VPS11 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	VPS11
Entrez Gene ID	55823
Full Name	VPS11, CORVET/HOPS core subunit
Synonyms	END1,HLD12,PEP5,RNF108,hVPS11
General protein information	Preferred Names VPS11, CORVET/HOPS core subunit Names vacuolar protein sorting-associated protein 11 homolog RING finger protein 108 vacuolar protein sorting 11 homolog
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 11 Map Location: 11q23.3
Summary	Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps11 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014].
Disorder MIM:	608549
Disorder Html:	Leukodystrophy, hypomyelinating, 12, 616683 (3)

mRNA and Protein(s)

mRNA	Protein	Name
XM_024448607.1	XP_024304375.1	vacuolar protein sorting-associated protein 11 homolog isoform X2
NM_001290185.2	NP_001277114.1	vacuolar protein sorting-associated protein 11 homolog isoform 2
XM_011542898.1	XP_011541200.1	vacuolar protein sorting-associated protein 11 homolog isoform X1
NM_001290185.1	NP_001277114.1	vacuolar protein sorting-associated protein 11 homolog isoform 2
NM_021729.5	NP_068375.3	vacuolar protein sorting-associated protein 11 homolog isoform 1
XM_011542899.3	XP_011541201.1	vacuolar protein sorting-associated protein 11 homolog isoform X1
XM_011542899.2	XP_011541201.1	vacuolar protein sorting-associated protein 11 homolog isoform X1

Pathways from BioSystems

Homologies

	VPS11	XP_001101032.1
Canis lupus familiaris (dog)	VPS11	XP_546492.2
Mus musculus (house mouse)	Vps11	NP_082165.1
Homo sapiens (human)	VPS11	NP_068375.3
Xenopus tropicalis (tropical clawed frog)	vps11	NP_001120879.1
Magnaporthe oryzae (rice blast fungus)	MGG_03283	XP_003716678.1
Arabidopsis thaliana (thale cress)	VPS11	NP_027676.1
Pan troglodytes (chimpanzee)	VPS11	XP_508805.2
Neurospora crassa	NCU05422	XP_963245.2
Oryza sativa (rice)	Os04g0382700	NP_001052609.1
Bos taurus (cattle)	VPS11	NP_001069684.1
Rattus norvegicus (Norway rat)	Vps11	NP_001101608.1
Gallus gallus (chicken)	VPS11	XP_417847.2
Danio rerio (zebrafish)	vps11	NP_001032797.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP002665	XP_312259.5

Gene Ontology
Bibliography

Related articles in PubMed

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

The second report of a new hypomyelinating disease due to a defect in the VPS11 gene discloses a massive lysosomal involvement.
H?rtnagel K, Kr?geloh-Mann I, Bornemann A, D?cker M, Biskup S, Mayrhofer H, Battke F, du Bois G, Harzer K
Journal of inherited metabolic disease39(6)849-857(2016 Nov)

A Founder Mutation in VPS11 Causes an Autosomal Recessive Leukoencephalopathy Linked to Autophagic Defects.
Zhang J, Lachance V, Schaffner A, Li X, Fedick A, Kaye LE, Liao J, Rosenfeld J, Yachelevich N, Chu ML, Mitchell WG, Boles RG, Moran E, Tokita M, Gorman E, Bagley K, Zhang W, Xia F, Leduc M, Yang Y, Eng C, Wong LJ, Schiffmann R, Diaz GA, Kornreich R, Thummel R, Wasserstein M, Yue Z, Edelmann L
PLoS genetics12(4)e1005848(2016 Apr)

A human interactome in three quantitative dimensions organized by stoichiometries and abundances.
Hein MY, Hubner NC, Poser I, Cox J, Nagaraj N, Toyoda Y, Gak IA, Weisswange I, Mansfeld J, Buchholz F, Hyman AA, Mann M
Cell163(3)712-23(2015 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Underlining the presumed pathogenic potential of VPS11 defects.
Title: The second report of a new hypomyelinating disease due to a defect in the VPS11 gene discloses a massive lysosomal involvement.

our study reveals a defect in VPS11 as the underlying etiology for an autosomal recessive leukoencephalopathy disorder associated with a dysfunctional autophagy-lysosome trafficking pathway
Title: A Founder Mutation in VPS11 Causes an Autosomal Recessive Leukoencephalopathy Linked to Autophagic Defects.

In Ashkenazi-Jewish patients, syndrome with hypomyelination, developmental delay, increasing appendicular spasticity, truncal hypotonia and acquired microcephaly is associated with VPS11 missense mutation, p.Cys846Gly.
Title: Hypomyelination and developmental delay associated with VPS11 mutation in Ashkenazi-Jewish patients.

Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
Title: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.

Observational study of gene-disease association. (HuGE Navigator)
Title: Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.

The following VPS11 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the VPS11 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu28243	NM_021729.5 Latest version!	Homo sapiens VPS11 core subunit of CORVET and HOPS complexes (VPS11), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$469.50-$657.30 $939.00
OHu69836	XM_011542898.1 Latest version!	Homo sapiens VPS11 core subunit of CORVET and HOPS complexes (VPS11), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu69836	XM_011542899.3 Latest version!	Homo sapiens VPS11 core subunit of CORVET and HOPS complexes (VPS11), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu106689	XM_024448607.1 Latest version!	Homo sapiens VPS11 core subunit of CORVET and HOPS complexes (VPS11), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu28242	NM_001290185.2 Latest version!	Homo sapiens VPS11 core subunit of CORVET and HOPS complexes (VPS11), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
View Old Accession Versions >>
OHu28242	NM_001290185.1	Homo sapiens VPS11 core subunit of CORVET and HOPS complexes (VPS11), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
OHu69836	XM_011542899.2	Homo sapiens VPS11, CORVET/HOPS core subunit (VPS11), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

VPS11 ( NM_021729.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_068375.3 Homo sapiens VPS11 core subunit of CORVET and HOPS complexes (VPS11), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu28243
Clone ID Related Accession (Same CDS sequence)	NM_021729.5
Accession Version	NM_021729.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2826bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-10
Organism	Homo sapiens(human)
Product	vacuolar protein sorting-associated protein 11 homolog isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI561271.1, AB027508.2, AK302973.1 and BC065563.1. This sequence is a reference standard in the RefSeqGene project. On Feb 28, 2014 this sequence version replaced NM_021729.4. Transcript Variant: This variant (1) encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC065563.1, SRR1803613.262414.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCCT ACCTGCAGTG GCGGCGCTTC GTTTTCTTCG ACAAGGAGCT GGTGAAGGAG 
CCGCTGAGCA ATGATGGGGC CGCTCCCGGG GCCACACCTG CTTCTGGATC CGCTGCTTCC 
AAGTTCCTTT GCCTCCCTCC TGGCATCACT GTCTGCGACT CAGGCCGAGG GAGCCTGGTC 
TTTGGAGATA TGGAAGGCCA GATCTGGTTC TTGCCACGTT CCCTACAGCT TACAGGCTTC 
CAAGCCTACA AACTACGGGT GACACACCTG TACCAACTGA AGCAGCACAA TATTCTGGCA 
TCTGTTGGAG AAGATGAAGA GGGCATCAAC CCCTTGGTTA AGATCTGGAA CCTGGAGAAG 
AGAGATGGTG GCAATCCACT CTGCACTCGA ATCTTCCCTG CTATTCCAGG AACAGAGCCA 
ACTGTTGTAT CTTGTTTGAC TGTCCATGAA AATCTCAACT TTATGGCCAT TGGTTTCACA 
GATGGCAGTG TTACATTGAA CAAAGGAGAC ATCACCCGGG ACCGGCATAG CAAGACCCAG 
ATTTTGCACA AGGGCAACTA TCCTGTAACT GGATTGGCCT TTCGCCAAGC AGGAAAGACC 
ACTCACTTGT TTGTTGTGAC AACAGAGAAC GTCCAGTCCT ATATAGTTTC TGGAAAAGAC 
TACCCTCGCG TGGAGTTGGA CACCCATGGT TGTGGCCTGC GCTGCTCAGC CCTAAGTGAC 
CCTTCTCAGG ACCTGCAGTT CATTGTGGCC GGGGATGAGT GTGTCTACTT GTACCAGCCT 
GATGAACGTG GGCCCTGCTT CGCCTTTGAG GGCCATAAGC TCATTGCCCA CTGGTTTAGA 
GGCTACCTTA TCATTGTCTC CCGTGACCGG AAGGTTTCTC CCAAGTCAGA GTTTACCAGC 
AGGGATTCAC AGAGCTCCGA CAAGCAGATT CTAAACATCT ATGACCTGTG CAACAAGTTC 
ATAGCCTATA GCACCGTCTT TGAGGATGTA GTGGATGTGC TTGCTGAGTG GGGCTCCCTG 
TACGTGCTGA CGCGGGATGG GCGGGTCCAC GCACTGCAGG AGAAGGACAC ACAGACCAAA 
CTGGAGATGC TGTTTAAGAA GAACCTATTT GAGATGGCGA TTAACCTTGC CAAGAGCCAG 
CATCTGGACA GTGATGGGCT GGCCCAGATT TTCATGCAGT ATGGAGACCA TCTCTACAGC 
AAGGGCAACC ACGATGGGGC TGTCCAGCAA TATATCCGAA CCATTGGAAA GTTGGAGCCA 
TCCTACGTGA TCCGCAAGTT TCTGGATGCC CAGCGCATTC ACAACCTGAC TGCCTACCTG 
CAGACCCTGC ACCGACAATC CCTGGCCAAT GCCGACCATA CCACCCTGCT CCTCAACTGC 
TATACCAAGC TCAAGGACAG CTCGAAGCTG GAGGAGTTCA TCAAGAAAAA GAGTGAGAGT 
GAAGTCCACT TTGATGTGGA GACAGCCATC AAGGTCCTCC GGCAGGCTGG CTACTACTCC 
CATGCCCTGT ATCTGGCGGA GAACCATGCA CATCATGAGT GGTACCTGAA GATCCAGCTA 
GAAGACATTA AGAATTATCA GGAAGCCCTT CGATACATCG GCAAGCTGCC TTTTGAGCAG 
GCAGAGAGCA ACATGAAGCG CTACGGCAAG ATCCTCATGC ACCACATACC AGAGCAGACA 
ACTCAGTTGC TGAAGGGACT TTGTACTGAT TATCGGCCCA GCCTCGAAGG CCGCAGCGAT 
AGGGAGGCCC CAGGCTGCAG GGCCAACTCT GAGGAGTTCA TCCCCATCTT TGCCAATAAC 
CCGCGAGAGC TGAAAGCCTT CCTAGAGCAC ATGAGTGAAG TGCAGCCAGA CTCACCCCAG 
GGGATCTACG ACACACTCCT TGAGCTGCGA CTGCAGAACT GGGCCCACGA GAAGGATCCA 
CAGGTCAAAG AGAAGCTTCA CGCAGAGGCC ATTTCCCTGC TGAAGAGTGG TCGCTTCTGC 
GACGTCTTTG ACAAGGCCCT GGTCCTGTGC CAGATGCACG ACTTCCAGGA TGGTGTCCTT 
TACCTTTATG AGCAGGGGAA GCTGTTCCAG CAGATCATGC ACTACCACAT GCAGCACGAG 
CAGTACCGGC AGGTCATCAG CGTGTGTGAG CGCCATGGGG AGCAGGACCC CTCCTTGTGG 
GAGCAGGCCC TCAGCTACTT CGCTCGCAAG GAGGAGGACT GCAAGGAGTA TGTGGCAGCT 
GTCCTCAAGC ATATCGAGAA CAAGAACCTC ATGCCACCTC TTCTAGTGGT GCAGACCCTG 
GCCCACAACT CCACAGCCAC ACTCTCCGTC ATCAGGGACT ACCTGGTCCA AAAACTACAG 
AAACAGAGCC AGCAGATTGC ACAGGATGAG CTGCGGGTGC GGCGGTACCG AGAGGAGACC 
ACCCGTATCC GCCAGGAGAT CCAAGAGCTC AAGGCCAGTC CTAAGATTTT CCAAAAGACC 
AAGTGCAGCA TCTGTAACAG TGCCTTGGAG TTGCCCTCAG TCCACTTCCT GTGTGGCCAC 
TCCTTCCACC AACACTGCTT TGAGAGTTAC TCGGAAAGTG ATGCTGACTG CCCCACCTGC 
CTCCCTGAAA ACCGGAAGGT CATGGATATG ATCCGGGCCC AGGAACAGAA ACGAGATCTC 
CATGATCAAT TCCAGCATCA GCTCAAGTGC TCCAATGACA GCTTTTCTGT GATTGCTGAC 
TACTTTGGCA GAGGTGTTTT CAACAAATTG ACTCTGCTGA CCGACCCTCC CACAGCCAGA 
CTGACCTCCA GCCTGGAGGC TGGGCTGCAA CGCGACCTAC TCATGCACTC CAGGAGGGGC 
ACTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_068375.3
CDS	73..2898
Translation	MAAYLQWRRFVFFDKELVKEPLSNDGAAPGATPASGSAASKFLCLPPGITVCDSGRGSLVFGDMEGQIWFLPRSLQLTGFQAYKLRVTHLYQLKQHNILASVGEDEEGINPLVKIWNLEKRDGGNPLCTRIFPAIPGTEPTVVSCLTVHENLNFMAIGFTDGSVTLNKGDITRDRHSKTQILHKGNYPVTGLAFRQAGKTTHLFVVTTENVQSYIVSGKDYPRVELDTHGCGLRCSALSDPSQDLQFIVAGDECVYLYQPDERGPCFAFEGHKLIAHWFRGYLIIVSRDRKVSPKSEFTSRDSQSSDKQILNIYDLCNKFIAYSTVFEDVVDVLAEWGSLYVLTRDGRVHALQEKDTQTKLEMLFKKNLFEMAINLAKSQHLDSDGLAQIFMQYGDHLYSKGNHDGAVQQYIRTIGKLEPSYVIRKFLDAQRIHNLTAYLQTLHRQSLANADHTTLLLNCYTKLKDSSKLEEFIKKKSESEVHFDVETAIKVLRQAGYYSHALYLAENHAHHEWYLKIQLEDIKNYQEALRYIGKLPFEQAESNMKRYGKILMHHIPEQTTQLLKGLCTDYRPSLEGRSDREAPGCRANSEEFIPIFANNPRELKAFLEHMSEVQPDSPQGIYDTLLELRLQNWAHEKDPQVKEKLHAEAISLLKSGRFCDVFDKALVLCQMHDFQDGVLYLYEQGKLFQQIMHYHMQHEQYRQVISVCERHGEQDPSLWEQALSYFARKEEDCKEYVAAVLKHIENKNLMPPLLVVQTLAHNSTATLSVIRDYLVQKLQKQSQQIAQDELRVRRYREETTRIRQEIQELKASPKIFQKTKCSICNSALELPSVHFLCGHSFHQHCFESYSESDADCPTCLPENRKVMDMIRAQEQKRDLHDQFQHQLKCSNDSFSVIADYFGRGVFNKLTLLTDPPTARLTSSLEAGLQRDLLMHSRRGT

Target ORF information:

RefSeq Version	NM_021729.5
Organism	Homo sapiens(human)
Definition	Homo sapiens VPS11 core subunit of CORVET and HOPS complexes (VPS11), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021729.5

ORF Insert Sequence:

ATGGCGGCCT ACCTGCAGTG GCGGCGCTTC GTTTTCTTCG ACAAGGAGCT GGTGAAGGAG 
CCGCTGAGCA ATGATGGGGC CGCTCCCGGG GCCACACCTG CTTCTGGATC CGCTGCTTCC 
AAGTTCCTTT GCCTCCCTCC TGGCATCACT GTCTGCGACT CAGGCCGAGG GAGCCTGGTC 
TTTGGAGATA TGGAAGGCCA GATCTGGTTC TTGCCACGTT CCCTACAGCT TACAGGCTTC 
CAAGCCTACA AACTACGGGT GACACACCTG TACCAACTGA AGCAGCACAA TATTCTGGCA 
TCTGTTGGAG AAGATGAAGA GGGCATCAAC CCCTTGGTTA AGATCTGGAA CCTGGAGAAG 
AGAGATGGTG GCAATCCACT CTGCACTCGA ATCTTCCCTG CTATTCCAGG AACAGAGCCA 
ACTGTTGTAT CTTGTTTGAC TGTCCATGAA AATCTCAACT TTATGGCCAT TGGTTTCACA 
GATGGCAGTG TTACATTGAA CAAAGGAGAC ATCACCCGGG ACCGGCATAG CAAGACCCAG 
ATTTTGCACA AGGGCAACTA TCCTGTAACT GGATTGGCCT TTCGCCAAGC AGGAAAGACC 
ACTCACTTGT TTGTTGTGAC AACAGAGAAC GTCCAGTCCT ATATAGTTTC TGGAAAAGAC 
TACCCTCGCG TGGAGTTGGA CACCCATGGT TGTGGCCTGC GCTGCTCAGC CCTAAGTGAC 
CCTTCTCAGG ACCTGCAGTT CATTGTGGCC GGGGATGAGT GTGTCTACTT GTACCAGCCT 
GATGAACGTG GGCCCTGCTT CGCCTTTGAG GGCCATAAGC TCATTGCCCA CTGGTTTAGA 
GGCTACCTTA TCATTGTCTC CCGTGACCGG AAGGTTTCTC CCAAGTCAGA GTTTACCAGC 
AGGGATTCAC AGAGCTCCGA CAAGCAGATT CTAAACATCT ATGACCTGTG CAACAAGTTC 
ATAGCCTATA GCACCGTCTT TGAGGATGTA GTGGATGTGC TTGCTGAGTG GGGCTCCCTG 
TACGTGCTGA CGCGGGATGG GCGGGTCCAC GCACTGCAGG AGAAGGACAC ACAGACCAAA 
CTGGAGATGC TGTTTAAGAA GAACCTATTT GAGATGGCGA TTAACCTTGC CAAGAGCCAG 
CATCTGGACA GTGATGGGCT GGCCCAGATT TTCATGCAGT ATGGAGACCA TCTCTACAGC 
AAGGGCAACC ACGATGGGGC TGTCCAGCAA TATATCCGAA CCATTGGAAA GTTGGAGCCA 
TCCTACGTGA TCCGCAAGTT TCTGGATGCC CAGCGCATTC ACAACCTGAC TGCCTACCTG 
CAGACCCTGC ACCGACAATC CCTGGCCAAT GCCGACCATA CCACCCTGCT CCTCAACTGC 
TATACCAAGC TCAAGGACAG CTCGAAGCTG GAGGAGTTCA TCAAGAAAAA GAGTGAGAGT 
GAAGTCCACT TTGATGTGGA GACAGCCATC AAGGTCCTCC GGCAGGCTGG CTACTACTCC 
CATGCCCTGT ATCTGGCGGA GAACCATGCA CATCATGAGT GGTACCTGAA GATCCAGCTA 
GAAGACATTA AGAATTATCA GGAAGCCCTT CGATACATCG GCAAGCTGCC TTTTGAGCAG 
GCAGAGAGCA ACATGAAGCG CTACGGCAAG ATCCTCATGC ACCACATACC AGAGCAGACA 
ACTCAGTTGC TGAAGGGACT TTGTACTGAT TATCGGCCCA GCCTCGAAGG CCGCAGCGAT 
AGGGAGGCCC CAGGCTGCAG GGCCAACTCT GAGGAGTTCA TCCCCATCTT TGCCAATAAC 
CCGCGAGAGC TGAAAGCCTT CCTAGAGCAC ATGAGTGAAG TGCAGCCAGA CTCACCCCAG 
GGGATCTACG ACACACTCCT TGAGCTGCGA CTGCAGAACT GGGCCCACGA GAAGGATCCA 
CAGGTCAAAG AGAAGCTTCA CGCAGAGGCC ATTTCCCTGC TGAAGAGTGG TCGCTTCTGC 
GACGTCTTTG ACAAGGCCCT GGTCCTGTGC CAGATGCACG ACTTCCAGGA TGGTGTCCTT 
TACCTTTATG AGCAGGGGAA GCTGTTCCAG CAGATCATGC ACTACCACAT GCAGCACGAG 
CAGTACCGGC AGGTCATCAG CGTGTGTGAG CGCCATGGGG AGCAGGACCC CTCCTTGTGG 
GAGCAGGCCC TCAGCTACTT CGCTCGCAAG GAGGAGGACT GCAAGGAGTA TGTGGCAGCT 
GTCCTCAAGC ATATCGAGAA CAAGAACCTC ATGCCACCTC TTCTAGTGGT GCAGACCCTG 
GCCCACAACT CCACAGCCAC ACTCTCCGTC ATCAGGGACT ACCTGGTCCA AAAACTACAG 
AAACAGAGCC AGCAGATTGC ACAGGATGAG CTGCGGGTGC GGCGGTACCG AGAGGAGACC 
ACCCGTATCC GCCAGGAGAT CCAAGAGCTC AAGGCCAGTC CTAAGATTTT CCAAAAGACC 
AAGTGCAGCA TCTGTAACAG TGCCTTGGAG TTGCCCTCAG TCCACTTCCT GTGTGGCCAC 
TCCTTCCACC AACACTGCTT TGAGAGTTAC TCGGAAAGTG ATGCTGACTG CCCCACCTGC 
CTCCCTGAAA ACCGGAAGGT CATGGATATG ATCCGGGCCC AGGAACAGAA ACGAGATCTC 
CATGATCAAT TCCAGCATCA GCTCAAGTGC TCCAATGACA GCTTTTCTGT GATTGCTGAC 
TACTTTGGCA GAGGTGTTTT CAACAAATTG ACTCTGCTGA CCGACCCTCC CACAGCCAGA 
CTGACCTCCA GCCTGGAGGC TGGGCTGCAA CGCGACCTAC TCATGCACTC CAGGAGGGGC 
ACTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

VPS11 ( XM_011542898.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011541200.1 Homo sapiens VPS11 core subunit of CORVET and HOPS complexes (VPS11), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu69836
Clone ID Related Accession (Same CDS sequence)	XM_011542898.1 , XM_011542899.3 , XM_011542899.2
Accession Version	XM_011542898.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1740bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	vacuolar protein sorting-associated protein 11 homolog isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGTTTA AGAAGAACCT ATTTGAGATG GCGATTAACC TTGCCAAGAG CCAGCATCTG 
GACAGTGATG GGCTGGCCCA GATTTTCATG CAGTATGGAG ACCATCTCTA CAGCAAGGGC 
AACCACGATG GGGCTGTCCA GCAATATATC CGAACCATTG GAAAGTTGGA GCCATCCTAC 
GTGATCCGCA AGTTTCTGGA TGCCCAGCGC ATTCACAACC TGACTGCCTA CCTGCAGACC 
CTGCACCGAC AATCCCTGGC CAATGCCGAC CATACCACCC TGCTCCTCAA CTGCTATACC 
AAGCTCAAGG ACAGCTCGAA GCTGGAGGAG TTCATCAAGA AAAAGAGTGA GAGTGAAGTC 
CACTTTGATG TGGAGACAGC CATCAAGGTC CTCCGGCAGG CTGGCTACTA CTCCCATGCC 
CTGTATCTGG CGGAGAACCA TGCACATCAT GAGTGGTACC TGAAGATCCA GCTAGAAGAC 
ATTAAGAATT ATCAGGAAGC CCTTCGATAC ATCGGCAAGC TGCCTTTTGA GCAGGCAGAG 
AGCAACATGA AGCGCTACGG CAAGATCCTC ATGCACCACA TACCAGAGCA GACAACTCAG 
TTGCTGAAGG GACTTTGTAC TGATTATCGG CCCAGCCTCG AAGGCCGCAG CGATAGGGAG 
GCCCCAGGCT GCAGGGCCAA CTCTGAGGAG TTCATCCCCA TCTTTGCCAA TAACCCGCGA 
GAGCTGAAAG CCTTCCTAGA GCACATGAGT GAAGTGCAGC CAGACTCACC CCAGGGGATC 
TACGACACAC TCCTTGAGCT GCGACTGCAG AACTGGGCCC ACGAGAAGGA TCCACAGGTC 
AAAGAGAAGC TTCACGCAGA GGCCATTTCC CTGCTGAAGA GTGGTCGCTT CTGCGACGTC 
TTTGACAAGG CCCTGGTCCT GTGCCAGATG CACGACTTCC AGGATGGTGT CCTTTACCTT 
TATGAGCAGG GGAAGCTGTT CCAGCAGATC ATGCACTACC ACATGCAGCA CGAGCAGTAC 
CGGCAGGTCA TCAGCGTGTG TGAGCGCCAT GGGGAGCAGG ACCCCTCCTT GTGGGAGCAG 
GCCCTCAGCT ACTTCGCTCG CAAGGAGGAG GACTGCAAGG AGTATGTGGC AGCTGTCCTC 
AAGCATATCG AGAACAAGAA CCTCATGCCA CCTCTTCTAG TGGTGCAGAC CCTGGCCCAC 
AACTCCACAG CCACACTCTC CGTCATCAGG GACTACCTGG TCCAAAAACT ACAGAAACAG 
AGCCAGCAGA TTGCACAGGA TGAGCTGCGG GTGCGGCGGT ACCGAGAGGA GACCACCCGT 
ATCCGCCAGG AGATCCAAGA GCTCAAGGCC AGTCCTAAGA TTTTCCAAAA GACCAAGTGC 
AGCATCTGTA ACAGTGCCTT GGAGTTGCCC TCAGTCCACT TCCTGTGTGG CCACTCCTTC 
CACCAACACT GCTTTGAGAG TTACTCGGAA AGTGATGCTG ACTGCCCCAC CTGCCTCCCT 
GAAAACCGGA AGGTCATGGA TATGATCCGG GCCCAGGAAC AGAAACGAGA TCTCCATGAT 
CAATTCCAGC ATCAGCTCAA GTGCTCCAAT GACAGCTTTT CTGTGATTGC TGACTACTTT 
GGCAGAGGTG TTTTCAACAA ATTGACTCTG CTGACCGACC CTCCCACAGC CAGACTGACC 
TCCAGCCTGG AGGCTGGGCT GCAACGCGAC CTACTCATGC ACTCCAGGAG GGGCACTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011541200.1
CDS	392..2131
Translation	MLFKKNLFEMAINLAKSQHLDSDGLAQIFMQYGDHLYSKGNHDGAVQQYIRTIGKLEPSYVIRKFLDAQRIHNLTAYLQTLHRQSLANADHTTLLLNCYTKLKDSSKLEEFIKKKSESEVHFDVETAIKVLRQAGYYSHALYLAENHAHHEWYLKIQLEDIKNYQEALRYIGKLPFEQAESNMKRYGKILMHHIPEQTTQLLKGLCTDYRPSLEGRSDREAPGCRANSEEFIPIFANNPRELKAFLEHMSEVQPDSPQGIYDTLLELRLQNWAHEKDPQVKEKLHAEAISLLKSGRFCDVFDKALVLCQMHDFQDGVLYLYEQGKLFQQIMHYHMQHEQYRQVISVCERHGEQDPSLWEQALSYFARKEEDCKEYVAAVLKHIENKNLMPPLLVVQTLAHNSTATLSVIRDYLVQKLQKQSQQIAQDELRVRRYREETTRIRQEIQELKASPKIFQKTKCSICNSALELPSVHFLCGHSFHQHCFESYSESDADCPTCLPENRKVMDMIRAQEQKRDLHDQFQHQLKCSNDSFSVIADYFGRGVFNKLTLLTDPPTARLTSSLEAGLQRDLLMHSRRGT

Target ORF information:

RefSeq Version	XM_011542898.1
Organism	Homo sapiens(human)
Definition	Homo sapiens VPS11 core subunit of CORVET and HOPS complexes (VPS11), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011542898.1

ORF Insert Sequence:

ATGCTGTTTA AGAAGAACCT ATTTGAGATG GCGATTAACC TTGCCAAGAG CCAGCATCTG 
GACAGTGATG GGCTGGCCCA GATTTTCATG CAGTATGGAG ACCATCTCTA CAGCAAGGGC 
AACCACGATG GGGCTGTCCA GCAATATATC CGAACCATTG GAAAGTTGGA GCCATCCTAC 
GTGATCCGCA AGTTTCTGGA TGCCCAGCGC ATTCACAACC TGACTGCCTA CCTGCAGACC 
CTGCACCGAC AATCCCTGGC CAATGCCGAC CATACCACCC TGCTCCTCAA CTGCTATACC 
AAGCTCAAGG ACAGCTCGAA GCTGGAGGAG TTCATCAAGA AAAAGAGTGA GAGTGAAGTC 
CACTTTGATG TGGAGACAGC CATCAAGGTC CTCCGGCAGG CTGGCTACTA CTCCCATGCC 
CTGTATCTGG CGGAGAACCA TGCACATCAT GAGTGGTACC TGAAGATCCA GCTAGAAGAC 
ATTAAGAATT ATCAGGAAGC CCTTCGATAC ATCGGCAAGC TGCCTTTTGA GCAGGCAGAG 
AGCAACATGA AGCGCTACGG CAAGATCCTC ATGCACCACA TACCAGAGCA GACAACTCAG 
TTGCTGAAGG GACTTTGTAC TGATTATCGG CCCAGCCTCG AAGGCCGCAG CGATAGGGAG 
GCCCCAGGCT GCAGGGCCAA CTCTGAGGAG TTCATCCCCA TCTTTGCCAA TAACCCGCGA 
GAGCTGAAAG CCTTCCTAGA GCACATGAGT GAAGTGCAGC CAGACTCACC CCAGGGGATC 
TACGACACAC TCCTTGAGCT GCGACTGCAG AACTGGGCCC ACGAGAAGGA TCCACAGGTC 
AAAGAGAAGC TTCACGCAGA GGCCATTTCC CTGCTGAAGA GTGGTCGCTT CTGCGACGTC 
TTTGACAAGG CCCTGGTCCT GTGCCAGATG CACGACTTCC AGGATGGTGT CCTTTACCTT 
TATGAGCAGG GGAAGCTGTT CCAGCAGATC ATGCACTACC ACATGCAGCA CGAGCAGTAC 
CGGCAGGTCA TCAGCGTGTG TGAGCGCCAT GGGGAGCAGG ACCCCTCCTT GTGGGAGCAG 
GCCCTCAGCT ACTTCGCTCG CAAGGAGGAG GACTGCAAGG AGTATGTGGC AGCTGTCCTC 
AAGCATATCG AGAACAAGAA CCTCATGCCA CCTCTTCTAG TGGTGCAGAC CCTGGCCCAC 
AACTCCACAG CCACACTCTC CGTCATCAGG GACTACCTGG TCCAAAAACT ACAGAAACAG 
AGCCAGCAGA TTGCACAGGA TGAGCTGCGG GTGCGGCGGT ACCGAGAGGA GACCACCCGT 
ATCCGCCAGG AGATCCAAGA GCTCAAGGCC AGTCCTAAGA TTTTCCAAAA GACCAAGTGC 
AGCATCTGTA ACAGTGCCTT GGAGTTGCCC TCAGTCCACT TCCTGTGTGG CCACTCCTTC 
CACCAACACT GCTTTGAGAG TTACTCGGAA AGTGATGCTG ACTGCCCCAC CTGCCTCCCT 
GAAAACCGGA AGGTCATGGA TATGATCCGG GCCCAGGAAC AGAAACGAGA TCTCCATGAT 
CAATTCCAGC ATCAGCTCAA GTGCTCCAAT GACAGCTTTT CTGTGATTGC TGACTACTTT 
GGCAGAGGTG TTTTCAACAA ATTGACTCTG CTGACCGACC CTCCCACAGC CAGACTGACC 
TCCAGCCTGG AGGCTGGGCT GCAACGCGAC CTACTCATGC ACTCCAGGAG GGGCACTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

VPS11 ( XM_011542899.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_011541201.1 Homo sapiens VPS11 core subunit of CORVET and HOPS complexes (VPS11), transcript variant X2, mRNA.

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CloneID	OHu69836
Clone ID Related Accession (Same CDS sequence)	XM_011542898.1 , XM_011542899.3 , XM_011542899.2
Accession Version	XM_011542899.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1740bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	vacuolar protein sorting-associated protein 11 homolog isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011542899.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGTTTA AGAAGAACCT ATTTGAGATG GCGATTAACC TTGCCAAGAG CCAGCATCTG 
GACAGTGATG GGCTGGCCCA GATTTTCATG CAGTATGGAG ACCATCTCTA CAGCAAGGGC 
AACCACGATG GGGCTGTCCA GCAATATATC CGAACCATTG GAAAGTTGGA GCCATCCTAC 
GTGATCCGCA AGTTTCTGGA TGCCCAGCGC ATTCACAACC TGACTGCCTA CCTGCAGACC 
CTGCACCGAC AATCCCTGGC CAATGCCGAC CATACCACCC TGCTCCTCAA CTGCTATACC 
AAGCTCAAGG ACAGCTCGAA GCTGGAGGAG TTCATCAAGA AAAAGAGTGA GAGTGAAGTC 
CACTTTGATG TGGAGACAGC CATCAAGGTC CTCCGGCAGG CTGGCTACTA CTCCCATGCC 
CTGTATCTGG CGGAGAACCA TGCACATCAT GAGTGGTACC TGAAGATCCA GCTAGAAGAC 
ATTAAGAATT ATCAGGAAGC CCTTCGATAC ATCGGCAAGC TGCCTTTTGA GCAGGCAGAG 
AGCAACATGA AGCGCTACGG CAAGATCCTC ATGCACCACA TACCAGAGCA GACAACTCAG 
TTGCTGAAGG GACTTTGTAC TGATTATCGG CCCAGCCTCG AAGGCCGCAG CGATAGGGAG 
GCCCCAGGCT GCAGGGCCAA CTCTGAGGAG TTCATCCCCA TCTTTGCCAA TAACCCGCGA 
GAGCTGAAAG CCTTCCTAGA GCACATGAGT GAAGTGCAGC CAGACTCACC CCAGGGGATC 
TACGACACAC TCCTTGAGCT GCGACTGCAG AACTGGGCCC ACGAGAAGGA TCCACAGGTC 
AAAGAGAAGC TTCACGCAGA GGCCATTTCC CTGCTGAAGA GTGGTCGCTT CTGCGACGTC 
TTTGACAAGG CCCTGGTCCT GTGCCAGATG CACGACTTCC AGGATGGTGT CCTTTACCTT 
TATGAGCAGG GGAAGCTGTT CCAGCAGATC ATGCACTACC ACATGCAGCA CGAGCAGTAC 
CGGCAGGTCA TCAGCGTGTG TGAGCGCCAT GGGGAGCAGG ACCCCTCCTT GTGGGAGCAG 
GCCCTCAGCT ACTTCGCTCG CAAGGAGGAG GACTGCAAGG AGTATGTGGC AGCTGTCCTC 
AAGCATATCG AGAACAAGAA CCTCATGCCA CCTCTTCTAG TGGTGCAGAC CCTGGCCCAC 
AACTCCACAG CCACACTCTC CGTCATCAGG GACTACCTGG TCCAAAAACT ACAGAAACAG 
AGCCAGCAGA TTGCACAGGA TGAGCTGCGG GTGCGGCGGT ACCGAGAGGA GACCACCCGT 
ATCCGCCAGG AGATCCAAGA GCTCAAGGCC AGTCCTAAGA TTTTCCAAAA GACCAAGTGC 
AGCATCTGTA ACAGTGCCTT GGAGTTGCCC TCAGTCCACT TCCTGTGTGG CCACTCCTTC 
CACCAACACT GCTTTGAGAG TTACTCGGAA AGTGATGCTG ACTGCCCCAC CTGCCTCCCT 
GAAAACCGGA AGGTCATGGA TATGATCCGG GCCCAGGAAC AGAAACGAGA TCTCCATGAT 
CAATTCCAGC ATCAGCTCAA GTGCTCCAAT GACAGCTTTT CTGTGATTGC TGACTACTTT 
GGCAGAGGTG TTTTCAACAA ATTGACTCTG CTGACCGACC CTCCCACAGC CAGACTGACC 
TCCAGCCTGG AGGCTGGGCT GCAACGCGAC CTACTCATGC ACTCCAGGAG GGGCACTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011541201.1
CDS	1260..2999
Translation	MLFKKNLFEMAINLAKSQHLDSDGLAQIFMQYGDHLYSKGNHDGAVQQYIRTIGKLEPSYVIRKFLDAQRIHNLTAYLQTLHRQSLANADHTTLLLNCYTKLKDSSKLEEFIKKKSESEVHFDVETAIKVLRQAGYYSHALYLAENHAHHEWYLKIQLEDIKNYQEALRYIGKLPFEQAESNMKRYGKILMHHIPEQTTQLLKGLCTDYRPSLEGRSDREAPGCRANSEEFIPIFANNPRELKAFLEHMSEVQPDSPQGIYDTLLELRLQNWAHEKDPQVKEKLHAEAISLLKSGRFCDVFDKALVLCQMHDFQDGVLYLYEQGKLFQQIMHYHMQHEQYRQVISVCERHGEQDPSLWEQALSYFARKEEDCKEYVAAVLKHIENKNLMPPLLVVQTLAHNSTATLSVIRDYLVQKLQKQSQQIAQDELRVRRYREETTRIRQEIQELKASPKIFQKTKCSICNSALELPSVHFLCGHSFHQHCFESYSESDADCPTCLPENRKVMDMIRAQEQKRDLHDQFQHQLKCSNDSFSVIADYFGRGVFNKLTLLTDPPTARLTSSLEAGLQRDLLMHSRRGT

Target ORF information:

RefSeq Version	XM_011542899.3
Organism	Homo sapiens(human)
Definition	Homo sapiens VPS11 core subunit of CORVET and HOPS complexes (VPS11), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011542899.3

ORF Insert Sequence:

ATGCTGTTTA AGAAGAACCT ATTTGAGATG GCGATTAACC TTGCCAAGAG CCAGCATCTG 
GACAGTGATG GGCTGGCCCA GATTTTCATG CAGTATGGAG ACCATCTCTA CAGCAAGGGC 
AACCACGATG GGGCTGTCCA GCAATATATC CGAACCATTG GAAAGTTGGA GCCATCCTAC 
GTGATCCGCA AGTTTCTGGA TGCCCAGCGC ATTCACAACC TGACTGCCTA CCTGCAGACC 
CTGCACCGAC AATCCCTGGC CAATGCCGAC CATACCACCC TGCTCCTCAA CTGCTATACC 
AAGCTCAAGG ACAGCTCGAA GCTGGAGGAG TTCATCAAGA AAAAGAGTGA GAGTGAAGTC 
CACTTTGATG TGGAGACAGC CATCAAGGTC CTCCGGCAGG CTGGCTACTA CTCCCATGCC 
CTGTATCTGG CGGAGAACCA TGCACATCAT GAGTGGTACC TGAAGATCCA GCTAGAAGAC 
ATTAAGAATT ATCAGGAAGC CCTTCGATAC ATCGGCAAGC TGCCTTTTGA GCAGGCAGAG 
AGCAACATGA AGCGCTACGG CAAGATCCTC ATGCACCACA TACCAGAGCA GACAACTCAG 
TTGCTGAAGG GACTTTGTAC TGATTATCGG CCCAGCCTCG AAGGCCGCAG CGATAGGGAG 
GCCCCAGGCT GCAGGGCCAA CTCTGAGGAG TTCATCCCCA TCTTTGCCAA TAACCCGCGA 
GAGCTGAAAG CCTTCCTAGA GCACATGAGT GAAGTGCAGC CAGACTCACC CCAGGGGATC 
TACGACACAC TCCTTGAGCT GCGACTGCAG AACTGGGCCC ACGAGAAGGA TCCACAGGTC 
AAAGAGAAGC TTCACGCAGA GGCCATTTCC CTGCTGAAGA GTGGTCGCTT CTGCGACGTC 
TTTGACAAGG CCCTGGTCCT GTGCCAGATG CACGACTTCC AGGATGGTGT CCTTTACCTT 
TATGAGCAGG GGAAGCTGTT CCAGCAGATC ATGCACTACC ACATGCAGCA CGAGCAGTAC 
CGGCAGGTCA TCAGCGTGTG TGAGCGCCAT GGGGAGCAGG ACCCCTCCTT GTGGGAGCAG 
GCCCTCAGCT ACTTCGCTCG CAAGGAGGAG GACTGCAAGG AGTATGTGGC AGCTGTCCTC 
AAGCATATCG AGAACAAGAA CCTCATGCCA CCTCTTCTAG TGGTGCAGAC CCTGGCCCAC 
AACTCCACAG CCACACTCTC CGTCATCAGG GACTACCTGG TCCAAAAACT ACAGAAACAG 
AGCCAGCAGA TTGCACAGGA TGAGCTGCGG GTGCGGCGGT ACCGAGAGGA GACCACCCGT 
ATCCGCCAGG AGATCCAAGA GCTCAAGGCC AGTCCTAAGA TTTTCCAAAA GACCAAGTGC 
AGCATCTGTA ACAGTGCCTT GGAGTTGCCC TCAGTCCACT TCCTGTGTGG CCACTCCTTC 
CACCAACACT GCTTTGAGAG TTACTCGGAA AGTGATGCTG ACTGCCCCAC CTGCCTCCCT 
GAAAACCGGA AGGTCATGGA TATGATCCGG GCCCAGGAAC AGAAACGAGA TCTCCATGAT 
CAATTCCAGC ATCAGCTCAA GTGCTCCAAT GACAGCTTTT CTGTGATTGC TGACTACTTT 
GGCAGAGGTG TTTTCAACAA ATTGACTCTG CTGACCGACC CTCCCACAGC CAGACTGACC 
TCCAGCCTGG AGGCTGGGCT GCAACGCGAC CTACTCATGC ACTCCAGGAG GGGCACTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

VPS11 ( XM_011542899.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011541201.1 Homo sapiens VPS11, CORVET/HOPS core subunit (VPS11), transcript variant X2, mRNA.

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CloneID	OHu69836
Clone ID Related Accession (Same CDS sequence)	XM_011542898.1 , XM_011542899.3 , XM_011542899.2
Accession Version	XM_011542899.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1740bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	vacuolar protein sorting-associated protein 11 homolog isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011542899.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGTTTA AGAAGAACCT ATTTGAGATG GCGATTAACC TTGCCAAGAG CCAGCATCTG 
GACAGTGATG GGCTGGCCCA GATTTTCATG CAGTATGGAG ACCATCTCTA CAGCAAGGGC 
AACCACGATG GGGCTGTCCA GCAATATATC CGAACCATTG GAAAGTTGGA GCCATCCTAC 
GTGATCCGCA AGTTTCTGGA TGCCCAGCGC ATTCACAACC TGACTGCCTA CCTGCAGACC 
CTGCACCGAC AATCCCTGGC CAATGCCGAC CATACCACCC TGCTCCTCAA CTGCTATACC 
AAGCTCAAGG ACAGCTCGAA GCTGGAGGAG TTCATCAAGA AAAAGAGTGA GAGTGAAGTC 
CACTTTGATG TGGAGACAGC CATCAAGGTC CTCCGGCAGG CTGGCTACTA CTCCCATGCC 
CTGTATCTGG CGGAGAACCA TGCACATCAT GAGTGGTACC TGAAGATCCA GCTAGAAGAC 
ATTAAGAATT ATCAGGAAGC CCTTCGATAC ATCGGCAAGC TGCCTTTTGA GCAGGCAGAG 
AGCAACATGA AGCGCTACGG CAAGATCCTC ATGCACCACA TACCAGAGCA GACAACTCAG 
TTGCTGAAGG GACTTTGTAC TGATTATCGG CCCAGCCTCG AAGGCCGCAG CGATAGGGAG 
GCCCCAGGCT GCAGGGCCAA CTCTGAGGAG TTCATCCCCA TCTTTGCCAA TAACCCGCGA 
GAGCTGAAAG CCTTCCTAGA GCACATGAGT GAAGTGCAGC CAGACTCACC CCAGGGGATC 
TACGACACAC TCCTTGAGCT GCGACTGCAG AACTGGGCCC ACGAGAAGGA TCCACAGGTC 
AAAGAGAAGC TTCACGCAGA GGCCATTTCC CTGCTGAAGA GTGGTCGCTT CTGCGACGTC 
TTTGACAAGG CCCTGGTCCT GTGCCAGATG CACGACTTCC AGGATGGTGT CCTTTACCTT 
TATGAGCAGG GGAAGCTGTT CCAGCAGATC ATGCACTACC ACATGCAGCA CGAGCAGTAC 
CGGCAGGTCA TCAGCGTGTG TGAGCGCCAT GGGGAGCAGG ACCCCTCCTT GTGGGAGCAG 
GCCCTCAGCT ACTTCGCTCG CAAGGAGGAG GACTGCAAGG AGTATGTGGC AGCTGTCCTC 
AAGCATATCG AGAACAAGAA CCTCATGCCA CCTCTTCTAG TGGTGCAGAC CCTGGCCCAC 
AACTCCACAG CCACACTCTC CGTCATCAGG GACTACCTGG TCCAAAAACT ACAGAAACAG 
AGCCAGCAGA TTGCACAGGA TGAGCTGCGG GTGCGGCGGT ACCGAGAGGA GACCACCCGT 
ATCCGCCAGG AGATCCAAGA GCTCAAGGCC AGTCCTAAGA TTTTCCAAAA GACCAAGTGC 
AGCATCTGTA ACAGTGCCTT GGAGTTGCCC TCAGTCCACT TCCTGTGTGG CCACTCCTTC 
CACCAACACT GCTTTGAGAG TTACTCGGAA AGTGATGCTG ACTGCCCCAC CTGCCTCCCT 
GAAAACCGGA AGGTCATGGA TATGATCCGG GCCCAGGAAC AGAAACGAGA TCTCCATGAT 
CAATTCCAGC ATCAGCTCAA GTGCTCCAAT GACAGCTTTT CTGTGATTGC TGACTACTTT 
GGCAGAGGTG TTTTCAACAA ATTGACTCTG CTGACCGACC CTCCCACAGC CAGACTGACC 
TCCAGCCTGG AGGCTGGGCT GCAACGCGAC CTACTCATGC ACTCCAGGAG GGGCACTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011541201.1
CDS	1258..2997
Translation	MLFKKNLFEMAINLAKSQHLDSDGLAQIFMQYGDHLYSKGNHDGAVQQYIRTIGKLEPSYVIRKFLDAQRIHNLTAYLQTLHRQSLANADHTTLLLNCYTKLKDSSKLEEFIKKKSESEVHFDVETAIKVLRQAGYYSHALYLAENHAHHEWYLKIQLEDIKNYQEALRYIGKLPFEQAESNMKRYGKILMHHIPEQTTQLLKGLCTDYRPSLEGRSDREAPGCRANSEEFIPIFANNPRELKAFLEHMSEVQPDSPQGIYDTLLELRLQNWAHEKDPQVKEKLHAEAISLLKSGRFCDVFDKALVLCQMHDFQDGVLYLYEQGKLFQQIMHYHMQHEQYRQVISVCERHGEQDPSLWEQALSYFARKEEDCKEYVAAVLKHIENKNLMPPLLVVQTLAHNSTATLSVIRDYLVQKLQKQSQQIAQDELRVRRYREETTRIRQEIQELKASPKIFQKTKCSICNSALELPSVHFLCGHSFHQHCFESYSESDADCPTCLPENRKVMDMIRAQEQKRDLHDQFQHQLKCSNDSFSVIADYFGRGVFNKLTLLTDPPTARLTSSLEAGLQRDLLMHSRRGT

Target ORF information:

RefSeq Version	XM_011542899.2
Organism	Homo sapiens(human)
Definition	Homo sapiens VPS11, CORVET/HOPS core subunit (VPS11), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011542899.2

ORF Insert Sequence:

ATGCTGTTTA AGAAGAACCT ATTTGAGATG GCGATTAACC TTGCCAAGAG CCAGCATCTG 
GACAGTGATG GGCTGGCCCA GATTTTCATG CAGTATGGAG ACCATCTCTA CAGCAAGGGC 
AACCACGATG GGGCTGTCCA GCAATATATC CGAACCATTG GAAAGTTGGA GCCATCCTAC 
GTGATCCGCA AGTTTCTGGA TGCCCAGCGC ATTCACAACC TGACTGCCTA CCTGCAGACC 
CTGCACCGAC AATCCCTGGC CAATGCCGAC CATACCACCC TGCTCCTCAA CTGCTATACC 
AAGCTCAAGG ACAGCTCGAA GCTGGAGGAG TTCATCAAGA AAAAGAGTGA GAGTGAAGTC 
CACTTTGATG TGGAGACAGC CATCAAGGTC CTCCGGCAGG CTGGCTACTA CTCCCATGCC 
CTGTATCTGG CGGAGAACCA TGCACATCAT GAGTGGTACC TGAAGATCCA GCTAGAAGAC 
ATTAAGAATT ATCAGGAAGC CCTTCGATAC ATCGGCAAGC TGCCTTTTGA GCAGGCAGAG 
AGCAACATGA AGCGCTACGG CAAGATCCTC ATGCACCACA TACCAGAGCA GACAACTCAG 
TTGCTGAAGG GACTTTGTAC TGATTATCGG CCCAGCCTCG AAGGCCGCAG CGATAGGGAG 
GCCCCAGGCT GCAGGGCCAA CTCTGAGGAG TTCATCCCCA TCTTTGCCAA TAACCCGCGA 
GAGCTGAAAG CCTTCCTAGA GCACATGAGT GAAGTGCAGC CAGACTCACC CCAGGGGATC 
TACGACACAC TCCTTGAGCT GCGACTGCAG AACTGGGCCC ACGAGAAGGA TCCACAGGTC 
AAAGAGAAGC TTCACGCAGA GGCCATTTCC CTGCTGAAGA GTGGTCGCTT CTGCGACGTC 
TTTGACAAGG CCCTGGTCCT GTGCCAGATG CACGACTTCC AGGATGGTGT CCTTTACCTT 
TATGAGCAGG GGAAGCTGTT CCAGCAGATC ATGCACTACC ACATGCAGCA CGAGCAGTAC 
CGGCAGGTCA TCAGCGTGTG TGAGCGCCAT GGGGAGCAGG ACCCCTCCTT GTGGGAGCAG 
GCCCTCAGCT ACTTCGCTCG CAAGGAGGAG GACTGCAAGG AGTATGTGGC AGCTGTCCTC 
AAGCATATCG AGAACAAGAA CCTCATGCCA CCTCTTCTAG TGGTGCAGAC CCTGGCCCAC 
AACTCCACAG CCACACTCTC CGTCATCAGG GACTACCTGG TCCAAAAACT ACAGAAACAG 
AGCCAGCAGA TTGCACAGGA TGAGCTGCGG GTGCGGCGGT ACCGAGAGGA GACCACCCGT 
ATCCGCCAGG AGATCCAAGA GCTCAAGGCC AGTCCTAAGA TTTTCCAAAA GACCAAGTGC 
AGCATCTGTA ACAGTGCCTT GGAGTTGCCC TCAGTCCACT TCCTGTGTGG CCACTCCTTC 
CACCAACACT GCTTTGAGAG TTACTCGGAA AGTGATGCTG ACTGCCCCAC CTGCCTCCCT 
GAAAACCGGA AGGTCATGGA TATGATCCGG GCCCAGGAAC AGAAACGAGA TCTCCATGAT 
CAATTCCAGC ATCAGCTCAA GTGCTCCAAT GACAGCTTTT CTGTGATTGC TGACTACTTT 
GGCAGAGGTG TTTTCAACAA ATTGACTCTG CTGACCGACC CTCCCACAGC CAGACTGACC 
TCCAGCCTGG AGGCTGGGCT GCAACGCGAC CTACTCATGC ACTCCAGGAG GGGCACTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

VPS11 ( XM_024448607.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024304375.1 Homo sapiens VPS11 core subunit of CORVET and HOPS complexes (VPS11), transcript variant X4, mRNA.

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CloneID	OHu106689
Clone ID Related Accession (Same CDS sequence)	XM_024448607.1
Accession Version	XM_024448607.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1416bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	vacuolar protein sorting-associated protein 11 homolog isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCTCCCT GGCAGAAAAA GAGTGAGAGT GAAGTCCACT TTGATGTGGA GACAGCCATC 
AAGGTCCTCC GGCAGGCTGG CTACTACTCC CATGCCCTGT ATCTGGCGGA GAACCATGCA 
CATCATGAGT GGTACCTGAA GATCCAGCTA GAAGACATTA AGAATTATCA GGAAGCCCTT 
CGATACATCG GCAAGCTGCC TTTTGAGCAG GCAGAGAGCA ACATGAAGCG CTACGGCAAG 
ATCCTCATGC ACCACATACC AGAGCAGACA ACTCAGTTGC TGAAGGGACT TTGTACTGAT 
TATCGGCCCA GCCTCGAAGG CCGCAGCGAT AGGGAGGCCC CAGGCTGCAG GGCCAACTCT 
GAGGAGTTCA TCCCCATCTT TGCCAATAAC CCGCGAGAGC TGAAAGCCTT CCTAGAGCAC 
ATGAGTGAAG TGCAGCCAGA CTCACCCCAG GGGATCTACG ACACACTCCT TGAGCTGCGA 
CTGCAGAACT GGGCCCACGA GAAGGATCCA CAGGTCAAAG AGAAGCTTCA CGCAGAGGCC 
ATTTCCCTGC TGAAGAGTGG TCGCTTCTGC GACGTCTTTG ACAAGGCCCT GGTCCTGTGC 
CAGATGCACG ACTTCCAGGA TGGTGTCCTT TACCTTTATG AGCAGGGGAA GCTGTTCCAG 
CAGATCATGC ACTACCACAT GCAGCACGAG CAGTACCGGC AGGTCATCAG CGTGTGTGAG 
CGCCATGGGG AGCAGGACCC CTCCTTGTGG GAGCAGGCCC TCAGCTACTT CGCTCGCAAG 
GAGGAGGACT GCAAGGAGTA TGTGGCAGCT GTCCTCAAGC ATATCGAGAA CAAGAACCTC 
ATGCCACCTC TTCTAGTGGT GCAGACCCTG GCCCACAACT CCACAGCCAC ACTCTCCGTC 
ATCAGGGACT ACCTGGTCCA AAAACTACAG AAACAGAGCC AGCAGATTGC ACAGGATGAG 
CTGCGGGTGC GGCGGTACCG AGAGGAGACC ACCCGTATCC GCCAGGAGAT CCAAGAGCTC 
AAGGCCAGTC CTAAGATTTT CCAAAAGACC AAGTGCAGCA TCTGTAACAG TGCCTTGGAG 
TTGCCCTCAG TCCACTTCCT GTGTGGCCAC TCCTTCCACC AACACTGCTT TGAGAGTTAC 
TCGGAAAGTG ATGCTGACTG CCCCACCTGC CTCCCTGAAA ACCGGAAGGT CATGGATATG 
ATCCGGGCCC AGGAACAGAA ACGAGATCTC CATGATCAAT TCCAGCATCA GCTCAAGTGC 
TCCAATGACA GCTTTTCTGT GATTGCTGAC TACTTTGGCA GAGGTGTTTT CAACAAATTG 
ACTCTGCTGA CCGACCCTCC CACAGCCAGA CTGACCTCCA GCCTGGAGGC TGGGCTGCAA 
CGCGACCTAC TCATGCACTC CAGGAGGGGC ACTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024304375.1
CDS	1506..2921
Translation	MSPWQKKSESEVHFDVETAIKVLRQAGYYSHALYLAENHAHHEWYLKIQLEDIKNYQEALRYIGKLPFEQAESNMKRYGKILMHHIPEQTTQLLKGLCTDYRPSLEGRSDREAPGCRANSEEFIPIFANNPRELKAFLEHMSEVQPDSPQGIYDTLLELRLQNWAHEKDPQVKEKLHAEAISLLKSGRFCDVFDKALVLCQMHDFQDGVLYLYEQGKLFQQIMHYHMQHEQYRQVISVCERHGEQDPSLWEQALSYFARKEEDCKEYVAAVLKHIENKNLMPPLLVVQTLAHNSTATLSVIRDYLVQKLQKQSQQIAQDELRVRRYREETTRIRQEIQELKASPKIFQKTKCSICNSALELPSVHFLCGHSFHQHCFESYSESDADCPTCLPENRKVMDMIRAQEQKRDLHDQFQHQLKCSNDSFSVIADYFGRGVFNKLTLLTDPPTARLTSSLEAGLQRDLLMHSRRGT

Target ORF information:

RefSeq Version	XM_024448607.1
Organism	Homo sapiens(human)
Definition	Homo sapiens VPS11 core subunit of CORVET and HOPS complexes (VPS11), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024448607.1

ORF Insert Sequence:

ATGTCTCCCT GGCAGAAAAA GAGTGAGAGT GAAGTCCACT TTGATGTGGA GACAGCCATC 
AAGGTCCTCC GGCAGGCTGG CTACTACTCC CATGCCCTGT ATCTGGCGGA GAACCATGCA 
CATCATGAGT GGTACCTGAA GATCCAGCTA GAAGACATTA AGAATTATCA GGAAGCCCTT 
CGATACATCG GCAAGCTGCC TTTTGAGCAG GCAGAGAGCA ACATGAAGCG CTACGGCAAG 
ATCCTCATGC ACCACATACC AGAGCAGACA ACTCAGTTGC TGAAGGGACT TTGTACTGAT 
TATCGGCCCA GCCTCGAAGG CCGCAGCGAT AGGGAGGCCC CAGGCTGCAG GGCCAACTCT 
GAGGAGTTCA TCCCCATCTT TGCCAATAAC CCGCGAGAGC TGAAAGCCTT CCTAGAGCAC 
ATGAGTGAAG TGCAGCCAGA CTCACCCCAG GGGATCTACG ACACACTCCT TGAGCTGCGA 
CTGCAGAACT GGGCCCACGA GAAGGATCCA CAGGTCAAAG AGAAGCTTCA CGCAGAGGCC 
ATTTCCCTGC TGAAGAGTGG TCGCTTCTGC GACGTCTTTG ACAAGGCCCT GGTCCTGTGC 
CAGATGCACG ACTTCCAGGA TGGTGTCCTT TACCTTTATG AGCAGGGGAA GCTGTTCCAG 
CAGATCATGC ACTACCACAT GCAGCACGAG CAGTACCGGC AGGTCATCAG CGTGTGTGAG 
CGCCATGGGG AGCAGGACCC CTCCTTGTGG GAGCAGGCCC TCAGCTACTT CGCTCGCAAG 
GAGGAGGACT GCAAGGAGTA TGTGGCAGCT GTCCTCAAGC ATATCGAGAA CAAGAACCTC 
ATGCCACCTC TTCTAGTGGT GCAGACCCTG GCCCACAACT CCACAGCCAC ACTCTCCGTC 
ATCAGGGACT ACCTGGTCCA AAAACTACAG AAACAGAGCC AGCAGATTGC ACAGGATGAG 
CTGCGGGTGC GGCGGTACCG AGAGGAGACC ACCCGTATCC GCCAGGAGAT CCAAGAGCTC 
AAGGCCAGTC CTAAGATTTT CCAAAAGACC AAGTGCAGCA TCTGTAACAG TGCCTTGGAG 
TTGCCCTCAG TCCACTTCCT GTGTGGCCAC TCCTTCCACC AACACTGCTT TGAGAGTTAC 
TCGGAAAGTG ATGCTGACTG CCCCACCTGC CTCCCTGAAA ACCGGAAGGT CATGGATATG 
ATCCGGGCCC AGGAACAGAA ACGAGATCTC CATGATCAAT TCCAGCATCA GCTCAAGTGC 
TCCAATGACA GCTTTTCTGT GATTGCTGAC TACTTTGGCA GAGGTGTTTT CAACAAATTG 
ACTCTGCTGA CCGACCCTCC CACAGCCAGA CTGACCTCCA GCCTGGAGGC TGGGCTGCAA 
CGCGACCTAC TCATGCACTC CAGGAGGGGC ACTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

VPS11 ( NM_001290185.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001277114.1 Homo sapiens VPS11 core subunit of CORVET and HOPS complexes (VPS11), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu28242
Clone ID Related Accession (Same CDS sequence)	NM_001290185.2 , NM_001290185.1
Accession Version	NM_001290185.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2796bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-10
Organism	Homo sapiens(human)
Product	vacuolar protein sorting-associated protein 11 homolog isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI561271.1, AK302973.1 and BC065563.1. On Jun 2, 2019 this sequence version replaced NM_001290185.1. Transcript Variant: This variant (2) differs in its 5' UTR and 5' coding region, and uses an alternate start codon, compared to variant 1. The encoded isoform (2) has a shorter and distinct N-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK302973.1, SRR1660807.118575.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAATCTG TTTGTCGGAG GGGTCCGTGC CGCGCGCCTC TTTGGTTTAG CTGGTCATCC 
AGAGTTGTTC TGTGGTCTAC GGGAAGAAAG AAGGAAGTCC ATCTCCTAAC TTGTTATCAA 
CTGAGCAATC CTGGGAGGCT CCTTGACTAC CCTGCACATA TGGAAGGCCA GATCTGGTTC 
TTGCCACGTT CCCTACAGCT TACAGGCTTC CAAGCCTACA AACTACGGGT GACACACCTG 
TACCAACTGA AGCAGCACAA TATTCTGGCA TCTGTTGGAG AAGATGAAGA GGGCATCAAC 
CCCTTGGTTA AGATCTGGAA CCTGGAGAAG AGAGATGGTG GCAATCCACT CTGCACTCGA 
ATCTTCCCTG CTATTCCAGG AACAGAGCCA ACTGTTGTAT CTTGTTTGAC TGTCCATGAA 
AATCTCAACT TTATGGCCAT TGGTTTCACA GATGGCAGTG TTACATTGAA CAAAGGAGAC 
ATCACCCGGG ACCGGCATAG CAAGACCCAG ATTTTGCACA AGGGCAACTA TCCTGTAACT 
GGATTGGCCT TTCGCCAAGC AGGAAAGACC ACTCACTTGT TTGTTGTGAC AACAGAGAAC 
GTCCAGTCCT ATATAGTTTC TGGAAAAGAC TACCCTCGCG TGGAGTTGGA CACCCATGGT 
TGTGGCCTGC GCTGCTCAGC CCTAAGTGAC CCTTCTCAGG ACCTGCAGTT CATTGTGGCC 
GGGGATGAGT GTGTCTACTT GTACCAGCCT GATGAACGTG GGCCCTGCTT CGCCTTTGAG 
GGCCATAAGC TCATTGCCCA CTGGTTTAGA GGCTACCTTA TCATTGTCTC CCGTGACCGG 
AAGGTTTCTC CCAAGTCAGA GTTTACCAGC AGGGATTCAC AGAGCTCCGA CAAGCAGATT 
CTAAACATCT ATGACCTGTG CAACAAGTTC ATAGCCTATA GCACCGTCTT TGAGGATGTA 
GTGGATGTGC TTGCTGAGTG GGGCTCCCTG TACGTGCTGA CGCGGGATGG GCGGGTCCAC 
GCACTGCAGG AGAAGGACAC ACAGACCAAA CTGGAGATGC TGTTTAAGAA GAACCTATTT 
GAGATGGCGA TTAACCTTGC CAAGAGCCAG CATCTGGACA GTGATGGGCT GGCCCAGATT 
TTCATGCAGT ATGGAGACCA TCTCTACAGC AAGGGCAACC ACGATGGGGC TGTCCAGCAA 
TATATCCGAA CCATTGGAAA GTTGGAGCCA TCCTACGTGA TCCGCAAGTT TCTGGATGCC 
CAGCGCATTC ACAACCTGAC TGCCTACCTG CAGACCCTGC ACCGACAATC CCTGGCCAAT 
GCCGACCATA CCACCCTGCT CCTCAACTGC TATACCAAGC TCAAGGACAG CTCGAAGCTG 
GAGGAGTTCA TCAAGAAAAA GAGTGAGAGT GAAGTCCACT TTGATGTGGA GACAGCCATC 
AAGGTCCTCC GGCAGGCTGG CTACTACTCC CATGCCCTGT ATCTGGCGGA GAACCATGCA 
CATCATGAGT GGTACCTGAA GATCCAGCTA GAAGACATTA AGAATTATCA GGAAGCCCTT 
CGATACATCG GCAAGCTGCC TTTTGAGCAG GCAGAGAGCA ACATGAAGCG CTACGGCAAG 
ATCCTCATGC ACCACATACC AGAGCAGACA ACTCAGTTGC TGAAGGGACT TTGTACTGAT 
TATCGGCCCA GCCTCGAAGG CCGCAGCGAT AGGGAGGCCC CAGGCTGCAG GGCCAACTCT 
GAGGAGTTCA TCCCCATCTT TGCCAATAAC CCGCGAGAGC TGAAAGCCTT CCTAGAGCAC 
ATGAGTGAAG TGCAGCCAGA CTCACCCCAG GGGATCTACG ACACACTCCT TGAGCTGCGA 
CTGCAGAACT GGGCCCACGA GAAGGATCCA CAGGTCAAAG AGAAGCTTCA CGCAGAGGCC 
ATTTCCCTGC TGAAGAGTGG TCGCTTCTGC GACGTCTTTG ACAAGGCCCT GGTCCTGTGC 
CAGATGCACG ACTTCCAGGA TGGTGTCCTT TACCTTTATG AGCAGGGGAA GCTGTTCCAG 
CAGATCATGC ACTACCACAT GCAGCACGAG CAGTACCGGC AGGTCATCAG CGTGTGTGAG 
CGCCATGGGG AGCAGGACCC CTCCTTGTGG GAGCAGGCCC TCAGCTACTT CGCTCGCAAG 
GAGGAGGACT GCAAGGAGTA TGTGGCAGCT GTCCTCAAGC ATATCGAGAA CAAGAACCTC 
ATGCCACCTC TTCTAGTGGT GCAGACCCTG GCCCACAACT CCACAGCCAC ACTCTCCGTC 
ATCAGGGACT ACCTGGTCCA AAAACTACAG AAACAGAGCC AGCAGATTGC ACAGGATGAG 
CTGCGGGTGC GGCGGTACCG AGAGGAGACC ACCCGTATCC GCCAGGAGAT CCAAGAGCTC 
AAGGCCAGTC CTAAGATTTT CCAAAAGACC AAGTGCAGCA TCTGTAACAG TGCCTTGGAG 
TTGCCCTCAG TCCACTTCCT GTGTGGCCAC TCCTTCCACC AACACTGCTT TGAGAGTTAC 
TCGGAAAGTG ATGCTGACTG CCCCACCTGC CTCCCTGAAA ACCGGAAGGT CATGGATATG 
ATCCGGGCCC AGGAACAGAA ACGAGATCTC CATGATCAAT TCCAGCATCA GCTCAAGTGC 
TCCAATGACA GCTTTTCTGT GATTGCTGAC TACTTTGGCA GAGGTGTTTT CAACAAATTG 
ACTCTGCTGA CCGACCCTCC CACAGCCAGA CTGACCTCCA GCCTGGAGGC TGGGCTGCAA 
CGCGACCTAC TCATGCACTC CAGGAGGGGC ACTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001277114.1
CDS	252..3047
Translation	MKSVCRRGPCRAPLWFSWSSRVVLWSTGRKKEVHLLTCYQLSNPGRLLDYPAHMEGQIWFLPRSLQLTGFQAYKLRVTHLYQLKQHNILASVGEDEEGINPLVKIWNLEKRDGGNPLCTRIFPAIPGTEPTVVSCLTVHENLNFMAIGFTDGSVTLNKGDITRDRHSKTQILHKGNYPVTGLAFRQAGKTTHLFVVTTENVQSYIVSGKDYPRVELDTHGCGLRCSALSDPSQDLQFIVAGDECVYLYQPDERGPCFAFEGHKLIAHWFRGYLIIVSRDRKVSPKSEFTSRDSQSSDKQILNIYDLCNKFIAYSTVFEDVVDVLAEWGSLYVLTRDGRVHALQEKDTQTKLEMLFKKNLFEMAINLAKSQHLDSDGLAQIFMQYGDHLYSKGNHDGAVQQYIRTIGKLEPSYVIRKFLDAQRIHNLTAYLQTLHRQSLANADHTTLLLNCYTKLKDSSKLEEFIKKKSESEVHFDVETAIKVLRQAGYYSHALYLAENHAHHEWYLKIQLEDIKNYQEALRYIGKLPFEQAESNMKRYGKILMHHIPEQTTQLLKGLCTDYRPSLEGRSDREAPGCRANSEEFIPIFANNPRELKAFLEHMSEVQPDSPQGIYDTLLELRLQNWAHEKDPQVKEKLHAEAISLLKSGRFCDVFDKALVLCQMHDFQDGVLYLYEQGKLFQQIMHYHMQHEQYRQVISVCERHGEQDPSLWEQALSYFARKEEDCKEYVAAVLKHIENKNLMPPLLVVQTLAHNSTATLSVIRDYLVQKLQKQSQQIAQDELRVRRYREETTRIRQEIQELKASPKIFQKTKCSICNSALELPSVHFLCGHSFHQHCFESYSESDADCPTCLPENRKVMDMIRAQEQKRDLHDQFQHQLKCSNDSFSVIADYFGRGVFNKLTLLTDPPTARLTSSLEAGLQRDLLMHSRRGT

Target ORF information:

RefSeq Version	NM_001290185.2
Organism	Homo sapiens(human)
Definition	Homo sapiens VPS11 core subunit of CORVET and HOPS complexes (VPS11), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001290185.2

ORF Insert Sequence:

ATGAAATCTG TTTGTCGGAG GGGTCCGTGC CGCGCGCCTC TTTGGTTTAG CTGGTCATCC 
AGAGTTGTTC TGTGGTCTAC GGGAAGAAAG AAGGAAGTCC ATCTCCTAAC TTGTTATCAA 
CTGAGCAATC CTGGGAGGCT CCTTGACTAC CCTGCACATA TGGAAGGCCA GATCTGGTTC 
TTGCCACGTT CCCTACAGCT TACAGGCTTC CAAGCCTACA AACTACGGGT GACACACCTG 
TACCAACTGA AGCAGCACAA TATTCTGGCA TCTGTTGGAG AAGATGAAGA GGGCATCAAC 
CCCTTGGTTA AGATCTGGAA CCTGGAGAAG AGAGATGGTG GCAATCCACT CTGCACTCGA 
ATCTTCCCTG CTATTCCAGG AACAGAGCCA ACTGTTGTAT CTTGTTTGAC TGTCCATGAA 
AATCTCAACT TTATGGCCAT TGGTTTCACA GATGGCAGTG TTACATTGAA CAAAGGAGAC 
ATCACCCGGG ACCGGCATAG CAAGACCCAG ATTTTGCACA AGGGCAACTA TCCTGTAACT 
GGATTGGCCT TTCGCCAAGC AGGAAAGACC ACTCACTTGT TTGTTGTGAC AACAGAGAAC 
GTCCAGTCCT ATATAGTTTC TGGAAAAGAC TACCCTCGCG TGGAGTTGGA CACCCATGGT 
TGTGGCCTGC GCTGCTCAGC CCTAAGTGAC CCTTCTCAGG ACCTGCAGTT CATTGTGGCC 
GGGGATGAGT GTGTCTACTT GTACCAGCCT GATGAACGTG GGCCCTGCTT CGCCTTTGAG 
GGCCATAAGC TCATTGCCCA CTGGTTTAGA GGCTACCTTA TCATTGTCTC CCGTGACCGG 
AAGGTTTCTC CCAAGTCAGA GTTTACCAGC AGGGATTCAC AGAGCTCCGA CAAGCAGATT 
CTAAACATCT ATGACCTGTG CAACAAGTTC ATAGCCTATA GCACCGTCTT TGAGGATGTA 
GTGGATGTGC TTGCTGAGTG GGGCTCCCTG TACGTGCTGA CGCGGGATGG GCGGGTCCAC 
GCACTGCAGG AGAAGGACAC ACAGACCAAA CTGGAGATGC TGTTTAAGAA GAACCTATTT 
GAGATGGCGA TTAACCTTGC CAAGAGCCAG CATCTGGACA GTGATGGGCT GGCCCAGATT 
TTCATGCAGT ATGGAGACCA TCTCTACAGC AAGGGCAACC ACGATGGGGC TGTCCAGCAA 
TATATCCGAA CCATTGGAAA GTTGGAGCCA TCCTACGTGA TCCGCAAGTT TCTGGATGCC 
CAGCGCATTC ACAACCTGAC TGCCTACCTG CAGACCCTGC ACCGACAATC CCTGGCCAAT 
GCCGACCATA CCACCCTGCT CCTCAACTGC TATACCAAGC TCAAGGACAG CTCGAAGCTG 
GAGGAGTTCA TCAAGAAAAA GAGTGAGAGT GAAGTCCACT TTGATGTGGA GACAGCCATC 
AAGGTCCTCC GGCAGGCTGG CTACTACTCC CATGCCCTGT ATCTGGCGGA GAACCATGCA 
CATCATGAGT GGTACCTGAA GATCCAGCTA GAAGACATTA AGAATTATCA GGAAGCCCTT 
CGATACATCG GCAAGCTGCC TTTTGAGCAG GCAGAGAGCA ACATGAAGCG CTACGGCAAG 
ATCCTCATGC ACCACATACC AGAGCAGACA ACTCAGTTGC TGAAGGGACT TTGTACTGAT 
TATCGGCCCA GCCTCGAAGG CCGCAGCGAT AGGGAGGCCC CAGGCTGCAG GGCCAACTCT 
GAGGAGTTCA TCCCCATCTT TGCCAATAAC CCGCGAGAGC TGAAAGCCTT CCTAGAGCAC 
ATGAGTGAAG TGCAGCCAGA CTCACCCCAG GGGATCTACG ACACACTCCT TGAGCTGCGA 
CTGCAGAACT GGGCCCACGA GAAGGATCCA CAGGTCAAAG AGAAGCTTCA CGCAGAGGCC 
ATTTCCCTGC TGAAGAGTGG TCGCTTCTGC GACGTCTTTG ACAAGGCCCT GGTCCTGTGC 
CAGATGCACG ACTTCCAGGA TGGTGTCCTT TACCTTTATG AGCAGGGGAA GCTGTTCCAG 
CAGATCATGC ACTACCACAT GCAGCACGAG CAGTACCGGC AGGTCATCAG CGTGTGTGAG 
CGCCATGGGG AGCAGGACCC CTCCTTGTGG GAGCAGGCCC TCAGCTACTT CGCTCGCAAG 
GAGGAGGACT GCAAGGAGTA TGTGGCAGCT GTCCTCAAGC ATATCGAGAA CAAGAACCTC 
ATGCCACCTC TTCTAGTGGT GCAGACCCTG GCCCACAACT CCACAGCCAC ACTCTCCGTC 
ATCAGGGACT ACCTGGTCCA AAAACTACAG AAACAGAGCC AGCAGATTGC ACAGGATGAG 
CTGCGGGTGC GGCGGTACCG AGAGGAGACC ACCCGTATCC GCCAGGAGAT CCAAGAGCTC 
AAGGCCAGTC CTAAGATTTT CCAAAAGACC AAGTGCAGCA TCTGTAACAG TGCCTTGGAG 
TTGCCCTCAG TCCACTTCCT GTGTGGCCAC TCCTTCCACC AACACTGCTT TGAGAGTTAC 
TCGGAAAGTG ATGCTGACTG CCCCACCTGC CTCCCTGAAA ACCGGAAGGT CATGGATATG 
ATCCGGGCCC AGGAACAGAA ACGAGATCTC CATGATCAAT TCCAGCATCA GCTCAAGTGC 
TCCAATGACA GCTTTTCTGT GATTGCTGAC TACTTTGGCA GAGGTGTTTT CAACAAATTG 
ACTCTGCTGA CCGACCCTCC CACAGCCAGA CTGACCTCCA GCCTGGAGGC TGGGCTGCAA 
CGCGACCTAC TCATGCACTC CAGGAGGGGC ACTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

VPS11 ( NM_001290185.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001277114.1 Homo sapiens VPS11 core subunit of CORVET and HOPS complexes (VPS11), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu28242
Clone ID Related Accession (Same CDS sequence)	NM_001290185.2 , NM_001290185.1
Accession Version	NM_001290185.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2796bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-01-27
Organism	Homo sapiens(human)
Product	vacuolar protein sorting-associated protein 11 homolog isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI561271.1, AK302973.1 and BC065563.1. Transcript Variant: This variant (2) differs in its 5' UTR and 5' coding region, and uses an alternate start codon, compared to variant 1. The encoded isoform (2) has a shorter and distinct N-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.16761.1, SRR1803615.162525.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAATCTG TTTGTCGGAG GGGTCCGTGC CGCGCGCCTC TTTGGTTTAG CTGGTCATCC 
AGAGTTGTTC TGTGGTCTAC GGGAAGAAAG AAGGAAGTCC ATCTCCTAAC TTGTTATCAA 
CTGAGCAATC CTGGGAGGCT CCTTGACTAC CCTGCACATA TGGAAGGCCA GATCTGGTTC 
TTGCCACGTT CCCTACAGCT TACAGGCTTC CAAGCCTACA AACTACGGGT GACACACCTG 
TACCAACTGA AGCAGCACAA TATTCTGGCA TCTGTTGGAG AAGATGAAGA GGGCATCAAC 
CCCTTGGTTA AGATCTGGAA CCTGGAGAAG AGAGATGGTG GCAATCCACT CTGCACTCGA 
ATCTTCCCTG CTATTCCAGG AACAGAGCCA ACTGTTGTAT CTTGTTTGAC TGTCCATGAA 
AATCTCAACT TTATGGCCAT TGGTTTCACA GATGGCAGTG TTACATTGAA CAAAGGAGAC 
ATCACCCGGG ACCGGCATAG CAAGACCCAG ATTTTGCACA AGGGCAACTA TCCTGTAACT 
GGATTGGCCT TTCGCCAAGC AGGAAAGACC ACTCACTTGT TTGTTGTGAC AACAGAGAAC 
GTCCAGTCCT ATATAGTTTC TGGAAAAGAC TACCCTCGCG TGGAGTTGGA CACCCATGGT 
TGTGGCCTGC GCTGCTCAGC CCTAAGTGAC CCTTCTCAGG ACCTGCAGTT CATTGTGGCC 
GGGGATGAGT GTGTCTACTT GTACCAGCCT GATGAACGTG GGCCCTGCTT CGCCTTTGAG 
GGCCATAAGC TCATTGCCCA CTGGTTTAGA GGCTACCTTA TCATTGTCTC CCGTGACCGG 
AAGGTTTCTC CCAAGTCAGA GTTTACCAGC AGGGATTCAC AGAGCTCCGA CAAGCAGATT 
CTAAACATCT ATGACCTGTG CAACAAGTTC ATAGCCTATA GCACCGTCTT TGAGGATGTA 
GTGGATGTGC TTGCTGAGTG GGGCTCCCTG TACGTGCTGA CGCGGGATGG GCGGGTCCAC 
GCACTGCAGG AGAAGGACAC ACAGACCAAA CTGGAGATGC TGTTTAAGAA GAACCTATTT 
GAGATGGCGA TTAACCTTGC CAAGAGCCAG CATCTGGACA GTGATGGGCT GGCCCAGATT 
TTCATGCAGT ATGGAGACCA TCTCTACAGC AAGGGCAACC ACGATGGGGC TGTCCAGCAA 
TATATCCGAA CCATTGGAAA GTTGGAGCCA TCCTACGTGA TCCGCAAGTT TCTGGATGCC 
CAGCGCATTC ACAACCTGAC TGCCTACCTG CAGACCCTGC ACCGACAATC CCTGGCCAAT 
GCCGACCATA CCACCCTGCT CCTCAACTGC TATACCAAGC TCAAGGACAG CTCGAAGCTG 
GAGGAGTTCA TCAAGAAAAA GAGTGAGAGT GAAGTCCACT TTGATGTGGA GACAGCCATC 
AAGGTCCTCC GGCAGGCTGG CTACTACTCC CATGCCCTGT ATCTGGCGGA GAACCATGCA 
CATCATGAGT GGTACCTGAA GATCCAGCTA GAAGACATTA AGAATTATCA GGAAGCCCTT 
CGATACATCG GCAAGCTGCC TTTTGAGCAG GCAGAGAGCA ACATGAAGCG CTACGGCAAG 
ATCCTCATGC ACCACATACC AGAGCAGACA ACTCAGTTGC TGAAGGGACT TTGTACTGAT 
TATCGGCCCA GCCTCGAAGG CCGCAGCGAT AGGGAGGCCC CAGGCTGCAG GGCCAACTCT 
GAGGAGTTCA TCCCCATCTT TGCCAATAAC CCGCGAGAGC TGAAAGCCTT CCTAGAGCAC 
ATGAGTGAAG TGCAGCCAGA CTCACCCCAG GGGATCTACG ACACACTCCT TGAGCTGCGA 
CTGCAGAACT GGGCCCACGA GAAGGATCCA CAGGTCAAAG AGAAGCTTCA CGCAGAGGCC 
ATTTCCCTGC TGAAGAGTGG TCGCTTCTGC GACGTCTTTG ACAAGGCCCT GGTCCTGTGC 
CAGATGCACG ACTTCCAGGA TGGTGTCCTT TACCTTTATG AGCAGGGGAA GCTGTTCCAG 
CAGATCATGC ACTACCACAT GCAGCACGAG CAGTACCGGC AGGTCATCAG CGTGTGTGAG 
CGCCATGGGG AGCAGGACCC CTCCTTGTGG GAGCAGGCCC TCAGCTACTT CGCTCGCAAG 
GAGGAGGACT GCAAGGAGTA TGTGGCAGCT GTCCTCAAGC ATATCGAGAA CAAGAACCTC 
ATGCCACCTC TTCTAGTGGT GCAGACCCTG GCCCACAACT CCACAGCCAC ACTCTCCGTC 
ATCAGGGACT ACCTGGTCCA AAAACTACAG AAACAGAGCC AGCAGATTGC ACAGGATGAG 
CTGCGGGTGC GGCGGTACCG AGAGGAGACC ACCCGTATCC GCCAGGAGAT CCAAGAGCTC 
AAGGCCAGTC CTAAGATTTT CCAAAAGACC AAGTGCAGCA TCTGTAACAG TGCCTTGGAG 
TTGCCCTCAG TCCACTTCCT GTGTGGCCAC TCCTTCCACC AACACTGCTT TGAGAGTTAC 
TCGGAAAGTG ATGCTGACTG CCCCACCTGC CTCCCTGAAA ACCGGAAGGT CATGGATATG 
ATCCGGGCCC AGGAACAGAA ACGAGATCTC CATGATCAAT TCCAGCATCA GCTCAAGTGC 
TCCAATGACA GCTTTTCTGT GATTGCTGAC TACTTTGGCA GAGGTGTTTT CAACAAATTG 
ACTCTGCTGA CCGACCCTCC CACAGCCAGA CTGACCTCCA GCCTGGAGGC TGGGCTGCAA 
CGCGACCTAC TCATGCACTC CAGGAGGGGC ACTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001277114.1
CDS	318..3113
Translation	MKSVCRRGPCRAPLWFSWSSRVVLWSTGRKKEVHLLTCYQLSNPGRLLDYPAHMEGQIWFLPRSLQLTGFQAYKLRVTHLYQLKQHNILASVGEDEEGINPLVKIWNLEKRDGGNPLCTRIFPAIPGTEPTVVSCLTVHENLNFMAIGFTDGSVTLNKGDITRDRHSKTQILHKGNYPVTGLAFRQAGKTTHLFVVTTENVQSYIVSGKDYPRVELDTHGCGLRCSALSDPSQDLQFIVAGDECVYLYQPDERGPCFAFEGHKLIAHWFRGYLIIVSRDRKVSPKSEFTSRDSQSSDKQILNIYDLCNKFIAYSTVFEDVVDVLAEWGSLYVLTRDGRVHALQEKDTQTKLEMLFKKNLFEMAINLAKSQHLDSDGLAQIFMQYGDHLYSKGNHDGAVQQYIRTIGKLEPSYVIRKFLDAQRIHNLTAYLQTLHRQSLANADHTTLLLNCYTKLKDSSKLEEFIKKKSESEVHFDVETAIKVLRQAGYYSHALYLAENHAHHEWYLKIQLEDIKNYQEALRYIGKLPFEQAESNMKRYGKILMHHIPEQTTQLLKGLCTDYRPSLEGRSDREAPGCRANSEEFIPIFANNPRELKAFLEHMSEVQPDSPQGIYDTLLELRLQNWAHEKDPQVKEKLHAEAISLLKSGRFCDVFDKALVLCQMHDFQDGVLYLYEQGKLFQQIMHYHMQHEQYRQVISVCERHGEQDPSLWEQALSYFARKEEDCKEYVAAVLKHIENKNLMPPLLVVQTLAHNSTATLSVIRDYLVQKLQKQSQQIAQDELRVRRYREETTRIRQEIQELKASPKIFQKTKCSICNSALELPSVHFLCGHSFHQHCFESYSESDADCPTCLPENRKVMDMIRAQEQKRDLHDQFQHQLKCSNDSFSVIADYFGRGVFNKLTLLTDPPTARLTSSLEAGLQRDLLMHSRRGT

Target ORF information:

RefSeq Version	NM_001290185.1
Organism	Homo sapiens(human)
Definition	Homo sapiens VPS11 core subunit of CORVET and HOPS complexes (VPS11), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001290185.1

ORF Insert Sequence:

ATGAAATCTG TTTGTCGGAG GGGTCCGTGC CGCGCGCCTC TTTGGTTTAG CTGGTCATCC 
AGAGTTGTTC TGTGGTCTAC GGGAAGAAAG AAGGAAGTCC ATCTCCTAAC TTGTTATCAA 
CTGAGCAATC CTGGGAGGCT CCTTGACTAC CCTGCACATA TGGAAGGCCA GATCTGGTTC 
TTGCCACGTT CCCTACAGCT TACAGGCTTC CAAGCCTACA AACTACGGGT GACACACCTG 
TACCAACTGA AGCAGCACAA TATTCTGGCA TCTGTTGGAG AAGATGAAGA GGGCATCAAC 
CCCTTGGTTA AGATCTGGAA CCTGGAGAAG AGAGATGGTG GCAATCCACT CTGCACTCGA 
ATCTTCCCTG CTATTCCAGG AACAGAGCCA ACTGTTGTAT CTTGTTTGAC TGTCCATGAA 
AATCTCAACT TTATGGCCAT TGGTTTCACA GATGGCAGTG TTACATTGAA CAAAGGAGAC 
ATCACCCGGG ACCGGCATAG CAAGACCCAG ATTTTGCACA AGGGCAACTA TCCTGTAACT 
GGATTGGCCT TTCGCCAAGC AGGAAAGACC ACTCACTTGT TTGTTGTGAC AACAGAGAAC 
GTCCAGTCCT ATATAGTTTC TGGAAAAGAC TACCCTCGCG TGGAGTTGGA CACCCATGGT 
TGTGGCCTGC GCTGCTCAGC CCTAAGTGAC CCTTCTCAGG ACCTGCAGTT CATTGTGGCC 
GGGGATGAGT GTGTCTACTT GTACCAGCCT GATGAACGTG GGCCCTGCTT CGCCTTTGAG 
GGCCATAAGC TCATTGCCCA CTGGTTTAGA GGCTACCTTA TCATTGTCTC CCGTGACCGG 
AAGGTTTCTC CCAAGTCAGA GTTTACCAGC AGGGATTCAC AGAGCTCCGA CAAGCAGATT 
CTAAACATCT ATGACCTGTG CAACAAGTTC ATAGCCTATA GCACCGTCTT TGAGGATGTA 
GTGGATGTGC TTGCTGAGTG GGGCTCCCTG TACGTGCTGA CGCGGGATGG GCGGGTCCAC 
GCACTGCAGG AGAAGGACAC ACAGACCAAA CTGGAGATGC TGTTTAAGAA GAACCTATTT 
GAGATGGCGA TTAACCTTGC CAAGAGCCAG CATCTGGACA GTGATGGGCT GGCCCAGATT 
TTCATGCAGT ATGGAGACCA TCTCTACAGC AAGGGCAACC ACGATGGGGC TGTCCAGCAA 
TATATCCGAA CCATTGGAAA GTTGGAGCCA TCCTACGTGA TCCGCAAGTT TCTGGATGCC 
CAGCGCATTC ACAACCTGAC TGCCTACCTG CAGACCCTGC ACCGACAATC CCTGGCCAAT 
GCCGACCATA CCACCCTGCT CCTCAACTGC TATACCAAGC TCAAGGACAG CTCGAAGCTG 
GAGGAGTTCA TCAAGAAAAA GAGTGAGAGT GAAGTCCACT TTGATGTGGA GACAGCCATC 
AAGGTCCTCC GGCAGGCTGG CTACTACTCC CATGCCCTGT ATCTGGCGGA GAACCATGCA 
CATCATGAGT GGTACCTGAA GATCCAGCTA GAAGACATTA AGAATTATCA GGAAGCCCTT 
CGATACATCG GCAAGCTGCC TTTTGAGCAG GCAGAGAGCA ACATGAAGCG CTACGGCAAG 
ATCCTCATGC ACCACATACC AGAGCAGACA ACTCAGTTGC TGAAGGGACT TTGTACTGAT 
TATCGGCCCA GCCTCGAAGG CCGCAGCGAT AGGGAGGCCC CAGGCTGCAG GGCCAACTCT 
GAGGAGTTCA TCCCCATCTT TGCCAATAAC CCGCGAGAGC TGAAAGCCTT CCTAGAGCAC 
ATGAGTGAAG TGCAGCCAGA CTCACCCCAG GGGATCTACG ACACACTCCT TGAGCTGCGA 
CTGCAGAACT GGGCCCACGA GAAGGATCCA CAGGTCAAAG AGAAGCTTCA CGCAGAGGCC 
ATTTCCCTGC TGAAGAGTGG TCGCTTCTGC GACGTCTTTG ACAAGGCCCT GGTCCTGTGC 
CAGATGCACG ACTTCCAGGA TGGTGTCCTT TACCTTTATG AGCAGGGGAA GCTGTTCCAG 
CAGATCATGC ACTACCACAT GCAGCACGAG CAGTACCGGC AGGTCATCAG CGTGTGTGAG 
CGCCATGGGG AGCAGGACCC CTCCTTGTGG GAGCAGGCCC TCAGCTACTT CGCTCGCAAG 
GAGGAGGACT GCAAGGAGTA TGTGGCAGCT GTCCTCAAGC ATATCGAGAA CAAGAACCTC 
ATGCCACCTC TTCTAGTGGT GCAGACCCTG GCCCACAACT CCACAGCCAC ACTCTCCGTC 
ATCAGGGACT ACCTGGTCCA AAAACTACAG AAACAGAGCC AGCAGATTGC ACAGGATGAG 
CTGCGGGTGC GGCGGTACCG AGAGGAGACC ACCCGTATCC GCCAGGAGAT CCAAGAGCTC 
AAGGCCAGTC CTAAGATTTT CCAAAAGACC AAGTGCAGCA TCTGTAACAG TGCCTTGGAG 
TTGCCCTCAG TCCACTTCCT GTGTGGCCAC TCCTTCCACC AACACTGCTT TGAGAGTTAC 
TCGGAAAGTG ATGCTGACTG CCCCACCTGC CTCCCTGAAA ACCGGAAGGT CATGGATATG 
ATCCGGGCCC AGGAACAGAA ACGAGATCTC CATGATCAAT TCCAGCATCA GCTCAAGTGC 
TCCAATGACA GCTTTTCTGT GATTGCTGAC TACTTTGGCA GAGGTGTTTT CAACAAATTG 
ACTCTGCTGA CCGACCCTCC CACAGCCAGA CTGACCTCCA GCCTGGAGGC TGGGCTGCAA 
CGCGACCTAC TCATGCACTC CAGGAGGGGC ACTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

The second report of a new hypomyelinating disease due to a defect in the VPS11 gene discloses a massive lysosomal involvement.
Journal of inherited metabolic disease39(6)849-857(2016 Nov)
H?rtnagel K,Kr?geloh-Mann I,Bornemann A,D?cker M,Biskup S,Mayrhofer H,Battke F,du Bois G,Harzer K

A Founder Mutation in VPS11 Causes an Autosomal Recessive Leukoencephalopathy Linked to Autophagic Defects.
PLoS genetics12(4)e1005848(2016 Apr)
Zhang J,Lachance V,Schaffner A,Li X,Fedick A,Kaye LE,Liao J,Rosenfeld J,Yachelevich N,Chu ML,Mitchell WG,Boles RG,Moran E,Tokita M,Gorman E,Bagley K,Zhang W,Xia F,Leduc M,Yang Y,Eng C,Wong LJ,Schiffmann R,Diaz GA,Kornreich R,Thummel R,Wasserstein M,Yue Z,Edelmann L

A human interactome in three quantitative dimensions organized by stoichiometries and abundances.
Cell163(3)712-23(2015 Oct)
Hein MY,Hubner NC,Poser I,Cox J,Nagaraj N,Toyoda Y,Gak IA,Weisswange I,Mansfeld J,Buchholz F,Hyman AA,Mann M

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VPS11 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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