INTS8 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	INTS8
Entrez Gene ID	55656
Full Name	integrator complex subunit 8
Synonyms	C8orf52,INT8
General protein information	Preferred Names integrator complex subunit 8 Names integrator complex subunit 8 protein kaonashi-1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 8 Map Location: 8q22.1
Summary	This gene encodes a subunit of the Integrator complex which is involved in the cleavage of small nuclear RNAs U1 and U2 within the nucleus. The encoded protein associates with RNA polymerase II and is recruited to the U1 and U2 small nuclear RNA genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012].
Disorder MIM:	611351

mRNA and Protein(s)

mRNA	Protein	Name
NM_017864.4	NP_060334.2	integrator complex subunit 8
XM_017013617.1	XP_016869106.1	integrator complex subunit 8 isoform X2
XM_017013618.1	XP_016869107.1	integrator complex subunit 8 isoform X3
NM_017864.3	NP_060334.2	integrator complex subunit 8
XM_017013616.1	XP_016869105.1	integrator complex subunit 8 isoform X1
XM_017013619.1	XP_016869108.1	integrator complex subunit 8 isoform X4

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	INTS8	XP_519863.4
Mus musculus (house mouse)	Ints8	NP_001153067.1
Gallus gallus (chicken)	INTS8	NP_001035318.1
Danio rerio (zebrafish)	ints8	NP_001018592.2
Drosophila melanogaster (fruit fly)	IntS8	NP_611162.2
Homo sapiens (human)	INTS8	NP_060334.2
Xenopus tropicalis (tropical clawed frog)	ints8	NP_001090873.1
	INTS8	XP_001089895.1
Canis lupus familiaris (dog)	INTS8	XP_544184.3
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP011449	XP_317854.4
Bos taurus (cattle)	INTS8	XP_005215746.1

Gene Ontology
Bibliography

Related articles in PubMed

Human mutations in integrator complex subunits link transcriptome integrity to brain development.
Oegema R, Baillat D, Schot R, van Unen LM, Brooks A, Kia SK, Hoogeboom AJM, Xia Z, Li W, Cesaroni M, Lequin MH, van Slegtenhorst M, Dobyns WB, de Coo IFM, Verheijen FW, Kremer A, van der Spek PJ, Heijsman D, Wagner EJ, Fornerod M, Mancini GMS
PLoS genetics13(5)e1006809(2017 May)

Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes.
Ng MC, Shriner D, Chen BH, Li J, Chen WM, Guo X, Liu J, Bielinski SJ, Yanek LR, Nalls MA, Comeau ME, Rasmussen-Torvik LJ, Jensen RA, Evans DS, Sun YV, An P, Patel SR, Lu Y, Long J, Armstrong LL, Wagenknecht L, Yang L, Snively BM, Palmer ND, Mudgal P, Langefeld CD, Keene KL, Freedman BI, Mychaleckyj JC, Nayak U, Raffel LJ, Goodarzi MO, Chen YD, Taylor HA Jr, Correa A, Sims M, Couper D, Pankow JS, Boerwinkle E, Adeyemo A, Doumatey A, Chen G, Mathias RA, Vaidya D, Singleton AB, Zonderman AB, Igo RP Jr, Sedor JR, , Kabagambe EK, Siscovick DS, McKnight B, Rice K, Liu Y, Hsueh WC, Zhao W, Bielak LF, Kraja A, Province MA, Bottinger EP, Gottesman O, Cai Q, Zheng W, Blot WJ, Lowe WL, Pacheco JA, Crawford DC, , , Grundberg E, , Rich SS, Hayes MG, Shu XO, Loos RJ, Borecki IB, Peyser PA, Cummings SR, Psaty BM, Fornage M, Iyengar SK, Evans MK, Becker DM, Kao WH, Wilson JG, Rotter JI, Sale MM, Liu S, Rotimi CN, Bowden DW,
PLoS genetics10(8)e1004517(2014 Aug)

Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II.
Baillat D, Hakimi MA, N??r AM, Shilatifard A, Cooch N, Shiekhattar R
Cell123(2)265-76(2005 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Mutations INTS8 cause a severe neurodevelopmental syndrome. INTS8 mutations lead in vitro to instability of the complex and impaired function.
Title: Human mutations in integrator complex subunits link transcriptome integrity to brain development.

Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.

The following INTS8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the INTS8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu98097	XM_017013619.1 Latest version!	Homo sapiens integrator complex subunit 8 (INTS8), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	10-12	$307.30 $439.00
OHu00549	NM_017864.4 Latest version!	Homo sapiens integrator complex subunit 8 (INTS8), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$265.30 $379.00
OHu98094	XM_017013616.1 Latest version!	Homo sapiens integrator complex subunit 8 (INTS8), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
OHu98095	XM_017013617.1 Latest version!	Homo sapiens integrator complex subunit 8 (INTS8), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
OHu98096	XM_017013618.1 Latest version!	Homo sapiens integrator complex subunit 8 (INTS8), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
View Old Accession Versions >>
OHu00549	NM_017864.3	Homo sapiens integrator complex subunit 8 (INTS8), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$265.30 $379.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

INTS8 ( XM_017013619.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016869108.1 Homo sapiens integrator complex subunit 8 (INTS8), transcript variant X5, mRNA.

Price & Availability↑

CloneID	OHu98097
Clone ID Related Accession (Same CDS sequence)	XM_017013619.1
Accession Version	XM_017013619.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1674bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	integrator complex subunit 8 isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGCTT TTCTAAAGAA TGTGTGTCTG GGGTTGGAAG ATCTGCAGTA TGTTTTCATG 
ATTTCTTCAC ATGAGCTTTT CATTACATTG TTGAAAGATG AAGAACGAAA GCTACTTGTT 
GATCAGATGA GGAAGAGATC CCCTAGAGTA AATCTGTGCA TTAAACCTGT AACTTCATTT 
TATGATATCC CAGCTTCAGC AAGTGTCAAC ATTGGTCAGT TAGAGCATCA ACTTATATTG 
TCAGTGGATC CTTGGAGGAT TAGACAAATT TTAATTGAAT TACATGGTAT GACTTCAGAG 
CGCCAGTTCT GGACAGTGTC TAATAAGTGG GAAGTACCTT CTGTCTATAG TGGTGTTATC 
CTGGGAATTA AAGACAATTT AACAAGAGAT TTGGTTTATA TTCTTATGGC CAAAGGTTTG 
CACTGCAGTA CTGTTAAGGA CTTTTCCCAT GCTAAACAGC TCTTTGCTGC TTGTTTGGAG 
TTGGTAACAG AGTTCTCACC GAAGCTTCGT CAGGTCATGC TGAATGAGAT GTTGCTTTTG 
GATATTCATA CACACGAAGC TGGGACAGGG CAGGCAGGAG AGAGACCGCC ATCCGACCTT 
ATAAGTAGAG TACGAGGCTA TCTGGAAATG AGGCTTCCTG ATATTCCTCT TCGTCAAGTT 
ATAGCTGAGG AATGTGTTGC CTTTATGTTA AACTGGAGAG AAAATGAATA CCTTACACTC 
CAAGTTCCTG CATTTTTGCT TCAGAGTAAT CCATATGTAA AGCTTGGACA GCTTTTAGCA 
GCTACATGCA AAGAACTTCC AGGCCCTAAA GAAAGTAGAC GGACTGCCAA AGACCTTTGG 
GAAGTTGTTG TTCAAATCTG TAGTGTGTCC AGTCAGCACA AACGAGGAAA TGATGGCAGA 
GTTAGTTTAA TAAAACAGAG GGAATCTACG TTAGGTATCA TGTATCGGAG TGAACTGCTT 
TCTTTTATCA AAAAATTACG AGAACCACTC GTTTTGACTA TTATTTTATC ACTCTTTGTG 
AAACTTCACA ATGTTCGGGA GGACATTGTG AATGATATTA CAGCTGAACA CATTTCTATT 
TGGCCATCTT CCATTCCCAA CCTCCAGTCT GTGGACTTTG AAGCTGTGGC AATCACAGTG 
AAAGAGCTAG TTCGATATAC ACTCAGTATA AATCCAAATA ACCATTCTTG GTTAATTATC 
CAGGCAGATA TTTACTTTGC AACGAATCAG TATTCAGCAG CTCTTCACTA TTACCTCCAG 
GCAGGAGCTG TGTGTTCTGA CTTCTTTAAC AAGGCTGTGC CCCCTGATGT TTATACAGAC 
CAGGTAATAA AACGAATGAT AAAATGTTGT TCTTTGCTGA ATTGCCACAC ACAGGTGGCC 
ATTTTATGTC AGTTCCTCAG AGAAATTGAC TACAAAACAG CGTTTAAATC TCTGCAAGAA 
CAAAACAGTC ATGATGCTAT GGACTCCTAC TACGACTACA TATGGGATGT TACCATTTTG 
GAATACTTGA CTTATCTTCA TCATAAAAGA GGAGAAACAG ATAAAAGACA AATTGCAATC 
AAAGCCATCG GCCAGACAGA GTTGAATGCA AGCAATCCAG AAGAAGTGTT ACAGCTGGCA 
GCGCAGAGAA GGAAAAAAAA GTTTCTCCAA GCAATGGCAA AACTTTACTT TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016869108.1
CDS	1416..3089
Translation	MAAFLKNVCLGLEDLQYVFMISSHELFITLLKDEERKLLVDQMRKRSPRVNLCIKPVTSFYDIPASASVNIGQLEHQLILSVDPWRIRQILIELHGMTSERQFWTVSNKWEVPSVYSGVILGIKDNLTRDLVYILMAKGLHCSTVKDFSHAKQLFAACLELVTEFSPKLRQVMLNEMLLLDIHTHEAGTGQAGERPPSDLISRVRGYLEMRLPDIPLRQVIAEECVAFMLNWRENEYLTLQVPAFLLQSNPYVKLGQLLAATCKELPGPKESRRTAKDLWEVVVQICSVSSQHKRGNDGRVSLIKQRESTLGIMYRSELLSFIKKLREPLVLTIILSLFVKLHNVREDIVNDITAEHISIWPSSIPNLQSVDFEAVAITVKELVRYTLSINPNNHSWLIIQADIYFATNQYSAALHYYLQAGAVCSDFFNKAVPPDVYTDQVIKRMIKCCSLLNCHTQVAILCQFLREIDYKTAFKSLQEQNSHDAMDSYYDYIWDVTILEYLTYLHHKRGETDKRQIAIKAIGQTELNASNPEEVLQLAAQRRKKKFLQAMAKLYF

Target ORF information:

RefSeq Version	XM_017013619.1
Organism	Homo sapiens(human)
Definition	Homo sapiens integrator complex subunit 8 (INTS8), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017013619.1

ORF Insert Sequence:

ATGGCTGCTT TTCTAAAGAA TGTGTGTCTG GGGTTGGAAG ATCTGCAGTA TGTTTTCATG 
ATTTCTTCAC ATGAGCTTTT CATTACATTG TTGAAAGATG AAGAACGAAA GCTACTTGTT 
GATCAGATGA GGAAGAGATC CCCTAGAGTA AATCTGTGCA TTAAACCTGT AACTTCATTT 
TATGATATCC CAGCTTCAGC AAGTGTCAAC ATTGGTCAGT TAGAGCATCA ACTTATATTG 
TCAGTGGATC CTTGGAGGAT TAGACAAATT TTAATTGAAT TACATGGTAT GACTTCAGAG 
CGCCAGTTCT GGACAGTGTC TAATAAGTGG GAAGTACCTT CTGTCTATAG TGGTGTTATC 
CTGGGAATTA AAGACAATTT AACAAGAGAT TTGGTTTATA TTCTTATGGC CAAAGGTTTG 
CACTGCAGTA CTGTTAAGGA CTTTTCCCAT GCTAAACAGC TCTTTGCTGC TTGTTTGGAG 
TTGGTAACAG AGTTCTCACC GAAGCTTCGT CAGGTCATGC TGAATGAGAT GTTGCTTTTG 
GATATTCATA CACACGAAGC TGGGACAGGG CAGGCAGGAG AGAGACCGCC ATCCGACCTT 
ATAAGTAGAG TACGAGGCTA TCTGGAAATG AGGCTTCCTG ATATTCCTCT TCGTCAAGTT 
ATAGCTGAGG AATGTGTTGC CTTTATGTTA AACTGGAGAG AAAATGAATA CCTTACACTC 
CAAGTTCCTG CATTTTTGCT TCAGAGTAAT CCATATGTAA AGCTTGGACA GCTTTTAGCA 
GCTACATGCA AAGAACTTCC AGGCCCTAAA GAAAGTAGAC GGACTGCCAA AGACCTTTGG 
GAAGTTGTTG TTCAAATCTG TAGTGTGTCC AGTCAGCACA AACGAGGAAA TGATGGCAGA 
GTTAGTTTAA TAAAACAGAG GGAATCTACG TTAGGTATCA TGTATCGGAG TGAACTGCTT 
TCTTTTATCA AAAAATTACG AGAACCACTC GTTTTGACTA TTATTTTATC ACTCTTTGTG 
AAACTTCACA ATGTTCGGGA GGACATTGTG AATGATATTA CAGCTGAACA CATTTCTATT 
TGGCCATCTT CCATTCCCAA CCTCCAGTCT GTGGACTTTG AAGCTGTGGC AATCACAGTG 
AAAGAGCTAG TTCGATATAC ACTCAGTATA AATCCAAATA ACCATTCTTG GTTAATTATC 
CAGGCAGATA TTTACTTTGC AACGAATCAG TATTCAGCAG CTCTTCACTA TTACCTCCAG 
GCAGGAGCTG TGTGTTCTGA CTTCTTTAAC AAGGCTGTGC CCCCTGATGT TTATACAGAC 
CAGGTAATAA AACGAATGAT AAAATGTTGT TCTTTGCTGA ATTGCCACAC ACAGGTGGCC 
ATTTTATGTC AGTTCCTCAG AGAAATTGAC TACAAAACAG CGTTTAAATC TCTGCAAGAA 
CAAAACAGTC ATGATGCTAT GGACTCCTAC TACGACTACA TATGGGATGT TACCATTTTG 
GAATACTTGA CTTATCTTCA TCATAAAAGA GGAGAAACAG ATAAAAGACA AATTGCAATC 
AAAGCCATCG GCCAGACAGA GTTGAATGCA AGCAATCCAG AAGAAGTGTT ACAGCTGGCA 
GCGCAGAGAA GGAAAAAAAA GTTTCTCCAA GCAATGGCAA AACTTTACTT TTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

INTS8 ( NM_017864.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_060334.2 Homo sapiens integrator complex subunit 8 (INTS8), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu00549
Clone ID Related Accession (Same CDS sequence)	NM_017864.4 , NM_017864.3
Accession Version	NM_017864.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2988bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-25
Organism	Homo sapiens(human)
Product	integrator complex subunit 8
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AP003692.2, DA644524.1, AB161944.1 and BC136754.1. This sequence is a reference standard in the RefSeqGene project. On May 17, 2019 this sequence version replaced NM_017864.3. Transcript Variant: This variant (1) represents the shortest transcript and encodes the functional protein. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.257055.1, SRR1803611.172737.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000523731.6/ ENSP00000430338.1 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAGCGCGG AGGCGGCGGA CCGGGAGGCG GCCACCTCCA GCCGGCCCTG CACCCCGCCG 
CAGACCTGCT GGTTTGAGTT TCTGCTGGAG GAGTCACTGT TGGAGAAACA TCTGCGCAAG 
CCCTGCCCGG ATCCTGCACC AGTTCAACTT ATAGTTCAGT TTTTGGAACA GGCTTCCAAA 
CCTTCAGTTA ATGAACAAAA CCAAGTTCAA CCTCCGCCTG ATAACAAGAG AAATCGTATT 
TTAAAACTAC TTGCTCTTAA AGTTGCTGCA CATTTGAAGT GGGACTTAGA CATATTAGAG 
AAAAGTTTGT CTGTTCCAGT ATTGAATATG CTACTAAATG AACTACTCTG CATCAGTAAA 
GTTCCTCCTG GGACAAAGCA TGTAGACATG GATCTGGCCA CTTTACCTCC GACCACTGCC 
ATGGCTGTAC TTCTCTATAA TAGATGGGCA ATTAGGACAA TTGTTCAAAG TAGTTTTCCA 
GTCAAACAGG CAAAACCCGG ACCCCCTCAG TTAAGTGTTA TGAATCAAAT GCAACAGGAA 
AAAGAGCTAA CAGAAAACAT TTTGAAAGTG CTCAAAGAAC AAGCTGCTGA TTCTATTTTG 
GTACTAGAAG CAGCCCTAAA ATTAAACAAG GATCTTTATG TCCATACGAT GAGAACTCTA 
GATTTATTGG CCATGGAACC AGGCATGGTA AATGGAGAAA CTGAGAGTTC TACTGCTGGA 
TTGAAAGTCA AAACCGAAGA AATGCAGTGC CAGGTGTGCT ATGATTTGGG CGCAGCATAC 
TTCCAGCAAG GCTCCACAAA TTCAGCTGTC TATGAAAATG CCAGGGAAAA ATTTTTTAGA 
ACCAAAGAAC TAATTGCAGA GATAGGTTCA TTATCTCTTC ATTGTACCAT AGATGAGAAG 
CGGTTAGCTG GCTATTGTCA AGCATGTGAT GTTCTTGTAC CTTCTTCTGA TAGTACATCT 
CAACAGTTGA CTCCATATAG TCAAGTCCAT ATTTGTTTGA GATCTGGCAA CTATCAGGAG 
GTAATACAGA TTTTCATTGA AGACAACTTA ACCTTGAGTT TACCTGTCCA GTTCCGACAG 
TCAGTCCTAA GAGAACTCTT TAAGAAAGCT CAACAGGGAA ATGAAGCTCT AGATGAAATC 
TGTTTTAAAG TTTGTGCCTG TAATACAGTC CGTGATATAC TGGAAGGCAG AACAATTAGT 
GTTCAATTTA ACCAGCTATT TCTTAGACCA AATAAAGAGA AAATAGACTT TCTTCTTGAG 
GTATGTTCAA GATCAGTAAA TTTAGAAAAA GCTTCAGAGT CTTTGAAAGG AAACATGGCT 
GCTTTTCTAA AGAATGTGTG TCTGGGGTTG GAAGATCTGC AGTATGTTTT CATGATTTCT 
TCACATGAGC TTTTCATTAC ATTGTTGAAA GATGAAGAAC GAAAGCTACT TGTTGATCAG 
ATGAGGAAGA GATCCCCTAG AGTAAATCTG TGCATTAAAC CTGTAACTTC ATTTTATGAT 
ATCCCAGCTT CAGCAAGTGT CAACATTGGT CAGTTAGAGC ATCAACTTAT ATTGTCAGTG 
GATCCTTGGA GGATTAGACA AATTTTAATT GAATTACATG GTATGACTTC AGAGCGCCAG 
TTCTGGACAG TGTCTAATAA GTGGGAAGTA CCTTCTGTCT ATAGTGGTGT TATCCTGGGA 
ATTAAAGACA ATTTAACAAG AGATTTGGTT TATATTCTTA TGGCCAAAGG TTTGCACTGC 
AGTACTGTTA AGGACTTTTC CCATGCTAAA CAGCTCTTTG CTGCTTGTTT GGAGTTGGTA 
ACAGAGTTCT CACCGAAGCT TCGTCAGGTC ATGCTGAATG AGATGTTGCT TTTGGATATT 
CATACACACG AAGCTGGGAC AGGGCAGGCA GGAGAGAGAC CGCCATCCGA CCTTATAAGT 
AGAGTACGAG GCTATCTGGA AATGAGGCTT CCTGATATTC CTCTTCGTCA AGTTATAGCT 
GAGGAATGTG TTGCCTTTAT GTTAAACTGG AGAGAAAATG AATACCTTAC ACTCCAAGTT 
CCTGCATTTT TGCTTCAGAG TAATCCATAT GTAAAGCTTG GACAGCTTTT AGCAGCTACA 
TGCAAAGAAC TTCCAGGCCC TAAAGAAAGT AGACGGACTG CCAAAGACCT TTGGGAAGTT 
GTTGTTCAAA TCTGTAGTGT GTCCAGTCAG CACAAACGAG GAAATGATGG CAGAGTTAGT 
TTAATAAAAC AGAGGGAATC TACGTTAGGT ATCATGTATC GGAGTGAACT GCTTTCTTTT 
ATCAAAAAAT TACGAGAACC ACTCGTTTTG ACTATTATTT TATCACTCTT TGTGAAACTT 
CACAATGTTC GGGAGGACAT TGTGAATGAT ATTACAGCTG AACACATTTC TATTTGGCCA 
TCTTCCATTC CCAACCTCCA GTCTGTGGAC TTTGAAGCTG TGGCAATCAC AGTGAAAGAG 
CTAGTTCGAT ATACACTCAG TATAAATCCA AATAACCATT CTTGGTTAAT TATCCAGGCA 
GATATTTACT TTGCAACGAA TCAGTATTCA GCAGCTCTTC ACTATTACCT CCAGGCAGGA 
GCTGTGTGTT CTGACTTCTT TAACAAGGCT GTGCCCCCTG ATGTTTATAC AGACCAGGTA 
ATAAAACGAA TGATAAAATG TTGTTCTTTG CTGAATTGCC ACACACAGGT GGCCATTTTA 
TGTCAGTTCC TCAGAGAAAT TGACTACAAA ACAGCGTTTA AATCTCTGCA AGAACAAAAC 
AGTCATGATG CTATGGACTC CTACTACGAC TACATATGGG ATGTTACCAT TTTGGAATAC 
TTGACTTATC TTCATCATAA AAGAGGAGAA ACAGATAAAA GACAAATTGC AATCAAAGCC 
ATCGGCCAGA CAGAGTTGAA TGCAAGCAAT CCAGAAGAAG TGTTACAGCT GGCAGCGCAG 
AGAAGGAAAA AAAAGTTTCT CCAAGCAATG GCAAAACTTT ACTTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060334.2
CDS	146..3133
Translation	MSAEAADREAATSSRPCTPPQTCWFEFLLEESLLEKHLRKPCPDPAPVQLIVQFLEQASKPSVNEQNQVQPPPDNKRNRILKLLALKVAAHLKWDLDILEKSLSVPVLNMLLNELLCISKVPPGTKHVDMDLATLPPTTAMAVLLYNRWAIRTIVQSSFPVKQAKPGPPQLSVMNQMQQEKELTENILKVLKEQAADSILVLEAALKLNKDLYVHTMRTLDLLAMEPGMVNGETESSTAGLKVKTEEMQCQVCYDLGAAYFQQGSTNSAVYENAREKFFRTKELIAEIGSLSLHCTIDEKRLAGYCQACDVLVPSSDSTSQQLTPYSQVHICLRSGNYQEVIQIFIEDNLTLSLPVQFRQSVLRELFKKAQQGNEALDEICFKVCACNTVRDILEGRTISVQFNQLFLRPNKEKIDFLLEVCSRSVNLEKASESLKGNMAAFLKNVCLGLEDLQYVFMISSHELFITLLKDEERKLLVDQMRKRSPRVNLCIKPVTSFYDIPASASVNIGQLEHQLILSVDPWRIRQILIELHGMTSERQFWTVSNKWEVPSVYSGVILGIKDNLTRDLVYILMAKGLHCSTVKDFSHAKQLFAACLELVTEFSPKLRQVMLNEMLLLDIHTHEAGTGQAGERPPSDLISRVRGYLEMRLPDIPLRQVIAEECVAFMLNWRENEYLTLQVPAFLLQSNPYVKLGQLLAATCKELPGPKESRRTAKDLWEVVVQICSVSSQHKRGNDGRVSLIKQRESTLGIMYRSELLSFIKKLREPLVLTIILSLFVKLHNVREDIVNDITAEHISIWPSSIPNLQSVDFEAVAITVKELVRYTLSINPNNHSWLIIQADIYFATNQYSAALHYYLQAGAVCSDFFNKAVPPDVYTDQVIKRMIKCCSLLNCHTQVAILCQFLREIDYKTAFKSLQEQNSHDAMDSYYDYIWDVTILEYLTYLHHKRGETDKRQIAIKAIGQTELNASNPEEVLQLAAQRRKKKFLQAMAKLYF

Target ORF information:

RefSeq Version	NM_017864.4
Organism	Homo sapiens(human)
Definition	Homo sapiens integrator complex subunit 8 (INTS8), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_017864.4

ORF Insert Sequence:

ATGAGCGCGG AGGCGGCGGA CCGGGAGGCG GCCACCTCCA GCCGGCCCTG CACCCCGCCG 
CAGACCTGCT GGTTTGAGTT TCTGCTGGAG GAGTCACTGT TGGAGAAACA TCTGCGCAAG 
CCCTGCCCGG ATCCTGCACC AGTTCAACTT ATAGTTCAGT TTTTGGAACA GGCTTCCAAA 
CCTTCAGTTA ATGAACAAAA CCAAGTTCAA CCTCCGCCTG ATAACAAGAG AAATCGTATT 
TTAAAACTAC TTGCTCTTAA AGTTGCTGCA CATTTGAAGT GGGACTTAGA CATATTAGAG 
AAAAGTTTGT CTGTTCCAGT ATTGAATATG CTACTAAATG AACTACTCTG CATCAGTAAA 
GTTCCTCCTG GGACAAAGCA TGTAGACATG GATCTGGCCA CTTTACCTCC GACCACTGCC 
ATGGCTGTAC TTCTCTATAA TAGATGGGCA ATTAGGACAA TTGTTCAAAG TAGTTTTCCA 
GTCAAACAGG CAAAACCCGG ACCCCCTCAG TTAAGTGTTA TGAATCAAAT GCAACAGGAA 
AAAGAGCTAA CAGAAAACAT TTTGAAAGTG CTCAAAGAAC AAGCTGCTGA TTCTATTTTG 
GTACTAGAAG CAGCCCTAAA ATTAAACAAG GATCTTTATG TCCATACGAT GAGAACTCTA 
GATTTATTGG CCATGGAACC AGGCATGGTA AATGGAGAAA CTGAGAGTTC TACTGCTGGA 
TTGAAAGTCA AAACCGAAGA AATGCAGTGC CAGGTGTGCT ATGATTTGGG CGCAGCATAC 
TTCCAGCAAG GCTCCACAAA TTCAGCTGTC TATGAAAATG CCAGGGAAAA ATTTTTTAGA 
ACCAAAGAAC TAATTGCAGA GATAGGTTCA TTATCTCTTC ATTGTACCAT AGATGAGAAG 
CGGTTAGCTG GCTATTGTCA AGCATGTGAT GTTCTTGTAC CTTCTTCTGA TAGTACATCT 
CAACAGTTGA CTCCATATAG TCAAGTCCAT ATTTGTTTGA GATCTGGCAA CTATCAGGAG 
GTAATACAGA TTTTCATTGA AGACAACTTA ACCTTGAGTT TACCTGTCCA GTTCCGACAG 
TCAGTCCTAA GAGAACTCTT TAAGAAAGCT CAACAGGGAA ATGAAGCTCT AGATGAAATC 
TGTTTTAAAG TTTGTGCCTG TAATACAGTC CGTGATATAC TGGAAGGCAG AACAATTAGT 
GTTCAATTTA ACCAGCTATT TCTTAGACCA AATAAAGAGA AAATAGACTT TCTTCTTGAG 
GTATGTTCAA GATCAGTAAA TTTAGAAAAA GCTTCAGAGT CTTTGAAAGG AAACATGGCT 
GCTTTTCTAA AGAATGTGTG TCTGGGGTTG GAAGATCTGC AGTATGTTTT CATGATTTCT 
TCACATGAGC TTTTCATTAC ATTGTTGAAA GATGAAGAAC GAAAGCTACT TGTTGATCAG 
ATGAGGAAGA GATCCCCTAG AGTAAATCTG TGCATTAAAC CTGTAACTTC ATTTTATGAT 
ATCCCAGCTT CAGCAAGTGT CAACATTGGT CAGTTAGAGC ATCAACTTAT ATTGTCAGTG 
GATCCTTGGA GGATTAGACA AATTTTAATT GAATTACATG GTATGACTTC AGAGCGCCAG 
TTCTGGACAG TGTCTAATAA GTGGGAAGTA CCTTCTGTCT ATAGTGGTGT TATCCTGGGA 
ATTAAAGACA ATTTAACAAG AGATTTGGTT TATATTCTTA TGGCCAAAGG TTTGCACTGC 
AGTACTGTTA AGGACTTTTC CCATGCTAAA CAGCTCTTTG CTGCTTGTTT GGAGTTGGTA 
ACAGAGTTCT CACCGAAGCT TCGTCAGGTC ATGCTGAATG AGATGTTGCT TTTGGATATT 
CATACACACG AAGCTGGGAC AGGGCAGGCA GGAGAGAGAC CGCCATCCGA CCTTATAAGT 
AGAGTACGAG GCTATCTGGA AATGAGGCTT CCTGATATTC CTCTTCGTCA AGTTATAGCT 
GAGGAATGTG TTGCCTTTAT GTTAAACTGG AGAGAAAATG AATACCTTAC ACTCCAAGTT 
CCTGCATTTT TGCTTCAGAG TAATCCATAT GTAAAGCTTG GACAGCTTTT AGCAGCTACA 
TGCAAAGAAC TTCCAGGCCC TAAAGAAAGT AGACGGACTG CCAAAGACCT TTGGGAAGTT 
GTTGTTCAAA TCTGTAGTGT GTCCAGTCAG CACAAACGAG GAAATGATGG CAGAGTTAGT 
TTAATAAAAC AGAGGGAATC TACGTTAGGT ATCATGTATC GGAGTGAACT GCTTTCTTTT 
ATCAAAAAAT TACGAGAACC ACTCGTTTTG ACTATTATTT TATCACTCTT TGTGAAACTT 
CACAATGTTC GGGAGGACAT TGTGAATGAT ATTACAGCTG AACACATTTC TATTTGGCCA 
TCTTCCATTC CCAACCTCCA GTCTGTGGAC TTTGAAGCTG TGGCAATCAC AGTGAAAGAG 
CTAGTTCGAT ATACACTCAG TATAAATCCA AATAACCATT CTTGGTTAAT TATCCAGGCA 
GATATTTACT TTGCAACGAA TCAGTATTCA GCAGCTCTTC ACTATTACCT CCAGGCAGGA 
GCTGTGTGTT CTGACTTCTT TAACAAGGCT GTGCCCCCTG ATGTTTATAC AGACCAGGTA 
ATAAAACGAA TGATAAAATG TTGTTCTTTG CTGAATTGCC ACACACAGGT GGCCATTTTA 
TGTCAGTTCC TCAGAGAAAT TGACTACAAA ACAGCGTTTA AATCTCTGCA AGAACAAAAC 
AGTCATGATG CTATGGACTC CTACTACGAC TACATATGGG ATGTTACCAT TTTGGAATAC 
TTGACTTATC TTCATCATAA AAGAGGAGAA ACAGATAAAA GACAAATTGC AATCAAAGCC 
ATCGGCCAGA CAGAGTTGAA TGCAAGCAAT CCAGAAGAAG TGTTACAGCT GGCAGCGCAG 
AGAAGGAAAA AAAAGTTTCT CCAAGCAATG GCAAAACTTT ACTTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

INTS8 ( NM_017864.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_060334.2 Homo sapiens integrator complex subunit 8 (INTS8), transcript variant 1, mRNA.

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CloneID	OHu00549
Clone ID Related Accession (Same CDS sequence)	NM_017864.4 , NM_017864.3
Accession Version	NM_017864.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2988bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Homo sapiens(human)
Product	integrator complex subunit 8
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA644524.1, AB161944.1 and BC136754.1. This sequence is a reference standard in the RefSeqGene project. On Nov 21, 2012 this sequence version replaced NM_017864.2. Transcript Variant: This variant (1) represents the shortest transcript and encodes the functional protein. ##Evidence-Data-START## Transcript exon combination :: AB161944.1, SRR1803617.226874.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGCGCGG AGGCGGCGGA CCGGGAGGCG GCCACCTCCA GCCGGCCCTG CACCCCGCCG 
CAGACCTGCT GGTTTGAGTT TCTGCTGGAG GAGTCACTGT TGGAGAAACA TCTGCGCAAG 
CCCTGCCCGG ATCCTGCACC AGTTCAACTT ATAGTTCAGT TTTTGGAACA GGCTTCCAAA 
CCTTCAGTTA ATGAACAAAA CCAAGTTCAA CCTCCGCCTG ATAACAAGAG AAATCGTATT 
TTAAAACTAC TTGCTCTTAA AGTTGCTGCA CATTTGAAGT GGGACTTAGA CATATTAGAG 
AAAAGTTTGT CTGTTCCAGT ATTGAATATG CTACTAAATG AACTACTCTG CATCAGTAAA 
GTTCCTCCTG GGACAAAGCA TGTAGACATG GATCTGGCCA CTTTACCTCC GACCACTGCC 
ATGGCTGTAC TTCTCTATAA TAGATGGGCA ATTAGGACAA TTGTTCAAAG TAGTTTTCCA 
GTCAAACAGG CAAAACCCGG ACCCCCTCAG TTAAGTGTTA TGAATCAAAT GCAACAGGAA 
AAAGAGCTAA CAGAAAACAT TTTGAAAGTG CTCAAAGAAC AAGCTGCTGA TTCTATTTTG 
GTACTAGAAG CAGCCCTAAA ATTAAACAAG GATCTTTATG TCCATACGAT GAGAACTCTA 
GATTTATTGG CCATGGAACC AGGCATGGTA AATGGAGAAA CTGAGAGTTC TACTGCTGGA 
TTGAAAGTCA AAACCGAAGA AATGCAGTGC CAGGTGTGCT ATGATTTGGG CGCAGCATAC 
TTCCAGCAAG GCTCCACAAA TTCAGCTGTC TATGAAAATG CCAGGGAAAA ATTTTTTAGA 
ACCAAAGAAC TAATTGCAGA GATAGGTTCA TTATCTCTTC ATTGTACCAT AGATGAGAAG 
CGGTTAGCTG GCTATTGTCA AGCATGTGAT GTTCTTGTAC CTTCTTCTGA TAGTACATCT 
CAACAGTTGA CTCCATATAG TCAAGTCCAT ATTTGTTTGA GATCTGGCAA CTATCAGGAG 
GTAATACAGA TTTTCATTGA AGACAACTTA ACCTTGAGTT TACCTGTCCA GTTCCGACAG 
TCAGTCCTAA GAGAACTCTT TAAGAAAGCT CAACAGGGAA ATGAAGCTCT AGATGAAATC 
TGTTTTAAAG TTTGTGCCTG TAATACAGTC CGTGATATAC TGGAAGGCAG AACAATTAGT 
GTTCAATTTA ACCAGCTATT TCTTAGACCA AATAAAGAGA AAATAGACTT TCTTCTTGAG 
GTATGTTCAA GATCAGTAAA TTTAGAAAAA GCTTCAGAGT CTTTGAAAGG AAACATGGCT 
GCTTTTCTAA AGAATGTGTG TCTGGGGTTG GAAGATCTGC AGTATGTTTT CATGATTTCT 
TCACATGAGC TTTTCATTAC ATTGTTGAAA GATGAAGAAC GAAAGCTACT TGTTGATCAG 
ATGAGGAAGA GATCCCCTAG AGTAAATCTG TGCATTAAAC CTGTAACTTC ATTTTATGAT 
ATCCCAGCTT CAGCAAGTGT CAACATTGGT CAGTTAGAGC ATCAACTTAT ATTGTCAGTG 
GATCCTTGGA GGATTAGACA AATTTTAATT GAATTACATG GTATGACTTC AGAGCGCCAG 
TTCTGGACAG TGTCTAATAA GTGGGAAGTA CCTTCTGTCT ATAGTGGTGT TATCCTGGGA 
ATTAAAGACA ATTTAACAAG AGATTTGGTT TATATTCTTA TGGCCAAAGG TTTGCACTGC 
AGTACTGTTA AGGACTTTTC CCATGCTAAA CAGCTCTTTG CTGCTTGTTT GGAGTTGGTA 
ACAGAGTTCT CACCGAAGCT TCGTCAGGTC ATGCTGAATG AGATGTTGCT TTTGGATATT 
CATACACACG AAGCTGGGAC AGGGCAGGCA GGAGAGAGAC CGCCATCCGA CCTTATAAGT 
AGAGTACGAG GCTATCTGGA AATGAGGCTT CCTGATATTC CTCTTCGTCA AGTTATAGCT 
GAGGAATGTG TTGCCTTTAT GTTAAACTGG AGAGAAAATG AATACCTTAC ACTCCAAGTT 
CCTGCATTTT TGCTTCAGAG TAATCCATAT GTAAAGCTTG GACAGCTTTT AGCAGCTACA 
TGCAAAGAAC TTCCAGGCCC TAAAGAAAGT AGACGGACTG CCAAAGACCT TTGGGAAGTT 
GTTGTTCAAA TCTGTAGTGT GTCCAGTCAG CACAAACGAG GAAATGATGG CAGAGTTAGT 
TTAATAAAAC AGAGGGAATC TACGTTAGGT ATCATGTATC GGAGTGAACT GCTTTCTTTT 
ATCAAAAAAT TACGAGAACC ACTCGTTTTG ACTATTATTT TATCACTCTT TGTGAAACTT 
CACAATGTTC GGGAGGACAT TGTGAATGAT ATTACAGCTG AACACATTTC TATTTGGCCA 
TCTTCCATTC CCAACCTCCA GTCTGTGGAC TTTGAAGCTG TGGCAATCAC AGTGAAAGAG 
CTAGTTCGAT ATACACTCAG TATAAATCCA AATAACCATT CTTGGTTAAT TATCCAGGCA 
GATATTTACT TTGCAACGAA TCAGTATTCA GCAGCTCTTC ACTATTACCT CCAGGCAGGA 
GCTGTGTGTT CTGACTTCTT TAACAAGGCT GTGCCCCCTG ATGTTTATAC AGACCAGGTA 
ATAAAACGAA TGATAAAATG TTGTTCTTTG CTGAATTGCC ACACACAGGT GGCCATTTTA 
TGTCAGTTCC TCAGAGAAAT TGACTACAAA ACAGCGTTTA AATCTCTGCA AGAACAAAAC 
AGTCATGATG CTATGGACTC CTACTACGAC TACATATGGG ATGTTACCAT TTTGGAATAC 
TTGACTTATC TTCATCATAA AAGAGGAGAA ACAGATAAAA GACAAATTGC AATCAAAGCC 
ATCGGCCAGA CAGAGTTGAA TGCAAGCAAT CCAGAAGAAG TGTTACAGCT GGCAGCGCAG 
AGAAGGAAAA AAAAGTTTCT CCAAGCAATG GCAAAACTTT ACTTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060334.2
CDS	143..3130
Translation	MSAEAADREAATSSRPCTPPQTCWFEFLLEESLLEKHLRKPCPDPAPVQLIVQFLEQASKPSVNEQNQVQPPPDNKRNRILKLLALKVAAHLKWDLDILEKSLSVPVLNMLLNELLCISKVPPGTKHVDMDLATLPPTTAMAVLLYNRWAIRTIVQSSFPVKQAKPGPPQLSVMNQMQQEKELTENILKVLKEQAADSILVLEAALKLNKDLYVHTMRTLDLLAMEPGMVNGETESSTAGLKVKTEEMQCQVCYDLGAAYFQQGSTNSAVYENAREKFFRTKELIAEIGSLSLHCTIDEKRLAGYCQACDVLVPSSDSTSQQLTPYSQVHICLRSGNYQEVIQIFIEDNLTLSLPVQFRQSVLRELFKKAQQGNEALDEICFKVCACNTVRDILEGRTISVQFNQLFLRPNKEKIDFLLEVCSRSVNLEKASESLKGNMAAFLKNVCLGLEDLQYVFMISSHELFITLLKDEERKLLVDQMRKRSPRVNLCIKPVTSFYDIPASASVNIGQLEHQLILSVDPWRIRQILIELHGMTSERQFWTVSNKWEVPSVYSGVILGIKDNLTRDLVYILMAKGLHCSTVKDFSHAKQLFAACLELVTEFSPKLRQVMLNEMLLLDIHTHEAGTGQAGERPPSDLISRVRGYLEMRLPDIPLRQVIAEECVAFMLNWRENEYLTLQVPAFLLQSNPYVKLGQLLAATCKELPGPKESRRTAKDLWEVVVQICSVSSQHKRGNDGRVSLIKQRESTLGIMYRSELLSFIKKLREPLVLTIILSLFVKLHNVREDIVNDITAEHISIWPSSIPNLQSVDFEAVAITVKELVRYTLSINPNNHSWLIIQADIYFATNQYSAALHYYLQAGAVCSDFFNKAVPPDVYTDQVIKRMIKCCSLLNCHTQVAILCQFLREIDYKTAFKSLQEQNSHDAMDSYYDYIWDVTILEYLTYLHHKRGETDKRQIAIKAIGQTELNASNPEEVLQLAAQRRKKKFLQAMAKLYF

Target ORF information:

RefSeq Version	NM_017864.3
Organism	Homo sapiens(human)
Definition	Homo sapiens integrator complex subunit 8 (INTS8), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_017864.3

ORF Insert Sequence:

ATGAGCGCGG AGGCGGCGGA CCGGGAGGCG GCCACCTCCA GCCGGCCCTG CACCCCGCCG 
CAGACCTGCT GGTTTGAGTT TCTGCTGGAG GAGTCACTGT TGGAGAAACA TCTGCGCAAG 
CCCTGCCCGG ATCCTGCACC AGTTCAACTT ATAGTTCAGT TTTTGGAACA GGCTTCCAAA 
CCTTCAGTTA ATGAACAAAA CCAAGTTCAA CCTCCGCCTG ATAACAAGAG AAATCGTATT 
TTAAAACTAC TTGCTCTTAA AGTTGCTGCA CATTTGAAGT GGGACTTAGA CATATTAGAG 
AAAAGTTTGT CTGTTCCAGT ATTGAATATG CTACTAAATG AACTACTCTG CATCAGTAAA 
GTTCCTCCTG GGACAAAGCA TGTAGACATG GATCTGGCCA CTTTACCTCC GACCACTGCC 
ATGGCTGTAC TTCTCTATAA TAGATGGGCA ATTAGGACAA TTGTTCAAAG TAGTTTTCCA 
GTCAAACAGG CAAAACCCGG ACCCCCTCAG TTAAGTGTTA TGAATCAAAT GCAACAGGAA 
AAAGAGCTAA CAGAAAACAT TTTGAAAGTG CTCAAAGAAC AAGCTGCTGA TTCTATTTTG 
GTACTAGAAG CAGCCCTAAA ATTAAACAAG GATCTTTATG TCCATACGAT GAGAACTCTA 
GATTTATTGG CCATGGAACC AGGCATGGTA AATGGAGAAA CTGAGAGTTC TACTGCTGGA 
TTGAAAGTCA AAACCGAAGA AATGCAGTGC CAGGTGTGCT ATGATTTGGG CGCAGCATAC 
TTCCAGCAAG GCTCCACAAA TTCAGCTGTC TATGAAAATG CCAGGGAAAA ATTTTTTAGA 
ACCAAAGAAC TAATTGCAGA GATAGGTTCA TTATCTCTTC ATTGTACCAT AGATGAGAAG 
CGGTTAGCTG GCTATTGTCA AGCATGTGAT GTTCTTGTAC CTTCTTCTGA TAGTACATCT 
CAACAGTTGA CTCCATATAG TCAAGTCCAT ATTTGTTTGA GATCTGGCAA CTATCAGGAG 
GTAATACAGA TTTTCATTGA AGACAACTTA ACCTTGAGTT TACCTGTCCA GTTCCGACAG 
TCAGTCCTAA GAGAACTCTT TAAGAAAGCT CAACAGGGAA ATGAAGCTCT AGATGAAATC 
TGTTTTAAAG TTTGTGCCTG TAATACAGTC CGTGATATAC TGGAAGGCAG AACAATTAGT 
GTTCAATTTA ACCAGCTATT TCTTAGACCA AATAAAGAGA AAATAGACTT TCTTCTTGAG 
GTATGTTCAA GATCAGTAAA TTTAGAAAAA GCTTCAGAGT CTTTGAAAGG AAACATGGCT 
GCTTTTCTAA AGAATGTGTG TCTGGGGTTG GAAGATCTGC AGTATGTTTT CATGATTTCT 
TCACATGAGC TTTTCATTAC ATTGTTGAAA GATGAAGAAC GAAAGCTACT TGTTGATCAG 
ATGAGGAAGA GATCCCCTAG AGTAAATCTG TGCATTAAAC CTGTAACTTC ATTTTATGAT 
ATCCCAGCTT CAGCAAGTGT CAACATTGGT CAGTTAGAGC ATCAACTTAT ATTGTCAGTG 
GATCCTTGGA GGATTAGACA AATTTTAATT GAATTACATG GTATGACTTC AGAGCGCCAG 
TTCTGGACAG TGTCTAATAA GTGGGAAGTA CCTTCTGTCT ATAGTGGTGT TATCCTGGGA 
ATTAAAGACA ATTTAACAAG AGATTTGGTT TATATTCTTA TGGCCAAAGG TTTGCACTGC 
AGTACTGTTA AGGACTTTTC CCATGCTAAA CAGCTCTTTG CTGCTTGTTT GGAGTTGGTA 
ACAGAGTTCT CACCGAAGCT TCGTCAGGTC ATGCTGAATG AGATGTTGCT TTTGGATATT 
CATACACACG AAGCTGGGAC AGGGCAGGCA GGAGAGAGAC CGCCATCCGA CCTTATAAGT 
AGAGTACGAG GCTATCTGGA AATGAGGCTT CCTGATATTC CTCTTCGTCA AGTTATAGCT 
GAGGAATGTG TTGCCTTTAT GTTAAACTGG AGAGAAAATG AATACCTTAC ACTCCAAGTT 
CCTGCATTTT TGCTTCAGAG TAATCCATAT GTAAAGCTTG GACAGCTTTT AGCAGCTACA 
TGCAAAGAAC TTCCAGGCCC TAAAGAAAGT AGACGGACTG CCAAAGACCT TTGGGAAGTT 
GTTGTTCAAA TCTGTAGTGT GTCCAGTCAG CACAAACGAG GAAATGATGG CAGAGTTAGT 
TTAATAAAAC AGAGGGAATC TACGTTAGGT ATCATGTATC GGAGTGAACT GCTTTCTTTT 
ATCAAAAAAT TACGAGAACC ACTCGTTTTG ACTATTATTT TATCACTCTT TGTGAAACTT 
CACAATGTTC GGGAGGACAT TGTGAATGAT ATTACAGCTG AACACATTTC TATTTGGCCA 
TCTTCCATTC CCAACCTCCA GTCTGTGGAC TTTGAAGCTG TGGCAATCAC AGTGAAAGAG 
CTAGTTCGAT ATACACTCAG TATAAATCCA AATAACCATT CTTGGTTAAT TATCCAGGCA 
GATATTTACT TTGCAACGAA TCAGTATTCA GCAGCTCTTC ACTATTACCT CCAGGCAGGA 
GCTGTGTGTT CTGACTTCTT TAACAAGGCT GTGCCCCCTG ATGTTTATAC AGACCAGGTA 
ATAAAACGAA TGATAAAATG TTGTTCTTTG CTGAATTGCC ACACACAGGT GGCCATTTTA 
TGTCAGTTCC TCAGAGAAAT TGACTACAAA ACAGCGTTTA AATCTCTGCA AGAACAAAAC 
AGTCATGATG CTATGGACTC CTACTACGAC TACATATGGG ATGTTACCAT TTTGGAATAC 
TTGACTTATC TTCATCATAA AAGAGGAGAA ACAGATAAAA GACAAATTGC AATCAAAGCC 
ATCGGCCAGA CAGAGTTGAA TGCAAGCAAT CCAGAAGAAG TGTTACAGCT GGCAGCGCAG 
AGAAGGAAAA AAAAGTTTCT CCAAGCAATG GCAAAACTTT ACTTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

INTS8 ( XM_017013616.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016869105.1 Homo sapiens integrator complex subunit 8 (INTS8), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu98094
Clone ID Related Accession (Same CDS sequence)	XM_017013616.1
Accession Version	XM_017013616.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2958bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	integrator complex subunit 8 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGCGCGG AGGCGGCGGA CCGGGAGGCG GCCACCTCCA GCCGGCCCTG CACCCCGCCG 
CAGACCTGCT GGTTTGAGTT TCTGCTGGAG GAGTCACTGT TGGAGAAACA TCTGCGCAAG 
CCCTGCCCGG ATCCTGCACC AGTTCAACTT ATAGTTCAGT TTTTGGAACA GGCTTCCAAA 
CCTTCAGTTA ATGAACAAAA CCAAGTTCAA CCTCCGCCTG ATAACAAGAG AAATCGTATT 
TTAAAACTAC TTGCTCTTAA AGTTGCTGCA CATTTGAAGT GGGACTTAGA CATATTAGAG 
AAAAGTTTGT CTGTTCCAGT ATTGAATATG CTACTAAATG AACTACTCTG CATCAGTAAA 
GTTCCTCCTG GGACAAAGCA TGTAGACATG GATCTGGCCA CTTTACCTCC GACCACTGCC 
ATGGCTGTAC TTCTCTATAA TAGATGGGCA ATTAGGACAA TTGTTCAAAG TAGTTTTCCA 
GTCAAACAGG CAAAACCCGG ACCCCCTCAG TTAAGTGTTA TGAATCAAAT GCAACAGGAA 
AAAGAGCTAA CAGAAAACAT TTTGAAAGTG CTCAAAGAAC AAGCTGCTGA TTCTATTTTG 
GTACTAGAAG CAGCCCTAAA ATTAAACAAG GATCTTTATG TCCATACGAT GAGAACTCTA 
GATTTATTGG CCATGGAACC AGGCATGGTA AATGGAGAAA CTGAGAGTTC TACTGCTGGA 
TTGAAAGTCA AAACCGAAGA AATGCAGTGC CAGGTGTGCT ATGATTTGGG CGCAGCATAC 
TTCCAGCAAG GCTCCACAAA TTCAGCTGTC TATGAAAATG CCAGGGAAAA ATTTTTTAGA 
ACCAAAGAAC TAATTGCAGA GATAGGTTCA TTATCTCTTC ATTGTACCAT AGATGAGAAG 
CGGTTAGCTG GCTATTGTCA AGCATGTGAT GTTCTTGTAC CTTCTTCTGA TAGTACATCT 
CAACAGTTGA CTCCATATAG TCAAGTCCAT ATTTGTTTGA GATCTGGCAA CTATCAGGAG 
GTAATACAGA TTTTCATTGA AGACAACTTA ACCTTGAGTT TACCTGTCCA GTTCCGACAG 
TCAGTCCTAA GAGAACTCTT TAAGAAAGCT CAACAGGGAA ATGAAGCTCT AGATGAAATC 
TGTTTTAAAG TTTGTGCCTG TAATACAGTC CGTGATATAC TGGAAGGCAG AACAATTAGT 
GTTCAATTTA ACCAGCTATT TCTTAGACCA AATAAAGAGA AAATAGACTT TCTTCTTGAG 
GTATGTTCAA GATCAGTAAA TTTAGAAAAA GCTTCAGAGT CTTTGAAAGG AAACATGGCT 
GCTTTTCTAA AGAATGTGTG TCTGGGGTTG GAAGATCTGC AGTATGTTTT CATGATTTCT 
TCACATGAGC TTTTCATTAC ATTGTTGAAA GATGAAGAAC GAAAGCTACT TGTTGATCAG 
ATGAGGAAGA GATCCCCTAG AGTAAATCTG TGCATTAAAC CTGTAACTTC ATTTTATGAT 
ATCCCAGCTT CAGCAAGTGT CAACATTGGT CAGTTAGAGC ATCAACTTAT ATTGTCAGTG 
GATCCTTGGA GGATTAGACA AATTTTAATT GAATTACATG GTATGACTTC AGAGCGCCAG 
TTCTGGACAG TGTCTAATAA GTGGGAAGTA CCTTCTGTCT ATAGTGGTGT TATCCTGGGA 
ATTAAAGACA ATTTAACAAG AGATTTGGTT TATATTCTTA TGGCCAAAGG TTTGCACTGC 
AGTACTGTTA AGGACTTTTC CCATGCTAAA CAGCTCTTTG CTGCTTGTTT GGAGTTGGTA 
ACAGAGTTCT CACCGAAGCT TCGTCAGGTC ATGCTGAATG AGATGTTGCT TTTGGATATT 
CATACACACG AAGCTGGGAC AGGGCAGGCA GGAGAGAGAC CGCCATCCGA CCTTATAAGT 
AGAGTACGAG GCTATCTGGA AATGAGGCTT CCTGATATTC CTCTTCGTCA AGTTATAGCT 
GAGGAATGTG TTGCCTTTAT GTTAAACTGG AGAGAAAATG AATACCTTAC ACTCCAAGTT 
CCTGCATTTT TGCTTCAGAG TAATCCATAT GTAAAGCTTG GACAGCTTTT AGCAGCTACA 
TGCAAAGAAC TTCCAGGCCC TAAAGAAAGT AGACGGACTG CCAAAGACCT TTGGGAAGTT 
GTTGTTCAAA TCTGTAGTGT GTCCAGTCAG CACAAACGAG GAAATGATGG CAGAGTTAGT 
TTAATAAAAC AGAGGGAATC TACGTTAGGT ATCATGTATC GGAGTGAACT GCTTTCTTTT 
ATCAAAAAAT TACGAGAACC ACTCGTTTTG ACTATTATTT TATCACTCTT TGTGAAACTT 
CACAATGTTC GGGAGGACAT TGTGAATGAT ATTACAGCTG AACACATTTC TATTTGGCCA 
TCTTCCATTC CCAACCTCCA GTCTGTGGAC TTTGAAGCTG TGGCAATCAC AGTGAAAGAG 
CTAGTTCGAT ATACACTCAG TATAAATCCA AATAACCATT CTTGGTTAAT TATCCAGGCA 
GATATTTACT TTGCAACGAA TCAGTATTCA GCAGCTCTTC ACTATTACCT CCAGGCAGGA 
GCTGTGTGTT CTGACTTCTT TAACAAGGCT GTGCCCCCTG ATGTTTATAC AGACCAGGTA 
ATAAAACGAA TGATAAAATG TTGTTCTTTG CTGAATTGCC ACACACAGGT GGCCATTTTA 
TGTCAGTTCC TCAGAGAAAT TGACTACAAA ACAGCGTTTA AATCTCTGCA AGAACAAAAC 
AGTCATGATG CTATGGACTC CTACTACGAC TACATATGGG ATGTTACCAT TTTGGAATAC 
TTGACTTATC TTCATCATAA AAGAGGAGAA ACAGATAAAA GACAAATTGC AGTGTATAAA 
ACCTCTGAAG GGGGGAGAGG AAAAGCCGCA GTCAAGTACA TTGTCATTCA CATTCTCCAA 
GTGCCAGTAA GACGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016869105.1
CDS	143..3100
Translation	MSAEAADREAATSSRPCTPPQTCWFEFLLEESLLEKHLRKPCPDPAPVQLIVQFLEQASKPSVNEQNQVQPPPDNKRNRILKLLALKVAAHLKWDLDILEKSLSVPVLNMLLNELLCISKVPPGTKHVDMDLATLPPTTAMAVLLYNRWAIRTIVQSSFPVKQAKPGPPQLSVMNQMQQEKELTENILKVLKEQAADSILVLEAALKLNKDLYVHTMRTLDLLAMEPGMVNGETESSTAGLKVKTEEMQCQVCYDLGAAYFQQGSTNSAVYENAREKFFRTKELIAEIGSLSLHCTIDEKRLAGYCQACDVLVPSSDSTSQQLTPYSQVHICLRSGNYQEVIQIFIEDNLTLSLPVQFRQSVLRELFKKAQQGNEALDEICFKVCACNTVRDILEGRTISVQFNQLFLRPNKEKIDFLLEVCSRSVNLEKASESLKGNMAAFLKNVCLGLEDLQYVFMISSHELFITLLKDEERKLLVDQMRKRSPRVNLCIKPVTSFYDIPASASVNIGQLEHQLILSVDPWRIRQILIELHGMTSERQFWTVSNKWEVPSVYSGVILGIKDNLTRDLVYILMAKGLHCSTVKDFSHAKQLFAACLELVTEFSPKLRQVMLNEMLLLDIHTHEAGTGQAGERPPSDLISRVRGYLEMRLPDIPLRQVIAEECVAFMLNWRENEYLTLQVPAFLLQSNPYVKLGQLLAATCKELPGPKESRRTAKDLWEVVVQICSVSSQHKRGNDGRVSLIKQRESTLGIMYRSELLSFIKKLREPLVLTIILSLFVKLHNVREDIVNDITAEHISIWPSSIPNLQSVDFEAVAITVKELVRYTLSINPNNHSWLIIQADIYFATNQYSAALHYYLQAGAVCSDFFNKAVPPDVYTDQVIKRMIKCCSLLNCHTQVAILCQFLREIDYKTAFKSLQEQNSHDAMDSYYDYIWDVTILEYLTYLHHKRGETDKRQIAVYKTSEGGRGKAAVKYIVIHILQVPVRR

Target ORF information:

RefSeq Version	XM_017013616.1
Organism	Homo sapiens(human)
Definition	Homo sapiens integrator complex subunit 8 (INTS8), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017013616.1

ORF Insert Sequence:

ATGAGCGCGG AGGCGGCGGA CCGGGAGGCG GCCACCTCCA GCCGGCCCTG CACCCCGCCG 
CAGACCTGCT GGTTTGAGTT TCTGCTGGAG GAGTCACTGT TGGAGAAACA TCTGCGCAAG 
CCCTGCCCGG ATCCTGCACC AGTTCAACTT ATAGTTCAGT TTTTGGAACA GGCTTCCAAA 
CCTTCAGTTA ATGAACAAAA CCAAGTTCAA CCTCCGCCTG ATAACAAGAG AAATCGTATT 
TTAAAACTAC TTGCTCTTAA AGTTGCTGCA CATTTGAAGT GGGACTTAGA CATATTAGAG 
AAAAGTTTGT CTGTTCCAGT ATTGAATATG CTACTAAATG AACTACTCTG CATCAGTAAA 
GTTCCTCCTG GGACAAAGCA TGTAGACATG GATCTGGCCA CTTTACCTCC GACCACTGCC 
ATGGCTGTAC TTCTCTATAA TAGATGGGCA ATTAGGACAA TTGTTCAAAG TAGTTTTCCA 
GTCAAACAGG CAAAACCCGG ACCCCCTCAG TTAAGTGTTA TGAATCAAAT GCAACAGGAA 
AAAGAGCTAA CAGAAAACAT TTTGAAAGTG CTCAAAGAAC AAGCTGCTGA TTCTATTTTG 
GTACTAGAAG CAGCCCTAAA ATTAAACAAG GATCTTTATG TCCATACGAT GAGAACTCTA 
GATTTATTGG CCATGGAACC AGGCATGGTA AATGGAGAAA CTGAGAGTTC TACTGCTGGA 
TTGAAAGTCA AAACCGAAGA AATGCAGTGC CAGGTGTGCT ATGATTTGGG CGCAGCATAC 
TTCCAGCAAG GCTCCACAAA TTCAGCTGTC TATGAAAATG CCAGGGAAAA ATTTTTTAGA 
ACCAAAGAAC TAATTGCAGA GATAGGTTCA TTATCTCTTC ATTGTACCAT AGATGAGAAG 
CGGTTAGCTG GCTATTGTCA AGCATGTGAT GTTCTTGTAC CTTCTTCTGA TAGTACATCT 
CAACAGTTGA CTCCATATAG TCAAGTCCAT ATTTGTTTGA GATCTGGCAA CTATCAGGAG 
GTAATACAGA TTTTCATTGA AGACAACTTA ACCTTGAGTT TACCTGTCCA GTTCCGACAG 
TCAGTCCTAA GAGAACTCTT TAAGAAAGCT CAACAGGGAA ATGAAGCTCT AGATGAAATC 
TGTTTTAAAG TTTGTGCCTG TAATACAGTC CGTGATATAC TGGAAGGCAG AACAATTAGT 
GTTCAATTTA ACCAGCTATT TCTTAGACCA AATAAAGAGA AAATAGACTT TCTTCTTGAG 
GTATGTTCAA GATCAGTAAA TTTAGAAAAA GCTTCAGAGT CTTTGAAAGG AAACATGGCT 
GCTTTTCTAA AGAATGTGTG TCTGGGGTTG GAAGATCTGC AGTATGTTTT CATGATTTCT 
TCACATGAGC TTTTCATTAC ATTGTTGAAA GATGAAGAAC GAAAGCTACT TGTTGATCAG 
ATGAGGAAGA GATCCCCTAG AGTAAATCTG TGCATTAAAC CTGTAACTTC ATTTTATGAT 
ATCCCAGCTT CAGCAAGTGT CAACATTGGT CAGTTAGAGC ATCAACTTAT ATTGTCAGTG 
GATCCTTGGA GGATTAGACA AATTTTAATT GAATTACATG GTATGACTTC AGAGCGCCAG 
TTCTGGACAG TGTCTAATAA GTGGGAAGTA CCTTCTGTCT ATAGTGGTGT TATCCTGGGA 
ATTAAAGACA ATTTAACAAG AGATTTGGTT TATATTCTTA TGGCCAAAGG TTTGCACTGC 
AGTACTGTTA AGGACTTTTC CCATGCTAAA CAGCTCTTTG CTGCTTGTTT GGAGTTGGTA 
ACAGAGTTCT CACCGAAGCT TCGTCAGGTC ATGCTGAATG AGATGTTGCT TTTGGATATT 
CATACACACG AAGCTGGGAC AGGGCAGGCA GGAGAGAGAC CGCCATCCGA CCTTATAAGT 
AGAGTACGAG GCTATCTGGA AATGAGGCTT CCTGATATTC CTCTTCGTCA AGTTATAGCT 
GAGGAATGTG TTGCCTTTAT GTTAAACTGG AGAGAAAATG AATACCTTAC ACTCCAAGTT 
CCTGCATTTT TGCTTCAGAG TAATCCATAT GTAAAGCTTG GACAGCTTTT AGCAGCTACA 
TGCAAAGAAC TTCCAGGCCC TAAAGAAAGT AGACGGACTG CCAAAGACCT TTGGGAAGTT 
GTTGTTCAAA TCTGTAGTGT GTCCAGTCAG CACAAACGAG GAAATGATGG CAGAGTTAGT 
TTAATAAAAC AGAGGGAATC TACGTTAGGT ATCATGTATC GGAGTGAACT GCTTTCTTTT 
ATCAAAAAAT TACGAGAACC ACTCGTTTTG ACTATTATTT TATCACTCTT TGTGAAACTT 
CACAATGTTC GGGAGGACAT TGTGAATGAT ATTACAGCTG AACACATTTC TATTTGGCCA 
TCTTCCATTC CCAACCTCCA GTCTGTGGAC TTTGAAGCTG TGGCAATCAC AGTGAAAGAG 
CTAGTTCGAT ATACACTCAG TATAAATCCA AATAACCATT CTTGGTTAAT TATCCAGGCA 
GATATTTACT TTGCAACGAA TCAGTATTCA GCAGCTCTTC ACTATTACCT CCAGGCAGGA 
GCTGTGTGTT CTGACTTCTT TAACAAGGCT GTGCCCCCTG ATGTTTATAC AGACCAGGTA 
ATAAAACGAA TGATAAAATG TTGTTCTTTG CTGAATTGCC ACACACAGGT GGCCATTTTA 
TGTCAGTTCC TCAGAGAAAT TGACTACAAA ACAGCGTTTA AATCTCTGCA AGAACAAAAC 
AGTCATGATG CTATGGACTC CTACTACGAC TACATATGGG ATGTTACCAT TTTGGAATAC 
TTGACTTATC TTCATCATAA AAGAGGAGAA ACAGATAAAA GACAAATTGC AGTGTATAAA 
ACCTCTGAAG GGGGGAGAGG AAAAGCCGCA GTCAAGTACA TTGTCATTCA CATTCTCCAA 
GTGCCAGTAA GACGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

INTS8 ( XM_017013617.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016869106.1 Homo sapiens integrator complex subunit 8 (INTS8), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu98095
Clone ID Related Accession (Same CDS sequence)	XM_017013617.1
Accession Version	XM_017013617.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2769bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	integrator complex subunit 8 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGCGCGG AGGCGGCGGA CCGGGAGGCG GCCACCTCCA GCCGGCCCTG CACCCCGCCG 
CAGACCTGCT GGTTTGAGTT TCTGCTGGAG GAGTCACTGT TGGAGAAACA TCTGCGCAAG 
CCCTGCCCGG ATCCTGCACC AGTTCAACTT ATAGTTCAGT TTTTGGAACA GGCTTCCAAA 
CCTTCAGTTA ATGAACAAAA CCAAGTTCAA CCTCCGCCTG ATAACAAGAG AAATCGTATT 
TTAAAACTAC TTGCTCTTAA AGTTGCTGCA CATTTGAAGT GGGACTTAGA CATATTAGAG 
AAAAGTTTGT CTGTTCCAGT ATTGAATATG CTACTAAATG AACTACTCTG CATCAGTAAA 
GTTCCTCCTG GGACAAAGCA TGTAGACATG GATCTGGCCA CTTTACCTCC GACCACTGCC 
ATGGCTGTAC TTCTCTATAA TAGATGGGCA ATTAGGACAA TTGTTCAAAG TAGTTTTCCA 
GTCAAACAGG CAAAACCCGG ACCCCCTCAG TTAAGTGTTA TGAATCAAAT GCAACAGGAA 
AAAGAGCTAA CAGAAAACAT TTTGAAAGTG CTCAAAGAAC AAGCTGCTGA TTCTATTTTG 
GTACTAGAAG CAGCCCTAAA ATTAAACAAG GATCTTTATG TCCATACGAT GAGAACTCTA 
GATTTATTGG CCATGGAACC AGGCATGGTA AATGGAGAAA CTGAGAGTTC TACTGCTGGA 
TTGAAAGTCA AAACCGAAGA AATGCAGTGC CAGGTGTGCT ATGATTTGGG CGCAGCATAC 
TTCCAGCAAG GCTCCACAAA TTCAGCTGTC TATGAAAATG CCAGGGAAAA ATTTTTTAGA 
ACCAAAGAAC TAATTGCAGA GATAGGTTCA TTATCTCTTC ATTGTACCAT AGATGAGAAG 
CGGTTAGCTG GCTATTGTCA AGCATGTGAT GTTCTTGTAC CTTCTTCTGA TAGTACATCT 
CAACAGTTGA CTCCATATAG TCAAGTCCAT ATTTGTTTGA GATCTGGCAA CTATCAGGAG 
GTAATACAGA TTTTCATTGA AGACAACTTA ACCTTGAGTT TACCTGTCCA GTTCCGACAG 
TCAGTCCTAA GAGAACTCTT TAAGAAAGCT CAACAGGGAA ATGAAGCTCT AGATGAAATC 
TGTTTTAAAG TTTGTGCCTG TAATACAGTC CGTGATATAC TGGAAGGCAG AACAATTAGT 
GTTCAATTTA ACCAGCTATT TCTTAGACCA AATAAAGAGA AAATAGACTT TCTTCTTGAG 
GTATGTTCAA GATCAGTAAA TTTAGAAAAA GCTTCAGAGT CTTTGAAAGG AAACATGGCT 
GCTTTTCTAA AGAATGTGTG TCTGGGGTTG GAAGATCTGC AGTATGTTTT CATGATTTCT 
TCACATGAGC TTTTCATTAC ATTGTTGAAA GATGAAGAAC GAAAGCTACT TGTTGATCAG 
ATGAGGAAGA GATCCCCTAG AGTAAATCTG TGCATTAAAC CTGTAACTTC ATTTTATGAT 
ATCCCAGCTT CAGCAAGTGT CAACATTGGT CAGTTAGAGC ATCAACTTAT ATTGTCAGTG 
GATCCTTGGA GGATTAGACA AATTTTAATT GAATTACATG GTATGACTTC AGAGCGCCAG 
TTCTGGACAG TGTCTAATAA GTGGGAAGTA CCTTCTGTCT ATAGTGGTGT TATCCTGGGA 
ATTAAAGACA ATTTAACAAG AGATTTGGTT TATATTCTTA TGGCCAAAGG TTTGCACTGC 
AGTACTGTTA AGGACTTTTC CCATGCTAAA CAGCTCTTTG CTGCTTGTTT GGAGTTGGTA 
ACAGAGTTCT CACCGAAGCT TCGTCAGGTC ATGCTGAATG AGATGTTGCT TTTGGATATT 
CATACACACG AAGCTGGGAC AGGGCAGGCA GGAGAGAGAC CGCCATCCGA CCTTATAAGT 
AGAGTACGAG GCTATCTGGA AATGAGGCTT CCTGATATTC CTCTTCGTCA AGTTATAGCT 
GAGGAATGTG TTGCCTTTAT GTTAAACTGG AGAGAAAATG AATACCTTAC ACTCCAAGTT 
CCTGCATTTT TGCTTCAGAG TAATCCATAT GTAAAGGAAC CACTCGTTTT GACTATTATT 
TTATCACTCT TTGTGAAACT TCACAATGTT CGGGAGGACA TTGTGAATGA TATTACAGCT 
GAACACATTT CTATTTGGCC ATCTTCCATT CCCAACCTCC AGTCTGTGGA CTTTGAAGCT 
GTGGCAATCA CAGTGAAAGA GCTAGTTCGA TATACACTCA GTATAAATCC AAATAACCAT 
TCTTGGTTAA TTATCCAGGC AGATATTTAC TTTGCAACGA ATCAGTATTC AGCAGCTCTT 
CACTATTACC TCCAGGCAGG AGCTGTGTGT TCTGACTTCT TTAACAAGGC TGTGCCCCCT 
GATGTTTATA CAGACCAGGT AATAAAACGA ATGATAAAAT GTTGTTCTTT GCTGAATTGC 
CACACACAGG TGGCCATTTT ATGTCAGTTC CTCAGAGAAA TTGACTACAA AACAGCGTTT 
AAATCTCTGC AAGAACAAAA CAGTCATGAT GCTATGGACT CCTACTACGA CTACATATGG 
GATGTTACCA TTTTGGAATA CTTGACTTAT CTTCATCATA AAAGAGGAGA AACAGATAAA 
AGACAAATTG CAATCAAAGC CATCGGCCAG ACAGAGTTGA ATGCAAGCAA TCCAGAAGAA 
GTGTTACAGC TGGCAGCGCA GAGAAGGAAA AAAAAGTTTC TCCAAGCAAT GGCAAAACTT 
TACTTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016869106.1
CDS	143..2911
Translation	MSAEAADREAATSSRPCTPPQTCWFEFLLEESLLEKHLRKPCPDPAPVQLIVQFLEQASKPSVNEQNQVQPPPDNKRNRILKLLALKVAAHLKWDLDILEKSLSVPVLNMLLNELLCISKVPPGTKHVDMDLATLPPTTAMAVLLYNRWAIRTIVQSSFPVKQAKPGPPQLSVMNQMQQEKELTENILKVLKEQAADSILVLEAALKLNKDLYVHTMRTLDLLAMEPGMVNGETESSTAGLKVKTEEMQCQVCYDLGAAYFQQGSTNSAVYENAREKFFRTKELIAEIGSLSLHCTIDEKRLAGYCQACDVLVPSSDSTSQQLTPYSQVHICLRSGNYQEVIQIFIEDNLTLSLPVQFRQSVLRELFKKAQQGNEALDEICFKVCACNTVRDILEGRTISVQFNQLFLRPNKEKIDFLLEVCSRSVNLEKASESLKGNMAAFLKNVCLGLEDLQYVFMISSHELFITLLKDEERKLLVDQMRKRSPRVNLCIKPVTSFYDIPASASVNIGQLEHQLILSVDPWRIRQILIELHGMTSERQFWTVSNKWEVPSVYSGVILGIKDNLTRDLVYILMAKGLHCSTVKDFSHAKQLFAACLELVTEFSPKLRQVMLNEMLLLDIHTHEAGTGQAGERPPSDLISRVRGYLEMRLPDIPLRQVIAEECVAFMLNWRENEYLTLQVPAFLLQSNPYVKEPLVLTIILSLFVKLHNVREDIVNDITAEHISIWPSSIPNLQSVDFEAVAITVKELVRYTLSINPNNHSWLIIQADIYFATNQYSAALHYYLQAGAVCSDFFNKAVPPDVYTDQVIKRMIKCCSLLNCHTQVAILCQFLREIDYKTAFKSLQEQNSHDAMDSYYDYIWDVTILEYLTYLHHKRGETDKRQIAIKAIGQTELNASNPEEVLQLAAQRRKKKFLQAMAKLYF

Target ORF information:

RefSeq Version	XM_017013617.1
Organism	Homo sapiens(human)
Definition	Homo sapiens integrator complex subunit 8 (INTS8), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017013617.1

ORF Insert Sequence:

ATGAGCGCGG AGGCGGCGGA CCGGGAGGCG GCCACCTCCA GCCGGCCCTG CACCCCGCCG 
CAGACCTGCT GGTTTGAGTT TCTGCTGGAG GAGTCACTGT TGGAGAAACA TCTGCGCAAG 
CCCTGCCCGG ATCCTGCACC AGTTCAACTT ATAGTTCAGT TTTTGGAACA GGCTTCCAAA 
CCTTCAGTTA ATGAACAAAA CCAAGTTCAA CCTCCGCCTG ATAACAAGAG AAATCGTATT 
TTAAAACTAC TTGCTCTTAA AGTTGCTGCA CATTTGAAGT GGGACTTAGA CATATTAGAG 
AAAAGTTTGT CTGTTCCAGT ATTGAATATG CTACTAAATG AACTACTCTG CATCAGTAAA 
GTTCCTCCTG GGACAAAGCA TGTAGACATG GATCTGGCCA CTTTACCTCC GACCACTGCC 
ATGGCTGTAC TTCTCTATAA TAGATGGGCA ATTAGGACAA TTGTTCAAAG TAGTTTTCCA 
GTCAAACAGG CAAAACCCGG ACCCCCTCAG TTAAGTGTTA TGAATCAAAT GCAACAGGAA 
AAAGAGCTAA CAGAAAACAT TTTGAAAGTG CTCAAAGAAC AAGCTGCTGA TTCTATTTTG 
GTACTAGAAG CAGCCCTAAA ATTAAACAAG GATCTTTATG TCCATACGAT GAGAACTCTA 
GATTTATTGG CCATGGAACC AGGCATGGTA AATGGAGAAA CTGAGAGTTC TACTGCTGGA 
TTGAAAGTCA AAACCGAAGA AATGCAGTGC CAGGTGTGCT ATGATTTGGG CGCAGCATAC 
TTCCAGCAAG GCTCCACAAA TTCAGCTGTC TATGAAAATG CCAGGGAAAA ATTTTTTAGA 
ACCAAAGAAC TAATTGCAGA GATAGGTTCA TTATCTCTTC ATTGTACCAT AGATGAGAAG 
CGGTTAGCTG GCTATTGTCA AGCATGTGAT GTTCTTGTAC CTTCTTCTGA TAGTACATCT 
CAACAGTTGA CTCCATATAG TCAAGTCCAT ATTTGTTTGA GATCTGGCAA CTATCAGGAG 
GTAATACAGA TTTTCATTGA AGACAACTTA ACCTTGAGTT TACCTGTCCA GTTCCGACAG 
TCAGTCCTAA GAGAACTCTT TAAGAAAGCT CAACAGGGAA ATGAAGCTCT AGATGAAATC 
TGTTTTAAAG TTTGTGCCTG TAATACAGTC CGTGATATAC TGGAAGGCAG AACAATTAGT 
GTTCAATTTA ACCAGCTATT TCTTAGACCA AATAAAGAGA AAATAGACTT TCTTCTTGAG 
GTATGTTCAA GATCAGTAAA TTTAGAAAAA GCTTCAGAGT CTTTGAAAGG AAACATGGCT 
GCTTTTCTAA AGAATGTGTG TCTGGGGTTG GAAGATCTGC AGTATGTTTT CATGATTTCT 
TCACATGAGC TTTTCATTAC ATTGTTGAAA GATGAAGAAC GAAAGCTACT TGTTGATCAG 
ATGAGGAAGA GATCCCCTAG AGTAAATCTG TGCATTAAAC CTGTAACTTC ATTTTATGAT 
ATCCCAGCTT CAGCAAGTGT CAACATTGGT CAGTTAGAGC ATCAACTTAT ATTGTCAGTG 
GATCCTTGGA GGATTAGACA AATTTTAATT GAATTACATG GTATGACTTC AGAGCGCCAG 
TTCTGGACAG TGTCTAATAA GTGGGAAGTA CCTTCTGTCT ATAGTGGTGT TATCCTGGGA 
ATTAAAGACA ATTTAACAAG AGATTTGGTT TATATTCTTA TGGCCAAAGG TTTGCACTGC 
AGTACTGTTA AGGACTTTTC CCATGCTAAA CAGCTCTTTG CTGCTTGTTT GGAGTTGGTA 
ACAGAGTTCT CACCGAAGCT TCGTCAGGTC ATGCTGAATG AGATGTTGCT TTTGGATATT 
CATACACACG AAGCTGGGAC AGGGCAGGCA GGAGAGAGAC CGCCATCCGA CCTTATAAGT 
AGAGTACGAG GCTATCTGGA AATGAGGCTT CCTGATATTC CTCTTCGTCA AGTTATAGCT 
GAGGAATGTG TTGCCTTTAT GTTAAACTGG AGAGAAAATG AATACCTTAC ACTCCAAGTT 
CCTGCATTTT TGCTTCAGAG TAATCCATAT GTAAAGGAAC CACTCGTTTT GACTATTATT 
TTATCACTCT TTGTGAAACT TCACAATGTT CGGGAGGACA TTGTGAATGA TATTACAGCT 
GAACACATTT CTATTTGGCC ATCTTCCATT CCCAACCTCC AGTCTGTGGA CTTTGAAGCT 
GTGGCAATCA CAGTGAAAGA GCTAGTTCGA TATACACTCA GTATAAATCC AAATAACCAT 
TCTTGGTTAA TTATCCAGGC AGATATTTAC TTTGCAACGA ATCAGTATTC AGCAGCTCTT 
CACTATTACC TCCAGGCAGG AGCTGTGTGT TCTGACTTCT TTAACAAGGC TGTGCCCCCT 
GATGTTTATA CAGACCAGGT AATAAAACGA ATGATAAAAT GTTGTTCTTT GCTGAATTGC 
CACACACAGG TGGCCATTTT ATGTCAGTTC CTCAGAGAAA TTGACTACAA AACAGCGTTT 
AAATCTCTGC AAGAACAAAA CAGTCATGAT GCTATGGACT CCTACTACGA CTACATATGG 
GATGTTACCA TTTTGGAATA CTTGACTTAT CTTCATCATA AAAGAGGAGA AACAGATAAA 
AGACAAATTG CAATCAAAGC CATCGGCCAG ACAGAGTTGA ATGCAAGCAA TCCAGAAGAA 
GTGTTACAGC TGGCAGCGCA GAGAAGGAAA AAAAAGTTTC TCCAAGCAAT GGCAAAACTT 
TACTTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

INTS8 ( XM_017013618.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016869107.1 Homo sapiens integrator complex subunit 8 (INTS8), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu98096
Clone ID Related Accession (Same CDS sequence)	XM_017013618.1
Accession Version	XM_017013618.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2397bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	integrator complex subunit 8 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000008.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTACTAA ATGAACTACT CTGCATCAGT AAAGTTCCTC CTGGGACAAA GCATGTAGAC 
ATGGATCTGG CCACTTTACC TCCGACCACT GCCATGGCTG TACTTCTCTA TAATAGATGG 
GCAATTAGGA CAATTGTTCA AAGTAGTTTT CCAGTCAAAC AGGCAAAACC CGGACCCCCT 
CAGTTAAGTG TTATGAATCA AATGCAACAG GAAAAAGAGC TAACAGAAAA CATTTTGAAA 
GTGCTCAAAG AACAAGCTGC TGATTCTATT TTGGTACTAG AAGCAGCCCT AAAATTAAAC 
AAGGATCTTT ATGTCCATAC GATGAGAACT CTAGATTTAT TGGCCATGGA ACCAGGCATG 
GTAAATGGAG AAACTGAGAG TTCTACTGCT GGATTGAAAG TCAAAACCGA AGAAATGCAG 
TGCCAGGAGG TAATACAGAT TTTCATTGAA GACAACTTAA CCTTGAGTTT ACCTGTCCAG 
TTCCGACAGT CAGTCCTAAG AGAACTCTTT AAGAAAGCTC AACAGGGAAA TGAAGCTCTA 
GATGAAATCT GTTTTAAAGT TTGTGCCTGT AATACAGTCC GTGATATACT GGAAGGCAGA 
ACAATTAGTG TTCAATTTAA CCAGCTATTT CTTAGACCAA ATAAAGAGAA AATAGACTTT 
CTTCTTGAGG TATGTTCAAG ATCAGTAAAT TTAGAAAAAG CTTCAGAGTC TTTGAAAGGA 
AACATGGCTG CTTTTCTAAA GAATGTGTGT CTGGGGTTGG AAGATCTGCA GTATGTTTTC 
ATGATTTCTT CACATGAGCT TTTCATTACA TTGTTGAAAG ATGAAGAACG AAAGCTACTT 
GTTGATCAGA TGAGGAAGAG ATCCCCTAGA GTAAATCTGT GCATTAAACC TGTAACTTCA 
TTTTATGATA TCCCAGCTTC AGCAAGTGTC AACATTGGTC AGTTAGAGCA TCAACTTATA 
TTGTCAGTGG ATCCTTGGAG GATTAGACAA ATTTTAATTG AATTACATGG TATGACTTCA 
GAGCGCCAGT TCTGGACAGT GTCTAATAAG TGGGAAGTAC CTTCTGTCTA TAGTGGTGTT 
ATCCTGGGAA TTAAAGACAA TTTAACAAGA GATTTGGTTT ATATTCTTAT GGCCAAAGGT 
TTGCACTGCA GTACTGTTAA GGACTTTTCC CATGCTAAAC AGCTCTTTGC TGCTTGTTTG 
GAGTTGGTAA CAGAGTTCTC ACCGAAGCTT CGTCAGGTCA TGCTGAATGA GATGTTGCTT 
TTGGATATTC ATACACACGA AGCTGGGACA GGGCAGGCAG GAGAGAGACC GCCATCCGAC 
CTTATAAGTA GAGTACGAGG CTATCTGGAA ATGAGGCTTC CTGATATTCC TCTTCGTCAA 
GTTATAGCTG AGGAATGTGT TGCCTTTATG TTAAACTGGA GAGAAAATGA ATACCTTACA 
CTCCAAGTTC CTGCATTTTT GCTTCAGAGT AATCCATATG TAAAGCTTGG ACAGCTTTTA 
GCAGCTACAT GCAAAGAACT TCCAGGCCCT AAAGAAAGTA GACGGACTGC CAAAGACCTT 
TGGGAAGTTG TTGTTCAAAT CTGTAGTGTG TCCAGTCAGC ACAAACGAGG AAATGATGGC 
AGAGTTAGTT TAATAAAACA GAGGGAATCT ACGTTAGGTA TCATGTATCG GAGTGAACTG 
CTTTCTTTTA TCAAAAAATT ACGAGAACCA CTCGTTTTGA CTATTATTTT ATCACTCTTT 
GTGAAACTTC ACAATGTTCG GGAGGACATT GTGAATGATA TTACAGCTGA ACACATTTCT 
ATTTGGCCAT CTTCCATTCC CAACCTCCAG TCTGTGGACT TTGAAGCTGT GGCAATCACA 
GTGAAAGAGC TAGTTCGATA TACACTCAGT ATAAATCCAA ATAACCATTC TTGGTTAATT 
ATCCAGGCAG ATATTTACTT TGCAACGAAT CAGTATTCAG CAGCTCTTCA CTATTACCTC 
CAGGCAGGAG CTGTGTGTTC TGACTTCTTT AACAAGGCTG TGCCCCCTGA TGTTTATACA 
GACCAGGTAA TAAAACGAAT GATAAAATGT TGTTCTTTGC TGAATTGCCA CACACAGGTG 
GCCATTTTAT GTCAGTTCCT CAGAGAAATT GACTACAAAA CAGCGTTTAA ATCTCTGCAA 
GAACAAAACA GTCATGATGC TATGGACTCC TACTACGACT ACATATGGGA TGTTACCATT 
TTGGAATACT TGACTTATCT TCATCATAAA AGAGGAGAAA CAGATAAAAG ACAAATTGCA 
ATCAAAGCCA TCGGCCAGAC AGAGTTGAAT GCAAGCAATC CAGAAGAAGT GTTACAGCTG 
GCAGCGCAGA GAAGGAAAAA AAAGTTTCTC CAAGCAATGG CAAAACTTTA CTTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016869107.1
CDS	287..2683
Translation	MLLNELLCISKVPPGTKHVDMDLATLPPTTAMAVLLYNRWAIRTIVQSSFPVKQAKPGPPQLSVMNQMQQEKELTENILKVLKEQAADSILVLEAALKLNKDLYVHTMRTLDLLAMEPGMVNGETESSTAGLKVKTEEMQCQEVIQIFIEDNLTLSLPVQFRQSVLRELFKKAQQGNEALDEICFKVCACNTVRDILEGRTISVQFNQLFLRPNKEKIDFLLEVCSRSVNLEKASESLKGNMAAFLKNVCLGLEDLQYVFMISSHELFITLLKDEERKLLVDQMRKRSPRVNLCIKPVTSFYDIPASASVNIGQLEHQLILSVDPWRIRQILIELHGMTSERQFWTVSNKWEVPSVYSGVILGIKDNLTRDLVYILMAKGLHCSTVKDFSHAKQLFAACLELVTEFSPKLRQVMLNEMLLLDIHTHEAGTGQAGERPPSDLISRVRGYLEMRLPDIPLRQVIAEECVAFMLNWRENEYLTLQVPAFLLQSNPYVKLGQLLAATCKELPGPKESRRTAKDLWEVVVQICSVSSQHKRGNDGRVSLIKQRESTLGIMYRSELLSFIKKLREPLVLTIILSLFVKLHNVREDIVNDITAEHISIWPSSIPNLQSVDFEAVAITVKELVRYTLSINPNNHSWLIIQADIYFATNQYSAALHYYLQAGAVCSDFFNKAVPPDVYTDQVIKRMIKCCSLLNCHTQVAILCQFLREIDYKTAFKSLQEQNSHDAMDSYYDYIWDVTILEYLTYLHHKRGETDKRQIAIKAIGQTELNASNPEEVLQLAAQRRKKKFLQAMAKLYF

Target ORF information:

RefSeq Version	XM_017013618.1
Organism	Homo sapiens(human)
Definition	Homo sapiens integrator complex subunit 8 (INTS8), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017013618.1

ORF Insert Sequence:

ATGCTACTAA ATGAACTACT CTGCATCAGT AAAGTTCCTC CTGGGACAAA GCATGTAGAC 
ATGGATCTGG CCACTTTACC TCCGACCACT GCCATGGCTG TACTTCTCTA TAATAGATGG 
GCAATTAGGA CAATTGTTCA AAGTAGTTTT CCAGTCAAAC AGGCAAAACC CGGACCCCCT 
CAGTTAAGTG TTATGAATCA AATGCAACAG GAAAAAGAGC TAACAGAAAA CATTTTGAAA 
GTGCTCAAAG AACAAGCTGC TGATTCTATT TTGGTACTAG AAGCAGCCCT AAAATTAAAC 
AAGGATCTTT ATGTCCATAC GATGAGAACT CTAGATTTAT TGGCCATGGA ACCAGGCATG 
GTAAATGGAG AAACTGAGAG TTCTACTGCT GGATTGAAAG TCAAAACCGA AGAAATGCAG 
TGCCAGGAGG TAATACAGAT TTTCATTGAA GACAACTTAA CCTTGAGTTT ACCTGTCCAG 
TTCCGACAGT CAGTCCTAAG AGAACTCTTT AAGAAAGCTC AACAGGGAAA TGAAGCTCTA 
GATGAAATCT GTTTTAAAGT TTGTGCCTGT AATACAGTCC GTGATATACT GGAAGGCAGA 
ACAATTAGTG TTCAATTTAA CCAGCTATTT CTTAGACCAA ATAAAGAGAA AATAGACTTT 
CTTCTTGAGG TATGTTCAAG ATCAGTAAAT TTAGAAAAAG CTTCAGAGTC TTTGAAAGGA 
AACATGGCTG CTTTTCTAAA GAATGTGTGT CTGGGGTTGG AAGATCTGCA GTATGTTTTC 
ATGATTTCTT CACATGAGCT TTTCATTACA TTGTTGAAAG ATGAAGAACG AAAGCTACTT 
GTTGATCAGA TGAGGAAGAG ATCCCCTAGA GTAAATCTGT GCATTAAACC TGTAACTTCA 
TTTTATGATA TCCCAGCTTC AGCAAGTGTC AACATTGGTC AGTTAGAGCA TCAACTTATA 
TTGTCAGTGG ATCCTTGGAG GATTAGACAA ATTTTAATTG AATTACATGG TATGACTTCA 
GAGCGCCAGT TCTGGACAGT GTCTAATAAG TGGGAAGTAC CTTCTGTCTA TAGTGGTGTT 
ATCCTGGGAA TTAAAGACAA TTTAACAAGA GATTTGGTTT ATATTCTTAT GGCCAAAGGT 
TTGCACTGCA GTACTGTTAA GGACTTTTCC CATGCTAAAC AGCTCTTTGC TGCTTGTTTG 
GAGTTGGTAA CAGAGTTCTC ACCGAAGCTT CGTCAGGTCA TGCTGAATGA GATGTTGCTT 
TTGGATATTC ATACACACGA AGCTGGGACA GGGCAGGCAG GAGAGAGACC GCCATCCGAC 
CTTATAAGTA GAGTACGAGG CTATCTGGAA ATGAGGCTTC CTGATATTCC TCTTCGTCAA 
GTTATAGCTG AGGAATGTGT TGCCTTTATG TTAAACTGGA GAGAAAATGA ATACCTTACA 
CTCCAAGTTC CTGCATTTTT GCTTCAGAGT AATCCATATG TAAAGCTTGG ACAGCTTTTA 
GCAGCTACAT GCAAAGAACT TCCAGGCCCT AAAGAAAGTA GACGGACTGC CAAAGACCTT 
TGGGAAGTTG TTGTTCAAAT CTGTAGTGTG TCCAGTCAGC ACAAACGAGG AAATGATGGC 
AGAGTTAGTT TAATAAAACA GAGGGAATCT ACGTTAGGTA TCATGTATCG GAGTGAACTG 
CTTTCTTTTA TCAAAAAATT ACGAGAACCA CTCGTTTTGA CTATTATTTT ATCACTCTTT 
GTGAAACTTC ACAATGTTCG GGAGGACATT GTGAATGATA TTACAGCTGA ACACATTTCT 
ATTTGGCCAT CTTCCATTCC CAACCTCCAG TCTGTGGACT TTGAAGCTGT GGCAATCACA 
GTGAAAGAGC TAGTTCGATA TACACTCAGT ATAAATCCAA ATAACCATTC TTGGTTAATT 
ATCCAGGCAG ATATTTACTT TGCAACGAAT CAGTATTCAG CAGCTCTTCA CTATTACCTC 
CAGGCAGGAG CTGTGTGTTC TGACTTCTTT AACAAGGCTG TGCCCCCTGA TGTTTATACA 
GACCAGGTAA TAAAACGAAT GATAAAATGT TGTTCTTTGC TGAATTGCCA CACACAGGTG 
GCCATTTTAT GTCAGTTCCT CAGAGAAATT GACTACAAAA CAGCGTTTAA ATCTCTGCAA 
GAACAAAACA GTCATGATGC TATGGACTCC TACTACGACT ACATATGGGA TGTTACCATT 
TTGGAATACT TGACTTATCT TCATCATAAA AGAGGAGAAA CAGATAAAAG ACAAATTGCA 
ATCAAAGCCA TCGGCCAGAC AGAGTTGAAT GCAAGCAATC CAGAAGAAGT GTTACAGCTG 
GCAGCGCAGA GAAGGAAAAA AAAGTTTCTC CAAGCAATGG CAAAACTTTA CTTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Human mutations in integrator complex subunits link transcriptome integrity to brain development.
PLoS genetics13(5)e1006809(2017 May)
Oegema R,Baillat D,Schot R,van Unen LM,Brooks A,Kia SK,Hoogeboom AJM,Xia Z,Li W,Cesaroni M,Lequin MH,van Slegtenhorst M,Dobyns WB,de Coo IFM,Verheijen FW,Kremer A,van der Spek PJ,Heijsman D,Wagner EJ,Fornerod M,Mancini GMS

Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes.
PLoS genetics10(8)e1004517(2014 Aug)
Ng MC,Shriner D,Chen BH,Li J,Chen WM,Guo X,Liu J,Bielinski SJ,Yanek LR,Nalls MA,Comeau ME,Rasmussen-Torvik LJ,Jensen RA,Evans DS,Sun YV,An P,Patel SR,Lu Y,Long J,Armstrong LL,Wagenknecht L,Yang L,Snively BM,Palmer ND,Mudgal P,Langefeld CD,Keene KL,Freedman BI,Mychaleckyj JC,Nayak U,Raffel LJ,Goodarzi MO,Chen YD,Taylor HA Jr,Correa A,Sims M,Couper D,Pankow JS,Boerwinkle E,Adeyemo A,Doumatey A,Chen G,Mathias RA,Vaidya D,Singleton AB,Zonderman AB,Igo RP Jr,Sedor JR,,Kabagambe EK,Siscovick DS,McKnight B,Rice K,Liu Y,Hsueh WC,Zhao W,Bielak LF,Kraja A,Province MA,Bottinger EP,Gottesman O,Cai Q,Zheng W,Blot WJ,Lowe WL,Pacheco JA,Crawford DC,,,Grundberg E,,Rich SS,Hayes MG,Shu XO,Loos RJ,Borecki IB,Peyser PA,Cummings SR,Psaty BM,Fornage M,Iyengar SK,Evans MK,Becker DM,Kao WH,Wilson JG,Rotter JI,Sale MM,Liu S,Rotimi CN,Bowden DW,

Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II.
Cell123(2)265-76(2005 Oct)
Baillat D,Hakimi MA,N??r AM,Shilatifard A,Cooch N,Shiekhattar R

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INTS8 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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