BAIAP2L1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	BAIAP2L1
Entrez Gene ID	55971
Full Name	BAI1 associated protein 2 like 1
Synonyms	IRTKS
General protein information	Preferred Names BAI1 associated protein 2 like 1 Names brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 BAI1-associated protein 2-like protein 1 insulin receptor tyrosine kinase substrate
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 7 Map Location: 7q21.3-q22.1
Summary	This gene encodes a member of the IMD (IRSp53/MIM homology domain) family. Members of this family can be subdivided in two groups, the IRSp53-like and MIM-like, based on the presence or absence of the SH3 (Src homology 3) domain. The protein encoded by this gene contains a conserved IMD, also known as F-actin bundling domain, at the N-terminus, and a canonical SH3 domain near the C-terminus, so it belongs to the IRSp53-like group. This protein is the substrate for insulin receptor tyrosine kinase and binds to the small GTPase Rac. It is involved in signal transduction pathways that link deformation of the plasma membrane and remodeling of the actin cytoskeleton. It also promotes actin assembly and membrane protrusions when overexpressed in mammalian cells, and is essential to the formation of a potent actin assembly complex during EHEC (Enterohemorrhagic Escherichia coli) pedestal formation. [provided by RefSeq, Oct 2009].
Disorder MIM:	611877

mRNA and Protein(s)

mRNA	Protein	Name
NM_018842.4	NP_061330.2	brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1
NM_018842.5	NP_061330.2	brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	BAIAP2L1	XP_536876.4
Pan troglodytes (chimpanzee)	BAIAP2L1	XP_519222.3
Xenopus tropicalis (tropical clawed frog)	baiap2l1	NP_001093697.1
Mus musculus (house mouse)	Baiap2l1	NP_080109.1
Rattus norvegicus (Norway rat)	Baiap2l1	NP_001029312.1
Danio rerio (zebrafish)	baiap2l1b	NP_001017830.1
Homo sapiens (human)	BAIAP2L1	NP_061330.2
	BAIAP2L1	XP_001110709.2
Bos taurus (cattle)	BAIAP2L1	XP_003587892.1
Gallus gallus (chicken)	BAIAP2L1	NP_001264458.1
Danio rerio (zebrafish)	baiap2l1a	NP_944604.1

Gene Ontology
Bibliography

Related articles in PubMed

The SH3 domain distinguishes the role of I-BAR proteins IRTKS and MIM in chemotactic response to serum.
Li L, Liu H, Baxter SS, Gu N, Ji M, Zhan X
Biochemical and biophysical research communications479(4)787-792(2016 Oct)

The Rho GTPase Rif signals through IRTKS, Eps8 and WAVE2 to generate dorsal membrane ruffles and filopodia.
Sudhaharan T, Sem KP, Liew HF, Yu YH, Goh WI, Chou AM, Ahmed S
Journal of cell science129(14)2829-40(2016 07)

Mechanism of Oncogenic Signal Activation by the Novel Fusion Kinase FGFR3-BAIAP2L1.
Nakanishi Y, Akiyama N, Tsukaguchi T, Fujii T, Satoh Y, Ishii N, Aoki M
Molecular cancer therapeutics14(3)704-12(2015 Mar)

BAI1-Associated Protein 2-Like 1 (BAIAP2L1) Is a Potential Biomarker in Ovarian Cancer.
Chao A, Tsai CL, Jung SM, Chuang WC, Kao C, Hsu A, Chen SH, Lin CY, Lee YC, Lee YS, Wang TH, Wang HS, Lai CH
PloS one10(7)e0133081(2015)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

IRTKS promoted serum-induced cell migration along with enhanced phosphorylation of mitogen activated kinases Erk1/2 and p38, and activation of small GTPases Rac1 and Cdc42. In addition, cells overexpressing IRTKS exhibited an increased polarity characterized by elongated cytoplasm and extensive lamellipodia at leading edges.
Title: The SH3 domain distinguishes the role of I-BAR proteins IRTKS and MIM in chemotactic response to serum.

Rho family GTPases use the I-BAR proteins, IRSp53 (also known as BAIAP2), IRTKS and Pinkbar, as a central mechanism to modulate cell morphology.
Title: The Rho GTPase Rif signals through IRTKS, Eps8 and WAVE2 to generate dorsal membrane ruffles and filopodia.

Lacking the Bin-Amphiphysin-Rvs (BAR) dimerization domain of BAIAP2L1.
Title: Mechanism of Oncogenic Signal Activation by the Novel Fusion Kinase FGFR3-BAIAP2L1.

Upregulation of BAIAP2L1 is associated with ovarian cancer.
Title: BAI1-Associated Protein 2-Like 1 (BAIAP2L1) Is a Potential Biomarker in Ovarian Cancer.

IRTKS can interact with epidermal growth factor receptor (EGFR), results in the phosphorylation of extracellular signal-regulated kinase
Title: Insulin receptor tyrosine kinase substrate activates EGFR/ERK signalling pathway and promotes cell proliferation of hepatocellular carcinoma.

The following BAIAP2L1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the BAIAP2L1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu19617	NM_018842.5 Latest version!	Homo sapiens BAR/IMD domain containing adaptor protein 2 like 1 (BAIAP2L1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
View Old Accession Versions >>
OHu19617	NM_018842.4	Homo sapiens BAI1 associated protein 2 like 1 (BAIAP2L1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

BAIAP2L1 ( NM_018842.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_061330.2 Homo sapiens BAI1 associated protein 2 like 1 (BAIAP2L1), mRNA.

Price & Availability↑

CloneID	OHu19617
Clone ID Related Accession (Same CDS sequence)	NM_018842.4 , NM_018842.5
Accession Version	NM_018842.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1536bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-11-27
Organism	Homo sapiens(human)
Product	brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI560834.1, DA442866.1, BC013888.2, AK074419.1 and BM977002.1. This sequence is a reference standard in the RefSeqGene project. On Apr 25, 2009 this sequence version replaced NM_018842.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.72776.1, AF119666.2 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCCCGGG GGCCCGAGGA GGTGAACCGG CTCACGGAGA GCACCTACCG GAATGTTATG 
GAACAGTTCA ATCCTGGGCT GCGAAATTTA ATAAACCTGG GGAAAAATTA TGAGAAAGCT 
GTAAACGCTA TGATCCTGGC AGGAAAAGCC TACTACGATG GAGTGGCCAA GATCGGTGAG 
ATTGCCACTG GGTCCCCCGT GTCAACTGAA CTGGGACATG TCCTCATAGA GATTTCAAGT 
ACCCACAAGA AACTCAACGA GAGTCTTGAT GAAAATTTTA AAAAATTCCA CAAAGAGATT 
ATCCATGAGC TGGAGAAGAA GATAGAACTT GACGTGAAAT ATATGAACGC AACTCTAAAA 
AGATACCAAA CAGAACACAA GAATAAATTA GAGTCTTTGG AGAAATCCCA AGCTGAGTTG 
AAGAAGATCA GAAGGAAAAG CCAAGGAAGC CGAAACGCAC TCAAATATGA ACACAAAGAA 
ATTGAGTATG TGGAGACCGT TACTTCTCGT CAGAGTGAAA TCCAGAAATT CATTGCAGAT 
GGTTGCAAAG AGGCTCTGCT TGAAGAGAAG AGGCGCTTCT GCTTTCTGGT TGATAAGCAC 
TGTGGCTTTG CAAACCACAT ACATTATTAT CACTTACAGT CTGCAGAACT ACTGAATTCC 
AAGCTGCCTC GGTGGCAGGA GACCTGTGTT GATGCCATCA AAGTGCCAGA GAAAATCATG 
AATATGATCG AAGAAATAAA GACCCCAGCC TCTACCCCCG TGTCTGGAAC TCCTCAGGCT 
TCACCCATGA TCGAGAGAAG CAATGTGGTT AGGAAAGATT ACGACACCCT TTCTAAATGC 
TCACCAAAGA TGCCCCCCGC TCCTTCAGGC AGAGCATATA CCAGTCCCTT GATCGATATG 
TTTAATAACC CAGCCACGGC TGCCCCGAAT TCACAAAGGG TAAATAATTC AACAGGTACT 
TCCGAAGATC CCAGTTTACA GCGATCAGTT TCGGTTGCAA CGGGACTGAA CATGATGAAG 
AAGCAGAAAG TGAAGACCAT CTTCCCGCAC ACTGCGGGCT CCAACAAGAC CTTACTCAGC 
TTTGCACAGG GAGATGTCAT CACGCTGCTC ATCCCCGAGG AGAAGGATGG CTGGCTCTAT 
GGAGAACACG ACGTGTCCAA GGCGAGGGGT TGGTTCCCGT CGTCGTACAC GAAGTTGCTG 
GAAGAAAATG AGACAGAAGC AGTGACCGTG CCCACGCCAA GCCCCACACC AGTGAGAAGC 
ATCAGCACCG TGAACTTGTC TGAGAATAGC AGTGTTGTCA TCCCCCCACC CGACTACTTG 
GAATGCTTGT CCATGGGGGC AGCTGCCGAC AGGAGAGCAG ATTCGGCCAG GACGACATCC 
ACCTTTAAGG CCCCAGCGTC CAAGCCCGAG ACCGCGGCTC CTAACGATGC CAACGGGACT 
GCAAAGCCGC CTTTTCTCAG CGGAGAAAAC CCCTTTGCCA CTGTGAAACT CCGCCCGACT 
GTGACGAATG ATCGCTCGGC ACCCATCATT CGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_061330.2
CDS	264..1799
Translation	MSRGPEEVNRLTESTYRNVMEQFNPGLRNLINLGKNYEKAVNAMILAGKAYYDGVAKIGEIATGSPVSTELGHVLIEISSTHKKLNESLDENFKKFHKEIIHELEKKIELDVKYMNATLKRYQTEHKNKLESLEKSQAELKKIRRKSQGSRNALKYEHKEIEYVETVTSRQSEIQKFIADGCKEALLEEKRRFCFLVDKHCGFANHIHYYHLQSAELLNSKLPRWQETCVDAIKVPEKIMNMIEEIKTPASTPVSGTPQASPMIERSNVVRKDYDTLSKCSPKMPPAPSGRAYTSPLIDMFNNPATAAPNSQRVNNSTGTSEDPSLQRSVSVATGLNMMKKQKVKTIFPHTAGSNKTLLSFAQGDVITLLIPEEKDGWLYGEHDVSKARGWFPSSYTKLLEENETEAVTVPTPSPTPVRSISTVNLSENSSVVIPPPDYLECLSMGAAADRRADSARTTSTFKAPASKPETAAPNDANGTAKPPFLSGENPFATVKLRPTVTNDRSAPIIR

Target ORF information:

RefSeq Version	NM_018842.4
Organism	Homo sapiens(human)
Definition	Homo sapiens BAI1 associated protein 2 like 1 (BAIAP2L1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018842.4

ORF Insert Sequence:

ATGTCCCGGG GGCCCGAGGA GGTGAACCGG CTCACGGAGA GCACCTACCG GAATGTTATG 
GAACAGTTCA ATCCTGGGCT GCGAAATTTA ATAAACCTGG GGAAAAATTA TGAGAAAGCT 
GTAAACGCTA TGATCCTGGC AGGAAAAGCC TACTACGATG GAGTGGCCAA GATCGGTGAG 
ATTGCCACTG GGTCCCCCGT GTCAACTGAA CTGGGACATG TCCTCATAGA GATTTCAAGT 
ACCCACAAGA AACTCAACGA GAGTCTTGAT GAAAATTTTA AAAAATTCCA CAAAGAGATT 
ATCCATGAGC TGGAGAAGAA GATAGAACTT GACGTGAAAT ATATGAACGC AACTCTAAAA 
AGATACCAAA CAGAACACAA GAATAAATTA GAGTCTTTGG AGAAATCCCA AGCTGAGTTG 
AAGAAGATCA GAAGGAAAAG CCAAGGAAGC CGAAACGCAC TCAAATATGA ACACAAAGAA 
ATTGAGTATG TGGAGACCGT TACTTCTCGT CAGAGTGAAA TCCAGAAATT CATTGCAGAT 
GGTTGCAAAG AGGCTCTGCT TGAAGAGAAG AGGCGCTTCT GCTTTCTGGT TGATAAGCAC 
TGTGGCTTTG CAAACCACAT ACATTATTAT CACTTACAGT CTGCAGAACT ACTGAATTCC 
AAGCTGCCTC GGTGGCAGGA GACCTGTGTT GATGCCATCA AAGTGCCAGA GAAAATCATG 
AATATGATCG AAGAAATAAA GACCCCAGCC TCTACCCCCG TGTCTGGAAC TCCTCAGGCT 
TCACCCATGA TCGAGAGAAG CAATGTGGTT AGGAAAGATT ACGACACCCT TTCTAAATGC 
TCACCAAAGA TGCCCCCCGC TCCTTCAGGC AGAGCATATA CCAGTCCCTT GATCGATATG 
TTTAATAACC CAGCCACGGC TGCCCCGAAT TCACAAAGGG TAAATAATTC AACAGGTACT 
TCCGAAGATC CCAGTTTACA GCGATCAGTT TCGGTTGCAA CGGGACTGAA CATGATGAAG 
AAGCAGAAAG TGAAGACCAT CTTCCCGCAC ACTGCGGGCT CCAACAAGAC CTTACTCAGC 
TTTGCACAGG GAGATGTCAT CACGCTGCTC ATCCCCGAGG AGAAGGATGG CTGGCTCTAT 
GGAGAACACG ACGTGTCCAA GGCGAGGGGT TGGTTCCCGT CGTCGTACAC GAAGTTGCTG 
GAAGAAAATG AGACAGAAGC AGTGACCGTG CCCACGCCAA GCCCCACACC AGTGAGAAGC 
ATCAGCACCG TGAACTTGTC TGAGAATAGC AGTGTTGTCA TCCCCCCACC CGACTACTTG 
GAATGCTTGT CCATGGGGGC AGCTGCCGAC AGGAGAGCAG ATTCGGCCAG GACGACATCC 
ACCTTTAAGG CCCCAGCGTC CAAGCCCGAG ACCGCGGCTC CTAACGATGC CAACGGGACT 
GCAAAGCCGC CTTTTCTCAG CGGAGAAAAC CCCTTTGCCA CTGTGAAACT CCGCCCGACT 
GTGACGAATG ATCGCTCGGC ACCCATCATT CGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BAIAP2L1 ( NM_018842.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_061330.2 Homo sapiens BAR/IMD domain containing adaptor protein 2 like 1 (BAIAP2L1), mRNA.

Price & Availability↑

CloneID	OHu19617
Clone ID Related Accession (Same CDS sequence)	NM_018842.4 , NM_018842.5
Accession Version	NM_018842.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1536bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-04
Organism	Homo sapiens(human)
Product	brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI560834.1, DA442866.1, BC013888.2, AK074419.1 and BM977002.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_018842.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.72776.1, AF119666.2 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000005260.9/ ENSP00000005260.8 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTCCCGGG GGCCCGAGGA GGTGAACCGG CTCACGGAGA GCACCTACCG GAATGTTATG 
GAACAGTTCA ATCCTGGGCT GCGAAATTTA ATAAACCTGG GGAAAAATTA TGAGAAAGCT 
GTAAACGCTA TGATCCTGGC AGGAAAAGCC TACTACGATG GAGTGGCCAA GATCGGTGAG 
ATTGCCACTG GGTCCCCCGT GTCAACTGAA CTGGGACATG TCCTCATAGA GATTTCAAGT 
ACCCACAAGA AACTCAACGA GAGTCTTGAT GAAAATTTTA AAAAATTCCA CAAAGAGATT 
ATCCATGAGC TGGAGAAGAA GATAGAACTT GACGTGAAAT ATATGAACGC AACTCTAAAA 
AGATACCAAA CAGAACACAA GAATAAATTA GAGTCTTTGG AGAAATCCCA AGCTGAGTTG 
AAGAAGATCA GAAGGAAAAG CCAAGGAAGC CGAAACGCAC TCAAATATGA ACACAAAGAA 
ATTGAGTATG TGGAGACCGT TACTTCTCGT CAGAGTGAAA TCCAGAAATT CATTGCAGAT 
GGTTGCAAAG AGGCTCTGCT TGAAGAGAAG AGGCGCTTCT GCTTTCTGGT TGATAAGCAC 
TGTGGCTTTG CAAACCACAT ACATTATTAT CACTTACAGT CTGCAGAACT ACTGAATTCC 
AAGCTGCCTC GGTGGCAGGA GACCTGTGTT GATGCCATCA AAGTGCCAGA GAAAATCATG 
AATATGATCG AAGAAATAAA GACCCCAGCC TCTACCCCCG TGTCTGGAAC TCCTCAGGCT 
TCACCCATGA TCGAGAGAAG CAATGTGGTT AGGAAAGATT ACGACACCCT TTCTAAATGC 
TCACCAAAGA TGCCCCCCGC TCCTTCAGGC AGAGCATATA CCAGTCCCTT GATCGATATG 
TTTAATAACC CAGCCACGGC TGCCCCGAAT TCACAAAGGG TAAATAATTC AACAGGTACT 
TCCGAAGATC CCAGTTTACA GCGATCAGTT TCGGTTGCAA CGGGACTGAA CATGATGAAG 
AAGCAGAAAG TGAAGACCAT CTTCCCGCAC ACTGCGGGCT CCAACAAGAC CTTACTCAGC 
TTTGCACAGG GAGATGTCAT CACGCTGCTC ATCCCCGAGG AGAAGGATGG CTGGCTCTAT 
GGAGAACACG ACGTGTCCAA GGCGAGGGGT TGGTTCCCGT CGTCGTACAC GAAGTTGCTG 
GAAGAAAATG AGACAGAAGC AGTGACCGTG CCCACGCCAA GCCCCACACC AGTGAGAAGC 
ATCAGCACCG TGAACTTGTC TGAGAATAGC AGTGTTGTCA TCCCCCCACC CGACTACTTG 
GAATGCTTGT CCATGGGGGC AGCTGCCGAC AGGAGAGCAG ATTCGGCCAG GACGACATCC 
ACCTTTAAGG CCCCAGCGTC CAAGCCCGAG ACCGCGGCTC CTAACGATGC CAACGGGACT 
GCAAAGCCGC CTTTTCTCAG CGGAGAAAAC CCCTTTGCCA CTGTGAAACT CCGCCCGACT 
GTGACGAATG ATCGCTCGGC ACCCATCATT CGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_061330.2
CDS	239..1774
Translation	MSRGPEEVNRLTESTYRNVMEQFNPGLRNLINLGKNYEKAVNAMILAGKAYYDGVAKIGEIATGSPVSTELGHVLIEISSTHKKLNESLDENFKKFHKEIIHELEKKIELDVKYMNATLKRYQTEHKNKLESLEKSQAELKKIRRKSQGSRNALKYEHKEIEYVETVTSRQSEIQKFIADGCKEALLEEKRRFCFLVDKHCGFANHIHYYHLQSAELLNSKLPRWQETCVDAIKVPEKIMNMIEEIKTPASTPVSGTPQASPMIERSNVVRKDYDTLSKCSPKMPPAPSGRAYTSPLIDMFNNPATAAPNSQRVNNSTGTSEDPSLQRSVSVATGLNMMKKQKVKTIFPHTAGSNKTLLSFAQGDVITLLIPEEKDGWLYGEHDVSKARGWFPSSYTKLLEENETEAVTVPTPSPTPVRSISTVNLSENSSVVIPPPDYLECLSMGAAADRRADSARTTSTFKAPASKPETAAPNDANGTAKPPFLSGENPFATVKLRPTVTNDRSAPIIR

Target ORF information:

RefSeq Version	NM_018842.5
Organism	Homo sapiens(human)
Definition	Homo sapiens BAR/IMD domain containing adaptor protein 2 like 1 (BAIAP2L1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018842.5

ORF Insert Sequence:

ATGTCCCGGG GGCCCGAGGA GGTGAACCGG CTCACGGAGA GCACCTACCG GAATGTTATG 
GAACAGTTCA ATCCTGGGCT GCGAAATTTA ATAAACCTGG GGAAAAATTA TGAGAAAGCT 
GTAAACGCTA TGATCCTGGC AGGAAAAGCC TACTACGATG GAGTGGCCAA GATCGGTGAG 
ATTGCCACTG GGTCCCCCGT GTCAACTGAA CTGGGACATG TCCTCATAGA GATTTCAAGT 
ACCCACAAGA AACTCAACGA GAGTCTTGAT GAAAATTTTA AAAAATTCCA CAAAGAGATT 
ATCCATGAGC TGGAGAAGAA GATAGAACTT GACGTGAAAT ATATGAACGC AACTCTAAAA 
AGATACCAAA CAGAACACAA GAATAAATTA GAGTCTTTGG AGAAATCCCA AGCTGAGTTG 
AAGAAGATCA GAAGGAAAAG CCAAGGAAGC CGAAACGCAC TCAAATATGA ACACAAAGAA 
ATTGAGTATG TGGAGACCGT TACTTCTCGT CAGAGTGAAA TCCAGAAATT CATTGCAGAT 
GGTTGCAAAG AGGCTCTGCT TGAAGAGAAG AGGCGCTTCT GCTTTCTGGT TGATAAGCAC 
TGTGGCTTTG CAAACCACAT ACATTATTAT CACTTACAGT CTGCAGAACT ACTGAATTCC 
AAGCTGCCTC GGTGGCAGGA GACCTGTGTT GATGCCATCA AAGTGCCAGA GAAAATCATG 
AATATGATCG AAGAAATAAA GACCCCAGCC TCTACCCCCG TGTCTGGAAC TCCTCAGGCT 
TCACCCATGA TCGAGAGAAG CAATGTGGTT AGGAAAGATT ACGACACCCT TTCTAAATGC 
TCACCAAAGA TGCCCCCCGC TCCTTCAGGC AGAGCATATA CCAGTCCCTT GATCGATATG 
TTTAATAACC CAGCCACGGC TGCCCCGAAT TCACAAAGGG TAAATAATTC AACAGGTACT 
TCCGAAGATC CCAGTTTACA GCGATCAGTT TCGGTTGCAA CGGGACTGAA CATGATGAAG 
AAGCAGAAAG TGAAGACCAT CTTCCCGCAC ACTGCGGGCT CCAACAAGAC CTTACTCAGC 
TTTGCACAGG GAGATGTCAT CACGCTGCTC ATCCCCGAGG AGAAGGATGG CTGGCTCTAT 
GGAGAACACG ACGTGTCCAA GGCGAGGGGT TGGTTCCCGT CGTCGTACAC GAAGTTGCTG 
GAAGAAAATG AGACAGAAGC AGTGACCGTG CCCACGCCAA GCCCCACACC AGTGAGAAGC 
ATCAGCACCG TGAACTTGTC TGAGAATAGC AGTGTTGTCA TCCCCCCACC CGACTACTTG 
GAATGCTTGT CCATGGGGGC AGCTGCCGAC AGGAGAGCAG ATTCGGCCAG GACGACATCC 
ACCTTTAAGG CCCCAGCGTC CAAGCCCGAG ACCGCGGCTC CTAACGATGC CAACGGGACT 
GCAAAGCCGC CTTTTCTCAG CGGAGAAAAC CCCTTTGCCA CTGTGAAACT CCGCCCGACT 
GTGACGAATG ATCGCTCGGC ACCCATCATT CGATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The SH3 domain distinguishes the role of I-BAR proteins IRTKS and MIM in chemotactic response to serum.
Biochemical and biophysical research communications479(4)787-792(2016 Oct)
Li L,Liu H,Baxter SS,Gu N,Ji M,Zhan X

The Rho GTPase Rif signals through IRTKS, Eps8 and WAVE2 to generate dorsal membrane ruffles and filopodia.
Journal of cell science129(14)2829-40(2016 07)
Sudhaharan T,Sem KP,Liew HF,Yu YH,Goh WI,Chou AM,Ahmed S

Mechanism of Oncogenic Signal Activation by the Novel Fusion Kinase FGFR3-BAIAP2L1.
Molecular cancer therapeutics14(3)704-12(2015 Mar)
Nakanishi Y,Akiyama N,Tsukaguchi T,Fujii T,Satoh Y,Ishii N,Aoki M

BAI1-Associated Protein 2-Like 1 (BAIAP2L1) Is a Potential Biomarker in Ovarian Cancer.
PloS one10(7)e0133081(2015)
Chao A,Tsai CL,Jung SM,Chuang WC,Kao C,Hsu A,Chen SH,Lin CY,Lee YC,Lee YS,Wang TH,Wang HS,Lai CH

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BAIAP2L1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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