SUSD2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SUSD2
Entrez Gene ID	56241
Full Name	sushi domain containing 2
Synonyms	BK65A6.2
General protein information	Preferred Names sushi domain containing 2 Names sushi domain-containing protein 2 Sushi domain (SCR repeat) containing testicular tissue protein Li 190
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 22 Map Location: 22q11.23
Disorder MIM:	615825

mRNA and Protein(s)

mRNA	Protein	Name
NM_019601.4	NP_062547.1	sushi domain-containing protein 2 precursor
NM_019601.3	NP_062547.1	sushi domain-containing protein 2 precursor

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	SUSD2	XP_543528.4
Caenorhabditis elegans (roundworm)	CELE_K03H1.5	NP_499205.1
Pan troglodytes (chimpanzee)	SUSD2	XP_515031.4
Danio rerio (zebrafish)	LOC793335	XP_001333073.5
Homo sapiens (human)	SUSD2	NP_062547.1
Mus musculus (house mouse)	Susd2	NP_082166.3
Rattus norvegicus (Norway rat)	Susd2	NP_001099851.1
Gallus gallus (chicken)	SUSD2	XP_415212.4
Drosophila melanogaster (fruit fly)	CG31004	NP_001163782.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP000550	XP_310533.5
Bos taurus (cattle)	SUSD2	NP_001192604.1

Gene Ontology
Bibliography

Related articles in PubMed

SUSD2 promotes tumor-associated macrophage recruitment by increasing levels of MCP-1 in breast cancer.
Hultgren EM, Patrick ME, Evans RL, Stoos CT, Egland KA
PloS one12(5)e0177089(2017)

Downregulation of endometrial mesenchymal marker SUSD2 causes cell senescence and cell death in endometrial carcinoma cells.
Zhang S, Zeng N, Alowayed N, Singh Y, Cheng A, Lang F, Salker MS
PloS one12(8)e0183681(2017)

SUSD2 is frequently downregulated and functions as a tumor suppressor in RCC and lung cancer.
Cheng Y, Wang X, Wang P, Li T, Hu F, Liu Q, Yang F, Wang J, Xu T, Han W
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine37(7)9919-30(2016 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Tumors with high levels of SUSD2 staining contained 2-fold more tumor-associated macrophages, mainly of the M2 pro-angiogenic phenotype
Title: SUSD2 promotes tumor-associated macrophage recruitment by increasing levels of MCP-1 in breast cancer.

suggest that SUSD2 counteracts senescence and cell death and is thus a potential chemotherapeutic target in human endometrial cancer
Title: Downregulation of endometrial mesenchymal marker SUSD2 causes cell senescence and cell death in endometrial carcinoma cells.

Low SUSD2 expression is associated with renal cell carcinoma and lung cancer.
Title: SUSD2 is frequently downregulated and functions as a tumor suppressor in RCC and lung cancer.

No evidence of association between polymorphisms in SUSD2 and sporadic amyotrophic lateral sclerosis in Han Chinese
Title: No evidence of association between polymorphisms in four genes and sporadic amyotrophic lateral sclerosis in Han Chinese.

Two new susceptibility loci for amyotrophic lateral sclerosis in the Han Chinese population in chromosome 1, CAMK1G and chromosome 22, SUSD2 and CABIN1.
Title: Genome-wide association analyses in Han Chinese identify two new susceptibility loci for amyotrophic lateral sclerosis.

The following SUSD2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SUSD2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu27875	NM_019601.4 Latest version!	Homo sapiens sushi domain containing 2 (SUSD2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
View Old Accession Versions >>
OHu27875	NM_019601.3	Homo sapiens sushi domain containing 2 (SUSD2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SUSD2 ( NM_019601.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_062547.1 Homo sapiens sushi domain containing 2 (SUSD2), mRNA.

Price & Availability↑

CloneID	OHu27875
Clone ID Related Accession (Same CDS sequence)	NM_019601.4 , NM_019601.3
Accession Version	NM_019601.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2469bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	sushi domain-containing protein 2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC033107.1 and BI822588.1. On Nov 23, 2018 this sequence version replaced NM_019601.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC033107.1, SRR1803615.96957.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000358321.4/ ENSP00000351075.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAAGCCAG CCCTCCTGCC CTGGGCCCTG CTGCTGCTGG CGACAGCCCT CGGCCCGGGC 
CCCGGACCCA CAGCAGATGC CCAAGAGAGC TGCTCCATGC GCTGTGGCGC CCTGGACGGG 
CCATGTTCCT GCCACCCGAC GTGCTCTGGC CTTGGCACCT GCTGCTTGGA TTTCCGGGAC 
TTCTGCCTGG AGATATTGCC CTACTCAGGA TCCATGATGG GCGGCAAGGA CTTTGTGGTG 
CGGCACTTCA AGATGTCCAG CCCCACAGAC GCCAGTGTGA TCTGCAGGTT TAAGGACAGC 
ATCCAGACCC TCGGCCATGT GGACTCCTCC GGGCAAGTGC ACTGTGTGTC ACCTCTGCTC 
TATGAGAGCG GCCGCATCCC CTTCACTGTG TCACTGGACA ACGGCCACTC CTTCCCTCGT 
GCGGGCACCT GGCTGGCTGT GCACCCCAAC AAAGTGTCAA TGATGGAGAA GAGCGAGTTG 
GTGAACGAGA CGCGTTGGCA ATACTACGGC ACCGCCAACA CCTCAGGCAA CCTCAGCCTG 
ACCTGGCATG TCAAGTCGCT GCCCACGCAG ACCATCACCA TCGAACTGTG GGGCTACGAG 
GAGACAGGAA TGCCCTACTC ACAGGAGTGG ACTGCAAAGT GGTCGTACCT GTACCCCCTG 
GCCACACACA TCCCCAACTC CGGCTCTTTC ACTTTCACCC CAAAACCTGC TCCTCCCAGC 
TACCAGAGAT GGCGAGTGGG TGCACTTCGG ATCATCGACA GCAAAAATTA CGCAGGGCAG 
AAGGACGTGC AGGCGCTCTG GACCAACGAC CACGCACTGG CCTGGCACCT GAGCGATGAC 
TTCCGAGAGG ACCCTGTGGC CTGGGCACGA ACTCAGTGCC AGGCCTGGGA GGAGCTGGAG 
GATCAGCTGC CCAACTTCCT GGAGGAGCTG CCGGACTGCC CCTGCACCCT GACCCAGGCC 
CGGGCTGACT CCGGCCGCTT CTTCACGGAC TACGGCTGTG ACATGGAGCA GGGCAGCGTG 
TGCACCTACC ACCCCGGGGC CGTGCACTGT GTGCGTTCTG TGCAGGCCAG CCTCCGGTAC 
GGCTCAGGTC AGCAGTGCTG CTACACAGCG GACGGGACGC AGCTCCTGAC AGCTGACTCC 
AGCGGCGGCA GCACTCCCGA CCGCGGCCAT GACTGGGGCG CACCCCCGTT CCGCACGCCA 
CCCCGAGTGC CCAGCATGTC CCACTGGCTC TACGATGTCC TCAGCTTCTA TTACTGCTGC 
CTCTGGGCAC CCGACTGCCC CCGCTACATG CAACGGCGGC CCTCCAATGA CTGCCGCAAC 
TACCGGCCCC CAAGACTGGC CTCCGCCTTC GGAGACCCAC ACTTTGTGAC CTTCGACGGC 
ACCAACTTCA CATTCAATGG GCGCGGAGAG TACGTGCTGC TGGAGGCAGC GCTGACCGAC 
CTGAGGGTGC AGGCGCGGGC CCAGCCCGGG ACGATGTCCA ACGGCACGGA GACCCGTGGC 
ACTGGGCTGA CCGCAGTGGC CGTCCAGGAG GGCAACTCAG ATGTGGTGGA AGTCAGGCTG 
GCCAACAGGA CCGGAGGTCT GGAGGTGCTG CTGAACCAGG AGGTGCTGAG CTTCACCGAG 
CAGAGCTGGA TGGACCTGAA AGGAATGTTC CTGTCGGTGG CTGCCGGGGA CAGGGTCTCC 
ATCATGCTGG CATCAGGGGC CGGCCTGGAG GTCAGCGTGC AGGGCCCGTT CCTGAGTGTG 
TCCGTCCTGC TGCCTGAGAA GTTCCTCACC CACACCCACG GCCTCCTCGG GACACTCAAC 
AACGACCCCA CCGACGACTT CACCCTGCAC AGCGGGCGCG TCCTGCCCCC AGGCACCAGT 
CCCCAGGAGC TGTTCCTGTT TGGGGCCAAC TGGACCGTGC ACAATGCGTC CTCCCTGCTC 
ACCTACGATT CCTGGTTCCT GGTCCACAAC TTCCTGTACC AACCCAAGCA CGACCCCACC 
TTCGAGCCCC TCTTCCCCAG TGAGACCACC CTCAACCCCA GCCTGGCACA AGAGGCAGCC 
AAACTATGTG GGGACGATCA TTTCTGCAAC TTTGATGTGG CAGCCACTGG GAGCCTGAGC 
ACGGGCACTG CCACTCGGGT GGCCCACCAG CTGCACCAGC GTCGCATGCA GAGCCTGCAG 
CCAGTGGTGT CCTGTGGCTG GCTGGCCCCA CCTCCCAACG GACAAAAGGA GGGCAACAGG 
TACCTGGCGG GTTCCACCAT CTACTTCCAC TGTGACAACG GCTACAGCCT GGCCGGGGCA 
GAGACCAGCA CCTGCCAGGC TGACGGCACC TGGTCCTCAC CCACCCCGAA GTGCCAGCCA 
GGACGCAGCT ACGCGGTGCT GTTGGGCATC ATCTTTGGGG GCCTCGCGGT GGTGGCGGCG 
GTTGCGCTCG TCTATGTGCT GCTGCGCCGC AGGAAGGGCA ACACGCACGT CTGGGGTGCA 
CAGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_062547.1
CDS	34..2502
Translation	MKPALLPWALLLLATALGPGPGPTADAQESCSMRCGALDGPCSCHPTCSGLGTCCLDFRDFCLEILPYSGSMMGGKDFVVRHFKMSSPTDASVICRFKDSIQTLGHVDSSGQVHCVSPLLYESGRIPFTVSLDNGHSFPRAGTWLAVHPNKVSMMEKSELVNETRWQYYGTANTSGNLSLTWHVKSLPTQTITIELWGYEETGMPYSQEWTAKWSYLYPLATHIPNSGSFTFTPKPAPPSYQRWRVGALRIIDSKNYAGQKDVQALWTNDHALAWHLSDDFREDPVAWARTQCQAWEELEDQLPNFLEELPDCPCTLTQARADSGRFFTDYGCDMEQGSVCTYHPGAVHCVRSVQASLRYGSGQQCCYTADGTQLLTADSSGGSTPDRGHDWGAPPFRTPPRVPSMSHWLYDVLSFYYCCLWAPDCPRYMQRRPSNDCRNYRPPRLASAFGDPHFVTFDGTNFTFNGRGEYVLLEAALTDLRVQARAQPGTMSNGTETRGTGLTAVAVQEGNSDVVEVRLANRTGGLEVLLNQEVLSFTEQSWMDLKGMFLSVAAGDRVSIMLASGAGLEVSVQGPFLSVSVLLPEKFLTHTHGLLGTLNNDPTDDFTLHSGRVLPPGTSPQELFLFGANWTVHNASSLLTYDSWFLVHNFLYQPKHDPTFEPLFPSETTLNPSLAQEAAKLCGDDHFCNFDVAATGSLSTGTATRVAHQLHQRRMQSLQPVVSCGWLAPPPNGQKEGNRYLAGSTIYFHCDNGYSLAGAETSTCQADGTWSSPTPKCQPGRSYAVLLGIIFGGLAVVAAVALVYVLLRRRKGNTHVWGAQP

Target ORF information:

RefSeq Version	NM_019601.4
Organism	Homo sapiens(human)
Definition	Homo sapiens sushi domain containing 2 (SUSD2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019601.4

ORF Insert Sequence:

ATGAAGCCAG CCCTCCTGCC CTGGGCCCTG CTGCTGCTGG CGACAGCCCT CGGCCCGGGC 
CCCGGACCCA CAGCAGATGC CCAAGAGAGC TGCTCCATGC GCTGTGGCGC CCTGGACGGG 
CCATGTTCCT GCCACCCGAC GTGCTCTGGC CTTGGCACCT GCTGCTTGGA TTTCCGGGAC 
TTCTGCCTGG AGATATTGCC CTACTCAGGA TCCATGATGG GCGGCAAGGA CTTTGTGGTG 
CGGCACTTCA AGATGTCCAG CCCCACAGAC GCCAGTGTGA TCTGCAGGTT TAAGGACAGC 
ATCCAGACCC TCGGCCATGT GGACTCCTCC GGGCAAGTGC ACTGTGTGTC ACCTCTGCTC 
TATGAGAGCG GCCGCATCCC CTTCACTGTG TCACTGGACA ACGGCCACTC CTTCCCTCGT 
GCGGGCACCT GGCTGGCTGT GCACCCCAAC AAAGTGTCAA TGATGGAGAA GAGCGAGTTG 
GTGAACGAGA CGCGTTGGCA ATACTACGGC ACCGCCAACA CCTCAGGCAA CCTCAGCCTG 
ACCTGGCATG TCAAGTCGCT GCCCACGCAG ACCATCACCA TCGAACTGTG GGGCTACGAG 
GAGACAGGAA TGCCCTACTC ACAGGAGTGG ACTGCAAAGT GGTCGTACCT GTACCCCCTG 
GCCACACACA TCCCCAACTC CGGCTCTTTC ACTTTCACCC CAAAACCTGC TCCTCCCAGC 
TACCAGAGAT GGCGAGTGGG TGCACTTCGG ATCATCGACA GCAAAAATTA CGCAGGGCAG 
AAGGACGTGC AGGCGCTCTG GACCAACGAC CACGCACTGG CCTGGCACCT GAGCGATGAC 
TTCCGAGAGG ACCCTGTGGC CTGGGCACGA ACTCAGTGCC AGGCCTGGGA GGAGCTGGAG 
GATCAGCTGC CCAACTTCCT GGAGGAGCTG CCGGACTGCC CCTGCACCCT GACCCAGGCC 
CGGGCTGACT CCGGCCGCTT CTTCACGGAC TACGGCTGTG ACATGGAGCA GGGCAGCGTG 
TGCACCTACC ACCCCGGGGC CGTGCACTGT GTGCGTTCTG TGCAGGCCAG CCTCCGGTAC 
GGCTCAGGTC AGCAGTGCTG CTACACAGCG GACGGGACGC AGCTCCTGAC AGCTGACTCC 
AGCGGCGGCA GCACTCCCGA CCGCGGCCAT GACTGGGGCG CACCCCCGTT CCGCACGCCA 
CCCCGAGTGC CCAGCATGTC CCACTGGCTC TACGATGTCC TCAGCTTCTA TTACTGCTGC 
CTCTGGGCAC CCGACTGCCC CCGCTACATG CAACGGCGGC CCTCCAATGA CTGCCGCAAC 
TACCGGCCCC CAAGACTGGC CTCCGCCTTC GGAGACCCAC ACTTTGTGAC CTTCGACGGC 
ACCAACTTCA CATTCAATGG GCGCGGAGAG TACGTGCTGC TGGAGGCAGC GCTGACCGAC 
CTGAGGGTGC AGGCGCGGGC CCAGCCCGGG ACGATGTCCA ACGGCACGGA GACCCGTGGC 
ACTGGGCTGA CCGCAGTGGC CGTCCAGGAG GGCAACTCAG ATGTGGTGGA AGTCAGGCTG 
GCCAACAGGA CCGGAGGTCT GGAGGTGCTG CTGAACCAGG AGGTGCTGAG CTTCACCGAG 
CAGAGCTGGA TGGACCTGAA AGGAATGTTC CTGTCGGTGG CTGCCGGGGA CAGGGTCTCC 
ATCATGCTGG CATCAGGGGC CGGCCTGGAG GTCAGCGTGC AGGGCCCGTT CCTGAGTGTG 
TCCGTCCTGC TGCCTGAGAA GTTCCTCACC CACACCCACG GCCTCCTCGG GACACTCAAC 
AACGACCCCA CCGACGACTT CACCCTGCAC AGCGGGCGCG TCCTGCCCCC AGGCACCAGT 
CCCCAGGAGC TGTTCCTGTT TGGGGCCAAC TGGACCGTGC ACAATGCGTC CTCCCTGCTC 
ACCTACGATT CCTGGTTCCT GGTCCACAAC TTCCTGTACC AACCCAAGCA CGACCCCACC 
TTCGAGCCCC TCTTCCCCAG TGAGACCACC CTCAACCCCA GCCTGGCACA AGAGGCAGCC 
AAACTATGTG GGGACGATCA TTTCTGCAAC TTTGATGTGG CAGCCACTGG GAGCCTGAGC 
ACGGGCACTG CCACTCGGGT GGCCCACCAG CTGCACCAGC GTCGCATGCA GAGCCTGCAG 
CCAGTGGTGT CCTGTGGCTG GCTGGCCCCA CCTCCCAACG GACAAAAGGA GGGCAACAGG 
TACCTGGCGG GTTCCACCAT CTACTTCCAC TGTGACAACG GCTACAGCCT GGCCGGGGCA 
GAGACCAGCA CCTGCCAGGC TGACGGCACC TGGTCCTCAC CCACCCCGAA GTGCCAGCCA 
GGACGCAGCT ACGCGGTGCT GTTGGGCATC ATCTTTGGGG GCCTCGCGGT GGTGGCGGCG 
GTTGCGCTCG TCTATGTGCT GCTGCGCCGC AGGAAGGGCA ACACGCACGT CTGGGGTGCA 
CAGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SUSD2 ( NM_019601.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_062547.1 Homo sapiens sushi domain containing 2 (SUSD2), mRNA.

Price & Availability↑

CloneID	OHu27875
Clone ID Related Accession (Same CDS sequence)	NM_019601.4 , NM_019601.3
Accession Version	NM_019601.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2469bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-11-01
Organism	Homo sapiens(human)
Product	sushi domain-containing protein 2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC033107.1 and BI822588.1. On Nov 22, 2004 this sequence version replaced NM_019601.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC033107.1, SRR1803612.70429.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGCCAG CCCTCCTGCC CTGGGCCCTG CTGCTGCTGG CGACAGCCCT CGGCCCGGGC 
CCCGGACCCA CAGCAGATGC CCAAGAGAGC TGCTCCATGC GCTGTGGCGC CCTGGACGGG 
CCATGTTCCT GCCACCCGAC GTGCTCTGGC CTTGGCACCT GCTGCTTGGA TTTCCGGGAC 
TTCTGCCTGG AGATATTGCC CTACTCAGGA TCCATGATGG GCGGCAAGGA CTTTGTGGTG 
CGGCACTTCA AGATGTCCAG CCCCACAGAC GCCAGTGTGA TCTGCAGGTT TAAGGACAGC 
ATCCAGACCC TCGGCCATGT GGACTCCTCC GGGCAAGTGC ACTGTGTGTC ACCTCTGCTC 
TATGAGAGCG GCCGCATCCC CTTCACTGTG TCACTGGACA ACGGCCACTC CTTCCCTCGT 
GCGGGCACCT GGCTGGCTGT GCACCCCAAC AAAGTGTCAA TGATGGAGAA GAGCGAGTTG 
GTGAACGAGA CGCGTTGGCA ATACTACGGC ACCGCCAACA CCTCAGGCAA CCTCAGCCTG 
ACCTGGCATG TCAAGTCGCT GCCCACGCAG ACCATCACCA TCGAACTGTG GGGCTACGAG 
GAGACAGGAA TGCCCTACTC ACAGGAGTGG ACTGCAAAGT GGTCGTACCT GTACCCCCTG 
GCCACACACA TCCCCAACTC CGGCTCTTTC ACTTTCACCC CAAAACCTGC TCCTCCCAGC 
TACCAGAGAT GGCGAGTGGG TGCACTTCGG ATCATCGACA GCAAAAATTA CGCAGGGCAG 
AAGGACGTGC AGGCGCTCTG GACCAACGAC CACGCACTGG CCTGGCACCT GAGCGATGAC 
TTCCGAGAGG ACCCTGTGGC CTGGGCACGA ACTCAGTGCC AGGCCTGGGA GGAGCTGGAG 
GATCAGCTGC CCAACTTCCT GGAGGAGCTG CCGGACTGCC CCTGCACCCT GACCCAGGCC 
CGGGCTGACT CCGGCCGCTT CTTCACGGAC TACGGCTGTG ACATGGAGCA GGGCAGCGTG 
TGCACCTACC ACCCCGGGGC CGTGCACTGT GTGCGTTCTG TGCAGGCCAG CCTCCGGTAC 
GGCTCAGGTC AGCAGTGCTG CTACACAGCG GACGGGACGC AGCTCCTGAC AGCTGACTCC 
AGCGGCGGCA GCACTCCCGA CCGCGGCCAT GACTGGGGCG CACCCCCGTT CCGCACGCCA 
CCCCGAGTGC CCAGCATGTC CCACTGGCTC TACGATGTCC TCAGCTTCTA TTACTGCTGC 
CTCTGGGCAC CCGACTGCCC CCGCTACATG CAACGGCGGC CCTCCAATGA CTGCCGCAAC 
TACCGGCCCC CAAGACTGGC CTCCGCCTTC GGAGACCCAC ACTTTGTGAC CTTCGACGGC 
ACCAACTTCA CATTCAATGG GCGCGGAGAG TACGTGCTGC TGGAGGCAGC GCTGACCGAC 
CTGAGGGTGC AGGCGCGGGC CCAGCCCGGG ACGATGTCCA ACGGCACGGA GACCCGTGGC 
ACTGGGCTGA CCGCAGTGGC CGTCCAGGAG GGCAACTCAG ATGTGGTGGA AGTCAGGCTG 
GCCAACAGGA CCGGAGGTCT GGAGGTGCTG CTGAACCAGG AGGTGCTGAG CTTCACCGAG 
CAGAGCTGGA TGGACCTGAA AGGAATGTTC CTGTCGGTGG CTGCCGGGGA CAGGGTCTCC 
ATCATGCTGG CATCAGGGGC CGGCCTGGAG GTCAGCGTGC AGGGCCCGTT CCTGAGTGTG 
TCCGTCCTGC TGCCTGAGAA GTTCCTCACC CACACCCACG GCCTCCTCGG GACACTCAAC 
AACGACCCCA CCGACGACTT CACCCTGCAC AGCGGGCGCG TCCTGCCCCC AGGCACCAGT 
CCCCAGGAGC TGTTCCTGTT TGGGGCCAAC TGGACCGTGC ACAATGCGTC CTCCCTGCTC 
ACCTACGATT CCTGGTTCCT GGTCCACAAC TTCCTGTACC AACCCAAGCA CGACCCCACC 
TTCGAGCCCC TCTTCCCCAG TGAGACCACC CTCAACCCCA GCCTGGCACA AGAGGCAGCC 
AAACTATGTG GGGACGATCA TTTCTGCAAC TTTGATGTGG CAGCCACTGG GAGCCTGAGC 
ACGGGCACTG CCACTCGGGT GGCCCACCAG CTGCACCAGC GTCGCATGCA GAGCCTGCAG 
CCAGTGGTGT CCTGTGGCTG GCTGGCCCCA CCTCCCAACG GACAAAAGGA GGGCAACAGG 
TACCTGGCGG GTTCCACCAT CTACTTCCAC TGTGACAACG GCTACAGCCT GGCCGGGGCA 
GAGACCAGCA CCTGCCAGGC TGACGGCACC TGGTCCTCAC CCACCCCGAA GTGCCAGCCA 
GGACGCAGCT ACGCGGTGCT GTTGGGCATC ATCTTTGGGG GCCTCGCGGT GGTGGCGGCG 
GTTGCGCTCG TCTATGTGCT GCTGCGCCGC AGGAAGGGCA ACACGCACGT CTGGGGTGCA 
CAGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_062547.1
CDS	45..2513
Translation	MKPALLPWALLLLATALGPGPGPTADAQESCSMRCGALDGPCSCHPTCSGLGTCCLDFRDFCLEILPYSGSMMGGKDFVVRHFKMSSPTDASVICRFKDSIQTLGHVDSSGQVHCVSPLLYESGRIPFTVSLDNGHSFPRAGTWLAVHPNKVSMMEKSELVNETRWQYYGTANTSGNLSLTWHVKSLPTQTITIELWGYEETGMPYSQEWTAKWSYLYPLATHIPNSGSFTFTPKPAPPSYQRWRVGALRIIDSKNYAGQKDVQALWTNDHALAWHLSDDFREDPVAWARTQCQAWEELEDQLPNFLEELPDCPCTLTQARADSGRFFTDYGCDMEQGSVCTYHPGAVHCVRSVQASLRYGSGQQCCYTADGTQLLTADSSGGSTPDRGHDWGAPPFRTPPRVPSMSHWLYDVLSFYYCCLWAPDCPRYMQRRPSNDCRNYRPPRLASAFGDPHFVTFDGTNFTFNGRGEYVLLEAALTDLRVQARAQPGTMSNGTETRGTGLTAVAVQEGNSDVVEVRLANRTGGLEVLLNQEVLSFTEQSWMDLKGMFLSVAAGDRVSIMLASGAGLEVSVQGPFLSVSVLLPEKFLTHTHGLLGTLNNDPTDDFTLHSGRVLPPGTSPQELFLFGANWTVHNASSLLTYDSWFLVHNFLYQPKHDPTFEPLFPSETTLNPSLAQEAAKLCGDDHFCNFDVAATGSLSTGTATRVAHQLHQRRMQSLQPVVSCGWLAPPPNGQKEGNRYLAGSTIYFHCDNGYSLAGAETSTCQADGTWSSPTPKCQPGRSYAVLLGIIFGGLAVVAAVALVYVLLRRRKGNTHVWGAQP

Target ORF information:

RefSeq Version	NM_019601.3
Organism	Homo sapiens(human)
Definition	Homo sapiens sushi domain containing 2 (SUSD2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019601.3

ORF Insert Sequence:

ATGAAGCCAG CCCTCCTGCC CTGGGCCCTG CTGCTGCTGG CGACAGCCCT CGGCCCGGGC 
CCCGGACCCA CAGCAGATGC CCAAGAGAGC TGCTCCATGC GCTGTGGCGC CCTGGACGGG 
CCATGTTCCT GCCACCCGAC GTGCTCTGGC CTTGGCACCT GCTGCTTGGA TTTCCGGGAC 
TTCTGCCTGG AGATATTGCC CTACTCAGGA TCCATGATGG GCGGCAAGGA CTTTGTGGTG 
CGGCACTTCA AGATGTCCAG CCCCACAGAC GCCAGTGTGA TCTGCAGGTT TAAGGACAGC 
ATCCAGACCC TCGGCCATGT GGACTCCTCC GGGCAAGTGC ACTGTGTGTC ACCTCTGCTC 
TATGAGAGCG GCCGCATCCC CTTCACTGTG TCACTGGACA ACGGCCACTC CTTCCCTCGT 
GCGGGCACCT GGCTGGCTGT GCACCCCAAC AAAGTGTCAA TGATGGAGAA GAGCGAGTTG 
GTGAACGAGA CGCGTTGGCA ATACTACGGC ACCGCCAACA CCTCAGGCAA CCTCAGCCTG 
ACCTGGCATG TCAAGTCGCT GCCCACGCAG ACCATCACCA TCGAACTGTG GGGCTACGAG 
GAGACAGGAA TGCCCTACTC ACAGGAGTGG ACTGCAAAGT GGTCGTACCT GTACCCCCTG 
GCCACACACA TCCCCAACTC CGGCTCTTTC ACTTTCACCC CAAAACCTGC TCCTCCCAGC 
TACCAGAGAT GGCGAGTGGG TGCACTTCGG ATCATCGACA GCAAAAATTA CGCAGGGCAG 
AAGGACGTGC AGGCGCTCTG GACCAACGAC CACGCACTGG CCTGGCACCT GAGCGATGAC 
TTCCGAGAGG ACCCTGTGGC CTGGGCACGA ACTCAGTGCC AGGCCTGGGA GGAGCTGGAG 
GATCAGCTGC CCAACTTCCT GGAGGAGCTG CCGGACTGCC CCTGCACCCT GACCCAGGCC 
CGGGCTGACT CCGGCCGCTT CTTCACGGAC TACGGCTGTG ACATGGAGCA GGGCAGCGTG 
TGCACCTACC ACCCCGGGGC CGTGCACTGT GTGCGTTCTG TGCAGGCCAG CCTCCGGTAC 
GGCTCAGGTC AGCAGTGCTG CTACACAGCG GACGGGACGC AGCTCCTGAC AGCTGACTCC 
AGCGGCGGCA GCACTCCCGA CCGCGGCCAT GACTGGGGCG CACCCCCGTT CCGCACGCCA 
CCCCGAGTGC CCAGCATGTC CCACTGGCTC TACGATGTCC TCAGCTTCTA TTACTGCTGC 
CTCTGGGCAC CCGACTGCCC CCGCTACATG CAACGGCGGC CCTCCAATGA CTGCCGCAAC 
TACCGGCCCC CAAGACTGGC CTCCGCCTTC GGAGACCCAC ACTTTGTGAC CTTCGACGGC 
ACCAACTTCA CATTCAATGG GCGCGGAGAG TACGTGCTGC TGGAGGCAGC GCTGACCGAC 
CTGAGGGTGC AGGCGCGGGC CCAGCCCGGG ACGATGTCCA ACGGCACGGA GACCCGTGGC 
ACTGGGCTGA CCGCAGTGGC CGTCCAGGAG GGCAACTCAG ATGTGGTGGA AGTCAGGCTG 
GCCAACAGGA CCGGAGGTCT GGAGGTGCTG CTGAACCAGG AGGTGCTGAG CTTCACCGAG 
CAGAGCTGGA TGGACCTGAA AGGAATGTTC CTGTCGGTGG CTGCCGGGGA CAGGGTCTCC 
ATCATGCTGG CATCAGGGGC CGGCCTGGAG GTCAGCGTGC AGGGCCCGTT CCTGAGTGTG 
TCCGTCCTGC TGCCTGAGAA GTTCCTCACC CACACCCACG GCCTCCTCGG GACACTCAAC 
AACGACCCCA CCGACGACTT CACCCTGCAC AGCGGGCGCG TCCTGCCCCC AGGCACCAGT 
CCCCAGGAGC TGTTCCTGTT TGGGGCCAAC TGGACCGTGC ACAATGCGTC CTCCCTGCTC 
ACCTACGATT CCTGGTTCCT GGTCCACAAC TTCCTGTACC AACCCAAGCA CGACCCCACC 
TTCGAGCCCC TCTTCCCCAG TGAGACCACC CTCAACCCCA GCCTGGCACA AGAGGCAGCC 
AAACTATGTG GGGACGATCA TTTCTGCAAC TTTGATGTGG CAGCCACTGG GAGCCTGAGC 
ACGGGCACTG CCACTCGGGT GGCCCACCAG CTGCACCAGC GTCGCATGCA GAGCCTGCAG 
CCAGTGGTGT CCTGTGGCTG GCTGGCCCCA CCTCCCAACG GACAAAAGGA GGGCAACAGG 
TACCTGGCGG GTTCCACCAT CTACTTCCAC TGTGACAACG GCTACAGCCT GGCCGGGGCA 
GAGACCAGCA CCTGCCAGGC TGACGGCACC TGGTCCTCAC CCACCCCGAA GTGCCAGCCA 
GGACGCAGCT ACGCGGTGCT GTTGGGCATC ATCTTTGGGG GCCTCGCGGT GGTGGCGGCG 
GTTGCGCTCG TCTATGTGCT GCTGCGCCGC AGGAAGGGCA ACACGCACGT CTGGGGTGCA 
CAGCCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

SUSD2 promotes tumor-associated macrophage recruitment by increasing levels of MCP-1 in breast cancer.
PloS one12(5)e0177089(2017)
Hultgren EM,Patrick ME,Evans RL,Stoos CT,Egland KA

Downregulation of endometrial mesenchymal marker SUSD2 causes cell senescence and cell death in endometrial carcinoma cells.
PloS one12(8)e0183681(2017)
Zhang S,Zeng N,Alowayed N,Singh Y,Cheng A,Lang F,Salker MS

SUSD2 is frequently downregulated and functions as a tumor suppressor in RCC and lung cancer.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine37(7)9919-30(2016 Jul)
Cheng Y,Wang X,Wang P,Li T,Hu F,Liu Q,Yang F,Wang J,Xu T,Han W

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SUSD2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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