URGCP cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	URGCP
Entrez Gene ID	55665
Full Name	upregulator of cell proliferation
Synonyms	URG4
General protein information	Preferred Names upregulator of cell proliferation Names up-regulator of cell proliferation HBV X protein up-regulated gene 4 protein HBxAg up-regulated gene 4 protein up-regulated gene 4
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 7 Map Location: 7p13
Summary	URG4 is upregulated in the presence of hepatitis B virus (HBV)-encoded X antigen (HBxAg) and may contribute to the development of hepatocellular carcinoma by promoting hepatocellular growth and survival (Tufan et al., 2002 [PubMed 12082552]).[supplied by OMIM, Mar 2008].
Disorder MIM:	610337

mRNA and Protein(s)

mRNA	Protein	Name
NM_001077663.2	NP_001071131.1	up-regulator of cell proliferation isoform 3
NM_017920.4	NP_060390.3	up-regulator of cell proliferation isoform 1
NM_001290075.1	NP_001277004.1	up-regulator of cell proliferation isoform 2
NM_001077664.2	NP_001071132.1	up-regulator of cell proliferation isoform 2
NM_001290076.1	NP_001277005.1	up-regulator of cell proliferation isoform 2

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	URGCP	XP_853205.3
Bos taurus (cattle)	URGCP	NP_001015513.2
	URGCP	XP_001094895.1
Mus musculus (house mouse)	Urgcp	NP_848738.2
Homo sapiens (human)	URGCP	NP_001071131.1
Pan troglodytes (chimpanzee)	LOC100610816	XP_003318425.1
Rattus norvegicus (Norway rat)	Urgcp	NP_001071128.1

Gene Ontology
Bibliography

Related articles in PubMed

Downregulation of miR-16 via URGCP pathway contributes to glioma growth.
Hong L, Qing O, Ji Z, Chengqu Z, Ying C, Hao C, Minhui X, Lunshan X
Scientific reports7(1)13470(2017 Oct)

miR-519 suppresses nasopharyngeal carcinoma cell proliferation by targeting oncogene URG4/URGCP.
Yu G, Zhang T, Jing Y, Bao Q, Tang Q, Zhang Y
Life sciences17547-51(2017 Apr)

SP1 is a transcriptional regulator of URG-4/URGCP gene in hepatocytes.
Tokay E, Kockar F
Molecular and cellular biochemistry423(1-2)75-83(2016 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

miR-519 inhibited URG4 expression by directly binding to the 3'UTR of URG4. miR-519 inhibited Cyclin D1 expression and the phosphorylation level of Rb, and increased p21 and p27 expression, confirming miR-519 blocked G1/S transition.
Title: miR-519 suppresses nasopharyngeal carcinoma cell proliferation by targeting oncogene URG4/URGCP.

site-directed mutagenesis of potential SP1 binding sites diminished both DNA-protein complexes and SP1-mediated upregulation of URG-4 promoter activity. These findings are valuable for understanding transcriptional regulation of URG4/URGCP that has a pivotal role in cancer progression.
Title: SP1 is a transcriptional regulator of URG-4/URGCP gene in hepatocytes.

FA caused a decrease in the expression of novel gene URG4/URGCP.
Title: Anti-proliferative and anti-invasive effects of ferulic acid in TT medullary thyroid cancer cells interacting with URG4/URGCP.

Findings indicate that URGCP plays an important role in promoting NSCLC cell invasion and metastasis by enhancing NF-kappaB-activated MMP-9 expression
Title: URGCP promotes non-small cell lung cancer invasiveness by activating the NF-?B-MMP-9 pathway.

URG4 overexpression increased the resistance to cisplatin-induced apoptosis in bladder cancer.
Title: URGCP/URG4 promotes apoptotic resistance in bladder cancer cells by activating NF-?B signaling.

The following URGCP gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the URGCP cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu12546	NM_001290075.1 Latest version!	Homo sapiens upregulator of cell proliferation (URGCP), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$265.30 $379.00
OHu12546	NM_001077664.2 Latest version!	Homo sapiens upregulator of cell proliferation (URGCP), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$265.30 $379.00
OHu12546	NM_001290076.1 Latest version!	Homo sapiens upregulator of cell proliferation (URGCP), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$265.30 $379.00
OHu12812	NM_001077663.2 Latest version!	Homo sapiens upregulator of cell proliferation (URGCP), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$657.30 $939.00
OHu12930	NM_017920.4 Latest version!	Homo sapiens upregulator of cell proliferation (URGCP), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

URGCP ( NM_001290075.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001277004.1 Homo sapiens upregulator of cell proliferation (URGCP), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu12546
Clone ID Related Accession (Same CDS sequence)	NM_001290075.1 , NM_001077664.2 , NM_001290076.1
Accession Version	NM_001290075.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2667bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-15
Organism	Homo sapiens(human)
Product	up-regulator of cell proliferation isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA494692.1, AC004985.2, CR749398.1, AB040940.1 and AK000661.1. Transcript Variant: This variant (5) differs in the 5' UTR and lacks a portion of the 5' coding region, compared to variant 3. The 5'-most initiation codon, as used in variant 3, is associated with a truncated ORF that would render the transcript a candidate for nonsense-mediated decay (NMD). Leaky scanning may allow translation initiation at the downstream AUG resulting in an isoform (2) with a shorter N-terminus compared to isoform 3. Variants 2, 4, and 5 encode the same protein (isoform 2). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.30463.1, SRR1660809.132672.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END##

ATGGAAGGAG ATGATTGCGA GTTCCGTTAT GGAGATGGTA CAAATGAGGC TCAGGACAAT 
GATTTTCCAA CAGTGGAGAG AAGCAGGCTT CAAGAAATGC TGTCACTTTT GGGCCTAGAG 
ACGTACCAGG TCCAGAAACT CAGCCTCCAG GACTCTCTGC AGATCAGTTT TGACAGTATG 
AAGAACTGGG CCCCTCAGGT TCCCAAAGAC TTGCCCTGGA ATTTCCTCAG GAAGTTGCAG 
GCCCTCAATG CTGATGCCAG GAATACCACT ATGGTGCTGG ACGTGCTCCC AGACGCCAGG 
CCTGTGGAGA AGGAGAGCCA GATGGAAGAG GAGATCATCT ACTGGGACCC AGCTGATGAC 
CTTGCTGCCG ACATTTATTC CTTTTCTGAG CTGCCCACCC CTGATACGCC AGTGAACCCC 
TTAGACCTTC TCTGTGCCCT GCTGCTCTCC TCAGACAGTT TCCTGCAACA AGAAATAGCG 
TTGAAAATGG CCCTCTGCCA GTTTGCACTC CCACTCGTGT TGCCTGACTC GGAGAACCAC 
TACCATACAT TTCTGCTGTG GGCCATGCGG GGCATTGTGA GGACATGGTG GTCCCAGCCC 
CCAAGGGGCA TGGGGAGCTT CCGGGAAGAC AGCGTGGTCT TGTCCAGGGC GCCCGCCTTC 
GCCTTCGTGC GCATGGACGT CAGTAGCAAC TCCAAGTCCC AGCTTCTCAA CGCCGTCCTC 
AGCCCGGGCC ACAGGCAGTG GGACTGCTTC TGGCATCGGG ACCTCAACTT GGGCACCAAT 
GCCCGGGAGA TTTCGGATGG GTTGGTAGAA ATTTCCTGGT TTTTTCCCAG CGGAAGGGAG 
GACTTGGACA TTTTCCCAGA ACCTGTGGCC TTTCTGAACC TGAGAGGTGA CATCGGGTCT 
CACTGGCTGC AGTTTAAGCT CTTGACAGAA ATCTCCTCCG CTGTGTTTAT ATTGACTGAC 
AATATCAGTA AGAAGGAATA CAAATTGCTG TACTCCATGA AGGAGTCAAC CACAAAATAC 
TACTTCATCC TGAGTCCCTA CCGTGGGAAG CGCAACACAA ACCTGAGATT TCTGAATAAG 
TTAATTCCTG TGCTGAAAAT AGACCACTCA CATGTCCTGG TAAAGGTCAG CAGCACTGAC 
AGCGACAGCT TCGTGAAGAG GATCCGGGCC ATCGTTGGGA ATGTGCTGCG GGCACCCTGC 
AGGCGGGTAT CTGTGGAGGA CATGGCGCAC GCAGCCCGCA AACTGGGCCT AAAGGTCGAC 
GAGGACTGTG AGGAGTGTCA GAAAGCGAAA GACCGGATGG AGAGGATTAC CAGGAAAATC 
AAAGACTCGG ATGCCTACAG AAGGGACGAG CTGAGGCTGC AGGGGGACCC CTGGAGAAAG 
GCAGCCCAAG TGGAGAAGGA GTTCTGCCAG CTCCAGTGGG CCGTGGACCC CCCTGAGAAG 
CACAGGGCTG AGCTGAGGCG GCGGCTGCTA GAACTTCGAA TGCAGCAGAA CGGCCATGAT 
CCCTCCTCGG GGGTGCAGGA GTTCATCTCG GGGATCAGCA GCCCCTCCTT GAGTGAGAAG 
CAGTACTTCC TGAGGTGGAT GGAGTGGGGC CTGGCACGGG TGGCCCAGCC GCGACTGAGA 
CAGCCTCCGG AGACGCTTCT CACCCTGAGA CCAAAGCATG GGGGCACCAC AGACGTGGGG 
GAGCCGCTCT GGCCTGAGCC CCTAGGGGTG GAACACTTCT TGCGGGAGAT GGGACAGTTT 
TATGAGGCTG AGAGCTGTCT TGTGGAGGCA GGGAGGCTGC CGGCAGGCCA GAGGCGTTTT 
GCCCACTTCC CAGGCTTGGC CTCGGAGCTG CTGCTGACAG GGCTGCCTCT GGAGCTAATC 
GATGGGAGCA CGCTGAGCAT GCCCGTCCGC TGGGTCACAG GGCTCCTGAA GGAGCTGCAC 
GTCCGACTGG AGAGACGGTC AAGGCTGGTG GTTCTGTCAA CCGTCGGGGT GCCAGGCACG 
GGCAAGTCCA CACTCCTCAA CACCATGTTT GGGCTGCGGT TTGCCACAGG GAAGAGCTGC 
GGTCCTCGAG GGGCCTTCAT GCAGCTCATC ACAGTGGCTG AGGGCTTCAG CCAGGACCTG 
GGCTGTGACC ACATCCTGGT GATAGACTCC GGGGGCTTGA TAGGTGGGGC CTTGACGTCA 
GCTGGGGACA GATTTGAGCT GGAGGCTTCC TTGGCCACTC TGCTCATGGG ACTGAGCAAT 
GTCACCGTGA TCAGTCTAGC TGAAACCAAG GACATTCCAG CAGCTATTCT GCATGCATTT 
CTGAGGTTAG AAAAAACGGG GCACATGCCC AACTACCAGT TTGTATACCA GAACCTTCAT 
GATGTATCTG TTCCCGGCCC TAGGCCCAGA GACAAGAGAC AGCTCCTGGA TCCACCTGGT 
GACCTGAGCA GGGCTGCAGC CCAGATGGAG AAACAGGGCG ACGGCTTCCG GGCACTGGCA 
GGCCTGGCCT TCTGCGACCC TGAGAAGCAG CACATCTGGC ACATCCCAGG CCTGTGGCAC 
GGAGCACCTC CCATGGCCGC AGTGAGCTTG GCCTACAGTG AAGCCATATT TGAATTGAAG 
AGATGCCTAC TCGAAAACAT CAGGAACGGC TTGTCGAACC AAAACAAAAA CATCCAGCAG 
CTCATTGAGC TGGTGAGACG GCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001277004.1
CDS	619..3285
Translation	MEGDDCEFRYGDGTNEAQDNDFPTVERSRLQEMLSLLGLETYQVQKLSLQDSLQISFDSMKNWAPQVPKDLPWNFLRKLQALNADARNTTMVLDVLPDARPVEKESQMEEEIIYWDPADDLAADIYSFSELPTPDTPVNPLDLLCALLLSSDSFLQQEIALKMALCQFALPLVLPDSENHYHTFLLWAMRGIVRTWWSQPPRGMGSFREDSVVLSRAPAFAFVRMDVSSNSKSQLLNAVLSPGHRQWDCFWHRDLNLGTNAREISDGLVEISWFFPSGREDLDIFPEPVAFLNLRGDIGSHWLQFKLLTEISSAVFILTDNISKKEYKLLYSMKESTTKYYFILSPYRGKRNTNLRFLNKLIPVLKIDHSHVLVKVSSTDSDSFVKRIRAIVGNVLRAPCRRVSVEDMAHAARKLGLKVDEDCEECQKAKDRMERITRKIKDSDAYRRDELRLQGDPWRKAAQVEKEFCQLQWAVDPPEKHRAELRRRLLELRMQQNGHDPSSGVQEFISGISSPSLSEKQYFLRWMEWGLARVAQPRLRQPPETLLTLRPKHGGTTDVGEPLWPEPLGVEHFLREMGQFYEAESCLVEAGRLPAGQRRFAHFPGLASELLLTGLPLELIDGSTLSMPVRWVTGLLKELHVRLERRSRLVVLSTVGVPGTGKSTLLNTMFGLRFATGKSCGPRGAFMQLITVAEGFSQDLGCDHILVIDSGGLIGGALTSAGDRFELEASLATLLMGLSNVTVISLAETKDIPAAILHAFLRLEKTGHMPNYQFVYQNLHDVSVPGPRPRDKRQLLDPPGDLSRAAAQMEKQGDGFRALAGLAFCDPEKQHIWHIPGLWHGAPPMAAVSLAYSEAIFELKRCLLENIRNGLSNQNKNIQQLIELVRRL

Target ORF information:

RefSeq Version	NM_001290075.1
Organism	Homo sapiens(human)
Definition	Homo sapiens upregulator of cell proliferation (URGCP), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001290075.1

ORF Insert Sequence:

ATGGAAGGAG ATGATTGCGA GTTCCGTTAT GGAGATGGTA CAAATGAGGC TCAGGACAAT 
GATTTTCCAA CAGTGGAGAG AAGCAGGCTT CAAGAAATGC TGTCACTTTT GGGCCTAGAG 
ACGTACCAGG TCCAGAAACT CAGCCTCCAG GACTCTCTGC AGATCAGTTT TGACAGTATG 
AAGAACTGGG CCCCTCAGGT TCCCAAAGAC TTGCCCTGGA ATTTCCTCAG GAAGTTGCAG 
GCCCTCAATG CTGATGCCAG GAATACCACT ATGGTGCTGG ACGTGCTCCC AGACGCCAGG 
CCTGTGGAGA AGGAGAGCCA GATGGAAGAG GAGATCATCT ACTGGGACCC AGCTGATGAC 
CTTGCTGCCG ACATTTATTC CTTTTCTGAG CTGCCCACCC CTGATACGCC AGTGAACCCC 
TTAGACCTTC TCTGTGCCCT GCTGCTCTCC TCAGACAGTT TCCTGCAACA AGAAATAGCG 
TTGAAAATGG CCCTCTGCCA GTTTGCACTC CCACTCGTGT TGCCTGACTC GGAGAACCAC 
TACCATACAT TTCTGCTGTG GGCCATGCGG GGCATTGTGA GGACATGGTG GTCCCAGCCC 
CCAAGGGGCA TGGGGAGCTT CCGGGAAGAC AGCGTGGTCT TGTCCAGGGC GCCCGCCTTC 
GCCTTCGTGC GCATGGACGT CAGTAGCAAC TCCAAGTCCC AGCTTCTCAA CGCCGTCCTC 
AGCCCGGGCC ACAGGCAGTG GGACTGCTTC TGGCATCGGG ACCTCAACTT GGGCACCAAT 
GCCCGGGAGA TTTCGGATGG GTTGGTAGAA ATTTCCTGGT TTTTTCCCAG CGGAAGGGAG 
GACTTGGACA TTTTCCCAGA ACCTGTGGCC TTTCTGAACC TGAGAGGTGA CATCGGGTCT 
CACTGGCTGC AGTTTAAGCT CTTGACAGAA ATCTCCTCCG CTGTGTTTAT ATTGACTGAC 
AATATCAGTA AGAAGGAATA CAAATTGCTG TACTCCATGA AGGAGTCAAC CACAAAATAC 
TACTTCATCC TGAGTCCCTA CCGTGGGAAG CGCAACACAA ACCTGAGATT TCTGAATAAG 
TTAATTCCTG TGCTGAAAAT AGACCACTCA CATGTCCTGG TAAAGGTCAG CAGCACTGAC 
AGCGACAGCT TCGTGAAGAG GATCCGGGCC ATCGTTGGGA ATGTGCTGCG GGCACCCTGC 
AGGCGGGTAT CTGTGGAGGA CATGGCGCAC GCAGCCCGCA AACTGGGCCT AAAGGTCGAC 
GAGGACTGTG AGGAGTGTCA GAAAGCGAAA GACCGGATGG AGAGGATTAC CAGGAAAATC 
AAAGACTCGG ATGCCTACAG AAGGGACGAG CTGAGGCTGC AGGGGGACCC CTGGAGAAAG 
GCAGCCCAAG TGGAGAAGGA GTTCTGCCAG CTCCAGTGGG CCGTGGACCC CCCTGAGAAG 
CACAGGGCTG AGCTGAGGCG GCGGCTGCTA GAACTTCGAA TGCAGCAGAA CGGCCATGAT 
CCCTCCTCGG GGGTGCAGGA GTTCATCTCG GGGATCAGCA GCCCCTCCTT GAGTGAGAAG 
CAGTACTTCC TGAGGTGGAT GGAGTGGGGC CTGGCACGGG TGGCCCAGCC GCGACTGAGA 
CAGCCTCCGG AGACGCTTCT CACCCTGAGA CCAAAGCATG GGGGCACCAC AGACGTGGGG 
GAGCCGCTCT GGCCTGAGCC CCTAGGGGTG GAACACTTCT TGCGGGAGAT GGGACAGTTT 
TATGAGGCTG AGAGCTGTCT TGTGGAGGCA GGGAGGCTGC CGGCAGGCCA GAGGCGTTTT 
GCCCACTTCC CAGGCTTGGC CTCGGAGCTG CTGCTGACAG GGCTGCCTCT GGAGCTAATC 
GATGGGAGCA CGCTGAGCAT GCCCGTCCGC TGGGTCACAG GGCTCCTGAA GGAGCTGCAC 
GTCCGACTGG AGAGACGGTC AAGGCTGGTG GTTCTGTCAA CCGTCGGGGT GCCAGGCACG 
GGCAAGTCCA CACTCCTCAA CACCATGTTT GGGCTGCGGT TTGCCACAGG GAAGAGCTGC 
GGTCCTCGAG GGGCCTTCAT GCAGCTCATC ACAGTGGCTG AGGGCTTCAG CCAGGACCTG 
GGCTGTGACC ACATCCTGGT GATAGACTCC GGGGGCTTGA TAGGTGGGGC CTTGACGTCA 
GCTGGGGACA GATTTGAGCT GGAGGCTTCC TTGGCCACTC TGCTCATGGG ACTGAGCAAT 
GTCACCGTGA TCAGTCTAGC TGAAACCAAG GACATTCCAG CAGCTATTCT GCATGCATTT 
CTGAGGTTAG AAAAAACGGG GCACATGCCC AACTACCAGT TTGTATACCA GAACCTTCAT 
GATGTATCTG TTCCCGGCCC TAGGCCCAGA GACAAGAGAC AGCTCCTGGA TCCACCTGGT 
GACCTGAGCA GGGCTGCAGC CCAGATGGAG AAACAGGGCG ACGGCTTCCG GGCACTGGCA 
GGCCTGGCCT TCTGCGACCC TGAGAAGCAG CACATCTGGC ACATCCCAGG CCTGTGGCAC 
GGAGCACCTC CCATGGCCGC AGTGAGCTTG GCCTACAGTG AAGCCATATT TGAATTGAAG 
AGATGCCTAC TCGAAAACAT CAGGAACGGC TTGTCGAACC AAAACAAAAA CATCCAGCAG 
CTCATTGAGC TGGTGAGACG GCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

URGCP ( NM_001077664.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001071132.1 Homo sapiens upregulator of cell proliferation (URGCP), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu12546
Clone ID Related Accession (Same CDS sequence)	NM_001290075.1 , NM_001077664.2 , NM_001290076.1
Accession Version	NM_001077664.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2667bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-15
Organism	Homo sapiens(human)
Product	up-regulator of cell proliferation isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DC336174.1, AB040940.1 and AK000661.1. On Feb 22, 2014 this sequence version replaced NM_001077664.1. Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation from a downstream start codon, compared to variant 3. The encoded protein (isoform 2) has a shorter N-terminus, compared to isoform 3. Variants 2, 4, and 5 encode the same protein (isoform 2). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DC335643.1, SRR1803612.230598.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGAAGGAG ATGATTGCGA GTTCCGTTAT GGAGATGGTA CAAATGAGGC TCAGGACAAT 
GATTTTCCAA CAGTGGAGAG AAGCAGGCTT CAAGAAATGC TGTCACTTTT GGGCCTAGAG 
ACGTACCAGG TCCAGAAACT CAGCCTCCAG GACTCTCTGC AGATCAGTTT TGACAGTATG 
AAGAACTGGG CCCCTCAGGT TCCCAAAGAC TTGCCCTGGA ATTTCCTCAG GAAGTTGCAG 
GCCCTCAATG CTGATGCCAG GAATACCACT ATGGTGCTGG ACGTGCTCCC AGACGCCAGG 
CCTGTGGAGA AGGAGAGCCA GATGGAAGAG GAGATCATCT ACTGGGACCC AGCTGATGAC 
CTTGCTGCCG ACATTTATTC CTTTTCTGAG CTGCCCACCC CTGATACGCC AGTGAACCCC 
TTAGACCTTC TCTGTGCCCT GCTGCTCTCC TCAGACAGTT TCCTGCAACA AGAAATAGCG 
TTGAAAATGG CCCTCTGCCA GTTTGCACTC CCACTCGTGT TGCCTGACTC GGAGAACCAC 
TACCATACAT TTCTGCTGTG GGCCATGCGG GGCATTGTGA GGACATGGTG GTCCCAGCCC 
CCAAGGGGCA TGGGGAGCTT CCGGGAAGAC AGCGTGGTCT TGTCCAGGGC GCCCGCCTTC 
GCCTTCGTGC GCATGGACGT CAGTAGCAAC TCCAAGTCCC AGCTTCTCAA CGCCGTCCTC 
AGCCCGGGCC ACAGGCAGTG GGACTGCTTC TGGCATCGGG ACCTCAACTT GGGCACCAAT 
GCCCGGGAGA TTTCGGATGG GTTGGTAGAA ATTTCCTGGT TTTTTCCCAG CGGAAGGGAG 
GACTTGGACA TTTTCCCAGA ACCTGTGGCC TTTCTGAACC TGAGAGGTGA CATCGGGTCT 
CACTGGCTGC AGTTTAAGCT CTTGACAGAA ATCTCCTCCG CTGTGTTTAT ATTGACTGAC 
AATATCAGTA AGAAGGAATA CAAATTGCTG TACTCCATGA AGGAGTCAAC CACAAAATAC 
TACTTCATCC TGAGTCCCTA CCGTGGGAAG CGCAACACAA ACCTGAGATT TCTGAATAAG 
TTAATTCCTG TGCTGAAAAT AGACCACTCA CATGTCCTGG TAAAGGTCAG CAGCACTGAC 
AGCGACAGCT TCGTGAAGAG GATCCGGGCC ATCGTTGGGA ATGTGCTGCG GGCACCCTGC 
AGGCGGGTAT CTGTGGAGGA CATGGCGCAC GCAGCCCGCA AACTGGGCCT AAAGGTCGAC 
GAGGACTGTG AGGAGTGTCA GAAAGCGAAA GACCGGATGG AGAGGATTAC CAGGAAAATC 
AAAGACTCGG ATGCCTACAG AAGGGACGAG CTGAGGCTGC AGGGGGACCC CTGGAGAAAG 
GCAGCCCAAG TGGAGAAGGA GTTCTGCCAG CTCCAGTGGG CCGTGGACCC CCCTGAGAAG 
CACAGGGCTG AGCTGAGGCG GCGGCTGCTA GAACTTCGAA TGCAGCAGAA CGGCCATGAT 
CCCTCCTCGG GGGTGCAGGA GTTCATCTCG GGGATCAGCA GCCCCTCCTT GAGTGAGAAG 
CAGTACTTCC TGAGGTGGAT GGAGTGGGGC CTGGCACGGG TGGCCCAGCC GCGACTGAGA 
CAGCCTCCGG AGACGCTTCT CACCCTGAGA CCAAAGCATG GGGGCACCAC AGACGTGGGG 
GAGCCGCTCT GGCCTGAGCC CCTAGGGGTG GAACACTTCT TGCGGGAGAT GGGACAGTTT 
TATGAGGCTG AGAGCTGTCT TGTGGAGGCA GGGAGGCTGC CGGCAGGCCA GAGGCGTTTT 
GCCCACTTCC CAGGCTTGGC CTCGGAGCTG CTGCTGACAG GGCTGCCTCT GGAGCTAATC 
GATGGGAGCA CGCTGAGCAT GCCCGTCCGC TGGGTCACAG GGCTCCTGAA GGAGCTGCAC 
GTCCGACTGG AGAGACGGTC AAGGCTGGTG GTTCTGTCAA CCGTCGGGGT GCCAGGCACG 
GGCAAGTCCA CACTCCTCAA CACCATGTTT GGGCTGCGGT TTGCCACAGG GAAGAGCTGC 
GGTCCTCGAG GGGCCTTCAT GCAGCTCATC ACAGTGGCTG AGGGCTTCAG CCAGGACCTG 
GGCTGTGACC ACATCCTGGT GATAGACTCC GGGGGCTTGA TAGGTGGGGC CTTGACGTCA 
GCTGGGGACA GATTTGAGCT GGAGGCTTCC TTGGCCACTC TGCTCATGGG ACTGAGCAAT 
GTCACCGTGA TCAGTCTAGC TGAAACCAAG GACATTCCAG CAGCTATTCT GCATGCATTT 
CTGAGGTTAG AAAAAACGGG GCACATGCCC AACTACCAGT TTGTATACCA GAACCTTCAT 
GATGTATCTG TTCCCGGCCC TAGGCCCAGA GACAAGAGAC AGCTCCTGGA TCCACCTGGT 
GACCTGAGCA GGGCTGCAGC CCAGATGGAG AAACAGGGCG ACGGCTTCCG GGCACTGGCA 
GGCCTGGCCT TCTGCGACCC TGAGAAGCAG CACATCTGGC ACATCCCAGG CCTGTGGCAC 
GGAGCACCTC CCATGGCCGC AGTGAGCTTG GCCTACAGTG AAGCCATATT TGAATTGAAG 
AGATGCCTAC TCGAAAACAT CAGGAACGGC TTGTCGAACC AAAACAAAAA CATCCAGCAG 
CTCATTGAGC TGGTGAGACG GCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001071132.1
CDS	396..3062
Translation	MEGDDCEFRYGDGTNEAQDNDFPTVERSRLQEMLSLLGLETYQVQKLSLQDSLQISFDSMKNWAPQVPKDLPWNFLRKLQALNADARNTTMVLDVLPDARPVEKESQMEEEIIYWDPADDLAADIYSFSELPTPDTPVNPLDLLCALLLSSDSFLQQEIALKMALCQFALPLVLPDSENHYHTFLLWAMRGIVRTWWSQPPRGMGSFREDSVVLSRAPAFAFVRMDVSSNSKSQLLNAVLSPGHRQWDCFWHRDLNLGTNAREISDGLVEISWFFPSGREDLDIFPEPVAFLNLRGDIGSHWLQFKLLTEISSAVFILTDNISKKEYKLLYSMKESTTKYYFILSPYRGKRNTNLRFLNKLIPVLKIDHSHVLVKVSSTDSDSFVKRIRAIVGNVLRAPCRRVSVEDMAHAARKLGLKVDEDCEECQKAKDRMERITRKIKDSDAYRRDELRLQGDPWRKAAQVEKEFCQLQWAVDPPEKHRAELRRRLLELRMQQNGHDPSSGVQEFISGISSPSLSEKQYFLRWMEWGLARVAQPRLRQPPETLLTLRPKHGGTTDVGEPLWPEPLGVEHFLREMGQFYEAESCLVEAGRLPAGQRRFAHFPGLASELLLTGLPLELIDGSTLSMPVRWVTGLLKELHVRLERRSRLVVLSTVGVPGTGKSTLLNTMFGLRFATGKSCGPRGAFMQLITVAEGFSQDLGCDHILVIDSGGLIGGALTSAGDRFELEASLATLLMGLSNVTVISLAETKDIPAAILHAFLRLEKTGHMPNYQFVYQNLHDVSVPGPRPRDKRQLLDPPGDLSRAAAQMEKQGDGFRALAGLAFCDPEKQHIWHIPGLWHGAPPMAAVSLAYSEAIFELKRCLLENIRNGLSNQNKNIQQLIELVRRL

Target ORF information:

RefSeq Version	NM_001077664.2
Organism	Homo sapiens(human)
Definition	Homo sapiens upregulator of cell proliferation (URGCP), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001077664.2

ORF Insert Sequence:

ATGGAAGGAG ATGATTGCGA GTTCCGTTAT GGAGATGGTA CAAATGAGGC TCAGGACAAT 
GATTTTCCAA CAGTGGAGAG AAGCAGGCTT CAAGAAATGC TGTCACTTTT GGGCCTAGAG 
ACGTACCAGG TCCAGAAACT CAGCCTCCAG GACTCTCTGC AGATCAGTTT TGACAGTATG 
AAGAACTGGG CCCCTCAGGT TCCCAAAGAC TTGCCCTGGA ATTTCCTCAG GAAGTTGCAG 
GCCCTCAATG CTGATGCCAG GAATACCACT ATGGTGCTGG ACGTGCTCCC AGACGCCAGG 
CCTGTGGAGA AGGAGAGCCA GATGGAAGAG GAGATCATCT ACTGGGACCC AGCTGATGAC 
CTTGCTGCCG ACATTTATTC CTTTTCTGAG CTGCCCACCC CTGATACGCC AGTGAACCCC 
TTAGACCTTC TCTGTGCCCT GCTGCTCTCC TCAGACAGTT TCCTGCAACA AGAAATAGCG 
TTGAAAATGG CCCTCTGCCA GTTTGCACTC CCACTCGTGT TGCCTGACTC GGAGAACCAC 
TACCATACAT TTCTGCTGTG GGCCATGCGG GGCATTGTGA GGACATGGTG GTCCCAGCCC 
CCAAGGGGCA TGGGGAGCTT CCGGGAAGAC AGCGTGGTCT TGTCCAGGGC GCCCGCCTTC 
GCCTTCGTGC GCATGGACGT CAGTAGCAAC TCCAAGTCCC AGCTTCTCAA CGCCGTCCTC 
AGCCCGGGCC ACAGGCAGTG GGACTGCTTC TGGCATCGGG ACCTCAACTT GGGCACCAAT 
GCCCGGGAGA TTTCGGATGG GTTGGTAGAA ATTTCCTGGT TTTTTCCCAG CGGAAGGGAG 
GACTTGGACA TTTTCCCAGA ACCTGTGGCC TTTCTGAACC TGAGAGGTGA CATCGGGTCT 
CACTGGCTGC AGTTTAAGCT CTTGACAGAA ATCTCCTCCG CTGTGTTTAT ATTGACTGAC 
AATATCAGTA AGAAGGAATA CAAATTGCTG TACTCCATGA AGGAGTCAAC CACAAAATAC 
TACTTCATCC TGAGTCCCTA CCGTGGGAAG CGCAACACAA ACCTGAGATT TCTGAATAAG 
TTAATTCCTG TGCTGAAAAT AGACCACTCA CATGTCCTGG TAAAGGTCAG CAGCACTGAC 
AGCGACAGCT TCGTGAAGAG GATCCGGGCC ATCGTTGGGA ATGTGCTGCG GGCACCCTGC 
AGGCGGGTAT CTGTGGAGGA CATGGCGCAC GCAGCCCGCA AACTGGGCCT AAAGGTCGAC 
GAGGACTGTG AGGAGTGTCA GAAAGCGAAA GACCGGATGG AGAGGATTAC CAGGAAAATC 
AAAGACTCGG ATGCCTACAG AAGGGACGAG CTGAGGCTGC AGGGGGACCC CTGGAGAAAG 
GCAGCCCAAG TGGAGAAGGA GTTCTGCCAG CTCCAGTGGG CCGTGGACCC CCCTGAGAAG 
CACAGGGCTG AGCTGAGGCG GCGGCTGCTA GAACTTCGAA TGCAGCAGAA CGGCCATGAT 
CCCTCCTCGG GGGTGCAGGA GTTCATCTCG GGGATCAGCA GCCCCTCCTT GAGTGAGAAG 
CAGTACTTCC TGAGGTGGAT GGAGTGGGGC CTGGCACGGG TGGCCCAGCC GCGACTGAGA 
CAGCCTCCGG AGACGCTTCT CACCCTGAGA CCAAAGCATG GGGGCACCAC AGACGTGGGG 
GAGCCGCTCT GGCCTGAGCC CCTAGGGGTG GAACACTTCT TGCGGGAGAT GGGACAGTTT 
TATGAGGCTG AGAGCTGTCT TGTGGAGGCA GGGAGGCTGC CGGCAGGCCA GAGGCGTTTT 
GCCCACTTCC CAGGCTTGGC CTCGGAGCTG CTGCTGACAG GGCTGCCTCT GGAGCTAATC 
GATGGGAGCA CGCTGAGCAT GCCCGTCCGC TGGGTCACAG GGCTCCTGAA GGAGCTGCAC 
GTCCGACTGG AGAGACGGTC AAGGCTGGTG GTTCTGTCAA CCGTCGGGGT GCCAGGCACG 
GGCAAGTCCA CACTCCTCAA CACCATGTTT GGGCTGCGGT TTGCCACAGG GAAGAGCTGC 
GGTCCTCGAG GGGCCTTCAT GCAGCTCATC ACAGTGGCTG AGGGCTTCAG CCAGGACCTG 
GGCTGTGACC ACATCCTGGT GATAGACTCC GGGGGCTTGA TAGGTGGGGC CTTGACGTCA 
GCTGGGGACA GATTTGAGCT GGAGGCTTCC TTGGCCACTC TGCTCATGGG ACTGAGCAAT 
GTCACCGTGA TCAGTCTAGC TGAAACCAAG GACATTCCAG CAGCTATTCT GCATGCATTT 
CTGAGGTTAG AAAAAACGGG GCACATGCCC AACTACCAGT TTGTATACCA GAACCTTCAT 
GATGTATCTG TTCCCGGCCC TAGGCCCAGA GACAAGAGAC AGCTCCTGGA TCCACCTGGT 
GACCTGAGCA GGGCTGCAGC CCAGATGGAG AAACAGGGCG ACGGCTTCCG GGCACTGGCA 
GGCCTGGCCT TCTGCGACCC TGAGAAGCAG CACATCTGGC ACATCCCAGG CCTGTGGCAC 
GGAGCACCTC CCATGGCCGC AGTGAGCTTG GCCTACAGTG AAGCCATATT TGAATTGAAG 
AGATGCCTAC TCGAAAACAT CAGGAACGGC TTGTCGAACC AAAACAAAAA CATCCAGCAG 
CTCATTGAGC TGGTGAGACG GCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

URGCP ( NM_001290076.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001277005.1 Homo sapiens upregulator of cell proliferation (URGCP), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu12546
Clone ID Related Accession (Same CDS sequence)	NM_001290075.1 , NM_001077664.2 , NM_001290076.1
Accession Version	NM_001290076.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2667bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-15
Organism	Homo sapiens(human)
Product	up-regulator of cell proliferation isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK302459.1, AK314339.1, AB040940.1 and AK000661.1. Transcript Variant: This variant (4) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation from a downstream start codon, compared to variant 3. The encoded protein (isoform 2) has a shorter N-terminus, compared to isoform 3. Variants 2, 4, and 5 encode the same protein (isoform 2). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK302459.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END##

ATGGAAGGAG ATGATTGCGA GTTCCGTTAT GGAGATGGTA CAAATGAGGC TCAGGACAAT 
GATTTTCCAA CAGTGGAGAG AAGCAGGCTT CAAGAAATGC TGTCACTTTT GGGCCTAGAG 
ACGTACCAGG TCCAGAAACT CAGCCTCCAG GACTCTCTGC AGATCAGTTT TGACAGTATG 
AAGAACTGGG CCCCTCAGGT TCCCAAAGAC TTGCCCTGGA ATTTCCTCAG GAAGTTGCAG 
GCCCTCAATG CTGATGCCAG GAATACCACT ATGGTGCTGG ACGTGCTCCC AGACGCCAGG 
CCTGTGGAGA AGGAGAGCCA GATGGAAGAG GAGATCATCT ACTGGGACCC AGCTGATGAC 
CTTGCTGCCG ACATTTATTC CTTTTCTGAG CTGCCCACCC CTGATACGCC AGTGAACCCC 
TTAGACCTTC TCTGTGCCCT GCTGCTCTCC TCAGACAGTT TCCTGCAACA AGAAATAGCG 
TTGAAAATGG CCCTCTGCCA GTTTGCACTC CCACTCGTGT TGCCTGACTC GGAGAACCAC 
TACCATACAT TTCTGCTGTG GGCCATGCGG GGCATTGTGA GGACATGGTG GTCCCAGCCC 
CCAAGGGGCA TGGGGAGCTT CCGGGAAGAC AGCGTGGTCT TGTCCAGGGC GCCCGCCTTC 
GCCTTCGTGC GCATGGACGT CAGTAGCAAC TCCAAGTCCC AGCTTCTCAA CGCCGTCCTC 
AGCCCGGGCC ACAGGCAGTG GGACTGCTTC TGGCATCGGG ACCTCAACTT GGGCACCAAT 
GCCCGGGAGA TTTCGGATGG GTTGGTAGAA ATTTCCTGGT TTTTTCCCAG CGGAAGGGAG 
GACTTGGACA TTTTCCCAGA ACCTGTGGCC TTTCTGAACC TGAGAGGTGA CATCGGGTCT 
CACTGGCTGC AGTTTAAGCT CTTGACAGAA ATCTCCTCCG CTGTGTTTAT ATTGACTGAC 
AATATCAGTA AGAAGGAATA CAAATTGCTG TACTCCATGA AGGAGTCAAC CACAAAATAC 
TACTTCATCC TGAGTCCCTA CCGTGGGAAG CGCAACACAA ACCTGAGATT TCTGAATAAG 
TTAATTCCTG TGCTGAAAAT AGACCACTCA CATGTCCTGG TAAAGGTCAG CAGCACTGAC 
AGCGACAGCT TCGTGAAGAG GATCCGGGCC ATCGTTGGGA ATGTGCTGCG GGCACCCTGC 
AGGCGGGTAT CTGTGGAGGA CATGGCGCAC GCAGCCCGCA AACTGGGCCT AAAGGTCGAC 
GAGGACTGTG AGGAGTGTCA GAAAGCGAAA GACCGGATGG AGAGGATTAC CAGGAAAATC 
AAAGACTCGG ATGCCTACAG AAGGGACGAG CTGAGGCTGC AGGGGGACCC CTGGAGAAAG 
GCAGCCCAAG TGGAGAAGGA GTTCTGCCAG CTCCAGTGGG CCGTGGACCC CCCTGAGAAG 
CACAGGGCTG AGCTGAGGCG GCGGCTGCTA GAACTTCGAA TGCAGCAGAA CGGCCATGAT 
CCCTCCTCGG GGGTGCAGGA GTTCATCTCG GGGATCAGCA GCCCCTCCTT GAGTGAGAAG 
CAGTACTTCC TGAGGTGGAT GGAGTGGGGC CTGGCACGGG TGGCCCAGCC GCGACTGAGA 
CAGCCTCCGG AGACGCTTCT CACCCTGAGA CCAAAGCATG GGGGCACCAC AGACGTGGGG 
GAGCCGCTCT GGCCTGAGCC CCTAGGGGTG GAACACTTCT TGCGGGAGAT GGGACAGTTT 
TATGAGGCTG AGAGCTGTCT TGTGGAGGCA GGGAGGCTGC CGGCAGGCCA GAGGCGTTTT 
GCCCACTTCC CAGGCTTGGC CTCGGAGCTG CTGCTGACAG GGCTGCCTCT GGAGCTAATC 
GATGGGAGCA CGCTGAGCAT GCCCGTCCGC TGGGTCACAG GGCTCCTGAA GGAGCTGCAC 
GTCCGACTGG AGAGACGGTC AAGGCTGGTG GTTCTGTCAA CCGTCGGGGT GCCAGGCACG 
GGCAAGTCCA CACTCCTCAA CACCATGTTT GGGCTGCGGT TTGCCACAGG GAAGAGCTGC 
GGTCCTCGAG GGGCCTTCAT GCAGCTCATC ACAGTGGCTG AGGGCTTCAG CCAGGACCTG 
GGCTGTGACC ACATCCTGGT GATAGACTCC GGGGGCTTGA TAGGTGGGGC CTTGACGTCA 
GCTGGGGACA GATTTGAGCT GGAGGCTTCC TTGGCCACTC TGCTCATGGG ACTGAGCAAT 
GTCACCGTGA TCAGTCTAGC TGAAACCAAG GACATTCCAG CAGCTATTCT GCATGCATTT 
CTGAGGTTAG AAAAAACGGG GCACATGCCC AACTACCAGT TTGTATACCA GAACCTTCAT 
GATGTATCTG TTCCCGGCCC TAGGCCCAGA GACAAGAGAC AGCTCCTGGA TCCACCTGGT 
GACCTGAGCA GGGCTGCAGC CCAGATGGAG AAACAGGGCG ACGGCTTCCG GGCACTGGCA 
GGCCTGGCCT TCTGCGACCC TGAGAAGCAG CACATCTGGC ACATCCCAGG CCTGTGGCAC 
GGAGCACCTC CCATGGCCGC AGTGAGCTTG GCCTACAGTG AAGCCATATT TGAATTGAAG 
AGATGCCTAC TCGAAAACAT CAGGAACGGC TTGTCGAACC AAAACAAAAA CATCCAGCAG 
CTCATTGAGC TGGTGAGACG GCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001277005.1
CDS	518..3184
Translation	MEGDDCEFRYGDGTNEAQDNDFPTVERSRLQEMLSLLGLETYQVQKLSLQDSLQISFDSMKNWAPQVPKDLPWNFLRKLQALNADARNTTMVLDVLPDARPVEKESQMEEEIIYWDPADDLAADIYSFSELPTPDTPVNPLDLLCALLLSSDSFLQQEIALKMALCQFALPLVLPDSENHYHTFLLWAMRGIVRTWWSQPPRGMGSFREDSVVLSRAPAFAFVRMDVSSNSKSQLLNAVLSPGHRQWDCFWHRDLNLGTNAREISDGLVEISWFFPSGREDLDIFPEPVAFLNLRGDIGSHWLQFKLLTEISSAVFILTDNISKKEYKLLYSMKESTTKYYFILSPYRGKRNTNLRFLNKLIPVLKIDHSHVLVKVSSTDSDSFVKRIRAIVGNVLRAPCRRVSVEDMAHAARKLGLKVDEDCEECQKAKDRMERITRKIKDSDAYRRDELRLQGDPWRKAAQVEKEFCQLQWAVDPPEKHRAELRRRLLELRMQQNGHDPSSGVQEFISGISSPSLSEKQYFLRWMEWGLARVAQPRLRQPPETLLTLRPKHGGTTDVGEPLWPEPLGVEHFLREMGQFYEAESCLVEAGRLPAGQRRFAHFPGLASELLLTGLPLELIDGSTLSMPVRWVTGLLKELHVRLERRSRLVVLSTVGVPGTGKSTLLNTMFGLRFATGKSCGPRGAFMQLITVAEGFSQDLGCDHILVIDSGGLIGGALTSAGDRFELEASLATLLMGLSNVTVISLAETKDIPAAILHAFLRLEKTGHMPNYQFVYQNLHDVSVPGPRPRDKRQLLDPPGDLSRAAAQMEKQGDGFRALAGLAFCDPEKQHIWHIPGLWHGAPPMAAVSLAYSEAIFELKRCLLENIRNGLSNQNKNIQQLIELVRRL

Target ORF information:

RefSeq Version	NM_001290076.1
Organism	Homo sapiens(human)
Definition	Homo sapiens upregulator of cell proliferation (URGCP), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001290076.1

ORF Insert Sequence:

ATGGAAGGAG ATGATTGCGA GTTCCGTTAT GGAGATGGTA CAAATGAGGC TCAGGACAAT 
GATTTTCCAA CAGTGGAGAG AAGCAGGCTT CAAGAAATGC TGTCACTTTT GGGCCTAGAG 
ACGTACCAGG TCCAGAAACT CAGCCTCCAG GACTCTCTGC AGATCAGTTT TGACAGTATG 
AAGAACTGGG CCCCTCAGGT TCCCAAAGAC TTGCCCTGGA ATTTCCTCAG GAAGTTGCAG 
GCCCTCAATG CTGATGCCAG GAATACCACT ATGGTGCTGG ACGTGCTCCC AGACGCCAGG 
CCTGTGGAGA AGGAGAGCCA GATGGAAGAG GAGATCATCT ACTGGGACCC AGCTGATGAC 
CTTGCTGCCG ACATTTATTC CTTTTCTGAG CTGCCCACCC CTGATACGCC AGTGAACCCC 
TTAGACCTTC TCTGTGCCCT GCTGCTCTCC TCAGACAGTT TCCTGCAACA AGAAATAGCG 
TTGAAAATGG CCCTCTGCCA GTTTGCACTC CCACTCGTGT TGCCTGACTC GGAGAACCAC 
TACCATACAT TTCTGCTGTG GGCCATGCGG GGCATTGTGA GGACATGGTG GTCCCAGCCC 
CCAAGGGGCA TGGGGAGCTT CCGGGAAGAC AGCGTGGTCT TGTCCAGGGC GCCCGCCTTC 
GCCTTCGTGC GCATGGACGT CAGTAGCAAC TCCAAGTCCC AGCTTCTCAA CGCCGTCCTC 
AGCCCGGGCC ACAGGCAGTG GGACTGCTTC TGGCATCGGG ACCTCAACTT GGGCACCAAT 
GCCCGGGAGA TTTCGGATGG GTTGGTAGAA ATTTCCTGGT TTTTTCCCAG CGGAAGGGAG 
GACTTGGACA TTTTCCCAGA ACCTGTGGCC TTTCTGAACC TGAGAGGTGA CATCGGGTCT 
CACTGGCTGC AGTTTAAGCT CTTGACAGAA ATCTCCTCCG CTGTGTTTAT ATTGACTGAC 
AATATCAGTA AGAAGGAATA CAAATTGCTG TACTCCATGA AGGAGTCAAC CACAAAATAC 
TACTTCATCC TGAGTCCCTA CCGTGGGAAG CGCAACACAA ACCTGAGATT TCTGAATAAG 
TTAATTCCTG TGCTGAAAAT AGACCACTCA CATGTCCTGG TAAAGGTCAG CAGCACTGAC 
AGCGACAGCT TCGTGAAGAG GATCCGGGCC ATCGTTGGGA ATGTGCTGCG GGCACCCTGC 
AGGCGGGTAT CTGTGGAGGA CATGGCGCAC GCAGCCCGCA AACTGGGCCT AAAGGTCGAC 
GAGGACTGTG AGGAGTGTCA GAAAGCGAAA GACCGGATGG AGAGGATTAC CAGGAAAATC 
AAAGACTCGG ATGCCTACAG AAGGGACGAG CTGAGGCTGC AGGGGGACCC CTGGAGAAAG 
GCAGCCCAAG TGGAGAAGGA GTTCTGCCAG CTCCAGTGGG CCGTGGACCC CCCTGAGAAG 
CACAGGGCTG AGCTGAGGCG GCGGCTGCTA GAACTTCGAA TGCAGCAGAA CGGCCATGAT 
CCCTCCTCGG GGGTGCAGGA GTTCATCTCG GGGATCAGCA GCCCCTCCTT GAGTGAGAAG 
CAGTACTTCC TGAGGTGGAT GGAGTGGGGC CTGGCACGGG TGGCCCAGCC GCGACTGAGA 
CAGCCTCCGG AGACGCTTCT CACCCTGAGA CCAAAGCATG GGGGCACCAC AGACGTGGGG 
GAGCCGCTCT GGCCTGAGCC CCTAGGGGTG GAACACTTCT TGCGGGAGAT GGGACAGTTT 
TATGAGGCTG AGAGCTGTCT TGTGGAGGCA GGGAGGCTGC CGGCAGGCCA GAGGCGTTTT 
GCCCACTTCC CAGGCTTGGC CTCGGAGCTG CTGCTGACAG GGCTGCCTCT GGAGCTAATC 
GATGGGAGCA CGCTGAGCAT GCCCGTCCGC TGGGTCACAG GGCTCCTGAA GGAGCTGCAC 
GTCCGACTGG AGAGACGGTC AAGGCTGGTG GTTCTGTCAA CCGTCGGGGT GCCAGGCACG 
GGCAAGTCCA CACTCCTCAA CACCATGTTT GGGCTGCGGT TTGCCACAGG GAAGAGCTGC 
GGTCCTCGAG GGGCCTTCAT GCAGCTCATC ACAGTGGCTG AGGGCTTCAG CCAGGACCTG 
GGCTGTGACC ACATCCTGGT GATAGACTCC GGGGGCTTGA TAGGTGGGGC CTTGACGTCA 
GCTGGGGACA GATTTGAGCT GGAGGCTTCC TTGGCCACTC TGCTCATGGG ACTGAGCAAT 
GTCACCGTGA TCAGTCTAGC TGAAACCAAG GACATTCCAG CAGCTATTCT GCATGCATTT 
CTGAGGTTAG AAAAAACGGG GCACATGCCC AACTACCAGT TTGTATACCA GAACCTTCAT 
GATGTATCTG TTCCCGGCCC TAGGCCCAGA GACAAGAGAC AGCTCCTGGA TCCACCTGGT 
GACCTGAGCA GGGCTGCAGC CCAGATGGAG AAACAGGGCG ACGGCTTCCG GGCACTGGCA 
GGCCTGGCCT TCTGCGACCC TGAGAAGCAG CACATCTGGC ACATCCCAGG CCTGTGGCAC 
GGAGCACCTC CCATGGCCGC AGTGAGCTTG GCCTACAGTG AAGCCATATT TGAATTGAAG 
AGATGCCTAC TCGAAAACAT CAGGAACGGC TTGTCGAACC AAAACAAAAA CATCCAGCAG 
CTCATTGAGC TGGTGAGACG GCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

URGCP ( NM_001077663.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001071131.1 Homo sapiens upregulator of cell proliferation (URGCP), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu12812
Clone ID Related Accession (Same CDS sequence)	NM_001077663.2
Accession Version	NM_001077663.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2796bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-15
Organism	Homo sapiens(human)
Product	up-regulator of cell proliferation isoform 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA494692.1, AC004985.2, BX648505.1, AB040940.1 and AK000661.1. On Feb 22, 2014 this sequence version replaced NM_001077663.1. Transcript Variant: This variant (3) encodes the longest protein (isoform 3). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.212654.1, SRR1803614.101006.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGTCGC CCGGGATAGA AGTGGAATTA CTGGGCAAAG GGCATTCAGA TTTGGGAGAA 
GTAGCCCCAG AAATAAAAGC ATCAGAGAGA CGAACAGCTG TGGCCATTGC AGATTTGGAA 
TGGAGAGAAA TGGAAGGAGA TGATTGCGAG TTCCGTTATG GAGATGGTAC AAATGAGGCT 
CAGGACAATG ATTTTCCAAC AGTGGAGAGA AGCAGGCTTC AAGAAATGCT GTCACTTTTG 
GGCCTAGAGA CGTACCAGGT CCAGAAACTC AGCCTCCAGG ACTCTCTGCA GATCAGTTTT 
GACAGTATGA AGAACTGGGC CCCTCAGGTT CCCAAAGACT TGCCCTGGAA TTTCCTCAGG 
AAGTTGCAGG CCCTCAATGC TGATGCCAGG AATACCACTA TGGTGCTGGA CGTGCTCCCA 
GACGCCAGGC CTGTGGAGAA GGAGAGCCAG ATGGAAGAGG AGATCATCTA CTGGGACCCA 
GCTGATGACC TTGCTGCCGA CATTTATTCC TTTTCTGAGC TGCCCACCCC TGATACGCCA 
GTGAACCCCT TAGACCTTCT CTGTGCCCTG CTGCTCTCCT CAGACAGTTT CCTGCAACAA 
GAAATAGCGT TGAAAATGGC CCTCTGCCAG TTTGCACTCC CACTCGTGTT GCCTGACTCG 
GAGAACCACT ACCATACATT TCTGCTGTGG GCCATGCGGG GCATTGTGAG GACATGGTGG 
TCCCAGCCCC CAAGGGGCAT GGGGAGCTTC CGGGAAGACA GCGTGGTCTT GTCCAGGGCG 
CCCGCCTTCG CCTTCGTGCG CATGGACGTC AGTAGCAACT CCAAGTCCCA GCTTCTCAAC 
GCCGTCCTCA GCCCGGGCCA CAGGCAGTGG GACTGCTTCT GGCATCGGGA CCTCAACTTG 
GGCACCAATG CCCGGGAGAT TTCGGATGGG TTGGTAGAAA TTTCCTGGTT TTTTCCCAGC 
GGAAGGGAGG ACTTGGACAT TTTCCCAGAA CCTGTGGCCT TTCTGAACCT GAGAGGTGAC 
ATCGGGTCTC ACTGGCTGCA GTTTAAGCTC TTGACAGAAA TCTCCTCCGC TGTGTTTATA 
TTGACTGACA ATATCAGTAA GAAGGAATAC AAATTGCTGT ACTCCATGAA GGAGTCAACC 
ACAAAATACT ACTTCATCCT GAGTCCCTAC CGTGGGAAGC GCAACACAAA CCTGAGATTT 
CTGAATAAGT TAATTCCTGT GCTGAAAATA GACCACTCAC ATGTCCTGGT AAAGGTCAGC 
AGCACTGACA GCGACAGCTT CGTGAAGAGG ATCCGGGCCA TCGTTGGGAA TGTGCTGCGG 
GCACCCTGCA GGCGGGTATC TGTGGAGGAC ATGGCGCACG CAGCCCGCAA ACTGGGCCTA 
AAGGTCGACG AGGACTGTGA GGAGTGTCAG AAAGCGAAAG ACCGGATGGA GAGGATTACC 
AGGAAAATCA AAGACTCGGA TGCCTACAGA AGGGACGAGC TGAGGCTGCA GGGGGACCCC 
TGGAGAAAGG CAGCCCAAGT GGAGAAGGAG TTCTGCCAGC TCCAGTGGGC CGTGGACCCC 
CCTGAGAAGC ACAGGGCTGA GCTGAGGCGG CGGCTGCTAG AACTTCGAAT GCAGCAGAAC 
GGCCATGATC CCTCCTCGGG GGTGCAGGAG TTCATCTCGG GGATCAGCAG CCCCTCCTTG 
AGTGAGAAGC AGTACTTCCT GAGGTGGATG GAGTGGGGCC TGGCACGGGT GGCCCAGCCG 
CGACTGAGAC AGCCTCCGGA GACGCTTCTC ACCCTGAGAC CAAAGCATGG GGGCACCACA 
GACGTGGGGG AGCCGCTCTG GCCTGAGCCC CTAGGGGTGG AACACTTCTT GCGGGAGATG 
GGACAGTTTT ATGAGGCTGA GAGCTGTCTT GTGGAGGCAG GGAGGCTGCC GGCAGGCCAG 
AGGCGTTTTG CCCACTTCCC AGGCTTGGCC TCGGAGCTGC TGCTGACAGG GCTGCCTCTG 
GAGCTAATCG ATGGGAGCAC GCTGAGCATG CCCGTCCGCT GGGTCACAGG GCTCCTGAAG 
GAGCTGCACG TCCGACTGGA GAGACGGTCA AGGCTGGTGG TTCTGTCAAC CGTCGGGGTG 
CCAGGCACGG GCAAGTCCAC ACTCCTCAAC ACCATGTTTG GGCTGCGGTT TGCCACAGGG 
AAGAGCTGCG GTCCTCGAGG GGCCTTCATG CAGCTCATCA CAGTGGCTGA GGGCTTCAGC 
CAGGACCTGG GCTGTGACCA CATCCTGGTG ATAGACTCCG GGGGCTTGAT AGGTGGGGCC 
TTGACGTCAG CTGGGGACAG ATTTGAGCTG GAGGCTTCCT TGGCCACTCT GCTCATGGGA 
CTGAGCAATG TCACCGTGAT CAGTCTAGCT GAAACCAAGG ACATTCCAGC AGCTATTCTG 
CATGCATTTC TGAGGTTAGA AAAAACGGGG CACATGCCCA ACTACCAGTT TGTATACCAG 
AACCTTCATG ATGTATCTGT TCCCGGCCCT AGGCCCAGAG ACAAGAGACA GCTCCTGGAT 
CCACCTGGTG ACCTGAGCAG GGCTGCAGCC CAGATGGAGA AACAGGGCGA CGGCTTCCGG 
GCACTGGCAG GCCTGGCCTT CTGCGACCCT GAGAAGCAGC ACATCTGGCA CATCCCAGGC 
CTGTGGCACG GAGCACCTCC CATGGCCGCA GTGAGCTTGG CCTACAGTGA AGCCATATTT 
GAATTGAAGA GATGCCTACT CGAAAACATC AGGAACGGCT TGTCGAACCA AAACAAAAAC 
ATCCAGCAGC TCATTGAGCT GGTGAGACGG CTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001071131.1
CDS	495..3290
Translation	MASPGIEVELLGKGHSDLGEVAPEIKASERRTAVAIADLEWREMEGDDCEFRYGDGTNEAQDNDFPTVERSRLQEMLSLLGLETYQVQKLSLQDSLQISFDSMKNWAPQVPKDLPWNFLRKLQALNADARNTTMVLDVLPDARPVEKESQMEEEIIYWDPADDLAADIYSFSELPTPDTPVNPLDLLCALLLSSDSFLQQEIALKMALCQFALPLVLPDSENHYHTFLLWAMRGIVRTWWSQPPRGMGSFREDSVVLSRAPAFAFVRMDVSSNSKSQLLNAVLSPGHRQWDCFWHRDLNLGTNAREISDGLVEISWFFPSGREDLDIFPEPVAFLNLRGDIGSHWLQFKLLTEISSAVFILTDNISKKEYKLLYSMKESTTKYYFILSPYRGKRNTNLRFLNKLIPVLKIDHSHVLVKVSSTDSDSFVKRIRAIVGNVLRAPCRRVSVEDMAHAARKLGLKVDEDCEECQKAKDRMERITRKIKDSDAYRRDELRLQGDPWRKAAQVEKEFCQLQWAVDPPEKHRAELRRRLLELRMQQNGHDPSSGVQEFISGISSPSLSEKQYFLRWMEWGLARVAQPRLRQPPETLLTLRPKHGGTTDVGEPLWPEPLGVEHFLREMGQFYEAESCLVEAGRLPAGQRRFAHFPGLASELLLTGLPLELIDGSTLSMPVRWVTGLLKELHVRLERRSRLVVLSTVGVPGTGKSTLLNTMFGLRFATGKSCGPRGAFMQLITVAEGFSQDLGCDHILVIDSGGLIGGALTSAGDRFELEASLATLLMGLSNVTVISLAETKDIPAAILHAFLRLEKTGHMPNYQFVYQNLHDVSVPGPRPRDKRQLLDPPGDLSRAAAQMEKQGDGFRALAGLAFCDPEKQHIWHIPGLWHGAPPMAAVSLAYSEAIFELKRCLLENIRNGLSNQNKNIQQLIELVRRL

Target ORF information:

RefSeq Version	NM_001077663.2
Organism	Homo sapiens(human)
Definition	Homo sapiens upregulator of cell proliferation (URGCP), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001077663.2

ORF Insert Sequence:

ATGGCGTCGC CCGGGATAGA AGTGGAATTA CTGGGCAAAG GGCATTCAGA TTTGGGAGAA 
GTAGCCCCAG AAATAAAAGC ATCAGAGAGA CGAACAGCTG TGGCCATTGC AGATTTGGAA 
TGGAGAGAAA TGGAAGGAGA TGATTGCGAG TTCCGTTATG GAGATGGTAC AAATGAGGCT 
CAGGACAATG ATTTTCCAAC AGTGGAGAGA AGCAGGCTTC AAGAAATGCT GTCACTTTTG 
GGCCTAGAGA CGTACCAGGT CCAGAAACTC AGCCTCCAGG ACTCTCTGCA GATCAGTTTT 
GACAGTATGA AGAACTGGGC CCCTCAGGTT CCCAAAGACT TGCCCTGGAA TTTCCTCAGG 
AAGTTGCAGG CCCTCAATGC TGATGCCAGG AATACCACTA TGGTGCTGGA CGTGCTCCCA 
GACGCCAGGC CTGTGGAGAA GGAGAGCCAG ATGGAAGAGG AGATCATCTA CTGGGACCCA 
GCTGATGACC TTGCTGCCGA CATTTATTCC TTTTCTGAGC TGCCCACCCC TGATACGCCA 
GTGAACCCCT TAGACCTTCT CTGTGCCCTG CTGCTCTCCT CAGACAGTTT CCTGCAACAA 
GAAATAGCGT TGAAAATGGC CCTCTGCCAG TTTGCACTCC CACTCGTGTT GCCTGACTCG 
GAGAACCACT ACCATACATT TCTGCTGTGG GCCATGCGGG GCATTGTGAG GACATGGTGG 
TCCCAGCCCC CAAGGGGCAT GGGGAGCTTC CGGGAAGACA GCGTGGTCTT GTCCAGGGCG 
CCCGCCTTCG CCTTCGTGCG CATGGACGTC AGTAGCAACT CCAAGTCCCA GCTTCTCAAC 
GCCGTCCTCA GCCCGGGCCA CAGGCAGTGG GACTGCTTCT GGCATCGGGA CCTCAACTTG 
GGCACCAATG CCCGGGAGAT TTCGGATGGG TTGGTAGAAA TTTCCTGGTT TTTTCCCAGC 
GGAAGGGAGG ACTTGGACAT TTTCCCAGAA CCTGTGGCCT TTCTGAACCT GAGAGGTGAC 
ATCGGGTCTC ACTGGCTGCA GTTTAAGCTC TTGACAGAAA TCTCCTCCGC TGTGTTTATA 
TTGACTGACA ATATCAGTAA GAAGGAATAC AAATTGCTGT ACTCCATGAA GGAGTCAACC 
ACAAAATACT ACTTCATCCT GAGTCCCTAC CGTGGGAAGC GCAACACAAA CCTGAGATTT 
CTGAATAAGT TAATTCCTGT GCTGAAAATA GACCACTCAC ATGTCCTGGT AAAGGTCAGC 
AGCACTGACA GCGACAGCTT CGTGAAGAGG ATCCGGGCCA TCGTTGGGAA TGTGCTGCGG 
GCACCCTGCA GGCGGGTATC TGTGGAGGAC ATGGCGCACG CAGCCCGCAA ACTGGGCCTA 
AAGGTCGACG AGGACTGTGA GGAGTGTCAG AAAGCGAAAG ACCGGATGGA GAGGATTACC 
AGGAAAATCA AAGACTCGGA TGCCTACAGA AGGGACGAGC TGAGGCTGCA GGGGGACCCC 
TGGAGAAAGG CAGCCCAAGT GGAGAAGGAG TTCTGCCAGC TCCAGTGGGC CGTGGACCCC 
CCTGAGAAGC ACAGGGCTGA GCTGAGGCGG CGGCTGCTAG AACTTCGAAT GCAGCAGAAC 
GGCCATGATC CCTCCTCGGG GGTGCAGGAG TTCATCTCGG GGATCAGCAG CCCCTCCTTG 
AGTGAGAAGC AGTACTTCCT GAGGTGGATG GAGTGGGGCC TGGCACGGGT GGCCCAGCCG 
CGACTGAGAC AGCCTCCGGA GACGCTTCTC ACCCTGAGAC CAAAGCATGG GGGCACCACA 
GACGTGGGGG AGCCGCTCTG GCCTGAGCCC CTAGGGGTGG AACACTTCTT GCGGGAGATG 
GGACAGTTTT ATGAGGCTGA GAGCTGTCTT GTGGAGGCAG GGAGGCTGCC GGCAGGCCAG 
AGGCGTTTTG CCCACTTCCC AGGCTTGGCC TCGGAGCTGC TGCTGACAGG GCTGCCTCTG 
GAGCTAATCG ATGGGAGCAC GCTGAGCATG CCCGTCCGCT GGGTCACAGG GCTCCTGAAG 
GAGCTGCACG TCCGACTGGA GAGACGGTCA AGGCTGGTGG TTCTGTCAAC CGTCGGGGTG 
CCAGGCACGG GCAAGTCCAC ACTCCTCAAC ACCATGTTTG GGCTGCGGTT TGCCACAGGG 
AAGAGCTGCG GTCCTCGAGG GGCCTTCATG CAGCTCATCA CAGTGGCTGA GGGCTTCAGC 
CAGGACCTGG GCTGTGACCA CATCCTGGTG ATAGACTCCG GGGGCTTGAT AGGTGGGGCC 
TTGACGTCAG CTGGGGACAG ATTTGAGCTG GAGGCTTCCT TGGCCACTCT GCTCATGGGA 
CTGAGCAATG TCACCGTGAT CAGTCTAGCT GAAACCAAGG ACATTCCAGC AGCTATTCTG 
CATGCATTTC TGAGGTTAGA AAAAACGGGG CACATGCCCA ACTACCAGTT TGTATACCAG 
AACCTTCATG ATGTATCTGT TCCCGGCCCT AGGCCCAGAG ACAAGAGACA GCTCCTGGAT 
CCACCTGGTG ACCTGAGCAG GGCTGCAGCC CAGATGGAGA AACAGGGCGA CGGCTTCCGG 
GCACTGGCAG GCCTGGCCTT CTGCGACCCT GAGAAGCAGC ACATCTGGCA CATCCCAGGC 
CTGTGGCACG GAGCACCTCC CATGGCCGCA GTGAGCTTGG CCTACAGTGA AGCCATATTT 
GAATTGAAGA GATGCCTACT CGAAAACATC AGGAACGGCT TGTCGAACCA AAACAAAAAC 
ATCCAGCAGC TCATTGAGCT GGTGAGACGG CTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

URGCP ( NM_017920.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_060390.3 Homo sapiens upregulator of cell proliferation (URGCP), transcript variant 1, mRNA.

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CloneID	OHu12930
Clone ID Related Accession (Same CDS sequence)	NM_017920.4
Accession Version	NM_017920.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2769bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-15
Organism	Homo sapiens(human)
Product	up-regulator of cell proliferation isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA494692.1, AC004985.2, AK314339.1, AB040940.1 and AK000661.1. On Feb 22, 2014 this sequence version replaced NM_017920.3. Transcript Variant: This variant (1) lacks an alternate in-frame exon in the 5' coding region, compared to variant 3. The resulting protein (isoform 1) is shorter, compared to isoform 3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.111956.1, SRR1803611.186235.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGTCGC CCGGGCATTC AGATTTGGGA GAAGTAGCCC CAGAAATAAA AGCATCAGAG 
AGACGAACAG CTGTGGCCAT TGCAGATTTG GAATGGAGAG AAATGGAAGG AGATGATTGC 
GAGTTCCGTT ATGGAGATGG TACAAATGAG GCTCAGGACA ATGATTTTCC AACAGTGGAG 
AGAAGCAGGC TTCAAGAAAT GCTGTCACTT TTGGGCCTAG AGACGTACCA GGTCCAGAAA 
CTCAGCCTCC AGGACTCTCT GCAGATCAGT TTTGACAGTA TGAAGAACTG GGCCCCTCAG 
GTTCCCAAAG ACTTGCCCTG GAATTTCCTC AGGAAGTTGC AGGCCCTCAA TGCTGATGCC 
AGGAATACCA CTATGGTGCT GGACGTGCTC CCAGACGCCA GGCCTGTGGA GAAGGAGAGC 
CAGATGGAAG AGGAGATCAT CTACTGGGAC CCAGCTGATG ACCTTGCTGC CGACATTTAT 
TCCTTTTCTG AGCTGCCCAC CCCTGATACG CCAGTGAACC CCTTAGACCT TCTCTGTGCC 
CTGCTGCTCT CCTCAGACAG TTTCCTGCAA CAAGAAATAG CGTTGAAAAT GGCCCTCTGC 
CAGTTTGCAC TCCCACTCGT GTTGCCTGAC TCGGAGAACC ACTACCATAC ATTTCTGCTG 
TGGGCCATGC GGGGCATTGT GAGGACATGG TGGTCCCAGC CCCCAAGGGG CATGGGGAGC 
TTCCGGGAAG ACAGCGTGGT CTTGTCCAGG GCGCCCGCCT TCGCCTTCGT GCGCATGGAC 
GTCAGTAGCA ACTCCAAGTC CCAGCTTCTC AACGCCGTCC TCAGCCCGGG CCACAGGCAG 
TGGGACTGCT TCTGGCATCG GGACCTCAAC TTGGGCACCA ATGCCCGGGA GATTTCGGAT 
GGGTTGGTAG AAATTTCCTG GTTTTTTCCC AGCGGAAGGG AGGACTTGGA CATTTTCCCA 
GAACCTGTGG CCTTTCTGAA CCTGAGAGGT GACATCGGGT CTCACTGGCT GCAGTTTAAG 
CTCTTGACAG AAATCTCCTC CGCTGTGTTT ATATTGACTG ACAATATCAG TAAGAAGGAA 
TACAAATTGC TGTACTCCAT GAAGGAGTCA ACCACAAAAT ACTACTTCAT CCTGAGTCCC 
TACCGTGGGA AGCGCAACAC AAACCTGAGA TTTCTGAATA AGTTAATTCC TGTGCTGAAA 
ATAGACCACT CACATGTCCT GGTAAAGGTC AGCAGCACTG ACAGCGACAG CTTCGTGAAG 
AGGATCCGGG CCATCGTTGG GAATGTGCTG CGGGCACCCT GCAGGCGGGT ATCTGTGGAG 
GACATGGCGC ACGCAGCCCG CAAACTGGGC CTAAAGGTCG ACGAGGACTG TGAGGAGTGT 
CAGAAAGCGA AAGACCGGAT GGAGAGGATT ACCAGGAAAA TCAAAGACTC GGATGCCTAC 
AGAAGGGACG AGCTGAGGCT GCAGGGGGAC CCCTGGAGAA AGGCAGCCCA AGTGGAGAAG 
GAGTTCTGCC AGCTCCAGTG GGCCGTGGAC CCCCCTGAGA AGCACAGGGC TGAGCTGAGG 
CGGCGGCTGC TAGAACTTCG AATGCAGCAG AACGGCCATG ATCCCTCCTC GGGGGTGCAG 
GAGTTCATCT CGGGGATCAG CAGCCCCTCC TTGAGTGAGA AGCAGTACTT CCTGAGGTGG 
ATGGAGTGGG GCCTGGCACG GGTGGCCCAG CCGCGACTGA GACAGCCTCC GGAGACGCTT 
CTCACCCTGA GACCAAAGCA TGGGGGCACC ACAGACGTGG GGGAGCCGCT CTGGCCTGAG 
CCCCTAGGGG TGGAACACTT CTTGCGGGAG ATGGGACAGT TTTATGAGGC TGAGAGCTGT 
CTTGTGGAGG CAGGGAGGCT GCCGGCAGGC CAGAGGCGTT TTGCCCACTT CCCAGGCTTG 
GCCTCGGAGC TGCTGCTGAC AGGGCTGCCT CTGGAGCTAA TCGATGGGAG CACGCTGAGC 
ATGCCCGTCC GCTGGGTCAC AGGGCTCCTG AAGGAGCTGC ACGTCCGACT GGAGAGACGG 
TCAAGGCTGG TGGTTCTGTC AACCGTCGGG GTGCCAGGCA CGGGCAAGTC CACACTCCTC 
AACACCATGT TTGGGCTGCG GTTTGCCACA GGGAAGAGCT GCGGTCCTCG AGGGGCCTTC 
ATGCAGCTCA TCACAGTGGC TGAGGGCTTC AGCCAGGACC TGGGCTGTGA CCACATCCTG 
GTGATAGACT CCGGGGGCTT GATAGGTGGG GCCTTGACGT CAGCTGGGGA CAGATTTGAG 
CTGGAGGCTT CCTTGGCCAC TCTGCTCATG GGACTGAGCA ATGTCACCGT GATCAGTCTA 
GCTGAAACCA AGGACATTCC AGCAGCTATT CTGCATGCAT TTCTGAGGTT AGAAAAAACG 
GGGCACATGC CCAACTACCA GTTTGTATAC CAGAACCTTC ATGATGTATC TGTTCCCGGC 
CCTAGGCCCA GAGACAAGAG ACAGCTCCTG GATCCACCTG GTGACCTGAG CAGGGCTGCA 
GCCCAGATGG AGAAACAGGG CGACGGCTTC CGGGCACTGG CAGGCCTGGC CTTCTGCGAC 
CCTGAGAAGC AGCACATCTG GCACATCCCA GGCCTGTGGC ACGGAGCACC TCCCATGGCC 
GCAGTGAGCT TGGCCTACAG TGAAGCCATA TTTGAATTGA AGAGATGCCT ACTCGAAAAC 
ATCAGGAACG GCTTGTCGAA CCAAAACAAA AACATCCAGC AGCTCATTGA GCTGGTGAGA 
CGGCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060390.3
CDS	495..3263
Translation	MASPGHSDLGEVAPEIKASERRTAVAIADLEWREMEGDDCEFRYGDGTNEAQDNDFPTVERSRLQEMLSLLGLETYQVQKLSLQDSLQISFDSMKNWAPQVPKDLPWNFLRKLQALNADARNTTMVLDVLPDARPVEKESQMEEEIIYWDPADDLAADIYSFSELPTPDTPVNPLDLLCALLLSSDSFLQQEIALKMALCQFALPLVLPDSENHYHTFLLWAMRGIVRTWWSQPPRGMGSFREDSVVLSRAPAFAFVRMDVSSNSKSQLLNAVLSPGHRQWDCFWHRDLNLGTNAREISDGLVEISWFFPSGREDLDIFPEPVAFLNLRGDIGSHWLQFKLLTEISSAVFILTDNISKKEYKLLYSMKESTTKYYFILSPYRGKRNTNLRFLNKLIPVLKIDHSHVLVKVSSTDSDSFVKRIRAIVGNVLRAPCRRVSVEDMAHAARKLGLKVDEDCEECQKAKDRMERITRKIKDSDAYRRDELRLQGDPWRKAAQVEKEFCQLQWAVDPPEKHRAELRRRLLELRMQQNGHDPSSGVQEFISGISSPSLSEKQYFLRWMEWGLARVAQPRLRQPPETLLTLRPKHGGTTDVGEPLWPEPLGVEHFLREMGQFYEAESCLVEAGRLPAGQRRFAHFPGLASELLLTGLPLELIDGSTLSMPVRWVTGLLKELHVRLERRSRLVVLSTVGVPGTGKSTLLNTMFGLRFATGKSCGPRGAFMQLITVAEGFSQDLGCDHILVIDSGGLIGGALTSAGDRFELEASLATLLMGLSNVTVISLAETKDIPAAILHAFLRLEKTGHMPNYQFVYQNLHDVSVPGPRPRDKRQLLDPPGDLSRAAAQMEKQGDGFRALAGLAFCDPEKQHIWHIPGLWHGAPPMAAVSLAYSEAIFELKRCLLENIRNGLSNQNKNIQQLIELVRRL

Target ORF information:

RefSeq Version	NM_017920.4
Organism	Homo sapiens(human)
Definition	Homo sapiens upregulator of cell proliferation (URGCP), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_017920.4

ORF Insert Sequence:

ATGGCGTCGC CCGGGCATTC AGATTTGGGA GAAGTAGCCC CAGAAATAAA AGCATCAGAG 
AGACGAACAG CTGTGGCCAT TGCAGATTTG GAATGGAGAG AAATGGAAGG AGATGATTGC 
GAGTTCCGTT ATGGAGATGG TACAAATGAG GCTCAGGACA ATGATTTTCC AACAGTGGAG 
AGAAGCAGGC TTCAAGAAAT GCTGTCACTT TTGGGCCTAG AGACGTACCA GGTCCAGAAA 
CTCAGCCTCC AGGACTCTCT GCAGATCAGT TTTGACAGTA TGAAGAACTG GGCCCCTCAG 
GTTCCCAAAG ACTTGCCCTG GAATTTCCTC AGGAAGTTGC AGGCCCTCAA TGCTGATGCC 
AGGAATACCA CTATGGTGCT GGACGTGCTC CCAGACGCCA GGCCTGTGGA GAAGGAGAGC 
CAGATGGAAG AGGAGATCAT CTACTGGGAC CCAGCTGATG ACCTTGCTGC CGACATTTAT 
TCCTTTTCTG AGCTGCCCAC CCCTGATACG CCAGTGAACC CCTTAGACCT TCTCTGTGCC 
CTGCTGCTCT CCTCAGACAG TTTCCTGCAA CAAGAAATAG CGTTGAAAAT GGCCCTCTGC 
CAGTTTGCAC TCCCACTCGT GTTGCCTGAC TCGGAGAACC ACTACCATAC ATTTCTGCTG 
TGGGCCATGC GGGGCATTGT GAGGACATGG TGGTCCCAGC CCCCAAGGGG CATGGGGAGC 
TTCCGGGAAG ACAGCGTGGT CTTGTCCAGG GCGCCCGCCT TCGCCTTCGT GCGCATGGAC 
GTCAGTAGCA ACTCCAAGTC CCAGCTTCTC AACGCCGTCC TCAGCCCGGG CCACAGGCAG 
TGGGACTGCT TCTGGCATCG GGACCTCAAC TTGGGCACCA ATGCCCGGGA GATTTCGGAT 
GGGTTGGTAG AAATTTCCTG GTTTTTTCCC AGCGGAAGGG AGGACTTGGA CATTTTCCCA 
GAACCTGTGG CCTTTCTGAA CCTGAGAGGT GACATCGGGT CTCACTGGCT GCAGTTTAAG 
CTCTTGACAG AAATCTCCTC CGCTGTGTTT ATATTGACTG ACAATATCAG TAAGAAGGAA 
TACAAATTGC TGTACTCCAT GAAGGAGTCA ACCACAAAAT ACTACTTCAT CCTGAGTCCC 
TACCGTGGGA AGCGCAACAC AAACCTGAGA TTTCTGAATA AGTTAATTCC TGTGCTGAAA 
ATAGACCACT CACATGTCCT GGTAAAGGTC AGCAGCACTG ACAGCGACAG CTTCGTGAAG 
AGGATCCGGG CCATCGTTGG GAATGTGCTG CGGGCACCCT GCAGGCGGGT ATCTGTGGAG 
GACATGGCGC ACGCAGCCCG CAAACTGGGC CTAAAGGTCG ACGAGGACTG TGAGGAGTGT 
CAGAAAGCGA AAGACCGGAT GGAGAGGATT ACCAGGAAAA TCAAAGACTC GGATGCCTAC 
AGAAGGGACG AGCTGAGGCT GCAGGGGGAC CCCTGGAGAA AGGCAGCCCA AGTGGAGAAG 
GAGTTCTGCC AGCTCCAGTG GGCCGTGGAC CCCCCTGAGA AGCACAGGGC TGAGCTGAGG 
CGGCGGCTGC TAGAACTTCG AATGCAGCAG AACGGCCATG ATCCCTCCTC GGGGGTGCAG 
GAGTTCATCT CGGGGATCAG CAGCCCCTCC TTGAGTGAGA AGCAGTACTT CCTGAGGTGG 
ATGGAGTGGG GCCTGGCACG GGTGGCCCAG CCGCGACTGA GACAGCCTCC GGAGACGCTT 
CTCACCCTGA GACCAAAGCA TGGGGGCACC ACAGACGTGG GGGAGCCGCT CTGGCCTGAG 
CCCCTAGGGG TGGAACACTT CTTGCGGGAG ATGGGACAGT TTTATGAGGC TGAGAGCTGT 
CTTGTGGAGG CAGGGAGGCT GCCGGCAGGC CAGAGGCGTT TTGCCCACTT CCCAGGCTTG 
GCCTCGGAGC TGCTGCTGAC AGGGCTGCCT CTGGAGCTAA TCGATGGGAG CACGCTGAGC 
ATGCCCGTCC GCTGGGTCAC AGGGCTCCTG AAGGAGCTGC ACGTCCGACT GGAGAGACGG 
TCAAGGCTGG TGGTTCTGTC AACCGTCGGG GTGCCAGGCA CGGGCAAGTC CACACTCCTC 
AACACCATGT TTGGGCTGCG GTTTGCCACA GGGAAGAGCT GCGGTCCTCG AGGGGCCTTC 
ATGCAGCTCA TCACAGTGGC TGAGGGCTTC AGCCAGGACC TGGGCTGTGA CCACATCCTG 
GTGATAGACT CCGGGGGCTT GATAGGTGGG GCCTTGACGT CAGCTGGGGA CAGATTTGAG 
CTGGAGGCTT CCTTGGCCAC TCTGCTCATG GGACTGAGCA ATGTCACCGT GATCAGTCTA 
GCTGAAACCA AGGACATTCC AGCAGCTATT CTGCATGCAT TTCTGAGGTT AGAAAAAACG 
GGGCACATGC CCAACTACCA GTTTGTATAC CAGAACCTTC ATGATGTATC TGTTCCCGGC 
CCTAGGCCCA GAGACAAGAG ACAGCTCCTG GATCCACCTG GTGACCTGAG CAGGGCTGCA 
GCCCAGATGG AGAAACAGGG CGACGGCTTC CGGGCACTGG CAGGCCTGGC CTTCTGCGAC 
CCTGAGAAGC AGCACATCTG GCACATCCCA GGCCTGTGGC ACGGAGCACC TCCCATGGCC 
GCAGTGAGCT TGGCCTACAG TGAAGCCATA TTTGAATTGA AGAGATGCCT ACTCGAAAAC 
ATCAGGAACG GCTTGTCGAA CCAAAACAAA AACATCCAGC AGCTCATTGA GCTGGTGAGA 
CGGCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Downregulation of miR-16 via URGCP pathway contributes to glioma growth.
Scientific reports7(1)13470(2017 Oct)
Hong L,Qing O,Ji Z,Chengqu Z,Ying C,Hao C,Minhui X,Lunshan X

miR-519 suppresses nasopharyngeal carcinoma cell proliferation by targeting oncogene URG4/URGCP.
Life sciences17547-51(2017 Apr)
Yu G,Zhang T,Jing Y,Bao Q,Tang Q,Zhang Y

SP1 is a transcriptional regulator of URG-4/URGCP gene in hepatocytes.
Molecular and cellular biochemistry423(1-2)75-83(2016 Dec)
Tokay E,Kockar F

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URGCP cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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