SCN3B cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SCN3B
Entrez Gene ID	55800
Full Name	sodium voltage-gated channel beta subunit 3
Synonyms	ATFB16,BRGDA7,HSA243396,SCNB3
General protein information	Preferred Names sodium voltage-gated channel beta subunit 3 Names sodium channel subunit beta-3 sodium channel, voltage-gated, type III, beta subunit voltage-gated sodium channel beta-3 subunit
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 11 Map Location: 11q24.1
Summary	Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel beta subunit gene family, and influences the inactivation kinetics of the sodium channel. Two alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008].
Disorder MIM:	608214
Disorder Html:	Brugada syndrome 7, 613120 (3); Atrial fibrillation, familial, 16, 613120 (3)

mRNA and Protein(s)

mRNA	Protein	Name
XM_011542897.2	XP_011541199.1	sodium channel subunit beta-3 isoform X1
XM_011542897.1	XP_011541199.1	sodium channel subunit beta-3 isoform X1
NM_018400.3	NP_060870.1	sodium channel subunit beta-3 precursor
NM_001040151.1	NP_001035241.1	sodium channel subunit beta-3 precursor

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Scn3b	NP_001077386.1
Danio rerio (zebrafish)	scn3b	NP_001074271.1
Homo sapiens (human)	SCN3B	NP_001035241.1
Pan troglodytes (chimpanzee)	SCN3B	XP_522210.3
Rattus norvegicus (Norway rat)	Scn3b	NP_620797.1
	SCN3B	XP_001104555.2
Canis lupus familiaris (dog)	SCN3B	XP_005619701.1
Gallus gallus (chicken)	SCN3B	XP_417884.4
Xenopus tropicalis (tropical clawed frog)	scn3b	NP_001011299.1
Bos taurus (cattle)	SCN3B	NP_001039960.1

Gene Ontology
Bibliography

Related articles in PubMed

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

The role of the sodium current complex in a nonreferred nationwide cohort of sudden infant death syndrome.
Winkel BG, Yuan L, Olesen MS, Sadjadieh G, Wang Y, Risgaard B, Jabbari R, Hauns? S, Holst AG, Hollegaard MV, Tfelt-Hansen J, Jespersen T
Heart rhythm12(6)1241-9(2015 Jun)

Contribution of Cardiac Sodium Channel ?-Subunit Variants to Brugada Syndrome.
Peeters U, Scornik F, Riur? H, P?rez G, Komurcu-Bayrak E, Van Malderen S, Pappaert G, Tarradas A, Pagans S, Daneels D, Breckpot K, Brugada P, Bonduelle M, Brugada R, Van Dooren S
Circulation journal : official journal of the Japanese Circulation Society79(10)2118-29(2015)

Risk factors and genetics of atrial fibrillation.
Anumonwo JM, Kalifa J
Cardiology clinics32(4)485-94(2014 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

In a nonreferred nationwide Danish cohort of SIDS cases, up to 5/66 (7.5%) of SIDS cases can be explained by genetic variants in the sodium channel complex genes.
Title: The role of the sodium current complex in a nonreferred nationwide cohort of sudden infant death syndrome.

Contribution of Cardiac Sodium Channel beta-Subunit Variants to Brugada Syndrome.
Title: Contribution of Cardiac Sodium Channel ?-Subunit Variants to Brugada Syndrome.

SCN1-3B the gene that encode respectively a- and b-subunits of the cardiac fast voltage-gated sodium channel, have been linked to atrial fibrillation.
Title: Risk factors and genetics of atrial fibrillation.

the beta3 subunit can mediate trans homophilic-binding via its Ig domain and the beta3-Ig domain can associate heterophilically with the beta1 subunit
Title: The immunoglobulin domain of the sodium channel ?3 subunit contains a surface-localized disulfide bond that is required for homophilic binding.

The Val110Ile mutation of SCN3B is a relatively common cause of SCN5A-negative BrS in Japan, which has a reduced sodium current because of the loss of cell surface expression of Nav1.5.
Title: Novel SCN3B mutation associated with brugada syndrome affects intracellular trafficking and function of Nav1.5.

The following SCN3B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SCN3B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu16302	NM_018400.3 Latest version!	Homo sapiens sodium voltage-gated channel beta subunit 3 (SCN3B), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu16302	NM_001040151.1 Latest version!	Homo sapiens sodium voltage-gated channel beta subunit 3 (SCN3B), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu16302	XM_011542897.2 Latest version!	Homo sapiens sodium voltage-gated channel beta subunit 3 (SCN3B), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
View Old Accession Versions >>
OHu16302	XM_011542897.1	Homo sapiens sodium voltage-gated channel beta subunit 3 (SCN3B), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SCN3B ( NM_018400.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_060870.1 Homo sapiens sodium voltage-gated channel beta subunit 3 (SCN3B), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu16302
Clone ID Related Accession (Same CDS sequence)	XM_011542897.2 , XM_011542897.1 , NM_018400.3 , NM_001040151.1
Accession Version	NM_018400.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 648bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-21
Organism	Homo sapiens(human)
Product	sodium channel subunit beta-3 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA327760.1, AL136589.1, DA806480.1, BP202832.1, AP002765.3 and BX106794.1. This sequence is a reference standard in the RefSeqGene project. On Apr 26, 2006 this sequence version replaced NM_018400.2. Transcript Variant: This variant (1) represents the longest transcript. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803616.140969.1, SRR1803616.209811.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2162841 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCCTGCCT TCAATAGATT GTTTCCCCTG GCTTCTCTCG TGCTTATCTA CTGGGTCAGT 
GTCTGCTTCC CTGTGTGTGT GGAAGTGCCC TCGGAGACGG AGGCCGTGCA GGGCAACCCC 
ATGAAGCTGC GCTGCATCTC CTGCATGAAG AGAGAGGAGG TGGAGGCCAC CACGGTGGTG 
GAATGGTTCT ACAGGCCCGA GGGCGGTAAA GATTTCCTTA TTTACGAGTA TCGGAATGGC 
CACCAGGAGG TGGAGAGCCC CTTTCAGGGG CGCCTGCAGT GGAATGGCAG CAAGGACCTG 
CAGGACGTGT CCATCACTGT GCTCAACGTC ACTCTGAACG ACTCTGGCCT CTACACCTGC 
AATGTGTCCC GGGAGTTTGA GTTTGAGGCG CATCGGCCCT TTGTGAAGAC GACGCGGCTG 
ATCCCCCTAA GAGTCACCGA GGAGGCTGGA GAGGACTTCA CCTCTGTGGT CTCAGAAATC 
ATGATGTACA TCCTTCTGGT CTTCCTCACC TTGTGGCTGC TCATCGAGAT GATATATTGC 
TACAGAAAGG TCTCAAAAGC CGAAGAGGCA GCCCAAGAAA ACGCGTCTGA CTACCTTGCC 
ATCCCATCTG AGAACAAGGA GAACTCTGCG GTACCAGTGG AGGAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060870.1
CDS	807..1454
Translation	MPAFNRLFPLASLVLIYWVSVCFPVCVEVPSETEAVQGNPMKLRCISCMKREEVEATTVVEWFYRPEGGKDFLIYEYRNGHQEVESPFQGRLQWNGSKDLQDVSITVLNVTLNDSGLYTCNVSREFEFEAHRPFVKTTRLIPLRVTEEAGEDFTSVVSEIMMYILLVFLTLWLLIEMIYCYRKVSKAEEAAQENASDYLAIPSENKENSAVPVEE

Target ORF information:

RefSeq Version	NM_018400.3
Organism	Homo sapiens(human)
Definition	Homo sapiens sodium voltage-gated channel beta subunit 3 (SCN3B), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018400.3

ORF Insert Sequence:

ATGCCTGCCT TCAATAGATT GTTTCCCCTG GCTTCTCTCG TGCTTATCTA CTGGGTCAGT 
GTCTGCTTCC CTGTGTGTGT GGAAGTGCCC TCGGAGACGG AGGCCGTGCA GGGCAACCCC 
ATGAAGCTGC GCTGCATCTC CTGCATGAAG AGAGAGGAGG TGGAGGCCAC CACGGTGGTG 
GAATGGTTCT ACAGGCCCGA GGGCGGTAAA GATTTCCTTA TTTACGAGTA TCGGAATGGC 
CACCAGGAGG TGGAGAGCCC CTTTCAGGGG CGCCTGCAGT GGAATGGCAG CAAGGACCTG 
CAGGACGTGT CCATCACTGT GCTCAACGTC ACTCTGAACG ACTCTGGCCT CTACACCTGC 
AATGTGTCCC GGGAGTTTGA GTTTGAGGCG CATCGGCCCT TTGTGAAGAC GACGCGGCTG 
ATCCCCCTAA GAGTCACCGA GGAGGCTGGA GAGGACTTCA CCTCTGTGGT CTCAGAAATC 
ATGATGTACA TCCTTCTGGT CTTCCTCACC TTGTGGCTGC TCATCGAGAT GATATATTGC 
TACAGAAAGG TCTCAAAAGC CGAAGAGGCA GCCCAAGAAA ACGCGTCTGA CTACCTTGCC 
ATCCCATCTG AGAACAAGGA GAACTCTGCG GTACCAGTGG AGGAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SCN3B ( NM_001040151.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001035241.1 Homo sapiens sodium voltage-gated channel beta subunit 3 (SCN3B), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu16302
Clone ID Related Accession (Same CDS sequence)	XM_011542897.2 , XM_011542897.1 , NM_018400.3 , NM_001040151.1
Accession Version	NM_001040151.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 648bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-21
Organism	Homo sapiens(human)
Product	sodium channel subunit beta-3 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA327760.1, AL136589.1, AP002765.3 and BX106794.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same isoform. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.14151.1, SRR1660809.251090.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2162841 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCTGCCT TCAATAGATT GTTTCCCCTG GCTTCTCTCG TGCTTATCTA CTGGGTCAGT 
GTCTGCTTCC CTGTGTGTGT GGAAGTGCCC TCGGAGACGG AGGCCGTGCA GGGCAACCCC 
ATGAAGCTGC GCTGCATCTC CTGCATGAAG AGAGAGGAGG TGGAGGCCAC CACGGTGGTG 
GAATGGTTCT ACAGGCCCGA GGGCGGTAAA GATTTCCTTA TTTACGAGTA TCGGAATGGC 
CACCAGGAGG TGGAGAGCCC CTTTCAGGGG CGCCTGCAGT GGAATGGCAG CAAGGACCTG 
CAGGACGTGT CCATCACTGT GCTCAACGTC ACTCTGAACG ACTCTGGCCT CTACACCTGC 
AATGTGTCCC GGGAGTTTGA GTTTGAGGCG CATCGGCCCT TTGTGAAGAC GACGCGGCTG 
ATCCCCCTAA GAGTCACCGA GGAGGCTGGA GAGGACTTCA CCTCTGTGGT CTCAGAAATC 
ATGATGTACA TCCTTCTGGT CTTCCTCACC TTGTGGCTGC TCATCGAGAT GATATATTGC 
TACAGAAAGG TCTCAAAAGC CGAAGAGGCA GCCCAAGAAA ACGCGTCTGA CTACCTTGCC 
ATCCCATCTG AGAACAAGGA GAACTCTGCG GTACCAGTGG AGGAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001035241.1
CDS	408..1055
Translation	MPAFNRLFPLASLVLIYWVSVCFPVCVEVPSETEAVQGNPMKLRCISCMKREEVEATTVVEWFYRPEGGKDFLIYEYRNGHQEVESPFQGRLQWNGSKDLQDVSITVLNVTLNDSGLYTCNVSREFEFEAHRPFVKTTRLIPLRVTEEAGEDFTSVVSEIMMYILLVFLTLWLLIEMIYCYRKVSKAEEAAQENASDYLAIPSENKENSAVPVEE

Target ORF information:

RefSeq Version	NM_001040151.1
Organism	Homo sapiens(human)
Definition	Homo sapiens sodium voltage-gated channel beta subunit 3 (SCN3B), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001040151.1

ORF Insert Sequence:

ATGCCTGCCT TCAATAGATT GTTTCCCCTG GCTTCTCTCG TGCTTATCTA CTGGGTCAGT 
GTCTGCTTCC CTGTGTGTGT GGAAGTGCCC TCGGAGACGG AGGCCGTGCA GGGCAACCCC 
ATGAAGCTGC GCTGCATCTC CTGCATGAAG AGAGAGGAGG TGGAGGCCAC CACGGTGGTG 
GAATGGTTCT ACAGGCCCGA GGGCGGTAAA GATTTCCTTA TTTACGAGTA TCGGAATGGC 
CACCAGGAGG TGGAGAGCCC CTTTCAGGGG CGCCTGCAGT GGAATGGCAG CAAGGACCTG 
CAGGACGTGT CCATCACTGT GCTCAACGTC ACTCTGAACG ACTCTGGCCT CTACACCTGC 
AATGTGTCCC GGGAGTTTGA GTTTGAGGCG CATCGGCCCT TTGTGAAGAC GACGCGGCTG 
ATCCCCCTAA GAGTCACCGA GGAGGCTGGA GAGGACTTCA CCTCTGTGGT CTCAGAAATC 
ATGATGTACA TCCTTCTGGT CTTCCTCACC TTGTGGCTGC TCATCGAGAT GATATATTGC 
TACAGAAAGG TCTCAAAAGC CGAAGAGGCA GCCCAAGAAA ACGCGTCTGA CTACCTTGCC 
ATCCCATCTG AGAACAAGGA GAACTCTGCG GTACCAGTGG AGGAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SCN3B ( XM_011542897.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011541199.1 Homo sapiens sodium voltage-gated channel beta subunit 3 (SCN3B), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu16302
Clone ID Related Accession (Same CDS sequence)	XM_011542897.2 , XM_011542897.1 , NM_018400.3 , NM_001040151.1
Accession Version	XM_011542897.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 648bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	sodium channel subunit beta-3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011542897.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCTGCCT TCAATAGATT GTTTCCCCTG GCTTCTCTCG TGCTTATCTA CTGGGTCAGT 
GTCTGCTTCC CTGTGTGTGT GGAAGTGCCC TCGGAGACGG AGGCCGTGCA GGGCAACCCC 
ATGAAGCTGC GCTGCATCTC CTGCATGAAG AGAGAGGAGG TGGAGGCCAC CACGGTGGTG 
GAATGGTTCT ACAGGCCCGA GGGCGGTAAA GATTTCCTTA TTTACGAGTA TCGGAATGGC 
CACCAGGAGG TGGAGAGCCC CTTTCAGGGG CGCCTGCAGT GGAATGGCAG CAAGGACCTG 
CAGGACGTGT CCATCACTGT GCTCAACGTC ACTCTGAACG ACTCTGGCCT CTACACCTGC 
AATGTGTCCC GGGAGTTTGA GTTTGAGGCG CATCGGCCCT TTGTGAAGAC GACGCGGCTG 
ATCCCCCTAA GAGTCACCGA GGAGGCTGGA GAGGACTTCA CCTCTGTGGT CTCAGAAATC 
ATGATGTACA TCCTTCTGGT CTTCCTCACC TTGTGGCTGC TCATCGAGAT GATATATTGC 
TACAGAAAGG TCTCAAAAGC CGAAGAGGCA GCCCAAGAAA ACGCGTCTGA CTACCTTGCC 
ATCCCATCTG AGAACAAGGA GAACTCTGCG GTACCAGTGG AGGAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011541199.1
CDS	404..1051
Translation	MPAFNRLFPLASLVLIYWVSVCFPVCVEVPSETEAVQGNPMKLRCISCMKREEVEATTVVEWFYRPEGGKDFLIYEYRNGHQEVESPFQGRLQWNGSKDLQDVSITVLNVTLNDSGLYTCNVSREFEFEAHRPFVKTTRLIPLRVTEEAGEDFTSVVSEIMMYILLVFLTLWLLIEMIYCYRKVSKAEEAAQENASDYLAIPSENKENSAVPVEE

Target ORF information:

RefSeq Version	XM_011542897.2
Organism	Homo sapiens(human)
Definition	Homo sapiens sodium voltage-gated channel beta subunit 3 (SCN3B), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011542897.2

ORF Insert Sequence:

ATGCCTGCCT TCAATAGATT GTTTCCCCTG GCTTCTCTCG TGCTTATCTA CTGGGTCAGT 
GTCTGCTTCC CTGTGTGTGT GGAAGTGCCC TCGGAGACGG AGGCCGTGCA GGGCAACCCC 
ATGAAGCTGC GCTGCATCTC CTGCATGAAG AGAGAGGAGG TGGAGGCCAC CACGGTGGTG 
GAATGGTTCT ACAGGCCCGA GGGCGGTAAA GATTTCCTTA TTTACGAGTA TCGGAATGGC 
CACCAGGAGG TGGAGAGCCC CTTTCAGGGG CGCCTGCAGT GGAATGGCAG CAAGGACCTG 
CAGGACGTGT CCATCACTGT GCTCAACGTC ACTCTGAACG ACTCTGGCCT CTACACCTGC 
AATGTGTCCC GGGAGTTTGA GTTTGAGGCG CATCGGCCCT TTGTGAAGAC GACGCGGCTG 
ATCCCCCTAA GAGTCACCGA GGAGGCTGGA GAGGACTTCA CCTCTGTGGT CTCAGAAATC 
ATGATGTACA TCCTTCTGGT CTTCCTCACC TTGTGGCTGC TCATCGAGAT GATATATTGC 
TACAGAAAGG TCTCAAAAGC CGAAGAGGCA GCCCAAGAAA ACGCGTCTGA CTACCTTGCC 
ATCCCATCTG AGAACAAGGA GAACTCTGCG GTACCAGTGG AGGAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SCN3B ( XM_011542897.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011541199.1 Homo sapiens sodium voltage-gated channel beta subunit 3 (SCN3B), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu16302
Clone ID Related Accession (Same CDS sequence)	XM_011542897.2 , XM_011542897.1 , NM_018400.3 , NM_001040151.1
Accession Version	XM_011542897.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 648bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	sodium channel subunit beta-3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCTGCCT TCAATAGATT GTTTCCCCTG GCTTCTCTCG TGCTTATCTA CTGGGTCAGT 
GTCTGCTTCC CTGTGTGTGT GGAAGTGCCC TCGGAGACGG AGGCCGTGCA GGGCAACCCC 
ATGAAGCTGC GCTGCATCTC CTGCATGAAG AGAGAGGAGG TGGAGGCCAC CACGGTGGTG 
GAATGGTTCT ACAGGCCCGA GGGCGGTAAA GATTTCCTTA TTTACGAGTA TCGGAATGGC 
CACCAGGAGG TGGAGAGCCC CTTTCAGGGG CGCCTGCAGT GGAATGGCAG CAAGGACCTG 
CAGGACGTGT CCATCACTGT GCTCAACGTC ACTCTGAACG ACTCTGGCCT CTACACCTGC 
AATGTGTCCC GGGAGTTTGA GTTTGAGGCG CATCGGCCCT TTGTGAAGAC GACGCGGCTG 
ATCCCCCTAA GAGTCACCGA GGAGGCTGGA GAGGACTTCA CCTCTGTGGT CTCAGAAATC 
ATGATGTACA TCCTTCTGGT CTTCCTCACC TTGTGGCTGC TCATCGAGAT GATATATTGC 
TACAGAAAGG TCTCAAAAGC CGAAGAGGCA GCCCAAGAAA ACGCGTCTGA CTACCTTGCC 
ATCCCATCTG AGAACAAGGA GAACTCTGCG GTACCAGTGG AGGAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011541199.1
CDS	408..1055
Translation	MPAFNRLFPLASLVLIYWVSVCFPVCVEVPSETEAVQGNPMKLRCISCMKREEVEATTVVEWFYRPEGGKDFLIYEYRNGHQEVESPFQGRLQWNGSKDLQDVSITVLNVTLNDSGLYTCNVSREFEFEAHRPFVKTTRLIPLRVTEEAGEDFTSVVSEIMMYILLVFLTLWLLIEMIYCYRKVSKAEEAAQENASDYLAIPSENKENSAVPVEE

Target ORF information:

RefSeq Version	XM_011542897.1
Organism	Homo sapiens(human)
Definition	Homo sapiens sodium voltage-gated channel beta subunit 3 (SCN3B), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011542897.1

ORF Insert Sequence:

ATGCCTGCCT TCAATAGATT GTTTCCCCTG GCTTCTCTCG TGCTTATCTA CTGGGTCAGT 
GTCTGCTTCC CTGTGTGTGT GGAAGTGCCC TCGGAGACGG AGGCCGTGCA GGGCAACCCC 
ATGAAGCTGC GCTGCATCTC CTGCATGAAG AGAGAGGAGG TGGAGGCCAC CACGGTGGTG 
GAATGGTTCT ACAGGCCCGA GGGCGGTAAA GATTTCCTTA TTTACGAGTA TCGGAATGGC 
CACCAGGAGG TGGAGAGCCC CTTTCAGGGG CGCCTGCAGT GGAATGGCAG CAAGGACCTG 
CAGGACGTGT CCATCACTGT GCTCAACGTC ACTCTGAACG ACTCTGGCCT CTACACCTGC 
AATGTGTCCC GGGAGTTTGA GTTTGAGGCG CATCGGCCCT TTGTGAAGAC GACGCGGCTG 
ATCCCCCTAA GAGTCACCGA GGAGGCTGGA GAGGACTTCA CCTCTGTGGT CTCAGAAATC 
ATGATGTACA TCCTTCTGGT CTTCCTCACC TTGTGGCTGC TCATCGAGAT GATATATTGC 
TACAGAAAGG TCTCAAAAGC CGAAGAGGCA GCCCAAGAAA ACGCGTCTGA CTACCTTGCC 
ATCCCATCTG AGAACAAGGA GAACTCTGCG GTACCAGTGG AGGAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

The role of the sodium current complex in a nonreferred nationwide cohort of sudden infant death syndrome.
Heart rhythm12(6)1241-9(2015 Jun)
Winkel BG,Yuan L,Olesen MS,Sadjadieh G,Wang Y,Risgaard B,Jabbari R,Hauns? S,Holst AG,Hollegaard MV,Tfelt-Hansen J,Jespersen T

Contribution of Cardiac Sodium Channel ?-Subunit Variants to Brugada Syndrome.
Circulation journal : official journal of the Japanese Circulation Society79(10)2118-29(2015)
Peeters U,Scornik F,Riur? H,P?rez G,Komurcu-Bayrak E,Van Malderen S,Pappaert G,Tarradas A,Pagans S,Daneels D,Breckpot K,Brugada P,Bonduelle M,Brugada R,Van Dooren S

Risk factors and genetics of atrial fibrillation.
Cardiology clinics32(4)485-94(2014 Nov)
Anumonwo JM,Kalifa J

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

SCN3B cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報