MAP2K1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	MAP2K1
Entrez Gene ID	5604
Full Name	mitogen-activated protein kinase kinase 1
Synonyms	CFC3,MAPKK1,MEK1,MKK1,PRKMK1
General protein information	Preferred Names mitogen-activated protein kinase kinase 1 Names dual specificity mitogen-activated protein kinase kinase 1 ERK activator kinase 1 MAPK/ERK kinase 1 MAPKK 1 MEK 1 protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1)
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 15 Map Location: 15q22.31
Summary	The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development. [provided by RefSeq, Jul 2008].
Disorder MIM:	176872
Disorder Html:	Cardiofaciocutaneous syndrome 3, 615279 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_002755.3	NP_002746.1	dual specificity mitogen-activated protein kinase kinase 1
XM_017022413.1	XP_016877902.1	dual specificity mitogen-activated protein kinase kinase 1 isoform X4
XM_017022412.1	XP_016877901.1	dual specificity mitogen-activated protein kinase kinase 1 isoform X3
XM_011521783.3	XP_011520085.1	dual specificity mitogen-activated protein kinase kinase 1 isoform X1
XM_017022411.1	XP_016877900.1	dual specificity mitogen-activated protein kinase kinase 1 isoform X2
XM_017022411.2	XP_016877900.1	dual specificity mitogen-activated protein kinase kinase 1 isoform X2
NM_002755.4	NP_002746.1	dual specificity mitogen-activated protein kinase kinase 1
XM_011521783.2	XP_011520085.1	dual specificity mitogen-activated protein kinase kinase 1 isoform X1

Pathways from BioSystems

Homologies

Schizosaccharomyces pombe (fission yeast)	byr1	NP_593026.1
Neurospora crassa	NCU04612	XP_958855.1
Xenopus tropicalis (tropical clawed frog)	map2k1	NP_001008058.1
Homo sapiens (human)	MAP2K1	NP_002746.1
	MAP2K1	XP_001110225.1
Mus musculus (house mouse)	Map2k1	NP_032953.1
Danio rerio (zebrafish)	map2k1	NP_998584.2
Oryza sativa (rice)	Os06g0147800	NP_001056806.1
Pan troglodytes (chimpanzee)	MAP2K1	NP_001009071.1
Caenorhabditis elegans (roundworm)	mek-2	NP_491087.1
Magnaporthe oryzae (rice blast fungus)	MGG_00800	XP_003718185.1
Bos taurus (cattle)	MAP2K1	NP_001124224.1
Rattus norvegicus (Norway rat)	Map2k1	NP_113831.1
Drosophila melanogaster (fruit fly)	Dsor1	NP_511098.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001103	XP_322064.4
Arabidopsis thaliana (thale cress)	MEK1	NP_974619.1
Arabidopsis thaliana (thale cress)	MKK2	NP_194710.1
Canis lupus familiaris (dog)	MAP2K1	NP_001041559.1
Gallus gallus (chicken)	MAP2K1	NP_001005830.1

Gene Ontology

The following MAP2K1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MAP2K1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu27418	NM_002755.4 Latest version!	Homo sapiens mitogen-activated protein kinase kinase 1 (MAP2K1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu59946	XM_011521783.3 Latest version!	Homo sapiens mitogen-activated protein kinase kinase 1 (MAP2K1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu85562	XM_017022411.2 Latest version!	Homo sapiens mitogen-activated protein kinase kinase 1 (MAP2K1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu85563	XM_017022412.1 Latest version!	Homo sapiens mitogen-activated protein kinase kinase 1 (MAP2K1), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu85564	XM_017022413.1 Latest version!	Homo sapiens mitogen-activated protein kinase kinase 1 (MAP2K1), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OHu85562	XM_017022411.1	Homo sapiens mitogen-activated protein kinase kinase 1 (MAP2K1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu27418	NM_002755.3	Homo sapiens mitogen-activated protein kinase kinase 1 (MAP2K1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu59946	XM_011521783.2	Homo sapiens mitogen-activated protein kinase kinase 1 (MAP2K1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MAP2K1 ( NM_002755.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_002746.1 Homo sapiens mitogen-activated protein kinase kinase 1 (MAP2K1), mRNA.

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CloneID	OHu27418
Clone ID Related Accession (Same CDS sequence)	NM_002755.3 , NM_002755.4
Accession Version	NM_002755.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1182bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-03
Organism	Homo sapiens(human)
Product	dual specificity mitogen-activated protein kinase kinase 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA653983.1, AK291500.1, AK312356.1, L11284.1, BG709050.1 and CA419665.1. This sequence is a reference standard in the RefSeqGene project. On Mar 12, 2008 this sequence version replaced NM_002755.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.92418.1, SRR1163657.64664.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCCCAAGA AGAAGCCGAC GCCCATCCAG CTGAACCCGG CCCCCGACGG CTCTGCAGTT 
AACGGGACCA GCTCTGCGGA GACCAACTTG GAGGCCTTGC AGAAGAAGCT GGAGGAGCTA 
GAGCTTGATG AGCAGCAGCG AAAGCGCCTT GAGGCCTTTC TTACCCAGAA GCAGAAGGTG 
GGAGAACTGA AGGATGACGA CTTTGAGAAG ATCAGTGAGC TGGGGGCTGG CAATGGCGGT 
GTGGTGTTCA AGGTCTCCCA CAAGCCTTCT GGCCTGGTCA TGGCCAGAAA GCTAATTCAT 
CTGGAGATCA AACCCGCAAT CCGGAACCAG ATCATAAGGG AGCTGCAGGT TCTGCATGAG 
TGCAACTCTC CGTACATCGT GGGCTTCTAT GGTGCGTTCT ACAGCGATGG CGAGATCAGT 
ATCTGCATGG AGCACATGGA TGGAGGTTCT CTGGATCAAG TCCTGAAGAA AGCTGGAAGA 
ATTCCTGAAC AAATTTTAGG AAAAGTTAGC ATTGCTGTAA TAAAAGGCCT GACATATCTG 
AGGGAGAAGC ACAAGATCAT GCACAGAGAT GTCAAGCCCT CCAACATCCT AGTCAACTCC 
CGTGGGGAGA TCAAGCTCTG TGACTTTGGG GTCAGCGGGC AGCTCATCGA CTCCATGGCC 
AACTCCTTCG TGGGCACAAG GTCCTACATG TCGCCAGAAA GACTCCAGGG GACTCATTAC 
TCTGTGCAGT CAGACATCTG GAGCATGGGA CTGTCTCTGG TAGAGATGGC GGTTGGGAGG 
TATCCCATCC CTCCTCCAGA TGCCAAGGAG CTGGAGCTGA TGTTTGGGTG CCAGGTGGAA 
GGAGATGCGG CTGAGACCCC ACCCAGGCCA AGGACCCCCG GGAGGCCCCT TAGCTCATAC 
GGAATGGACA GCCGACCTCC CATGGCAATT TTTGAGTTGT TGGATTACAT AGTCAACGAG 
CCTCCTCCAA AACTGCCCAG TGGAGTGTTC AGTCTGGAAT TTCAAGATTT TGTGAATAAA 
TGCTTAATAA AAAACCCCGC AGAGAGAGCA GATTTGAAGC AACTCATGGT TCATGCTTTT 
ATCAAGAGAT CTGATGCTGA GGAAGTGGAT TTTGCAGGTT GGCTCTGCTC CACCATCGGC 
CTTAACCAGC CCAGCACACC AACCCATGCT GCTGGCGTCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002746.1
CDS	476..1657
Translation	MPKKKPTPIQLNPAPDGSAVNGTSSAETNLEALQKKLEELELDEQQRKRLEAFLTQKQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGCQVEGDAAETPPRPRTPGRPLSSYGMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIGLNQPSTPTHAAGV

Target ORF information:

RefSeq Version	NM_002755.3
Organism	Homo sapiens(human)
Definition	Homo sapiens mitogen-activated protein kinase kinase 1 (MAP2K1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002755.3

ORF Insert Sequence:

ATGCCCAAGA AGAAGCCGAC GCCCATCCAG CTGAACCCGG CCCCCGACGG CTCTGCAGTT 
AACGGGACCA GCTCTGCGGA GACCAACTTG GAGGCCTTGC AGAAGAAGCT GGAGGAGCTA 
GAGCTTGATG AGCAGCAGCG AAAGCGCCTT GAGGCCTTTC TTACCCAGAA GCAGAAGGTG 
GGAGAACTGA AGGATGACGA CTTTGAGAAG ATCAGTGAGC TGGGGGCTGG CAATGGCGGT 
GTGGTGTTCA AGGTCTCCCA CAAGCCTTCT GGCCTGGTCA TGGCCAGAAA GCTAATTCAT 
CTGGAGATCA AACCCGCAAT CCGGAACCAG ATCATAAGGG AGCTGCAGGT TCTGCATGAG 
TGCAACTCTC CGTACATCGT GGGCTTCTAT GGTGCGTTCT ACAGCGATGG CGAGATCAGT 
ATCTGCATGG AGCACATGGA TGGAGGTTCT CTGGATCAAG TCCTGAAGAA AGCTGGAAGA 
ATTCCTGAAC AAATTTTAGG AAAAGTTAGC ATTGCTGTAA TAAAAGGCCT GACATATCTG 
AGGGAGAAGC ACAAGATCAT GCACAGAGAT GTCAAGCCCT CCAACATCCT AGTCAACTCC 
CGTGGGGAGA TCAAGCTCTG TGACTTTGGG GTCAGCGGGC AGCTCATCGA CTCCATGGCC 
AACTCCTTCG TGGGCACAAG GTCCTACATG TCGCCAGAAA GACTCCAGGG GACTCATTAC 
TCTGTGCAGT CAGACATCTG GAGCATGGGA CTGTCTCTGG TAGAGATGGC GGTTGGGAGG 
TATCCCATCC CTCCTCCAGA TGCCAAGGAG CTGGAGCTGA TGTTTGGGTG CCAGGTGGAA 
GGAGATGCGG CTGAGACCCC ACCCAGGCCA AGGACCCCCG GGAGGCCCCT TAGCTCATAC 
GGAATGGACA GCCGACCTCC CATGGCAATT TTTGAGTTGT TGGATTACAT AGTCAACGAG 
CCTCCTCCAA AACTGCCCAG TGGAGTGTTC AGTCTGGAAT TTCAAGATTT TGTGAATAAA 
TGCTTAATAA AAAACCCCGC AGAGAGAGCA GATTTGAAGC AACTCATGGT TCATGCTTTT 
ATCAAGAGAT CTGATGCTGA GGAAGTGGAT TTTGCAGGTT GGCTCTGCTC CACCATCGGC 
CTTAACCAGC CCAGCACACC AACCCATGCT GCTGGCGTCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MAP2K1 ( NM_002755.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_002746.1 Homo sapiens mitogen-activated protein kinase kinase 1 (MAP2K1), mRNA.

Price & Availability↑

CloneID	OHu27418
Clone ID Related Accession (Same CDS sequence)	NM_002755.3 , NM_002755.4
Accession Version	NM_002755.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1182bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-19
Organism	Homo sapiens(human)
Product	dual specificity mitogen-activated protein kinase kinase 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK291500.1, AK312356.1, L11284.1, BG709050.1 and CA419665.1. On Nov 22, 2019 this sequence version replaced NM_002755.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK291500.1, L11284.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCCCAAGA AGAAGCCGAC GCCCATCCAG CTGAACCCGG CCCCCGACGG CTCTGCAGTT 
AACGGGACCA GCTCTGCGGA GACCAACTTG GAGGCCTTGC AGAAGAAGCT GGAGGAGCTA 
GAGCTTGATG AGCAGCAGCG AAAGCGCCTT GAGGCCTTTC TTACCCAGAA GCAGAAGGTG 
GGAGAACTGA AGGATGACGA CTTTGAGAAG ATCAGTGAGC TGGGGGCTGG CAATGGCGGT 
GTGGTGTTCA AGGTCTCCCA CAAGCCTTCT GGCCTGGTCA TGGCCAGAAA GCTAATTCAT 
CTGGAGATCA AACCCGCAAT CCGGAACCAG ATCATAAGGG AGCTGCAGGT TCTGCATGAG 
TGCAACTCTC CGTACATCGT GGGCTTCTAT GGTGCGTTCT ACAGCGATGG CGAGATCAGT 
ATCTGCATGG AGCACATGGA TGGAGGTTCT CTGGATCAAG TCCTGAAGAA AGCTGGAAGA 
ATTCCTGAAC AAATTTTAGG AAAAGTTAGC ATTGCTGTAA TAAAAGGCCT GACATATCTG 
AGGGAGAAGC ACAAGATCAT GCACAGAGAT GTCAAGCCCT CCAACATCCT AGTCAACTCC 
CGTGGGGAGA TCAAGCTCTG TGACTTTGGG GTCAGCGGGC AGCTCATCGA CTCCATGGCC 
AACTCCTTCG TGGGCACAAG GTCCTACATG TCGCCAGAAA GACTCCAGGG GACTCATTAC 
TCTGTGCAGT CAGACATCTG GAGCATGGGA CTGTCTCTGG TAGAGATGGC GGTTGGGAGG 
TATCCCATCC CTCCTCCAGA TGCCAAGGAG CTGGAGCTGA TGTTTGGGTG CCAGGTGGAA 
GGAGATGCGG CTGAGACCCC ACCCAGGCCA AGGACCCCCG GGAGGCCCCT TAGCTCATAC 
GGAATGGACA GCCGACCTCC CATGGCAATT TTTGAGTTGT TGGATTACAT AGTCAACGAG 
CCTCCTCCAA AACTGCCCAG TGGAGTGTTC AGTCTGGAAT TTCAAGATTT TGTGAATAAA 
TGCTTAATAA AAAACCCCGC AGAGAGAGCA GATTTGAAGC AACTCATGGT TCATGCTTTT 
ATCAAGAGAT CTGATGCTGA GGAAGTGGAT TTTGCAGGTT GGCTCTGCTC CACCATCGGC 
CTTAACCAGC CCAGCACACC AACCCATGCT GCTGGCGTCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002746.1
CDS	437..1618
Translation	MPKKKPTPIQLNPAPDGSAVNGTSSAETNLEALQKKLEELELDEQQRKRLEAFLTQKQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGCQVEGDAAETPPRPRTPGRPLSSYGMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIGLNQPSTPTHAAGV

Target ORF information:

RefSeq Version	NM_002755.4
Organism	Homo sapiens(human)
Definition	Homo sapiens mitogen-activated protein kinase kinase 1 (MAP2K1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002755.4

ORF Insert Sequence:

ATGCCCAAGA AGAAGCCGAC GCCCATCCAG CTGAACCCGG CCCCCGACGG CTCTGCAGTT 
AACGGGACCA GCTCTGCGGA GACCAACTTG GAGGCCTTGC AGAAGAAGCT GGAGGAGCTA 
GAGCTTGATG AGCAGCAGCG AAAGCGCCTT GAGGCCTTTC TTACCCAGAA GCAGAAGGTG 
GGAGAACTGA AGGATGACGA CTTTGAGAAG ATCAGTGAGC TGGGGGCTGG CAATGGCGGT 
GTGGTGTTCA AGGTCTCCCA CAAGCCTTCT GGCCTGGTCA TGGCCAGAAA GCTAATTCAT 
CTGGAGATCA AACCCGCAAT CCGGAACCAG ATCATAAGGG AGCTGCAGGT TCTGCATGAG 
TGCAACTCTC CGTACATCGT GGGCTTCTAT GGTGCGTTCT ACAGCGATGG CGAGATCAGT 
ATCTGCATGG AGCACATGGA TGGAGGTTCT CTGGATCAAG TCCTGAAGAA AGCTGGAAGA 
ATTCCTGAAC AAATTTTAGG AAAAGTTAGC ATTGCTGTAA TAAAAGGCCT GACATATCTG 
AGGGAGAAGC ACAAGATCAT GCACAGAGAT GTCAAGCCCT CCAACATCCT AGTCAACTCC 
CGTGGGGAGA TCAAGCTCTG TGACTTTGGG GTCAGCGGGC AGCTCATCGA CTCCATGGCC 
AACTCCTTCG TGGGCACAAG GTCCTACATG TCGCCAGAAA GACTCCAGGG GACTCATTAC 
TCTGTGCAGT CAGACATCTG GAGCATGGGA CTGTCTCTGG TAGAGATGGC GGTTGGGAGG 
TATCCCATCC CTCCTCCAGA TGCCAAGGAG CTGGAGCTGA TGTTTGGGTG CCAGGTGGAA 
GGAGATGCGG CTGAGACCCC ACCCAGGCCA AGGACCCCCG GGAGGCCCCT TAGCTCATAC 
GGAATGGACA GCCGACCTCC CATGGCAATT TTTGAGTTGT TGGATTACAT AGTCAACGAG 
CCTCCTCCAA AACTGCCCAG TGGAGTGTTC AGTCTGGAAT TTCAAGATTT TGTGAATAAA 
TGCTTAATAA AAAACCCCGC AGAGAGAGCA GATTTGAAGC AACTCATGGT TCATGCTTTT 
ATCAAGAGAT CTGATGCTGA GGAAGTGGAT TTTGCAGGTT GGCTCTGCTC CACCATCGGC 
CTTAACCAGC CCAGCACACC AACCCATGCT GCTGGCGTCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MAP2K1 ( XM_011521783.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_011520085.1 Homo sapiens mitogen-activated protein kinase kinase 1 (MAP2K1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu59946
Clone ID Related Accession (Same CDS sequence)	XM_011521783.3 , XM_011521783.2
Accession Version	XM_011521783.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1116bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	dual specificity mitogen-activated protein kinase kinase 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000015.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011521783.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGCTGG AGAGGACCAA CTTGGAGGCC TTGCAGAAGA AGCTGGAGGA GCTAGAGCTT 
GATGAGCAGC AGCGAAAGCG CCTTGAGGCC TTTCTTACCC AGAAGCAGAA GGTGGGAGAA 
CTGAAGGATG ACGACTTTGA GAAGATCAGT GAGCTGGGGG CTGGCAATGG CGGTGTGGTG 
TTCAAGGTCT CCCACAAGCC TTCTGGCCTG GTCATGGCCA GAAAGCTAAT TCATCTGGAG 
ATCAAACCCG CAATCCGGAA CCAGATCATA AGGGAGCTGC AGGTTCTGCA TGAGTGCAAC 
TCTCCGTACA TCGTGGGCTT CTATGGTGCG TTCTACAGCG ATGGCGAGAT CAGTATCTGC 
ATGGAGCACA TGGATGGAGG TTCTCTGGAT CAAGTCCTGA AGAAAGCTGG AAGAATTCCT 
GAACAAATTT TAGGAAAAGT TAGCATTGCT GTAATAAAAG GCCTGACATA TCTGAGGGAG 
AAGCACAAGA TCATGCACAG AGATGTCAAG CCCTCCAACA TCCTAGTCAA CTCCCGTGGG 
GAGATCAAGC TCTGTGACTT TGGGGTCAGC GGGCAGCTCA TCGACTCCAT GGCCAACTCC 
TTCGTGGGCA CAAGGTCCTA CATGTCGCCA GAAAGACTCC AGGGGACTCA TTACTCTGTG 
CAGTCAGACA TCTGGAGCAT GGGACTGTCT CTGGTAGAGA TGGCGGTTGG GAGGTATCCC 
ATCCCTCCTC CAGATGCCAA GGAGCTGGAG CTGATGTTTG GGTGCCAGGT GGAAGGAGAT 
GCGGCTGAGA CCCCACCCAG GCCAAGGACC CCCGGGAGGC CCCTTAGCTC ATACGGAATG 
GACAGCCGAC CTCCCATGGC AATTTTTGAG TTGTTGGATT ACATAGTCAA CGAGCCTCCT 
CCAAAACTGC CCAGTGGAGT GTTCAGTCTG GAATTTCAAG ATTTTGTGAA TAAATGCTTA 
ATAAAAAACC CCGCAGAGAG AGCAGATTTG AAGCAACTCA TGGTTCATGC TTTTATCAAG 
AGATCTGATG CTGAGGAAGT GGATTTTGCA GGTTGGCTCT GCTCCACCAT CGGCCTTAAC 
CAGCCCAGCA CACCAACCCA TGCTGCTGGC GTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011520085.1
CDS	195..1310
Translation	MKLERTNLEALQKKLEELELDEQQRKRLEAFLTQKQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGCQVEGDAAETPPRPRTPGRPLSSYGMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIGLNQPSTPTHAAGV

Target ORF information:

RefSeq Version	XM_011521783.3
Organism	Homo sapiens(human)
Definition	Homo sapiens mitogen-activated protein kinase kinase 1 (MAP2K1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011521783.3

ORF Insert Sequence:

ATGAAGCTGG AGAGGACCAA CTTGGAGGCC TTGCAGAAGA AGCTGGAGGA GCTAGAGCTT 
GATGAGCAGC AGCGAAAGCG CCTTGAGGCC TTTCTTACCC AGAAGCAGAA GGTGGGAGAA 
CTGAAGGATG ACGACTTTGA GAAGATCAGT GAGCTGGGGG CTGGCAATGG CGGTGTGGTG 
TTCAAGGTCT CCCACAAGCC TTCTGGCCTG GTCATGGCCA GAAAGCTAAT TCATCTGGAG 
ATCAAACCCG CAATCCGGAA CCAGATCATA AGGGAGCTGC AGGTTCTGCA TGAGTGCAAC 
TCTCCGTACA TCGTGGGCTT CTATGGTGCG TTCTACAGCG ATGGCGAGAT CAGTATCTGC 
ATGGAGCACA TGGATGGAGG TTCTCTGGAT CAAGTCCTGA AGAAAGCTGG AAGAATTCCT 
GAACAAATTT TAGGAAAAGT TAGCATTGCT GTAATAAAAG GCCTGACATA TCTGAGGGAG 
AAGCACAAGA TCATGCACAG AGATGTCAAG CCCTCCAACA TCCTAGTCAA CTCCCGTGGG 
GAGATCAAGC TCTGTGACTT TGGGGTCAGC GGGCAGCTCA TCGACTCCAT GGCCAACTCC 
TTCGTGGGCA CAAGGTCCTA CATGTCGCCA GAAAGACTCC AGGGGACTCA TTACTCTGTG 
CAGTCAGACA TCTGGAGCAT GGGACTGTCT CTGGTAGAGA TGGCGGTTGG GAGGTATCCC 
ATCCCTCCTC CAGATGCCAA GGAGCTGGAG CTGATGTTTG GGTGCCAGGT GGAAGGAGAT 
GCGGCTGAGA CCCCACCCAG GCCAAGGACC CCCGGGAGGC CCCTTAGCTC ATACGGAATG 
GACAGCCGAC CTCCCATGGC AATTTTTGAG TTGTTGGATT ACATAGTCAA CGAGCCTCCT 
CCAAAACTGC CCAGTGGAGT GTTCAGTCTG GAATTTCAAG ATTTTGTGAA TAAATGCTTA 
ATAAAAAACC CCGCAGAGAG AGCAGATTTG AAGCAACTCA TGGTTCATGC TTTTATCAAG 
AGATCTGATG CTGAGGAAGT GGATTTTGCA GGTTGGCTCT GCTCCACCAT CGGCCTTAAC 
CAGCCCAGCA CACCAACCCA TGCTGCTGGC GTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MAP2K1 ( XM_011521783.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011520085.1 Homo sapiens mitogen-activated protein kinase kinase 1 (MAP2K1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu59946
Clone ID Related Accession (Same CDS sequence)	XM_011521783.3 , XM_011521783.2
Accession Version	XM_011521783.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1116bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	dual specificity mitogen-activated protein kinase kinase 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000015.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011521783.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGCTGG AGAGGACCAA CTTGGAGGCC TTGCAGAAGA AGCTGGAGGA GCTAGAGCTT 
GATGAGCAGC AGCGAAAGCG CCTTGAGGCC TTTCTTACCC AGAAGCAGAA GGTGGGAGAA 
CTGAAGGATG ACGACTTTGA GAAGATCAGT GAGCTGGGGG CTGGCAATGG CGGTGTGGTG 
TTCAAGGTCT CCCACAAGCC TTCTGGCCTG GTCATGGCCA GAAAGCTAAT TCATCTGGAG 
ATCAAACCCG CAATCCGGAA CCAGATCATA AGGGAGCTGC AGGTTCTGCA TGAGTGCAAC 
TCTCCGTACA TCGTGGGCTT CTATGGTGCG TTCTACAGCG ATGGCGAGAT CAGTATCTGC 
ATGGAGCACA TGGATGGAGG TTCTCTGGAT CAAGTCCTGA AGAAAGCTGG AAGAATTCCT 
GAACAAATTT TAGGAAAAGT TAGCATTGCT GTAATAAAAG GCCTGACATA TCTGAGGGAG 
AAGCACAAGA TCATGCACAG AGATGTCAAG CCCTCCAACA TCCTAGTCAA CTCCCGTGGG 
GAGATCAAGC TCTGTGACTT TGGGGTCAGC GGGCAGCTCA TCGACTCCAT GGCCAACTCC 
TTCGTGGGCA CAAGGTCCTA CATGTCGCCA GAAAGACTCC AGGGGACTCA TTACTCTGTG 
CAGTCAGACA TCTGGAGCAT GGGACTGTCT CTGGTAGAGA TGGCGGTTGG GAGGTATCCC 
ATCCCTCCTC CAGATGCCAA GGAGCTGGAG CTGATGTTTG GGTGCCAGGT GGAAGGAGAT 
GCGGCTGAGA CCCCACCCAG GCCAAGGACC CCCGGGAGGC CCCTTAGCTC ATACGGAATG 
GACAGCCGAC CTCCCATGGC AATTTTTGAG TTGTTGGATT ACATAGTCAA CGAGCCTCCT 
CCAAAACTGC CCAGTGGAGT GTTCAGTCTG GAATTTCAAG ATTTTGTGAA TAAATGCTTA 
ATAAAAAACC CCGCAGAGAG AGCAGATTTG AAGCAACTCA TGGTTCATGC TTTTATCAAG 
AGATCTGATG CTGAGGAAGT GGATTTTGCA GGTTGGCTCT GCTCCACCAT CGGCCTTAAC 
CAGCCCAGCA CACCAACCCA TGCTGCTGGC GTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011520085.1
CDS	199..1314
Translation	MKLERTNLEALQKKLEELELDEQQRKRLEAFLTQKQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGCQVEGDAAETPPRPRTPGRPLSSYGMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIGLNQPSTPTHAAGV

Target ORF information:

RefSeq Version	XM_011521783.2
Organism	Homo sapiens(human)
Definition	Homo sapiens mitogen-activated protein kinase kinase 1 (MAP2K1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011521783.2

ORF Insert Sequence:

ATGAAGCTGG AGAGGACCAA CTTGGAGGCC TTGCAGAAGA AGCTGGAGGA GCTAGAGCTT 
GATGAGCAGC AGCGAAAGCG CCTTGAGGCC TTTCTTACCC AGAAGCAGAA GGTGGGAGAA 
CTGAAGGATG ACGACTTTGA GAAGATCAGT GAGCTGGGGG CTGGCAATGG CGGTGTGGTG 
TTCAAGGTCT CCCACAAGCC TTCTGGCCTG GTCATGGCCA GAAAGCTAAT TCATCTGGAG 
ATCAAACCCG CAATCCGGAA CCAGATCATA AGGGAGCTGC AGGTTCTGCA TGAGTGCAAC 
TCTCCGTACA TCGTGGGCTT CTATGGTGCG TTCTACAGCG ATGGCGAGAT CAGTATCTGC 
ATGGAGCACA TGGATGGAGG TTCTCTGGAT CAAGTCCTGA AGAAAGCTGG AAGAATTCCT 
GAACAAATTT TAGGAAAAGT TAGCATTGCT GTAATAAAAG GCCTGACATA TCTGAGGGAG 
AAGCACAAGA TCATGCACAG AGATGTCAAG CCCTCCAACA TCCTAGTCAA CTCCCGTGGG 
GAGATCAAGC TCTGTGACTT TGGGGTCAGC GGGCAGCTCA TCGACTCCAT GGCCAACTCC 
TTCGTGGGCA CAAGGTCCTA CATGTCGCCA GAAAGACTCC AGGGGACTCA TTACTCTGTG 
CAGTCAGACA TCTGGAGCAT GGGACTGTCT CTGGTAGAGA TGGCGGTTGG GAGGTATCCC 
ATCCCTCCTC CAGATGCCAA GGAGCTGGAG CTGATGTTTG GGTGCCAGGT GGAAGGAGAT 
GCGGCTGAGA CCCCACCCAG GCCAAGGACC CCCGGGAGGC CCCTTAGCTC ATACGGAATG 
GACAGCCGAC CTCCCATGGC AATTTTTGAG TTGTTGGATT ACATAGTCAA CGAGCCTCCT 
CCAAAACTGC CCAGTGGAGT GTTCAGTCTG GAATTTCAAG ATTTTGTGAA TAAATGCTTA 
ATAAAAAACC CCGCAGAGAG AGCAGATTTG AAGCAACTCA TGGTTCATGC TTTTATCAAG 
AGATCTGATG CTGAGGAAGT GGATTTTGCA GGTTGGCTCT GCTCCACCAT CGGCCTTAAC 
CAGCCCAGCA CACCAACCCA TGCTGCTGGC GTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MAP2K1 ( XM_017022411.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016877900.1 Homo sapiens mitogen-activated protein kinase kinase 1 (MAP2K1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu85562
Clone ID Related Accession (Same CDS sequence)	XM_017022411.1 , XM_017022411.2
Accession Version	XM_017022411.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1104bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	dual specificity mitogen-activated protein kinase kinase 1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000015.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCCAAGA AGAAGCCGAC GCCCATCCAG CTGAACCCGG CCCCCGACGG CTCTGCAGTT 
AACGGGACCA GCTCTGCGGA GACCAACTTG GAGGCCTTGC AGAAGAAGCT GGAGGAGCTA 
GAGCTTGATG AGCAGCAGCG AAAGCGCCTT GAGGCCTTTC TTACCCAGAA GCAGAAGGTG 
GGAGAACTGA AGGATGACGA CTTTGAGAAG ATCAGTGAGC TGGGGGCTGG CAATGGCGGT 
GTGGTGTTCA AGGTCTCCCA CAAGCCTTCT GGCCTGGTCA TGGCCAGAAA GCTAATTCAT 
CTGGAGATCA AACCCGCAAT CCGGAACCAG ATCATAAGGG AGCTGCAGGT TCTGCATGAG 
TGCAACTCTC CGTACATCGT GGGCTTCTAT GGTGCGTTCT ACAGCGATGG CGAGATCAGT 
ATCTGCATGG AGCACATGGT AATAAAAGGC CTGACATATC TGAGGGAGAA GCACAAGATC 
ATGCACAGAG ATGTCAAGCC CTCCAACATC CTAGTCAACT CCCGTGGGGA GATCAAGCTC 
TGTGACTTTG GGGTCAGCGG GCAGCTCATC GACTCCATGG CCAACTCCTT CGTGGGCACA 
AGGTCCTACA TGTCGCCAGA AAGACTCCAG GGGACTCATT ACTCTGTGCA GTCAGACATC 
TGGAGCATGG GACTGTCTCT GGTAGAGATG GCGGTTGGGA GGTATCCCAT CCCTCCTCCA 
GATGCCAAGG AGCTGGAGCT GATGTTTGGG TGCCAGGTGG AAGGAGATGC GGCTGAGACC 
CCACCCAGGC CAAGGACCCC CGGGAGGCCC CTTAGCTCAT ACGGAATGGA CAGCCGACCT 
CCCATGGCAA TTTTTGAGTT GTTGGATTAC ATAGTCAACG AGCCTCCTCC AAAACTGCCC 
AGTGGAGTGT TCAGTCTGGA ATTTCAAGAT TTTGTGAATA AATGCTTAAT AAAAAACCCC 
GCAGAGAGAG CAGATTTGAA GCAACTCATG GTTCATGCTT TTATCAAGAG ATCTGATGCT 
GAGGAAGTGG ATTTTGCAGG TTGGCTCTGC TCCACCATCG GCCTTAACCA GCCCAGCACA 
CCAACCCATG CTGCTGGCGT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016877900.1
CDS	427..1530
Translation	MPKKKPTPIQLNPAPDGSAVNGTSSAETNLEALQKKLEELELDEQQRKRLEAFLTQKQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGCQVEGDAAETPPRPRTPGRPLSSYGMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIGLNQPSTPTHAAGV

Target ORF information:

RefSeq Version	XM_017022411.1
Organism	Homo sapiens(human)
Definition	Homo sapiens mitogen-activated protein kinase kinase 1 (MAP2K1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017022411.1

ORF Insert Sequence:

ATGCCCAAGA AGAAGCCGAC GCCCATCCAG CTGAACCCGG CCCCCGACGG CTCTGCAGTT 
AACGGGACCA GCTCTGCGGA GACCAACTTG GAGGCCTTGC AGAAGAAGCT GGAGGAGCTA 
GAGCTTGATG AGCAGCAGCG AAAGCGCCTT GAGGCCTTTC TTACCCAGAA GCAGAAGGTG 
GGAGAACTGA AGGATGACGA CTTTGAGAAG ATCAGTGAGC TGGGGGCTGG CAATGGCGGT 
GTGGTGTTCA AGGTCTCCCA CAAGCCTTCT GGCCTGGTCA TGGCCAGAAA GCTAATTCAT 
CTGGAGATCA AACCCGCAAT CCGGAACCAG ATCATAAGGG AGCTGCAGGT TCTGCATGAG 
TGCAACTCTC CGTACATCGT GGGCTTCTAT GGTGCGTTCT ACAGCGATGG CGAGATCAGT 
ATCTGCATGG AGCACATGGT AATAAAAGGC CTGACATATC TGAGGGAGAA GCACAAGATC 
ATGCACAGAG ATGTCAAGCC CTCCAACATC CTAGTCAACT CCCGTGGGGA GATCAAGCTC 
TGTGACTTTG GGGTCAGCGG GCAGCTCATC GACTCCATGG CCAACTCCTT CGTGGGCACA 
AGGTCCTACA TGTCGCCAGA AAGACTCCAG GGGACTCATT ACTCTGTGCA GTCAGACATC 
TGGAGCATGG GACTGTCTCT GGTAGAGATG GCGGTTGGGA GGTATCCCAT CCCTCCTCCA 
GATGCCAAGG AGCTGGAGCT GATGTTTGGG TGCCAGGTGG AAGGAGATGC GGCTGAGACC 
CCACCCAGGC CAAGGACCCC CGGGAGGCCC CTTAGCTCAT ACGGAATGGA CAGCCGACCT 
CCCATGGCAA TTTTTGAGTT GTTGGATTAC ATAGTCAACG AGCCTCCTCC AAAACTGCCC 
AGTGGAGTGT TCAGTCTGGA ATTTCAAGAT TTTGTGAATA AATGCTTAAT AAAAAACCCC 
GCAGAGAGAG CAGATTTGAA GCAACTCATG GTTCATGCTT TTATCAAGAG ATCTGATGCT 
GAGGAAGTGG ATTTTGCAGG TTGGCTCTGC TCCACCATCG GCCTTAACCA GCCCAGCACA 
CCAACCCATG CTGCTGGCGT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MAP2K1 ( XM_017022411.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_016877900.1 Homo sapiens mitogen-activated protein kinase kinase 1 (MAP2K1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu85562
Clone ID Related Accession (Same CDS sequence)	XM_017022411.1 , XM_017022411.2
Accession Version	XM_017022411.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1104bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	dual specificity mitogen-activated protein kinase kinase 1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000015.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017022411.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCCAAGA AGAAGCCGAC GCCCATCCAG CTGAACCCGG CCCCCGACGG CTCTGCAGTT 
AACGGGACCA GCTCTGCGGA GACCAACTTG GAGGCCTTGC AGAAGAAGCT GGAGGAGCTA 
GAGCTTGATG AGCAGCAGCG AAAGCGCCTT GAGGCCTTTC TTACCCAGAA GCAGAAGGTG 
GGAGAACTGA AGGATGACGA CTTTGAGAAG ATCAGTGAGC TGGGGGCTGG CAATGGCGGT 
GTGGTGTTCA AGGTCTCCCA CAAGCCTTCT GGCCTGGTCA TGGCCAGAAA GCTAATTCAT 
CTGGAGATCA AACCCGCAAT CCGGAACCAG ATCATAAGGG AGCTGCAGGT TCTGCATGAG 
TGCAACTCTC CGTACATCGT GGGCTTCTAT GGTGCGTTCT ACAGCGATGG CGAGATCAGT 
ATCTGCATGG AGCACATGGT AATAAAAGGC CTGACATATC TGAGGGAGAA GCACAAGATC 
ATGCACAGAG ATGTCAAGCC CTCCAACATC CTAGTCAACT CCCGTGGGGA GATCAAGCTC 
TGTGACTTTG GGGTCAGCGG GCAGCTCATC GACTCCATGG CCAACTCCTT CGTGGGCACA 
AGGTCCTACA TGTCGCCAGA AAGACTCCAG GGGACTCATT ACTCTGTGCA GTCAGACATC 
TGGAGCATGG GACTGTCTCT GGTAGAGATG GCGGTTGGGA GGTATCCCAT CCCTCCTCCA 
GATGCCAAGG AGCTGGAGCT GATGTTTGGG TGCCAGGTGG AAGGAGATGC GGCTGAGACC 
CCACCCAGGC CAAGGACCCC CGGGAGGCCC CTTAGCTCAT ACGGAATGGA CAGCCGACCT 
CCCATGGCAA TTTTTGAGTT GTTGGATTAC ATAGTCAACG AGCCTCCTCC AAAACTGCCC 
AGTGGAGTGT TCAGTCTGGA ATTTCAAGAT TTTGTGAATA AATGCTTAAT AAAAAACCCC 
GCAGAGAGAG CAGATTTGAA GCAACTCATG GTTCATGCTT TTATCAAGAG ATCTGATGCT 
GAGGAAGTGG ATTTTGCAGG TTGGCTCTGC TCCACCATCG GCCTTAACCA GCCCAGCACA 
CCAACCCATG CTGCTGGCGT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016877900.1
CDS	416..1519
Translation	MPKKKPTPIQLNPAPDGSAVNGTSSAETNLEALQKKLEELELDEQQRKRLEAFLTQKQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGCQVEGDAAETPPRPRTPGRPLSSYGMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIGLNQPSTPTHAAGV

Target ORF information:

RefSeq Version	XM_017022411.2
Organism	Homo sapiens(human)
Definition	Homo sapiens mitogen-activated protein kinase kinase 1 (MAP2K1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017022411.2

ORF Insert Sequence:

ATGCCCAAGA AGAAGCCGAC GCCCATCCAG CTGAACCCGG CCCCCGACGG CTCTGCAGTT 
AACGGGACCA GCTCTGCGGA GACCAACTTG GAGGCCTTGC AGAAGAAGCT GGAGGAGCTA 
GAGCTTGATG AGCAGCAGCG AAAGCGCCTT GAGGCCTTTC TTACCCAGAA GCAGAAGGTG 
GGAGAACTGA AGGATGACGA CTTTGAGAAG ATCAGTGAGC TGGGGGCTGG CAATGGCGGT 
GTGGTGTTCA AGGTCTCCCA CAAGCCTTCT GGCCTGGTCA TGGCCAGAAA GCTAATTCAT 
CTGGAGATCA AACCCGCAAT CCGGAACCAG ATCATAAGGG AGCTGCAGGT TCTGCATGAG 
TGCAACTCTC CGTACATCGT GGGCTTCTAT GGTGCGTTCT ACAGCGATGG CGAGATCAGT 
ATCTGCATGG AGCACATGGT AATAAAAGGC CTGACATATC TGAGGGAGAA GCACAAGATC 
ATGCACAGAG ATGTCAAGCC CTCCAACATC CTAGTCAACT CCCGTGGGGA GATCAAGCTC 
TGTGACTTTG GGGTCAGCGG GCAGCTCATC GACTCCATGG CCAACTCCTT CGTGGGCACA 
AGGTCCTACA TGTCGCCAGA AAGACTCCAG GGGACTCATT ACTCTGTGCA GTCAGACATC 
TGGAGCATGG GACTGTCTCT GGTAGAGATG GCGGTTGGGA GGTATCCCAT CCCTCCTCCA 
GATGCCAAGG AGCTGGAGCT GATGTTTGGG TGCCAGGTGG AAGGAGATGC GGCTGAGACC 
CCACCCAGGC CAAGGACCCC CGGGAGGCCC CTTAGCTCAT ACGGAATGGA CAGCCGACCT 
CCCATGGCAA TTTTTGAGTT GTTGGATTAC ATAGTCAACG AGCCTCCTCC AAAACTGCCC 
AGTGGAGTGT TCAGTCTGGA ATTTCAAGAT TTTGTGAATA AATGCTTAAT AAAAAACCCC 
GCAGAGAGAG CAGATTTGAA GCAACTCATG GTTCATGCTT TTATCAAGAG ATCTGATGCT 
GAGGAAGTGG ATTTTGCAGG TTGGCTCTGC TCCACCATCG GCCTTAACCA GCCCAGCACA 
CCAACCCATG CTGCTGGCGT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MAP2K1 ( XM_017022412.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016877901.1 Homo sapiens mitogen-activated protein kinase kinase 1 (MAP2K1), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu85563
Clone ID Related Accession (Same CDS sequence)	XM_017022412.1
Accession Version	XM_017022412.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1038bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	dual specificity mitogen-activated protein kinase kinase 1 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000015.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGCTGG AGAGGACCAA CTTGGAGGCC TTGCAGAAGA AGCTGGAGGA GCTAGAGCTT 
GATGAGCAGC AGCGAAAGCG CCTTGAGGCC TTTCTTACCC AGAAGCAGAA GGTGGGAGAA 
CTGAAGGATG ACGACTTTGA GAAGATCAGT GAGCTGGGGG CTGGCAATGG CGGTGTGGTG 
TTCAAGGTCT CCCACAAGCC TTCTGGCCTG GTCATGGCCA GAAAGCTAAT TCATCTGGAG 
ATCAAACCCG CAATCCGGAA CCAGATCATA AGGGAGCTGC AGGTTCTGCA TGAGTGCAAC 
TCTCCGTACA TCGTGGGCTT CTATGGTGCG TTCTACAGCG ATGGCGAGAT CAGTATCTGC 
ATGGAGCACA TGGTAATAAA AGGCCTGACA TATCTGAGGG AGAAGCACAA GATCATGCAC 
AGAGATGTCA AGCCCTCCAA CATCCTAGTC AACTCCCGTG GGGAGATCAA GCTCTGTGAC 
TTTGGGGTCA GCGGGCAGCT CATCGACTCC ATGGCCAACT CCTTCGTGGG CACAAGGTCC 
TACATGTCGC CAGAAAGACT CCAGGGGACT CATTACTCTG TGCAGTCAGA CATCTGGAGC 
ATGGGACTGT CTCTGGTAGA GATGGCGGTT GGGAGGTATC CCATCCCTCC TCCAGATGCC 
AAGGAGCTGG AGCTGATGTT TGGGTGCCAG GTGGAAGGAG ATGCGGCTGA GACCCCACCC 
AGGCCAAGGA CCCCCGGGAG GCCCCTTAGC TCATACGGAA TGGACAGCCG ACCTCCCATG 
GCAATTTTTG AGTTGTTGGA TTACATAGTC AACGAGCCTC CTCCAAAACT GCCCAGTGGA 
GTGTTCAGTC TGGAATTTCA AGATTTTGTG AATAAATGCT TAATAAAAAA CCCCGCAGAG 
AGAGCAGATT TGAAGCAACT CATGGTTCAT GCTTTTATCA AGAGATCTGA TGCTGAGGAA 
GTGGATTTTG CAGGTTGGCT CTGCTCCACC ATCGGCCTTA ACCAGCCCAG CACACCAACC 
CATGCTGCTG GCGTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016877901.1
CDS	79..1116
Translation	MKLERTNLEALQKKLEELELDEQQRKRLEAFLTQKQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGCQVEGDAAETPPRPRTPGRPLSSYGMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIGLNQPSTPTHAAGV

Target ORF information:

RefSeq Version	XM_017022412.1
Organism	Homo sapiens(human)
Definition	Homo sapiens mitogen-activated protein kinase kinase 1 (MAP2K1), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017022412.1

ORF Insert Sequence:

ATGAAGCTGG AGAGGACCAA CTTGGAGGCC TTGCAGAAGA AGCTGGAGGA GCTAGAGCTT 
GATGAGCAGC AGCGAAAGCG CCTTGAGGCC TTTCTTACCC AGAAGCAGAA GGTGGGAGAA 
CTGAAGGATG ACGACTTTGA GAAGATCAGT GAGCTGGGGG CTGGCAATGG CGGTGTGGTG 
TTCAAGGTCT CCCACAAGCC TTCTGGCCTG GTCATGGCCA GAAAGCTAAT TCATCTGGAG 
ATCAAACCCG CAATCCGGAA CCAGATCATA AGGGAGCTGC AGGTTCTGCA TGAGTGCAAC 
TCTCCGTACA TCGTGGGCTT CTATGGTGCG TTCTACAGCG ATGGCGAGAT CAGTATCTGC 
ATGGAGCACA TGGTAATAAA AGGCCTGACA TATCTGAGGG AGAAGCACAA GATCATGCAC 
AGAGATGTCA AGCCCTCCAA CATCCTAGTC AACTCCCGTG GGGAGATCAA GCTCTGTGAC 
TTTGGGGTCA GCGGGCAGCT CATCGACTCC ATGGCCAACT CCTTCGTGGG CACAAGGTCC 
TACATGTCGC CAGAAAGACT CCAGGGGACT CATTACTCTG TGCAGTCAGA CATCTGGAGC 
ATGGGACTGT CTCTGGTAGA GATGGCGGTT GGGAGGTATC CCATCCCTCC TCCAGATGCC 
AAGGAGCTGG AGCTGATGTT TGGGTGCCAG GTGGAAGGAG ATGCGGCTGA GACCCCACCC 
AGGCCAAGGA CCCCCGGGAG GCCCCTTAGC TCATACGGAA TGGACAGCCG ACCTCCCATG 
GCAATTTTTG AGTTGTTGGA TTACATAGTC AACGAGCCTC CTCCAAAACT GCCCAGTGGA 
GTGTTCAGTC TGGAATTTCA AGATTTTGTG AATAAATGCT TAATAAAAAA CCCCGCAGAG 
AGAGCAGATT TGAAGCAACT CATGGTTCAT GCTTTTATCA AGAGATCTGA TGCTGAGGAA 
GTGGATTTTG CAGGTTGGCT CTGCTCCACC ATCGGCCTTA ACCAGCCCAG CACACCAACC 
CATGCTGCTG GCGTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MAP2K1 ( XM_017022413.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016877902.1 Homo sapiens mitogen-activated protein kinase kinase 1 (MAP2K1), transcript variant X4, mRNA.

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CloneID	OHu85564
Clone ID Related Accession (Same CDS sequence)	XM_017022413.1
Accession Version	XM_017022413.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 654bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	dual specificity mitogen-activated protein kinase kinase 1 isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000015.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTACCTG TGCACCAGCA ATTCCTGAGC AAGCAGCACA ATGTCAAGCC CTCCAACATC 
CTAGTCAACT CCCGTGGGGA GATCAAGCTC TGTGACTTTG GGGTCAGCGG GCAGCTCATC 
GACTCCATGG CCAACTCCTT CGTGGGCACA AGGTCCTACA TGTCGCCAGA AAGACTCCAG 
GGGACTCATT ACTCTGTGCA GTCAGACATC TGGAGCATGG GACTGTCTCT GGTAGAGATG 
GCGGTTGGGA GGTATCCCAT CCCTCCTCCA GATGCCAAGG AGCTGGAGCT GATGTTTGGG 
TGCCAGGTGG AAGGAGATGC GGCTGAGACC CCACCCAGGC CAAGGACCCC CGGGAGGCCC 
CTTAGCTCAT ACGGAATGGA CAGCCGACCT CCCATGGCAA TTTTTGAGTT GTTGGATTAC 
ATAGTCAACG AGCCTCCTCC AAAACTGCCC AGTGGAGTGT TCAGTCTGGA ATTTCAAGAT 
TTTGTGAATA AATGCTTAAT AAAAAACCCC GCAGAGAGAG CAGATTTGAA GCAACTCATG 
GTTCATGCTT TTATCAAGAG ATCTGATGCT GAGGAAGTGG ATTTTGCAGG TTGGCTCTGC 
TCCACCATCG GCCTTAACCA GCCCAGCACA CCAACCCATG CTGCTGGCGT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016877902.1
CDS	1072..1725
Translation	MVPVHQQFLSKQHNVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGCQVEGDAAETPPRPRTPGRPLSSYGMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIGLNQPSTPTHAAGV

Target ORF information:

RefSeq Version	XM_017022413.1
Organism	Homo sapiens(human)
Definition	Homo sapiens mitogen-activated protein kinase kinase 1 (MAP2K1), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017022413.1

ORF Insert Sequence:

ATGGTACCTG TGCACCAGCA ATTCCTGAGC AAGCAGCACA ATGTCAAGCC CTCCAACATC 
CTAGTCAACT CCCGTGGGGA GATCAAGCTC TGTGACTTTG GGGTCAGCGG GCAGCTCATC 
GACTCCATGG CCAACTCCTT CGTGGGCACA AGGTCCTACA TGTCGCCAGA AAGACTCCAG 
GGGACTCATT ACTCTGTGCA GTCAGACATC TGGAGCATGG GACTGTCTCT GGTAGAGATG 
GCGGTTGGGA GGTATCCCAT CCCTCCTCCA GATGCCAAGG AGCTGGAGCT GATGTTTGGG 
TGCCAGGTGG AAGGAGATGC GGCTGAGACC CCACCCAGGC CAAGGACCCC CGGGAGGCCC 
CTTAGCTCAT ACGGAATGGA CAGCCGACCT CCCATGGCAA TTTTTGAGTT GTTGGATTAC 
ATAGTCAACG AGCCTCCTCC AAAACTGCCC AGTGGAGTGT TCAGTCTGGA ATTTCAAGAT 
TTTGTGAATA AATGCTTAAT AAAAAACCCC GCAGAGAGAG CAGATTTGAA GCAACTCATG 
GTTCATGCTT TTATCAAGAG ATCTGATGCT GAGGAAGTGG ATTTTGCAGG TTGGCTCTGC 
TCCACCATCG GCCTTAACCA GCCCAGCACA CCAACCCATG CTGCTGGCGT CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

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MAP2K1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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