539.1	ER membrane protein complex subunit 7 precursor

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	EMC7	XP_005638245.1
Mus musculus (house mouse)	Emc7	NP_598510.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP004626	XP_315192.4
Bos taurus (cattle)	EMC7	NP_001092613.1
Pan troglodytes (chimpanzee)	EMC7	XP_003952674.1
	LOC695440	XP_001085740.2
Gallus gallus (chicken)	C5H15ORF24	XP_421207.3
Homo sapiens (human)	EMC7	NP_064539.1
Rattus norvegicus (Norway rat)	RGD1305045	NP_001099966.1
Drosophila melanogaster (fruit fly)	CG8397	NP_611078.1
Danio rerio (zebrafish)	emc7	NP_001020686.1
Caenorhabditis elegans (roundworm)	C35D10.1	NP_001033353.1
Xenopus tropicalis (tropical clawed frog)	emc7	NP_001072567.1

Gene Ontology
Bibliography

Related articles in PubMed

Defining human ERAD networks through an integrative mapping strategy.
Christianson JC, Olzmann JA, Shaler TA, Sowa ME, Bennett EJ, Richter CM, Tyler RE, Greenblatt EJ, Harper JW, Kopito RR
Nature cell biology14(1)93-105(2011 Nov)

[Familial hypertrophic cardiomyopathy--a case report].
Domal-Kwiatkowska D, Glanowska G, Smolik S, Wilczewski P, Mazurek U, Nowalany-Kozielska E, Fudal M, Wodniecki J
Kardiologia polska64(11)1287-91(2006 Nov)

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.
Clark HF, Gurney AL, Abaya E, Baker K, Baldwin D, Brush J, Chen J, Chow B, Chui C, Crowley C, Currell B, Deuel B, Dowd P, Eaton D, Foster J, Grimaldi C, Gu Q, Hass PE, Heldens S, Huang A, Kim HS, Klimowski L, Jin Y, Johnson S, Lee J, Lewis L, Liao D, Mark M, Robbie E, Sanchez C, Schoenfeld J, Seshagiri S, Simmons L, Singh J, Smith V, Stinson J, Vagts A, Vandlen R, Watanabe C, Wieand D, Woods K, Xie MH, Yansura D, Yi S, Yu G, Yuan J, Zhang M, Zhang Z, Goddard A, Wood WI, Godowski P, Gray A
Genome research13(10)2265-70(2003 Oct)

Characterization of five novel human genes in the 11q13-q22 region.
O'Brien KP, Tapia-P?ez I, St?hle-B?ckdahl M, Kedra D, Dumanski JP
Biochemical and biophysical research communications273(1)90-4(2000 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Candidate modifier gene on the phenotypic expression of hypertrophy in patients with hyperthophic cardiomyopathy.
Title: [Familial hypertrophic cardiomyopathy--a case report].

The following EMC7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the EMC7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu03193	NM_020154.3 Latest version!	Homo sapiens ER membrane protein complex subunit 7 (EMC7), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu03193	NM_020154.2	Homo sapiens ER membrane protein complex subunit 7 (EMC7), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

EMC7 ( NM_020154.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_064539.1 Homo sapiens ER membrane protein complex subunit 7 (EMC7), mRNA.

Price & Availability↑

CloneID	OHu03193
Clone ID Related Accession (Same CDS sequence)	NM_020154.2 , NM_020154.3
Accession Version	NM_020154.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 729bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-30
Organism	Homo sapiens(human)
Product	ER membrane protein complex subunit 7 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AJ245874.1 and BC012456.1. On Dec 16, 2004 this sequence version replaced NM_020154.1. ##Evidence-Data-START## Transcript exon combination :: AJ250344.1, AY358445.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2142670 [ECO:0000348] ##Evidence-Data-END##

ATGGCGGCCG CTCTGTGGGG CTTCTTTCCC GTCCTGCTGC TGCTGCTGCT ATCGGGGGAT 
GTCCAGAGCT CGGAGGTGCC CGGGGCTGCT GCTGAGGGAT CGGGAGGGAG TGGGGTCGGC 
ATAGGAGATC GCTTCAAGAT TGAGGGGCGT GCAGTTGTTC CAGGGGTGAA GCCTCAGGAC 
TGGATCTCGG CGGCCCGAGT GCTGGTAGAC GGAGAAGAGC ACGTCGGTTT CCTTAAGACA 
GATGGGAGTT TTGTGGTTCA TGATATACCT TCTGGATCTT ATGTAGTGGA AGTTGTATCT 
CCAGCTTACA GATTTGATCC CGTTCGAGTG GATATCACTT CGAAAGGAAA AATGAGAGCA 
AGATATGTGA ATTACATCAA AACATCAGAG GTTGTCAGAC TGCCCTATCC TCTCCAAATG 
AAATCTTCAG GTCCACCTTC TTACTTTATT AAAAGGGAAT CGTGGGGCTG GACAGACTTT 
CTAATGAACC CAATGGTTAT GATGATGGTT CTTCCTTTAT TGATATTTGT GCTTCTGCCT 
AAAGTGGTCA ACACAAGTGA TCCTGACATG AGACGGGAAA TGGAGCAGTC AATGAATATG 
CTGAATTCCA ACCATGAGTT GCCTGATGTT TCTGAGTTCA TGACAAGACT CTTCTCTTCA 
AAATCATCTG GCAAATCTAG CAGCGGCAGC AGTAAAACAG GCAAAAGTGG GGCTGGCAAA 
AGGAGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_064539.1
CDS	14..742
Translation	MAAALWGFFPVLLLLLLSGDVQSSEVPGAAAEGSGGSGVGIGDRFKIEGRAVVPGVKPQDWISAARVLVDGEEHVGFLKTDGSFVVHDIPSGSYVVEVVSPAYRFDPVRVDITSKGKMRARYVNYIKTSEVVRLPYPLQMKSSGPPSYFIKRESWGWTDFLMNPMVMMMVLPLLIFVLLPKVVNTSDPDMRREMEQSMNMLNSNHELPDVSEFMTRLFSSKSSGKSSSGSSKTGKSGAGKRR

Target ORF information:

RefSeq Version	NM_020154.2
Organism	Homo sapiens(human)
Definition	Homo sapiens ER membrane protein complex subunit 7 (EMC7), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_020154.2

ORF Insert Sequence:

ATGGCGGCCG CTCTGTGGGG CTTCTTTCCC GTCCTGCTGC TGCTGCTGCT ATCGGGGGAT 
GTCCAGAGCT CGGAGGTGCC CGGGGCTGCT GCTGAGGGAT CGGGAGGGAG TGGGGTCGGC 
ATAGGAGATC GCTTCAAGAT TGAGGGGCGT GCAGTTGTTC CAGGGGTGAA GCCTCAGGAC 
TGGATCTCGG CGGCCCGAGT GCTGGTAGAC GGAGAAGAGC ACGTCGGTTT CCTTAAGACA 
GATGGGAGTT TTGTGGTTCA TGATATACCT TCTGGATCTT ATGTAGTGGA AGTTGTATCT 
CCAGCTTACA GATTTGATCC CGTTCGAGTG GATATCACTT CGAAAGGAAA AATGAGAGCA 
AGATATGTGA ATTACATCAA AACATCAGAG GTTGTCAGAC TGCCCTATCC TCTCCAAATG 
AAATCTTCAG GTCCACCTTC TTACTTTATT AAAAGGGAAT CGTGGGGCTG GACAGACTTT 
CTAATGAACC CAATGGTTAT GATGATGGTT CTTCCTTTAT TGATATTTGT GCTTCTGCCT 
AAAGTGGTCA ACACAAGTGA TCCTGACATG AGACGGGAAA TGGAGCAGTC AATGAATATG 
CTGAATTCCA ACCATGAGTT GCCTGATGTT TCTGAGTTCA TGACAAGACT CTTCTCTTCA 
AAATCATCTG GCAAATCTAG CAGCGGCAGC AGTAAAACAG GCAAAAGTGG GGCTGGCAAA 
AGGAGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EMC7 ( NM_020154.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_064539.1 Homo sapiens ER membrane protein complex subunit 7 (EMC7), mRNA.

Price & Availability↑

CloneID	OHu03193
Clone ID Related Accession (Same CDS sequence)	NM_020154.2 , NM_020154.3
Accession Version	NM_020154.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 729bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-01
Organism	Homo sapiens(human)
Product	ER membrane protein complex subunit 7 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC079203.9, AJ245874.1, BC012456.1 and AC069045.11. On Nov 22, 2018 this sequence version replaced NM_020154.2. ##Evidence-Data-START## Transcript exon combination :: AY358445.1, SRR5189655.179690.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142670, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000256545.9/ ENSP00000256545.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGGCCG CTCTGTGGGG CTTCTTTCCC GTCCTGCTGC TGCTGCTGCT ATCGGGGGAT 
GTCCAGAGCT CGGAGGTGCC CGGGGCTGCT GCTGAGGGAT CGGGAGGGAG TGGGGTCGGC 
ATAGGAGATC GCTTCAAGAT TGAGGGGCGT GCAGTTGTTC CAGGGGTGAA GCCTCAGGAC 
TGGATCTCGG CGGCCCGAGT GCTGGTAGAC GGAGAAGAGC ACGTCGGTTT CCTTAAGACA 
GATGGGAGTT TTGTGGTTCA TGATATACCT TCTGGATCTT ATGTAGTGGA AGTTGTATCT 
CCAGCTTACA GATTTGATCC CGTTCGAGTG GATATCACTT CGAAAGGAAA AATGAGAGCA 
AGATATGTGA ATTACATCAA AACATCAGAG GTTGTCAGAC TGCCCTATCC TCTCCAAATG 
AAATCTTCAG GTCCACCTTC TTACTTTATT AAAAGGGAAT CGTGGGGCTG GACAGACTTT 
CTAATGAACC CAATGGTTAT GATGATGGTT CTTCCTTTAT TGATATTTGT GCTTCTGCCT 
AAAGTGGTCA ACACAAGTGA TCCTGACATG AGACGGGAAA TGGAGCAGTC AATGAATATG 
CTGAATTCCA ACCATGAGTT GCCTGATGTT TCTGAGTTCA TGACAAGACT CTTCTCTTCA 
AAATCATCTG GCAAATCTAG CAGCGGCAGC AGTAAAACAG GCAAAAGTGG GGCTGGCAAA 
AGGAGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_064539.1
CDS	24..752
Translation	MAAALWGFFPVLLLLLLSGDVQSSEVPGAAAEGSGGSGVGIGDRFKIEGRAVVPGVKPQDWISAARVLVDGEEHVGFLKTDGSFVVHDIPSGSYVVEVVSPAYRFDPVRVDITSKGKMRARYVNYIKTSEVVRLPYPLQMKSSGPPSYFIKRESWGWTDFLMNPMVMMMVLPLLIFVLLPKVVNTSDPDMRREMEQSMNMLNSNHELPDVSEFMTRLFSSKSSGKSSSGSSKTGKSGAGKRR

Target ORF information:

RefSeq Version	NM_020154.3
Organism	Homo sapiens(human)
Definition	Homo sapiens ER membrane protein complex subunit 7 (EMC7), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_020154.3

ORF Insert Sequence:

ATGGCGGCCG CTCTGTGGGG CTTCTTTCCC GTCCTGCTGC TGCTGCTGCT ATCGGGGGAT 
GTCCAGAGCT CGGAGGTGCC CGGGGCTGCT GCTGAGGGAT CGGGAGGGAG TGGGGTCGGC 
ATAGGAGATC GCTTCAAGAT TGAGGGGCGT GCAGTTGTTC CAGGGGTGAA GCCTCAGGAC 
TGGATCTCGG CGGCCCGAGT GCTGGTAGAC GGAGAAGAGC ACGTCGGTTT CCTTAAGACA 
GATGGGAGTT TTGTGGTTCA TGATATACCT TCTGGATCTT ATGTAGTGGA AGTTGTATCT 
CCAGCTTACA GATTTGATCC CGTTCGAGTG GATATCACTT CGAAAGGAAA AATGAGAGCA 
AGATATGTGA ATTACATCAA AACATCAGAG GTTGTCAGAC TGCCCTATCC TCTCCAAATG 
AAATCTTCAG GTCCACCTTC TTACTTTATT AAAAGGGAAT CGTGGGGCTG GACAGACTTT 
CTAATGAACC CAATGGTTAT GATGATGGTT CTTCCTTTAT TGATATTTGT GCTTCTGCCT 
AAAGTGGTCA ACACAAGTGA TCCTGACATG AGACGGGAAA TGGAGCAGTC AATGAATATG 
CTGAATTCCA ACCATGAGTT GCCTGATGTT TCTGAGTTCA TGACAAGACT CTTCTCTTCA 
AAATCATCTG GCAAATCTAG CAGCGGCAGC AGTAAAACAG GCAAAAGTGG GGCTGGCAAA 
AGGAGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Defining human ERAD networks through an integrative mapping strategy.
Nature cell biology14(1)93-105(2011 Nov)
Christianson JC,Olzmann JA,Shaler TA,Sowa ME,Bennett EJ,Richter CM,Tyler RE,Greenblatt EJ,Harper JW,Kopito RR

[Familial hypertrophic cardiomyopathy--a case report].
Kardiologia polska64(11)1287-91(2006 Nov)
Domal-Kwiatkowska D,Glanowska G,Smolik S,Wilczewski P,Mazurek U,Nowalany-Kozielska E,Fudal M,Wodniecki J

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.
Genome research13(10)2265-70(2003 Oct)
Clark HF,Gurney AL,Abaya E,Baker K,Baldwin D,Brush J,Chen J,Chow B,Chui C,Crowley C,Currell B,Deuel B,Dowd P,Eaton D,Foster J,Grimaldi C,Gu Q,Hass PE,Heldens S,Huang A,Kim HS,Klimowski L,Jin Y,Johnson S,Lee J,Lewis L,Liao D,Mark M,Robbie E,Sanchez C,Schoenfeld J,Seshagiri S,Simmons L,Singh J,Smith V,Stinson J,Vagts A,Vandlen R,Watanabe C,Wieand D,Woods K,Xie MH,Yansura D,Yi S,Yu G,Yuan J,Zhang M,Zhang Z,Goddard A,Wood WI,Godowski P,Gray A

Characterization of five novel human genes in the 11q13-q22 region.
Biochemical and biophysical research communications273(1)90-4(2000 Jun)
O'Brien KP,Tapia-P?ez I,St?hle-B?ckdahl M,Kedra D,Dumanski JP

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EMC7 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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