IPO9 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	IPO9
Entrez Gene ID	55705
Full Name	importin 9
Synonyms	Imp9
General protein information	Preferred Names importin 9 Names importin-9 ran-binding protein 9 ranBP9
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1q32.1

mRNA and Protein(s)

mRNA	Protein	Name
NM_018085.5	NP_060555.2	importin-9
NM_018085.4	NP_060555.2	importin-9

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	IPO9	XP_419247.3
Bos taurus (cattle)	IPO9	XP_003587144.2
Xenopus tropicalis (tropical clawed frog)	ipo9	NP_001090647.1
	IPO9	XP_001108417.1
Rattus norvegicus (Norway rat)	Ipo9	NP_001100650.1
Danio rerio (zebrafish)	ipo9	NP_998704.1
Drosophila melanogaster (fruit fly)	Ranbp9	NP_650068.1
Homo sapiens (human)	IPO9	NP_060555.2
Canis lupus familiaris (dog)	IPO9	XP_005622251.1
Mus musculus (house mouse)	Ipo9	NP_722469.1
Arabidopsis thaliana (thale cress)	AT1G26170	NP_173942.2
Pan troglodytes (chimpanzee)	IPO9	XP_514097.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP011156	XP_309493.3

Gene Ontology
Bibliography

Related articles in PubMed

Downregulation of importin-9 protects MCF-7 cells against apoptosis induced by the combination of garlic-derived alliin and paclitaxel.
Izdebska M, Grzanka D, Gagat M, Ha?as-Wi?niewska M, Grzanka A
Oncology reports35(5)3084-93(2016 May)

Novel role for molecular transporter importin 9 in posttranscriptional regulation of IFN-? expression.
Matsumiya T, Xing F, Ebina M, Hayakari R, Imaizumi T, Yoshida H, Kikuchi H, Topham MK, Satoh K, Stafforini DM
Journal of immunology (Baltimore, Md. : 1950)191(4)1907-15(2013 Aug)

Defining the membrane proteome of NK cells.
Ghosh D, Lippert D, Krokhin O, Cortens JP, Wilkins JA
Journal of mass spectrometry : JMS45(1)1-25(2010 Jan)

Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach.
Koch HB, Zhang R, Verdoodt B, Bailey A, Zhang CD, Yates JR 3rd, Menssen A, Hermeking H
Cell cycle (Georgetown, Tex.)6(2)205-17(2007 Jan)

Inhibition of nuclear import by the proapoptotic protein CC3.
King FW, Shtivelman E
Molecular and cellular biology24(16)7091-101(2004 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

CFL1 itself does not translocate actin into the cell nucleus but this transport requires the functional expression of IPO9.
Title: Downregulation of importin-9 protects MCF-7 cells against apoptosis induced by the combination of garlic-derived alliin and paclitaxel.

IPO9 associates with 2 stable stem-loop structures of the IFN-epsilon 5'UTR. IPO9 overexpression decreased, and IPO9 silencing increased basal IFN-epsilon expression.
Title: Novel role for molecular transporter importin 9 in posttranscriptional regulation of IFN-? expression.

specific interaction between a member of the importin beta/karyopherin beta superfamily, importin 9, and the A subunit of PP2A (PR65)
Title: Interaction between protein phosphatase 2A and members of the importin beta superfamily.

The following IPO9 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IPO9 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu13394	NM_018085.5 Latest version!	Homo sapiens importin 9 (IPO9), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$734.30 $1049.00
View Old Accession Versions >>
OHu13394	NM_018085.4	Homo sapiens importin 9 (IPO9), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$734.30 $1049.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

IPO9 ( NM_018085.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_060555.2 Homo sapiens importin 9 (IPO9), mRNA.

Price & Availability↑

CloneID	OHu13394
Clone ID Related Accession (Same CDS sequence)	NM_018085.5 , NM_018085.4
Accession Version	NM_018085.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3126bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-05
Organism	Homo sapiens(human)
Product	importin-9
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL645504.10, DB232332.1, DA861528.1, AF410465.1 and AL513217.11. On Nov 23, 2018 this sequence version replaced NM_018085.4. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.156909.1, SRR1803613.200236.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000361565.9/ ENSP00000354742.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGGCGG CGGCGGCAGC TGGTGCGGCC TCCGGGCTGC CGGGTCCAGT GGCACAAGGA 
TTAAAGGAAG CGTTAGTGGA TACGCTCACC GGGATCCTAT CCCCAGTACA GGAGGTGCGG 
GCGGCTGCTG AAGAACAGAT TAAGGTGCTG GAGGTGACGG AGGAATTTGG TGTTCACTTG 
GCAGAACTGA CTGTAGATCC CCAGGGGGCA CTGGCAATCC GTCAGCTGGC ATCAGTCATC 
TTGAAACAAT ATGTGGAGAC TCACTGGTGT GCCCAATCAG AGAAATTTAG GCCTCCTGAA 
ACTACAGAAA GGGCAAAAAT TGTTATCCGG GAGCTATTGC CTAATGGGTT GAGAGAATCG 
ATAAGCAAAG TGCGCTCCAG TGTGGCCTAT GCAGTGTCAG CCATTGCCCA CTGGGACTGG 
CCTGAAGCTT GGCCCCAACT CTTCAACCTG CTCATGGAGA TGTTGGTGAG CGGAGACTTA 
AATGCCGTCC ATGGAGCCAT GCGTGTGCTG ACAGAATTCA CTCGTGAAGT AACAGACACA 
CAGATGCCAC TTGTTGCTCC TGTCATTCTC CCAGAGATGT ATAAGATCTT CACCATGGCT 
GAGGTGTATG GTATTCGAAC CCGTTCCCGA GCCGTGGAGA TTTTTACCAC TTGTGCCCAT 
ATGATCTGTA ACATGGAGGA GCTGGAAAAG GGTGCAGCCA AAGTCCTGAT CTTTCCCGTG 
GTACAGCAGT TCACAGAGGC CTTTGTTCAG GCCCTCCAGA TACCAGATGG CCCCACATCT 
GACAGTGGGT TTAAGATGGA GGTCCTAAAG GCAGTGACAG CCCTAGTGAA AAACTTCCCA 
AAGCACATGG TGTCCTCCAT GCAGCAGATT CTGCCTATTG TTTGGAACAC CCTAACCGAG 
AGTGCAGCTT TTTATGTGAG GACAGAAGTA AATTACACAG AAGAAGTAGA AGATCCTGTG 
GATTCTGATG GTGAAGTCCT GGGCTTTGAA AATCTCGTCT TTAGCATTTT TGAATTTGTC 
CATGCTCTAC TAGAAAATAG CAAATTCAAA AGCACTGTTA AGAAAGCCTT GCCTGAATTG 
ATTTATTATA TTATCCTGTA CATGCAAATC ACTGAGGAGC AGATTAAAGT ATGGACAGCC 
AACCCCCAAC AATTTGTAGA AGATGAAGAT GATGATACAT TCTCCTATAC TGTTAGAATA 
GCAGCTCAAG ACTTGTTGCT GGCTGTGGCC ACAGATTTCC AGAATGAAAG TGCAGCAGCC 
CTGGCTGCTG CAGCCACTCG ACATTTACAA GAAGCTGAGC AAACCAAAAA CAGTGGCACT 
GAGCACTGGT GGAAGATCCA TGAGGCATGC ATGCTTGCCC TAGGCTCAGT GAAGGCCATC 
ATCACTGACA GTGTGAAAAA TGGCAGGATT CATTTTGACA TGCATGGGTT CCTGACCAAT 
GTCATCCTTG CAGACCTCAA CCTCTCAGTG TCTCCTTTCC TCTTGGGCCG GGCACTTTGG 
GCTGCCAGTC GGTTCACTGT TGCTATGTCC CCTGAACTGA TCCAGCAGTT CCTACAGGCA 
ACAGTTAGTG GTCTTCACGA GACACAGCCC CCATCAGTTC GAATTTCTGC AGTGAGAGCC 
ATCTGGGGTT ATTGTGACCA ACTGAAAGTC TCAGAGAGTA CCCACGTGCT CCAGCCCTTC 
CTCCCCAGCA TCCTTGATGG CTTAATTCAC CTAGCAGCCC AGTTCAGCTC AGAGGTCCTC 
AACCTGGTGA TGGAGACCCT GTGCATCGTT TGTACAGTAG ACCCCGAATT CACAGCAAGC 
ATGGAAAGCA AAATCTGCCC CTTCACCATC GCCATTTTCC TAAAGTACAG TAATGATCCC 
GTCGTCGCCT CACTGGCTCA GGACATCTTC AAGGAGCTGT CCCAGATTGA AGCCTGTCAG 
GGCCCAATGC AAATGAGGCT GATTCCCACT CTGGTCAGCA TAATGCAGGC CCCAGCAGAC 
AAGATTCCTG CAGGGCTTTG TGCGACAGCC ATTGATATCC TGACAACAGT AGTACGAAAT 
ACAAAGCCTC CCCTTTCCCA GCTTCTCATC TGCCAAGCTT TCCCTGCTGT GGCACAGTGT 
ACCCTTCACA CAGATGACAA TGCCACCATG CAGAATGGCG GAGAGTGCTT GCGGGCCTAT 
GTGTCAGTGA CCCTGGAACA AGTAGCCCAG TGGCATGATG AGCAGGGCCA CAATGGACTG 
TGGTATGTGA TGCAAGTGGT GAGCCAGCTC CTGGACCCCC GCACCTCAGA GTTCACTGCG 
GCCTTTGTGG GCCGCCTTGT TTCCACCCTC ATCTCCAAGG CAGGGCGGGA ACTCGGGGAG 
AATCTAGACC AGATTCTTCG TGCCATCCTC AGTAAGATGC AGCAGGCAGA GACGCTCAGT 
GTCATGCAGT CCCTGATCAT GGTGTTCGCT CATCTGGTGC ACACTCAGCT AGAACCTCTC 
TTGGAGTTCC TGTGTAGCCT CCCAGGACCT ACTGGCAAAC CTGCTCTAGA GTTTGTGATG 
GCTGAGTGGA CAAGCCGACA GCACCTGTTC TATGGACAGT ATGAAGGCAA AGTCAGCTCT 
GTGGCACTCT GTAAGCTGCT CCAGCATGGC ATCAATGCAG ATGACAAACG GCTACAGGAT 
ATCCGTGTGA AGGGAGAGGA GATCTACAGC ATGGATGAGG GCATCCGCAC CCGCTCTAAG 
TCAGCCAAAA ACCCAGAACG CTGGACAAAC ATTCCTTTGC TGGTCAAGAT CCTAAAGCTG 
ATCATCAACG AGCTCTCCAA CGTCATGGAG GCTAATGCCG CTCGCCAGGC CACTCCTGCA 
GAGTGGAGTC AAGATGACTC CAATGATATG TGGGAGGACC AGGAGGAGGA AGAGGAGGAG 
GAGGAGGATG GTTTAGCTGG CCAACTTTTA TCTGACATTC TTGCTACAAG TAAATATGAG 
GAGGATTACT ACGAGGATGA TGAGGAAGAT GACCCTGATG CCCTGAAGGA TCCTCTCTAT 
CAGATTGATC TGCAGGCATA TCTCACAGAT TTCCTCTGCC AGTTTGCTCA GCAGCCCTGC 
TACATAATGT TTTCAGGCCA CCTTAATGAC AATGAGAGGC GAGTTCTACA GACCATCGGC 
ATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060555.2
CDS	54..3179
Translation	MAAAAAAGAASGLPGPVAQGLKEALVDTLTGILSPVQEVRAAAEEQIKVLEVTEEFGVHLAELTVDPQGALAIRQLASVILKQYVETHWCAQSEKFRPPETTERAKIVIRELLPNGLRESISKVRSSVAYAVSAIAHWDWPEAWPQLFNLLMEMLVSGDLNAVHGAMRVLTEFTREVTDTQMPLVAPVILPEMYKIFTMAEVYGIRTRSRAVEIFTTCAHMICNMEELEKGAAKVLIFPVVQQFTEAFVQALQIPDGPTSDSGFKMEVLKAVTALVKNFPKHMVSSMQQILPIVWNTLTESAAFYVRTEVNYTEEVEDPVDSDGEVLGFENLVFSIFEFVHALLENSKFKSTVKKALPELIYYIILYMQITEEQIKVWTANPQQFVEDEDDDTFSYTVRIAAQDLLLAVATDFQNESAAALAAAATRHLQEAEQTKNSGTEHWWKIHEACMLALGSVKAIITDSVKNGRIHFDMHGFLTNVILADLNLSVSPFLLGRALWAASRFTVAMSPELIQQFLQATVSGLHETQPPSVRISAVRAIWGYCDQLKVSESTHVLQPFLPSILDGLIHLAAQFSSEVLNLVMETLCIVCTVDPEFTASMESKICPFTIAIFLKYSNDPVVASLAQDIFKELSQIEACQGPMQMRLIPTLVSIMQAPADKIPAGLCATAIDILTTVVRNTKPPLSQLLICQAFPAVAQCTLHTDDNATMQNGGECLRAYVSVTLEQVAQWHDEQGHNGLWYVMQVVSQLLDPRTSEFTAAFVGRLVSTLISKAGRELGENLDQILRAILSKMQQAETLSVMQSLIMVFAHLVHTQLEPLLEFLCSLPGPTGKPALEFVMAEWTSRQHLFYGQYEGKVSSVALCKLLQHGINADDKRLQDIRVKGEEIYSMDEGIRTRSKSAKNPERWTNIPLLVKILKLIINELSNVMEANAARQATPAEWSQDDSNDMWEDQEEEEEEEEDGLAGQLLSDILATSKYEEDYYEDDEEDDPDALKDPLYQIDLQAYLTDFLCQFAQQPCYIMFSGHLNDNERRVLQTIGI

Target ORF information:

RefSeq Version	NM_018085.5
Organism	Homo sapiens(human)
Definition	Homo sapiens importin 9 (IPO9), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018085.5

ORF Insert Sequence:

ATGGCGGCGG CGGCGGCAGC TGGTGCGGCC TCCGGGCTGC CGGGTCCAGT GGCACAAGGA 
TTAAAGGAAG CGTTAGTGGA TACGCTCACC GGGATCCTAT CCCCAGTACA GGAGGTGCGG 
GCGGCTGCTG AAGAACAGAT TAAGGTGCTG GAGGTGACGG AGGAATTTGG TGTTCACTTG 
GCAGAACTGA CTGTAGATCC CCAGGGGGCA CTGGCAATCC GTCAGCTGGC ATCAGTCATC 
TTGAAACAAT ATGTGGAGAC TCACTGGTGT GCCCAATCAG AGAAATTTAG GCCTCCTGAA 
ACTACAGAAA GGGCAAAAAT TGTTATCCGG GAGCTATTGC CTAATGGGTT GAGAGAATCG 
ATAAGCAAAG TGCGCTCCAG TGTGGCCTAT GCAGTGTCAG CCATTGCCCA CTGGGACTGG 
CCTGAAGCTT GGCCCCAACT CTTCAACCTG CTCATGGAGA TGTTGGTGAG CGGAGACTTA 
AATGCCGTCC ATGGAGCCAT GCGTGTGCTG ACAGAATTCA CTCGTGAAGT AACAGACACA 
CAGATGCCAC TTGTTGCTCC TGTCATTCTC CCAGAGATGT ATAAGATCTT CACCATGGCT 
GAGGTGTATG GTATTCGAAC CCGTTCCCGA GCCGTGGAGA TTTTTACCAC TTGTGCCCAT 
ATGATCTGTA ACATGGAGGA GCTGGAAAAG GGTGCAGCCA AAGTCCTGAT CTTTCCCGTG 
GTACAGCAGT TCACAGAGGC CTTTGTTCAG GCCCTCCAGA TACCAGATGG CCCCACATCT 
GACAGTGGGT TTAAGATGGA GGTCCTAAAG GCAGTGACAG CCCTAGTGAA AAACTTCCCA 
AAGCACATGG TGTCCTCCAT GCAGCAGATT CTGCCTATTG TTTGGAACAC CCTAACCGAG 
AGTGCAGCTT TTTATGTGAG GACAGAAGTA AATTACACAG AAGAAGTAGA AGATCCTGTG 
GATTCTGATG GTGAAGTCCT GGGCTTTGAA AATCTCGTCT TTAGCATTTT TGAATTTGTC 
CATGCTCTAC TAGAAAATAG CAAATTCAAA AGCACTGTTA AGAAAGCCTT GCCTGAATTG 
ATTTATTATA TTATCCTGTA CATGCAAATC ACTGAGGAGC AGATTAAAGT ATGGACAGCC 
AACCCCCAAC AATTTGTAGA AGATGAAGAT GATGATACAT TCTCCTATAC TGTTAGAATA 
GCAGCTCAAG ACTTGTTGCT GGCTGTGGCC ACAGATTTCC AGAATGAAAG TGCAGCAGCC 
CTGGCTGCTG CAGCCACTCG ACATTTACAA GAAGCTGAGC AAACCAAAAA CAGTGGCACT 
GAGCACTGGT GGAAGATCCA TGAGGCATGC ATGCTTGCCC TAGGCTCAGT GAAGGCCATC 
ATCACTGACA GTGTGAAAAA TGGCAGGATT CATTTTGACA TGCATGGGTT CCTGACCAAT 
GTCATCCTTG CAGACCTCAA CCTCTCAGTG TCTCCTTTCC TCTTGGGCCG GGCACTTTGG 
GCTGCCAGTC GGTTCACTGT TGCTATGTCC CCTGAACTGA TCCAGCAGTT CCTACAGGCA 
ACAGTTAGTG GTCTTCACGA GACACAGCCC CCATCAGTTC GAATTTCTGC AGTGAGAGCC 
ATCTGGGGTT ATTGTGACCA ACTGAAAGTC TCAGAGAGTA CCCACGTGCT CCAGCCCTTC 
CTCCCCAGCA TCCTTGATGG CTTAATTCAC CTAGCAGCCC AGTTCAGCTC AGAGGTCCTC 
AACCTGGTGA TGGAGACCCT GTGCATCGTT TGTACAGTAG ACCCCGAATT CACAGCAAGC 
ATGGAAAGCA AAATCTGCCC CTTCACCATC GCCATTTTCC TAAAGTACAG TAATGATCCC 
GTCGTCGCCT CACTGGCTCA GGACATCTTC AAGGAGCTGT CCCAGATTGA AGCCTGTCAG 
GGCCCAATGC AAATGAGGCT GATTCCCACT CTGGTCAGCA TAATGCAGGC CCCAGCAGAC 
AAGATTCCTG CAGGGCTTTG TGCGACAGCC ATTGATATCC TGACAACAGT AGTACGAAAT 
ACAAAGCCTC CCCTTTCCCA GCTTCTCATC TGCCAAGCTT TCCCTGCTGT GGCACAGTGT 
ACCCTTCACA CAGATGACAA TGCCACCATG CAGAATGGCG GAGAGTGCTT GCGGGCCTAT 
GTGTCAGTGA CCCTGGAACA AGTAGCCCAG TGGCATGATG AGCAGGGCCA CAATGGACTG 
TGGTATGTGA TGCAAGTGGT GAGCCAGCTC CTGGACCCCC GCACCTCAGA GTTCACTGCG 
GCCTTTGTGG GCCGCCTTGT TTCCACCCTC ATCTCCAAGG CAGGGCGGGA ACTCGGGGAG 
AATCTAGACC AGATTCTTCG TGCCATCCTC AGTAAGATGC AGCAGGCAGA GACGCTCAGT 
GTCATGCAGT CCCTGATCAT GGTGTTCGCT CATCTGGTGC ACACTCAGCT AGAACCTCTC 
TTGGAGTTCC TGTGTAGCCT CCCAGGACCT ACTGGCAAAC CTGCTCTAGA GTTTGTGATG 
GCTGAGTGGA CAAGCCGACA GCACCTGTTC TATGGACAGT ATGAAGGCAA AGTCAGCTCT 
GTGGCACTCT GTAAGCTGCT CCAGCATGGC ATCAATGCAG ATGACAAACG GCTACAGGAT 
ATCCGTGTGA AGGGAGAGGA GATCTACAGC ATGGATGAGG GCATCCGCAC CCGCTCTAAG 
TCAGCCAAAA ACCCAGAACG CTGGACAAAC ATTCCTTTGC TGGTCAAGAT CCTAAAGCTG 
ATCATCAACG AGCTCTCCAA CGTCATGGAG GCTAATGCCG CTCGCCAGGC CACTCCTGCA 
GAGTGGAGTC AAGATGACTC CAATGATATG TGGGAGGACC AGGAGGAGGA AGAGGAGGAG 
GAGGAGGATG GTTTAGCTGG CCAACTTTTA TCTGACATTC TTGCTACAAG TAAATATGAG 
GAGGATTACT ACGAGGATGA TGAGGAAGAT GACCCTGATG CCCTGAAGGA TCCTCTCTAT 
CAGATTGATC TGCAGGCATA TCTCACAGAT TTCCTCTGCC AGTTTGCTCA GCAGCCCTGC 
TACATAATGT TTTCAGGCCA CCTTAATGAC AATGAGAGGC GAGTTCTACA GACCATCGGC 
ATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

IPO9 ( NM_018085.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_060555.2 Homo sapiens importin 9 (IPO9), mRNA.

Price & Availability↑

CloneID	OHu13394
Clone ID Related Accession (Same CDS sequence)	NM_018085.5 , NM_018085.4
Accession Version	NM_018085.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3126bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	importin-9
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DB232332.1, DA861528.1, AF410465.1, AL645504.10 and AL513217.11. On Aug 18, 2006 this sequence version replaced NM_018085.3. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.200236.1, SRR1803612.277915.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCGG CGGCGGCAGC TGGTGCGGCC TCCGGGCTGC CGGGTCCAGT GGCACAAGGA 
TTAAAGGAAG CGTTAGTGGA TACGCTCACC GGGATCCTAT CCCCAGTACA GGAGGTGCGG 
GCGGCTGCTG AAGAACAGAT TAAGGTGCTG GAGGTGACGG AGGAATTTGG TGTTCACTTG 
GCAGAACTGA CTGTAGATCC CCAGGGGGCA CTGGCAATCC GTCAGCTGGC ATCAGTCATC 
TTGAAACAAT ATGTGGAGAC TCACTGGTGT GCCCAATCAG AGAAATTTAG GCCTCCTGAA 
ACTACAGAAA GGGCAAAAAT TGTTATCCGG GAGCTATTGC CTAATGGGTT GAGAGAATCG 
ATAAGCAAAG TGCGCTCCAG TGTGGCCTAT GCAGTGTCAG CCATTGCCCA CTGGGACTGG 
CCTGAAGCTT GGCCCCAACT CTTCAACCTG CTCATGGAGA TGTTGGTGAG CGGAGACTTA 
AATGCCGTCC ATGGAGCCAT GCGTGTGCTG ACAGAATTCA CTCGTGAAGT AACAGACACA 
CAGATGCCAC TTGTTGCTCC TGTCATTCTC CCAGAGATGT ATAAGATCTT CACCATGGCT 
GAGGTGTATG GTATTCGAAC CCGTTCCCGA GCCGTGGAGA TTTTTACCAC TTGTGCCCAT 
ATGATCTGTA ACATGGAGGA GCTGGAAAAG GGTGCAGCCA AAGTCCTGAT CTTTCCCGTG 
GTACAGCAGT TCACAGAGGC CTTTGTTCAG GCCCTCCAGA TACCAGATGG CCCCACATCT 
GACAGTGGGT TTAAGATGGA GGTCCTAAAG GCAGTGACAG CCCTAGTGAA AAACTTCCCA 
AAGCACATGG TGTCCTCCAT GCAGCAGATT CTGCCTATTG TTTGGAACAC CCTAACCGAG 
AGTGCAGCTT TTTATGTGAG GACAGAAGTA AATTACACAG AAGAAGTAGA AGATCCTGTG 
GATTCTGATG GTGAAGTCCT GGGCTTTGAA AATCTCGTCT TTAGCATTTT TGAATTTGTC 
CATGCTCTAC TAGAAAATAG CAAATTCAAA AGCACTGTTA AGAAAGCCTT GCCTGAATTG 
ATTTATTATA TTATCCTGTA CATGCAAATC ACTGAGGAGC AGATTAAAGT ATGGACAGCC 
AACCCCCAAC AATTTGTAGA AGATGAAGAT GATGATACAT TCTCCTATAC TGTTAGAATA 
GCAGCTCAAG ACTTGTTGCT GGCTGTGGCC ACAGATTTCC AGAATGAAAG TGCAGCAGCC 
CTGGCTGCTG CAGCCACTCG ACATTTACAA GAAGCTGAGC AAACCAAAAA CAGTGGCACT 
GAGCACTGGT GGAAGATCCA TGAGGCATGC ATGCTTGCCC TAGGCTCAGT GAAGGCCATC 
ATCACTGACA GTGTGAAAAA TGGCAGGATT CATTTTGACA TGCATGGGTT CCTGACCAAT 
GTCATCCTTG CAGACCTCAA CCTCTCAGTG TCTCCTTTCC TCTTGGGCCG GGCACTTTGG 
GCTGCCAGTC GGTTCACTGT TGCTATGTCC CCTGAACTGA TCCAGCAGTT CCTACAGGCA 
ACAGTTAGTG GTCTTCACGA GACACAGCCC CCATCAGTTC GAATTTCTGC AGTGAGAGCC 
ATCTGGGGTT ATTGTGACCA ACTGAAAGTC TCAGAGAGTA CCCACGTGCT CCAGCCCTTC 
CTCCCCAGCA TCCTTGATGG CTTAATTCAC CTAGCAGCCC AGTTCAGCTC AGAGGTCCTC 
AACCTGGTGA TGGAGACCCT GTGCATCGTT TGTACAGTAG ACCCCGAATT CACAGCAAGC 
ATGGAAAGCA AAATCTGCCC CTTCACCATC GCCATTTTCC TAAAGTACAG TAATGATCCC 
GTCGTCGCCT CACTGGCTCA GGACATCTTC AAGGAGCTGT CCCAGATTGA AGCCTGTCAG 
GGCCCAATGC AAATGAGGCT GATTCCCACT CTGGTCAGCA TAATGCAGGC CCCAGCAGAC 
AAGATTCCTG CAGGGCTTTG TGCGACAGCC ATTGATATCC TGACAACAGT AGTACGAAAT 
ACAAAGCCTC CCCTTTCCCA GCTTCTCATC TGCCAAGCTT TCCCTGCTGT GGCACAGTGT 
ACCCTTCACA CAGATGACAA TGCCACCATG CAGAATGGCG GAGAGTGCTT GCGGGCCTAT 
GTGTCAGTGA CCCTGGAACA AGTAGCCCAG TGGCATGATG AGCAGGGCCA CAATGGACTG 
TGGTATGTGA TGCAAGTGGT GAGCCAGCTC CTGGACCCCC GCACCTCAGA GTTCACTGCG 
GCCTTTGTGG GCCGCCTTGT TTCCACCCTC ATCTCCAAGG CAGGGCGGGA ACTCGGGGAG 
AATCTAGACC AGATTCTTCG TGCCATCCTC AGTAAGATGC AGCAGGCAGA GACGCTCAGT 
GTCATGCAGT CCCTGATCAT GGTGTTCGCT CATCTGGTGC ACACTCAGCT AGAACCTCTC 
TTGGAGTTCC TGTGTAGCCT CCCAGGACCT ACTGGCAAAC CTGCTCTAGA GTTTGTGATG 
GCTGAGTGGA CAAGCCGACA GCACCTGTTC TATGGACAGT ATGAAGGCAA AGTCAGCTCT 
GTGGCACTCT GTAAGCTGCT CCAGCATGGC ATCAATGCAG ATGACAAACG GCTACAGGAT 
ATCCGTGTGA AGGGAGAGGA GATCTACAGC ATGGATGAGG GCATCCGCAC CCGCTCTAAG 
TCAGCCAAAA ACCCAGAACG CTGGACAAAC ATTCCTTTGC TGGTCAAGAT CCTAAAGCTG 
ATCATCAACG AGCTCTCCAA CGTCATGGAG GCTAATGCCG CTCGCCAGGC CACTCCTGCA 
GAGTGGAGTC AAGATGACTC CAATGATATG TGGGAGGACC AGGAGGAGGA AGAGGAGGAG 
GAGGAGGATG GTTTAGCTGG CCAACTTTTA TCTGACATTC TTGCTACAAG TAAATATGAG 
GAGGATTACT ACGAGGATGA TGAGGAAGAT GACCCTGATG CCCTGAAGGA TCCTCTCTAT 
CAGATTGATC TGCAGGCATA TCTCACAGAT TTCCTCTGCC AGTTTGCTCA GCAGCCCTGC 
TACATAATGT TTTCAGGCCA CCTTAATGAC AATGAGAGGC GAGTTCTACA GACCATCGGC 
ATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060555.2
CDS	51..3176
Translation	MAAAAAAGAASGLPGPVAQGLKEALVDTLTGILSPVQEVRAAAEEQIKVLEVTEEFGVHLAELTVDPQGALAIRQLASVILKQYVETHWCAQSEKFRPPETTERAKIVIRELLPNGLRESISKVRSSVAYAVSAIAHWDWPEAWPQLFNLLMEMLVSGDLNAVHGAMRVLTEFTREVTDTQMPLVAPVILPEMYKIFTMAEVYGIRTRSRAVEIFTTCAHMICNMEELEKGAAKVLIFPVVQQFTEAFVQALQIPDGPTSDSGFKMEVLKAVTALVKNFPKHMVSSMQQILPIVWNTLTESAAFYVRTEVNYTEEVEDPVDSDGEVLGFENLVFSIFEFVHALLENSKFKSTVKKALPELIYYIILYMQITEEQIKVWTANPQQFVEDEDDDTFSYTVRIAAQDLLLAVATDFQNESAAALAAAATRHLQEAEQTKNSGTEHWWKIHEACMLALGSVKAIITDSVKNGRIHFDMHGFLTNVILADLNLSVSPFLLGRALWAASRFTVAMSPELIQQFLQATVSGLHETQPPSVRISAVRAIWGYCDQLKVSESTHVLQPFLPSILDGLIHLAAQFSSEVLNLVMETLCIVCTVDPEFTASMESKICPFTIAIFLKYSNDPVVASLAQDIFKELSQIEACQGPMQMRLIPTLVSIMQAPADKIPAGLCATAIDILTTVVRNTKPPLSQLLICQAFPAVAQCTLHTDDNATMQNGGECLRAYVSVTLEQVAQWHDEQGHNGLWYVMQVVSQLLDPRTSEFTAAFVGRLVSTLISKAGRELGENLDQILRAILSKMQQAETLSVMQSLIMVFAHLVHTQLEPLLEFLCSLPGPTGKPALEFVMAEWTSRQHLFYGQYEGKVSSVALCKLLQHGINADDKRLQDIRVKGEEIYSMDEGIRTRSKSAKNPERWTNIPLLVKILKLIINELSNVMEANAARQATPAEWSQDDSNDMWEDQEEEEEEEEDGLAGQLLSDILATSKYEEDYYEDDEEDDPDALKDPLYQIDLQAYLTDFLCQFAQQPCYIMFSGHLNDNERRVLQTIGI

Target ORF information:

RefSeq Version	NM_018085.4
Organism	Homo sapiens(human)
Definition	Homo sapiens importin 9 (IPO9), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018085.4

ORF Insert Sequence:

ATGGCGGCGG CGGCGGCAGC TGGTGCGGCC TCCGGGCTGC CGGGTCCAGT GGCACAAGGA 
TTAAAGGAAG CGTTAGTGGA TACGCTCACC GGGATCCTAT CCCCAGTACA GGAGGTGCGG 
GCGGCTGCTG AAGAACAGAT TAAGGTGCTG GAGGTGACGG AGGAATTTGG TGTTCACTTG 
GCAGAACTGA CTGTAGATCC CCAGGGGGCA CTGGCAATCC GTCAGCTGGC ATCAGTCATC 
TTGAAACAAT ATGTGGAGAC TCACTGGTGT GCCCAATCAG AGAAATTTAG GCCTCCTGAA 
ACTACAGAAA GGGCAAAAAT TGTTATCCGG GAGCTATTGC CTAATGGGTT GAGAGAATCG 
ATAAGCAAAG TGCGCTCCAG TGTGGCCTAT GCAGTGTCAG CCATTGCCCA CTGGGACTGG 
CCTGAAGCTT GGCCCCAACT CTTCAACCTG CTCATGGAGA TGTTGGTGAG CGGAGACTTA 
AATGCCGTCC ATGGAGCCAT GCGTGTGCTG ACAGAATTCA CTCGTGAAGT AACAGACACA 
CAGATGCCAC TTGTTGCTCC TGTCATTCTC CCAGAGATGT ATAAGATCTT CACCATGGCT 
GAGGTGTATG GTATTCGAAC CCGTTCCCGA GCCGTGGAGA TTTTTACCAC TTGTGCCCAT 
ATGATCTGTA ACATGGAGGA GCTGGAAAAG GGTGCAGCCA AAGTCCTGAT CTTTCCCGTG 
GTACAGCAGT TCACAGAGGC CTTTGTTCAG GCCCTCCAGA TACCAGATGG CCCCACATCT 
GACAGTGGGT TTAAGATGGA GGTCCTAAAG GCAGTGACAG CCCTAGTGAA AAACTTCCCA 
AAGCACATGG TGTCCTCCAT GCAGCAGATT CTGCCTATTG TTTGGAACAC CCTAACCGAG 
AGTGCAGCTT TTTATGTGAG GACAGAAGTA AATTACACAG AAGAAGTAGA AGATCCTGTG 
GATTCTGATG GTGAAGTCCT GGGCTTTGAA AATCTCGTCT TTAGCATTTT TGAATTTGTC 
CATGCTCTAC TAGAAAATAG CAAATTCAAA AGCACTGTTA AGAAAGCCTT GCCTGAATTG 
ATTTATTATA TTATCCTGTA CATGCAAATC ACTGAGGAGC AGATTAAAGT ATGGACAGCC 
AACCCCCAAC AATTTGTAGA AGATGAAGAT GATGATACAT TCTCCTATAC TGTTAGAATA 
GCAGCTCAAG ACTTGTTGCT GGCTGTGGCC ACAGATTTCC AGAATGAAAG TGCAGCAGCC 
CTGGCTGCTG CAGCCACTCG ACATTTACAA GAAGCTGAGC AAACCAAAAA CAGTGGCACT 
GAGCACTGGT GGAAGATCCA TGAGGCATGC ATGCTTGCCC TAGGCTCAGT GAAGGCCATC 
ATCACTGACA GTGTGAAAAA TGGCAGGATT CATTTTGACA TGCATGGGTT CCTGACCAAT 
GTCATCCTTG CAGACCTCAA CCTCTCAGTG TCTCCTTTCC TCTTGGGCCG GGCACTTTGG 
GCTGCCAGTC GGTTCACTGT TGCTATGTCC CCTGAACTGA TCCAGCAGTT CCTACAGGCA 
ACAGTTAGTG GTCTTCACGA GACACAGCCC CCATCAGTTC GAATTTCTGC AGTGAGAGCC 
ATCTGGGGTT ATTGTGACCA ACTGAAAGTC TCAGAGAGTA CCCACGTGCT CCAGCCCTTC 
CTCCCCAGCA TCCTTGATGG CTTAATTCAC CTAGCAGCCC AGTTCAGCTC AGAGGTCCTC 
AACCTGGTGA TGGAGACCCT GTGCATCGTT TGTACAGTAG ACCCCGAATT CACAGCAAGC 
ATGGAAAGCA AAATCTGCCC CTTCACCATC GCCATTTTCC TAAAGTACAG TAATGATCCC 
GTCGTCGCCT CACTGGCTCA GGACATCTTC AAGGAGCTGT CCCAGATTGA AGCCTGTCAG 
GGCCCAATGC AAATGAGGCT GATTCCCACT CTGGTCAGCA TAATGCAGGC CCCAGCAGAC 
AAGATTCCTG CAGGGCTTTG TGCGACAGCC ATTGATATCC TGACAACAGT AGTACGAAAT 
ACAAAGCCTC CCCTTTCCCA GCTTCTCATC TGCCAAGCTT TCCCTGCTGT GGCACAGTGT 
ACCCTTCACA CAGATGACAA TGCCACCATG CAGAATGGCG GAGAGTGCTT GCGGGCCTAT 
GTGTCAGTGA CCCTGGAACA AGTAGCCCAG TGGCATGATG AGCAGGGCCA CAATGGACTG 
TGGTATGTGA TGCAAGTGGT GAGCCAGCTC CTGGACCCCC GCACCTCAGA GTTCACTGCG 
GCCTTTGTGG GCCGCCTTGT TTCCACCCTC ATCTCCAAGG CAGGGCGGGA ACTCGGGGAG 
AATCTAGACC AGATTCTTCG TGCCATCCTC AGTAAGATGC AGCAGGCAGA GACGCTCAGT 
GTCATGCAGT CCCTGATCAT GGTGTTCGCT CATCTGGTGC ACACTCAGCT AGAACCTCTC 
TTGGAGTTCC TGTGTAGCCT CCCAGGACCT ACTGGCAAAC CTGCTCTAGA GTTTGTGATG 
GCTGAGTGGA CAAGCCGACA GCACCTGTTC TATGGACAGT ATGAAGGCAA AGTCAGCTCT 
GTGGCACTCT GTAAGCTGCT CCAGCATGGC ATCAATGCAG ATGACAAACG GCTACAGGAT 
ATCCGTGTGA AGGGAGAGGA GATCTACAGC ATGGATGAGG GCATCCGCAC CCGCTCTAAG 
TCAGCCAAAA ACCCAGAACG CTGGACAAAC ATTCCTTTGC TGGTCAAGAT CCTAAAGCTG 
ATCATCAACG AGCTCTCCAA CGTCATGGAG GCTAATGCCG CTCGCCAGGC CACTCCTGCA 
GAGTGGAGTC AAGATGACTC CAATGATATG TGGGAGGACC AGGAGGAGGA AGAGGAGGAG 
GAGGAGGATG GTTTAGCTGG CCAACTTTTA TCTGACATTC TTGCTACAAG TAAATATGAG 
GAGGATTACT ACGAGGATGA TGAGGAAGAT GACCCTGATG CCCTGAAGGA TCCTCTCTAT 
CAGATTGATC TGCAGGCATA TCTCACAGAT TTCCTCTGCC AGTTTGCTCA GCAGCCCTGC 
TACATAATGT TTTCAGGCCA CCTTAATGAC AATGAGAGGC GAGTTCTACA GACCATCGGC 
ATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Downregulation of importin-9 protects MCF-7 cells against apoptosis induced by the combination of garlic-derived alliin and paclitaxel.
Oncology reports35(5)3084-93(2016 May)
Izdebska M,Grzanka D,Gagat M,Ha?as-Wi?niewska M,Grzanka A

Novel role for molecular transporter importin 9 in posttranscriptional regulation of IFN-? expression.
Journal of immunology (Baltimore, Md. : 1950)191(4)1907-15(2013 Aug)
Matsumiya T,Xing F,Ebina M,Hayakari R,Imaizumi T,Yoshida H,Kikuchi H,Topham MK,Satoh K,Stafforini DM

Defining the membrane proteome of NK cells.
Journal of mass spectrometry : JMS45(1)1-25(2010 Jan)
Ghosh D,Lippert D,Krokhin O,Cortens JP,Wilkins JA

Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach.
Cell cycle (Georgetown, Tex.)6(2)205-17(2007 Jan)
Koch HB,Zhang R,Verdoodt B,Bailey A,Zhang CD,Yates JR 3rd,Menssen A,Hermeking H

Inhibition of nuclear import by the proapoptotic protein CC3.
Molecular and cellular biology24(16)7091-101(2004 Aug)
King FW,Shtivelman E

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IPO9 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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