PKIA cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PKIA
Entrez Gene ID	5569
Full Name	cAMP-dependent protein kinase inhibitor alpha
Synonyms	PRKACN1
General protein information	Preferred Names cAMP-dependent protein kinase inhibitor alpha Names cAMP-dependent protein kinase inhibitor alpha PKI-alpha cAMP-dependent protein kinase inhibitor, muscle/brain isoform protein kinase (cAMP-dependent, catalytic) inhibitor alpha
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 8 Map Location: 8q21.13
Summary	The protein encoded by this gene is a member of the cAMP-dependent protein kinase (PKA) inhibitor family. This protein was demonstrated to interact with and inhibit the activities of both C alpha and C beta catalytic subunits of the PKA. Alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008].
Disorder MIM:	606059

mRNA and Protein(s)

mRNA	Protein	Name
XM_017013622.1	XP_016869111.1	cAMP-dependent protein kinase inhibitor alpha isoform X1
XM_017013622.2	XP_016869111.1	cAMP-dependent protein kinase inhibitor alpha isoform X1
NM_181839.2	NP_862822.1	cAMP-dependent protein kinase inhibitor alpha
NM_006823.3	NP_006814.1	cAMP-dependent protein kinase inhibitor alpha
XM_017013621.1	XP_016869110.1	cAMP-dependent protein kinase inhibitor alpha isoform X1
NM_181839.3	NP_862822.1	cAMP-dependent protein kinase inhibitor alpha
NM_006823.4	NP_006814.1	cAMP-dependent protein kinase inhibitor alpha
XM_017013620.1	XP_016869109.1	cAMP-dependent protein kinase inhibitor alpha isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	PKIA	NP_862822.1
Canis lupus familiaris (dog)	PKIA	XP_853383.2
Xenopus tropicalis (tropical clawed frog)	pkia	NP_001025580.1
Bos taurus (cattle)	PKIA	NP_001032709.1
Rattus norvegicus (Norway rat)	Pkia	NP_446224.1
Pan troglodytes (chimpanzee)	PKIA	XP_003311822.1
	PKIA	XP_002805436.1
Gallus gallus (chicken)	PKIA	NP_990705.1
Mus musculus (house mouse)	Pkia	NP_032888.1

Gene Ontology
Bibliography

Related articles in PubMed

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture.
Estrada K, Styrkarsdottir U, Evangelou E, Hsu YH, Duncan EL, Ntzani EE, Oei L, Albagha OM, Amin N, Kemp JP, Koller DL, Li G, Liu CT, Minster RL, Moayyeri A, Vandenput L, Willner D, Xiao SM, Yerges-Armstrong LM, Zheng HF, Alonso N, Eriksson J, Kammerer CM, Kaptoge SK, Leo PJ, Thorleifsson G, Wilson SG, Wilson JF, Aalto V, Alen M, Aragaki AK, Aspelund T, Center JR, Dailiana Z, Duggan DJ, Garcia M, Garcia-Giralt N, Giroux S, Hallmans G, Hocking LJ, Husted LB, Jameson KA, Khusainova R, Kim GS, Kooperberg C, Koromila T, Kruk M, Laaksonen M, Lacroix AZ, Lee SH, Leung PC, Lewis JR, Masi L, Mencej-Bedrac S, Nguyen TV, Nogues X, Patel MS, Prezelj J, Rose LM, Scollen S, Siggeirsdottir K, Smith AV, Svensson O, Trompet S, Trummer O, van Schoor NM, Woo J, Zhu K, Balcells S, Brandi ML, Buckley BM, Cheng S, Christiansen C, Cooper C, Dedoussis G, Ford I, Frost M, Goltzman D, Gonz?lez-Mac?as J, K?h?nen M, Karlsson M, Khusnutdinova E, Koh JM, Kollia P, Langdahl BL, Leslie WD, Lips P, Ljunggren ?, Lorenc RS, Marc J, Mellstr?m D, Obermayer-Pietsch B, Olmos JM, Pettersson-Kymmer U, Reid DM, Riancho JA, Ridker PM, Rousseau F, Slagboom PE, Tang NL, Urreizti R, Van Hul W, Viikari J, Zarrabeitia MT, Aulchenko YS, Castano-Betancourt M, Grundberg E, Herrera L, Ingvarsson T, Johannsdottir H, Kwan T, Li R, Luben R, Medina-G?mez C, Palsson ST, Reppe S, Rotter JI, Sigurdsson G, van Meurs JB, Verlaan D, Williams FM, Wood AR, Zhou Y, Gautvik KM, Pastinen T, Raychaudhuri S, Cauley JA, Chasman DI, Clark GR, Cummings SR, Danoy P, Dennison EM, Eastell R, Eisman JA, Gudnason V, Hofman A, Jackson RD, Jones G, Jukema JW, Khaw KT, Lehtim?ki T, Liu Y, Lorentzon M, McCloskey E, Mitchell BD, Nandakumar K, Nicholson GC, Oostra BA, Peacock M, Pols HA, Prince RL, Raitakari O, Reid IR, Robbins J, Sambrook PN, Sham PC, Shuldiner AR, Tylavsky FA, van Duijn CM, Wareham NJ, Cupples LA, Econs MJ, Evans DM, Harris TB, Kung AW, Psaty BM, Reeve J, Spector TD, Streeten EA, Zillikens MC, Thorsteinsdottir U, Ohlsson C, Karasik D, Richards JB, Brown MA, Stefansson K, Uitterlinden AG, Ralston SH, Ioannidis JP, Kiel DP, Rivadeneira F
Nature genetics44(5)491-501(2012 Apr)

A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.
Tao S, Wang Z, Feng J, Hsu FC, Jin G, Kim ST, Zhang Z, Gronberg H, Zheng LS, Isaacs WB, Xu J, Sun J
Carcinogenesis33(3)598-603(2012 Mar)

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.
, , Sawcer S, Hellenthal G, Pirinen M, Spencer CC, Patsopoulos NA, Moutsianas L, Dilthey A, Su Z, Freeman C, Hunt SE, Edkins S, Gray E, Booth DR, Potter SC, Goris A, Band G, Oturai AB, Strange A, Saarela J, Bellenguez C, Fontaine B, Gillman M, Hemmer B, Gwilliam R, Zipp F, Jayakumar A, Martin R, Leslie S, Hawkins S, Giannoulatou E, D'alfonso S, Blackburn H, Martinelli Boneschi F, Liddle J, Harbo HF, Perez ML, Spurkland A, Waller MJ, Mycko MP, Ricketts M, Comabella M, Hammond N, Kockum I, McCann OT, Ban M, Whittaker P, Kemppinen A, Weston P, Hawkins C, Widaa S, Zajicek J, Dronov S, Robertson N, Bumpstead SJ, Barcellos LF, Ravindrarajah R, Abraham R, Alfredsson L, Ardlie K, Aubin C, Baker A, Baker K, Baranzini SE, Bergamaschi L, Bergamaschi R, Bernstein A, Berthele A, Boggild M, Bradfield JP, Brassat D, Broadley SA, Buck D, Butzkueven H, Capra R, Carroll WM, Cavalla P, Celius EG, Cepok S, Chiavacci R, Clerget-Darpoux F, Clysters K, Comi G, Cossburn M, Cournu-Rebeix I, Cox MB, Cozen W, Cree BA, Cross AH, Cusi D, Daly MJ, Davis E, de Bakker PI, Debouverie M, D'hooghe MB, Dixon K, Dobosi R, Dubois B, Ellinghaus D, Elovaara I, Esposito F, Fontenille C, Foote S, Franke A, Galimberti D, Ghezzi A, Glessner J, Gomez R, Gout O, Graham C, Grant SF, Guerini FR, Hakonarson H, Hall P, Hamsten A, Hartung HP, Heard RN, Heath S, Hobart J, Hoshi M, Infante-Duarte C, Ingram G, Ingram W, Islam T, Jagodic M, Kabesch M, Kermode AG, Kilpatrick TJ, Kim C, Klopp N, Koivisto K, Larsson M, Lathrop M, Lechner-Scott JS, Leone MA, Lepp? V, Liljedahl U, Bomfim IL, Lincoln RR, Link J, Liu J, Lorentzen AR, Lupoli S, Macciardi F, Mack T, Marriott M, Martinelli V, Mason D, McCauley JL, Mentch F, Mero IL, Mihalova T, Montalban X, Mottershead J, Myhr KM, Naldi P, Ollier W, Page A, Palotie A, Pelletier J, Piccio L, Pickersgill T, Piehl F, Pobywajlo S, Quach HL, Ramsay PP, Reunanen M, Reynolds R, Rioux JD, Rodegher M, Roesner S, Rubio JP, R?ckert IM, Salvetti M, Salvi E, Santaniello A, Schaefer CA, Schreiber S, Schulze C, Scott RJ, Sellebjerg F, Selmaj KW, Sexton D, Shen L, Simms-Acuna B, Skidmore S, Sleiman PM, Smestad C, S?rensen PS, S?ndergaard HB, Stankovich J, Strange RC, Sulonen AM, Sundqvist E, Syv?nen AC, Taddeo F, Taylor B, Blackwell JM, Tienari P, Bramon E, Tourbah A, Brown MA, Tronczynska E, Casas JP, Tubridy N, Corvin A, Vickery J, Jankowski J, Villoslada P, Markus HS, Wang K, Mathew CG, Wason J, Palmer CN, Wichmann HE, Plomin R, Willoughby E, Rautanen A, Winkelmann J, Wittig M, Trembath RC, Yaouanq J, Viswanathan AC, Zhang H, Wood NW, Zuvich R, Deloukas P, Langford C, Duncanson A, Oksenberg JR, Pericak-Vance MA, Haines JL, Olsson T, Hillert J, Ivinson AJ, De Jager PL, Peltonen L, Stewart GJ, Hafler DA, Hauser SL, McVean G, Donnelly P, Compston A
Nature476(7359)214-9(2011 Aug)

The testis-specific C?2 subunit of PKA is kinetically indistinguishable from the common C?1 subunit of PKA.
Vetter MM, Zenn HM, M?ndez E, van den Boom H, Herberg FW, Sk?lhegg BS
BMC biochemistry1240(2011 Aug)

NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1.
G?ttler T, Madl T, Neumann P, Deichsel D, Corsini L, Monecke T, Ficner R, Sattler M, G?rlich D
Nature structural & molecular biology17(11)1367-76(2010 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Observational study and genome-wide association study of gene-disease association. (HuGE Navigator)
Title: A genome-wide association study of bipolar disorder in Norwegian individuals, followed by replication in Icelandic sample.

The following PKIA gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PKIA cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu08088	NM_181839.3 Latest version!	Homo sapiens cAMP-dependent protein kinase inhibitor alpha (PKIA), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu08088	NM_006823.4 Latest version!	Homo sapiens cAMP-dependent protein kinase inhibitor alpha (PKIA), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu08088	XM_017013620.1 Latest version!	Homo sapiens cAMP-dependent protein kinase inhibitor alpha (PKIA), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu08088	XM_017013621.1 Latest version!	Homo sapiens cAMP-dependent protein kinase inhibitor alpha (PKIA), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu08088	XM_017013622.2 Latest version!	Homo sapiens cAMP-dependent protein kinase inhibitor alpha (PKIA), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu08088	XM_017013622.1	Homo sapiens protein kinase (cAMP-dependent, catalytic) inhibitor alpha (PKIA), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu08088	NM_181839.2	Homo sapiens cAMP-dependent protein kinase inhibitor alpha (PKIA), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu08088	NM_006823.3	Homo sapiens cAMP-dependent protein kinase inhibitor alpha (PKIA), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PKIA ( NM_181839.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_862822.1 Homo sapiens cAMP-dependent protein kinase inhibitor alpha (PKIA), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu08088
Clone ID Related Accession (Same CDS sequence)	XM_017013622.1 , XM_017013622.2 , NM_181839.2 , NM_006823.3 , XM_017013621.1 , NM_181839.3 , NM_006823.4 , XM_017013620.1
Accession Version	NM_181839.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 231bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-24
Organism	Homo sapiens(human)
Product	cAMP-dependent protein kinase inhibitor alpha
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC068700.5 and DB480496.1. On Mar 10, 2011 this sequence version replaced NM_181839.1. Transcript Variant: This variant (2) lacks an exon in the 5' UTR, as compared to variant 1. Both variants encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.196496.1, SRR1803614.149692.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACTGATG TGGAAACTAC ATATGCAGAT TTTATTGCTT CAGGAAGAAC AGGTAGAAGA 
AATGCAATAC ATGATATCCT GGTTTCCTCT GCAAGTGGCA ACAGCAATGA ATTAGCCTTG 
AAATTAGCAG GTCTTGATAT CAACAAGACA GAAGGTGAAG AAGATGCACA ACGAAGTTCT 
ACAGAACAAA GTGGGGAAGC CCAGGGAGAA GCAGCAAAAT CTGAAAGCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_862822.1
CDS	396..626
Translation	MTDVETTYADFIASGRTGRRNAIHDILVSSASGNSNELALKLAGLDINKTEGEEDAQRSSTEQSGEAQGEAAKSES

Target ORF information:

RefSeq Version	NM_181839.2
Organism	Homo sapiens(human)
Definition	Homo sapiens cAMP-dependent protein kinase inhibitor alpha (PKIA), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_181839.2

ORF Insert Sequence:

ATGACTGATG TGGAAACTAC ATATGCAGAT TTTATTGCTT CAGGAAGAAC AGGTAGAAGA 
AATGCAATAC ATGATATCCT GGTTTCCTCT GCAAGTGGCA ACAGCAATGA ATTAGCCTTG 
AAATTAGCAG GTCTTGATAT CAACAAGACA GAAGGTGAAG AAGATGCACA ACGAAGTTCT 
ACAGAACAAA GTGGGGAAGC CCAGGGAGAA GCAGCAAAAT CTGAAAGCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PKIA ( NM_006823.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_006814.1 Homo sapiens cAMP-dependent protein kinase inhibitor alpha (PKIA), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu08088
Clone ID Related Accession (Same CDS sequence)	XM_017013622.1 , XM_017013622.2 , NM_181839.2 , NM_006823.3 , XM_017013621.1 , NM_181839.3 , NM_006823.4 , XM_017013620.1
Accession Version	NM_006823.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 231bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	cAMP-dependent protein kinase inhibitor alpha
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC068700.5, BI597731.1, BC022265.2, DR763580.1, BX419914.2 and CR744438.1. On Mar 10, 2011 this sequence version replaced NM_006823.2. Transcript Variant: This variant (1) differs the in the 5' UTR, as compared to variant 2. Both variants encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.212392.1, SRR1803616.154936.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACTGATG TGGAAACTAC ATATGCAGAT TTTATTGCTT CAGGAAGAAC AGGTAGAAGA 
AATGCAATAC ATGATATCCT GGTTTCCTCT GCAAGTGGCA ACAGCAATGA ATTAGCCTTG 
AAATTAGCAG GTCTTGATAT CAACAAGACA GAAGGTGAAG AAGATGCACA ACGAAGTTCT 
ACAGAACAAA GTGGGGAAGC CCAGGGAGAA GCAGCAAAAT CTGAAAGCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006814.1
CDS	525..755
Translation	MTDVETTYADFIASGRTGRRNAIHDILVSSASGNSNELALKLAGLDINKTEGEEDAQRSSTEQSGEAQGEAAKSES

Target ORF information:

RefSeq Version	NM_006823.3
Organism	Homo sapiens(human)
Definition	Homo sapiens cAMP-dependent protein kinase inhibitor alpha (PKIA), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006823.3

ORF Insert Sequence:

ATGACTGATG TGGAAACTAC ATATGCAGAT TTTATTGCTT CAGGAAGAAC AGGTAGAAGA 
AATGCAATAC ATGATATCCT GGTTTCCTCT GCAAGTGGCA ACAGCAATGA ATTAGCCTTG 
AAATTAGCAG GTCTTGATAT CAACAAGACA GAAGGTGAAG AAGATGCACA ACGAAGTTCT 
ACAGAACAAA GTGGGGAAGC CCAGGGAGAA GCAGCAAAAT CTGAAAGCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PKIA ( NM_181839.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_862822.1 Homo sapiens cAMP-dependent protein kinase inhibitor alpha (PKIA), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu08088
Clone ID Related Accession (Same CDS sequence)	XM_017013622.1 , XM_017013622.2 , NM_181839.2 , NM_006823.3 , XM_017013621.1 , NM_181839.3 , NM_006823.4 , XM_017013620.1
Accession Version	NM_181839.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 231bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Homo sapiens(human)
Product	cAMP-dependent protein kinase inhibitor alpha
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB480496.1 and AC068700.5. On May 31, 2019 this sequence version replaced NM_181839.2. Transcript Variant: This variant (2) lacks an exon in the 5' UTR, as compared to variant 1. Both variants encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.110740.1, SRR1660803.16943.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACTGATG TGGAAACTAC ATATGCAGAT TTTATTGCTT CAGGAAGAAC AGGTAGAAGA 
AATGCAATAC ATGATATCCT GGTTTCCTCT GCAAGTGGCA ACAGCAATGA ATTAGCCTTG 
AAATTAGCAG GTCTTGATAT CAACAAGACA GAAGGTGAAG AAGATGCACA ACGAAGTTCT 
ACAGAACAAA GTGGGGAAGC CCAGGGAGAA GCAGCAAAAT CTGAAAGCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_862822.1
CDS	157..387
Translation	MTDVETTYADFIASGRTGRRNAIHDILVSSASGNSNELALKLAGLDINKTEGEEDAQRSSTEQSGEAQGEAAKSES

Target ORF information:

RefSeq Version	NM_181839.3
Organism	Homo sapiens(human)
Definition	Homo sapiens cAMP-dependent protein kinase inhibitor alpha (PKIA), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_181839.3

ORF Insert Sequence:

ATGACTGATG TGGAAACTAC ATATGCAGAT TTTATTGCTT CAGGAAGAAC AGGTAGAAGA 
AATGCAATAC ATGATATCCT GGTTTCCTCT GCAAGTGGCA ACAGCAATGA ATTAGCCTTG 
AAATTAGCAG GTCTTGATAT CAACAAGACA GAAGGTGAAG AAGATGCACA ACGAAGTTCT 
ACAGAACAAA GTGGGGAAGC CCAGGGAGAA GCAGCAAAAT CTGAAAGCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PKIA ( NM_006823.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_006814.1 Homo sapiens cAMP-dependent protein kinase inhibitor alpha (PKIA), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu08088
Clone ID Related Accession (Same CDS sequence)	XM_017013622.1 , XM_017013622.2 , NM_181839.2 , NM_006823.3 , XM_017013621.1 , NM_181839.3 , NM_006823.4 , XM_017013620.1
Accession Version	NM_006823.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 231bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	cAMP-dependent protein kinase inhibitor alpha
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI597731.1, BC022265.2, DR763580.1, BX419914.2 and CR744438.1. On Nov 23, 2018 this sequence version replaced NM_006823.3. Transcript Variant: This variant (1) differs the in the 5' UTR, as compared to variant 2. Both variants encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.274429.1, SRR1803616.154936.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000396418.7/ ENSP00000379696.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGACTGATG TGGAAACTAC ATATGCAGAT TTTATTGCTT CAGGAAGAAC AGGTAGAAGA 
AATGCAATAC ATGATATCCT GGTTTCCTCT GCAAGTGGCA ACAGCAATGA ATTAGCCTTG 
AAATTAGCAG GTCTTGATAT CAACAAGACA GAAGGTGAAG AAGATGCACA ACGAAGTTCT 
ACAGAACAAA GTGGGGAAGC CCAGGGAGAA GCAGCAAAAT CTGAAAGCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006814.1
CDS	286..516
Translation	MTDVETTYADFIASGRTGRRNAIHDILVSSASGNSNELALKLAGLDINKTEGEEDAQRSSTEQSGEAQGEAAKSES

Target ORF information:

RefSeq Version	NM_006823.4
Organism	Homo sapiens(human)
Definition	Homo sapiens cAMP-dependent protein kinase inhibitor alpha (PKIA), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006823.4

ORF Insert Sequence:

ATGACTGATG TGGAAACTAC ATATGCAGAT TTTATTGCTT CAGGAAGAAC AGGTAGAAGA 
AATGCAATAC ATGATATCCT GGTTTCCTCT GCAAGTGGCA ACAGCAATGA ATTAGCCTTG 
AAATTAGCAG GTCTTGATAT CAACAAGACA GAAGGTGAAG AAGATGCACA ACGAAGTTCT 
ACAGAACAAA GTGGGGAAGC CCAGGGAGAA GCAGCAAAAT CTGAAAGCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PKIA ( XM_017013622.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016869111.1 Homo sapiens protein kinase (cAMP-dependent, catalytic) inhibitor alpha (PKIA), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu08088
Clone ID Related Accession (Same CDS sequence)	XM_017013622.1 , XM_017013622.2 , NM_181839.2 , NM_006823.3 , XM_017013621.1 , NM_181839.3 , NM_006823.4 , XM_017013620.1
Accession Version	XM_017013622.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 231bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	cAMP-dependent protein kinase inhibitor alpha isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACTGATG TGGAAACTAC ATATGCAGAT TTTATTGCTT CAGGAAGAAC AGGTAGAAGA 
AATGCAATAC ATGATATCCT GGTTTCCTCT GCAAGTGGCA ACAGCAATGA ATTAGCCTTG 
AAATTAGCAG GTCTTGATAT CAACAAGACA GAAGGTGAAG AAGATGCACA ACGAAGTTCT 
ACAGAACAAA GTGGGGAAGC CCAGGGAGAA GCAGCAAAAT CTGAAAGCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016869111.1
CDS	131..361
Translation	MTDVETTYADFIASGRTGRRNAIHDILVSSASGNSNELALKLAGLDINKTEGEEDAQRSSTEQSGEAQGEAAKSES

Target ORF information:

RefSeq Version	XM_017013622.1
Organism	Homo sapiens(human)
Definition	Homo sapiens protein kinase (cAMP-dependent, catalytic) inhibitor alpha (PKIA), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017013622.1

ORF Insert Sequence:

ATGACTGATG TGGAAACTAC ATATGCAGAT TTTATTGCTT CAGGAAGAAC AGGTAGAAGA 
AATGCAATAC ATGATATCCT GGTTTCCTCT GCAAGTGGCA ACAGCAATGA ATTAGCCTTG 
AAATTAGCAG GTCTTGATAT CAACAAGACA GAAGGTGAAG AAGATGCACA ACGAAGTTCT 
ACAGAACAAA GTGGGGAAGC CCAGGGAGAA GCAGCAAAAT CTGAAAGCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PKIA ( XM_017013622.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_016869111.1 Homo sapiens cAMP-dependent protein kinase inhibitor alpha (PKIA), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu08088
Clone ID Related Accession (Same CDS sequence)	XM_017013622.1 , XM_017013622.2 , NM_181839.2 , NM_006823.3 , XM_017013621.1 , NM_181839.3 , NM_006823.4 , XM_017013620.1
Accession Version	XM_017013622.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 231bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	cAMP-dependent protein kinase inhibitor alpha isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017013622.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACTGATG TGGAAACTAC ATATGCAGAT TTTATTGCTT CAGGAAGAAC AGGTAGAAGA 
AATGCAATAC ATGATATCCT GGTTTCCTCT GCAAGTGGCA ACAGCAATGA ATTAGCCTTG 
AAATTAGCAG GTCTTGATAT CAACAAGACA GAAGGTGAAG AAGATGCACA ACGAAGTTCT 
ACAGAACAAA GTGGGGAAGC CCAGGGAGAA GCAGCAAAAT CTGAAAGCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016869111.1
CDS	81..311
Translation	MTDVETTYADFIASGRTGRRNAIHDILVSSASGNSNELALKLAGLDINKTEGEEDAQRSSTEQSGEAQGEAAKSES

Target ORF information:

RefSeq Version	XM_017013622.2
Organism	Homo sapiens(human)
Definition	Homo sapiens cAMP-dependent protein kinase inhibitor alpha (PKIA), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017013622.2

ORF Insert Sequence:

ATGACTGATG TGGAAACTAC ATATGCAGAT TTTATTGCTT CAGGAAGAAC AGGTAGAAGA 
AATGCAATAC ATGATATCCT GGTTTCCTCT GCAAGTGGCA ACAGCAATGA ATTAGCCTTG 
AAATTAGCAG GTCTTGATAT CAACAAGACA GAAGGTGAAG AAGATGCACA ACGAAGTTCT 
ACAGAACAAA GTGGGGAAGC CCAGGGAGAA GCAGCAAAAT CTGAAAGCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PKIA ( XM_017013621.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016869110.1 Homo sapiens cAMP-dependent protein kinase inhibitor alpha (PKIA), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu08088
Clone ID Related Accession (Same CDS sequence)	XM_017013622.1 , XM_017013622.2 , NM_181839.2 , NM_006823.3 , XM_017013621.1 , NM_181839.3 , NM_006823.4 , XM_017013620.1
Accession Version	XM_017013621.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 231bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	cAMP-dependent protein kinase inhibitor alpha isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACTGATG TGGAAACTAC ATATGCAGAT TTTATTGCTT CAGGAAGAAC AGGTAGAAGA 
AATGCAATAC ATGATATCCT GGTTTCCTCT GCAAGTGGCA ACAGCAATGA ATTAGCCTTG 
AAATTAGCAG GTCTTGATAT CAACAAGACA GAAGGTGAAG AAGATGCACA ACGAAGTTCT 
ACAGAACAAA GTGGGGAAGC CCAGGGAGAA GCAGCAAAAT CTGAAAGCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016869110.1
CDS	366..596
Translation	MTDVETTYADFIASGRTGRRNAIHDILVSSASGNSNELALKLAGLDINKTEGEEDAQRSSTEQSGEAQGEAAKSES

Target ORF information:

RefSeq Version	XM_017013621.1
Organism	Homo sapiens(human)
Definition	Homo sapiens cAMP-dependent protein kinase inhibitor alpha (PKIA), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017013621.1

ORF Insert Sequence:

ATGACTGATG TGGAAACTAC ATATGCAGAT TTTATTGCTT CAGGAAGAAC AGGTAGAAGA 
AATGCAATAC ATGATATCCT GGTTTCCTCT GCAAGTGGCA ACAGCAATGA ATTAGCCTTG 
AAATTAGCAG GTCTTGATAT CAACAAGACA GAAGGTGAAG AAGATGCACA ACGAAGTTCT 
ACAGAACAAA GTGGGGAAGC CCAGGGAGAA GCAGCAAAAT CTGAAAGCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PKIA ( XM_017013620.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016869109.1 Homo sapiens cAMP-dependent protein kinase inhibitor alpha (PKIA), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu08088
Clone ID Related Accession (Same CDS sequence)	XM_017013622.1 , XM_017013622.2 , NM_181839.2 , NM_006823.3 , XM_017013621.1 , NM_181839.3 , NM_006823.4 , XM_017013620.1
Accession Version	XM_017013620.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 231bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	cAMP-dependent protein kinase inhibitor alpha isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACTGATG TGGAAACTAC ATATGCAGAT TTTATTGCTT CAGGAAGAAC AGGTAGAAGA 
AATGCAATAC ATGATATCCT GGTTTCCTCT GCAAGTGGCA ACAGCAATGA ATTAGCCTTG 
AAATTAGCAG GTCTTGATAT CAACAAGACA GAAGGTGAAG AAGATGCACA ACGAAGTTCT 
ACAGAACAAA GTGGGGAAGC CCAGGGAGAA GCAGCAAAAT CTGAAAGCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016869109.1
CDS	400..630
Translation	MTDVETTYADFIASGRTGRRNAIHDILVSSASGNSNELALKLAGLDINKTEGEEDAQRSSTEQSGEAQGEAAKSES

Target ORF information:

RefSeq Version	XM_017013620.1
Organism	Homo sapiens(human)
Definition	Homo sapiens cAMP-dependent protein kinase inhibitor alpha (PKIA), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017013620.1

ORF Insert Sequence:

ATGACTGATG TGGAAACTAC ATATGCAGAT TTTATTGCTT CAGGAAGAAC AGGTAGAAGA 
AATGCAATAC ATGATATCCT GGTTTCCTCT GCAAGTGGCA ACAGCAATGA ATTAGCCTTG 
AAATTAGCAG GTCTTGATAT CAACAAGACA GAAGGTGAAG AAGATGCACA ACGAAGTTCT 
ACAGAACAAA GTGGGGAAGC CCAGGGAGAA GCAGCAAAAT CTGAAAGCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture.
Nature genetics44(5)491-501(2012 Apr)
Estrada K,Styrkarsdottir U,Evangelou E,Hsu YH,Duncan EL,Ntzani EE,Oei L,Albagha OM,Amin N,Kemp JP,Koller DL,Li G,Liu CT,Minster RL,Moayyeri A,Vandenput L,Willner D,Xiao SM,Yerges-Armstrong LM,Zheng HF,Alonso N,Eriksson J,Kammerer CM,Kaptoge SK,Leo PJ,Thorleifsson G,Wilson SG,Wilson JF,Aalto V,Alen M,Aragaki AK,Aspelund T,Center JR,Dailiana Z,Duggan DJ,Garcia M,Garcia-Giralt N,Giroux S,Hallmans G,Hocking LJ,Husted LB,Jameson KA,Khusainova R,Kim GS,Kooperberg C,Koromila T,Kruk M,Laaksonen M,Lacroix AZ,Lee SH,Leung PC,Lewis JR,Masi L,Mencej-Bedrac S,Nguyen TV,Nogues X,Patel MS,Prezelj J,Rose LM,Scollen S,Siggeirsdottir K,Smith AV,Svensson O,Trompet S,Trummer O,van Schoor NM,Woo J,Zhu K,Balcells S,Brandi ML,Buckley BM,Cheng S,Christiansen C,Cooper C,Dedoussis G,Ford I,Frost M,Goltzman D,Gonz?lez-Mac?as J,K?h?nen M,Karlsson M,Khusnutdinova E,Koh JM,Kollia P,Langdahl BL,Leslie WD,Lips P,Ljunggren ?,Lorenc RS,Marc J,Mellstr?m D,Obermayer-Pietsch B,Olmos JM,Pettersson-Kymmer U,Reid DM,Riancho JA,Ridker PM,Rousseau F,Slagboom PE,Tang NL,Urreizti R,Van Hul W,Viikari J,Zarrabeitia MT,Aulchenko YS,Castano-Betancourt M,Grundberg E,Herrera L,Ingvarsson T,Johannsdottir H,Kwan T,Li R,Luben R,Medina-G?mez C,Palsson ST,Reppe S,Rotter JI,Sigurdsson G,van Meurs JB,Verlaan D,Williams FM,Wood AR,Zhou Y,Gautvik KM,Pastinen T,Raychaudhuri S,Cauley JA,Chasman DI,Clark GR,Cummings SR,Danoy P,Dennison EM,Eastell R,Eisman JA,Gudnason V,Hofman A,Jackson RD,Jones G,Jukema JW,Khaw KT,Lehtim?ki T,Liu Y,Lorentzon M,McCloskey E,Mitchell BD,Nandakumar K,Nicholson GC,Oostra BA,Peacock M,Pols HA,Prince RL,Raitakari O,Reid IR,Robbins J,Sambrook PN,Sham PC,Shuldiner AR,Tylavsky FA,van Duijn CM,Wareham NJ,Cupples LA,Econs MJ,Evans DM,Harris TB,Kung AW,Psaty BM,Reeve J,Spector TD,Streeten EA,Zillikens MC,Thorsteinsdottir U,Ohlsson C,Karasik D,Richards JB,Brown MA,Stefansson K,Uitterlinden AG,Ralston SH,Ioannidis JP,Kiel DP,Rivadeneira F

A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.
Carcinogenesis33(3)598-603(2012 Mar)
Tao S,Wang Z,Feng J,Hsu FC,Jin G,Kim ST,Zhang Z,Gronberg H,Zheng LS,Isaacs WB,Xu J,Sun J

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.
Nature476(7359)214-9(2011 Aug)
,,Sawcer S,Hellenthal G,Pirinen M,Spencer CC,Patsopoulos NA,Moutsianas L,Dilthey A,Su Z,Freeman C,Hunt SE,Edkins S,Gray E,Booth DR,Potter SC,Goris A,Band G,Oturai AB,Strange A,Saarela J,Bellenguez C,Fontaine B,Gillman M,Hemmer B,Gwilliam R,Zipp F,Jayakumar A,Martin R,Leslie S,Hawkins S,Giannoulatou E,D'alfonso S,Blackburn H,Martinelli Boneschi F,Liddle J,Harbo HF,Perez ML,Spurkland A,Waller MJ,Mycko MP,Ricketts M,Comabella M,Hammond N,Kockum I,McCann OT,Ban M,Whittaker P,Kemppinen A,Weston P,Hawkins C,Widaa S,Zajicek J,Dronov S,Robertson N,Bumpstead SJ,Barcellos LF,Ravindrarajah R,Abraham R,Alfredsson L,Ardlie K,Aubin C,Baker A,Baker K,Baranzini SE,Bergamaschi L,Bergamaschi R,Bernstein A,Berthele A,Boggild M,Bradfield JP,Brassat D,Broadley SA,Buck D,Butzkueven H,Capra R,Carroll WM,Cavalla P,Celius EG,Cepok S,Chiavacci R,Clerget-Darpoux F,Clysters K,Comi G,Cossburn M,Cournu-Rebeix I,Cox MB,Cozen W,Cree BA,Cross AH,Cusi D,Daly MJ,Davis E,de Bakker PI,Debouverie M,D'hooghe MB,Dixon K,Dobosi R,Dubois B,Ellinghaus D,Elovaara I,Esposito F,Fontenille C,Foote S,Franke A,Galimberti D,Ghezzi A,Glessner J,Gomez R,Gout O,Graham C,Grant SF,Guerini FR,Hakonarson H,Hall P,Hamsten A,Hartung HP,Heard RN,Heath S,Hobart J,Hoshi M,Infante-Duarte C,Ingram G,Ingram W,Islam T,Jagodic M,Kabesch M,Kermode AG,Kilpatrick TJ,Kim C,Klopp N,Koivisto K,Larsson M,Lathrop M,Lechner-Scott JS,Leone MA,Lepp? V,Liljedahl U,Bomfim IL,Lincoln RR,Link J,Liu J,Lorentzen AR,Lupoli S,Macciardi F,Mack T,Marriott M,Martinelli V,Mason D,McCauley JL,Mentch F,Mero IL,Mihalova T,Montalban X,Mottershead J,Myhr KM,Naldi P,Ollier W,Page A,Palotie A,Pelletier J,Piccio L,Pickersgill T,Piehl F,Pobywajlo S,Quach HL,Ramsay PP,Reunanen M,Reynolds R,Rioux JD,Rodegher M,Roesner S,Rubio JP,R?ckert IM,Salvetti M,Salvi E,Santaniello A,Schaefer CA,Schreiber S,Schulze C,Scott RJ,Sellebjerg F,Selmaj KW,Sexton D,Shen L,Simms-Acuna B,Skidmore S,Sleiman PM,Smestad C,S?rensen PS,S?ndergaard HB,Stankovich J,Strange RC,Sulonen AM,Sundqvist E,Syv?nen AC,Taddeo F,Taylor B,Blackwell JM,Tienari P,Bramon E,Tourbah A,Brown MA,Tronczynska E,Casas JP,Tubridy N,Corvin A,Vickery J,Jankowski J,Villoslada P,Markus HS,Wang K,Mathew CG,Wason J,Palmer CN,Wichmann HE,Plomin R,Willoughby E,Rautanen A,Winkelmann J,Wittig M,Trembath RC,Yaouanq J,Viswanathan AC,Zhang H,Wood NW,Zuvich R,Deloukas P,Langford C,Duncanson A,Oksenberg JR,Pericak-Vance MA,Haines JL,Olsson T,Hillert J,Ivinson AJ,De Jager PL,Peltonen L,Stewart GJ,Hafler DA,Hauser SL,McVean G,Donnelly P,Compston A

The testis-specific C?2 subunit of PKA is kinetically indistinguishable from the common C?1 subunit of PKA.
BMC biochemistry1240(2011 Aug)
Vetter MM,Zenn HM,M?ndez E,van den Boom H,Herberg FW,Sk?lhegg BS

NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1.
Nature structural & molecular biology17(11)1367-76(2010 Nov)
G?ttler T,Madl T,Neumann P,Deichsel D,Corsini L,Monecke T,Ficner R,Sattler M,G?rlich D

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PKIA cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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