DIABLO gene cDNA ORF clone, Homo sapiens(human)

mRNA	Protein	Name
NM_001278304.1	NP_001265233.1	diablo homolog, mitochondrial isoform 2
NM_019887.5	NP_063940.1	diablo homolog, mitochondrial isoform 1 precursor
NM_001278302.1	NP_001265231.1	diablo homolog, mitochondrial isoform 4
NM_001278303.1	NP_001265232.1	diablo homolog, mitochondrial isoform 5
NM_001278304.2	NP_001265233.1	diablo homolog, mitochondrial isoform 2
NM_019887.6	NP_063940.1	diablo homolog, mitochondrial isoform 1 precursor
NM_001278342.1	NP_001265271.1	diablo homolog, mitochondrial isoform 3
NM_138930.3	NP_620308.1	diablo homolog, mitochondrial isoform 2
NM_001371333.1	NP_001358262.1	diablo homolog, mitochondrial isoform 1 precursor

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu27556	NM_001278303.1 Latest version!	Homo sapiens diablo IAP-binding mitochondrial protein (DIABLO), transcript variant 6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu27599	NM_019887.6 Latest version!	Homo sapiens diablo IAP-binding mitochondrial protein (DIABLO), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu27599	NM_001371333.1 Latest version!	Homo sapiens diablo IAP-binding mitochondrial protein (DIABLO), transcript variant 8, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu14896	NM_001278304.2 Latest version!	Homo sapiens diablo IAP-binding mitochondrial protein (DIABLO), transcript variant 7, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu14896	NM_138930.3 Latest version!	Homo sapiens diablo IAP-binding mitochondrial protein (DIABLO), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu27633	NM_001278302.1 Latest version!	Homo sapiens diablo IAP-binding mitochondrial protein (DIABLO), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu27641	NM_001278342.1 Latest version!	Homo sapiens diablo IAP-binding mitochondrial protein (DIABLO), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
View Old Accession Versions >>
OHu14896	NM_001278304.1	Homo sapiens diablo IAP-binding mitochondrial protein (DIABLO), transcript variant 7, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu27599	NM_019887.5	Homo sapiens diablo IAP-binding mitochondrial protein (DIABLO), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

DIABLO ( NM_001278303.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001265232.1 Homo sapiens diablo IAP-binding mitochondrial protein (DIABLO), transcript variant 6, mRNA.

Price & Availability↑

CloneID	OHu27556
Clone ID Related Accession (Same CDS sequence)	NM_001278303.1
Accession Version	NM_001278303.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 501bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-07
Organism	Homo sapiens(human)
Product	diablo homolog, mitochondrial isoform 5
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA877400.1, BC046209.1, BF313712.1, AK057778.1 and N66735.1. Transcript Variant: This variant (6) differs in the 5' UTR, lacks a portion of the 5' coding region, and uses a downstream in-frame start codon, compared to variant 1. The encoded isoform (5, also known as Smac-gamma) has a shorter N-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.122247.1, BE313731.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA2152798 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: PMID: 10929711; reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAGGAGAG CAGTGTCTTT GGTAACAGAT AGCACCTCTA CCTTTCTCTC TCAGACCACA 
TATGCGTTGA TTGAAGCTAT TACTGAATAT ACTAAGGCTG TTTATACCTT AACTTCTCTT 
TACCGACAAT ATACAAGTTT ACTTGGGAAA ATGAATTCAG AGGAGGAAGA TGAAGTGTGG 
CAGGTGATCA TAGGAGCCAG AGCTGAGATG ACTTCAAAAC ACCAAGAGTA CTTGAAGCTG 
GAAACCACTT GGATGACTGC AGTTGGTCTT TCAGAGATGG CAGCAGAAGC TGCATATCAA 
ACTGGCGCAG ATCAGGCCTC TATAACCGCC AGGAATCACA TTCAGCTGGT GAAACTGCAG 
GTGGAAGAGG TGCACCAGCT CTCCCGGAAA GCAGAAACCA AGCTGGCAGA AGCACAGATA 
GAAGAGCTCC GTCAGAAAAC ACAGGAGGAA GGGGAGGAGC GGGCTGAGTC GGAGCAGGAG 
GCCTACCTGC GTGAGGATTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001265232.1
CDS	641..1141
Translation	MRRAVSLVTDSTSTFLSQTTYALIEAITEYTKAVYTLTSLYRQYTSLLGKMNSEEEDEVWQVIIGARAEMTSKHQEYLKLETTWMTAVGLSEMAAEAAYQTGADQASITARNHIQLVKLQVEEVHQLSRKAETKLAEAQIEELRQKTQEEGEERAESEQEAYLRED

Target ORF information:

RefSeq Version	NM_001278303.1
Organism	Homo sapiens(human)
Definition	Homo sapiens diablo IAP-binding mitochondrial protein (DIABLO), transcript variant 6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001278303.1

ORF Insert Sequence:

ATGAGGAGAG CAGTGTCTTT GGTAACAGAT AGCACCTCTA CCTTTCTCTC TCAGACCACA 
TATGCGTTGA TTGAAGCTAT TACTGAATAT ACTAAGGCTG TTTATACCTT AACTTCTCTT 
TACCGACAAT ATACAAGTTT ACTTGGGAAA ATGAATTCAG AGGAGGAAGA TGAAGTGTGG 
CAGGTGATCA TAGGAGCCAG AGCTGAGATG ACTTCAAAAC ACCAAGAGTA CTTGAAGCTG 
GAAACCACTT GGATGACTGC AGTTGGTCTT TCAGAGATGG CAGCAGAAGC TGCATATCAA 
ACTGGCGCAG ATCAGGCCTC TATAACCGCC AGGAATCACA TTCAGCTGGT GAAACTGCAG 
GTGGAAGAGG TGCACCAGCT CTCCCGGAAA GCAGAAACCA AGCTGGCAGA AGCACAGATA 
GAAGAGCTCC GTCAGAAAAC ACAGGAGGAA GGGGAGGAGC GGGCTGAGTC GGAGCAGGAG 
GCCTACCTGC GTGAGGATTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DIABLO ( NM_019887.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_063940.1 Homo sapiens diablo IAP-binding mitochondrial protein (DIABLO), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu27599
Clone ID Related Accession (Same CDS sequence)	NM_019887.5 , NM_019887.6 , NM_001371333.1
Accession Version	NM_019887.5	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 720bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Homo sapiens(human)
Product	diablo homolog, mitochondrial isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA910387.1, DA915183.1, BC046209.1, AK057778.1 and N66735.1. This sequence is a reference standard in the RefSeqGene project. On May 29, 2013 this sequence version replaced NM_019887.4. Transcript Variant: This variant (1) encodes the longest isoform (1, also known as Smac-alpha). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC046209.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: downstream AUG is associated with N-terminal localization signal (PMID:10929711) gene product(s) localized to mito. :: PMID: 10929711; reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCTC TGAAGAGTTG GCTGTCGCGC AGCGTAACTT CATTCTTCAG GTACAGACAG 
TGTTTGTGTG TTCCTGTTGT GGCTAACTTT AAGAAGCGGT GTTTCTCAGA ATTGATAAGA 
CCATGGCACA AAACTGTGAC GATTGGCTTT GGAGTAACCC TGTGTGCGGT TCCTATTGCA 
CAGAAATCAG AGCCTCATTC CCTTAGTAGT GAAGCATTGA TGAGGAGAGC AGTGTCTTTG 
GTAACAGATA GCACCTCTAC CTTTCTCTCT CAGACCACAT ATGCGTTGAT TGAAGCTATT 
ACTGAATATA CTAAGGCTGT TTATACCTTA ACTTCTCTTT ACCGACAATA TACAAGTTTA 
CTTGGGAAAA TGAATTCAGA GGAGGAAGAT GAAGTGTGGC AGGTGATCAT AGGAGCCAGA 
GCTGAGATGA CTTCAAAACA CCAAGAGTAC TTGAAGCTGG AAACCACTTG GATGACTGCA 
GTTGGTCTTT CAGAGATGGC AGCAGAAGCT GCATATCAAA CTGGCGCAGA TCAGGCCTCT 
ATAACCGCCA GGAATCACAT TCAGCTGGTG AAACTGCAGG TGGAAGAGGT GCACCAGCTC 
TCCCGGAAAG CAGAAACCAA GCTGGCAGAA GCACAGATAG AAGAGCTCCG TCAGAAAACA 
CAGGAGGAAG GGGAGGAGCG GGCTGAGTCG GAGCAGGAGG CCTACCTGCG TGAGGATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_063940.1
CDS	819..1538
Translation	MAALKSWLSRSVTSFFRYRQCLCVPVVANFKKRCFSELIRPWHKTVTIGFGVTLCAVPIAQKSEPHSLSSEALMRRAVSLVTDSTSTFLSQTTYALIEAITEYTKAVYTLTSLYRQYTSLLGKMNSEEEDEVWQVIIGARAEMTSKHQEYLKLETTWMTAVGLSEMAAEAAYQTGADQASITARNHIQLVKLQVEEVHQLSRKAETKLAEAQIEELRQKTQEEGEERAESEQEAYLRED

Target ORF information:

RefSeq Version	NM_019887.5
Organism	Homo sapiens(human)
Definition	Homo sapiens diablo IAP-binding mitochondrial protein (DIABLO), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019887.5

ORF Insert Sequence:

ATGGCGGCTC TGAAGAGTTG GCTGTCGCGC AGCGTAACTT CATTCTTCAG GTACAGACAG 
TGTTTGTGTG TTCCTGTTGT GGCTAACTTT AAGAAGCGGT GTTTCTCAGA ATTGATAAGA 
CCATGGCACA AAACTGTGAC GATTGGCTTT GGAGTAACCC TGTGTGCGGT TCCTATTGCA 
CAGAAATCAG AGCCTCATTC CCTTAGTAGT GAAGCATTGA TGAGGAGAGC AGTGTCTTTG 
GTAACAGATA GCACCTCTAC CTTTCTCTCT CAGACCACAT ATGCGTTGAT TGAAGCTATT 
ACTGAATATA CTAAGGCTGT TTATACCTTA ACTTCTCTTT ACCGACAATA TACAAGTTTA 
CTTGGGAAAA TGAATTCAGA GGAGGAAGAT GAAGTGTGGC AGGTGATCAT AGGAGCCAGA 
GCTGAGATGA CTTCAAAACA CCAAGAGTAC TTGAAGCTGG AAACCACTTG GATGACTGCA 
GTTGGTCTTT CAGAGATGGC AGCAGAAGCT GCATATCAAA CTGGCGCAGA TCAGGCCTCT 
ATAACCGCCA GGAATCACAT TCAGCTGGTG AAACTGCAGG TGGAAGAGGT GCACCAGCTC 
TCCCGGAAAG CAGAAACCAA GCTGGCAGAA GCACAGATAG AAGAGCTCCG TCAGAAAACA 
CAGGAGGAAG GGGAGGAGCG GGCTGAGTCG GAGCAGGAGG CCTACCTGCG TGAGGATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DIABLO ( NM_019887.6 ) cDNA ORF clone, Homo sapiens(human) -> NP_063940.1 Homo sapiens diablo IAP-binding mitochondrial protein (DIABLO), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu27599
Clone ID Related Accession (Same CDS sequence)	NM_019887.5 , NM_019887.6 , NM_001371333.1
Accession Version	NM_019887.6 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 720bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-07
Organism	Homo sapiens(human)
Product	diablo homolog, mitochondrial isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA915183.1, BC046209.1, AK057778.1 and N66735.1. On Jun 2, 2019 this sequence version replaced NM_019887.5. Transcript Variant: This variant (1) encodes the longest isoform (1, also known as Smac-alpha). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC046209.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: downstream AUG is associated with N-terminal localization signal (PMID:10929711) gene product(s) localized to mito. :: PMID: 10929711; reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCTC TGAAGAGTTG GCTGTCGCGC AGCGTAACTT CATTCTTCAG GTACAGACAG 
TGTTTGTGTG TTCCTGTTGT GGCTAACTTT AAGAAGCGGT GTTTCTCAGA ATTGATAAGA 
CCATGGCACA AAACTGTGAC GATTGGCTTT GGAGTAACCC TGTGTGCGGT TCCTATTGCA 
CAGAAATCAG AGCCTCATTC CCTTAGTAGT GAAGCATTGA TGAGGAGAGC AGTGTCTTTG 
GTAACAGATA GCACCTCTAC CTTTCTCTCT CAGACCACAT ATGCGTTGAT TGAAGCTATT 
ACTGAATATA CTAAGGCTGT TTATACCTTA ACTTCTCTTT ACCGACAATA TACAAGTTTA 
CTTGGGAAAA TGAATTCAGA GGAGGAAGAT GAAGTGTGGC AGGTGATCAT AGGAGCCAGA 
GCTGAGATGA CTTCAAAACA CCAAGAGTAC TTGAAGCTGG AAACCACTTG GATGACTGCA 
GTTGGTCTTT CAGAGATGGC AGCAGAAGCT GCATATCAAA CTGGCGCAGA TCAGGCCTCT 
ATAACCGCCA GGAATCACAT TCAGCTGGTG AAACTGCAGG TGGAAGAGGT GCACCAGCTC 
TCCCGGAAAG CAGAAACCAA GCTGGCAGAA GCACAGATAG AAGAGCTCCG TCAGAAAACA 
CAGGAGGAAG GGGAGGAGCG GGCTGAGTCG GAGCAGGAGG CCTACCTGCG TGAGGATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_063940.1
CDS	741..1460
Translation	MAALKSWLSRSVTSFFRYRQCLCVPVVANFKKRCFSELIRPWHKTVTIGFGVTLCAVPIAQKSEPHSLSSEALMRRAVSLVTDSTSTFLSQTTYALIEAITEYTKAVYTLTSLYRQYTSLLGKMNSEEEDEVWQVIIGARAEMTSKHQEYLKLETTWMTAVGLSEMAAEAAYQTGADQASITARNHIQLVKLQVEEVHQLSRKAETKLAEAQIEELRQKTQEEGEERAESEQEAYLRED

Target ORF information:

RefSeq Version	NM_019887.6
Organism	Homo sapiens(human)
Definition	Homo sapiens diablo IAP-binding mitochondrial protein (DIABLO), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019887.6

ORF Insert Sequence:

ATGGCGGCTC TGAAGAGTTG GCTGTCGCGC AGCGTAACTT CATTCTTCAG GTACAGACAG 
TGTTTGTGTG TTCCTGTTGT GGCTAACTTT AAGAAGCGGT GTTTCTCAGA ATTGATAAGA 
CCATGGCACA AAACTGTGAC GATTGGCTTT GGAGTAACCC TGTGTGCGGT TCCTATTGCA 
CAGAAATCAG AGCCTCATTC CCTTAGTAGT GAAGCATTGA TGAGGAGAGC AGTGTCTTTG 
GTAACAGATA GCACCTCTAC CTTTCTCTCT CAGACCACAT ATGCGTTGAT TGAAGCTATT 
ACTGAATATA CTAAGGCTGT TTATACCTTA ACTTCTCTTT ACCGACAATA TACAAGTTTA 
CTTGGGAAAA TGAATTCAGA GGAGGAAGAT GAAGTGTGGC AGGTGATCAT AGGAGCCAGA 
GCTGAGATGA CTTCAAAACA CCAAGAGTAC TTGAAGCTGG AAACCACTTG GATGACTGCA 
GTTGGTCTTT CAGAGATGGC AGCAGAAGCT GCATATCAAA CTGGCGCAGA TCAGGCCTCT 
ATAACCGCCA GGAATCACAT TCAGCTGGTG AAACTGCAGG TGGAAGAGGT GCACCAGCTC 
TCCCGGAAAG CAGAAACCAA GCTGGCAGAA GCACAGATAG AAGAGCTCCG TCAGAAAACA 
CAGGAGGAAG GGGAGGAGCG GGCTGAGTCG GAGCAGGAGG CCTACCTGCG TGAGGATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DIABLO ( NM_001371333.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001358262.1 Homo sapiens diablo IAP-binding mitochondrial protein (DIABLO), transcript variant 8, mRNA.

Price & Availability↑

CloneID	OHu27599
Clone ID Related Accession (Same CDS sequence)	NM_019887.5 , NM_019887.6 , NM_001371333.1
Accession Version	NM_001371333.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 720bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-19
Organism	Homo sapiens(human)
Product	diablo homolog, mitochondrial isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC048338.29 and AF262240.1. This sequence is a reference standard in the RefSeqGene project. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.481583.1, SRR1660805.394582.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: PMID: 10929711; reported by MitoCarta MANE Ensembl match :: ENST00000464942.7/ ENSP00000442360.2 RefSeq Select criteria :: based on manual assertion, conservation, expression, longest protein ##RefSeq-Attributes-END##

ATGGCGGCTC TGAAGAGTTG GCTGTCGCGC AGCGTAACTT CATTCTTCAG GTACAGACAG 
TGTTTGTGTG TTCCTGTTGT GGCTAACTTT AAGAAGCGGT GTTTCTCAGA ATTGATAAGA 
CCATGGCACA AAACTGTGAC GATTGGCTTT GGAGTAACCC TGTGTGCGGT TCCTATTGCA 
CAGAAATCAG AGCCTCATTC CCTTAGTAGT GAAGCATTGA TGAGGAGAGC AGTGTCTTTG 
GTAACAGATA GCACCTCTAC CTTTCTCTCT CAGACCACAT ATGCGTTGAT TGAAGCTATT 
ACTGAATATA CTAAGGCTGT TTATACCTTA ACTTCTCTTT ACCGACAATA TACAAGTTTA 
CTTGGGAAAA TGAATTCAGA GGAGGAAGAT GAAGTGTGGC AGGTGATCAT AGGAGCCAGA 
GCTGAGATGA CTTCAAAACA CCAAGAGTAC TTGAAGCTGG AAACCACTTG GATGACTGCA 
GTTGGTCTTT CAGAGATGGC AGCAGAAGCT GCATATCAAA CTGGCGCAGA TCAGGCCTCT 
ATAACCGCCA GGAATCACAT TCAGCTGGTG AAACTGCAGG TGGAAGAGGT GCACCAGCTC 
TCCCGGAAAG CAGAAACCAA GCTGGCAGAA GCACAGATAG AAGAGCTCCG TCAGAAAACA 
CAGGAGGAAG GGGAGGAGCG GGCTGAGTCG GAGCAGGAGG CCTACCTGCG TGAGGATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001358262.1
CDS	39..758
Translation	MAALKSWLSRSVTSFFRYRQCLCVPVVANFKKRCFSELIRPWHKTVTIGFGVTLCAVPIAQKSEPHSLSSEALMRRAVSLVTDSTSTFLSQTTYALIEAITEYTKAVYTLTSLYRQYTSLLGKMNSEEEDEVWQVIIGARAEMTSKHQEYLKLETTWMTAVGLSEMAAEAAYQTGADQASITARNHIQLVKLQVEEVHQLSRKAETKLAEAQIEELRQKTQEEGEERAESEQEAYLRED

Target ORF information:

RefSeq Version	NM_001371333.1
Organism	Homo sapiens(human)
Definition	Homo sapiens diablo IAP-binding mitochondrial protein (DIABLO), transcript variant 8, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001371333.1

ORF Insert Sequence:

ATGGCGGCTC TGAAGAGTTG GCTGTCGCGC AGCGTAACTT CATTCTTCAG GTACAGACAG 
TGTTTGTGTG TTCCTGTTGT GGCTAACTTT AAGAAGCGGT GTTTCTCAGA ATTGATAAGA 
CCATGGCACA AAACTGTGAC GATTGGCTTT GGAGTAACCC TGTGTGCGGT TCCTATTGCA 
CAGAAATCAG AGCCTCATTC CCTTAGTAGT GAAGCATTGA TGAGGAGAGC AGTGTCTTTG 
GTAACAGATA GCACCTCTAC CTTTCTCTCT CAGACCACAT ATGCGTTGAT TGAAGCTATT 
ACTGAATATA CTAAGGCTGT TTATACCTTA ACTTCTCTTT ACCGACAATA TACAAGTTTA 
CTTGGGAAAA TGAATTCAGA GGAGGAAGAT GAAGTGTGGC AGGTGATCAT AGGAGCCAGA 
GCTGAGATGA CTTCAAAACA CCAAGAGTAC TTGAAGCTGG AAACCACTTG GATGACTGCA 
GTTGGTCTTT CAGAGATGGC AGCAGAAGCT GCATATCAAA CTGGCGCAGA TCAGGCCTCT 
ATAACCGCCA GGAATCACAT TCAGCTGGTG AAACTGCAGG TGGAAGAGGT GCACCAGCTC 
TCCCGGAAAG CAGAAACCAA GCTGGCAGAA GCACAGATAG AAGAGCTCCG TCAGAAAACA 
CAGGAGGAAG GGGAGGAGCG GGCTGAGTCG GAGCAGGAGG CCTACCTGCG TGAGGATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DIABLO ( NM_001278304.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001265233.1 Homo sapiens diablo IAP-binding mitochondrial protein (DIABLO), transcript variant 7, mRNA.

Price & Availability↑

CloneID	OHu14896
Clone ID Related Accession (Same CDS sequence)	NM_001278304.1 , NM_001278304.2 , NM_138930.3
Accession Version	NM_001278304.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 561bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Homo sapiens(human)
Product	diablo homolog, mitochondrial isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK001399.1, DB254800.1, AK057778.1 and N66735.1. Transcript Variant: This variant (7) differs in its 5' UTR and 5' coding region, and uses an alternate start codon, compared to variant 1. The encoded isoform (2, also known as Smac-beta and Smac/DIABLO-S) has a shorter and distinct N-terminus, compared to isoform 1. Isoform 2 has a cortical, instead of a mitochondrial, subcellular distribution, and lacks the inhibitor of apoptosis protein-binding domain but maintains the ability to potentiate apoptosis (PMID: 11285287). Variants 2 and 7 encode the same isoform. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK001399.1, SRR1660805.5437.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: PMID: 10929711; reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAAATCTG ACTTCTACTT CCAGAAATCA GAGCCTCATT CCCTTAGTAG TGAAGCATTG 
ATGAGGAGAG CAGTGTCTTT GGTAACAGAT AGCACCTCTA CCTTTCTCTC TCAGACCACA 
TATGCGTTGA TTGAAGCTAT TACTGAATAT ACTAAGGCTG TTTATACCTT AACTTCTCTT 
TACCGACAAT ATACAAGTTT ACTTGGGAAA ATGAATTCAG AGGAGGAAGA TGAAGTGTGG 
CAGGTGATCA TAGGAGCCAG AGCTGAGATG ACTTCAAAAC ACCAAGAGTA CTTGAAGCTG 
GAAACCACTT GGATGACTGC AGTTGGTCTT TCAGAGATGG CAGCAGAAGC TGCATATCAA 
ACTGGCGCAG ATCAGGCCTC TATAACCGCC AGGAATCACA TTCAGCTGGT GAAACTGCAG 
GTGGAAGAGG TGCACCAGCT CTCCCGGAAA GCAGAAACCA AGCTGGCAGA AGCACAGATA 
GAAGAGCTCC GTCAGAAAAC ACAGGAGGAA GGGGAGGAGC GGGCTGAGTC GGAGCAGGAG 
GCCTACCTGC GTGAGGATTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001265233.1
CDS	1183..1743
Translation	MKSDFYFQKSEPHSLSSEALMRRAVSLVTDSTSTFLSQTTYALIEAITEYTKAVYTLTSLYRQYTSLLGKMNSEEEDEVWQVIIGARAEMTSKHQEYLKLETTWMTAVGLSEMAAEAAYQTGADQASITARNHIQLVKLQVEEVHQLSRKAETKLAEAQIEELRQKTQEEGEERAESEQEAYLRED

Target ORF information:

RefSeq Version	NM_001278304.1
Organism	Homo sapiens(human)
Definition	Homo sapiens diablo IAP-binding mitochondrial protein (DIABLO), transcript variant 7, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001278304.1

ORF Insert Sequence:

ATGAAATCTG ACTTCTACTT CCAGAAATCA GAGCCTCATT CCCTTAGTAG TGAAGCATTG 
ATGAGGAGAG CAGTGTCTTT GGTAACAGAT AGCACCTCTA CCTTTCTCTC TCAGACCACA 
TATGCGTTGA TTGAAGCTAT TACTGAATAT ACTAAGGCTG TTTATACCTT AACTTCTCTT 
TACCGACAAT ATACAAGTTT ACTTGGGAAA ATGAATTCAG AGGAGGAAGA TGAAGTGTGG 
CAGGTGATCA TAGGAGCCAG AGCTGAGATG ACTTCAAAAC ACCAAGAGTA CTTGAAGCTG 
GAAACCACTT GGATGACTGC AGTTGGTCTT TCAGAGATGG CAGCAGAAGC TGCATATCAA 
ACTGGCGCAG ATCAGGCCTC TATAACCGCC AGGAATCACA TTCAGCTGGT GAAACTGCAG 
GTGGAAGAGG TGCACCAGCT CTCCCGGAAA GCAGAAACCA AGCTGGCAGA AGCACAGATA 
GAAGAGCTCC GTCAGAAAAC ACAGGAGGAA GGGGAGGAGC GGGCTGAGTC GGAGCAGGAG 
GCCTACCTGC GTGAGGATTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DIABLO ( NM_001278304.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001265233.1 Homo sapiens diablo IAP-binding mitochondrial protein (DIABLO), transcript variant 7, mRNA.

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CloneID	OHu14896
Clone ID Related Accession (Same CDS sequence)	NM_001278304.1 , NM_001278304.2 , NM_138930.3
Accession Version	NM_001278304.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 561bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-07
Organism	Homo sapiens(human)
Product	diablo homolog, mitochondrial isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK001399.1, DB254800.1, AK057778.1 and N66735.1. On Jun 2, 2019 this sequence version replaced NM_001278304.1. Transcript Variant: This variant (7) differs in its 5' UTR and 5' coding region, and uses an alternate start codon, compared to variant 1. The encoded isoform (2, also known as Smac-beta and Smac/DIABLO-S) has a shorter and distinct N-terminus, compared to isoform 1. Isoform 2 has a cortical, instead of a mitochondrial, subcellular distribution, and lacks the inhibitor of apoptosis protein-binding domain but maintains the ability to potentiate apoptosis (PMID: 11285287). Variants 2 and 7 encode the same isoform. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.1154911.1, SRR1803612.242849.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: PMID: 10929711; reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAAATCTG ACTTCTACTT CCAGAAATCA GAGCCTCATT CCCTTAGTAG TGAAGCATTG 
ATGAGGAGAG CAGTGTCTTT GGTAACAGAT AGCACCTCTA CCTTTCTCTC TCAGACCACA 
TATGCGTTGA TTGAAGCTAT TACTGAATAT ACTAAGGCTG TTTATACCTT AACTTCTCTT 
TACCGACAAT ATACAAGTTT ACTTGGGAAA ATGAATTCAG AGGAGGAAGA TGAAGTGTGG 
CAGGTGATCA TAGGAGCCAG AGCTGAGATG ACTTCAAAAC ACCAAGAGTA CTTGAAGCTG 
GAAACCACTT GGATGACTGC AGTTGGTCTT TCAGAGATGG CAGCAGAAGC TGCATATCAA 
ACTGGCGCAG ATCAGGCCTC TATAACCGCC AGGAATCACA TTCAGCTGGT GAAACTGCAG 
GTGGAAGAGG TGCACCAGCT CTCCCGGAAA GCAGAAACCA AGCTGGCAGA AGCACAGATA 
GAAGAGCTCC GTCAGAAAAC ACAGGAGGAA GGGGAGGAGC GGGCTGAGTC GGAGCAGGAG 
GCCTACCTGC GTGAGGATTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001265233.1
CDS	1104..1664
Translation	MKSDFYFQKSEPHSLSSEALMRRAVSLVTDSTSTFLSQTTYALIEAITEYTKAVYTLTSLYRQYTSLLGKMNSEEEDEVWQVIIGARAEMTSKHQEYLKLETTWMTAVGLSEMAAEAAYQTGADQASITARNHIQLVKLQVEEVHQLSRKAETKLAEAQIEELRQKTQEEGEERAESEQEAYLRED

Target ORF information:

RefSeq Version	NM_001278304.2
Organism	Homo sapiens(human)
Definition	Homo sapiens diablo IAP-binding mitochondrial protein (DIABLO), transcript variant 7, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001278304.2

ORF Insert Sequence:

ATGAAATCTG ACTTCTACTT CCAGAAATCA GAGCCTCATT CCCTTAGTAG TGAAGCATTG 
ATGAGGAGAG CAGTGTCTTT GGTAACAGAT AGCACCTCTA CCTTTCTCTC TCAGACCACA 
TATGCGTTGA TTGAAGCTAT TACTGAATAT ACTAAGGCTG TTTATACCTT AACTTCTCTT 
TACCGACAAT ATACAAGTTT ACTTGGGAAA ATGAATTCAG AGGAGGAAGA TGAAGTGTGG 
CAGGTGATCA TAGGAGCCAG AGCTGAGATG ACTTCAAAAC ACCAAGAGTA CTTGAAGCTG 
GAAACCACTT GGATGACTGC AGTTGGTCTT TCAGAGATGG CAGCAGAAGC TGCATATCAA 
ACTGGCGCAG ATCAGGCCTC TATAACCGCC AGGAATCACA TTCAGCTGGT GAAACTGCAG 
GTGGAAGAGG TGCACCAGCT CTCCCGGAAA GCAGAAACCA AGCTGGCAGA AGCACAGATA 
GAAGAGCTCC GTCAGAAAAC ACAGGAGGAA GGGGAGGAGC GGGCTGAGTC GGAGCAGGAG 
GCCTACCTGC GTGAGGATTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DIABLO ( NM_138930.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_620308.1 Homo sapiens diablo IAP-binding mitochondrial protein (DIABLO), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu14896
Clone ID Related Accession (Same CDS sequence)	NM_001278304.1 , NM_001278304.2 , NM_138930.3
Accession Version	NM_138930.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 561bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-07
Organism	Homo sapiens(human)
Product	diablo homolog, mitochondrial isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA877400.1, BC046209.1, BC095468.1, AK057778.1 and N66735.1. On or before May 31, 2013 this sequence version replaced NR_024600.1, NM_138930.2. Transcript Variant: This variant (2) differs in its 5' UTR and 5' coding region, and uses an alternate start codon, compared to variant 1. The encoded isoform (2, also known as Smac-beta and Smac/DIABLO-S) has a shorter and distinct N-terminus, compared to isoform 1. Isoform 2 has a cortical, instead of a mitochondrial, subcellular distribution, and lacks the inhibitor of apoptosis protein-binding domain but maintains the ability to potentiate apoptosis (PMID: 11285287). Variants 2 and 7 encode the same isoform. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC095468.1, SRR1660809.311907.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: PMID: 10929711; reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAAATCTG ACTTCTACTT CCAGAAATCA GAGCCTCATT CCCTTAGTAG TGAAGCATTG 
ATGAGGAGAG CAGTGTCTTT GGTAACAGAT AGCACCTCTA CCTTTCTCTC TCAGACCACA 
TATGCGTTGA TTGAAGCTAT TACTGAATAT ACTAAGGCTG TTTATACCTT AACTTCTCTT 
TACCGACAAT ATACAAGTTT ACTTGGGAAA ATGAATTCAG AGGAGGAAGA TGAAGTGTGG 
CAGGTGATCA TAGGAGCCAG AGCTGAGATG ACTTCAAAAC ACCAAGAGTA CTTGAAGCTG 
GAAACCACTT GGATGACTGC AGTTGGTCTT TCAGAGATGG CAGCAGAAGC TGCATATCAA 
ACTGGCGCAG ATCAGGCCTC TATAACCGCC AGGAATCACA TTCAGCTGGT GAAACTGCAG 
GTGGAAGAGG TGCACCAGCT CTCCCGGAAA GCAGAAACCA AGCTGGCAGA AGCACAGATA 
GAAGAGCTCC GTCAGAAAAC ACAGGAGGAA GGGGAGGAGC GGGCTGAGTC GGAGCAGGAG 
GCCTACCTGC GTGAGGATTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_620308.1
CDS	685..1245
Translation	MKSDFYFQKSEPHSLSSEALMRRAVSLVTDSTSTFLSQTTYALIEAITEYTKAVYTLTSLYRQYTSLLGKMNSEEEDEVWQVIIGARAEMTSKHQEYLKLETTWMTAVGLSEMAAEAAYQTGADQASITARNHIQLVKLQVEEVHQLSRKAETKLAEAQIEELRQKTQEEGEERAESEQEAYLRED

Target ORF information:

RefSeq Version	NM_138930.3
Organism	Homo sapiens(human)
Definition	Homo sapiens diablo IAP-binding mitochondrial protein (DIABLO), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_138930.3

ORF Insert Sequence:

ATGAAATCTG ACTTCTACTT CCAGAAATCA GAGCCTCATT CCCTTAGTAG TGAAGCATTG 
ATGAGGAGAG CAGTGTCTTT GGTAACAGAT AGCACCTCTA CCTTTCTCTC TCAGACCACA 
TATGCGTTGA TTGAAGCTAT TACTGAATAT ACTAAGGCTG TTTATACCTT AACTTCTCTT 
TACCGACAAT ATACAAGTTT ACTTGGGAAA ATGAATTCAG AGGAGGAAGA TGAAGTGTGG 
CAGGTGATCA TAGGAGCCAG AGCTGAGATG ACTTCAAAAC ACCAAGAGTA CTTGAAGCTG 
GAAACCACTT GGATGACTGC AGTTGGTCTT TCAGAGATGG CAGCAGAAGC TGCATATCAA 
ACTGGCGCAG ATCAGGCCTC TATAACCGCC AGGAATCACA TTCAGCTGGT GAAACTGCAG 
GTGGAAGAGG TGCACCAGCT CTCCCGGAAA GCAGAAACCA AGCTGGCAGA AGCACAGATA 
GAAGAGCTCC GTCAGAAAAC ACAGGAGGAA GGGGAGGAGC GGGCTGAGTC GGAGCAGGAG 
GCCTACCTGC GTGAGGATTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DIABLO ( NM_001278302.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001265231.1 Homo sapiens diablo IAP-binding mitochondrial protein (DIABLO), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu27633
Clone ID Related Accession (Same CDS sequence)	NM_001278302.1
Accession Version	NM_001278302.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 429bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-07
Organism	Homo sapiens(human)
Product	diablo homolog, mitochondrial isoform 4
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA877400.1, BC046209.1, BC095468.1, JX679472.1, AK057778.1 and N66735.1. On May 31, 2013 this sequence version replaced NR_024601.1. Transcript Variant: This variant (5) differs in its 5' UTR and 5' coding region, uses an alternate start codon, and lacks an in-frame exon in the internal coding region, compared to variant 1. The encoded isoform (4) has a distinct N-terminus and is shorter, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BM739108.1, BM746689.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2155751, SAMEA2161674 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: PMID: 10929711; reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAAATCTG ACTTCTACTT CCAGGCTGTT TATACCTTAA CTTCTCTTTA CCGACAATAT 
ACAAGTTTAC TTGGGAAAAT GAATTCAGAG GAGGAAGATG AAGTGTGGCA GGTGATCATA 
GGAGCCAGAG CTGAGATGAC TTCAAAACAC CAAGAGTACT TGAAGCTGGA AACCACTTGG 
ATGACTGCAG TTGGTCTTTC AGAGATGGCA GCAGAAGCTG CATATCAAAC TGGCGCAGAT 
CAGGCCTCTA TAACCGCCAG GAATCACATT CAGCTGGTGA AACTGCAGGT GGAAGAGGTG 
CACCAGCTCT CCCGGAAAGC AGAAACCAAG CTGGCAGAAG CACAGATAGA AGAGCTCCGT 
CAGAAAACAC AGGAGGAAGG GGAGGAGCGG GCTGAGTCGG AGCAGGAGGC CTACCTGCGT 
GAGGATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001265231.1
CDS	685..1113
Translation	MKSDFYFQAVYTLTSLYRQYTSLLGKMNSEEEDEVWQVIIGARAEMTSKHQEYLKLETTWMTAVGLSEMAAEAAYQTGADQASITARNHIQLVKLQVEEVHQLSRKAETKLAEAQIEELRQKTQEEGEERAESEQEAYLRED

Target ORF information:

RefSeq Version	NM_001278302.1
Organism	Homo sapiens(human)
Definition	Homo sapiens diablo IAP-binding mitochondrial protein (DIABLO), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001278302.1

ORF Insert Sequence:

ATGAAATCTG ACTTCTACTT CCAGGCTGTT TATACCTTAA CTTCTCTTTA CCGACAATAT 
ACAAGTTTAC TTGGGAAAAT GAATTCAGAG GAGGAAGATG AAGTGTGGCA GGTGATCATA 
GGAGCCAGAG CTGAGATGAC TTCAAAACAC CAAGAGTACT TGAAGCTGGA AACCACTTGG 
ATGACTGCAG TTGGTCTTTC AGAGATGGCA GCAGAAGCTG CATATCAAAC TGGCGCAGAT 
CAGGCCTCTA TAACCGCCAG GAATCACATT CAGCTGGTGA AACTGCAGGT GGAAGAGGTG 
CACCAGCTCT CCCGGAAAGC AGAAACCAAG CTGGCAGAAG CACAGATAGA AGAGCTCCGT 
CAGAAAACAC AGGAGGAAGG GGAGGAGCGG GCTGAGTCGG AGCAGGAGGC CTACCTGCGT 
GAGGATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DIABLO ( NM_001278342.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001265271.1 Homo sapiens diablo IAP-binding mitochondrial protein (DIABLO), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu27641
Clone ID Related Accession (Same CDS sequence)	NM_001278342.1
Accession Version	NM_001278342.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 588bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-07
Organism	Homo sapiens(human)
Product	diablo homolog, mitochondrial isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA877400.1, BC046209.1, AY313210.1, AK057778.1 and N66735.1. Transcript Variant: This variant (3) has a shorter 5' UTR, and lacks an alternate in-frame exon in the coding region, compared to variant 1. The encoded isoform (3, also known as Smac-delta and Smac3) is shorter, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK057778.1, SRR1163655.596755.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA2152798 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: downstream AUG is associated with N-terminal localization signal (PMID:14523016) gene product(s) localized to mito. :: PMID: 10929711; reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCTC TGAAGAGTTG GCTGTCGCGC AGCGTAACTT CATTCTTCAG GTACAGACAG 
TGTTTGTGTG TTCCTGTTGT GGCTAACTTT AAGAAGCGGT GTTTCTCAGA ATTGATAAGA 
CCATGGCACA AAACTGTGAC GATTGGCTTT GGAGTAACCC TGTGTGCGGT TCCTATTGCA 
CAGGCTGTTT ATACCTTAAC TTCTCTTTAC CGACAATATA CAAGTTTACT TGGGAAAATG 
AATTCAGAGG AGGAAGATGA AGTGTGGCAG GTGATCATAG GAGCCAGAGC TGAGATGACT 
TCAAAACACC AAGAGTACTT GAAGCTGGAA ACCACTTGGA TGACTGCAGT TGGTCTTTCA 
GAGATGGCAG CAGAAGCTGC ATATCAAACT GGCGCAGATC AGGCCTCTAT AACCGCCAGG 
AATCACATTC AGCTGGTGAA ACTGCAGGTG GAAGAGGTGC ACCAGCTCTC CCGGAAAGCA 
GAAACCAAGC TGGCAGAAGC ACAGATAGAA GAGCTCCGTC AGAAAACACA GGAGGAAGGG 
GAGGAGCGGG CTGAGTCGGA GCAGGAGGCC TACCTGCGTG AGGATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001265271.1
CDS	555..1142
Translation	MAALKSWLSRSVTSFFRYRQCLCVPVVANFKKRCFSELIRPWHKTVTIGFGVTLCAVPIAQAVYTLTSLYRQYTSLLGKMNSEEEDEVWQVIIGARAEMTSKHQEYLKLETTWMTAVGLSEMAAEAAYQTGADQASITARNHIQLVKLQVEEVHQLSRKAETKLAEAQIEELRQKTQEEGEERAESEQEAYLRED

Target ORF information:

RefSeq Version	NM_001278342.1
Organism	Homo sapiens(human)
Definition	Homo sapiens diablo IAP-binding mitochondrial protein (DIABLO), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001278342.1

ORF Insert Sequence:

ATGGCGGCTC TGAAGAGTTG GCTGTCGCGC AGCGTAACTT CATTCTTCAG GTACAGACAG 
TGTTTGTGTG TTCCTGTTGT GGCTAACTTT AAGAAGCGGT GTTTCTCAGA ATTGATAAGA 
CCATGGCACA AAACTGTGAC GATTGGCTTT GGAGTAACCC TGTGTGCGGT TCCTATTGCA 
CAGGCTGTTT ATACCTTAAC TTCTCTTTAC CGACAATATA CAAGTTTACT TGGGAAAATG 
AATTCAGAGG AGGAAGATGA AGTGTGGCAG GTGATCATAG GAGCCAGAGC TGAGATGACT 
TCAAAACACC AAGAGTACTT GAAGCTGGAA ACCACTTGGA TGACTGCAGT TGGTCTTTCA 
GAGATGGCAG CAGAAGCTGC ATATCAAACT GGCGCAGATC AGGCCTCTAT AACCGCCAGG 
AATCACATTC AGCTGGTGAA ACTGCAGGTG GAAGAGGTGC ACCAGCTCTC CCGGAAAGCA 
GAAACCAAGC TGGCAGAAGC ACAGATAGAA GAGCTCCGTC AGAAAACACA GGAGGAAGGG 
GAGGAGCGGG CTGAGTCGGA GCAGGAGGCC TACCTGCGTG AGGATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Gene Symbol	DIABLO
Entrez Gene ID	56616
Full Name	diablo IAP-binding mitochondrial protein
Synonyms	DFNA64,SMAC
General protein information	Preferred Names diablo IAP-binding mitochondrial protein Names diablo homolog, mitochondrial diablo-like protein direct IAP-binding protein with low pI second mitochondria-derived activator of caspase
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 12 Map Location: 12q24.31
Summary	This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013].
Disorder MIM:	605219
Disorder Html:	Deafness, autosomal dominant 64, 614152 (3)

Xenopus tropicalis (tropical clawed frog)	diablo	NP_001016281.1
Pan troglodytes (chimpanzee)	DIABLO	XP_001150587.2
Canis lupus familiaris (dog)	DIABLO	NP_001073235.1
Bos taurus (cattle)	DIABLO	NP_001039347.1
Mus musculus (house mouse)	Diablo	NP_075721.3
Gallus gallus (chicken)	DIABLO	XP_415152.3
Homo sapiens (human)	DIABLO	NP_063940.1

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

DIABLO cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

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