BCCIP cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	BCCIP
Entrez Gene ID	56647
Full Name	BRCA2 and CDKN1A interacting protein
Synonyms	TOK-1,TOK1
General protein information	Preferred Names BRCA2 and CDKN1A interacting protein Names BRCA2 and CDKN1A-interacting protein BCCIPalpha BCCIPbeta BRCA2 and Cip1/p21 interacting protein TOK-1alpha TOK-1beta cdk inhibitor p21 binding protein p21- and CDK-associated protein 1 protein TOK-1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 10 Map Location: 10q26.2
Summary	This gene product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21. This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].
Disorder MIM:	611883

mRNA and Protein(s)

mRNA	Protein	Name
NM_078469.3	NP_510869.1	BRCA2 and CDKN1A-interacting protein isoform C
NM_016567.4	NP_057651.1	BRCA2 and CDKN1A-interacting protein isoform BCCIPalpha
NM_078468.3	NP_510868.1	BRCA2 and CDKN1A-interacting protein isoform BCCIPbeta
NM_078469.2	NP_510869.1	BRCA2 and CDKN1A-interacting protein isoform C
NM_016567.3	NP_057651.1	BRCA2 and CDKN1A-interacting protein isoform BCCIPalpha
NM_078468.2	NP_510868.1	BRCA2 and CDKN1A-interacting protein isoform BCCIPbeta

Pathways from BioSystems

Homologies

Homo sapiens (human)	BCCIP	NP_510868.1
	BCCIP	XP_001087888.2
Drosophila melanogaster (fruit fly)	CG9286	NP_650317.3
Pan troglodytes (chimpanzee)	BCCIP	XP_003312867.1
Rattus norvegicus (Norway rat)	Bccip	NP_001101975.2
Gallus gallus (chicken)	BCCIP	XP_423888.1
Canis lupus familiaris (dog)	BCCIP	XP_535056.2
Bos taurus (cattle)	BCCIP	NP_001039587.1
Mus musculus (house mouse)	Bccip	NP_079668.2
Danio rerio (zebrafish)	bccip	NP_001013493.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP003476	XP_311766.3
Xenopus tropicalis (tropical clawed frog)	bccip	NP_001004968.1

Gene Ontology
Bibliography

Related articles in PubMed

Roles of BCCIP deficiency in mammary tumorigenesis.
Droz-Rosario R, Lu H, Liu J, Liu NA, Ganesan S, Xia B, Haffty BG, Shen Z
Breast cancer research : BCR19(1)115(2017 Oct)

The non-canonical poly(A) polymerase FAM46C acts as an onco-suppressor in multiple myeloma.
Mroczek S, Chlebowska J, Kuli?ski TM, Gewartowska O, Gruchota J, Cysewski D, Liudkovska V, Borsuk E, Nowis D, Dziembowski A
Nature communications8(1)619(2017 09)

Regulation of spindle integrity and mitotic fidelity by BCCIP.
Huhn SC, Liu J, Ye C, Lu H, Jiang X, Feng X, Ganesan S, White E, Shen Z
Oncogene36(33)4750-4766(2017 Aug)

BCCIP? modulates the ribosomal and extraribosomal function of S7 through a direct interaction.
Ba Q, Li X, Huang C, Li J, Fu Y, Chen P, Duan J, Hao M, Zhang Y, Li J, Sun C, Ying H, Song H, Zhang R, Shen Z, Wang H
Journal of molecular cell biology9(3)209-219(2017 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

this study identifies BCCIP as a novel factor critical for microtubule regulation and explicates a mechanism utilized by BCCIP in tumor suppression.
Title: Regulation of spindle integrity and mitotic fidelity by BCCIP.

Expression of BCCIP beta was notably higher in tumor tissues of esophageal squamous cell carcinoma (ESCC) and Eca 109 cells. In vitro studies such as starvation and refeeding assay along with BCCIP beta-shRNA transfection assay demonstrated that BCCIP beta expression promoted proliferation of ESCC cells.
Title: High Expression of BCCIP ? Can Promote Proliferation of Esophageal Squamous Cell Carcinoma.

we demonstrate that BCCIPbeta induces a conformational change within the RAD51 filament that promotes release of ADP to help maintain an active presynaptic filament. Our findings reveal a functional role for BCCIPbeta as a RAD51 accessory factor in HR.
Title: The ?-isoform of BCCIP promotes ADP release from the RAD51 presynaptic filament and enhances homologous DNA pairing.

the existence of both INO80 and YY1 is required for recruiting the INO80/YY1 complex to BCCIP promoter region. Our findings strongly indicate that BCCIP is a potential target gene of the INO80/YY1 complex.
Title: Human INO80/YY1 chromatin remodeling complex transcriptionally regulates the BRCA2- and CDKN1A-interacting protein (BCCIP) in cells.

The BCCIPbeta, but not BCCIPalpha, interacts with EIF6 and RPL23/UL14 and stabilizes the latter.
Title: The beta-isoform of the BRCA2 and CDKN1A(p21)-interacting protein (BCCIP) stabilizes nuclear RPL23/uL14.

The following BCCIP gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the BCCIP cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu18441	NM_016567.4 Latest version!	Homo sapiens BRCA2 and CDKN1A interacting protein (BCCIP), transcript variant A, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
OHu29154	NM_078469.3 Latest version!	Homo sapiens BRCA2 and CDKN1A interacting protein (BCCIP), transcript variant C, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$216.30 $309.00
OHu31552	NM_078468.3 Latest version!	Homo sapiens BRCA2 and CDKN1A interacting protein (BCCIP), transcript variant B, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$216.30 $309.00
View Old Accession Versions >>
OHu29154	NM_078469.2	Homo sapiens BRCA2 and CDKN1A interacting protein (BCCIP), transcript variant C, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$216.30 $309.00
OHu18441	NM_016567.3	Homo sapiens BRCA2 and CDKN1A interacting protein (BCCIP), transcript variant A, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
OHu31552	NM_078468.2	Homo sapiens BRCA2 and CDKN1A interacting protein (BCCIP), transcript variant B, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$216.30 $309.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

BCCIP ( NM_016567.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_057651.1 Homo sapiens BRCA2 and CDKN1A interacting protein (BCCIP), transcript variant A, mRNA.

Price & Availability↑

CloneID	OHu18441
Clone ID Related Accession (Same CDS sequence)	NM_016567.4 , NM_016567.3
Accession Version	NM_016567.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 969bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-03
Organism	Homo sapiens(human)
Product	BRCA2 and CDKN1A-interacting protein isoform BCCIPalpha
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY064248.1 and BM974496.1. This sequence is a reference standard in the RefSeqGene project. On May 31, 2019 this sequence version replaced NM_016567.3. Transcript Variant: This variant (A) encodes the longest isoform (BCCIPalpha, which is also known as TOK-1alpha). BCCIPalpha has a different C-terminus compared to isoforms BCCIPbeta and C, and has been the subject of most functional studies. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DRR138524.1291095.1, SRR1163658.28018.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGTCCA GGTCTAAGCG GCGTGCCGTG GAAAGTGGGG TTCCGCAGCC GCCGGATCCC 
CCAGTCCAGC GCGACGAGGA AGAGGAAAAA GAAGTCGAAA ATGAGGATGA AGACGATGAT 
GACAGTGACA AGGAAAAGGA TGAAGAGGAC GAGGTCATTG ACGAGGAAGT GAATATTGAA 
TTTGAAGCTT ATTCCCTATC AGATAATGAT TATGACGGAA TTAAGAAATT ACTGCAGCAG 
CTTTTTCTAA AGGCTCCTGT GAACACTGCA GAACTAACAG ATCTCTTAAT TCAACAGAAC 
CATATTGGGA GTGTGATTAA GCAAACGGAT GTTTCAGAAG ACAGCAATGA TGATATGGAT 
GAAGATGAGG TTTTTGGTTT CATAAGCCTT TTAAATTTAA CTGAAAGAAA GGGTACCCAG 
TGTGTTGAAC AAATTCAAGA GTTGGTTCTA CGCTTCTGTG AGAAGAACTG TGAAAAGAGC 
ATGGTTGAAC AGCTGGACAA GTTTTTAAAT GACACCACCA AGCCTGTGGG CCTTCTCCTA 
AGTGAAAGAT TCATTAATGT CCCTCCACAG ATCGCTCTGC CCATGTACCA GCAGCTTCAG 
AAAGAACTGG CGGGGGCACA CAGAACCAAT AAGCCATGTG GGAAGTGCTA CTTTTACCTT 
CTGATTAGTA AGACATTTGT GGAAGCAGGA AAAAACAATT CCAAAAAGAA ACCTAGCAAC 
AAAAAGAAAG CTGCGTTAAT GTTTGCAAAT GCAGAGGAAG AATTTTTCTA TGAGGAGCAG 
GGAAAACCTG AGGTGCTTGG AGGTCCAGAC ACAAGAAGAG GATTGGAACC AGTTCCGATA 
CAGCACAATG GTGGTTCACG GGGGCAAGTG ACAGCCCTGG TTTCTCTGAA GGCTGGACTA 
ATTCAATCAA GATCAACTCT AAGTGATTTC CAGGGAACCT TCATGACTGT TGGAATTGCT 
CTGTCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057651.1
CDS	13..981
Translation	MASRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMDEDEVFGFISLLNLTERKGTQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLLSERFINVPPQIALPMYQQLQKELAGAHRTNKPCGKCYFYLLISKTFVEAGKNNSKKKPSNKKKAALMFANAEEEFFYEEQGKPEVLGGPDTRRGLEPVPIQHNGGSRGQVTALVSLKAGLIQSRSTLSDFQGTFMTVGIALS

Target ORF information:

RefSeq Version	NM_016567.4
Organism	Homo sapiens(human)
Definition	Homo sapiens BRCA2 and CDKN1A interacting protein (BCCIP), transcript variant A, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016567.4

ORF Insert Sequence:

ATGGCGTCCA GGTCTAAGCG GCGTGCCGTG GAAAGTGGGG TTCCGCAGCC GCCGGATCCC 
CCAGTCCAGC GCGACGAGGA AGAGGAAAAA GAAGTCGAAA ATGAGGATGA AGACGATGAT 
GACAGTGACA AGGAAAAGGA TGAAGAGGAC GAGGTCATTG ACGAGGAAGT GAATATTGAA 
TTTGAAGCTT ATTCCCTATC AGATAATGAT TATGACGGAA TTAAGAAATT ACTGCAGCAG 
CTTTTTCTAA AGGCTCCTGT GAACACTGCA GAACTAACAG ATCTCTTAAT TCAACAGAAC 
CATATTGGGA GTGTGATTAA GCAAACGGAT GTTTCAGAAG ACAGCAATGA TGATATGGAT 
GAAGATGAGG TTTTTGGTTT CATAAGCCTT TTAAATTTAA CTGAAAGAAA GGGTACCCAG 
TGTGTTGAAC AAATTCAAGA GTTGGTTCTA CGCTTCTGTG AGAAGAACTG TGAAAAGAGC 
ATGGTTGAAC AGCTGGACAA GTTTTTAAAT GACACCACCA AGCCTGTGGG CCTTCTCCTA 
AGTGAAAGAT TCATTAATGT CCCTCCACAG ATCGCTCTGC CCATGTACCA GCAGCTTCAG 
AAAGAACTGG CGGGGGCACA CAGAACCAAT AAGCCATGTG GGAAGTGCTA CTTTTACCTT 
CTGATTAGTA AGACATTTGT GGAAGCAGGA AAAAACAATT CCAAAAAGAA ACCTAGCAAC 
AAAAAGAAAG CTGCGTTAAT GTTTGCAAAT GCAGAGGAAG AATTTTTCTA TGAGGAGCAG 
GGAAAACCTG AGGTGCTTGG AGGTCCAGAC ACAAGAAGAG GATTGGAACC AGTTCCGATA 
CAGCACAATG GTGGTTCACG GGGGCAAGTG ACAGCCCTGG TTTCTCTGAA GGCTGGACTA 
ATTCAATCAA GATCAACTCT AAGTGATTTC CAGGGAACCT TCATGACTGT TGGAATTGCT 
CTGTCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BCCIP ( NM_016567.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_057651.1 Homo sapiens BRCA2 and CDKN1A interacting protein (BCCIP), transcript variant A, mRNA.

Price & Availability↑

CloneID	OHu18441
Clone ID Related Accession (Same CDS sequence)	NM_016567.4 , NM_016567.3
Accession Version	NM_016567.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 969bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-17
Organism	Homo sapiens(human)
Product	BRCA2 and CDKN1A-interacting protein isoform BCCIPalpha
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY064248.1 and BM974496.1. This sequence is a reference standard in the RefSeqGene project. On Mar 12, 2008 this sequence version replaced NM_016567.2. Transcript Variant: This variant (A) encodes the longest isoform (BCCIPalpha, which is also known as TOK-1alpha). BCCIPalpha has a different C-terminus compared to isoforms BCCIPbeta and C, and has been the subject of most functional studies. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.28018.1, SRR1163658.342437.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGTCCA GGTCTAAGCG GCGTGCCGTG GAAAGTGGGG TTCCGCAGCC GCCGGATCCC 
CCAGTCCAGC GCGACGAGGA AGAGGAAAAA GAAGTCGAAA ATGAGGATGA AGACGATGAT 
GACAGTGACA AGGAAAAGGA TGAAGAGGAC GAGGTCATTG ACGAGGAAGT GAATATTGAA 
TTTGAAGCTT ATTCCCTATC AGATAATGAT TATGACGGAA TTAAGAAATT ACTGCAGCAG 
CTTTTTCTAA AGGCTCCTGT GAACACTGCA GAACTAACAG ATCTCTTAAT TCAACAGAAC 
CATATTGGGA GTGTGATTAA GCAAACGGAT GTTTCAGAAG ACAGCAATGA TGATATGGAT 
GAAGATGAGG TTTTTGGTTT CATAAGCCTT TTAAATTTAA CTGAAAGAAA GGGTACCCAG 
TGTGTTGAAC AAATTCAAGA GTTGGTTCTA CGCTTCTGTG AGAAGAACTG TGAAAAGAGC 
ATGGTTGAAC AGCTGGACAA GTTTTTAAAT GACACCACCA AGCCTGTGGG CCTTCTCCTA 
AGTGAAAGAT TCATTAATGT CCCTCCACAG ATCGCTCTGC CCATGTACCA GCAGCTTCAG 
AAAGAACTGG CGGGGGCACA CAGAACCAAT AAGCCATGTG GGAAGTGCTA CTTTTACCTT 
CTGATTAGTA AGACATTTGT GGAAGCAGGA AAAAACAATT CCAAAAAGAA ACCTAGCAAC 
AAAAAGAAAG CTGCGTTAAT GTTTGCAAAT GCAGAGGAAG AATTTTTCTA TGAGGAGCAG 
GGAAAACCTG AGGTGCTTGG AGGTCCAGAC ACAAGAAGAG GATTGGAACC AGTTCCGATA 
CAGCACAATG GTGGTTCACG GGGGCAAGTG ACAGCCCTGG TTTCTCTGAA GGCTGGACTA 
ATTCAATCAA GATCAACTCT AAGTGATTTC CAGGGAACCT TCATGACTGT TGGAATTGCT 
CTGTCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_057651.1
CDS	24..992
Translation	MASRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMDEDEVFGFISLLNLTERKGTQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLLSERFINVPPQIALPMYQQLQKELAGAHRTNKPCGKCYFYLLISKTFVEAGKNNSKKKPSNKKKAALMFANAEEEFFYEEQGKPEVLGGPDTRRGLEPVPIQHNGGSRGQVTALVSLKAGLIQSRSTLSDFQGTFMTVGIALS

Target ORF information:

RefSeq Version	NM_016567.3
Organism	Homo sapiens(human)
Definition	Homo sapiens BRCA2 and CDKN1A interacting protein (BCCIP), transcript variant A, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_016567.3

ORF Insert Sequence:

ATGGCGTCCA GGTCTAAGCG GCGTGCCGTG GAAAGTGGGG TTCCGCAGCC GCCGGATCCC 
CCAGTCCAGC GCGACGAGGA AGAGGAAAAA GAAGTCGAAA ATGAGGATGA AGACGATGAT 
GACAGTGACA AGGAAAAGGA TGAAGAGGAC GAGGTCATTG ACGAGGAAGT GAATATTGAA 
TTTGAAGCTT ATTCCCTATC AGATAATGAT TATGACGGAA TTAAGAAATT ACTGCAGCAG 
CTTTTTCTAA AGGCTCCTGT GAACACTGCA GAACTAACAG ATCTCTTAAT TCAACAGAAC 
CATATTGGGA GTGTGATTAA GCAAACGGAT GTTTCAGAAG ACAGCAATGA TGATATGGAT 
GAAGATGAGG TTTTTGGTTT CATAAGCCTT TTAAATTTAA CTGAAAGAAA GGGTACCCAG 
TGTGTTGAAC AAATTCAAGA GTTGGTTCTA CGCTTCTGTG AGAAGAACTG TGAAAAGAGC 
ATGGTTGAAC AGCTGGACAA GTTTTTAAAT GACACCACCA AGCCTGTGGG CCTTCTCCTA 
AGTGAAAGAT TCATTAATGT CCCTCCACAG ATCGCTCTGC CCATGTACCA GCAGCTTCAG 
AAAGAACTGG CGGGGGCACA CAGAACCAAT AAGCCATGTG GGAAGTGCTA CTTTTACCTT 
CTGATTAGTA AGACATTTGT GGAAGCAGGA AAAAACAATT CCAAAAAGAA ACCTAGCAAC 
AAAAAGAAAG CTGCGTTAAT GTTTGCAAAT GCAGAGGAAG AATTTTTCTA TGAGGAGCAG 
GGAAAACCTG AGGTGCTTGG AGGTCCAGAC ACAAGAAGAG GATTGGAACC AGTTCCGATA 
CAGCACAATG GTGGTTCACG GGGGCAAGTG ACAGCCCTGG TTTCTCTGAA GGCTGGACTA 
ATTCAATCAA GATCAACTCT AAGTGATTTC CAGGGAACCT TCATGACTGT TGGAATTGCT 
CTGTCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BCCIP ( NM_078469.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_510869.1 Homo sapiens BRCA2 and CDKN1A interacting protein (BCCIP), transcript variant C, mRNA.

Price & Availability↑

CloneID	OHu29154
Clone ID Related Accession (Same CDS sequence)	NM_078469.3 , NM_078469.2
Accession Version	NM_078469.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 879bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Homo sapiens(human)
Product	BRCA2 and CDKN1A-interacting protein isoform C
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BM905542.1, AL834458.1 and BM741863.1. On May 31, 2019 this sequence version replaced NM_078469.2. Transcript Variant: This variant (C) is alternatively spliced at the 3' end compared to transcript variant A. It encodes an isoform (C) which has the same 284 N-terminal aa, but is truncated at the C-terminus compared to isoform BCCIPalpha. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR5189655.115205.1, SRR1803616.207661.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGTCCA GGTCTAAGCG GCGTGCCGTG GAAAGTGGGG TTCCGCAGCC GCCGGATCCC 
CCAGTCCAGC GCGACGAGGA AGAGGAAAAA GAAGTCGAAA ATGAGGATGA AGACGATGAT 
GACAGTGACA AGGAAAAGGA TGAAGAGGAC GAGGTCATTG ACGAGGAAGT GAATATTGAA 
TTTGAAGCTT ATTCCCTATC AGATAATGAT TATGACGGAA TTAAGAAATT ACTGCAGCAG 
CTTTTTCTAA AGGCTCCTGT GAACACTGCA GAACTAACAG ATCTCTTAAT TCAACAGAAC 
CATATTGGGA GTGTGATTAA GCAAACGGAT GTTTCAGAAG ACAGCAATGA TGATATGGAT 
GAAGATGAGG TTTTTGGTTT CATAAGCCTT TTAAATTTAA CTGAAAGAAA GGGTACCCAG 
TGTGTTGAAC AAATTCAAGA GTTGGTTCTA CGCTTCTGTG AGAAGAACTG TGAAAAGAGC 
ATGGTTGAAC AGCTGGACAA GTTTTTAAAT GACACCACCA AGCCTGTGGG CCTTCTCCTA 
AGTGAAAGAT TCATTAATGT CCCTCCACAG ATCGCTCTGC CCATGTACCA GCAGCTTCAG 
AAAGAACTGG CGGGGGCACA CAGAACCAAT AAGCCATGTG GGAAGTGCTA CTTTTACCTT 
CTGATTAGTA AGACATTTGT GGAAGCAGGA AAAAACAATT CCAAAAAGAA ACCTAGCAAC 
AAAAAGAAAG CTGCGTTAAT GTTTGCAAAT GCAGAGGAAG AATTTTTCTA TGAGGAGCAG 
GGAAAACCTG AGGTGCTTGG AGGTCCAGAC ACAAGAAGAG GATTGGAACC AGTTCCGATA 
CAGCACAATG GTTGGTCTGT TCCCCCAGTA TTAGAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_510869.1
CDS	13..891
Translation	MASRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMDEDEVFGFISLLNLTERKGTQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLLSERFINVPPQIALPMYQQLQKELAGAHRTNKPCGKCYFYLLISKTFVEAGKNNSKKKPSNKKKAALMFANAEEEFFYEEQGKPEVLGGPDTRRGLEPVPIQHNGWSVPPVLE

Target ORF information:

RefSeq Version	NM_078469.3
Organism	Homo sapiens(human)
Definition	Homo sapiens BRCA2 and CDKN1A interacting protein (BCCIP), transcript variant C, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_078469.3

ORF Insert Sequence:

ATGGCGTCCA GGTCTAAGCG GCGTGCCGTG GAAAGTGGGG TTCCGCAGCC GCCGGATCCC 
CCAGTCCAGC GCGACGAGGA AGAGGAAAAA GAAGTCGAAA ATGAGGATGA AGACGATGAT 
GACAGTGACA AGGAAAAGGA TGAAGAGGAC GAGGTCATTG ACGAGGAAGT GAATATTGAA 
TTTGAAGCTT ATTCCCTATC AGATAATGAT TATGACGGAA TTAAGAAATT ACTGCAGCAG 
CTTTTTCTAA AGGCTCCTGT GAACACTGCA GAACTAACAG ATCTCTTAAT TCAACAGAAC 
CATATTGGGA GTGTGATTAA GCAAACGGAT GTTTCAGAAG ACAGCAATGA TGATATGGAT 
GAAGATGAGG TTTTTGGTTT CATAAGCCTT TTAAATTTAA CTGAAAGAAA GGGTACCCAG 
TGTGTTGAAC AAATTCAAGA GTTGGTTCTA CGCTTCTGTG AGAAGAACTG TGAAAAGAGC 
ATGGTTGAAC AGCTGGACAA GTTTTTAAAT GACACCACCA AGCCTGTGGG CCTTCTCCTA 
AGTGAAAGAT TCATTAATGT CCCTCCACAG ATCGCTCTGC CCATGTACCA GCAGCTTCAG 
AAAGAACTGG CGGGGGCACA CAGAACCAAT AAGCCATGTG GGAAGTGCTA CTTTTACCTT 
CTGATTAGTA AGACATTTGT GGAAGCAGGA AAAAACAATT CCAAAAAGAA ACCTAGCAAC 
AAAAAGAAAG CTGCGTTAAT GTTTGCAAAT GCAGAGGAAG AATTTTTCTA TGAGGAGCAG 
GGAAAACCTG AGGTGCTTGG AGGTCCAGAC ACAAGAAGAG GATTGGAACC AGTTCCGATA 
CAGCACAATG GTTGGTCTGT TCCCCCAGTA TTAGAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BCCIP ( NM_078469.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_510869.1 Homo sapiens BRCA2 and CDKN1A interacting protein (BCCIP), transcript variant C, mRNA.

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CloneID	OHu29154
Clone ID Related Accession (Same CDS sequence)	NM_078469.3 , NM_078469.2
Accession Version	NM_078469.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 879bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-17
Organism	Homo sapiens(human)
Product	BRCA2 and CDKN1A-interacting protein isoform C
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BM905542.1, AL834458.1, BM741863.1 and AA806484.1. On Mar 12, 2008 this sequence version replaced NM_078469.1. Transcript Variant: This variant (C) is alternatively spliced at the 3' end compared to transcript variant A. It encodes an isoform (C) which has the same 284 N-terminal aa, but is truncated at the C-terminus compared to isoform BCCIPalpha. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AL834458.1, AK055691.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGTCCA GGTCTAAGCG GCGTGCCGTG GAAAGTGGGG TTCCGCAGCC GCCGGATCCC 
CCAGTCCAGC GCGACGAGGA AGAGGAAAAA GAAGTCGAAA ATGAGGATGA AGACGATGAT 
GACAGTGACA AGGAAAAGGA TGAAGAGGAC GAGGTCATTG ACGAGGAAGT GAATATTGAA 
TTTGAAGCTT ATTCCCTATC AGATAATGAT TATGACGGAA TTAAGAAATT ACTGCAGCAG 
CTTTTTCTAA AGGCTCCTGT GAACACTGCA GAACTAACAG ATCTCTTAAT TCAACAGAAC 
CATATTGGGA GTGTGATTAA GCAAACGGAT GTTTCAGAAG ACAGCAATGA TGATATGGAT 
GAAGATGAGG TTTTTGGTTT CATAAGCCTT TTAAATTTAA CTGAAAGAAA GGGTACCCAG 
TGTGTTGAAC AAATTCAAGA GTTGGTTCTA CGCTTCTGTG AGAAGAACTG TGAAAAGAGC 
ATGGTTGAAC AGCTGGACAA GTTTTTAAAT GACACCACCA AGCCTGTGGG CCTTCTCCTA 
AGTGAAAGAT TCATTAATGT CCCTCCACAG ATCGCTCTGC CCATGTACCA GCAGCTTCAG 
AAAGAACTGG CGGGGGCACA CAGAACCAAT AAGCCATGTG GGAAGTGCTA CTTTTACCTT 
CTGATTAGTA AGACATTTGT GGAAGCAGGA AAAAACAATT CCAAAAAGAA ACCTAGCAAC 
AAAAAGAAAG CTGCGTTAAT GTTTGCAAAT GCAGAGGAAG AATTTTTCTA TGAGGAGCAG 
GGAAAACCTG AGGTGCTTGG AGGTCCAGAC ACAAGAAGAG GATTGGAACC AGTTCCGATA 
CAGCACAATG GTTGGTCTGT TCCCCCAGTA TTAGAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_510869.1
CDS	24..902
Translation	MASRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMDEDEVFGFISLLNLTERKGTQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLLSERFINVPPQIALPMYQQLQKELAGAHRTNKPCGKCYFYLLISKTFVEAGKNNSKKKPSNKKKAALMFANAEEEFFYEEQGKPEVLGGPDTRRGLEPVPIQHNGWSVPPVLE

Target ORF information:

RefSeq Version	NM_078469.2
Organism	Homo sapiens(human)
Definition	Homo sapiens BRCA2 and CDKN1A interacting protein (BCCIP), transcript variant C, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_078469.2

ORF Insert Sequence:

ATGGCGTCCA GGTCTAAGCG GCGTGCCGTG GAAAGTGGGG TTCCGCAGCC GCCGGATCCC 
CCAGTCCAGC GCGACGAGGA AGAGGAAAAA GAAGTCGAAA ATGAGGATGA AGACGATGAT 
GACAGTGACA AGGAAAAGGA TGAAGAGGAC GAGGTCATTG ACGAGGAAGT GAATATTGAA 
TTTGAAGCTT ATTCCCTATC AGATAATGAT TATGACGGAA TTAAGAAATT ACTGCAGCAG 
CTTTTTCTAA AGGCTCCTGT GAACACTGCA GAACTAACAG ATCTCTTAAT TCAACAGAAC 
CATATTGGGA GTGTGATTAA GCAAACGGAT GTTTCAGAAG ACAGCAATGA TGATATGGAT 
GAAGATGAGG TTTTTGGTTT CATAAGCCTT TTAAATTTAA CTGAAAGAAA GGGTACCCAG 
TGTGTTGAAC AAATTCAAGA GTTGGTTCTA CGCTTCTGTG AGAAGAACTG TGAAAAGAGC 
ATGGTTGAAC AGCTGGACAA GTTTTTAAAT GACACCACCA AGCCTGTGGG CCTTCTCCTA 
AGTGAAAGAT TCATTAATGT CCCTCCACAG ATCGCTCTGC CCATGTACCA GCAGCTTCAG 
AAAGAACTGG CGGGGGCACA CAGAACCAAT AAGCCATGTG GGAAGTGCTA CTTTTACCTT 
CTGATTAGTA AGACATTTGT GGAAGCAGGA AAAAACAATT CCAAAAAGAA ACCTAGCAAC 
AAAAAGAAAG CTGCGTTAAT GTTTGCAAAT GCAGAGGAAG AATTTTTCTA TGAGGAGCAG 
GGAAAACCTG AGGTGCTTGG AGGTCCAGAC ACAAGAAGAG GATTGGAACC AGTTCCGATA 
CAGCACAATG GTTGGTCTGT TCCCCCAGTA TTAGAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BCCIP ( NM_078468.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_510868.1 Homo sapiens BRCA2 and CDKN1A interacting protein (BCCIP), transcript variant B, mRNA.

Price & Availability↑

CloneID	OHu31552
Clone ID Related Accession (Same CDS sequence)	NM_078468.3 , NM_078468.2
Accession Version	NM_078468.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 945bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	BRCA2 and CDKN1A-interacting protein isoform BCCIPbeta
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY064249.1. On Nov 22, 2018 this sequence version replaced NM_078468.2. Transcript Variant: This variant (B) is alternatively spliced at the 3' end compared to transcript variant A. It encodes an isoform (BCCIPbeta) which has the same 258 N-terminal aa, but a different C-terminus compared to isoform BCCIPalpha. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY064249.1, BC009771.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000278100.11/ ENSP00000278100.6 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGTCCA GGTCTAAGCG GCGTGCCGTG GAAAGTGGGG TTCCGCAGCC GCCGGATCCC 
CCAGTCCAGC GCGACGAGGA AGAGGAAAAA GAAGTCGAAA ATGAGGATGA AGACGATGAT 
GACAGTGACA AGGAAAAGGA TGAAGAGGAC GAGGTCATTG ACGAGGAAGT GAATATTGAA 
TTTGAAGCTT ATTCCCTATC AGATAATGAT TATGACGGAA TTAAGAAATT ACTGCAGCAG 
CTTTTTCTAA AGGCTCCTGT GAACACTGCA GAACTAACAG ATCTCTTAAT TCAACAGAAC 
CATATTGGGA GTGTGATTAA GCAAACGGAT GTTTCAGAAG ACAGCAATGA TGATATGGAT 
GAAGATGAGG TTTTTGGTTT CATAAGCCTT TTAAATTTAA CTGAAAGAAA GGGTACCCAG 
TGTGTTGAAC AAATTCAAGA GTTGGTTCTA CGCTTCTGTG AGAAGAACTG TGAAAAGAGC 
ATGGTTGAAC AGCTGGACAA GTTTTTAAAT GACACCACCA AGCCTGTGGG CCTTCTCCTA 
AGTGAAAGAT TCATTAATGT CCCTCCACAG ATCGCTCTGC CCATGTACCA GCAGCTTCAG 
AAAGAACTGG CGGGGGCACA CAGAACCAAT AAGCCATGTG GGAAGTGCTA CTTTTACCTT 
CTGATTAGTA AGACATTTGT GGAAGCAGGA AAAAACAATT CCAAAAAGAA ACCTAGCAAC 
AAAAAGAAAG CTGCGTTAAT GTTTGCAAAT GCAGAGGAAG AATTTTTCTA TGAGAAGGCA 
ATTCTCAAGT TCAACTACTC AGTGCAGGAG GAGAGCGACA CTTGTCTGGG AGGCAAATGG 
TCTTTTGATG ACGTACCAAT GACGCCCTTG CGAACTGTGA TGTTAATTCC AGGCGACAAG 
ATGAACGAAA TCATGGATAA ACTGAAAGAA TATCTATCTG TCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_510868.1
CDS	13..957
Translation	MASRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMDEDEVFGFISLLNLTERKGTQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLLSERFINVPPQIALPMYQQLQKELAGAHRTNKPCGKCYFYLLISKTFVEAGKNNSKKKPSNKKKAALMFANAEEEFFYEKAILKFNYSVQEESDTCLGGKWSFDDVPMTPLRTVMLIPGDKMNEIMDKLKEYLSV

Target ORF information:

RefSeq Version	NM_078468.3
Organism	Homo sapiens(human)
Definition	Homo sapiens BRCA2 and CDKN1A interacting protein (BCCIP), transcript variant B, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_078468.3

ORF Insert Sequence:

ATGGCGTCCA GGTCTAAGCG GCGTGCCGTG GAAAGTGGGG TTCCGCAGCC GCCGGATCCC 
CCAGTCCAGC GCGACGAGGA AGAGGAAAAA GAAGTCGAAA ATGAGGATGA AGACGATGAT 
GACAGTGACA AGGAAAAGGA TGAAGAGGAC GAGGTCATTG ACGAGGAAGT GAATATTGAA 
TTTGAAGCTT ATTCCCTATC AGATAATGAT TATGACGGAA TTAAGAAATT ACTGCAGCAG 
CTTTTTCTAA AGGCTCCTGT GAACACTGCA GAACTAACAG ATCTCTTAAT TCAACAGAAC 
CATATTGGGA GTGTGATTAA GCAAACGGAT GTTTCAGAAG ACAGCAATGA TGATATGGAT 
GAAGATGAGG TTTTTGGTTT CATAAGCCTT TTAAATTTAA CTGAAAGAAA GGGTACCCAG 
TGTGTTGAAC AAATTCAAGA GTTGGTTCTA CGCTTCTGTG AGAAGAACTG TGAAAAGAGC 
ATGGTTGAAC AGCTGGACAA GTTTTTAAAT GACACCACCA AGCCTGTGGG CCTTCTCCTA 
AGTGAAAGAT TCATTAATGT CCCTCCACAG ATCGCTCTGC CCATGTACCA GCAGCTTCAG 
AAAGAACTGG CGGGGGCACA CAGAACCAAT AAGCCATGTG GGAAGTGCTA CTTTTACCTT 
CTGATTAGTA AGACATTTGT GGAAGCAGGA AAAAACAATT CCAAAAAGAA ACCTAGCAAC 
AAAAAGAAAG CTGCGTTAAT GTTTGCAAAT GCAGAGGAAG AATTTTTCTA TGAGAAGGCA 
ATTCTCAAGT TCAACTACTC AGTGCAGGAG GAGAGCGACA CTTGTCTGGG AGGCAAATGG 
TCTTTTGATG ACGTACCAAT GACGCCCTTG CGAACTGTGA TGTTAATTCC AGGCGACAAG 
ATGAACGAAA TCATGGATAA ACTGAAAGAA TATCTATCTG TCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BCCIP ( NM_078468.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_510868.1 Homo sapiens BRCA2 and CDKN1A interacting protein (BCCIP), transcript variant B, mRNA.

Price & Availability↑

CloneID	OHu31552
Clone ID Related Accession (Same CDS sequence)	NM_078468.3 , NM_078468.2
Accession Version	NM_078468.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 945bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-15
Organism	Homo sapiens(human)
Product	BRCA2 and CDKN1A-interacting protein isoform BCCIPbeta
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY064249.1 and BQ008485.1. On Mar 12, 2008 this sequence version replaced NM_078468.1. Transcript Variant: This variant (B) is alternatively spliced at the 3' end compared to transcript variant A. It encodes an isoform (BCCIPbeta) which has the same 258 N-terminal aa, but a different C-terminus compared to isoform BCCIPalpha. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY064249.1, BC009771.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGTCCA GGTCTAAGCG GCGTGCCGTG GAAAGTGGGG TTCCGCAGCC GCCGGATCCC 
CCAGTCCAGC GCGACGAGGA AGAGGAAAAA GAAGTCGAAA ATGAGGATGA AGACGATGAT 
GACAGTGACA AGGAAAAGGA TGAAGAGGAC GAGGTCATTG ACGAGGAAGT GAATATTGAA 
TTTGAAGCTT ATTCCCTATC AGATAATGAT TATGACGGAA TTAAGAAATT ACTGCAGCAG 
CTTTTTCTAA AGGCTCCTGT GAACACTGCA GAACTAACAG ATCTCTTAAT TCAACAGAAC 
CATATTGGGA GTGTGATTAA GCAAACGGAT GTTTCAGAAG ACAGCAATGA TGATATGGAT 
GAAGATGAGG TTTTTGGTTT CATAAGCCTT TTAAATTTAA CTGAAAGAAA GGGTACCCAG 
TGTGTTGAAC AAATTCAAGA GTTGGTTCTA CGCTTCTGTG AGAAGAACTG TGAAAAGAGC 
ATGGTTGAAC AGCTGGACAA GTTTTTAAAT GACACCACCA AGCCTGTGGG CCTTCTCCTA 
AGTGAAAGAT TCATTAATGT CCCTCCACAG ATCGCTCTGC CCATGTACCA GCAGCTTCAG 
AAAGAACTGG CGGGGGCACA CAGAACCAAT AAGCCATGTG GGAAGTGCTA CTTTTACCTT 
CTGATTAGTA AGACATTTGT GGAAGCAGGA AAAAACAATT CCAAAAAGAA ACCTAGCAAC 
AAAAAGAAAG CTGCGTTAAT GTTTGCAAAT GCAGAGGAAG AATTTTTCTA TGAGAAGGCA 
ATTCTCAAGT TCAACTACTC AGTGCAGGAG GAGAGCGACA CTTGTCTGGG AGGCAAATGG 
TCTTTTGATG ACGTACCAAT GACGCCCTTG CGAACTGTGA TGTTAATTCC AGGCGACAAG 
ATGAACGAAA TCATGGATAA ACTGAAAGAA TATCTATCTG TCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_510868.1
CDS	24..968
Translation	MASRSKRRAVESGVPQPPDPPVQRDEEEEKEVENEDEDDDDSDKEKDEEDEVIDEEVNIEFEAYSLSDNDYDGIKKLLQQLFLKAPVNTAELTDLLIQQNHIGSVIKQTDVSEDSNDDMDEDEVFGFISLLNLTERKGTQCVEQIQELVLRFCEKNCEKSMVEQLDKFLNDTTKPVGLLLSERFINVPPQIALPMYQQLQKELAGAHRTNKPCGKCYFYLLISKTFVEAGKNNSKKKPSNKKKAALMFANAEEEFFYEKAILKFNYSVQEESDTCLGGKWSFDDVPMTPLRTVMLIPGDKMNEIMDKLKEYLSV

Target ORF information:

RefSeq Version	NM_078468.2
Organism	Homo sapiens(human)
Definition	Homo sapiens BRCA2 and CDKN1A interacting protein (BCCIP), transcript variant B, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_078468.2

ORF Insert Sequence:

ATGGCGTCCA GGTCTAAGCG GCGTGCCGTG GAAAGTGGGG TTCCGCAGCC GCCGGATCCC 
CCAGTCCAGC GCGACGAGGA AGAGGAAAAA GAAGTCGAAA ATGAGGATGA AGACGATGAT 
GACAGTGACA AGGAAAAGGA TGAAGAGGAC GAGGTCATTG ACGAGGAAGT GAATATTGAA 
TTTGAAGCTT ATTCCCTATC AGATAATGAT TATGACGGAA TTAAGAAATT ACTGCAGCAG 
CTTTTTCTAA AGGCTCCTGT GAACACTGCA GAACTAACAG ATCTCTTAAT TCAACAGAAC 
CATATTGGGA GTGTGATTAA GCAAACGGAT GTTTCAGAAG ACAGCAATGA TGATATGGAT 
GAAGATGAGG TTTTTGGTTT CATAAGCCTT TTAAATTTAA CTGAAAGAAA GGGTACCCAG 
TGTGTTGAAC AAATTCAAGA GTTGGTTCTA CGCTTCTGTG AGAAGAACTG TGAAAAGAGC 
ATGGTTGAAC AGCTGGACAA GTTTTTAAAT GACACCACCA AGCCTGTGGG CCTTCTCCTA 
AGTGAAAGAT TCATTAATGT CCCTCCACAG ATCGCTCTGC CCATGTACCA GCAGCTTCAG 
AAAGAACTGG CGGGGGCACA CAGAACCAAT AAGCCATGTG GGAAGTGCTA CTTTTACCTT 
CTGATTAGTA AGACATTTGT GGAAGCAGGA AAAAACAATT CCAAAAAGAA ACCTAGCAAC 
AAAAAGAAAG CTGCGTTAAT GTTTGCAAAT GCAGAGGAAG AATTTTTCTA TGAGAAGGCA 
ATTCTCAAGT TCAACTACTC AGTGCAGGAG GAGAGCGACA CTTGTCTGGG AGGCAAATGG 
TCTTTTGATG ACGTACCAAT GACGCCCTTG CGAACTGTGA TGTTAATTCC AGGCGACAAG 
ATGAACGAAA TCATGGATAA ACTGAAAGAA TATCTATCTG TCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Roles of BCCIP deficiency in mammary tumorigenesis.
Breast cancer research : BCR19(1)115(2017 Oct)
Droz-Rosario R,Lu H,Liu J,Liu NA,Ganesan S,Xia B,Haffty BG,Shen Z

The non-canonical poly(A) polymerase FAM46C acts as an onco-suppressor in multiple myeloma.
Nature communications8(1)619(2017 09)
Mroczek S,Chlebowska J,Kuli?ski TM,Gewartowska O,Gruchota J,Cysewski D,Liudkovska V,Borsuk E,Nowis D,Dziembowski A

Regulation of spindle integrity and mitotic fidelity by BCCIP.
Oncogene36(33)4750-4766(2017 Aug)
Huhn SC,Liu J,Ye C,Lu H,Jiang X,Feng X,Ganesan S,White E,Shen Z

BCCIP? modulates the ribosomal and extraribosomal function of S7 through a direct interaction.
Journal of molecular cell biology9(3)209-219(2017 Jun)
Ba Q,Li X,Huang C,Li J,Fu Y,Chen P,Duan J,Hao M,Zhang Y,Li J,Sun C,Ying H,Song H,Zhang R,Shen Z,Wang H

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BCCIP cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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