EIF2AK2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	EIF2AK2
Entrez Gene ID	5610
Full Name	eukaryotic translation initiation factor 2 alpha kinase 2
Synonyms	EIF2AK1,PKR,PPP1R83,PRKR
General protein information	Preferred Names eukaryotic translation initiation factor 2 alpha kinase 2 Names interferon-induced, double-stranded RNA-activated protein kinase P1/eIF-2A protein kinase double stranded RNA activated protein kinase eIF-2A protein kinase 2 interferon-inducible elF2alpha kinase p68 kinase protein kinase R protein kinase, interferon-inducible double stranded RNA dependent protein phosphatase 1, regulatory subunit 83 tyrosine-protein kinase EIF2AK2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 2 Map Location: 2p22.2
Summary	The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].
Disorder MIM:	176871

mRNA and Protein(s)

mRNA	Protein	Name
NM_001135651.2	NP_001129123.1	interferon-induced, double-stranded RNA-activated protein kinase isoform a
XM_011532987.1	XP_011531289.1	interferon-induced, double-stranded RNA-activated protein kinase isoform X1
XM_017004503.1	XP_016859992.1	interferon-induced, double-stranded RNA-activated protein kinase isoform X2
NM_001135651.3	NP_001129123.1	interferon-induced, double-stranded RNA-activated protein kinase isoform a
XM_011532987.2	XP_011531289.1	interferon-induced, double-stranded RNA-activated protein kinase isoform X1
NM_002759.3	NP_002750.1	interferon-induced, double-stranded RNA-activated protein kinase isoform a
NM_001135652.2	NP_001129124.1	interferon-induced, double-stranded RNA-activated protein kinase isoform b

Pathways from BioSystems

Homologies

	EIF2AK2	NP_001077417.1
Canis lupus familiaris (dog)	EIF2AK2	NP_001041600.1
Homo sapiens (human)	EIF2AK2	NP_002750.1
Pan troglodytes (chimpanzee)	EIF2AK2	NP_001138509.1
Gallus gallus (chicken)	EIF2AK2	NP_989818.1
Xenopus tropicalis (tropical clawed frog)	pkr3	XP_002933926.1
Bos taurus (cattle)	EIF2AK2	NP_835210.2
Rattus norvegicus (Norway rat)	Eif2ak2	NP_062208.1
Xenopus tropicalis (tropical clawed frog)	eif2ak2	NP_001072537.1
Mus musculus (house mouse)	Eif2ak2	NP_035293.1
Danio rerio (zebrafish)	eif2ak2	NP_001107942.1

Gene Ontology

The following EIF2AK2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the EIF2AK2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu28032	NM_001135651.3 Latest version!	Homo sapiens eukaryotic translation initiation factor 2 alpha kinase 2 (EIF2AK2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu28032	NM_002759.3 Latest version!	Homo sapiens eukaryotic translation initiation factor 2 alpha kinase 2 (EIF2AK2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu28032	XM_011532987.2 Latest version!	Homo sapiens eukaryotic translation initiation factor 2 alpha kinase 2 (EIF2AK2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu28094	NM_001135652.2 Latest version!	Homo sapiens eukaryotic translation initiation factor 2 alpha kinase 2 (EIF2AK2), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu89675	XM_017004503.1 Latest version!	Homo sapiens eukaryotic translation initiation factor 2 alpha kinase 2 (EIF2AK2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
View Old Accession Versions >>
OHu28032	NM_001135651.2	Homo sapiens eukaryotic translation initiation factor 2 alpha kinase 2 (EIF2AK2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu28032	XM_011532987.1	Homo sapiens eukaryotic translation initiation factor 2-alpha kinase 2 (EIF2AK2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

EIF2AK2 ( NM_001135651.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001129123.1 Homo sapiens eukaryotic translation initiation factor 2 alpha kinase 2 (EIF2AK2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu28032
Clone ID Related Accession (Same CDS sequence)	NM_001135651.2 , XM_011532987.1 , NM_001135651.3 , XM_011532987.2 , NM_002759.3
Accession Version	NM_001135651.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1656bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-17
Organism	Homo sapiens(human)
Product	interferon-induced, double-stranded RNA-activated protein kinase isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC040851.1, AC007899.3 and BU687340.1. On Oct 14, 2011 this sequence version replaced NM_001135651.1. Transcript Variant: This variant (2) uses a different splice site in the 5' UTR, compared to variant 1. Variants 1 and 2 both encode the same protein (isoform a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.216303.1, SRR1803616.114352.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTGGTG ATCTTTCAGC AGGTTTCTTC ATGGAGGAAC TTAATACATA CCGTCAGAAG 
CAGGGAGTAG TACTTAAATA TCAAGAACTG CCTAATTCAG GACCTCCACA TGATAGGAGG 
TTTACATTTC AAGTTATAAT AGATGGAAGA GAATTTCCAG AAGGTGAAGG TAGATCAAAG 
AAGGAAGCAA AAAATGCCGC AGCCAAATTA GCTGTTGAGA TACTTAATAA GGAAAAGAAG 
GCAGTTAGTC CTTTATTATT GACAACAACG AATTCTTCAG AAGGATTATC CATGGGGAAT 
TACATAGGCC TTATCAATAG AATTGCCCAG AAGAAAAGAC TAACTGTAAA TTATGAACAG 
TGTGCATCGG GGGTGCATGG GCCAGAAGGA TTTCATTATA AATGCAAAAT GGGACAGAAA 
GAATATAGTA TTGGTACAGG TTCTACTAAA CAGGAAGCAA AACAATTGGC CGCTAAACTT 
GCATATCTTC AGATATTATC AGAAGAAACC TCAGTGAAAT CTGACTACCT GTCCTCTGGT 
TCTTTTGCTA CTACGTGTGA GTCCCAAAGC AACTCTTTAG TGACCAGCAC ACTCGCTTCT 
GAATCATCAT CTGAAGGTGA CTTCTCAGCA GATACATCAG AGATAAATTC TAACAGTGAC 
AGTTTAAACA GTTCTTCGTT GCTTATGAAT GGTCTCAGAA ATAATCAAAG GAAGGCAAAA 
AGATCTTTGG CACCCAGATT TGACCTTCCT GACATGAAAG AAACAAAGTA TACTGTGGAC 
AAGAGGTTTG GCATGGATTT TAAAGAAATA GAATTAATTG GCTCAGGTGG ATTTGGCCAA 
GTTTTCAAAG CAAAACACAG AATTGACGGA AAGACTTACG TTATTAAACG TGTTAAATAT 
AATAACGAGA AGGCGGAGCG TGAAGTAAAA GCATTGGCAA AACTTGATCA TGTAAATATT 
GTTCACTACA ATGGCTGTTG GGATGGATTT GATTATGATC CTGAGACCAG TGATGATTCT 
CTTGAGAGCA GTGATTATGA TCCTGAGAAC AGCAAAAATA GTTCAAGGTC AAAGACTAAG 
TGCCTTTTCA TCCAAATGGA ATTCTGTGAT AAAGGGACCT TGGAACAATG GATTGAAAAA 
AGAAGAGGCG AGAAACTAGA CAAAGTTTTG GCTTTGGAAC TCTTTGAACA AATAACAAAA 
GGGGTGGATT ATATACATTC AAAAAAATTA ATTCATAGAG ATCTTAAGCC AAGTAATATA 
TTCTTAGTAG ATACAAAACA AGTAAAGATT GGAGACTTTG GACTTGTAAC ATCTCTGAAA 
AATGATGGAA AGCGAACAAG GAGTAAGGGA ACTTTGCGAT ACATGAGCCC AGAACAGATT 
TCTTCGCAAG ACTATGGAAA GGAAGTGGAC CTCTACGCTT TGGGGCTAAT TCTTGCTGAA 
CTTCTTCATG TATGTGACAC TGCTTTTGAA ACATCAAAGT TTTTCACAGA CCTACGGGAT 
GGCATCATCT CAGATATATT TGATAAAAAA GAAAAAACTC TTCTACAGAA ATTACTCTCA 
AAGAAACCTG AGGATCGACC TAACACATCT GAAATACTAA GGACCTTGAC TGTGTGGAAG 
AAAAGCCCAG AGAAAAATGA ACGACACACA TGTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001129123.1
CDS	324..1979
Translation	MAGDLSAGFFMEELNTYRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILNKEKKAVSPLLLTTTNSSEGLSMGNYIGLINRIAQKKRLTVNYEQCASGVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLAAKLAYLQILSEETSVKSDYLSSGSFATTCESQSNSLVTSTLASESSSEGDFSADTSEINSNSDSLNSSSLLMNGLRNNQRKAKRSLAPRFDLPDMKETKYTVDKRFGMDFKEIELIGSGGFGQVFKAKHRIDGKTYVIKRVKYNNEKAEREVKALAKLDHVNIVHYNGCWDGFDYDPETSDDSLESSDYDPENSKNSSRSKTKCLFIQMEFCDKGTLEQWIEKRRGEKLDKVLALELFEQITKGVDYIHSKKLIHRDLKPSNIFLVDTKQVKIGDFGLVTSLKNDGKRTRSKGTLRYMSPEQISSQDYGKEVDLYALGLILAELLHVCDTAFETSKFFTDLRDGIISDIFDKKEKTLLQKLLSKKPEDRPNTSEILRTLTVWKKSPEKNERHTC

Target ORF information:

RefSeq Version	NM_001135651.2
Organism	Homo sapiens(human)
Definition	Homo sapiens eukaryotic translation initiation factor 2 alpha kinase 2 (EIF2AK2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001135651.2

ORF Insert Sequence:

ATGGCTGGTG ATCTTTCAGC AGGTTTCTTC ATGGAGGAAC TTAATACATA CCGTCAGAAG 
CAGGGAGTAG TACTTAAATA TCAAGAACTG CCTAATTCAG GACCTCCACA TGATAGGAGG 
TTTACATTTC AAGTTATAAT AGATGGAAGA GAATTTCCAG AAGGTGAAGG TAGATCAAAG 
AAGGAAGCAA AAAATGCCGC AGCCAAATTA GCTGTTGAGA TACTTAATAA GGAAAAGAAG 
GCAGTTAGTC CTTTATTATT GACAACAACG AATTCTTCAG AAGGATTATC CATGGGGAAT 
TACATAGGCC TTATCAATAG AATTGCCCAG AAGAAAAGAC TAACTGTAAA TTATGAACAG 
TGTGCATCGG GGGTGCATGG GCCAGAAGGA TTTCATTATA AATGCAAAAT GGGACAGAAA 
GAATATAGTA TTGGTACAGG TTCTACTAAA CAGGAAGCAA AACAATTGGC CGCTAAACTT 
GCATATCTTC AGATATTATC AGAAGAAACC TCAGTGAAAT CTGACTACCT GTCCTCTGGT 
TCTTTTGCTA CTACGTGTGA GTCCCAAAGC AACTCTTTAG TGACCAGCAC ACTCGCTTCT 
GAATCATCAT CTGAAGGTGA CTTCTCAGCA GATACATCAG AGATAAATTC TAACAGTGAC 
AGTTTAAACA GTTCTTCGTT GCTTATGAAT GGTCTCAGAA ATAATCAAAG GAAGGCAAAA 
AGATCTTTGG CACCCAGATT TGACCTTCCT GACATGAAAG AAACAAAGTA TACTGTGGAC 
AAGAGGTTTG GCATGGATTT TAAAGAAATA GAATTAATTG GCTCAGGTGG ATTTGGCCAA 
GTTTTCAAAG CAAAACACAG AATTGACGGA AAGACTTACG TTATTAAACG TGTTAAATAT 
AATAACGAGA AGGCGGAGCG TGAAGTAAAA GCATTGGCAA AACTTGATCA TGTAAATATT 
GTTCACTACA ATGGCTGTTG GGATGGATTT GATTATGATC CTGAGACCAG TGATGATTCT 
CTTGAGAGCA GTGATTATGA TCCTGAGAAC AGCAAAAATA GTTCAAGGTC AAAGACTAAG 
TGCCTTTTCA TCCAAATGGA ATTCTGTGAT AAAGGGACCT TGGAACAATG GATTGAAAAA 
AGAAGAGGCG AGAAACTAGA CAAAGTTTTG GCTTTGGAAC TCTTTGAACA AATAACAAAA 
GGGGTGGATT ATATACATTC AAAAAAATTA ATTCATAGAG ATCTTAAGCC AAGTAATATA 
TTCTTAGTAG ATACAAAACA AGTAAAGATT GGAGACTTTG GACTTGTAAC ATCTCTGAAA 
AATGATGGAA AGCGAACAAG GAGTAAGGGA ACTTTGCGAT ACATGAGCCC AGAACAGATT 
TCTTCGCAAG ACTATGGAAA GGAAGTGGAC CTCTACGCTT TGGGGCTAAT TCTTGCTGAA 
CTTCTTCATG TATGTGACAC TGCTTTTGAA ACATCAAAGT TTTTCACAGA CCTACGGGAT 
GGCATCATCT CAGATATATT TGATAAAAAA GAAAAAACTC TTCTACAGAA ATTACTCTCA 
AAGAAACCTG AGGATCGACC TAACACATCT GAAATACTAA GGACCTTGAC TGTGTGGAAG 
AAAAGCCCAG AGAAAAATGA ACGACACACA TGTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EIF2AK2 ( NM_001135651.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001129123.1 Homo sapiens eukaryotic translation initiation factor 2 alpha kinase 2 (EIF2AK2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu28032
Clone ID Related Accession (Same CDS sequence)	NM_001135651.2 , XM_011532987.1 , NM_001135651.3 , XM_011532987.2 , NM_002759.3
Accession Version	NM_001135651.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1656bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	interferon-induced, double-stranded RNA-activated protein kinase isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC040851.1, AC007899.3 and BU687340.1. On Nov 22, 2018 this sequence version replaced NM_001135651.2. Transcript Variant: This variant (2) uses a different splice site in the 5' UTR, compared to variant 1. Variants 1 and 2 both encode the same protein (isoform a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.31301.1, SRR1660803.41399.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000233057.9/ ENSP00000233057.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCTGGTG ATCTTTCAGC AGGTTTCTTC ATGGAGGAAC TTAATACATA CCGTCAGAAG 
CAGGGAGTAG TACTTAAATA TCAAGAACTG CCTAATTCAG GACCTCCACA TGATAGGAGG 
TTTACATTTC AAGTTATAAT AGATGGAAGA GAATTTCCAG AAGGTGAAGG TAGATCAAAG 
AAGGAAGCAA AAAATGCCGC AGCCAAATTA GCTGTTGAGA TACTTAATAA GGAAAAGAAG 
GCAGTTAGTC CTTTATTATT GACAACAACG AATTCTTCAG AAGGATTATC CATGGGGAAT 
TACATAGGCC TTATCAATAG AATTGCCCAG AAGAAAAGAC TAACTGTAAA TTATGAACAG 
TGTGCATCGG GGGTGCATGG GCCAGAAGGA TTTCATTATA AATGCAAAAT GGGACAGAAA 
GAATATAGTA TTGGTACAGG TTCTACTAAA CAGGAAGCAA AACAATTGGC CGCTAAACTT 
GCATATCTTC AGATATTATC AGAAGAAACC TCAGTGAAAT CTGACTACCT GTCCTCTGGT 
TCTTTTGCTA CTACGTGTGA GTCCCAAAGC AACTCTTTAG TGACCAGCAC ACTCGCTTCT 
GAATCATCAT CTGAAGGTGA CTTCTCAGCA GATACATCAG AGATAAATTC TAACAGTGAC 
AGTTTAAACA GTTCTTCGTT GCTTATGAAT GGTCTCAGAA ATAATCAAAG GAAGGCAAAA 
AGATCTTTGG CACCCAGATT TGACCTTCCT GACATGAAAG AAACAAAGTA TACTGTGGAC 
AAGAGGTTTG GCATGGATTT TAAAGAAATA GAATTAATTG GCTCAGGTGG ATTTGGCCAA 
GTTTTCAAAG CAAAACACAG AATTGACGGA AAGACTTACG TTATTAAACG TGTTAAATAT 
AATAACGAGA AGGCGGAGCG TGAAGTAAAA GCATTGGCAA AACTTGATCA TGTAAATATT 
GTTCACTACA ATGGCTGTTG GGATGGATTT GATTATGATC CTGAGACCAG TGATGATTCT 
CTTGAGAGCA GTGATTATGA TCCTGAGAAC AGCAAAAATA GTTCAAGGTC AAAGACTAAG 
TGCCTTTTCA TCCAAATGGA ATTCTGTGAT AAAGGGACCT TGGAACAATG GATTGAAAAA 
AGAAGAGGCG AGAAACTAGA CAAAGTTTTG GCTTTGGAAC TCTTTGAACA AATAACAAAA 
GGGGTGGATT ATATACATTC AAAAAAATTA ATTCATAGAG ATCTTAAGCC AAGTAATATA 
TTCTTAGTAG ATACAAAACA AGTAAAGATT GGAGACTTTG GACTTGTAAC ATCTCTGAAA 
AATGATGGAA AGCGAACAAG GAGTAAGGGA ACTTTGCGAT ACATGAGCCC AGAACAGATT 
TCTTCGCAAG ACTATGGAAA GGAAGTGGAC CTCTACGCTT TGGGGCTAAT TCTTGCTGAA 
CTTCTTCATG TATGTGACAC TGCTTTTGAA ACATCAAAGT TTTTCACAGA CCTACGGGAT 
GGCATCATCT CAGATATATT TGATAAAAAA GAAAAAACTC TTCTACAGAA ATTACTCTCA 
AAGAAACCTG AGGATCGACC TAACACATCT GAAATACTAA GGACCTTGAC TGTGTGGAAG 
AAAAGCCCAG AGAAAAATGA ACGACACACA TGTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001129123.1
CDS	257..1912
Translation	MAGDLSAGFFMEELNTYRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILNKEKKAVSPLLLTTTNSSEGLSMGNYIGLINRIAQKKRLTVNYEQCASGVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLAAKLAYLQILSEETSVKSDYLSSGSFATTCESQSNSLVTSTLASESSSEGDFSADTSEINSNSDSLNSSSLLMNGLRNNQRKAKRSLAPRFDLPDMKETKYTVDKRFGMDFKEIELIGSGGFGQVFKAKHRIDGKTYVIKRVKYNNEKAEREVKALAKLDHVNIVHYNGCWDGFDYDPETSDDSLESSDYDPENSKNSSRSKTKCLFIQMEFCDKGTLEQWIEKRRGEKLDKVLALELFEQITKGVDYIHSKKLIHRDLKPSNIFLVDTKQVKIGDFGLVTSLKNDGKRTRSKGTLRYMSPEQISSQDYGKEVDLYALGLILAELLHVCDTAFETSKFFTDLRDGIISDIFDKKEKTLLQKLLSKKPEDRPNTSEILRTLTVWKKSPEKNERHTC

Target ORF information:

RefSeq Version	NM_001135651.3
Organism	Homo sapiens(human)
Definition	Homo sapiens eukaryotic translation initiation factor 2 alpha kinase 2 (EIF2AK2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001135651.3

ORF Insert Sequence:

ATGGCTGGTG ATCTTTCAGC AGGTTTCTTC ATGGAGGAAC TTAATACATA CCGTCAGAAG 
CAGGGAGTAG TACTTAAATA TCAAGAACTG CCTAATTCAG GACCTCCACA TGATAGGAGG 
TTTACATTTC AAGTTATAAT AGATGGAAGA GAATTTCCAG AAGGTGAAGG TAGATCAAAG 
AAGGAAGCAA AAAATGCCGC AGCCAAATTA GCTGTTGAGA TACTTAATAA GGAAAAGAAG 
GCAGTTAGTC CTTTATTATT GACAACAACG AATTCTTCAG AAGGATTATC CATGGGGAAT 
TACATAGGCC TTATCAATAG AATTGCCCAG AAGAAAAGAC TAACTGTAAA TTATGAACAG 
TGTGCATCGG GGGTGCATGG GCCAGAAGGA TTTCATTATA AATGCAAAAT GGGACAGAAA 
GAATATAGTA TTGGTACAGG TTCTACTAAA CAGGAAGCAA AACAATTGGC CGCTAAACTT 
GCATATCTTC AGATATTATC AGAAGAAACC TCAGTGAAAT CTGACTACCT GTCCTCTGGT 
TCTTTTGCTA CTACGTGTGA GTCCCAAAGC AACTCTTTAG TGACCAGCAC ACTCGCTTCT 
GAATCATCAT CTGAAGGTGA CTTCTCAGCA GATACATCAG AGATAAATTC TAACAGTGAC 
AGTTTAAACA GTTCTTCGTT GCTTATGAAT GGTCTCAGAA ATAATCAAAG GAAGGCAAAA 
AGATCTTTGG CACCCAGATT TGACCTTCCT GACATGAAAG AAACAAAGTA TACTGTGGAC 
AAGAGGTTTG GCATGGATTT TAAAGAAATA GAATTAATTG GCTCAGGTGG ATTTGGCCAA 
GTTTTCAAAG CAAAACACAG AATTGACGGA AAGACTTACG TTATTAAACG TGTTAAATAT 
AATAACGAGA AGGCGGAGCG TGAAGTAAAA GCATTGGCAA AACTTGATCA TGTAAATATT 
GTTCACTACA ATGGCTGTTG GGATGGATTT GATTATGATC CTGAGACCAG TGATGATTCT 
CTTGAGAGCA GTGATTATGA TCCTGAGAAC AGCAAAAATA GTTCAAGGTC AAAGACTAAG 
TGCCTTTTCA TCCAAATGGA ATTCTGTGAT AAAGGGACCT TGGAACAATG GATTGAAAAA 
AGAAGAGGCG AGAAACTAGA CAAAGTTTTG GCTTTGGAAC TCTTTGAACA AATAACAAAA 
GGGGTGGATT ATATACATTC AAAAAAATTA ATTCATAGAG ATCTTAAGCC AAGTAATATA 
TTCTTAGTAG ATACAAAACA AGTAAAGATT GGAGACTTTG GACTTGTAAC ATCTCTGAAA 
AATGATGGAA AGCGAACAAG GAGTAAGGGA ACTTTGCGAT ACATGAGCCC AGAACAGATT 
TCTTCGCAAG ACTATGGAAA GGAAGTGGAC CTCTACGCTT TGGGGCTAAT TCTTGCTGAA 
CTTCTTCATG TATGTGACAC TGCTTTTGAA ACATCAAAGT TTTTCACAGA CCTACGGGAT 
GGCATCATCT CAGATATATT TGATAAAAAA GAAAAAACTC TTCTACAGAA ATTACTCTCA 
AAGAAACCTG AGGATCGACC TAACACATCT GAAATACTAA GGACCTTGAC TGTGTGGAAG 
AAAAGCCCAG AGAAAAATGA ACGACACACA TGTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EIF2AK2 ( NM_002759.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_002750.1 Homo sapiens eukaryotic translation initiation factor 2 alpha kinase 2 (EIF2AK2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu28032
Clone ID Related Accession (Same CDS sequence)	NM_001135651.2 , XM_011532987.1 , NM_001135651.3 , XM_011532987.2 , NM_002759.3
Accession Version	NM_002759.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1656bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Homo sapiens(human)
Product	interferon-induced, double-stranded RNA-activated protein kinase isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC040851.1, AC007899.3 and BU687340.1. This sequence is a reference standard in the RefSeqGene project. On Oct 14, 2011 this sequence version replaced NM_002759.2. Transcript Variant: This variant (1) represents the longest transcript. Variants 1 and 2 both encode the same protein (isoform a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: SRR1803611.216303.1, SRR1660809.49056.1 [ECO:0000331] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTGGTG ATCTTTCAGC AGGTTTCTTC ATGGAGGAAC TTAATACATA CCGTCAGAAG 
CAGGGAGTAG TACTTAAATA TCAAGAACTG CCTAATTCAG GACCTCCACA TGATAGGAGG 
TTTACATTTC AAGTTATAAT AGATGGAAGA GAATTTCCAG AAGGTGAAGG TAGATCAAAG 
AAGGAAGCAA AAAATGCCGC AGCCAAATTA GCTGTTGAGA TACTTAATAA GGAAAAGAAG 
GCAGTTAGTC CTTTATTATT GACAACAACG AATTCTTCAG AAGGATTATC CATGGGGAAT 
TACATAGGCC TTATCAATAG AATTGCCCAG AAGAAAAGAC TAACTGTAAA TTATGAACAG 
TGTGCATCGG GGGTGCATGG GCCAGAAGGA TTTCATTATA AATGCAAAAT GGGACAGAAA 
GAATATAGTA TTGGTACAGG TTCTACTAAA CAGGAAGCAA AACAATTGGC CGCTAAACTT 
GCATATCTTC AGATATTATC AGAAGAAACC TCAGTGAAAT CTGACTACCT GTCCTCTGGT 
TCTTTTGCTA CTACGTGTGA GTCCCAAAGC AACTCTTTAG TGACCAGCAC ACTCGCTTCT 
GAATCATCAT CTGAAGGTGA CTTCTCAGCA GATACATCAG AGATAAATTC TAACAGTGAC 
AGTTTAAACA GTTCTTCGTT GCTTATGAAT GGTCTCAGAA ATAATCAAAG GAAGGCAAAA 
AGATCTTTGG CACCCAGATT TGACCTTCCT GACATGAAAG AAACAAAGTA TACTGTGGAC 
AAGAGGTTTG GCATGGATTT TAAAGAAATA GAATTAATTG GCTCAGGTGG ATTTGGCCAA 
GTTTTCAAAG CAAAACACAG AATTGACGGA AAGACTTACG TTATTAAACG TGTTAAATAT 
AATAACGAGA AGGCGGAGCG TGAAGTAAAA GCATTGGCAA AACTTGATCA TGTAAATATT 
GTTCACTACA ATGGCTGTTG GGATGGATTT GATTATGATC CTGAGACCAG TGATGATTCT 
CTTGAGAGCA GTGATTATGA TCCTGAGAAC AGCAAAAATA GTTCAAGGTC AAAGACTAAG 
TGCCTTTTCA TCCAAATGGA ATTCTGTGAT AAAGGGACCT TGGAACAATG GATTGAAAAA 
AGAAGAGGCG AGAAACTAGA CAAAGTTTTG GCTTTGGAAC TCTTTGAACA AATAACAAAA 
GGGGTGGATT ATATACATTC AAAAAAATTA ATTCATAGAG ATCTTAAGCC AAGTAATATA 
TTCTTAGTAG ATACAAAACA AGTAAAGATT GGAGACTTTG GACTTGTAAC ATCTCTGAAA 
AATGATGGAA AGCGAACAAG GAGTAAGGGA ACTTTGCGAT ACATGAGCCC AGAACAGATT 
TCTTCGCAAG ACTATGGAAA GGAAGTGGAC CTCTACGCTT TGGGGCTAAT TCTTGCTGAA 
CTTCTTCATG TATGTGACAC TGCTTTTGAA ACATCAAAGT TTTTCACAGA CCTACGGGAT 
GGCATCATCT CAGATATATT TGATAAAAAA GAAAAAACTC TTCTACAGAA ATTACTCTCA 
AAGAAACCTG AGGATCGACC TAACACATCT GAAATACTAA GGACCTTGAC TGTGTGGAAG 
AAAAGCCCAG AGAAAAATGA ACGACACACA TGTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002750.1
CDS	558..2213
Translation	MAGDLSAGFFMEELNTYRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILNKEKKAVSPLLLTTTNSSEGLSMGNYIGLINRIAQKKRLTVNYEQCASGVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLAAKLAYLQILSEETSVKSDYLSSGSFATTCESQSNSLVTSTLASESSSEGDFSADTSEINSNSDSLNSSSLLMNGLRNNQRKAKRSLAPRFDLPDMKETKYTVDKRFGMDFKEIELIGSGGFGQVFKAKHRIDGKTYVIKRVKYNNEKAEREVKALAKLDHVNIVHYNGCWDGFDYDPETSDDSLESSDYDPENSKNSSRSKTKCLFIQMEFCDKGTLEQWIEKRRGEKLDKVLALELFEQITKGVDYIHSKKLIHRDLKPSNIFLVDTKQVKIGDFGLVTSLKNDGKRTRSKGTLRYMSPEQISSQDYGKEVDLYALGLILAELLHVCDTAFETSKFFTDLRDGIISDIFDKKEKTLLQKLLSKKPEDRPNTSEILRTLTVWKKSPEKNERHTC

Target ORF information:

RefSeq Version	NM_002759.3
Organism	Homo sapiens(human)
Definition	Homo sapiens eukaryotic translation initiation factor 2 alpha kinase 2 (EIF2AK2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002759.3

ORF Insert Sequence:

ATGGCTGGTG ATCTTTCAGC AGGTTTCTTC ATGGAGGAAC TTAATACATA CCGTCAGAAG 
CAGGGAGTAG TACTTAAATA TCAAGAACTG CCTAATTCAG GACCTCCACA TGATAGGAGG 
TTTACATTTC AAGTTATAAT AGATGGAAGA GAATTTCCAG AAGGTGAAGG TAGATCAAAG 
AAGGAAGCAA AAAATGCCGC AGCCAAATTA GCTGTTGAGA TACTTAATAA GGAAAAGAAG 
GCAGTTAGTC CTTTATTATT GACAACAACG AATTCTTCAG AAGGATTATC CATGGGGAAT 
TACATAGGCC TTATCAATAG AATTGCCCAG AAGAAAAGAC TAACTGTAAA TTATGAACAG 
TGTGCATCGG GGGTGCATGG GCCAGAAGGA TTTCATTATA AATGCAAAAT GGGACAGAAA 
GAATATAGTA TTGGTACAGG TTCTACTAAA CAGGAAGCAA AACAATTGGC CGCTAAACTT 
GCATATCTTC AGATATTATC AGAAGAAACC TCAGTGAAAT CTGACTACCT GTCCTCTGGT 
TCTTTTGCTA CTACGTGTGA GTCCCAAAGC AACTCTTTAG TGACCAGCAC ACTCGCTTCT 
GAATCATCAT CTGAAGGTGA CTTCTCAGCA GATACATCAG AGATAAATTC TAACAGTGAC 
AGTTTAAACA GTTCTTCGTT GCTTATGAAT GGTCTCAGAA ATAATCAAAG GAAGGCAAAA 
AGATCTTTGG CACCCAGATT TGACCTTCCT GACATGAAAG AAACAAAGTA TACTGTGGAC 
AAGAGGTTTG GCATGGATTT TAAAGAAATA GAATTAATTG GCTCAGGTGG ATTTGGCCAA 
GTTTTCAAAG CAAAACACAG AATTGACGGA AAGACTTACG TTATTAAACG TGTTAAATAT 
AATAACGAGA AGGCGGAGCG TGAAGTAAAA GCATTGGCAA AACTTGATCA TGTAAATATT 
GTTCACTACA ATGGCTGTTG GGATGGATTT GATTATGATC CTGAGACCAG TGATGATTCT 
CTTGAGAGCA GTGATTATGA TCCTGAGAAC AGCAAAAATA GTTCAAGGTC AAAGACTAAG 
TGCCTTTTCA TCCAAATGGA ATTCTGTGAT AAAGGGACCT TGGAACAATG GATTGAAAAA 
AGAAGAGGCG AGAAACTAGA CAAAGTTTTG GCTTTGGAAC TCTTTGAACA AATAACAAAA 
GGGGTGGATT ATATACATTC AAAAAAATTA ATTCATAGAG ATCTTAAGCC AAGTAATATA 
TTCTTAGTAG ATACAAAACA AGTAAAGATT GGAGACTTTG GACTTGTAAC ATCTCTGAAA 
AATGATGGAA AGCGAACAAG GAGTAAGGGA ACTTTGCGAT ACATGAGCCC AGAACAGATT 
TCTTCGCAAG ACTATGGAAA GGAAGTGGAC CTCTACGCTT TGGGGCTAAT TCTTGCTGAA 
CTTCTTCATG TATGTGACAC TGCTTTTGAA ACATCAAAGT TTTTCACAGA CCTACGGGAT 
GGCATCATCT CAGATATATT TGATAAAAAA GAAAAAACTC TTCTACAGAA ATTACTCTCA 
AAGAAACCTG AGGATCGACC TAACACATCT GAAATACTAA GGACCTTGAC TGTGTGGAAG 
AAAAGCCCAG AGAAAAATGA ACGACACACA TGTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EIF2AK2 ( XM_011532987.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011531289.1 Homo sapiens eukaryotic translation initiation factor 2-alpha kinase 2 (EIF2AK2), transcript variant X1, mRNA.

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CloneID	OHu28032
Clone ID Related Accession (Same CDS sequence)	NM_001135651.2 , XM_011532987.1 , NM_001135651.3 , XM_011532987.2 , NM_002759.3
Accession Version	XM_011532987.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1656bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	interferon-induced, double-stranded RNA-activated protein kinase isoform X1
Comment

ATGGCTGGTG ATCTTTCAGC AGGTTTCTTC ATGGAGGAAC TTAATACATA CCGTCAGAAG 
CAGGGAGTAG TACTTAAATA TCAAGAACTG CCTAATTCAG GACCTCCACA TGATAGGAGG 
TTTACATTTC AAGTTATAAT AGATGGAAGA GAATTTCCAG AAGGTGAAGG TAGATCAAAG 
AAGGAAGCAA AAAATGCCGC AGCCAAATTA GCTGTTGAGA TACTTAATAA GGAAAAGAAG 
GCAGTTAGTC CTTTATTATT GACAACAACG AATTCTTCAG AAGGATTATC CATGGGGAAT 
TACATAGGCC TTATCAATAG AATTGCCCAG AAGAAAAGAC TAACTGTAAA TTATGAACAG 
TGTGCATCGG GGGTGCATGG GCCAGAAGGA TTTCATTATA AATGCAAAAT GGGACAGAAA 
GAATATAGTA TTGGTACAGG TTCTACTAAA CAGGAAGCAA AACAATTGGC CGCTAAACTT 
GCATATCTTC AGATATTATC AGAAGAAACC TCAGTGAAAT CTGACTACCT GTCCTCTGGT 
TCTTTTGCTA CTACGTGTGA GTCCCAAAGC AACTCTTTAG TGACCAGCAC ACTCGCTTCT 
GAATCATCAT CTGAAGGTGA CTTCTCAGCA GATACATCAG AGATAAATTC TAACAGTGAC 
AGTTTAAACA GTTCTTCGTT GCTTATGAAT GGTCTCAGAA ATAATCAAAG GAAGGCAAAA 
AGATCTTTGG CACCCAGATT TGACCTTCCT GACATGAAAG AAACAAAGTA TACTGTGGAC 
AAGAGGTTTG GCATGGATTT TAAAGAAATA GAATTAATTG GCTCAGGTGG ATTTGGCCAA 
GTTTTCAAAG CAAAACACAG AATTGACGGA AAGACTTACG TTATTAAACG TGTTAAATAT 
AATAACGAGA AGGCGGAGCG TGAAGTAAAA GCATTGGCAA AACTTGATCA TGTAAATATT 
GTTCACTACA ATGGCTGTTG GGATGGATTT GATTATGATC CTGAGACCAG TGATGATTCT 
CTTGAGAGCA GTGATTATGA TCCTGAGAAC AGCAAAAATA GTTCAAGGTC AAAGACTAAG 
TGCCTTTTCA TCCAAATGGA ATTCTGTGAT AAAGGGACCT TGGAACAATG GATTGAAAAA 
AGAAGAGGCG AGAAACTAGA CAAAGTTTTG GCTTTGGAAC TCTTTGAACA AATAACAAAA 
GGGGTGGATT ATATACATTC AAAAAAATTA ATTCATAGAG ATCTTAAGCC AAGTAATATA 
TTCTTAGTAG ATACAAAACA AGTAAAGATT GGAGACTTTG GACTTGTAAC ATCTCTGAAA 
AATGATGGAA AGCGAACAAG GAGTAAGGGA ACTTTGCGAT ACATGAGCCC AGAACAGATT 
TCTTCGCAAG ACTATGGAAA GGAAGTGGAC CTCTACGCTT TGGGGCTAAT TCTTGCTGAA 
CTTCTTCATG TATGTGACAC TGCTTTTGAA ACATCAAAGT TTTTCACAGA CCTACGGGAT 
GGCATCATCT CAGATATATT TGATAAAAAA GAAAAAACTC TTCTACAGAA ATTACTCTCA 
AAGAAACCTG AGGATCGACC TAACACATCT GAAATACTAA GGACCTTGAC TGTGTGGAAG 
AAAAGCCCAG AGAAAAATGA ACGACACACA TGTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

XP_011531289.1

Translation

MAGDLSAGFFMEELNTYRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILNKEKKAVSPLLLTTTNSSEGLSMGNYIGLINRIAQKKRLTVNYEQCASGVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLAAKLAYLQILSEETSVKSDYLSSGSFATTCESQSNSLVTSTLASESSSEGDFSADTSEINSNSDSLNSSSLLMNGLRNNQRKAKRSLAPRFDLPDMKETKYTVDKRFGMDFKEIELIGSGGFGQVFKAKHRIDGKTYVIKRVKYNNEKAEREVKALAKLDHVNIVHYNGCWDGFDYDPETSDDSLESSDYDPENSKNSSRSKTKCLFIQMEFCDKGTLEQWIEKRRGEKLDKVLALELFEQITKGVDYIHSKKLIHRDLKPSNIFLVDTKQVKIGDFGLVTSLKNDGKRTRSKGTLRYMSPEQISSQDYGKEVDLYALGLILAELLHVCDTAFETSKFFTDLRDGIISDIFDKKEKTLLQKLLSKKPEDRPNTSEILRTLTVWKKSPEKNERHTC

Target ORF information:

RefSeq Version	XM_011532987.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens eukaryotic translation initiation factor 2-alpha kinase 2 (EIF2AK2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011532987.1

ORF Insert Sequence:

ATGGCTGGTG ATCTTTCAGC AGGTTTCTTC ATGGAGGAAC TTAATACATA CCGTCAGAAG 
CAGGGAGTAG TACTTAAATA TCAAGAACTG CCTAATTCAG GACCTCCACA TGATAGGAGG 
TTTACATTTC AAGTTATAAT AGATGGAAGA GAATTTCCAG AAGGTGAAGG TAGATCAAAG 
AAGGAAGCAA AAAATGCCGC AGCCAAATTA GCTGTTGAGA TACTTAATAA GGAAAAGAAG 
GCAGTTAGTC CTTTATTATT GACAACAACG AATTCTTCAG AAGGATTATC CATGGGGAAT 
TACATAGGCC TTATCAATAG AATTGCCCAG AAGAAAAGAC TAACTGTAAA TTATGAACAG 
TGTGCATCGG GGGTGCATGG GCCAGAAGGA TTTCATTATA AATGCAAAAT GGGACAGAAA 
GAATATAGTA TTGGTACAGG TTCTACTAAA CAGGAAGCAA AACAATTGGC CGCTAAACTT 
GCATATCTTC AGATATTATC AGAAGAAACC TCAGTGAAAT CTGACTACCT GTCCTCTGGT 
TCTTTTGCTA CTACGTGTGA GTCCCAAAGC AACTCTTTAG TGACCAGCAC ACTCGCTTCT 
GAATCATCAT CTGAAGGTGA CTTCTCAGCA GATACATCAG AGATAAATTC TAACAGTGAC 
AGTTTAAACA GTTCTTCGTT GCTTATGAAT GGTCTCAGAA ATAATCAAAG GAAGGCAAAA 
AGATCTTTGG CACCCAGATT TGACCTTCCT GACATGAAAG AAACAAAGTA TACTGTGGAC 
AAGAGGTTTG GCATGGATTT TAAAGAAATA GAATTAATTG GCTCAGGTGG ATTTGGCCAA 
GTTTTCAAAG CAAAACACAG AATTGACGGA AAGACTTACG TTATTAAACG TGTTAAATAT 
AATAACGAGA AGGCGGAGCG TGAAGTAAAA GCATTGGCAA AACTTGATCA TGTAAATATT 
GTTCACTACA ATGGCTGTTG GGATGGATTT GATTATGATC CTGAGACCAG TGATGATTCT 
CTTGAGAGCA GTGATTATGA TCCTGAGAAC AGCAAAAATA GTTCAAGGTC AAAGACTAAG 
TGCCTTTTCA TCCAAATGGA ATTCTGTGAT AAAGGGACCT TGGAACAATG GATTGAAAAA 
AGAAGAGGCG AGAAACTAGA CAAAGTTTTG GCTTTGGAAC TCTTTGAACA AATAACAAAA 
GGGGTGGATT ATATACATTC AAAAAAATTA ATTCATAGAG ATCTTAAGCC AAGTAATATA 
TTCTTAGTAG ATACAAAACA AGTAAAGATT GGAGACTTTG GACTTGTAAC ATCTCTGAAA 
AATGATGGAA AGCGAACAAG GAGTAAGGGA ACTTTGCGAT ACATGAGCCC AGAACAGATT 
TCTTCGCAAG ACTATGGAAA GGAAGTGGAC CTCTACGCTT TGGGGCTAAT TCTTGCTGAA 
CTTCTTCATG TATGTGACAC TGCTTTTGAA ACATCAAAGT TTTTCACAGA CCTACGGGAT 
GGCATCATCT CAGATATATT TGATAAAAAA GAAAAAACTC TTCTACAGAA ATTACTCTCA 
AAGAAACCTG AGGATCGACC TAACACATCT GAAATACTAA GGACCTTGAC TGTGTGGAAG 
AAAAGCCCAG AGAAAAATGA ACGACACACA TGTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EIF2AK2 ( XM_011532987.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011531289.1 Homo sapiens eukaryotic translation initiation factor 2 alpha kinase 2 (EIF2AK2), transcript variant X1, mRNA.

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CloneID	OHu28032
Clone ID Related Accession (Same CDS sequence)	NM_001135651.2 , XM_011532987.1 , NM_001135651.3 , XM_011532987.2 , NM_002759.3
Accession Version	XM_011532987.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1656bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	interferon-induced, double-stranded RNA-activated protein kinase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011532987.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGGTG ATCTTTCAGC AGGTTTCTTC ATGGAGGAAC TTAATACATA CCGTCAGAAG 
CAGGGAGTAG TACTTAAATA TCAAGAACTG CCTAATTCAG GACCTCCACA TGATAGGAGG 
TTTACATTTC AAGTTATAAT AGATGGAAGA GAATTTCCAG AAGGTGAAGG TAGATCAAAG 
AAGGAAGCAA AAAATGCCGC AGCCAAATTA GCTGTTGAGA TACTTAATAA GGAAAAGAAG 
GCAGTTAGTC CTTTATTATT GACAACAACG AATTCTTCAG AAGGATTATC CATGGGGAAT 
TACATAGGCC TTATCAATAG AATTGCCCAG AAGAAAAGAC TAACTGTAAA TTATGAACAG 
TGTGCATCGG GGGTGCATGG GCCAGAAGGA TTTCATTATA AATGCAAAAT GGGACAGAAA 
GAATATAGTA TTGGTACAGG TTCTACTAAA CAGGAAGCAA AACAATTGGC CGCTAAACTT 
GCATATCTTC AGATATTATC AGAAGAAACC TCAGTGAAAT CTGACTACCT GTCCTCTGGT 
TCTTTTGCTA CTACGTGTGA GTCCCAAAGC AACTCTTTAG TGACCAGCAC ACTCGCTTCT 
GAATCATCAT CTGAAGGTGA CTTCTCAGCA GATACATCAG AGATAAATTC TAACAGTGAC 
AGTTTAAACA GTTCTTCGTT GCTTATGAAT GGTCTCAGAA ATAATCAAAG GAAGGCAAAA 
AGATCTTTGG CACCCAGATT TGACCTTCCT GACATGAAAG AAACAAAGTA TACTGTGGAC 
AAGAGGTTTG GCATGGATTT TAAAGAAATA GAATTAATTG GCTCAGGTGG ATTTGGCCAA 
GTTTTCAAAG CAAAACACAG AATTGACGGA AAGACTTACG TTATTAAACG TGTTAAATAT 
AATAACGAGA AGGCGGAGCG TGAAGTAAAA GCATTGGCAA AACTTGATCA TGTAAATATT 
GTTCACTACA ATGGCTGTTG GGATGGATTT GATTATGATC CTGAGACCAG TGATGATTCT 
CTTGAGAGCA GTGATTATGA TCCTGAGAAC AGCAAAAATA GTTCAAGGTC AAAGACTAAG 
TGCCTTTTCA TCCAAATGGA ATTCTGTGAT AAAGGGACCT TGGAACAATG GATTGAAAAA 
AGAAGAGGCG AGAAACTAGA CAAAGTTTTG GCTTTGGAAC TCTTTGAACA AATAACAAAA 
GGGGTGGATT ATATACATTC AAAAAAATTA ATTCATAGAG ATCTTAAGCC AAGTAATATA 
TTCTTAGTAG ATACAAAACA AGTAAAGATT GGAGACTTTG GACTTGTAAC ATCTCTGAAA 
AATGATGGAA AGCGAACAAG GAGTAAGGGA ACTTTGCGAT ACATGAGCCC AGAACAGATT 
TCTTCGCAAG ACTATGGAAA GGAAGTGGAC CTCTACGCTT TGGGGCTAAT TCTTGCTGAA 
CTTCTTCATG TATGTGACAC TGCTTTTGAA ACATCAAAGT TTTTCACAGA CCTACGGGAT 
GGCATCATCT CAGATATATT TGATAAAAAA GAAAAAACTC TTCTACAGAA ATTACTCTCA 
AAGAAACCTG AGGATCGACC TAACACATCT GAAATACTAA GGACCTTGAC TGTGTGGAAG 
AAAAGCCCAG AGAAAAATGA ACGACACACA TGTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011531289.1
CDS	258..1913
Translation	MAGDLSAGFFMEELNTYRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILNKEKKAVSPLLLTTTNSSEGLSMGNYIGLINRIAQKKRLTVNYEQCASGVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLAAKLAYLQILSEETSVKSDYLSSGSFATTCESQSNSLVTSTLASESSSEGDFSADTSEINSNSDSLNSSSLLMNGLRNNQRKAKRSLAPRFDLPDMKETKYTVDKRFGMDFKEIELIGSGGFGQVFKAKHRIDGKTYVIKRVKYNNEKAEREVKALAKLDHVNIVHYNGCWDGFDYDPETSDDSLESSDYDPENSKNSSRSKTKCLFIQMEFCDKGTLEQWIEKRRGEKLDKVLALELFEQITKGVDYIHSKKLIHRDLKPSNIFLVDTKQVKIGDFGLVTSLKNDGKRTRSKGTLRYMSPEQISSQDYGKEVDLYALGLILAELLHVCDTAFETSKFFTDLRDGIISDIFDKKEKTLLQKLLSKKPEDRPNTSEILRTLTVWKKSPEKNERHTC

Target ORF information:

RefSeq Version	XM_011532987.2
Organism	Homo sapiens(human)
Definition	Homo sapiens eukaryotic translation initiation factor 2 alpha kinase 2 (EIF2AK2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011532987.2

ORF Insert Sequence:

ATGGCTGGTG ATCTTTCAGC AGGTTTCTTC ATGGAGGAAC TTAATACATA CCGTCAGAAG 
CAGGGAGTAG TACTTAAATA TCAAGAACTG CCTAATTCAG GACCTCCACA TGATAGGAGG 
TTTACATTTC AAGTTATAAT AGATGGAAGA GAATTTCCAG AAGGTGAAGG TAGATCAAAG 
AAGGAAGCAA AAAATGCCGC AGCCAAATTA GCTGTTGAGA TACTTAATAA GGAAAAGAAG 
GCAGTTAGTC CTTTATTATT GACAACAACG AATTCTTCAG AAGGATTATC CATGGGGAAT 
TACATAGGCC TTATCAATAG AATTGCCCAG AAGAAAAGAC TAACTGTAAA TTATGAACAG 
TGTGCATCGG GGGTGCATGG GCCAGAAGGA TTTCATTATA AATGCAAAAT GGGACAGAAA 
GAATATAGTA TTGGTACAGG TTCTACTAAA CAGGAAGCAA AACAATTGGC CGCTAAACTT 
GCATATCTTC AGATATTATC AGAAGAAACC TCAGTGAAAT CTGACTACCT GTCCTCTGGT 
TCTTTTGCTA CTACGTGTGA GTCCCAAAGC AACTCTTTAG TGACCAGCAC ACTCGCTTCT 
GAATCATCAT CTGAAGGTGA CTTCTCAGCA GATACATCAG AGATAAATTC TAACAGTGAC 
AGTTTAAACA GTTCTTCGTT GCTTATGAAT GGTCTCAGAA ATAATCAAAG GAAGGCAAAA 
AGATCTTTGG CACCCAGATT TGACCTTCCT GACATGAAAG AAACAAAGTA TACTGTGGAC 
AAGAGGTTTG GCATGGATTT TAAAGAAATA GAATTAATTG GCTCAGGTGG ATTTGGCCAA 
GTTTTCAAAG CAAAACACAG AATTGACGGA AAGACTTACG TTATTAAACG TGTTAAATAT 
AATAACGAGA AGGCGGAGCG TGAAGTAAAA GCATTGGCAA AACTTGATCA TGTAAATATT 
GTTCACTACA ATGGCTGTTG GGATGGATTT GATTATGATC CTGAGACCAG TGATGATTCT 
CTTGAGAGCA GTGATTATGA TCCTGAGAAC AGCAAAAATA GTTCAAGGTC AAAGACTAAG 
TGCCTTTTCA TCCAAATGGA ATTCTGTGAT AAAGGGACCT TGGAACAATG GATTGAAAAA 
AGAAGAGGCG AGAAACTAGA CAAAGTTTTG GCTTTGGAAC TCTTTGAACA AATAACAAAA 
GGGGTGGATT ATATACATTC AAAAAAATTA ATTCATAGAG ATCTTAAGCC AAGTAATATA 
TTCTTAGTAG ATACAAAACA AGTAAAGATT GGAGACTTTG GACTTGTAAC ATCTCTGAAA 
AATGATGGAA AGCGAACAAG GAGTAAGGGA ACTTTGCGAT ACATGAGCCC AGAACAGATT 
TCTTCGCAAG ACTATGGAAA GGAAGTGGAC CTCTACGCTT TGGGGCTAAT TCTTGCTGAA 
CTTCTTCATG TATGTGACAC TGCTTTTGAA ACATCAAAGT TTTTCACAGA CCTACGGGAT 
GGCATCATCT CAGATATATT TGATAAAAAA GAAAAAACTC TTCTACAGAA ATTACTCTCA 
AAGAAACCTG AGGATCGACC TAACACATCT GAAATACTAA GGACCTTGAC TGTGTGGAAG 
AAAAGCCCAG AGAAAAATGA ACGACACACA TGTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EIF2AK2 ( NM_001135652.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001129124.1 Homo sapiens eukaryotic translation initiation factor 2 alpha kinase 2 (EIF2AK2), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu28094
Clone ID Related Accession (Same CDS sequence)	NM_001135652.2
Accession Version	NM_001135652.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1533bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Homo sapiens(human)
Product	interferon-induced, double-stranded RNA-activated protein kinase isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC101475.1, AC007899.3 and BU687340.1. On Oct 14, 2011 this sequence version replaced NM_001135652.1. Transcript Variant: This variant (3) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a. The 5' UTR splice pattern of this transcript has not been determined. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY302136.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCTGGTG ATCTTTCAGC AGGTTTCTTC ATGGAGGAAC TTAATACATA CCGTCAGAAG 
CAGGGAGTAG TACTTAAATA TCAAGAACTG CCTAATTCAG GACCTCCACA TGATAGGAGG 
TTTACATTTC AAGTTATAAT AGATGGAAGA GAATTTCCAG AAGGTGAAGG TAGATCAAAG 
AAGGAAGCAA AAAATGCCGC AGCCAAATTA GCTGTTGAGA TACTTAATAA GGAAAAGAAG 
GCAGTTAGTC CTTTATTATT GACAACAACG AATTCTTCAG AAGGATTATC CATGGGGAAT 
TACATAGGCC TTATCAATAG AATTGCCCAG AAGAAAAGAC TAACTGTAAA TTATGAACAG 
TGTGCATCGG GGGTGCATGG GCCAGAAGGA TTTCATTATA AATGCAAAAT GGGACAGAAA 
GAATATAGTA TTGGTACAGG TTCTACTAAA CAGGAAGCAA AACAATTGGC CGCTAAACTT 
GCATATCTTC AGATATTATC AGAAGAAACC TCAGTGAAAT CTGACTACCT GTCCTCTGGT 
TCTTTTGCTA CTACGTGTGA GTCCCAAAGC AACTCTTTAG TGACCAGCAC ACTCGCTTCT 
GAATCATCAT CTGAAGGTGA CTTCTCAGCA GATACATCAG AGATAAATTC TAACAGTGAC 
AGTTTAAACA GTTCTTCGTT GCTTATGAAT GGTCTCAGAA ATAATCAAAG GAAGGCAAAA 
AGATCTTTGG CACCCAGATT TGACCTTCCT GACATGAAAG AAACAAAGTA TACTGTGGAC 
AAGAGGAAGG CGGAGCGTGA AGTAAAAGCA TTGGCAAAAC TTGATCATGT AAATATTGTT 
CACTACAATG GCTGTTGGGA TGGATTTGAT TATGATCCTG AGACCAGTGA TGATTCTCTT 
GAGAGCAGTG ATTATGATCC TGAGAACAGC AAAAATAGTT CAAGGTCAAA GACTAAGTGC 
CTTTTCATCC AAATGGAATT CTGTGATAAA GGGACCTTGG AACAATGGAT TGAAAAAAGA 
AGAGGCGAGA AACTAGACAA AGTTTTGGCT TTGGAACTCT TTGAACAAAT AACAAAAGGG 
GTGGATTATA TACATTCAAA AAAATTAATT CATAGAGATC TTAAGCCAAG TAATATATTC 
TTAGTAGATA CAAAACAAGT AAAGATTGGA GACTTTGGAC TTGTAACATC TCTGAAAAAT 
GATGGAAAGC GAACAAGGAG TAAGGGAACT TTGCGATACA TGAGCCCAGA ACAGATTTCT 
TCGCAAGACT ATGGAAAGGA AGTGGACCTC TACGCTTTGG GGCTAATTCT TGCTGAACTT 
CTTCATGTAT GTGACACTGC TTTTGAAACA TCAAAGTTTT TCACAGACCT ACGGGATGGC 
ATCATCTCAG ATATATTTGA TAAAAAAGAA AAAACTCTTC TACAGAAATT ACTCTCAAAG 
AAACCTGAGG ATCGACCTAA CACATCTGAA ATACTAAGGA CCTTGACTGT GTGGAAGAAA 
AGCCCAGAGA AAAATGAACG ACACACATGT TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001129124.1
CDS	17..1549
Translation	MAGDLSAGFFMEELNTYRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILNKEKKAVSPLLLTTTNSSEGLSMGNYIGLINRIAQKKRLTVNYEQCASGVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLAAKLAYLQILSEETSVKSDYLSSGSFATTCESQSNSLVTSTLASESSSEGDFSADTSEINSNSDSLNSSSLLMNGLRNNQRKAKRSLAPRFDLPDMKETKYTVDKRKAEREVKALAKLDHVNIVHYNGCWDGFDYDPETSDDSLESSDYDPENSKNSSRSKTKCLFIQMEFCDKGTLEQWIEKRRGEKLDKVLALELFEQITKGVDYIHSKKLIHRDLKPSNIFLVDTKQVKIGDFGLVTSLKNDGKRTRSKGTLRYMSPEQISSQDYGKEVDLYALGLILAELLHVCDTAFETSKFFTDLRDGIISDIFDKKEKTLLQKLLSKKPEDRPNTSEILRTLTVWKKSPEKNERHTC

Target ORF information:

RefSeq Version	NM_001135652.2
Organism	Homo sapiens(human)
Definition	Homo sapiens eukaryotic translation initiation factor 2 alpha kinase 2 (EIF2AK2), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001135652.2

ORF Insert Sequence:

ATGGCTGGTG ATCTTTCAGC AGGTTTCTTC ATGGAGGAAC TTAATACATA CCGTCAGAAG 
CAGGGAGTAG TACTTAAATA TCAAGAACTG CCTAATTCAG GACCTCCACA TGATAGGAGG 
TTTACATTTC AAGTTATAAT AGATGGAAGA GAATTTCCAG AAGGTGAAGG TAGATCAAAG 
AAGGAAGCAA AAAATGCCGC AGCCAAATTA GCTGTTGAGA TACTTAATAA GGAAAAGAAG 
GCAGTTAGTC CTTTATTATT GACAACAACG AATTCTTCAG AAGGATTATC CATGGGGAAT 
TACATAGGCC TTATCAATAG AATTGCCCAG AAGAAAAGAC TAACTGTAAA TTATGAACAG 
TGTGCATCGG GGGTGCATGG GCCAGAAGGA TTTCATTATA AATGCAAAAT GGGACAGAAA 
GAATATAGTA TTGGTACAGG TTCTACTAAA CAGGAAGCAA AACAATTGGC CGCTAAACTT 
GCATATCTTC AGATATTATC AGAAGAAACC TCAGTGAAAT CTGACTACCT GTCCTCTGGT 
TCTTTTGCTA CTACGTGTGA GTCCCAAAGC AACTCTTTAG TGACCAGCAC ACTCGCTTCT 
GAATCATCAT CTGAAGGTGA CTTCTCAGCA GATACATCAG AGATAAATTC TAACAGTGAC 
AGTTTAAACA GTTCTTCGTT GCTTATGAAT GGTCTCAGAA ATAATCAAAG GAAGGCAAAA 
AGATCTTTGG CACCCAGATT TGACCTTCCT GACATGAAAG AAACAAAGTA TACTGTGGAC 
AAGAGGAAGG CGGAGCGTGA AGTAAAAGCA TTGGCAAAAC TTGATCATGT AAATATTGTT 
CACTACAATG GCTGTTGGGA TGGATTTGAT TATGATCCTG AGACCAGTGA TGATTCTCTT 
GAGAGCAGTG ATTATGATCC TGAGAACAGC AAAAATAGTT CAAGGTCAAA GACTAAGTGC 
CTTTTCATCC AAATGGAATT CTGTGATAAA GGGACCTTGG AACAATGGAT TGAAAAAAGA 
AGAGGCGAGA AACTAGACAA AGTTTTGGCT TTGGAACTCT TTGAACAAAT AACAAAAGGG 
GTGGATTATA TACATTCAAA AAAATTAATT CATAGAGATC TTAAGCCAAG TAATATATTC 
TTAGTAGATA CAAAACAAGT AAAGATTGGA GACTTTGGAC TTGTAACATC TCTGAAAAAT 
GATGGAAAGC GAACAAGGAG TAAGGGAACT TTGCGATACA TGAGCCCAGA ACAGATTTCT 
TCGCAAGACT ATGGAAAGGA AGTGGACCTC TACGCTTTGG GGCTAATTCT TGCTGAACTT 
CTTCATGTAT GTGACACTGC TTTTGAAACA TCAAAGTTTT TCACAGACCT ACGGGATGGC 
ATCATCTCAG ATATATTTGA TAAAAAAGAA AAAACTCTTC TACAGAAATT ACTCTCAAAG 
AAACCTGAGG ATCGACCTAA CACATCTGAA ATACTAAGGA CCTTGACTGT GTGGAAGAAA 
AGCCCAGAGA AAAATGAACG ACACACATGT TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EIF2AK2 ( XM_017004503.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016859992.1 Homo sapiens eukaryotic translation initiation factor 2 alpha kinase 2 (EIF2AK2), transcript variant X2, mRNA.

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CloneID	OHu89675
Clone ID Related Accession (Same CDS sequence)	XM_017004503.1
Accession Version	XM_017004503.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1527bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	interferon-induced, double-stranded RNA-activated protein kinase isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGGTG ATCTTTCAGC AGGTTTCTTC ATGGAGGAAC TTAATACATA CCGTCAGAAG 
CAGGGAGTAG TACTTAAATA TCAAGAACTG CCTAATTCAG GACCTCCACA TGATAGGAGG 
TTTACATTTC AAGTTATAAT AGATGGAAGA GAATTTCCAG AAGGTGAAGG TAGATCAAAG 
AAGGAAGCAA AAAATGCCGC AGCCAAATTA GCTGTTGAGA TACTTAATAA GGAAAAGAAG 
GCAGTTAGTC CTTTATTATT GACAACAACG AATTCTTCAG AAGGATTATC CATGGGGAAT 
TACATAGGCC TTATCAATAG AATTGCCCAG AAGAAAAGAC TAACTGTAAA TTATGAACAG 
TGTGCATCGG GGGTGCATGG GCCAGAAGGA TTTCATTATA AATGCAAAAT GGGACAGAAA 
GAATATAGTA TTGGTACAGG TTCTACTAAA CAGGAAGCAA AACAATTGGC CGCTAAACTT 
GCATATCTTC AGATATTATC AGAAGAAACC TCAGTGAAAT CTGACTACCT GTCCTCTGGT 
TCTTTTGCTA CTACGTGTGA GTCCCAAAGC AACTCTTTAG TGACCAGCAC ACTCGCTTCT 
GAATCATCAT CTGAAGGTGA CTTCTCAGCA GATACATCAG AGATAAATTC TAACAGTGAC 
AGTTTAAACA GTTCTTCGTT GCTTATGAAT GGTCTCAGAA ATAATCAAAG GAAGGCAAAA 
AGATCTTTGG CACCCAGATT TGACCTTCCT GACATGAAAG AAACAAAGTA TACTGTGGAC 
AAGAGGTTTG GCATGGATTT TAAAGAAATA GAATTAATTG GCTCAGGTGG ATTTGGCCAA 
GTTTTCAAAG CAAAACACAG AATTGACGGA AAGACTTACG TTATTAAACG TGTTAAATAT 
AATAACGAGA AGGCGGAGCG TGAAGTAAAA GCATTGGCAA AACTTGATCA TGTAAATATT 
GTTCACTACA ATGGCTGTTG GGATGGATTT GATTATGATC CTGAGACCAG TGATGATTCT 
CTTGAGAGCA GTGATTATGA TCCTGAGAAC AGCAAAAATA GTTCAAGGTC AAAGACTAAG 
TGCCTTTTCA TCCAAATGGA ATTCTGTGAT AAAGGGACCT TGGAACAATG GATTGAAAAA 
AGAAGAGGCG AGAAACTAGA CAAAGTTTTG GCTTTGGAAC TCTTTGAACA AATAACAAAA 
GGGGTGGATT ATATACATTC AAAAAAATTA ATTCATAGAG ATCTTAAGAT TTCTTCGCAA 
GACTATGGAA AGGAAGTGGA CCTCTACGCT TTGGGGCTAA TTCTTGCTGA ACTTCTTCAT 
GTATGTGACA CTGCTTTTGA AACATCAAAG TTTTTCACAG ACCTACGGGA TGGCATCATC 
TCAGATATAT TTGATAAAAA AGAAAAAACT CTTCTACAGA AATTACTCTC AAAGAAACCT 
GAGGATCGAC CTAACACATC TGAAATACTA AGGACCTTGA CTGTGTGGAA GAAAAGCCCA 
GAGAAAAATG AACGACACAC ATGTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016859992.1
CDS	254..1780
Translation	MAGDLSAGFFMEELNTYRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILNKEKKAVSPLLLTTTNSSEGLSMGNYIGLINRIAQKKRLTVNYEQCASGVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLAAKLAYLQILSEETSVKSDYLSSGSFATTCESQSNSLVTSTLASESSSEGDFSADTSEINSNSDSLNSSSLLMNGLRNNQRKAKRSLAPRFDLPDMKETKYTVDKRFGMDFKEIELIGSGGFGQVFKAKHRIDGKTYVIKRVKYNNEKAEREVKALAKLDHVNIVHYNGCWDGFDYDPETSDDSLESSDYDPENSKNSSRSKTKCLFIQMEFCDKGTLEQWIEKRRGEKLDKVLALELFEQITKGVDYIHSKKLIHRDLKISSQDYGKEVDLYALGLILAELLHVCDTAFETSKFFTDLRDGIISDIFDKKEKTLLQKLLSKKPEDRPNTSEILRTLTVWKKSPEKNERHTC

Target ORF information:

RefSeq Version	XM_017004503.1
Organism	Homo sapiens(human)
Definition	Homo sapiens eukaryotic translation initiation factor 2 alpha kinase 2 (EIF2AK2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017004503.1

ORF Insert Sequence:

ATGGCTGGTG ATCTTTCAGC AGGTTTCTTC ATGGAGGAAC TTAATACATA CCGTCAGAAG 
CAGGGAGTAG TACTTAAATA TCAAGAACTG CCTAATTCAG GACCTCCACA TGATAGGAGG 
TTTACATTTC AAGTTATAAT AGATGGAAGA GAATTTCCAG AAGGTGAAGG TAGATCAAAG 
AAGGAAGCAA AAAATGCCGC AGCCAAATTA GCTGTTGAGA TACTTAATAA GGAAAAGAAG 
GCAGTTAGTC CTTTATTATT GACAACAACG AATTCTTCAG AAGGATTATC CATGGGGAAT 
TACATAGGCC TTATCAATAG AATTGCCCAG AAGAAAAGAC TAACTGTAAA TTATGAACAG 
TGTGCATCGG GGGTGCATGG GCCAGAAGGA TTTCATTATA AATGCAAAAT GGGACAGAAA 
GAATATAGTA TTGGTACAGG TTCTACTAAA CAGGAAGCAA AACAATTGGC CGCTAAACTT 
GCATATCTTC AGATATTATC AGAAGAAACC TCAGTGAAAT CTGACTACCT GTCCTCTGGT 
TCTTTTGCTA CTACGTGTGA GTCCCAAAGC AACTCTTTAG TGACCAGCAC ACTCGCTTCT 
GAATCATCAT CTGAAGGTGA CTTCTCAGCA GATACATCAG AGATAAATTC TAACAGTGAC 
AGTTTAAACA GTTCTTCGTT GCTTATGAAT GGTCTCAGAA ATAATCAAAG GAAGGCAAAA 
AGATCTTTGG CACCCAGATT TGACCTTCCT GACATGAAAG AAACAAAGTA TACTGTGGAC 
AAGAGGTTTG GCATGGATTT TAAAGAAATA GAATTAATTG GCTCAGGTGG ATTTGGCCAA 
GTTTTCAAAG CAAAACACAG AATTGACGGA AAGACTTACG TTATTAAACG TGTTAAATAT 
AATAACGAGA AGGCGGAGCG TGAAGTAAAA GCATTGGCAA AACTTGATCA TGTAAATATT 
GTTCACTACA ATGGCTGTTG GGATGGATTT GATTATGATC CTGAGACCAG TGATGATTCT 
CTTGAGAGCA GTGATTATGA TCCTGAGAAC AGCAAAAATA GTTCAAGGTC AAAGACTAAG 
TGCCTTTTCA TCCAAATGGA ATTCTGTGAT AAAGGGACCT TGGAACAATG GATTGAAAAA 
AGAAGAGGCG AGAAACTAGA CAAAGTTTTG GCTTTGGAAC TCTTTGAACA AATAACAAAA 
GGGGTGGATT ATATACATTC AAAAAAATTA ATTCATAGAG ATCTTAAGAT TTCTTCGCAA 
GACTATGGAA AGGAAGTGGA CCTCTACGCT TTGGGGCTAA TTCTTGCTGA ACTTCTTCAT 
GTATGTGACA CTGCTTTTGA AACATCAAAG TTTTTCACAG ACCTACGGGA TGGCATCATC 
TCAGATATAT TTGATAAAAA AGAAAAAACT CTTCTACAGA AATTACTCTC AAAGAAACCT 
GAGGATCGAC CTAACACATC TGAAATACTA AGGACCTTGA CTGTGTGGAA GAAAAGCCCA 
GAGAAAAATG AACGACACAC ATGTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

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EIF2AK2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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FAX

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