APOBR cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	APOBR
Entrez Gene ID	55911
Full Name	apolipoprotein B receptor
Synonyms	APOB100R,APOB48R
General protein information	Preferred Names apolipoprotein B receptor Names apolipoprotein B receptor apoB-48R apolipoprotein B-100 receptor apolipoprotein B-48 receptor apolipoprotein B100 receptor apolipoprotein B48 receptor
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 16 Map Location: 16p12.1
Summary	Apolipoprotein B48 receptor is a macrophage receptor that binds to the apolipoprotein B48 of dietary triglyceride (TG)-rich lipoproteins. This receptor may provide essential lipids, lipid-soluble vitamins and other nutrients to reticuloendothelial cells. If overwhelmed with elevated plasma triglyceride, the apolipoprotein B48 receptor may contribute to foam cell formation, endothelial dysfunction, and atherothrombogenesis. [provided by RefSeq, Jul 2008].
Disorder MIM:	605220

mRNA and Protein(s)

mRNA	Protein	Name
NM_018690.3	NP_061160.3	apolipoprotein B receptor
NM_018690.4	NP_061160.3	apolipoprotein B receptor

Pathways from BioSystems

Homologies

Homo sapiens (human)	APOBR	NP_061160.3
Mus musculus (house mouse)	Apobr	NP_612183.1
Rattus norvegicus (Norway rat)	Apobr	NP_001102624.1
Pan troglodytes (chimpanzee)	APOBR	XP_003954332.1
	APOBR	XP_001103862.1
Canis lupus familiaris (dog)	APOBR	XP_005621420.1
Bos taurus (cattle)	APOBR	XP_002698130.2

Gene Ontology
Bibliography

Related articles in PubMed

Analyses of non-synonymous obesity risk alleles in SH2B1 (rs7498665) and APOB48R (rs180743) in obese children and adolescents undergoing a 1-year lifestyle intervention.
Volckmar AL, P?tter C, Song JY, Graniger J, Knoll N, Wolters B, Hebebrand J, Scherag A, Reinehr T, Hinney A
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association121(6)334-7(2013 Jun)

Triglyceride-rich lipoprotein regulates APOB48 receptor gene expression in human THP-1 monocytes and macrophages.
Bermudez B, Lopez S, Varela LM, Ortega A, Pacheco YM, Moreda W, Moreno-Luna R, Abia R, Muriana FJ
The Journal of nutrition142(2)227-32(2012 Feb)

A high-fat meal promotes lipid-load and apolipoprotein B-48 receptor transcriptional activity in circulating monocytes.
Varela LM, Ortega A, Bermudez B, Lopez S, Pacheco YM, Villar J, Abia R, Muriana FJ
The American journal of clinical nutrition93(5)918-25(2011 May)

Defining the membrane proteome of NK cells.
Ghosh D, Lippert D, Krokhin O, Cortens JP, Wilkins JA
Journal of mass spectrometry : JMS45(1)1-25(2010 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The obesity risk alleles of non-synonymous SNPs at SH2B1 and APOB48R have no strong effect on weight loss-related phenotypes in overweight children after a 1-year lifestyle intervention.
Title: Analyses of non-synonymous obesity risk alleles in SH2B1 (rs7498665) and APOB48R (rs180743) in obese children and adolescents undergoing a 1-year lifestyle intervention.

These findings suggest that APOB48R represents a molecular target of postprandial lipoproteins via PPAR-dependent pathways in human monocytes and macrophages and advance an important link between postprandial metabolism of dietary fats and atherogenesis.
Title: Triglyceride-rich lipoprotein regulates APOB48 receptor gene expression in human THP-1 monocytes and macrophages.

investigation of apoB48R gene transcription in circulating monocytes: increase in apoB48R gene transcription following high-fat meal
Title: A high-fat meal promotes lipid-load and apolipoprotein B-48 receptor transcriptional activity in circulating monocytes.

Atherogenic remnant lipoproteins induced macrophage foam cell formation via apoB48R, indicating a potential role of apoB48R in atherosclerosis.
Title: Pitavastatin inhibits remnant lipoprotein-induced macrophage foam cell formation through ApoB48 receptor-dependent mechanism.

Nucleotide variations in the apolipoprotein B48 receptor gene is associated with hypercholesterolemia
Title: Association of nucleotide variations in the apolipoprotein B48 receptor gene (APOB48R) with hypercholesterolemia.

The following APOBR gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the APOBR cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu29180	NM_018690.4 Latest version!	Homo sapiens apolipoprotein B receptor (APOBR), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$559.30 $799.00
View Old Accession Versions >>
OHu29180	NM_018690.3	Homo sapiens apolipoprotein B receptor (APOBR), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$559.30 $799.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

APOBR ( NM_018690.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_061160.3 Homo sapiens apolipoprotein B receptor (APOBR), mRNA.

Price & Availability↑

CloneID	OHu29180
Clone ID Related Accession (Same CDS sequence)	NM_018690.3 , NM_018690.4
Accession Version	NM_018690.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3294bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	apolipoprotein B receptor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC138894.2. On Jul 16, 2011 this sequence version replaced NM_018690.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGACTTCC TCCGGCTATA CCTCCCTGGG CTGCACCAGG CCTTGAGGGG GGCACTGGAT 
TCCCTCGGCA CCTTTGTCTC CTACCTCCTG GGAGATGCAG TCCCCACTGT AGAGCGGGAG 
GCGCAGGCGG CTGAGGAACT GGGGGTGGTG GCGGTGGGAA AGACAGGGAA GATTGTAGAG 
GAGGAAGCCC AGGAGGACCT GGAGGGCCTT AGAGGCAGCC AAAACGAGGG GGCTGGAAGG 
CTGAGAGGGC CTGGAGATGA CAGAAGACAT GAAGTGGGGA GCTCAGCTGT AGAACAGACC 
TGGGGCTGGG GAGATGGCAG CTCCCATGGG TCCCAAGCAG AGAGGCAGGA CAGTGGGGCT 
GGGGAGACAG CCAAGGCTGC CAGGTGCCAG GAGCCAAGCG CCCACTTGGA GGCCAGAAAG 
AAATCCAAGG CAGGGTCTGG GGCTTGCCAA GACAGGAGCG GCCAAGCCCA GGAGAGGCAG 
GAGTCCCATG AGCAGGAAGT GAACAGAGAA GAGAGGCTGA GAAGCTGGGA ACAGGAGGAG 
GAGGAGGAAG AGGTCAGGGC AAGAGAGCCA GGGATGGCCA GAGGGGCGGA GTCAGAGTGG 
ACCTGGCATG GGGAGACGGA GGGGAAGGCT GGTGCTGTTG GGCCAAAGGC GGCAGGGGAC 
AACCGGGAGA TGGAGCAGGG GGTCAGGGAG GCAGATGCAG GGGAAACTGA GGAGCCTGGG 
GCCGAAGGGG CTGGGAAAGG AGAAGAGGTG GTAGTGGTGG AGAAGGCCTG TGAAAGCACT 
AGGGCATGGG GGACGTGGGG CCCAGGGGCA GAGCCTGAGG ACTGGGGAAT CTTAGGCAGA 
GAGGAGGCCA GGACAACCCC AGGTAGGGAA GAGGCCAGGG CAATTTTAGA TGGGGAGGAA 
GCCAGGACAA TCTCAGGCGG GGAGGAGGCT GAGACAGCCT CAGGCGGGGA GGAGGCTGAA 
ACAGCCTCAG GCGGGGAGGA GGCCGGGACA GCCTCGGGAG GGGAGGAGGC CGGGATAGCC 
TCAGGCGGGG AGGCTGGGAC AGCCTCAGGA GGGGAGGAGG CCGGGACAGC CTCAGGAGGG 
GAGGAGGCCG GGACAGCCTC AGGAGGGGAC GAGGCCTGGA CAACCTCAGG CAAAGAGGAG 
GCTGACCTGC TGGGAGTCAG ACAGACAGAA TATGGAGCAG TCCCAGGAGA AAGGCTCCTA 
GAGGCTACTG GAAAAGTCTG GGTCCTAGAG GAGGAGGGGG ATGAGGAGAG AGAGGCTGAG 
GTGAGCCCTT TCCCCAAACA GCCCCAGGTC CTGGGCACTG AAAGAACAGA AGAGGCTGCT 
GAGAGCCAGA CCGCAGGGAG GGAAGCTGTG GGAGGCCAGG AGGCAGGGGA GAGCTTTGAG 
GGCCAGGTAG ACCTGCGTGG TAAGGAGGCT GAGATGAGGC AGGACTTGGG GATCAGGGCC 
GACCGGGCCA GGATGGAAGA GCTGGTACAG GCAGAGGAGG CCCAGGAGGA GAGAGGGAGC 
AGCAGGGATC CAGTGGCTGA GCTGCCCTCA GATGGAGAGG CTGAAGGCAC TGCCGACTTG 
GAGGCAACTC CAGAGGCCAG GCCTGAGGAG GAGCTCACAG GGGAGGAGAG TGAGGCGGCC 
CAGACTAGCT GTGGCCTACT GGGCGTGGAA TGGGGTGGCC TCACACACAG CGTCACCAAA 
GGCCAAGGAC CTGAGCTGAT GGGGGGCGCC CAGACCCCAA CTAAGCAACC CGAGGAAAGG 
GAGGCAGGGG AGGTGGAGCT CATGGGAGTT CTGGCCCTGA GCAAAGAGGA GCAGGAGAGG 
AGCCTGGAGG CAGGTCCCAG GCACGCGGGG TCTGTAAAGC CTGAGGCCTC CGAGGCCTTC 
CCAGGAGCCT GGGAAAACCG CACGAGAAAG GACATGGAGA GAGGAAATAC TCAGGAGGAT 
GCGGCCGATG GCGAGCAGCG GGAGGAGGAG GAGACTGCGG GAGGCCAGAC CCTGGCGGCT 
GAGGCTGAAG GAGACCGAGA GTCTGAACTA TCAGAAGTCC CAGAGGCAGG CGGGGAGGGG 
CTGACAACCC AGGACGCGGG ATGTGGAACT GAGGAGGGAG AGGCATCTGT CTCAGAGAAC 
CAGGAGCTGG ACGGAAGCAC AGGGGCAGAC GCAGGGCCTT GCCCGTCACT GGGAGAGGCC 
TATGCCAGAG AAACTGAGGA TGAGGAGGCG GAGGCTGACA GAACATCCAG AAGAGGCTGG 
AGGCTGCAAG CGGTGGCTGT GGGCCTCCCG GACCGTGAGG ATGCACAGAC TGGCTCTGTG 
GCTGCTGGGA TTATGGGGGG TGATGTGGTC CCACACATCA GCGCTGCTGG CGCTGGTGAA 
GCTTTGGAAG GGGTGCTTGG GCAAGGCTGG GACTCGAAAG AAAAGGAAGA GGCAGCAGCA 
GGAGAGCATG CAGGTGGGCA AGAATTTGGT CTGGAGGGCT CAGCAGAGGA AGAGGTGACT 
GGCAGAGGCA GCCAAGTAGA GGCTTTTGAG TCCAGGGAGG GAGGACCTTG GGGAGGGCGG 
GTAGAGGCCG AGGAATCTGC AGGCGCAGAG GACAGCTGTG GGCTGGATCC CGCGGGCTCC 
CAGACAGCGA GGGCAGAGGG GATGGGAGCC ATGGTGGAGG CTGGGGGGCT TCTAGAAAAG 
TGGACGCTGT TGGAAGAAGA GGCTGTTGGA TGGCAGGAGA GAGAACAGAG GGAAGACAGT 
GAGGGGCGGT GTGGGGACTA CCACCCTGAG GGAGAGGCAC CAAGGCTCCT TGATGCAGAG 
GGTCTCATGG TGACCGGGGG CCGGAGGGCA GAGGCCAAGG AGACTGAGCC AGAAAGCCTG 
GAACATGTCA GGGGCCAGGA GGAGCAGCCA ACACACCAGG CCCCTGCAGA AGCTGCGCCG 
GAGTCAGTCG GGGAAGCCGA GACGGCTGAG GCCATGGGCA GTGCCAGAGG AGGTGCTGCC 
AACAGCTGGA GCGAGGCCCC GCTCCCCGGG TCCCTCCTAG ACGTCTCTGT CCCAAGGAGT 
CGCGTGCACC TCTCGAGAAG CTCCTCACAG CGTCGCTCCC GGCCCTCTTT TCGTCGGACT 
CCGGCCTGGG AGCAGCAGGA GGAGCCCCCA GCCCCCAACC CTCCTGAGGA GGAGCTGTCA 
GCTCCTGAGC AGAGACCCCT CCAGCTGGAG GAACCCCTGG AGCCAAGCCC TCTGAGGCAT 
GATGGGACCC CGGTGCCAGC CAGGAGAAGG CCCCTGGGAC ACGGGTTTGG CCTCGCGCAC 
CCTGGCATGA TGCAGGAGCT GCAAGCCCGT CTGGGCCGGC CTAAGCCCCA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_061160.3
CDS	34..3327
Translation	MDFLRLYLPGLHQALRGALDSLGTFVSYLLGDAVPTVEREAQAAEELGVVAVGKTGKIVEEEAQEDLEGLRGSQNEGAGRLRGPGDDRRHEVGSSAVEQTWGWGDGSSHGSQAERQDSGAGETAKAARCQEPSAHLEARKKSKAGSGACQDRSGQAQERQESHEQEVNREERLRSWEQEEEEEEVRAREPGMARGAESEWTWHGETEGKAGAVGPKAAGDNREMEQGVREADAGETEEPGAEGAGKGEEVVVVEKACESTRAWGTWGPGAEPEDWGILGREEARTTPGREEARAILDGEEARTISGGEEAETASGGEEAETASGGEEAGTASGGEEAGIASGGEAGTASGGEEAGTASGGEEAGTASGGDEAWTTSGKEEADLLGVRQTEYGAVPGERLLEATGKVWVLEEEGDEEREAEVSPFPKQPQVLGTERTEEAAESQTAGREAVGGQEAGESFEGQVDLRGKEAEMRQDLGIRADRARMEELVQAEEAQEERGSSRDPVAELPSDGEAEGTADLEATPEARPEEELTGEESEAAQTSCGLLGVEWGGLTHSVTKGQGPELMGGAQTPTKQPEEREAGEVELMGVLALSKEEQERSLEAGPRHAGSVKPEASEAFPGAWENRTRKDMERGNTQEDAADGEQREEEETAGGQTLAAEAEGDRESELSEVPEAGGEGLTTQDAGCGTEEGEASVSENQELDGSTGADAGPCPSLGEAYARETEDEEAEADRTSRRGWRLQAVAVGLPDREDAQTGSVAAGIMGGDVVPHISAAGAGEALEGVLGQGWDSKEKEEAAAGEHAGGQEFGLEGSAEEEVTGRGSQVEAFESREGGPWGGRVEAEESAGAEDSCGLDPAGSQTARAEGMGAMVEAGGLLEKWTLLEEEAVGWQEREQREDSEGRCGDYHPEGEAPRLLDAEGLMVTGGRRAEAKETEPESLEHVRGQEEQPTHQAPAEAAPESVGEAETAEAMGSARGGAANSWSEAPLPGSLLDVSVPRSRVHLSRSSSQRRSRPSFRRTPAWEQQEEPPAPNPPEEELSAPEQRPLQLEEPLEPSPLRHDGTPVPARRRPLGHGFGLAHPGMMQELQARLGRPKPQ

Target ORF information:

RefSeq Version	NM_018690.3
Organism	Homo sapiens(human)
Definition	Homo sapiens apolipoprotein B receptor (APOBR), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018690.3

ORF Insert Sequence:

ATGGACTTCC TCCGGCTATA CCTCCCTGGG CTGCACCAGG CCTTGAGGGG GGCACTGGAT 
TCCCTCGGCA CCTTTGTCTC CTACCTCCTG GGAGATGCAG TCCCCACTGT AGAGCGGGAG 
GCGCAGGCGG CTGAGGAACT GGGGGTGGTG GCGGTGGGAA AGACAGGGAA GATTGTAGAG 
GAGGAAGCCC AGGAGGACCT GGAGGGCCTT AGAGGCAGCC AAAACGAGGG GGCTGGAAGG 
CTGAGAGGGC CTGGAGATGA CAGAAGACAT GAAGTGGGGA GCTCAGCTGT AGAACAGACC 
TGGGGCTGGG GAGATGGCAG CTCCCATGGG TCCCAAGCAG AGAGGCAGGA CAGTGGGGCT 
GGGGAGACAG CCAAGGCTGC CAGGTGCCAG GAGCCAAGCG CCCACTTGGA GGCCAGAAAG 
AAATCCAAGG CAGGGTCTGG GGCTTGCCAA GACAGGAGCG GCCAAGCCCA GGAGAGGCAG 
GAGTCCCATG AGCAGGAAGT GAACAGAGAA GAGAGGCTGA GAAGCTGGGA ACAGGAGGAG 
GAGGAGGAAG AGGTCAGGGC AAGAGAGCCA GGGATGGCCA GAGGGGCGGA GTCAGAGTGG 
ACCTGGCATG GGGAGACGGA GGGGAAGGCT GGTGCTGTTG GGCCAAAGGC GGCAGGGGAC 
AACCGGGAGA TGGAGCAGGG GGTCAGGGAG GCAGATGCAG GGGAAACTGA GGAGCCTGGG 
GCCGAAGGGG CTGGGAAAGG AGAAGAGGTG GTAGTGGTGG AGAAGGCCTG TGAAAGCACT 
AGGGCATGGG GGACGTGGGG CCCAGGGGCA GAGCCTGAGG ACTGGGGAAT CTTAGGCAGA 
GAGGAGGCCA GGACAACCCC AGGTAGGGAA GAGGCCAGGG CAATTTTAGA TGGGGAGGAA 
GCCAGGACAA TCTCAGGCGG GGAGGAGGCT GAGACAGCCT CAGGCGGGGA GGAGGCTGAA 
ACAGCCTCAG GCGGGGAGGA GGCCGGGACA GCCTCGGGAG GGGAGGAGGC CGGGATAGCC 
TCAGGCGGGG AGGCTGGGAC AGCCTCAGGA GGGGAGGAGG CCGGGACAGC CTCAGGAGGG 
GAGGAGGCCG GGACAGCCTC AGGAGGGGAC GAGGCCTGGA CAACCTCAGG CAAAGAGGAG 
GCTGACCTGC TGGGAGTCAG ACAGACAGAA TATGGAGCAG TCCCAGGAGA AAGGCTCCTA 
GAGGCTACTG GAAAAGTCTG GGTCCTAGAG GAGGAGGGGG ATGAGGAGAG AGAGGCTGAG 
GTGAGCCCTT TCCCCAAACA GCCCCAGGTC CTGGGCACTG AAAGAACAGA AGAGGCTGCT 
GAGAGCCAGA CCGCAGGGAG GGAAGCTGTG GGAGGCCAGG AGGCAGGGGA GAGCTTTGAG 
GGCCAGGTAG ACCTGCGTGG TAAGGAGGCT GAGATGAGGC AGGACTTGGG GATCAGGGCC 
GACCGGGCCA GGATGGAAGA GCTGGTACAG GCAGAGGAGG CCCAGGAGGA GAGAGGGAGC 
AGCAGGGATC CAGTGGCTGA GCTGCCCTCA GATGGAGAGG CTGAAGGCAC TGCCGACTTG 
GAGGCAACTC CAGAGGCCAG GCCTGAGGAG GAGCTCACAG GGGAGGAGAG TGAGGCGGCC 
CAGACTAGCT GTGGCCTACT GGGCGTGGAA TGGGGTGGCC TCACACACAG CGTCACCAAA 
GGCCAAGGAC CTGAGCTGAT GGGGGGCGCC CAGACCCCAA CTAAGCAACC CGAGGAAAGG 
GAGGCAGGGG AGGTGGAGCT CATGGGAGTT CTGGCCCTGA GCAAAGAGGA GCAGGAGAGG 
AGCCTGGAGG CAGGTCCCAG GCACGCGGGG TCTGTAAAGC CTGAGGCCTC CGAGGCCTTC 
CCAGGAGCCT GGGAAAACCG CACGAGAAAG GACATGGAGA GAGGAAATAC TCAGGAGGAT 
GCGGCCGATG GCGAGCAGCG GGAGGAGGAG GAGACTGCGG GAGGCCAGAC CCTGGCGGCT 
GAGGCTGAAG GAGACCGAGA GTCTGAACTA TCAGAAGTCC CAGAGGCAGG CGGGGAGGGG 
CTGACAACCC AGGACGCGGG ATGTGGAACT GAGGAGGGAG AGGCATCTGT CTCAGAGAAC 
CAGGAGCTGG ACGGAAGCAC AGGGGCAGAC GCAGGGCCTT GCCCGTCACT GGGAGAGGCC 
TATGCCAGAG AAACTGAGGA TGAGGAGGCG GAGGCTGACA GAACATCCAG AAGAGGCTGG 
AGGCTGCAAG CGGTGGCTGT GGGCCTCCCG GACCGTGAGG ATGCACAGAC TGGCTCTGTG 
GCTGCTGGGA TTATGGGGGG TGATGTGGTC CCACACATCA GCGCTGCTGG CGCTGGTGAA 
GCTTTGGAAG GGGTGCTTGG GCAAGGCTGG GACTCGAAAG AAAAGGAAGA GGCAGCAGCA 
GGAGAGCATG CAGGTGGGCA AGAATTTGGT CTGGAGGGCT CAGCAGAGGA AGAGGTGACT 
GGCAGAGGCA GCCAAGTAGA GGCTTTTGAG TCCAGGGAGG GAGGACCTTG GGGAGGGCGG 
GTAGAGGCCG AGGAATCTGC AGGCGCAGAG GACAGCTGTG GGCTGGATCC CGCGGGCTCC 
CAGACAGCGA GGGCAGAGGG GATGGGAGCC ATGGTGGAGG CTGGGGGGCT TCTAGAAAAG 
TGGACGCTGT TGGAAGAAGA GGCTGTTGGA TGGCAGGAGA GAGAACAGAG GGAAGACAGT 
GAGGGGCGGT GTGGGGACTA CCACCCTGAG GGAGAGGCAC CAAGGCTCCT TGATGCAGAG 
GGTCTCATGG TGACCGGGGG CCGGAGGGCA GAGGCCAAGG AGACTGAGCC AGAAAGCCTG 
GAACATGTCA GGGGCCAGGA GGAGCAGCCA ACACACCAGG CCCCTGCAGA AGCTGCGCCG 
GAGTCAGTCG GGGAAGCCGA GACGGCTGAG GCCATGGGCA GTGCCAGAGG AGGTGCTGCC 
AACAGCTGGA GCGAGGCCCC GCTCCCCGGG TCCCTCCTAG ACGTCTCTGT CCCAAGGAGT 
CGCGTGCACC TCTCGAGAAG CTCCTCACAG CGTCGCTCCC GGCCCTCTTT TCGTCGGACT 
CCGGCCTGGG AGCAGCAGGA GGAGCCCCCA GCCCCCAACC CTCCTGAGGA GGAGCTGTCA 
GCTCCTGAGC AGAGACCCCT CCAGCTGGAG GAACCCCTGG AGCCAAGCCC TCTGAGGCAT 
GATGGGACCC CGGTGCCAGC CAGGAGAAGG CCCCTGGGAC ACGGGTTTGG CCTCGCGCAC 
CCTGGCATGA TGCAGGAGCT GCAAGCCCGT CTGGGCCGGC CTAAGCCCCA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

APOBR ( NM_018690.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_061160.3 Homo sapiens apolipoprotein B receptor (APOBR), mRNA.

Price & Availability↑

CloneID	OHu29180
Clone ID Related Accession (Same CDS sequence)	NM_018690.3 , NM_018690.4
Accession Version	NM_018690.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3294bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-05
Organism	Homo sapiens(human)
Product	apolipoprotein B receptor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC138894.2. On Nov 23, 2018 this sequence version replaced NM_018690.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000564831.6/ ENSP00000457539.1 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGACTTCC TCCGGCTATA CCTCCCTGGG CTGCACCAGG CCTTGAGGGG GGCACTGGAT 
TCCCTCGGCA CCTTTGTCTC CTACCTCCTG GGAGATGCAG TCCCCACTGT AGAGCGGGAG 
GCGCAGGCGG CTGAGGAACT GGGGGTGGTG GCGGTGGGAA AGACAGGGAA GATTGTAGAG 
GAGGAAGCCC AGGAGGACCT GGAGGGCCTT AGAGGCAGCC AAAACGAGGG GGCTGGAAGG 
CTGAGAGGGC CTGGAGATGA CAGAAGACAT GAAGTGGGGA GCTCAGCTGT AGAACAGACC 
TGGGGCTGGG GAGATGGCAG CTCCCATGGG TCCCAAGCAG AGAGGCAGGA CAGTGGGGCT 
GGGGAGACAG CCAAGGCTGC CAGGTGCCAG GAGCCAAGCG CCCACTTGGA GGCCAGAAAG 
AAATCCAAGG CAGGGTCTGG GGCTTGCCAA GACAGGAGCG GCCAAGCCCA GGAGAGGCAG 
GAGTCCCATG AGCAGGAAGT GAACAGAGAA GAGAGGCTGA GAAGCTGGGA ACAGGAGGAG 
GAGGAGGAAG AGGTCAGGGC AAGAGAGCCA GGGATGGCCA GAGGGGCGGA GTCAGAGTGG 
ACCTGGCATG GGGAGACGGA GGGGAAGGCT GGTGCTGTTG GGCCAAAGGC GGCAGGGGAC 
AACCGGGAGA TGGAGCAGGG GGTCAGGGAG GCAGATGCAG GGGAAACTGA GGAGCCTGGG 
GCCGAAGGGG CTGGGAAAGG AGAAGAGGTG GTAGTGGTGG AGAAGGCCTG TGAAAGCACT 
AGGGCATGGG GGACGTGGGG CCCAGGGGCA GAGCCTGAGG ACTGGGGAAT CTTAGGCAGA 
GAGGAGGCCA GGACAACCCC AGGTAGGGAA GAGGCCAGGG CAATTTTAGA TGGGGAGGAA 
GCCAGGACAA TCTCAGGCGG GGAGGAGGCT GAGACAGCCT CAGGCGGGGA GGAGGCTGAA 
ACAGCCTCAG GCGGGGAGGA GGCCGGGACA GCCTCGGGAG GGGAGGAGGC CGGGATAGCC 
TCAGGCGGGG AGGCTGGGAC AGCCTCAGGA GGGGAGGAGG CCGGGACAGC CTCAGGAGGG 
GAGGAGGCCG GGACAGCCTC AGGAGGGGAC GAGGCCTGGA CAACCTCAGG CAAAGAGGAG 
GCTGACCTGC TGGGAGTCAG ACAGACAGAA TATGGAGCAG TCCCAGGAGA AAGGCTCCTA 
GAGGCTACTG GAAAAGTCTG GGTCCTAGAG GAGGAGGGGG ATGAGGAGAG AGAGGCTGAG 
GTGAGCCCTT TCCCCAAACA GCCCCAGGTC CTGGGCACTG AAAGAACAGA AGAGGCTGCT 
GAGAGCCAGA CCGCAGGGAG GGAAGCTGTG GGAGGCCAGG AGGCAGGGGA GAGCTTTGAG 
GGCCAGGTAG ACCTGCGTGG TAAGGAGGCT GAGATGAGGC AGGACTTGGG GATCAGGGCC 
GACCGGGCCA GGATGGAAGA GCTGGTACAG GCAGAGGAGG CCCAGGAGGA GAGAGGGAGC 
AGCAGGGATC CAGTGGCTGA GCTGCCCTCA GATGGAGAGG CTGAAGGCAC TGCCGACTTG 
GAGGCAACTC CAGAGGCCAG GCCTGAGGAG GAGCTCACAG GGGAGGAGAG TGAGGCGGCC 
CAGACTAGCT GTGGCCTACT GGGCGTGGAA TGGGGTGGCC TCACACACAG CGTCACCAAA 
GGCCAAGGAC CTGAGCTGAT GGGGGGCGCC CAGACCCCAA CTAAGCAACC CGAGGAAAGG 
GAGGCAGGGG AGGTGGAGCT CATGGGAGTT CTGGCCCTGA GCAAAGAGGA GCAGGAGAGG 
AGCCTGGAGG CAGGTCCCAG GCACGCGGGG TCTGTAAAGC CTGAGGCCTC CGAGGCCTTC 
CCAGGAGCCT GGGAAAACCG CACGAGAAAG GACATGGAGA GAGGAAATAC TCAGGAGGAT 
GCGGCCGATG GCGAGCAGCG GGAGGAGGAG GAGACTGCGG GAGGCCAGAC CCTGGCGGCT 
GAGGCTGAAG GAGACCGAGA GTCTGAACTA TCAGAAGTCC CAGAGGCAGG CGGGGAGGGG 
CTGACAACCC AGGACGCGGG ATGTGGAACT GAGGAGGGAG AGGCATCTGT CTCAGAGAAC 
CAGGAGCTGG ACGGAAGCAC AGGGGCAGAC GCAGGGCCTT GCCCGTCACT GGGAGAGGCC 
TATGCCAGAG AAACTGAGGA TGAGGAGGCG GAGGCTGACA GAACATCCAG AAGAGGCTGG 
AGGCTGCAAG CGGTGGCTGT GGGCCTCCCG GACCGTGAGG ATGCACAGAC TGGCTCTGTG 
GCTGCTGGGA TTATGGGGGG TGATGTGGTC CCACACATCA GCGCTGCTGG CGCTGGTGAA 
GCTTTGGAAG GGGTGCTTGG GCAAGGCTGG GACTCGAAAG AAAAGGAAGA GGCAGCAGCA 
GGAGAGCATG CAGGTGGGCA AGAATTTGGT CTGGAGGGCT CAGCAGAGGA AGAGGTGACT 
GGCAGAGGCA GCCAAGTAGA GGCTTTTGAG TCCAGGGAGG GAGGACCTTG GGGAGGGCGG 
GTAGAGGCCG AGGAATCTGC AGGCGCAGAG GACAGCTGTG GGCTGGATCC CGCGGGCTCC 
CAGACAGCGA GGGCAGAGGG GATGGGAGCC ATGGTGGAGG CTGGGGGGCT TCTAGAAAAG 
TGGACGCTGT TGGAAGAAGA GGCTGTTGGA TGGCAGGAGA GAGAACAGAG GGAAGACAGT 
GAGGGGCGGT GTGGGGACTA CCACCCTGAG GGAGAGGCAC CAAGGCTCCT TGATGCAGAG 
GGTCTCATGG TGACCGGGGG CCGGAGGGCA GAGGCCAAGG AGACTGAGCC AGAAAGCCTG 
GAACATGTCA GGGGCCAGGA GGAGCAGCCA ACACACCAGG CCCCTGCAGA AGCTGCGCCG 
GAGTCAGTCG GGGAAGCCGA GACGGCTGAG GCCATGGGCA GTGCCAGAGG AGGTGCTGCC 
AACAGCTGGA GCGAGGCCCC GCTCCCCGGG TCCCTCCTAG ACGTCTCTGT CCCAAGGAGT 
CGCGTGCACC TCTCGAGAAG CTCCTCACAG CGTCGCTCCC GGCCCTCTTT TCGTCGGACT 
CCGGCCTGGG AGCAGCAGGA GGAGCCCCCA GCCCCCAACC CTCCTGAGGA GGAGCTGTCA 
GCTCCTGAGC AGAGACCCCT CCAGCTGGAG GAACCCCTGG AGCCAAGCCC TCTGAGGCAT 
GATGGGACCC CGGTGCCAGC CAGGAGAAGG CCCCTGGGAC ACGGGTTTGG CCTCGCGCAC 
CCTGGCATGA TGCAGGAGCT GCAAGCCCGT CTGGGCCGGC CTAAGCCCCA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_061160.3
CDS	40..3333
Translation	MDFLRLYLPGLHQALRGALDSLGTFVSYLLGDAVPTVEREAQAAEELGVVAVGKTGKIVEEEAQEDLEGLRGSQNEGAGRLRGPGDDRRHEVGSSAVEQTWGWGDGSSHGSQAERQDSGAGETAKAARCQEPSAHLEARKKSKAGSGACQDRSGQAQERQESHEQEVNREERLRSWEQEEEEEEVRAREPGMARGAESEWTWHGETEGKAGAVGPKAAGDNREMEQGVREADAGETEEPGAEGAGKGEEVVVVEKACESTRAWGTWGPGAEPEDWGILGREEARTTPGREEARAILDGEEARTISGGEEAETASGGEEAETASGGEEAGTASGGEEAGIASGGEAGTASGGEEAGTASGGEEAGTASGGDEAWTTSGKEEADLLGVRQTEYGAVPGERLLEATGKVWVLEEEGDEEREAEVSPFPKQPQVLGTERTEEAAESQTAGREAVGGQEAGESFEGQVDLRGKEAEMRQDLGIRADRARMEELVQAEEAQEERGSSRDPVAELPSDGEAEGTADLEATPEARPEEELTGEESEAAQTSCGLLGVEWGGLTHSVTKGQGPELMGGAQTPTKQPEEREAGEVELMGVLALSKEEQERSLEAGPRHAGSVKPEASEAFPGAWENRTRKDMERGNTQEDAADGEQREEEETAGGQTLAAEAEGDRESELSEVPEAGGEGLTTQDAGCGTEEGEASVSENQELDGSTGADAGPCPSLGEAYARETEDEEAEADRTSRRGWRLQAVAVGLPDREDAQTGSVAAGIMGGDVVPHISAAGAGEALEGVLGQGWDSKEKEEAAAGEHAGGQEFGLEGSAEEEVTGRGSQVEAFESREGGPWGGRVEAEESAGAEDSCGLDPAGSQTARAEGMGAMVEAGGLLEKWTLLEEEAVGWQEREQREDSEGRCGDYHPEGEAPRLLDAEGLMVTGGRRAEAKETEPESLEHVRGQEEQPTHQAPAEAAPESVGEAETAEAMGSARGGAANSWSEAPLPGSLLDVSVPRSRVHLSRSSSQRRSRPSFRRTPAWEQQEEPPAPNPPEEELSAPEQRPLQLEEPLEPSPLRHDGTPVPARRRPLGHGFGLAHPGMMQELQARLGRPKPQ

Target ORF information:

RefSeq Version	NM_018690.4
Organism	Homo sapiens(human)
Definition	Homo sapiens apolipoprotein B receptor (APOBR), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018690.4

ORF Insert Sequence:

ATGGACTTCC TCCGGCTATA CCTCCCTGGG CTGCACCAGG CCTTGAGGGG GGCACTGGAT 
TCCCTCGGCA CCTTTGTCTC CTACCTCCTG GGAGATGCAG TCCCCACTGT AGAGCGGGAG 
GCGCAGGCGG CTGAGGAACT GGGGGTGGTG GCGGTGGGAA AGACAGGGAA GATTGTAGAG 
GAGGAAGCCC AGGAGGACCT GGAGGGCCTT AGAGGCAGCC AAAACGAGGG GGCTGGAAGG 
CTGAGAGGGC CTGGAGATGA CAGAAGACAT GAAGTGGGGA GCTCAGCTGT AGAACAGACC 
TGGGGCTGGG GAGATGGCAG CTCCCATGGG TCCCAAGCAG AGAGGCAGGA CAGTGGGGCT 
GGGGAGACAG CCAAGGCTGC CAGGTGCCAG GAGCCAAGCG CCCACTTGGA GGCCAGAAAG 
AAATCCAAGG CAGGGTCTGG GGCTTGCCAA GACAGGAGCG GCCAAGCCCA GGAGAGGCAG 
GAGTCCCATG AGCAGGAAGT GAACAGAGAA GAGAGGCTGA GAAGCTGGGA ACAGGAGGAG 
GAGGAGGAAG AGGTCAGGGC AAGAGAGCCA GGGATGGCCA GAGGGGCGGA GTCAGAGTGG 
ACCTGGCATG GGGAGACGGA GGGGAAGGCT GGTGCTGTTG GGCCAAAGGC GGCAGGGGAC 
AACCGGGAGA TGGAGCAGGG GGTCAGGGAG GCAGATGCAG GGGAAACTGA GGAGCCTGGG 
GCCGAAGGGG CTGGGAAAGG AGAAGAGGTG GTAGTGGTGG AGAAGGCCTG TGAAAGCACT 
AGGGCATGGG GGACGTGGGG CCCAGGGGCA GAGCCTGAGG ACTGGGGAAT CTTAGGCAGA 
GAGGAGGCCA GGACAACCCC AGGTAGGGAA GAGGCCAGGG CAATTTTAGA TGGGGAGGAA 
GCCAGGACAA TCTCAGGCGG GGAGGAGGCT GAGACAGCCT CAGGCGGGGA GGAGGCTGAA 
ACAGCCTCAG GCGGGGAGGA GGCCGGGACA GCCTCGGGAG GGGAGGAGGC CGGGATAGCC 
TCAGGCGGGG AGGCTGGGAC AGCCTCAGGA GGGGAGGAGG CCGGGACAGC CTCAGGAGGG 
GAGGAGGCCG GGACAGCCTC AGGAGGGGAC GAGGCCTGGA CAACCTCAGG CAAAGAGGAG 
GCTGACCTGC TGGGAGTCAG ACAGACAGAA TATGGAGCAG TCCCAGGAGA AAGGCTCCTA 
GAGGCTACTG GAAAAGTCTG GGTCCTAGAG GAGGAGGGGG ATGAGGAGAG AGAGGCTGAG 
GTGAGCCCTT TCCCCAAACA GCCCCAGGTC CTGGGCACTG AAAGAACAGA AGAGGCTGCT 
GAGAGCCAGA CCGCAGGGAG GGAAGCTGTG GGAGGCCAGG AGGCAGGGGA GAGCTTTGAG 
GGCCAGGTAG ACCTGCGTGG TAAGGAGGCT GAGATGAGGC AGGACTTGGG GATCAGGGCC 
GACCGGGCCA GGATGGAAGA GCTGGTACAG GCAGAGGAGG CCCAGGAGGA GAGAGGGAGC 
AGCAGGGATC CAGTGGCTGA GCTGCCCTCA GATGGAGAGG CTGAAGGCAC TGCCGACTTG 
GAGGCAACTC CAGAGGCCAG GCCTGAGGAG GAGCTCACAG GGGAGGAGAG TGAGGCGGCC 
CAGACTAGCT GTGGCCTACT GGGCGTGGAA TGGGGTGGCC TCACACACAG CGTCACCAAA 
GGCCAAGGAC CTGAGCTGAT GGGGGGCGCC CAGACCCCAA CTAAGCAACC CGAGGAAAGG 
GAGGCAGGGG AGGTGGAGCT CATGGGAGTT CTGGCCCTGA GCAAAGAGGA GCAGGAGAGG 
AGCCTGGAGG CAGGTCCCAG GCACGCGGGG TCTGTAAAGC CTGAGGCCTC CGAGGCCTTC 
CCAGGAGCCT GGGAAAACCG CACGAGAAAG GACATGGAGA GAGGAAATAC TCAGGAGGAT 
GCGGCCGATG GCGAGCAGCG GGAGGAGGAG GAGACTGCGG GAGGCCAGAC CCTGGCGGCT 
GAGGCTGAAG GAGACCGAGA GTCTGAACTA TCAGAAGTCC CAGAGGCAGG CGGGGAGGGG 
CTGACAACCC AGGACGCGGG ATGTGGAACT GAGGAGGGAG AGGCATCTGT CTCAGAGAAC 
CAGGAGCTGG ACGGAAGCAC AGGGGCAGAC GCAGGGCCTT GCCCGTCACT GGGAGAGGCC 
TATGCCAGAG AAACTGAGGA TGAGGAGGCG GAGGCTGACA GAACATCCAG AAGAGGCTGG 
AGGCTGCAAG CGGTGGCTGT GGGCCTCCCG GACCGTGAGG ATGCACAGAC TGGCTCTGTG 
GCTGCTGGGA TTATGGGGGG TGATGTGGTC CCACACATCA GCGCTGCTGG CGCTGGTGAA 
GCTTTGGAAG GGGTGCTTGG GCAAGGCTGG GACTCGAAAG AAAAGGAAGA GGCAGCAGCA 
GGAGAGCATG CAGGTGGGCA AGAATTTGGT CTGGAGGGCT CAGCAGAGGA AGAGGTGACT 
GGCAGAGGCA GCCAAGTAGA GGCTTTTGAG TCCAGGGAGG GAGGACCTTG GGGAGGGCGG 
GTAGAGGCCG AGGAATCTGC AGGCGCAGAG GACAGCTGTG GGCTGGATCC CGCGGGCTCC 
CAGACAGCGA GGGCAGAGGG GATGGGAGCC ATGGTGGAGG CTGGGGGGCT TCTAGAAAAG 
TGGACGCTGT TGGAAGAAGA GGCTGTTGGA TGGCAGGAGA GAGAACAGAG GGAAGACAGT 
GAGGGGCGGT GTGGGGACTA CCACCCTGAG GGAGAGGCAC CAAGGCTCCT TGATGCAGAG 
GGTCTCATGG TGACCGGGGG CCGGAGGGCA GAGGCCAAGG AGACTGAGCC AGAAAGCCTG 
GAACATGTCA GGGGCCAGGA GGAGCAGCCA ACACACCAGG CCCCTGCAGA AGCTGCGCCG 
GAGTCAGTCG GGGAAGCCGA GACGGCTGAG GCCATGGGCA GTGCCAGAGG AGGTGCTGCC 
AACAGCTGGA GCGAGGCCCC GCTCCCCGGG TCCCTCCTAG ACGTCTCTGT CCCAAGGAGT 
CGCGTGCACC TCTCGAGAAG CTCCTCACAG CGTCGCTCCC GGCCCTCTTT TCGTCGGACT 
CCGGCCTGGG AGCAGCAGGA GGAGCCCCCA GCCCCCAACC CTCCTGAGGA GGAGCTGTCA 
GCTCCTGAGC AGAGACCCCT CCAGCTGGAG GAACCCCTGG AGCCAAGCCC TCTGAGGCAT 
GATGGGACCC CGGTGCCAGC CAGGAGAAGG CCCCTGGGAC ACGGGTTTGG CCTCGCGCAC 
CCTGGCATGA TGCAGGAGCT GCAAGCCCGT CTGGGCCGGC CTAAGCCCCA GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Analyses of non-synonymous obesity risk alleles in SH2B1 (rs7498665) and APOB48R (rs180743) in obese children and adolescents undergoing a 1-year lifestyle intervention.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association121(6)334-7(2013 Jun)
Volckmar AL,P?tter C,Song JY,Graniger J,Knoll N,Wolters B,Hebebrand J,Scherag A,Reinehr T,Hinney A

Triglyceride-rich lipoprotein regulates APOB48 receptor gene expression in human THP-1 monocytes and macrophages.
The Journal of nutrition142(2)227-32(2012 Feb)
Bermudez B,Lopez S,Varela LM,Ortega A,Pacheco YM,Moreda W,Moreno-Luna R,Abia R,Muriana FJ

A high-fat meal promotes lipid-load and apolipoprotein B-48 receptor transcriptional activity in circulating monocytes.
The American journal of clinical nutrition93(5)918-25(2011 May)
Varela LM,Ortega A,Bermudez B,Lopez S,Pacheco YM,Villar J,Abia R,Muriana FJ

Defining the membrane proteome of NK cells.
Journal of mass spectrometry : JMS45(1)1-25(2010 Jan)
Ghosh D,Lippert D,Krokhin O,Cortens JP,Wilkins JA

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APOBR cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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