Gene Symbol | ASAH2 |
Entrez Gene ID | 56624 |
Full Name | N-acylsphingosine amidohydrolase 2 |
Synonyms | BCDase,HNAC1,LCDase,N-CDase,NCDase |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | Ceramidases (EC 3.5.1.23), such as ASAH2, catalyze hydrolysis of the N-acyl linkage of ceramide, a second messenger in a variety of cellular events, to produce sphingosine. Sphingosine exerts both mitogenic and apoptosis-inducing activities, and its phosphorylated form functions as an intra- and intercellular second messenger (see MIM 603730) (Mitsutake et al., 2001 [PubMed 11328816]).[supplied by OMIM, Mar 2008]. |
Disorder MIM: |