BARX1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	BARX1
Entrez Gene ID	56033
Full Name	BARX homeobox 1
General protein information	Preferred Names BARX homeobox 1 Names homeobox protein BarH-like 1 BarH-like homeobox 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 9 Map Location: 9q22.32
Summary	This gene encodes a member of the Bar subclass of homeobox transcription factors. Studies of the mouse and chick homolog suggest the encoded protein may play a role in developing teeth and craniofacial mesenchyme of neural crest origin. The protein may also be associated with differentiation of stomach epithelia. [provided by RefSeq, Jul 2008].
Disorder MIM:	603260

mRNA and Protein(s)

mRNA	Protein	Name
NM_021570.3	NP_067545.3	homeobox protein BarH-like 1
NM_021570.4	NP_067545.3	homeobox protein BarH-like 1

Pathways from BioSystems

Homologies

Xenopus tropicalis (tropical clawed frog)	LOC100491751	XP_004914882.1
Pan troglodytes (chimpanzee)	BARX1	XP_001151327.2
Bos taurus (cattle)	BARX1	XP_003586472.1
Mus musculus (house mouse)	Barx1	NP_031552.2
Rattus norvegicus (Norway rat)	Barx1	NP_001102350.1
Homo sapiens (human)	BARX1	NP_067545.3
Gallus gallus (chicken)	BARX1	NP_989524.1
Canis lupus familiaris (dog)	BARX1	XP_853092.1
Danio rerio (zebrafish)	barx1	NP_001020120.1

Gene Ontology
Bibliography

Related articles in PubMed

Supportive evidence for FOXP1, BARX1, and FOXF1 as genetic risk loci for the development of esophageal adenocarcinoma.
Becker J, May A, Gerges C, Anders M, Veits L, Weise K, Czamara D, Lyros O, Manner H, Terheggen G, Venerito M, Noder T, Mayershofer R, Hofer JH, Karch HW, Ahlbrand CJ, Arras M, Hofer S, Mangold E, Heilmann-Heimbach S, Heinrichs SK, Hess T, Kiesslich R, Izbicki JR, H?lscher AH, Bollschweiler E, Malfertheiner P, Lang H, Moehler M, Lorenz D, M?ller-Myhsok B, Ott K, Schmidt T, Whiteman DC, Vaughan TL, N?then MM, Hackelsberger A, Schumacher B, Pech O, Vashist Y, Vieth M, Weism?ller J, Neuhaus H, R?sch T, Ell C, Gockel I, Schumacher J
Cancer medicine4(11)1700-4(2015 Nov)

A genome-wide association study identifies new susceptibility loci for esophageal adenocarcinoma and Barrett's esophagus.
Levine DM, Ek WE, Zhang R, Liu X, Onstad L, Sather C, Lao-Sirieix P, Gammon MD, Corley DA, Shaheen NJ, Bird NC, Hardie LJ, Murray LJ, Reid BJ, Chow WH, Risch HA, Nyr?n O, Ye W, Liu G, Romero Y, Bernstein L, Wu AH, Casson AG, Chanock SJ, Harrington P, Caldas I, Debiram-Beecham I, Caldas C, Hayward NK, Pharoah PD, Fitzgerald RC, Macgregor S, Whiteman DC, Vaughan TL
Nature genetics45(12)1487-93(2013 Dec)

Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia.
Jugessur A, Shi M, Gjessing HK, Lie RT, Wilcox AJ, Weinberg CR, Christensen K, Boyles AL, Daack-Hirsch S, Nguyen TT, Christiansen L, Lidral AC, Murray JC
PloS one5(7)e11493(2010 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

we provide supportive evidence that genetic variants at FOXP1, BARX1, and FOXF1 confer risk for the development of EAC.
Title: Supportive evidence for FOXP1, BARX1, and FOXF1 as genetic risk loci for the development of esophageal adenocarcinoma.

Observational study of gene-disease association. (HuGE Navigator)
Title: Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia.

Observational study of gene-disease association. (HuGE Navigator)
Title: Candidate gene/loci studies in cleft lip/palate and dental anomalies finds novel susceptibility genes for clefts.

Regional expression of barx1 was observed in epithelium before mixed dentition, while during mixed dentition gene appeared in hyaline cartilage. Expression of barx1 appears in cleft lip palate affected structures mainly in mixed dentition.
Title: Barx1, growth factors and apoptosis in facial tissue of children with clefts.

PITX2, BARX1, and FOXC1 mutations were absent in De Hauwere syndrome and suggest that De Hauwere syndrome is caused by a different gene.
Title: Absence of PITX2, BARX1, and FOXC1 mutations in De Hauwere syndrome (Axenfeld-Rieger anomaly, hydrocephaly, hearing loss): a 25-year follow up.

The following BARX1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the BARX1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu15603	NM_021570.4 Latest version!	Homo sapiens BARX homeobox 1 (BARX1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu15603	NM_021570.3	Homo sapiens BARX homeobox 1 (BARX1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

BARX1 ( NM_021570.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_067545.3 Homo sapiens BARX homeobox 1 (BARX1), mRNA.

Price & Availability↑

CloneID	OHu15603
Clone ID Related Accession (Same CDS sequence)	NM_021570.3 , NM_021570.4
Accession Version	NM_021570.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 765bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	homeobox protein BarH-like 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC064363.1 and BC009458.1. On Jul 24, 2007 this sequence version replaced NM_021570.2. ##Evidence-Data-START## Transcript exon combination :: BC064363.1, AL555424.3 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968540, SAMEA1968832 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCAGCGGC CGGGGGAGCC GGGCGCCGCG CGCTTCGGCC CGCCCGAGGG CTGCGCGGAC 
CACCGGCCGC ACCGCTATCG CAGCTTCATG ATTGAGGAGA TCCTCACGGA GCCACCCGGG 
CCCAAGGGCG CCGCGCCCGC AGCCGCCGCT GCCGCGGCGG GCGAGCTGCT GAAGTTCGGC 
GTGCAGGCGC TGCTGGCGGC GCGGCCCTTC CACAGCCACC TGGCCGTGCT GAAGGCCGAG 
CAGGCGGCGG TGTTCAAGTT CCCACTGGCG CCGCTGGGCT GTTCAGGGCT GAGCTCTGCG 
TTGCTGGCGG CAGGGCCCGG GCTGCCCGGC GCCGCGGGTG CGCCACACCT GCCGCTCGAG 
TTGCAGCTCC GCGGGAAGCT GGAGGCGGCA GGCCCTGGGG AGCCAGGCAC CAAAGCCAAG 
AAGGGGCGTC GGAGCCGCAC TGTGTTCACC GAGCTGCAGC TGATGGGCCT GGAGAAACGC 
TTCGAGAAGC AGAAGTACCT TTCCACGCCG GACAGAATAG ATCTTGCTGA GTCCCTGGGC 
CTGAGCCAGT TGCAGGTGAA GACGTGGTAC CAGAATCGGA GGATGAAGTG GAAGAAAATA 
GTGCTGCAGG GCGGCGGCCT GGAGTCTCCC ACCAAGCCCA AGGGGCGGCC CAAGAAGAAC 
TCAATTCCAA CGAGCGAGCA GCTTACTGAG CAGGAGCGCG CCAAGGATGC AGAGAAACCG 
GCGGAGGTGC CGGGCGAGCC CAGCGACAGG AGCCGCGAGG ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_067545.3
CDS	181..945
Translation	MQRPGEPGAARFGPPEGCADHRPHRYRSFMIEEILTEPPGPKGAAPAAAAAAAGELLKFGVQALLAARPFHSHLAVLKAEQAAVFKFPLAPLGCSGLSSALLAAGPGLPGAAGAPHLPLELQLRGKLEAAGPGEPGTKAKKGRRSRTVFTELQLMGLEKRFEKQKYLSTPDRIDLAESLGLSQLQVKTWYQNRRMKWKKIVLQGGGLESPTKPKGRPKKNSIPTSEQLTEQERAKDAEKPAEVPGEPSDRSRED

Target ORF information:

RefSeq Version	NM_021570.3
Organism	Homo sapiens(human)
Definition	Homo sapiens BARX homeobox 1 (BARX1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021570.3

ORF Insert Sequence:

ATGCAGCGGC CGGGGGAGCC GGGCGCCGCG CGCTTCGGCC CGCCCGAGGG CTGCGCGGAC 
CACCGGCCGC ACCGCTATCG CAGCTTCATG ATTGAGGAGA TCCTCACGGA GCCACCCGGG 
CCCAAGGGCG CCGCGCCCGC AGCCGCCGCT GCCGCGGCGG GCGAGCTGCT GAAGTTCGGC 
GTGCAGGCGC TGCTGGCGGC GCGGCCCTTC CACAGCCACC TGGCCGTGCT GAAGGCCGAG 
CAGGCGGCGG TGTTCAAGTT CCCACTGGCG CCGCTGGGCT GTTCAGGGCT GAGCTCTGCG 
TTGCTGGCGG CAGGGCCCGG GCTGCCCGGC GCCGCGGGTG CGCCACACCT GCCGCTCGAG 
TTGCAGCTCC GCGGGAAGCT GGAGGCGGCA GGCCCTGGGG AGCCAGGCAC CAAAGCCAAG 
AAGGGGCGTC GGAGCCGCAC TGTGTTCACC GAGCTGCAGC TGATGGGCCT GGAGAAACGC 
TTCGAGAAGC AGAAGTACCT TTCCACGCCG GACAGAATAG ATCTTGCTGA GTCCCTGGGC 
CTGAGCCAGT TGCAGGTGAA GACGTGGTAC CAGAATCGGA GGATGAAGTG GAAGAAAATA 
GTGCTGCAGG GCGGCGGCCT GGAGTCTCCC ACCAAGCCCA AGGGGCGGCC CAAGAAGAAC 
TCAATTCCAA CGAGCGAGCA GCTTACTGAG CAGGAGCGCG CCAAGGATGC AGAGAAACCG 
GCGGAGGTGC CGGGCGAGCC CAGCGACAGG AGCCGCGAGG ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BARX1 ( NM_021570.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_067545.3 Homo sapiens BARX homeobox 1 (BARX1), mRNA.

Price & Availability↑

CloneID	OHu15603
Clone ID Related Accession (Same CDS sequence)	NM_021570.3 , NM_021570.4
Accession Version	NM_021570.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 765bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	homeobox protein BarH-like 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL357073.19, BC064363.1 and BC009458.1. On Nov 23, 2018 this sequence version replaced NM_021570.3. ##Evidence-Data-START## Transcript exon combination :: BC064363.1, AL555424.3 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968540, SAMEA1968832 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000253968.11/ ENSP00000253968.5 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCAGCGGC CGGGGGAGCC GGGCGCCGCG CGCTTCGGCC CGCCCGAGGG CTGCGCGGAC 
CACCGGCCGC ACCGCTATCG CAGCTTCATG ATTGAGGAGA TCCTCACGGA GCCACCCGGG 
CCCAAGGGCG CCGCGCCCGC AGCCGCCGCT GCCGCGGCGG GCGAGCTGCT GAAGTTCGGC 
GTGCAGGCGC TGCTGGCGGC GCGGCCCTTC CACAGCCACC TGGCCGTGCT GAAGGCCGAG 
CAGGCGGCGG TGTTCAAGTT CCCACTGGCG CCGCTGGGCT GTTCAGGGCT GAGCTCTGCG 
TTGCTGGCGG CAGGGCCCGG GCTGCCCGGC GCCGCGGGTG CGCCACACCT GCCGCTCGAG 
TTGCAGCTCC GCGGGAAGCT GGAGGCGGCA GGCCCTGGGG AGCCAGGCAC CAAAGCCAAG 
AAGGGGCGTC GGAGCCGCAC TGTGTTCACC GAGCTGCAGC TGATGGGCCT GGAGAAACGC 
TTCGAGAAGC AGAAGTACCT TTCCACGCCG GACAGAATAG ATCTTGCTGA GTCCCTGGGC 
CTGAGCCAGT TGCAGGTGAA GACGTGGTAC CAGAATCGGA GGATGAAGTG GAAGAAAATA 
GTGCTGCAGG GCGGCGGCCT GGAGTCTCCC ACCAAGCCCA AGGGGCGGCC CAAGAAGAAC 
TCAATTCCAA CGAGCGAGCA GCTTACTGAG CAGGAGCGCG CCAAGGATGC AGAGAAACCG 
GCGGAGGTGC CGGGCGAGCC CAGCGACAGG AGCCGCGAGG ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_067545.3
CDS	210..974
Translation	MQRPGEPGAARFGPPEGCADHRPHRYRSFMIEEILTEPPGPKGAAPAAAAAAAGELLKFGVQALLAARPFHSHLAVLKAEQAAVFKFPLAPLGCSGLSSALLAAGPGLPGAAGAPHLPLELQLRGKLEAAGPGEPGTKAKKGRRSRTVFTELQLMGLEKRFEKQKYLSTPDRIDLAESLGLSQLQVKTWYQNRRMKWKKIVLQGGGLESPTKPKGRPKKNSIPTSEQLTEQERAKDAEKPAEVPGEPSDRSRED

Target ORF information:

RefSeq Version	NM_021570.4
Organism	Homo sapiens(human)
Definition	Homo sapiens BARX homeobox 1 (BARX1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021570.4

ORF Insert Sequence:

ATGCAGCGGC CGGGGGAGCC GGGCGCCGCG CGCTTCGGCC CGCCCGAGGG CTGCGCGGAC 
CACCGGCCGC ACCGCTATCG CAGCTTCATG ATTGAGGAGA TCCTCACGGA GCCACCCGGG 
CCCAAGGGCG CCGCGCCCGC AGCCGCCGCT GCCGCGGCGG GCGAGCTGCT GAAGTTCGGC 
GTGCAGGCGC TGCTGGCGGC GCGGCCCTTC CACAGCCACC TGGCCGTGCT GAAGGCCGAG 
CAGGCGGCGG TGTTCAAGTT CCCACTGGCG CCGCTGGGCT GTTCAGGGCT GAGCTCTGCG 
TTGCTGGCGG CAGGGCCCGG GCTGCCCGGC GCCGCGGGTG CGCCACACCT GCCGCTCGAG 
TTGCAGCTCC GCGGGAAGCT GGAGGCGGCA GGCCCTGGGG AGCCAGGCAC CAAAGCCAAG 
AAGGGGCGTC GGAGCCGCAC TGTGTTCACC GAGCTGCAGC TGATGGGCCT GGAGAAACGC 
TTCGAGAAGC AGAAGTACCT TTCCACGCCG GACAGAATAG ATCTTGCTGA GTCCCTGGGC 
CTGAGCCAGT TGCAGGTGAA GACGTGGTAC CAGAATCGGA GGATGAAGTG GAAGAAAATA 
GTGCTGCAGG GCGGCGGCCT GGAGTCTCCC ACCAAGCCCA AGGGGCGGCC CAAGAAGAAC 
TCAATTCCAA CGAGCGAGCA GCTTACTGAG CAGGAGCGCG CCAAGGATGC AGAGAAACCG 
GCGGAGGTGC CGGGCGAGCC CAGCGACAGG AGCCGCGAGG ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Supportive evidence for FOXP1, BARX1, and FOXF1 as genetic risk loci for the development of esophageal adenocarcinoma.
Cancer medicine4(11)1700-4(2015 Nov)
Becker J,May A,Gerges C,Anders M,Veits L,Weise K,Czamara D,Lyros O,Manner H,Terheggen G,Venerito M,Noder T,Mayershofer R,Hofer JH,Karch HW,Ahlbrand CJ,Arras M,Hofer S,Mangold E,Heilmann-Heimbach S,Heinrichs SK,Hess T,Kiesslich R,Izbicki JR,H?lscher AH,Bollschweiler E,Malfertheiner P,Lang H,Moehler M,Lorenz D,M?ller-Myhsok B,Ott K,Schmidt T,Whiteman DC,Vaughan TL,N?then MM,Hackelsberger A,Schumacher B,Pech O,Vashist Y,Vieth M,Weism?ller J,Neuhaus H,R?sch T,Ell C,Gockel I,Schumacher J

A genome-wide association study identifies new susceptibility loci for esophageal adenocarcinoma and Barrett's esophagus.
Nature genetics45(12)1487-93(2013 Dec)
Levine DM,Ek WE,Zhang R,Liu X,Onstad L,Sather C,Lao-Sirieix P,Gammon MD,Corley DA,Shaheen NJ,Bird NC,Hardie LJ,Murray LJ,Reid BJ,Chow WH,Risch HA,Nyr?n O,Ye W,Liu G,Romero Y,Bernstein L,Wu AH,Casson AG,Chanock SJ,Harrington P,Caldas I,Debiram-Beecham I,Caldas C,Hayward NK,Pharoah PD,Fitzgerald RC,Macgregor S,Whiteman DC,Vaughan TL

Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia.
PloS one5(7)e11493(2010 Jul)
Jugessur A,Shi M,Gjessing HK,Lie RT,Wilcox AJ,Weinberg CR,Christensen K,Boyles AL,Daack-Hirsch S,Nguyen TT,Christiansen L,Lidral AC,Murray JC

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BARX1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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