FGD6 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	FGD6
Entrez Gene ID	55785
Full Name	FYVE, RhoGEF and PH domain containing 6
Synonyms	ZFYVE24
General protein information	Preferred Names FYVE, RhoGEF and PH domain containing 6 Names FYVE, RhoGEF and PH domain-containing protein 6 zinc finger FYVE domain-containing protein 24
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 12 Map Location: 12q22
Disorder MIM:	613520

mRNA and Protein(s)

mRNA	Protein	Name
NM_018351.3	NP_060821.3	FYVE, RhoGEF and PH domain-containing protein 6
NM_018351.4	NP_060821.3	FYVE, RhoGEF and PH domain-containing protein 6

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	FGD6	XP_854794.2
Mus musculus (house mouse)	Fgd6	NP_444302.4
	FGD6	XP_001106559.1
Danio rerio (zebrafish)	fgd6	NP_001093450.1
Homo sapiens (human)	FGD6	NP_060821.3
Pan troglodytes (chimpanzee)	FGD6	XP_001142099.2
Xenopus tropicalis (tropical clawed frog)	fgd6	XP_002942756.2
Bos taurus (cattle)	FGD6	XP_005206185.1
Rattus norvegicus (Norway rat)	Fgd6	NP_001131117.1
Gallus gallus (chicken)	FGD6	XP_416149.4

Gene Ontology
Bibliography

Related articles in PubMed

A missense variant in FGD6 confers increased risk of polypoidal choroidal vasculopathy.
Huang L, Zhang H, Cheng CY, Wen F, Tam PO, Zhao P, Chen H, Li Z, Chen L, Tai Z, Yamashiro K, Deng S, Zhu X, Chen W, Cai L, Lu F, Li Y, Cheung CM, Shi Y, Miyake M, Lin Y, Gong B, Liu X, Sim KS, Yang J, Mori K, Zhang X, Cackett PD, Tsujikawa M, Nishida K, Hao F, Ma S, Lin H, Cheng J, Fei P, Lai TY, Tang S, Laude A, Inoue S, Yeo IY, Sakurada Y, Zhou Y, Iijima H, Honda S, Lei C, Zhang L, Zheng H, Jiang D, Zhu X, Wong TY, Khor CC, Pang CP, Yoshimura N, Yang Z
Nature genetics48(6)640-7(2016 06)

Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan.
Low SK, Chung S, Takahashi A, Zembutsu H, Mushiroda T, Kubo M, Nakamura Y
Cancer science104(8)1074-82(2013 Aug)

High-throughput mapping of a dynamic signaling network in mammalian cells.
Barrios-Rodiles M, Brown KR, Ozdamar B, Bose R, Liu Z, Donovan RS, Shinjo F, Liu Y, Dembowy J, Taylor IW, Luga V, Przulj N, Robinson M, Suzuki H, Hayashizaki Y, Jurisica I, Wrana JL
Science (New York, N.Y.)307(5715)1621-5(2005 Mar)

Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.
Jin J, Smith FD, Stark C, Wells CD, Fawcett JP, Kulkarni S, Metalnikov P, O'Donnell P, Taylor P, Taylor L, Zougman A, Woodgett JR, Langeberg LK, Scott JD, Pawson T
Current biology : CB14(16)1436-50(2004 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

data suggest that oxidized phospholipids and FGD6-Arg329 might act synergistically to increase susceptibility to PCV
Title: A missense variant in FGD6 confers increased risk of polypoidal choroidal vasculopathy.

The following FGD6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FGD6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu08865	NM_018351.4 Latest version!	Homo sapiens FYVE, RhoGEF and PH domain containing 6 (FGD6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$519.50-$727.30 $1039.00
View Old Accession Versions >>
OHu08865	NM_018351.3	Homo sapiens FYVE, RhoGEF and PH domain containing 6 (FGD6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$519.50-$727.30 $1039.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

FGD6 ( NM_018351.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_060821.3 Homo sapiens FYVE, RhoGEF and PH domain containing 6 (FGD6), mRNA.

Price & Availability↑

CloneID	OHu08865
Clone ID Related Accession (Same CDS sequence)	NM_018351.3 , NM_018351.4
Accession Version	NM_018351.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4293bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	FYVE, RhoGEF and PH domain-containing protein 6
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK124904.1, AK128492.1 and AC011598.33. On Jul 31, 2007 this sequence version replaced NM_018351.2. ##Evidence-Data-START## Transcript exon combination :: AK124904.1, SRR1660805.108148.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACTTCTG CAGCCGAGAT AAAGAAGCCA CCAGTGGCCC CCAAGCCCAA GTTTGTTGTG 
GCAAATAATA AGCCAGCCCC ACCTCCTATT GCACCTAAAC CCGACATTGT GATTTCTAGT 
GTTCCACAGT CGACAAAGAA AATGAAACCA GCAATAGCCC CAAAACCAAA AGTCCTGAAG 
ACCTCACCTG TTCGAGAGAT TGGGCAGTCG CCATCAAGGA AAATCATGTT GAACCTGGAA 
GGGCATAAAC AGGAATTAGC TGAAAGCACT GACAACTTTA ATTGTAAATA TGAAGGCAAT 
CAGAGCAATG ATTATATTTC ACCAATGTGT TCCTGCAGTT CTGAGTGTAT CCATAAGCTG 
GGCCATAGAG AGAATTTGTG TGTAAAGCAG CTTGTTTTAG AGCCCCTGGA AATGAATGAA 
AATTTAGAAA ACAGTAAAAT TGATGAGACT TTGACTATAA AAACTAGGAG TAAATGTGAT 
TTGTATGGTG AAAAAGCCAA GAACCAGGGT GGGGTTGTTT TAAAGGCAAG CGTTTTAGAA 
GAGGAGCTCA AAGATGCCTT AATACACCAA ATGCCACCTT TTATTTCTGC ACAGAAGCAC 
AGGCCCACAG ACAGCCCAGA AATGAATGGT GGCTGTAATT CAAATGGACA ATTCAGAATT 
GAATTTGCGG ATTTGTCACC TTCCCCATCC AGCTTTGAAA AAGTTCCTGA TCATCACAGT 
TGCCACTTAC AGCTTCCTAG TGATGAATGT GAACATTTTG AAACTTGCCA GGATGACAGT 
GAAAAAAGCA ATAATTGCTT TCAGTCATCT GAACTAGAGG CTCTGGAAAA TGGGAAAAGG 
AGTACTTTAA TATCTTCAGA TGGAGTTAGT AAGAAATCAG AAGTCAAAGA CCTTGGTCCC 
TTAGAAATTC ATTTAGTACC ATATACCCCA AAATTTCCAA CTCCCAAGCC CAGAAAGACA 
CGAACTGCTC GTCTGTTACG CCAAAAGTGT GTAGATACTC CTAGTGAAAG CACTGAAGAA 
CCGGGGAATT CAGACAGTAG CTCTTCCTGT CTTACTGAAA ATAGTTTGAA AATCAATAAA 
ATCAGTGTTC TGCATCAGAA TGTTTTGTGT AAGCAGGAAC AGGTGGATAA AATGAAGCTA 
GGAAATAAAA GTGAATTGAA TATGGAATCC AACAGTGATG CACAGGACTT AGTCAATTCA 
CAGAAAGCCA TGTGTAATGA AACAACTTCC TTTGAAAAAA TGGCACCTTC TTTTGATAAA 
GACTCTAATT TGAGTTCTGA CAGCACAACT GTAGATGGTT CTAGTATGTC GCTTGCTGTG 
GACGAAGGGA CCGGTTTTAT AAGATGTACT GTATCTATGA GCCTGCCTAA GCAGCTCAAA 
TTAACTTGCA ATGAACATTT GCAATCTGGG AGAAACCTGG GAGTTTCTGC CCCTCAAATG 
CAAAAGGAAT CTGTTATAAA AGAGGAAAAT TCTCTACGAA TTGTCCCCAA AAAACCTCAA 
AGACATAGCT TGCCTGCTAC AGGAGTGCTT AAAAAGGCTG CCTCCGAGGA GCTTTTGGAA 
AAAAGTTCTT ATCCTTCAAG TGAAGAAAAA AGTTCAGAGA AGAGTCTAGA AAGAAATCAC 
CTTCAGCATT TGTGTGCCCA AAACCGTGGT GTGTCATCCT CCTTTGATAT GCCTAAACGG 
GCTTCAGAAA AGCCAGTGTG GAAGTTACCT CATCCTATTT TACCCTTTTC AGGGAACCCA 
GAATTCTTAA AGTCTGTCAC CGTATCGTCA AACAGTGAGC CTTCAACAGC CCTAACCAAG 
CCCAGAGCAA AATCGTTATC TGCTATGGAT GTGGAAAAGT GCACTAAGCC TTGCAAAGAC 
TCTACAAAGA AAAACTCTTT TAAAAAGTTG CTCAGCATGA AACTGTCCAT CTGTTTCATG 
AAGAGTGACT TTCAAAAATT TTGGTCCAAG AGTAGCCAAC TCGGAGACAC CACCACAGGC 
CACCTCTCCA GTGGGGAGCA GAAGGGGATT GAAAGTGATT GGCAAGGCTT GTTGGTAGGA 
GAGGAGAAGA GAAGTAAACC CATCAAGGCA TATTCCACAG AAAACTATAG CCTGGAATCT 
CAAAAGAAGA GGAAGAAGTC TCGGGGCCAG ACCAGTGCAG CTAATGGTCT GAGAGCTGAG 
TCTTTGGATG ACCAAATGCT CTCCCGGGAG TCATCATCTC AGGCACCTTA CAAGTCTGTT 
ACAAGCCTCT GTGCACCGGA GTATGAAAAT ATACGCCATT ATGAGGAAAT ACCAGAGTAC 
GAGAACTTGC CATTTATTAT GGCTATACGG AAAACTCAAG AGTTGGAATG GCAGAATTCC 
AGCAGCATGG AGGACGCTGA TGCAAATGTG TATGAGGTAG AAGAGCCGTA TGAAGCTCCA 
GATGGCCAGC TGCAGCTTGG ACCCAGACAT CAGCATTCCA GTTCAGGAGC ATCCCAGGAG 
GAACAGAATG ATCTTGGTCT TGGTGACCTT CCCTCTGATG AGGAGGAAAT CATCAACAGT 
TCTGATGAAG ATGATGTCAG CTCTGAGTCA AGTAAAGGAG AGCCTGACCC ACTGGAAGAT 
AAACAGGATG AAGATAATGG AATGAAAAGT AAAGTTCATC ATATTGCCAA GGAGATCATG 
AGCTCAGAGA AAGTGTTTGT GGATGTGTTA AAACTTTTGC ATATTGATTT CCGGGATGCA 
GTAGCTCATG CTTCCAGGCA ACTTGGGAAA CCAGTGATTG AGGACCGGAT TCTAAATCAG 
ATCCTATACT ACTTGCCTCA GCTGTATGAG CTCAACCGGG ATCTCTTGAA GGAACTGGAG 
GAAAGAATGT TGCACTGGAC TGAACAACAA AGAATTGCTG ATATCTTTGT AAAGAAGGGA 
CCATATCTAA AAATGTATTC CACATACATC AAAGAATTTG ATAAGAATAT AGCCTTGCTG 
GATGAACAGT GCAAGAAAAA TCCAGGTTTT GCTGCTGTTG TTAGAGAATT TGAGATGAGC 
CCTCGCTGTG CTAATCTGGC CCTCAAGCAC TACCTGCTCA AGCCGGTTCA GAGGATCCCC 
CAGTACAGGC TGTTGCTGAC AGATTATTTG AAGAATCTCA TAGAAGATGC TGGAGATTAC 
AGAGACACTC AAGATGCCCT TGCTGTTGTT ATAGAGGTAG CCAACCACGC CAATGACACC 
ATGAAGCAAG GAGACAACTT TCAGAAACTT ATGCAAATTC AGTACAGCTT AAATGGACAC 
CATGAAATTG TGCAGCCTGG TCGGGTTTTT CTCAAAGAAG GAATTCTGAT GAAGCTGTCT 
CGGAAAGTGA TGCAACCTCG AATGTTTTTC CTGTTTAATG ATGCCCTGCT GTATACAACA 
CCAGTGCAGT CTGGGATGTA TAAACTGAAC AACATGCTCT CACTGGCTGG AATGAAGGTC 
AGAAAACCTA CCCAAGAAGC CTATCAGAAT GAATTAAAGA TTGAAAGTGT AGAACGTTCC 
TTCATTCTCT CAGCCAGTTC TGCCACAGAA AGGGATGAAT GGCTAGAAGC GATTTCCAGG 
GCAATAGAAG AGTATGCCAA GAAAAGAATC ACCTTCTGTC CTAGTAGGAG TCTTGATGAG 
GCAGACTCAG AAAATAAAGA AGAAGTTAGT CCTCTTGGAT CGAAGGCTCC CATCTGGATT 
CCTGATACCA GAGCCACAAT GTGTATGATC TGCACAAGCG AATTCACTCT CACCTGGAGA 
CGACACCACT GCCGGGCCTG TGGAAAGATT GTATGCCAAG CTTGTTCGTC TAATAAGTAT 
GGCTTAGATT ACCTGAAAAA TCAACCAGCA AGAGTATGTG AACATTGTTT CCAAGAACTG 
CAGAAATTAG ATCACCAGCA CTCCCCTAGG ATTGGATCTC CTGGAAATCA CAAATCTCCT 
TCAAGTGCCT TATCATCAGT CTTACATAGC ATTCCATCAG GGAGGAAACA GAAAAAAATC 
CCAGCTGCTC TCAAAGAAGT ATCAGCAAAC ACAGAGGATT CTTCTATGAG TGGCTACTTG 
TACAGATCAA AGGGCAATAA AAAACCCTGG AAACACTTTT GGTTTGTCAT AAAAAATAAA 
GTACTATATA CATATGCTGC AAGTGAGGAC GTGGCCGCTT TGGAGAGTCA GCCTTTATTA 
GGATTCACTG TTATTCAAGT TAAAGATGAG AATTCCGAGT CTAAAGTATT TCAGTTACTG 
CACAAAAACA TGTTATTTTA TGTATTCAAA GCAGAGGATG CTCATTCGGC TCAGAAGTGG 
ATAGAAGCAT TTCAGGAAGG CACAATATTG TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060821.3
CDS	225..4517
Translation	MTSAAEIKKPPVAPKPKFVVANNKPAPPPIAPKPDIVISSVPQSTKKMKPAIAPKPKVLKTSPVREIGQSPSRKIMLNLEGHKQELAESTDNFNCKYEGNQSNDYISPMCSCSSECIHKLGHRENLCVKQLVLEPLEMNENLENSKIDETLTIKTRSKCDLYGEKAKNQGGVVLKASVLEEELKDALIHQMPPFISAQKHRPTDSPEMNGGCNSNGQFRIEFADLSPSPSSFEKVPDHHSCHLQLPSDECEHFETCQDDSEKSNNCFQSSELEALENGKRSTLISSDGVSKKSEVKDLGPLEIHLVPYTPKFPTPKPRKTRTARLLRQKCVDTPSESTEEPGNSDSSSSCLTENSLKINKISVLHQNVLCKQEQVDKMKLGNKSELNMESNSDAQDLVNSQKAMCNETTSFEKMAPSFDKDSNLSSDSTTVDGSSMSLAVDEGTGFIRCTVSMSLPKQLKLTCNEHLQSGRNLGVSAPQMQKESVIKEENSLRIVPKKPQRHSLPATGVLKKAASEELLEKSSYPSSEEKSSEKSLERNHLQHLCAQNRGVSSSFDMPKRASEKPVWKLPHPILPFSGNPEFLKSVTVSSNSEPSTALTKPRAKSLSAMDVEKCTKPCKDSTKKNSFKKLLSMKLSICFMKSDFQKFWSKSSQLGDTTTGHLSSGEQKGIESDWQGLLVGEEKRSKPIKAYSTENYSLESQKKRKKSRGQTSAANGLRAESLDDQMLSRESSSQAPYKSVTSLCAPEYENIRHYEEIPEYENLPFIMAIRKTQELEWQNSSSMEDADANVYEVEEPYEAPDGQLQLGPRHQHSSSGASQEEQNDLGLGDLPSDEEEIINSSDEDDVSSESSKGEPDPLEDKQDEDNGMKSKVHHIAKEIMSSEKVFVDVLKLLHIDFRDAVAHASRQLGKPVIEDRILNQILYYLPQLYELNRDLLKELEERMLHWTEQQRIADIFVKKGPYLKMYSTYIKEFDKNIALLDEQCKKNPGFAAVVREFEMSPRCANLALKHYLLKPVQRIPQYRLLLTDYLKNLIEDAGDYRDTQDALAVVIEVANHANDTMKQGDNFQKLMQIQYSLNGHHEIVQPGRVFLKEGILMKLSRKVMQPRMFFLFNDALLYTTPVQSGMYKLNNMLSLAGMKVRKPTQEAYQNELKIESVERSFILSASSATERDEWLEAISRAIEEYAKKRITFCPSRSLDEADSENKEEVSPLGSKAPIWIPDTRATMCMICTSEFTLTWRRHHCRACGKIVCQACSSNKYGLDYLKNQPARVCEHCFQELQKLDHQHSPRIGSPGNHKSPSSALSSVLHSIPSGRKQKKIPAALKEVSANTEDSSMSGYLYRSKGNKKPWKHFWFVIKNKVLYTYAASEDVAALESQPLLGFTVIQVKDENSESKVFQLLHKNMLFYVFKAEDAHSAQKWIEAFQEGTIL

Target ORF information:

RefSeq Version	NM_018351.3
Organism	Homo sapiens(human)
Definition	Homo sapiens FYVE, RhoGEF and PH domain containing 6 (FGD6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018351.3

ORF Insert Sequence:

ATGACTTCTG CAGCCGAGAT AAAGAAGCCA CCAGTGGCCC CCAAGCCCAA GTTTGTTGTG 
GCAAATAATA AGCCAGCCCC ACCTCCTATT GCACCTAAAC CCGACATTGT GATTTCTAGT 
GTTCCACAGT CGACAAAGAA AATGAAACCA GCAATAGCCC CAAAACCAAA AGTCCTGAAG 
ACCTCACCTG TTCGAGAGAT TGGGCAGTCG CCATCAAGGA AAATCATGTT GAACCTGGAA 
GGGCATAAAC AGGAATTAGC TGAAAGCACT GACAACTTTA ATTGTAAATA TGAAGGCAAT 
CAGAGCAATG ATTATATTTC ACCAATGTGT TCCTGCAGTT CTGAGTGTAT CCATAAGCTG 
GGCCATAGAG AGAATTTGTG TGTAAAGCAG CTTGTTTTAG AGCCCCTGGA AATGAATGAA 
AATTTAGAAA ACAGTAAAAT TGATGAGACT TTGACTATAA AAACTAGGAG TAAATGTGAT 
TTGTATGGTG AAAAAGCCAA GAACCAGGGT GGGGTTGTTT TAAAGGCAAG CGTTTTAGAA 
GAGGAGCTCA AAGATGCCTT AATACACCAA ATGCCACCTT TTATTTCTGC ACAGAAGCAC 
AGGCCCACAG ACAGCCCAGA AATGAATGGT GGCTGTAATT CAAATGGACA ATTCAGAATT 
GAATTTGCGG ATTTGTCACC TTCCCCATCC AGCTTTGAAA AAGTTCCTGA TCATCACAGT 
TGCCACTTAC AGCTTCCTAG TGATGAATGT GAACATTTTG AAACTTGCCA GGATGACAGT 
GAAAAAAGCA ATAATTGCTT TCAGTCATCT GAACTAGAGG CTCTGGAAAA TGGGAAAAGG 
AGTACTTTAA TATCTTCAGA TGGAGTTAGT AAGAAATCAG AAGTCAAAGA CCTTGGTCCC 
TTAGAAATTC ATTTAGTACC ATATACCCCA AAATTTCCAA CTCCCAAGCC CAGAAAGACA 
CGAACTGCTC GTCTGTTACG CCAAAAGTGT GTAGATACTC CTAGTGAAAG CACTGAAGAA 
CCGGGGAATT CAGACAGTAG CTCTTCCTGT CTTACTGAAA ATAGTTTGAA AATCAATAAA 
ATCAGTGTTC TGCATCAGAA TGTTTTGTGT AAGCAGGAAC AGGTGGATAA AATGAAGCTA 
GGAAATAAAA GTGAATTGAA TATGGAATCC AACAGTGATG CACAGGACTT AGTCAATTCA 
CAGAAAGCCA TGTGTAATGA AACAACTTCC TTTGAAAAAA TGGCACCTTC TTTTGATAAA 
GACTCTAATT TGAGTTCTGA CAGCACAACT GTAGATGGTT CTAGTATGTC GCTTGCTGTG 
GACGAAGGGA CCGGTTTTAT AAGATGTACT GTATCTATGA GCCTGCCTAA GCAGCTCAAA 
TTAACTTGCA ATGAACATTT GCAATCTGGG AGAAACCTGG GAGTTTCTGC CCCTCAAATG 
CAAAAGGAAT CTGTTATAAA AGAGGAAAAT TCTCTACGAA TTGTCCCCAA AAAACCTCAA 
AGACATAGCT TGCCTGCTAC AGGAGTGCTT AAAAAGGCTG CCTCCGAGGA GCTTTTGGAA 
AAAAGTTCTT ATCCTTCAAG TGAAGAAAAA AGTTCAGAGA AGAGTCTAGA AAGAAATCAC 
CTTCAGCATT TGTGTGCCCA AAACCGTGGT GTGTCATCCT CCTTTGATAT GCCTAAACGG 
GCTTCAGAAA AGCCAGTGTG GAAGTTACCT CATCCTATTT TACCCTTTTC AGGGAACCCA 
GAATTCTTAA AGTCTGTCAC CGTATCGTCA AACAGTGAGC CTTCAACAGC CCTAACCAAG 
CCCAGAGCAA AATCGTTATC TGCTATGGAT GTGGAAAAGT GCACTAAGCC TTGCAAAGAC 
TCTACAAAGA AAAACTCTTT TAAAAAGTTG CTCAGCATGA AACTGTCCAT CTGTTTCATG 
AAGAGTGACT TTCAAAAATT TTGGTCCAAG AGTAGCCAAC TCGGAGACAC CACCACAGGC 
CACCTCTCCA GTGGGGAGCA GAAGGGGATT GAAAGTGATT GGCAAGGCTT GTTGGTAGGA 
GAGGAGAAGA GAAGTAAACC CATCAAGGCA TATTCCACAG AAAACTATAG CCTGGAATCT 
CAAAAGAAGA GGAAGAAGTC TCGGGGCCAG ACCAGTGCAG CTAATGGTCT GAGAGCTGAG 
TCTTTGGATG ACCAAATGCT CTCCCGGGAG TCATCATCTC AGGCACCTTA CAAGTCTGTT 
ACAAGCCTCT GTGCACCGGA GTATGAAAAT ATACGCCATT ATGAGGAAAT ACCAGAGTAC 
GAGAACTTGC CATTTATTAT GGCTATACGG AAAACTCAAG AGTTGGAATG GCAGAATTCC 
AGCAGCATGG AGGACGCTGA TGCAAATGTG TATGAGGTAG AAGAGCCGTA TGAAGCTCCA 
GATGGCCAGC TGCAGCTTGG ACCCAGACAT CAGCATTCCA GTTCAGGAGC ATCCCAGGAG 
GAACAGAATG ATCTTGGTCT TGGTGACCTT CCCTCTGATG AGGAGGAAAT CATCAACAGT 
TCTGATGAAG ATGATGTCAG CTCTGAGTCA AGTAAAGGAG AGCCTGACCC ACTGGAAGAT 
AAACAGGATG AAGATAATGG AATGAAAAGT AAAGTTCATC ATATTGCCAA GGAGATCATG 
AGCTCAGAGA AAGTGTTTGT GGATGTGTTA AAACTTTTGC ATATTGATTT CCGGGATGCA 
GTAGCTCATG CTTCCAGGCA ACTTGGGAAA CCAGTGATTG AGGACCGGAT TCTAAATCAG 
ATCCTATACT ACTTGCCTCA GCTGTATGAG CTCAACCGGG ATCTCTTGAA GGAACTGGAG 
GAAAGAATGT TGCACTGGAC TGAACAACAA AGAATTGCTG ATATCTTTGT AAAGAAGGGA 
CCATATCTAA AAATGTATTC CACATACATC AAAGAATTTG ATAAGAATAT AGCCTTGCTG 
GATGAACAGT GCAAGAAAAA TCCAGGTTTT GCTGCTGTTG TTAGAGAATT TGAGATGAGC 
CCTCGCTGTG CTAATCTGGC CCTCAAGCAC TACCTGCTCA AGCCGGTTCA GAGGATCCCC 
CAGTACAGGC TGTTGCTGAC AGATTATTTG AAGAATCTCA TAGAAGATGC TGGAGATTAC 
AGAGACACTC AAGATGCCCT TGCTGTTGTT ATAGAGGTAG CCAACCACGC CAATGACACC 
ATGAAGCAAG GAGACAACTT TCAGAAACTT ATGCAAATTC AGTACAGCTT AAATGGACAC 
CATGAAATTG TGCAGCCTGG TCGGGTTTTT CTCAAAGAAG GAATTCTGAT GAAGCTGTCT 
CGGAAAGTGA TGCAACCTCG AATGTTTTTC CTGTTTAATG ATGCCCTGCT GTATACAACA 
CCAGTGCAGT CTGGGATGTA TAAACTGAAC AACATGCTCT CACTGGCTGG AATGAAGGTC 
AGAAAACCTA CCCAAGAAGC CTATCAGAAT GAATTAAAGA TTGAAAGTGT AGAACGTTCC 
TTCATTCTCT CAGCCAGTTC TGCCACAGAA AGGGATGAAT GGCTAGAAGC GATTTCCAGG 
GCAATAGAAG AGTATGCCAA GAAAAGAATC ACCTTCTGTC CTAGTAGGAG TCTTGATGAG 
GCAGACTCAG AAAATAAAGA AGAAGTTAGT CCTCTTGGAT CGAAGGCTCC CATCTGGATT 
CCTGATACCA GAGCCACAAT GTGTATGATC TGCACAAGCG AATTCACTCT CACCTGGAGA 
CGACACCACT GCCGGGCCTG TGGAAAGATT GTATGCCAAG CTTGTTCGTC TAATAAGTAT 
GGCTTAGATT ACCTGAAAAA TCAACCAGCA AGAGTATGTG AACATTGTTT CCAAGAACTG 
CAGAAATTAG ATCACCAGCA CTCCCCTAGG ATTGGATCTC CTGGAAATCA CAAATCTCCT 
TCAAGTGCCT TATCATCAGT CTTACATAGC ATTCCATCAG GGAGGAAACA GAAAAAAATC 
CCAGCTGCTC TCAAAGAAGT ATCAGCAAAC ACAGAGGATT CTTCTATGAG TGGCTACTTG 
TACAGATCAA AGGGCAATAA AAAACCCTGG AAACACTTTT GGTTTGTCAT AAAAAATAAA 
GTACTATATA CATATGCTGC AAGTGAGGAC GTGGCCGCTT TGGAGAGTCA GCCTTTATTA 
GGATTCACTG TTATTCAAGT TAAAGATGAG AATTCCGAGT CTAAAGTATT TCAGTTACTG 
CACAAAAACA TGTTATTTTA TGTATTCAAA GCAGAGGATG CTCATTCGGC TCAGAAGTGG 
ATAGAAGCAT TTCAGGAAGG CACAATATTG TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FGD6 ( NM_018351.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_060821.3 Homo sapiens FYVE, RhoGEF and PH domain containing 6 (FGD6), mRNA.

Price & Availability↑

CloneID	OHu08865
Clone ID Related Accession (Same CDS sequence)	NM_018351.3 , NM_018351.4
Accession Version	NM_018351.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4293bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	FYVE, RhoGEF and PH domain-containing protein 6
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC127165.4, AK124904.1, AK128492.1 and AC011598.33. On Nov 22, 2018 this sequence version replaced NM_018351.3. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.108148.1, SRR1803616.101532.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000343958.9/ ENSP00000344446.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGACTTCTG CAGCCGAGAT AAAGAAGCCA CCAGTGGCCC CCAAGCCCAA GTTTGTTGTG 
GCAAATAATA AGCCAGCCCC ACCTCCTATT GCACCTAAAC CCGACATTGT GATTTCTAGT 
GTTCCACAGT CGACAAAGAA AATGAAACCA GCAATAGCCC CAAAACCAAA AGTCCTGAAG 
ACCTCACCTG TTCGAGAGAT TGGGCAGTCG CCATCAAGGA AAATCATGTT GAACCTGGAA 
GGGCATAAAC AGGAATTAGC TGAAAGCACT GACAACTTTA ATTGTAAATA TGAAGGCAAT 
CAGAGCAATG ATTATATTTC ACCAATGTGT TCCTGCAGTT CTGAGTGTAT CCATAAGCTG 
GGCCATAGAG AGAATTTGTG TGTAAAGCAG CTTGTTTTAG AGCCCCTGGA AATGAATGAA 
AATTTAGAAA ACAGTAAAAT TGATGAGACT TTGACTATAA AAACTAGGAG TAAATGTGAT 
TTGTATGGTG AAAAAGCCAA GAACCAGGGT GGGGTTGTTT TAAAGGCAAG CGTTTTAGAA 
GAGGAGCTCA AAGATGCCTT AATACACCAA ATGCCACCTT TTATTTCTGC ACAGAAGCAC 
AGGCCCACAG ACAGCCCAGA AATGAATGGT GGCTGTAATT CAAATGGACA ATTCAGAATT 
GAATTTGCGG ATTTGTCACC TTCCCCATCC AGCTTTGAAA AAGTTCCTGA TCATCACAGT 
TGCCACTTAC AGCTTCCTAG TGATGAATGT GAACATTTTG AAACTTGCCA GGATGACAGT 
GAAAAAAGCA ATAATTGCTT TCAGTCATCT GAACTAGAGG CTCTGGAAAA TGGGAAAAGG 
AGTACTTTAA TATCTTCAGA TGGAGTTAGT AAGAAATCAG AAGTCAAAGA CCTTGGTCCC 
TTAGAAATTC ATTTAGTACC ATATACCCCA AAATTTCCAA CTCCCAAGCC CAGAAAGACA 
CGAACTGCTC GTCTGTTACG CCAAAAGTGT GTAGATACTC CTAGTGAAAG CACTGAAGAA 
CCGGGGAATT CAGACAGTAG CTCTTCCTGT CTTACTGAAA ATAGTTTGAA AATCAATAAA 
ATCAGTGTTC TGCATCAGAA TGTTTTGTGT AAGCAGGAAC AGGTGGATAA AATGAAGCTA 
GGAAATAAAA GTGAATTGAA TATGGAATCC AACAGTGATG CACAGGACTT AGTCAATTCA 
CAGAAAGCCA TGTGTAATGA AACAACTTCC TTTGAAAAAA TGGCACCTTC TTTTGATAAA 
GACTCTAATT TGAGTTCTGA CAGCACAACT GTAGATGGTT CTAGTATGTC GCTTGCTGTG 
GACGAAGGGA CCGGTTTTAT AAGATGTACT GTATCTATGA GCCTGCCTAA GCAGCTCAAA 
TTAACTTGCA ATGAACATTT GCAATCTGGG AGAAACCTGG GAGTTTCTGC CCCTCAAATG 
CAAAAGGAAT CTGTTATAAA AGAGGAAAAT TCTCTACGAA TTGTCCCCAA AAAACCTCAA 
AGACATAGCT TGCCTGCTAC AGGAGTGCTT AAAAAGGCTG CCTCCGAGGA GCTTTTGGAA 
AAAAGTTCTT ATCCTTCAAG TGAAGAAAAA AGTTCAGAGA AGAGTCTAGA AAGAAATCAC 
CTTCAGCATT TGTGTGCCCA AAACCGTGGT GTGTCATCCT CCTTTGATAT GCCTAAACGG 
GCTTCAGAAA AGCCAGTGTG GAAGTTACCT CATCCTATTT TACCCTTTTC AGGGAACCCA 
GAATTCTTAA AGTCTGTCAC CGTATCGTCA AACAGTGAGC CTTCAACAGC CCTAACCAAG 
CCCAGAGCAA AATCGTTATC TGCTATGGAT GTGGAAAAGT GCACTAAGCC TTGCAAAGAC 
TCTACAAAGA AAAACTCTTT TAAAAAGTTG CTCAGCATGA AACTGTCCAT CTGTTTCATG 
AAGAGTGACT TTCAAAAATT TTGGTCCAAG AGTAGCCAAC TCGGAGACAC CACCACAGGC 
CACCTCTCCA GTGGGGAGCA GAAGGGGATT GAAAGTGATT GGCAAGGCTT GTTGGTAGGA 
GAGGAGAAGA GAAGTAAACC CATCAAGGCA TATTCCACAG AAAACTATAG CCTGGAATCT 
CAAAAGAAGA GGAAGAAGTC TCGGGGCCAG ACCAGTGCAG CTAATGGTCT GAGAGCTGAG 
TCTTTGGATG ACCAAATGCT CTCCCGGGAG TCATCATCTC AGGCACCTTA CAAGTCTGTT 
ACAAGCCTCT GTGCACCGGA GTATGAAAAT ATACGCCATT ATGAGGAAAT ACCAGAGTAC 
GAGAACTTGC CATTTATTAT GGCTATACGG AAAACTCAAG AGTTGGAATG GCAGAATTCC 
AGCAGCATGG AGGACGCTGA TGCAAATGTG TATGAGGTAG AAGAGCCGTA TGAAGCTCCA 
GATGGCCAGC TGCAGCTTGG ACCCAGACAT CAGCATTCCA GTTCAGGAGC ATCCCAGGAG 
GAACAGAATG ATCTTGGTCT TGGTGACCTT CCCTCTGATG AGGAGGAAAT CATCAACAGT 
TCTGATGAAG ATGATGTCAG CTCTGAGTCA AGTAAAGGAG AGCCTGACCC ACTGGAAGAT 
AAACAGGATG AAGATAATGG AATGAAAAGT AAAGTTCATC ATATTGCCAA GGAGATCATG 
AGCTCAGAGA AAGTGTTTGT GGATGTGTTA AAACTTTTGC ATATTGATTT CCGGGATGCA 
GTAGCTCATG CTTCCAGGCA ACTTGGGAAA CCAGTGATTG AGGACCGGAT TCTAAATCAG 
ATCCTATACT ACTTGCCTCA GCTGTATGAG CTCAACCGGG ATCTCTTGAA GGAACTGGAG 
GAAAGAATGT TGCACTGGAC TGAACAACAA AGAATTGCTG ATATCTTTGT AAAGAAGGGA 
CCATATCTAA AAATGTATTC CACATACATC AAAGAATTTG ATAAGAATAT AGCCTTGCTG 
GATGAACAGT GCAAGAAAAA TCCAGGTTTT GCTGCTGTTG TTAGAGAATT TGAGATGAGC 
CCTCGCTGTG CTAATCTGGC CCTCAAGCAC TACCTGCTCA AGCCGGTTCA GAGGATCCCC 
CAGTACAGGC TGTTGCTGAC AGATTATTTG AAGAATCTCA TAGAAGATGC TGGAGATTAC 
AGAGACACTC AAGATGCCCT TGCTGTTGTT ATAGAGGTAG CCAACCACGC CAATGACACC 
ATGAAGCAAG GAGACAACTT TCAGAAACTT ATGCAAATTC AGTACAGCTT AAATGGACAC 
CATGAAATTG TGCAGCCTGG TCGGGTTTTT CTCAAAGAAG GAATTCTGAT GAAGCTGTCT 
CGGAAAGTGA TGCAACCTCG AATGTTTTTC CTGTTTAATG ATGCCCTGCT GTATACAACA 
CCAGTGCAGT CTGGGATGTA TAAACTGAAC AACATGCTCT CACTGGCTGG AATGAAGGTC 
AGAAAACCTA CCCAAGAAGC CTATCAGAAT GAATTAAAGA TTGAAAGTGT AGAACGTTCC 
TTCATTCTCT CAGCCAGTTC TGCCACAGAA AGGGATGAAT GGCTAGAAGC GATTTCCAGG 
GCAATAGAAG AGTATGCCAA GAAAAGAATC ACCTTCTGTC CTAGTAGGAG TCTTGATGAG 
GCAGACTCAG AAAATAAAGA AGAAGTTAGT CCTCTTGGAT CGAAGGCTCC CATCTGGATT 
CCTGATACCA GAGCCACAAT GTGTATGATC TGCACAAGCG AATTCACTCT CACCTGGAGA 
CGACACCACT GCCGGGCCTG TGGAAAGATT GTATGCCAAG CTTGTTCGTC TAATAAGTAT 
GGCTTAGATT ACCTGAAAAA TCAACCAGCA AGAGTATGTG AACATTGTTT CCAAGAACTG 
CAGAAATTAG ATCACCAGCA CTCCCCTAGG ATTGGATCTC CTGGAAATCA CAAATCTCCT 
TCAAGTGCCT TATCATCAGT CTTACATAGC ATTCCATCAG GGAGGAAACA GAAAAAAATC 
CCAGCTGCTC TCAAAGAAGT ATCAGCAAAC ACAGAGGATT CTTCTATGAG TGGCTACTTG 
TACAGATCAA AGGGCAATAA AAAACCCTGG AAACACTTTT GGTTTGTCAT AAAAAATAAA 
GTACTATATA CATATGCTGC AAGTGAGGAC GTGGCCGCTT TGGAGAGTCA GCCTTTATTA 
GGATTCACTG TTATTCAAGT TAAAGATGAG AATTCCGAGT CTAAAGTATT TCAGTTACTG 
CACAAAAACA TGTTATTTTA TGTATTCAAA GCAGAGGATG CTCATTCGGC TCAGAAGTGG 
ATAGAAGCAT TTCAGGAAGG CACAATATTG TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060821.3
CDS	228..4520
Translation	MTSAAEIKKPPVAPKPKFVVANNKPAPPPIAPKPDIVISSVPQSTKKMKPAIAPKPKVLKTSPVREIGQSPSRKIMLNLEGHKQELAESTDNFNCKYEGNQSNDYISPMCSCSSECIHKLGHRENLCVKQLVLEPLEMNENLENSKIDETLTIKTRSKCDLYGEKAKNQGGVVLKASVLEEELKDALIHQMPPFISAQKHRPTDSPEMNGGCNSNGQFRIEFADLSPSPSSFEKVPDHHSCHLQLPSDECEHFETCQDDSEKSNNCFQSSELEALENGKRSTLISSDGVSKKSEVKDLGPLEIHLVPYTPKFPTPKPRKTRTARLLRQKCVDTPSESTEEPGNSDSSSSCLTENSLKINKISVLHQNVLCKQEQVDKMKLGNKSELNMESNSDAQDLVNSQKAMCNETTSFEKMAPSFDKDSNLSSDSTTVDGSSMSLAVDEGTGFIRCTVSMSLPKQLKLTCNEHLQSGRNLGVSAPQMQKESVIKEENSLRIVPKKPQRHSLPATGVLKKAASEELLEKSSYPSSEEKSSEKSLERNHLQHLCAQNRGVSSSFDMPKRASEKPVWKLPHPILPFSGNPEFLKSVTVSSNSEPSTALTKPRAKSLSAMDVEKCTKPCKDSTKKNSFKKLLSMKLSICFMKSDFQKFWSKSSQLGDTTTGHLSSGEQKGIESDWQGLLVGEEKRSKPIKAYSTENYSLESQKKRKKSRGQTSAANGLRAESLDDQMLSRESSSQAPYKSVTSLCAPEYENIRHYEEIPEYENLPFIMAIRKTQELEWQNSSSMEDADANVYEVEEPYEAPDGQLQLGPRHQHSSSGASQEEQNDLGLGDLPSDEEEIINSSDEDDVSSESSKGEPDPLEDKQDEDNGMKSKVHHIAKEIMSSEKVFVDVLKLLHIDFRDAVAHASRQLGKPVIEDRILNQILYYLPQLYELNRDLLKELEERMLHWTEQQRIADIFVKKGPYLKMYSTYIKEFDKNIALLDEQCKKNPGFAAVVREFEMSPRCANLALKHYLLKPVQRIPQYRLLLTDYLKNLIEDAGDYRDTQDALAVVIEVANHANDTMKQGDNFQKLMQIQYSLNGHHEIVQPGRVFLKEGILMKLSRKVMQPRMFFLFNDALLYTTPVQSGMYKLNNMLSLAGMKVRKPTQEAYQNELKIESVERSFILSASSATERDEWLEAISRAIEEYAKKRITFCPSRSLDEADSENKEEVSPLGSKAPIWIPDTRATMCMICTSEFTLTWRRHHCRACGKIVCQACSSNKYGLDYLKNQPARVCEHCFQELQKLDHQHSPRIGSPGNHKSPSSALSSVLHSIPSGRKQKKIPAALKEVSANTEDSSMSGYLYRSKGNKKPWKHFWFVIKNKVLYTYAASEDVAALESQPLLGFTVIQVKDENSESKVFQLLHKNMLFYVFKAEDAHSAQKWIEAFQEGTIL

Target ORF information:

RefSeq Version	NM_018351.4
Organism	Homo sapiens(human)
Definition	Homo sapiens FYVE, RhoGEF and PH domain containing 6 (FGD6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018351.4

ORF Insert Sequence:

ATGACTTCTG CAGCCGAGAT AAAGAAGCCA CCAGTGGCCC CCAAGCCCAA GTTTGTTGTG 
GCAAATAATA AGCCAGCCCC ACCTCCTATT GCACCTAAAC CCGACATTGT GATTTCTAGT 
GTTCCACAGT CGACAAAGAA AATGAAACCA GCAATAGCCC CAAAACCAAA AGTCCTGAAG 
ACCTCACCTG TTCGAGAGAT TGGGCAGTCG CCATCAAGGA AAATCATGTT GAACCTGGAA 
GGGCATAAAC AGGAATTAGC TGAAAGCACT GACAACTTTA ATTGTAAATA TGAAGGCAAT 
CAGAGCAATG ATTATATTTC ACCAATGTGT TCCTGCAGTT CTGAGTGTAT CCATAAGCTG 
GGCCATAGAG AGAATTTGTG TGTAAAGCAG CTTGTTTTAG AGCCCCTGGA AATGAATGAA 
AATTTAGAAA ACAGTAAAAT TGATGAGACT TTGACTATAA AAACTAGGAG TAAATGTGAT 
TTGTATGGTG AAAAAGCCAA GAACCAGGGT GGGGTTGTTT TAAAGGCAAG CGTTTTAGAA 
GAGGAGCTCA AAGATGCCTT AATACACCAA ATGCCACCTT TTATTTCTGC ACAGAAGCAC 
AGGCCCACAG ACAGCCCAGA AATGAATGGT GGCTGTAATT CAAATGGACA ATTCAGAATT 
GAATTTGCGG ATTTGTCACC TTCCCCATCC AGCTTTGAAA AAGTTCCTGA TCATCACAGT 
TGCCACTTAC AGCTTCCTAG TGATGAATGT GAACATTTTG AAACTTGCCA GGATGACAGT 
GAAAAAAGCA ATAATTGCTT TCAGTCATCT GAACTAGAGG CTCTGGAAAA TGGGAAAAGG 
AGTACTTTAA TATCTTCAGA TGGAGTTAGT AAGAAATCAG AAGTCAAAGA CCTTGGTCCC 
TTAGAAATTC ATTTAGTACC ATATACCCCA AAATTTCCAA CTCCCAAGCC CAGAAAGACA 
CGAACTGCTC GTCTGTTACG CCAAAAGTGT GTAGATACTC CTAGTGAAAG CACTGAAGAA 
CCGGGGAATT CAGACAGTAG CTCTTCCTGT CTTACTGAAA ATAGTTTGAA AATCAATAAA 
ATCAGTGTTC TGCATCAGAA TGTTTTGTGT AAGCAGGAAC AGGTGGATAA AATGAAGCTA 
GGAAATAAAA GTGAATTGAA TATGGAATCC AACAGTGATG CACAGGACTT AGTCAATTCA 
CAGAAAGCCA TGTGTAATGA AACAACTTCC TTTGAAAAAA TGGCACCTTC TTTTGATAAA 
GACTCTAATT TGAGTTCTGA CAGCACAACT GTAGATGGTT CTAGTATGTC GCTTGCTGTG 
GACGAAGGGA CCGGTTTTAT AAGATGTACT GTATCTATGA GCCTGCCTAA GCAGCTCAAA 
TTAACTTGCA ATGAACATTT GCAATCTGGG AGAAACCTGG GAGTTTCTGC CCCTCAAATG 
CAAAAGGAAT CTGTTATAAA AGAGGAAAAT TCTCTACGAA TTGTCCCCAA AAAACCTCAA 
AGACATAGCT TGCCTGCTAC AGGAGTGCTT AAAAAGGCTG CCTCCGAGGA GCTTTTGGAA 
AAAAGTTCTT ATCCTTCAAG TGAAGAAAAA AGTTCAGAGA AGAGTCTAGA AAGAAATCAC 
CTTCAGCATT TGTGTGCCCA AAACCGTGGT GTGTCATCCT CCTTTGATAT GCCTAAACGG 
GCTTCAGAAA AGCCAGTGTG GAAGTTACCT CATCCTATTT TACCCTTTTC AGGGAACCCA 
GAATTCTTAA AGTCTGTCAC CGTATCGTCA AACAGTGAGC CTTCAACAGC CCTAACCAAG 
CCCAGAGCAA AATCGTTATC TGCTATGGAT GTGGAAAAGT GCACTAAGCC TTGCAAAGAC 
TCTACAAAGA AAAACTCTTT TAAAAAGTTG CTCAGCATGA AACTGTCCAT CTGTTTCATG 
AAGAGTGACT TTCAAAAATT TTGGTCCAAG AGTAGCCAAC TCGGAGACAC CACCACAGGC 
CACCTCTCCA GTGGGGAGCA GAAGGGGATT GAAAGTGATT GGCAAGGCTT GTTGGTAGGA 
GAGGAGAAGA GAAGTAAACC CATCAAGGCA TATTCCACAG AAAACTATAG CCTGGAATCT 
CAAAAGAAGA GGAAGAAGTC TCGGGGCCAG ACCAGTGCAG CTAATGGTCT GAGAGCTGAG 
TCTTTGGATG ACCAAATGCT CTCCCGGGAG TCATCATCTC AGGCACCTTA CAAGTCTGTT 
ACAAGCCTCT GTGCACCGGA GTATGAAAAT ATACGCCATT ATGAGGAAAT ACCAGAGTAC 
GAGAACTTGC CATTTATTAT GGCTATACGG AAAACTCAAG AGTTGGAATG GCAGAATTCC 
AGCAGCATGG AGGACGCTGA TGCAAATGTG TATGAGGTAG AAGAGCCGTA TGAAGCTCCA 
GATGGCCAGC TGCAGCTTGG ACCCAGACAT CAGCATTCCA GTTCAGGAGC ATCCCAGGAG 
GAACAGAATG ATCTTGGTCT TGGTGACCTT CCCTCTGATG AGGAGGAAAT CATCAACAGT 
TCTGATGAAG ATGATGTCAG CTCTGAGTCA AGTAAAGGAG AGCCTGACCC ACTGGAAGAT 
AAACAGGATG AAGATAATGG AATGAAAAGT AAAGTTCATC ATATTGCCAA GGAGATCATG 
AGCTCAGAGA AAGTGTTTGT GGATGTGTTA AAACTTTTGC ATATTGATTT CCGGGATGCA 
GTAGCTCATG CTTCCAGGCA ACTTGGGAAA CCAGTGATTG AGGACCGGAT TCTAAATCAG 
ATCCTATACT ACTTGCCTCA GCTGTATGAG CTCAACCGGG ATCTCTTGAA GGAACTGGAG 
GAAAGAATGT TGCACTGGAC TGAACAACAA AGAATTGCTG ATATCTTTGT AAAGAAGGGA 
CCATATCTAA AAATGTATTC CACATACATC AAAGAATTTG ATAAGAATAT AGCCTTGCTG 
GATGAACAGT GCAAGAAAAA TCCAGGTTTT GCTGCTGTTG TTAGAGAATT TGAGATGAGC 
CCTCGCTGTG CTAATCTGGC CCTCAAGCAC TACCTGCTCA AGCCGGTTCA GAGGATCCCC 
CAGTACAGGC TGTTGCTGAC AGATTATTTG AAGAATCTCA TAGAAGATGC TGGAGATTAC 
AGAGACACTC AAGATGCCCT TGCTGTTGTT ATAGAGGTAG CCAACCACGC CAATGACACC 
ATGAAGCAAG GAGACAACTT TCAGAAACTT ATGCAAATTC AGTACAGCTT AAATGGACAC 
CATGAAATTG TGCAGCCTGG TCGGGTTTTT CTCAAAGAAG GAATTCTGAT GAAGCTGTCT 
CGGAAAGTGA TGCAACCTCG AATGTTTTTC CTGTTTAATG ATGCCCTGCT GTATACAACA 
CCAGTGCAGT CTGGGATGTA TAAACTGAAC AACATGCTCT CACTGGCTGG AATGAAGGTC 
AGAAAACCTA CCCAAGAAGC CTATCAGAAT GAATTAAAGA TTGAAAGTGT AGAACGTTCC 
TTCATTCTCT CAGCCAGTTC TGCCACAGAA AGGGATGAAT GGCTAGAAGC GATTTCCAGG 
GCAATAGAAG AGTATGCCAA GAAAAGAATC ACCTTCTGTC CTAGTAGGAG TCTTGATGAG 
GCAGACTCAG AAAATAAAGA AGAAGTTAGT CCTCTTGGAT CGAAGGCTCC CATCTGGATT 
CCTGATACCA GAGCCACAAT GTGTATGATC TGCACAAGCG AATTCACTCT CACCTGGAGA 
CGACACCACT GCCGGGCCTG TGGAAAGATT GTATGCCAAG CTTGTTCGTC TAATAAGTAT 
GGCTTAGATT ACCTGAAAAA TCAACCAGCA AGAGTATGTG AACATTGTTT CCAAGAACTG 
CAGAAATTAG ATCACCAGCA CTCCCCTAGG ATTGGATCTC CTGGAAATCA CAAATCTCCT 
TCAAGTGCCT TATCATCAGT CTTACATAGC ATTCCATCAG GGAGGAAACA GAAAAAAATC 
CCAGCTGCTC TCAAAGAAGT ATCAGCAAAC ACAGAGGATT CTTCTATGAG TGGCTACTTG 
TACAGATCAA AGGGCAATAA AAAACCCTGG AAACACTTTT GGTTTGTCAT AAAAAATAAA 
GTACTATATA CATATGCTGC AAGTGAGGAC GTGGCCGCTT TGGAGAGTCA GCCTTTATTA 
GGATTCACTG TTATTCAAGT TAAAGATGAG AATTCCGAGT CTAAAGTATT TCAGTTACTG 
CACAAAAACA TGTTATTTTA TGTATTCAAA GCAGAGGATG CTCATTCGGC TCAGAAGTGG 
ATAGAAGCAT TTCAGGAAGG CACAATATTG TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A missense variant in FGD6 confers increased risk of polypoidal choroidal vasculopathy.
Nature genetics48(6)640-7(2016 06)
Huang L,Zhang H,Cheng CY,Wen F,Tam PO,Zhao P,Chen H,Li Z,Chen L,Tai Z,Yamashiro K,Deng S,Zhu X,Chen W,Cai L,Lu F,Li Y,Cheung CM,Shi Y,Miyake M,Lin Y,Gong B,Liu X,Sim KS,Yang J,Mori K,Zhang X,Cackett PD,Tsujikawa M,Nishida K,Hao F,Ma S,Lin H,Cheng J,Fei P,Lai TY,Tang S,Laude A,Inoue S,Yeo IY,Sakurada Y,Zhou Y,Iijima H,Honda S,Lei C,Zhang L,Zheng H,Jiang D,Zhu X,Wong TY,Khor CC,Pang CP,Yoshimura N,Yang Z

Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan.
Cancer science104(8)1074-82(2013 Aug)
Low SK,Chung S,Takahashi A,Zembutsu H,Mushiroda T,Kubo M,Nakamura Y

High-throughput mapping of a dynamic signaling network in mammalian cells.
Science (New York, N.Y.)307(5715)1621-5(2005 Mar)
Barrios-Rodiles M,Brown KR,Ozdamar B,Bose R,Liu Z,Donovan RS,Shinjo F,Liu Y,Dembowy J,Taylor IW,Luga V,Przulj N,Robinson M,Suzuki H,Hayashizaki Y,Jurisica I,Wrana JL

Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.
Current biology : CB14(16)1436-50(2004 Aug)
Jin J,Smith FD,Stark C,Wells CD,Fawcett JP,Kulkarni S,Metalnikov P,O'Donnell P,Taylor P,Taylor L,Zougman A,Woodgett JR,Langeberg LK,Scott JD,Pawson T

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FGD6 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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