TSR1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TSR1
Entrez Gene ID	55720
Full Name	TSR1, ribosome maturation factor
General protein information	Preferred Names TSR1, ribosome maturation factor Names pre-rRNA-processing protein TSR1 homolog
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17p13.3
Disorder MIM:	611214

mRNA and Protein(s)

mRNA	Protein	Name
NM_018128.4	NP_060598.3	pre-rRNA-processing protein TSR1 homolog
NM_018128.5	NP_060598.3	pre-rRNA-processing protein TSR1 homolog

Pathways from BioSystems

Homologies

Homo sapiens (human)	TSR1	NP_060598.3
Rattus norvegicus (Norway rat)	Tsr1	XP_002727820.1
Saccharomyces cerevisiae (baker's yeast)	TSR1	NP_010223.1
Schizosaccharomyces pombe (fission yeast)	SPAC23H4.15	NP_593391.1
Canis lupus familiaris (dog)	LOC610048	XP_852531.1
Mus musculus (house mouse)	Tsr1	NP_796299.2
Caenorhabditis elegans (roundworm)	tag-151	NP_494840.1
Magnaporthe oryzae (rice blast fungus)	MGG_01087	XP_003717850.1
Arabidopsis thaliana (thale cress)	AT1G42440	NP_564480.1
Pan troglodytes (chimpanzee)	TSR1	XP_003315339.1
	TSR1	XP_001086730.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP009438	XP_307850.4
Kluyveromyces lactis	KLLA0E05149g	XP_454177.1
Neurospora crassa	NCU01503	XP_956952.1
Canis lupus familiaris (dog)	TSR1	XP_548321.4
Gallus gallus (chicken)	LOC100857289	XP_004946616.1
Drosophila melanogaster (fruit fly)	CG7338	NP_649304.1
Bos taurus (cattle)	TSR1	NP_001095403.1
Danio rerio (zebrafish)	tsr1	NP_001032447.2
Eremothecium gossypii	AGOS_AER051C	NP_984911.1
Oryza sativa (rice)	Os11g0298400	NP_001067728.1

Gene Ontology
Bibliography

Related articles in PubMed

Biological insights from 108 schizophrenia-associated genetic loci.

Nature511(7510)421-7(2014 Jul)

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J, Hentze MW
Cell149(6)1393-406(2012 Jun)

Analysis of two human pre-ribosomal factors, bystin and hTsr1, highlights differences in evolution of ribosome biogenesis between yeast and mammals.
Carron C, O'Donohue MF, Choesmel V, Faubladier M, Gleizes PE
Nucleic acids research39(1)280-91(2011 Jan)

Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data.
Vasan RS, Glazer NL, Felix JF, Lieb W, Wild PS, Felix SB, Watzinger N, Larson MG, Smith NL, Dehghan A, Grosshennig A, Schillert A, Teumer A, Schmidt R, Kathiresan S, Lumley T, Aulchenko YS, K?nig IR, Zeller T, Homuth G, Struchalin M, Aragam J, Bis JC, Rivadeneira F, Erdmann J, Schnabel RB, D?rr M, Zweiker R, Lind L, Rodeheffer RJ, Greiser KH, Levy D, Haritunians T, Deckers JW, Stritzke J, Lackner KJ, V?lker U, Ingelsson E, Kullo I, Haerting J, O'Donnell CJ, Heckbert SR, Stricker BH, Ziegler A, Reffelmann T, Redfield MM, Werdan K, Mitchell GF, Rice K, Arnett DK, Hofman A, Gottdiener JS, Uitterlinden AG, Meitinger T, Blettner M, Friedrich N, Wang TJ, Psaty BM, van Duijn CM, Wichmann HE, Munzel TF, Kroemer HK, Benjamin EJ, Rotter JI, Witteman JC, Schunkert H, Schmidt H, V?lzke H, Blankenberg S
JAMA302(2)168-78(2009 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

hTsr1 is involved downstream in nuclear export of the pre-40S particles.
Title: Analysis of two human pre-ribosomal factors, bystin and hTsr1, highlights differences in evolution of ribosome biogenesis between yeast and mammals.

Meta-analysis and genome-wide association study of gene-disease association. (HuGE Navigator)
Title: Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data.

The following TSR1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TSR1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu02946	NM_018128.5 Latest version!	Homo sapiens TSR1 ribosome maturation factor (TSR1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
View Old Accession Versions >>
OHu02946	NM_018128.4	Homo sapiens TSR1 ribosome maturation factor (TSR1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TSR1 ( NM_018128.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_060598.3 Homo sapiens TSR1 ribosome maturation factor (TSR1), mRNA.

Price & Availability↑

CloneID	OHu02946
Clone ID Related Accession (Same CDS sequence)	NM_018128.4 , NM_018128.5
Accession Version	NM_018128.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2415bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-03
Organism	Homo sapiens(human)
Product	pre-rRNA-processing protein TSR1 homolog
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AB037822.1, BC019090.2 and AK026565.1. On Dec 12, 2003 this sequence version replaced NM_018128.3. ##Evidence-Data-START## Transcript exon combination :: BC110851.1, AB037822.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCCC ACCGCCCCGG CCCGCTCAAG CAGCAGAATA AAGCTCATAA AGGCGGACGG 
CATCGGGGTC GGGGATCTGC ACAGCGGGAC GGCAAGGGCC GTCTGGCACT GAAAACCCTA 
AGCAAGAAGG TGAGAAAAGA ACTCAGCAGA GTCGACCAGA GGCATCGCGC CAGCCAGCTC 
CGAAAGCAGA AGAAGGAGGC GGTTCTGGCA GAGAAGAGAC AGCTGGGTGG CAAGGATGGC 
CCTCCTCATC AGGTACTGGT GGTGCCCCTG CACAGCAGAA TTTCCCTGCC AGAGGCCATG 
CAGCTGCTTC AAGATAGGGA CACTGGAACA GTACACTTGA ATGAATTGGG AAACACCCAG 
AACTTTATGC TGCTGTGCCC CCGCTTGAAA CATCGGTGGT TTTTCACCTC AGCAAGGCCA 
GGGGATCTGC ACGTTGTGTT AGACATGGCT AAAGTAGCTG ATACCATCCT GTTCCTCCTT 
GATCCACTAG AAGGCTGGGA CAGCACCGGT GATTACTGTC TTTCCTGCCT CTTTGCTCAG 
GGCCTTCCGA CCTATACACT AGCTGTCCAG GGGATTTCTG GCCTCCCACT GAAGAAACAA 
ATAGATACCA GGAAGAAGCT AAGTAAAGCA GTGGAGAAGC GCTTTCCGCA TGACAAACTC 
CTCTTGTTAG ACACTCAACA GGAGGCAGGG ATGCTGCTTA GGCAGTTGGC TAACCAGAAG 
CAACAGCATC TTGCTTTTCG AGATCGGCGG GCCTACCTAT TTGCCCATGC TGTTGATTTT 
GTTCCTAGTG AAGAGAATAA CTTGGTGGGC ACCTTGAAAA TTTCAGGCTA TGTTCGAGGG 
CAGACTCTGA ATGTCAATAG GTTGCTGCAT ATCGTTGGAT ATGGTGATTT CCAGATGAAA 
CAGATAGATG CCCCCGGAGA CCCTTTCCCT TTAAATCCTA GAGGAATTAA ACCCCAAAAG 
GACCCAGACA TGGCAATGGA GATTTGTGCT ACGGATGCTG TAGATGATAT GGAAGAAGGT 
CTTAAAGTCC TAATGAAGGC AGACCCTGGT AGACAGGAAT CCTTGCAAGC AGAGGTTATC 
CCAGATCCAA TGGAGGGAGA GCAAACCTGG CCCACTGAGG AGGAGCTGAG CGAGGCAAAG 
GATTTCTTGA AGGAAAGTTC TAAGGTGGTA AAGAAGGTCC CCAAAGGAAC ATCCAGTTAC 
CAAGCTGAAT GGATTTTGGA TGGTGGCAGC CAAAGTGGTG GGGAAGGAGA TGAATATGAA 
TATGATGATA TGGAACATGA GGATTTTATG GAGGAGGAAT CTCAGGATGA GAGTAGTGAA 
GAAGAGGAAG AATATGAAAC TATGACTATT GGGGAGTCTG TGCATGATGA TCTGTATGAT 
AAGAAAGTAG ATGAAGAAGC TGAGGCAAAA ATGTTGGAGA AATATAAACA AGAAAGACTG 
GAAGAGATGT TTCCAGATGA AGTGGACACG CCCCGTGATG TGGCTGCTCG AATTCGATTT 
CAGAAATACA GAGGCCTTAA GAGCTTCCGG ACATCTCCAT GGGATCCTAA GGAAAACCTT 
CCTCAAGATT ATGCTCGAAT ATTTCAGTTT CAGAACTTTA CTAACACTAG GAAAAGCATC 
TTTAAAGAGG TTGAAGAAAA AGAGGTTGAA GGAGCTGAGG TTGGCTGGTA TGTCACACTT 
CATGTCTCTG AAGTCCCCGT CTCAGTGGTC GAGTGCTTCA GGCAAGGAAC ACCCTTGATT 
GCATTTTCTT TACTACCTCA TGAACAGAAG ATGTCAGTAT TGAATATGGT GGTGAGGCGT 
GACCCTGGCA ACACTGAACC TGTGAAAGCC AAGGAAGAGC TCATATTTCA CTGTGGATTC 
AGGCGCTTCC GAGCCTCACC TTTATTCTCT CAGCACACTG CAGCGGACAA ACATAAATTG 
CAGAGATTCC TGACTGCTGA CATGGCCCTG GTGGCGACAG TCTATGCGCC AATCACTTTT 
CCTCCTGCAT CTGTGCTGCT TTTCAAGCAA AAAAGCAATG GAATGCACAG CCTCATTGCT 
ACAGGCCATC TTATGTCAGT AGATCCAGAC AGAATGGTCA TCAAGAGAGT TGTTCTGAGT 
GGTCATCCTT TCAAAATTTT TACTAAGATG GCAGTAGTAC GTTACATGTT CTTCAACAGA 
GAGGATGTGC TGTGGTTTAA ACCAGTGGAA CTGAGAACGA AGTGGGGCCG GAGAGGACAT 
ATCAAGGAAC CTTTAGGTAC CCATGGCCAC ATGAAATGCA GCTTTGATGG GAAGCTAAAA 
TCTCAAGACA CAGTACTGAT GAACCTGTAT AAACGAGTCT TCCCCAAATG GACTTATGAT 
CCATATGTAC CAGAACCAGT ACCCTGGCTG AAAAGTGAGA TTTCTTCAAC AGTGCCTCAA 
GGGGGCATGG AGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060598.3
CDS	958..3372
Translation	MAAHRPGPLKQQNKAHKGGRHRGRGSAQRDGKGRLALKTLSKKVRKELSRVDQRHRASQLRKQKKEAVLAEKRQLGGKDGPPHQVLVVPLHSRISLPEAMQLLQDRDTGTVHLNELGNTQNFMLLCPRLKHRWFFTSARPGDLHVVLDMAKVADTILFLLDPLEGWDSTGDYCLSCLFAQGLPTYTLAVQGISGLPLKKQIDTRKKLSKAVEKRFPHDKLLLLDTQQEAGMLLRQLANQKQQHLAFRDRRAYLFAHAVDFVPSEENNLVGTLKISGYVRGQTLNVNRLLHIVGYGDFQMKQIDAPGDPFPLNPRGIKPQKDPDMAMEICATDAVDDMEEGLKVLMKADPGRQESLQAEVIPDPMEGEQTWPTEEELSEAKDFLKESSKVVKKVPKGTSSYQAEWILDGGSQSGGEGDEYEYDDMEHEDFMEEESQDESSEEEEEYETMTIGESVHDDLYDKKVDEEAEAKMLEKYKQERLEEMFPDEVDTPRDVAARIRFQKYRGLKSFRTSPWDPKENLPQDYARIFQFQNFTNTRKSIFKEVEEKEVEGAEVGWYVTLHVSEVPVSVVECFRQGTPLIAFSLLPHEQKMSVLNMVVRRDPGNTEPVKAKEELIFHCGFRRFRASPLFSQHTAADKHKLQRFLTADMALVATVYAPITFPPASVLLFKQKSNGMHSLIATGHLMSVDPDRMVIKRVVLSGHPFKIFTKMAVVRYMFFNREDVLWFKPVELRTKWGRRGHIKEPLGTHGHMKCSFDGKLKSQDTVLMNLYKRVFPKWTYDPYVPEPVPWLKSEISSTVPQGGME

Target ORF information:

RefSeq Version	NM_018128.4
Organism	Homo sapiens(human)
Definition	Homo sapiens TSR1 ribosome maturation factor (TSR1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018128.4

ORF Insert Sequence:

ATGGCGGCCC ACCGCCCCGG CCCGCTCAAG CAGCAGAATA AAGCTCATAA AGGCGGACGG 
CATCGGGGTC GGGGATCTGC ACAGCGGGAC GGCAAGGGCC GTCTGGCACT GAAAACCCTA 
AGCAAGAAGG TGAGAAAAGA ACTCAGCAGA GTCGACCAGA GGCATCGCGC CAGCCAGCTC 
CGAAAGCAGA AGAAGGAGGC GGTTCTGGCA GAGAAGAGAC AGCTGGGTGG CAAGGATGGC 
CCTCCTCATC AGGTACTGGT GGTGCCCCTG CACAGCAGAA TTTCCCTGCC AGAGGCCATG 
CAGCTGCTTC AAGATAGGGA CACTGGAACA GTACACTTGA ATGAATTGGG AAACACCCAG 
AACTTTATGC TGCTGTGCCC CCGCTTGAAA CATCGGTGGT TTTTCACCTC AGCAAGGCCA 
GGGGATCTGC ACGTTGTGTT AGACATGGCT AAAGTAGCTG ATACCATCCT GTTCCTCCTT 
GATCCACTAG AAGGCTGGGA CAGCACCGGT GATTACTGTC TTTCCTGCCT CTTTGCTCAG 
GGCCTTCCGA CCTATACACT AGCTGTCCAG GGGATTTCTG GCCTCCCACT GAAGAAACAA 
ATAGATACCA GGAAGAAGCT AAGTAAAGCA GTGGAGAAGC GCTTTCCGCA TGACAAACTC 
CTCTTGTTAG ACACTCAACA GGAGGCAGGG ATGCTGCTTA GGCAGTTGGC TAACCAGAAG 
CAACAGCATC TTGCTTTTCG AGATCGGCGG GCCTACCTAT TTGCCCATGC TGTTGATTTT 
GTTCCTAGTG AAGAGAATAA CTTGGTGGGC ACCTTGAAAA TTTCAGGCTA TGTTCGAGGG 
CAGACTCTGA ATGTCAATAG GTTGCTGCAT ATCGTTGGAT ATGGTGATTT CCAGATGAAA 
CAGATAGATG CCCCCGGAGA CCCTTTCCCT TTAAATCCTA GAGGAATTAA ACCCCAAAAG 
GACCCAGACA TGGCAATGGA GATTTGTGCT ACGGATGCTG TAGATGATAT GGAAGAAGGT 
CTTAAAGTCC TAATGAAGGC AGACCCTGGT AGACAGGAAT CCTTGCAAGC AGAGGTTATC 
CCAGATCCAA TGGAGGGAGA GCAAACCTGG CCCACTGAGG AGGAGCTGAG CGAGGCAAAG 
GATTTCTTGA AGGAAAGTTC TAAGGTGGTA AAGAAGGTCC CCAAAGGAAC ATCCAGTTAC 
CAAGCTGAAT GGATTTTGGA TGGTGGCAGC CAAAGTGGTG GGGAAGGAGA TGAATATGAA 
TATGATGATA TGGAACATGA GGATTTTATG GAGGAGGAAT CTCAGGATGA GAGTAGTGAA 
GAAGAGGAAG AATATGAAAC TATGACTATT GGGGAGTCTG TGCATGATGA TCTGTATGAT 
AAGAAAGTAG ATGAAGAAGC TGAGGCAAAA ATGTTGGAGA AATATAAACA AGAAAGACTG 
GAAGAGATGT TTCCAGATGA AGTGGACACG CCCCGTGATG TGGCTGCTCG AATTCGATTT 
CAGAAATACA GAGGCCTTAA GAGCTTCCGG ACATCTCCAT GGGATCCTAA GGAAAACCTT 
CCTCAAGATT ATGCTCGAAT ATTTCAGTTT CAGAACTTTA CTAACACTAG GAAAAGCATC 
TTTAAAGAGG TTGAAGAAAA AGAGGTTGAA GGAGCTGAGG TTGGCTGGTA TGTCACACTT 
CATGTCTCTG AAGTCCCCGT CTCAGTGGTC GAGTGCTTCA GGCAAGGAAC ACCCTTGATT 
GCATTTTCTT TACTACCTCA TGAACAGAAG ATGTCAGTAT TGAATATGGT GGTGAGGCGT 
GACCCTGGCA ACACTGAACC TGTGAAAGCC AAGGAAGAGC TCATATTTCA CTGTGGATTC 
AGGCGCTTCC GAGCCTCACC TTTATTCTCT CAGCACACTG CAGCGGACAA ACATAAATTG 
CAGAGATTCC TGACTGCTGA CATGGCCCTG GTGGCGACAG TCTATGCGCC AATCACTTTT 
CCTCCTGCAT CTGTGCTGCT TTTCAAGCAA AAAAGCAATG GAATGCACAG CCTCATTGCT 
ACAGGCCATC TTATGTCAGT AGATCCAGAC AGAATGGTCA TCAAGAGAGT TGTTCTGAGT 
GGTCATCCTT TCAAAATTTT TACTAAGATG GCAGTAGTAC GTTACATGTT CTTCAACAGA 
GAGGATGTGC TGTGGTTTAA ACCAGTGGAA CTGAGAACGA AGTGGGGCCG GAGAGGACAT 
ATCAAGGAAC CTTTAGGTAC CCATGGCCAC ATGAAATGCA GCTTTGATGG GAAGCTAAAA 
TCTCAAGACA CAGTACTGAT GAACCTGTAT AAACGAGTCT TCCCCAAATG GACTTATGAT 
CCATATGTAC CAGAACCAGT ACCCTGGCTG AAAAGTGAGA TTTCTTCAAC AGTGCCTCAA 
GGGGGCATGG AGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TSR1 ( NM_018128.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_060598.3 Homo sapiens TSR1 ribosome maturation factor (TSR1), mRNA.

Price & Availability↑

CloneID	OHu02946
Clone ID Related Accession (Same CDS sequence)	NM_018128.4 , NM_018128.5
Accession Version	NM_018128.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2415bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-14
Organism	Homo sapiens(human)
Product	pre-rRNA-processing protein TSR1 homolog
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL450226.1. On Aug 2, 2019 this sequence version replaced NM_018128.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.276926.1, SRR1660807.186066.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGGCCC ACCGCCCCGG CCCGCTCAAG CAGCAGAATA AAGCTCATAA AGGCGGACGG 
CATCGGGGTC GGGGATCTGC ACAGCGGGAC GGCAAGGGCC GTCTGGCACT GAAAACCCTA 
AGCAAGAAGG TGAGAAAAGA ACTCAGCAGA GTCGACCAGA GGCATCGCGC CAGCCAGCTC 
CGAAAGCAGA AGAAGGAGGC GGTTCTGGCA GAGAAGAGAC AGCTGGGTGG CAAGGATGGC 
CCTCCTCATC AGGTACTGGT GGTGCCCCTG CACAGCAGAA TTTCCCTGCC AGAGGCCATG 
CAGCTGCTTC AAGATAGGGA CACTGGAACA GTACACTTGA ATGAATTGGG AAACACCCAG 
AACTTTATGC TGCTGTGCCC CCGCTTGAAA CATCGGTGGT TTTTCACCTC AGCAAGGCCA 
GGGGATCTGC ACGTTGTGTT AGACATGGCT AAAGTAGCTG ATACCATCCT GTTCCTCCTT 
GATCCACTAG AAGGCTGGGA CAGCACCGGT GATTACTGTC TTTCCTGCCT CTTTGCTCAG 
GGCCTTCCGA CCTATACACT AGCTGTCCAG GGGATTTCTG GCCTCCCACT GAAGAAACAA 
ATAGATACCA GGAAGAAGCT AAGTAAAGCA GTGGAGAAGC GCTTTCCGCA TGACAAACTC 
CTCTTGTTAG ACACTCAACA GGAGGCAGGG ATGCTGCTTA GGCAGTTGGC TAACCAGAAG 
CAACAGCATC TTGCTTTTCG AGATCGGCGG GCCTACCTAT TTGCCCATGC TGTTGATTTT 
GTTCCTAGTG AAGAGAATAA CTTGGTGGGC ACCTTGAAAA TTTCAGGCTA TGTTCGAGGG 
CAGACTCTGA ATGTCAATAG GTTGCTGCAT ATCGTTGGAT ATGGTGATTT CCAGATGAAA 
CAGATAGATG CCCCCGGAGA CCCTTTCCCT TTAAATCCTA GAGGAATTAA ACCCCAAAAG 
GACCCAGACA TGGCAATGGA GATTTGTGCT ACGGATGCTG TAGATGATAT GGAAGAAGGT 
CTTAAAGTCC TAATGAAGGC AGACCCTGGT AGACAGGAAT CCTTGCAAGC AGAGGTTATC 
CCAGATCCAA TGGAGGGAGA GCAAACCTGG CCCACTGAGG AGGAGCTGAG CGAGGCAAAG 
GATTTCTTGA AGGAAAGTTC TAAGGTGGTA AAGAAGGTCC CCAAAGGAAC ATCCAGTTAC 
CAAGCTGAAT GGATTTTGGA TGGTGGCAGC CAAAGTGGTG GGGAAGGAGA TGAATATGAA 
TATGATGATA TGGAACATGA GGATTTTATG GAGGAGGAAT CTCAGGATGA GAGTAGTGAA 
GAAGAGGAAG AATATGAAAC TATGACTATT GGGGAGTCTG TGCATGATGA TCTGTATGAT 
AAGAAAGTAG ATGAAGAAGC TGAGGCAAAA ATGTTGGAGA AATATAAACA AGAAAGACTG 
GAAGAGATGT TTCCAGATGA AGTGGACACG CCCCGTGATG TGGCTGCTCG AATTCGATTT 
CAGAAATACA GAGGCCTTAA GAGCTTCCGG ACATCTCCAT GGGATCCTAA GGAAAACCTT 
CCTCAAGATT ATGCTCGAAT ATTTCAGTTT CAGAACTTTA CTAACACTAG GAAAAGCATC 
TTTAAAGAGG TTGAAGAAAA AGAGGTTGAA GGAGCTGAGG TTGGCTGGTA TGTCACACTT 
CATGTCTCTG AAGTCCCCGT CTCAGTGGTC GAGTGCTTCA GGCAAGGAAC ACCCTTGATT 
GCATTTTCTT TACTACCTCA TGAACAGAAG ATGTCAGTAT TGAATATGGT GGTGAGGCGT 
GACCCTGGCA ACACTGAACC TGTGAAAGCC AAGGAAGAGC TCATATTTCA CTGTGGATTC 
AGGCGCTTCC GAGCCTCACC TTTATTCTCT CAGCACACTG CAGCGGACAA ACATAAATTG 
CAGAGATTCC TGACTGCTGA CATGGCCCTG GTGGCGACAG TCTATGCGCC AATCACTTTT 
CCTCCTGCAT CTGTGCTGCT TTTCAAGCAA AAAAGCAATG GAATGCACAG CCTCATTGCT 
ACAGGCCATC TTATGTCAGT AGATCCAGAC AGAATGGTCA TCAAGAGAGT TGTTCTGAGT 
GGTCATCCTT TCAAAATTTT TACTAAGATG GCAGTAGTAC GTTACATGTT CTTCAACAGA 
GAGGATGTGC TGTGGTTTAA ACCAGTGGAA CTGAGAACGA AGTGGGGCCG GAGAGGACAT 
ATCAAGGAAC CTTTAGGTAC CCATGGCCAC ATGAAATGCA GCTTTGATGG GAAGCTAAAA 
TCTCAAGACA CAGTACTGAT GAACCTGTAT AAACGAGTCT TCCCCAAATG GACTTATGAT 
CCATATGTAC CAGAACCAGT ACCCTGGCTG AAAAGTGAGA TTTCTTCAAC AGTGCCTCAA 
GGGGGCATGG AGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060598.3
CDS	31..2445
Translation	MAAHRPGPLKQQNKAHKGGRHRGRGSAQRDGKGRLALKTLSKKVRKELSRVDQRHRASQLRKQKKEAVLAEKRQLGGKDGPPHQVLVVPLHSRISLPEAMQLLQDRDTGTVHLNELGNTQNFMLLCPRLKHRWFFTSARPGDLHVVLDMAKVADTILFLLDPLEGWDSTGDYCLSCLFAQGLPTYTLAVQGISGLPLKKQIDTRKKLSKAVEKRFPHDKLLLLDTQQEAGMLLRQLANQKQQHLAFRDRRAYLFAHAVDFVPSEENNLVGTLKISGYVRGQTLNVNRLLHIVGYGDFQMKQIDAPGDPFPLNPRGIKPQKDPDMAMEICATDAVDDMEEGLKVLMKADPGRQESLQAEVIPDPMEGEQTWPTEEELSEAKDFLKESSKVVKKVPKGTSSYQAEWILDGGSQSGGEGDEYEYDDMEHEDFMEEESQDESSEEEEEYETMTIGESVHDDLYDKKVDEEAEAKMLEKYKQERLEEMFPDEVDTPRDVAARIRFQKYRGLKSFRTSPWDPKENLPQDYARIFQFQNFTNTRKSIFKEVEEKEVEGAEVGWYVTLHVSEVPVSVVECFRQGTPLIAFSLLPHEQKMSVLNMVVRRDPGNTEPVKAKEELIFHCGFRRFRASPLFSQHTAADKHKLQRFLTADMALVATVYAPITFPPASVLLFKQKSNGMHSLIATGHLMSVDPDRMVIKRVVLSGHPFKIFTKMAVVRYMFFNREDVLWFKPVELRTKWGRRGHIKEPLGTHGHMKCSFDGKLKSQDTVLMNLYKRVFPKWTYDPYVPEPVPWLKSEISSTVPQGGME

Target ORF information:

RefSeq Version	NM_018128.5
Organism	Homo sapiens(human)
Definition	Homo sapiens TSR1 ribosome maturation factor (TSR1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018128.5

ORF Insert Sequence:

ATGGCGGCCC ACCGCCCCGG CCCGCTCAAG CAGCAGAATA AAGCTCATAA AGGCGGACGG 
CATCGGGGTC GGGGATCTGC ACAGCGGGAC GGCAAGGGCC GTCTGGCACT GAAAACCCTA 
AGCAAGAAGG TGAGAAAAGA ACTCAGCAGA GTCGACCAGA GGCATCGCGC CAGCCAGCTC 
CGAAAGCAGA AGAAGGAGGC GGTTCTGGCA GAGAAGAGAC AGCTGGGTGG CAAGGATGGC 
CCTCCTCATC AGGTACTGGT GGTGCCCCTG CACAGCAGAA TTTCCCTGCC AGAGGCCATG 
CAGCTGCTTC AAGATAGGGA CACTGGAACA GTACACTTGA ATGAATTGGG AAACACCCAG 
AACTTTATGC TGCTGTGCCC CCGCTTGAAA CATCGGTGGT TTTTCACCTC AGCAAGGCCA 
GGGGATCTGC ACGTTGTGTT AGACATGGCT AAAGTAGCTG ATACCATCCT GTTCCTCCTT 
GATCCACTAG AAGGCTGGGA CAGCACCGGT GATTACTGTC TTTCCTGCCT CTTTGCTCAG 
GGCCTTCCGA CCTATACACT AGCTGTCCAG GGGATTTCTG GCCTCCCACT GAAGAAACAA 
ATAGATACCA GGAAGAAGCT AAGTAAAGCA GTGGAGAAGC GCTTTCCGCA TGACAAACTC 
CTCTTGTTAG ACACTCAACA GGAGGCAGGG ATGCTGCTTA GGCAGTTGGC TAACCAGAAG 
CAACAGCATC TTGCTTTTCG AGATCGGCGG GCCTACCTAT TTGCCCATGC TGTTGATTTT 
GTTCCTAGTG AAGAGAATAA CTTGGTGGGC ACCTTGAAAA TTTCAGGCTA TGTTCGAGGG 
CAGACTCTGA ATGTCAATAG GTTGCTGCAT ATCGTTGGAT ATGGTGATTT CCAGATGAAA 
CAGATAGATG CCCCCGGAGA CCCTTTCCCT TTAAATCCTA GAGGAATTAA ACCCCAAAAG 
GACCCAGACA TGGCAATGGA GATTTGTGCT ACGGATGCTG TAGATGATAT GGAAGAAGGT 
CTTAAAGTCC TAATGAAGGC AGACCCTGGT AGACAGGAAT CCTTGCAAGC AGAGGTTATC 
CCAGATCCAA TGGAGGGAGA GCAAACCTGG CCCACTGAGG AGGAGCTGAG CGAGGCAAAG 
GATTTCTTGA AGGAAAGTTC TAAGGTGGTA AAGAAGGTCC CCAAAGGAAC ATCCAGTTAC 
CAAGCTGAAT GGATTTTGGA TGGTGGCAGC CAAAGTGGTG GGGAAGGAGA TGAATATGAA 
TATGATGATA TGGAACATGA GGATTTTATG GAGGAGGAAT CTCAGGATGA GAGTAGTGAA 
GAAGAGGAAG AATATGAAAC TATGACTATT GGGGAGTCTG TGCATGATGA TCTGTATGAT 
AAGAAAGTAG ATGAAGAAGC TGAGGCAAAA ATGTTGGAGA AATATAAACA AGAAAGACTG 
GAAGAGATGT TTCCAGATGA AGTGGACACG CCCCGTGATG TGGCTGCTCG AATTCGATTT 
CAGAAATACA GAGGCCTTAA GAGCTTCCGG ACATCTCCAT GGGATCCTAA GGAAAACCTT 
CCTCAAGATT ATGCTCGAAT ATTTCAGTTT CAGAACTTTA CTAACACTAG GAAAAGCATC 
TTTAAAGAGG TTGAAGAAAA AGAGGTTGAA GGAGCTGAGG TTGGCTGGTA TGTCACACTT 
CATGTCTCTG AAGTCCCCGT CTCAGTGGTC GAGTGCTTCA GGCAAGGAAC ACCCTTGATT 
GCATTTTCTT TACTACCTCA TGAACAGAAG ATGTCAGTAT TGAATATGGT GGTGAGGCGT 
GACCCTGGCA ACACTGAACC TGTGAAAGCC AAGGAAGAGC TCATATTTCA CTGTGGATTC 
AGGCGCTTCC GAGCCTCACC TTTATTCTCT CAGCACACTG CAGCGGACAA ACATAAATTG 
CAGAGATTCC TGACTGCTGA CATGGCCCTG GTGGCGACAG TCTATGCGCC AATCACTTTT 
CCTCCTGCAT CTGTGCTGCT TTTCAAGCAA AAAAGCAATG GAATGCACAG CCTCATTGCT 
ACAGGCCATC TTATGTCAGT AGATCCAGAC AGAATGGTCA TCAAGAGAGT TGTTCTGAGT 
GGTCATCCTT TCAAAATTTT TACTAAGATG GCAGTAGTAC GTTACATGTT CTTCAACAGA 
GAGGATGTGC TGTGGTTTAA ACCAGTGGAA CTGAGAACGA AGTGGGGCCG GAGAGGACAT 
ATCAAGGAAC CTTTAGGTAC CCATGGCCAC ATGAAATGCA GCTTTGATGG GAAGCTAAAA 
TCTCAAGACA CAGTACTGAT GAACCTGTAT AAACGAGTCT TCCCCAAATG GACTTATGAT 
CCATATGTAC CAGAACCAGT ACCCTGGCTG AAAAGTGAGA TTTCTTCAAC AGTGCCTCAA 
GGGGGCATGG AGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Biological insights from 108 schizophrenia-associated genetic loci.
Nature511(7510)421-7(2014 Jul)

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Cell149(6)1393-406(2012 Jun)
Castello A,Fischer B,Eichelbaum K,Horos R,Beckmann BM,Strein C,Davey NE,Humphreys DT,Preiss T,Steinmetz LM,Krijgsveld J,Hentze MW

Analysis of two human pre-ribosomal factors, bystin and hTsr1, highlights differences in evolution of ribosome biogenesis between yeast and mammals.
Nucleic acids research39(1)280-91(2011 Jan)
Carron C,O'Donohue MF,Choesmel V,Faubladier M,Gleizes PE

Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data.
JAMA302(2)168-78(2009 Jul)
Vasan RS,Glazer NL,Felix JF,Lieb W,Wild PS,Felix SB,Watzinger N,Larson MG,Smith NL,Dehghan A,Grosshennig A,Schillert A,Teumer A,Schmidt R,Kathiresan S,Lumley T,Aulchenko YS,K?nig IR,Zeller T,Homuth G,Struchalin M,Aragam J,Bis JC,Rivadeneira F,Erdmann J,Schnabel RB,D?rr M,Zweiker R,Lind L,Rodeheffer RJ,Greiser KH,Levy D,Haritunians T,Deckers JW,Stritzke J,Lackner KJ,V?lker U,Ingelsson E,Kullo I,Haerting J,O'Donnell CJ,Heckbert SR,Stricker BH,Ziegler A,Reffelmann T,Redfield MM,Werdan K,Mitchell GF,Rice K,Arnett DK,Hofman A,Gottdiener JS,Uitterlinden AG,Meitinger T,Blettner M,Friedrich N,Wang TJ,Psaty BM,van Duijn CM,Wichmann HE,Munzel TF,Kroemer HK,Benjamin EJ,Rotter JI,Witteman JC,Schunkert H,Schmidt H,V?lzke H,Blankenberg S

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TSR1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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