THUMPD1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	THUMPD1
Entrez Gene ID	55623
Full Name	THUMP domain containing 1
Synonyms	Tan1
General protein information	Preferred Names THUMP domain containing 1 Names THUMP domain-containing protein 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 16 Map Location: 16p12.3
Disorder MIM:	616662

mRNA and Protein(s)

mRNA	Protein	Name
XM_017023433.1	XP_016878922.1	THUMP domain-containing protein 1 isoform X1
NM_001304550.1	NP_001291479.1	THUMP domain-containing protein 1
NM_017736.5	NP_060206.2	THUMP domain-containing protein 1
NM_017736.4	NP_060206.2	THUMP domain-containing protein 1
XM_011545891.1	XP_011544193.1	THUMP domain-containing protein 1 isoform X2
XM_017023433.2	XP_016878922.1	THUMP domain-containing protein 1 isoform X1
NM_001304550.2	NP_001291479.1	THUMP domain-containing protein 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	THUMPD1	NP_060206.2
Bos taurus (cattle)	THUMPD1	NP_001039742.1
Rattus norvegicus (Norway rat)	Thumpd1	NP_001009688.1
Gallus gallus (chicken)	THUMPD1	XP_424600.1
Mus musculus (house mouse)	Thumpd1	NP_663560.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP007705	XP_308171.3
	THUMPD1	XP_001089980.1
Canis lupus familiaris (dog)	THUMPD1	XP_547104.2
Danio rerio (zebrafish)	thumpd1	NP_991220.1
Pan troglodytes (chimpanzee)	THUMPD1	XP_510866.4
Drosophila melanogaster (fruit fly)	CG15014	NP_647892.1
Xenopus tropicalis (tropical clawed frog)	thumpd1	NP_989059.1

Gene Ontology
Bibliography

Related articles in PubMed

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

Cytosolic THUMPD1 promotes breast cancer cells invasion and metastasis via the AKT-GSK3-Snail pathway.
Zhang X, Jiang G, Sun M, Zhou H, Miao Y, Liang M, Wang E, Zhang Y
Oncotarget8(8)13357-13366(2017 Feb)

Yeast Kre33 and human NAT10 are conserved 18S rRNA cytosine acetyltransferases that modify tRNAs assisted by the adaptor Tan1/THUMPD1.
Sharma S, Langhendries JL, Watzinger P, K?tter P, Entian KD, Lafontaine DL
Nucleic acids research43(4)2242-58(2015 Feb)

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J, Hentze MW
Cell149(6)1393-406(2012 Jun)

Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q.
Loftus BJ, Kim UJ, Sneddon VP, Kalush F, Brandon R, Fuhrmann J, Mason T, Crosby ML, Barnstead M, Cronin L, Deslattes Mays A, Cao Y, Xu RX, Kang HL, Mitchell S, Eichler EE, Harris PC, Venter JC, Adams MD
Genomics60(3)295-308(1999 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These results indicate that THUMPD1 promotes breast cancer cells invasion and migration via the AKT-GSK3beta-Snail pathway
Title: Cytosolic THUMPD1 promotes breast cancer cells invasion and metastasis via the AKT-GSK3-Snail pathway.

The following THUMPD1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the THUMPD1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu02894	NM_001304550.2 Latest version!	Homo sapiens THUMP domain containing 1 (THUMPD1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu02894	NM_017736.5 Latest version!	Homo sapiens THUMP domain containing 1 (THUMPD1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu02894	XM_017023433.2 Latest version!	Homo sapiens THUMP domain containing 1 (THUMPD1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu69542	XM_011545891.1 Latest version!	Homo sapiens THUMP domain containing 1 (THUMPD1), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
View Old Accession Versions >>
OHu02894	NM_017736.4	Homo sapiens THUMP domain containing 1 (THUMPD1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu02894	XM_017023433.1	Homo sapiens THUMP domain containing 1 (THUMPD1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu02894	NM_001304550.1	Homo sapiens THUMP domain containing 1 (THUMPD1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

THUMPD1 ( NM_001304550.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001291479.1 Homo sapiens THUMP domain containing 1 (THUMPD1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu02894
Clone ID Related Accession (Same CDS sequence)	XM_017023433.1 , NM_001304550.1 , NM_017736.5 , NM_017736.4 , XM_017023433.2 , NM_001304550.2
Accession Version	NM_001304550.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1062bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-25
Organism	Homo sapiens(human)
Product	THUMP domain-containing protein 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BX640898.1, BC000448.2 and AC004381.1. On Jan 31, 2015 this sequence version replaced XM_005255422.2. Transcript Variant: This variant (2) differs in the 3' UTR compared to variant 1. Variants 1 and 2 both encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BX640898.1, SRR1660809.136139.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCCC CTGCCCAGCA GACTACTCAG CCTGGCGGCG GGAAGCGCAA AGGCAAGGCT 
CAGTATGTGC TGGCCAAGCG CGCTCGGCGC TGCGACGCTG GCGGGCCCCG TCAGCTAGAG 
CCCGGGCTAC AGGGCATCCT CATCACCTGC AATATGAACG AGCGCAAGTG CGTGGAGGAG 
GCCTACAGCC TCCTCAACGA ATACGGCGAC GACATGTATG GGCCAGAAAA GTTTACAGAC 
AAGGATCAGC AGCCCTCTGG AAGTGAGGGA GAGGATGATG ATGCGGAGGC TGCCTTGAAG 
AAAGAAGTTG GTGACATTAA GGCATCTACA GAGATGAGGT TAAGAAGATT CCAGTCAGTG 
GAAAGTGGAG CAAATAACGT TGTCTTCATC AGGACACTTG GGATAGAGCC TGAGAAATTG 
GTGCATCATA TTCTCCAGGA TATGTACAAA ACCAAGAAAA AGAAGACTCG AGTTATTTTG 
CGAATGTTAC CCATCTCAGG CACATGCAAG GCTTTTTTAG AAGATATGAA AAAATATGCA 
GAAACATTTT TGGAACCCTG GTTTAAAGCT CCAAACAAAG GGACATTTCA GATTGTGTAC 
AAATCTCGAA ATAACAGTCA TGTGAATAGA GAAGAAGTTA TCAGAGAATT GGCAGGAATA 
GTGTGCACCC TCAATTCAGA AAATAAAGTG GATCTCACCA ATCCACAGTA CACAGTGGTA 
GTAGAAATCA TCAAAGCTGT CTGTTGCCTG AGTGTTGTGA AAGATTACAT GTTGTTTAGA 
AAATACAATC TCCAGGAGGT GGTGAAGAGC CCTAAGGATC CGTCACAGCT TAACTCAAAG 
CAGGGAAATG GGAAAGAAGC TAAACTGGAA TCTGCGGACA AATCAGACCA AAACAACACA 
GCAGAAGGAA AAAATAACCA GCAGGTACCA GAGAATACTG AGGAGCTGGG GCAGACAAAA 
CCAACGTCTA ATCCACAGGT GGTAAATGAG GGAGGAGCCA AACCTGAACT TGCAAGTCAA 
GCCACAGAAG GATCCAAGTC AAATGAAAAT GACTTCTCAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001291479.1
CDS	226..1287
Translation	MAAPAQQTTQPGGGKRKGKAQYVLAKRARRCDAGGPRQLEPGLQGILITCNMNERKCVEEAYSLLNEYGDDMYGPEKFTDKDQQPSGSEGEDDDAEAALKKEVGDIKASTEMRLRRFQSVESGANNVVFIRTLGIEPEKLVHHILQDMYKTKKKKTRVILRMLPISGTCKAFLEDMKKYAETFLEPWFKAPNKGTFQIVYKSRNNSHVNREEVIRELAGIVCTLNSENKVDLTNPQYTVVVEIIKAVCCLSVVKDYMLFRKYNLQEVVKSPKDPSQLNSKQGNGKEAKLESADKSDQNNTAEGKNNQQVPENTEELGQTKPTSNPQVVNEGGAKPELASQATEGSKSNENDFS

Target ORF information:

RefSeq Version	NM_001304550.1
Organism	Homo sapiens(human)
Definition	Homo sapiens THUMP domain containing 1 (THUMPD1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001304550.1

ORF Insert Sequence:

ATGGCGGCCC CTGCCCAGCA GACTACTCAG CCTGGCGGCG GGAAGCGCAA AGGCAAGGCT 
CAGTATGTGC TGGCCAAGCG CGCTCGGCGC TGCGACGCTG GCGGGCCCCG TCAGCTAGAG 
CCCGGGCTAC AGGGCATCCT CATCACCTGC AATATGAACG AGCGCAAGTG CGTGGAGGAG 
GCCTACAGCC TCCTCAACGA ATACGGCGAC GACATGTATG GGCCAGAAAA GTTTACAGAC 
AAGGATCAGC AGCCCTCTGG AAGTGAGGGA GAGGATGATG ATGCGGAGGC TGCCTTGAAG 
AAAGAAGTTG GTGACATTAA GGCATCTACA GAGATGAGGT TAAGAAGATT CCAGTCAGTG 
GAAAGTGGAG CAAATAACGT TGTCTTCATC AGGACACTTG GGATAGAGCC TGAGAAATTG 
GTGCATCATA TTCTCCAGGA TATGTACAAA ACCAAGAAAA AGAAGACTCG AGTTATTTTG 
CGAATGTTAC CCATCTCAGG CACATGCAAG GCTTTTTTAG AAGATATGAA AAAATATGCA 
GAAACATTTT TGGAACCCTG GTTTAAAGCT CCAAACAAAG GGACATTTCA GATTGTGTAC 
AAATCTCGAA ATAACAGTCA TGTGAATAGA GAAGAAGTTA TCAGAGAATT GGCAGGAATA 
GTGTGCACCC TCAATTCAGA AAATAAAGTG GATCTCACCA ATCCACAGTA CACAGTGGTA 
GTAGAAATCA TCAAAGCTGT CTGTTGCCTG AGTGTTGTGA AAGATTACAT GTTGTTTAGA 
AAATACAATC TCCAGGAGGT GGTGAAGAGC CCTAAGGATC CGTCACAGCT TAACTCAAAG 
CAGGGAAATG GGAAAGAAGC TAAACTGGAA TCTGCGGACA AATCAGACCA AAACAACACA 
GCAGAAGGAA AAAATAACCA GCAGGTACCA GAGAATACTG AGGAGCTGGG GCAGACAAAA 
CCAACGTCTA ATCCACAGGT GGTAAATGAG GGAGGAGCCA AACCTGAACT TGCAAGTCAA 
GCCACAGAAG GATCCAAGTC AAATGAAAAT GACTTCTCAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

THUMPD1 ( NM_017736.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_060206.2 Homo sapiens THUMP domain containing 1 (THUMPD1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu02894
Clone ID Related Accession (Same CDS sequence)	XM_017023433.1 , NM_001304550.1 , NM_017736.5 , NM_017736.4 , XM_017023433.2 , NM_001304550.2
Accession Version	NM_017736.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1062bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-10
Organism	Homo sapiens(human)
Product	THUMP domain-containing protein 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC004381.1. On Nov 23, 2018 this sequence version replaced NM_017736.4. Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK000281.1, SRR1660809.133661.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000396083.7/ ENSP00000379392.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGGCCC CTGCCCAGCA GACTACTCAG CCTGGCGGCG GGAAGCGCAA AGGCAAGGCT 
CAGTATGTGC TGGCCAAGCG CGCTCGGCGC TGCGACGCTG GCGGGCCCCG TCAGCTAGAG 
CCCGGGCTAC AGGGCATCCT CATCACCTGC AATATGAACG AGCGCAAGTG CGTGGAGGAG 
GCCTACAGCC TCCTCAACGA ATACGGCGAC GACATGTATG GGCCAGAAAA GTTTACAGAC 
AAGGATCAGC AGCCCTCTGG AAGTGAGGGA GAGGATGATG ATGCGGAGGC TGCCTTGAAG 
AAAGAAGTTG GTGACATTAA GGCATCTACA GAGATGAGGT TAAGAAGATT CCAGTCAGTG 
GAAAGTGGAG CAAATAACGT TGTCTTCATC AGGACACTTG GGATAGAGCC TGAGAAATTG 
GTGCATCATA TTCTCCAGGA TATGTACAAA ACCAAGAAAA AGAAGACTCG AGTTATTTTG 
CGAATGTTAC CCATCTCAGG CACATGCAAG GCTTTTTTAG AAGATATGAA AAAATATGCA 
GAAACATTTT TGGAACCCTG GTTTAAAGCT CCAAACAAAG GGACATTTCA GATTGTGTAC 
AAATCTCGAA ATAACAGTCA TGTGAATAGA GAAGAAGTTA TCAGAGAATT GGCAGGAATA 
GTGTGCACCC TCAATTCAGA AAATAAAGTG GATCTCACCA ATCCACAGTA CACAGTGGTA 
GTAGAAATCA TCAAAGCTGT CTGTTGCCTG AGTGTTGTGA AAGATTACAT GTTGTTTAGA 
AAATACAATC TCCAGGAGGT GGTGAAGAGC CCTAAGGATC CGTCACAGCT TAACTCAAAG 
CAGGGAAATG GGAAAGAAGC TAAACTGGAA TCTGCGGACA AATCAGACCA AAACAACACA 
GCAGAAGGAA AAAATAACCA GCAGGTACCA GAGAATACTG AGGAGCTGGG GCAGACAAAA 
CCAACGTCTA ATCCACAGGT GGTAAATGAG GGAGGAGCCA AACCTGAACT TGCAAGTCAA 
GCCACAGAAG GATCCAAGTC AAATGAAAAT GACTTCTCAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060206.2
CDS	80..1141
Translation	MAAPAQQTTQPGGGKRKGKAQYVLAKRARRCDAGGPRQLEPGLQGILITCNMNERKCVEEAYSLLNEYGDDMYGPEKFTDKDQQPSGSEGEDDDAEAALKKEVGDIKASTEMRLRRFQSVESGANNVVFIRTLGIEPEKLVHHILQDMYKTKKKKTRVILRMLPISGTCKAFLEDMKKYAETFLEPWFKAPNKGTFQIVYKSRNNSHVNREEVIRELAGIVCTLNSENKVDLTNPQYTVVVEIIKAVCCLSVVKDYMLFRKYNLQEVVKSPKDPSQLNSKQGNGKEAKLESADKSDQNNTAEGKNNQQVPENTEELGQTKPTSNPQVVNEGGAKPELASQATEGSKSNENDFS

Target ORF information:

RefSeq Version	NM_017736.5
Organism	Homo sapiens(human)
Definition	Homo sapiens THUMP domain containing 1 (THUMPD1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_017736.5

ORF Insert Sequence:

ATGGCGGCCC CTGCCCAGCA GACTACTCAG CCTGGCGGCG GGAAGCGCAA AGGCAAGGCT 
CAGTATGTGC TGGCCAAGCG CGCTCGGCGC TGCGACGCTG GCGGGCCCCG TCAGCTAGAG 
CCCGGGCTAC AGGGCATCCT CATCACCTGC AATATGAACG AGCGCAAGTG CGTGGAGGAG 
GCCTACAGCC TCCTCAACGA ATACGGCGAC GACATGTATG GGCCAGAAAA GTTTACAGAC 
AAGGATCAGC AGCCCTCTGG AAGTGAGGGA GAGGATGATG ATGCGGAGGC TGCCTTGAAG 
AAAGAAGTTG GTGACATTAA GGCATCTACA GAGATGAGGT TAAGAAGATT CCAGTCAGTG 
GAAAGTGGAG CAAATAACGT TGTCTTCATC AGGACACTTG GGATAGAGCC TGAGAAATTG 
GTGCATCATA TTCTCCAGGA TATGTACAAA ACCAAGAAAA AGAAGACTCG AGTTATTTTG 
CGAATGTTAC CCATCTCAGG CACATGCAAG GCTTTTTTAG AAGATATGAA AAAATATGCA 
GAAACATTTT TGGAACCCTG GTTTAAAGCT CCAAACAAAG GGACATTTCA GATTGTGTAC 
AAATCTCGAA ATAACAGTCA TGTGAATAGA GAAGAAGTTA TCAGAGAATT GGCAGGAATA 
GTGTGCACCC TCAATTCAGA AAATAAAGTG GATCTCACCA ATCCACAGTA CACAGTGGTA 
GTAGAAATCA TCAAAGCTGT CTGTTGCCTG AGTGTTGTGA AAGATTACAT GTTGTTTAGA 
AAATACAATC TCCAGGAGGT GGTGAAGAGC CCTAAGGATC CGTCACAGCT TAACTCAAAG 
CAGGGAAATG GGAAAGAAGC TAAACTGGAA TCTGCGGACA AATCAGACCA AAACAACACA 
GCAGAAGGAA AAAATAACCA GCAGGTACCA GAGAATACTG AGGAGCTGGG GCAGACAAAA 
CCAACGTCTA ATCCACAGGT GGTAAATGAG GGAGGAGCCA AACCTGAACT TGCAAGTCAA 
GCCACAGAAG GATCCAAGTC AAATGAAAAT GACTTCTCAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

THUMPD1 ( NM_017736.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_060206.2 Homo sapiens THUMP domain containing 1 (THUMPD1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu02894
Clone ID Related Accession (Same CDS sequence)	XM_017023433.1 , NM_001304550.1 , NM_017736.5 , NM_017736.4 , XM_017023433.2 , NM_001304550.2
Accession Version	NM_017736.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1062bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	THUMP domain-containing protein 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA421094.1, BC000448.2, AC004381.1 and BX640898.1. On Jan 31, 2015 this sequence version replaced NM_017736.3. Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.133661.1, SRR1803617.183570.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCCC CTGCCCAGCA GACTACTCAG CCTGGCGGCG GGAAGCGCAA AGGCAAGGCT 
CAGTATGTGC TGGCCAAGCG CGCTCGGCGC TGCGACGCTG GCGGGCCCCG TCAGCTAGAG 
CCCGGGCTAC AGGGCATCCT CATCACCTGC AATATGAACG AGCGCAAGTG CGTGGAGGAG 
GCCTACAGCC TCCTCAACGA ATACGGCGAC GACATGTATG GGCCAGAAAA GTTTACAGAC 
AAGGATCAGC AGCCCTCTGG AAGTGAGGGA GAGGATGATG ATGCGGAGGC TGCCTTGAAG 
AAAGAAGTTG GTGACATTAA GGCATCTACA GAGATGAGGT TAAGAAGATT CCAGTCAGTG 
GAAAGTGGAG CAAATAACGT TGTCTTCATC AGGACACTTG GGATAGAGCC TGAGAAATTG 
GTGCATCATA TTCTCCAGGA TATGTACAAA ACCAAGAAAA AGAAGACTCG AGTTATTTTG 
CGAATGTTAC CCATCTCAGG CACATGCAAG GCTTTTTTAG AAGATATGAA AAAATATGCA 
GAAACATTTT TGGAACCCTG GTTTAAAGCT CCAAACAAAG GGACATTTCA GATTGTGTAC 
AAATCTCGAA ATAACAGTCA TGTGAATAGA GAAGAAGTTA TCAGAGAATT GGCAGGAATA 
GTGTGCACCC TCAATTCAGA AAATAAAGTG GATCTCACCA ATCCACAGTA CACAGTGGTA 
GTAGAAATCA TCAAAGCTGT CTGTTGCCTG AGTGTTGTGA AAGATTACAT GTTGTTTAGA 
AAATACAATC TCCAGGAGGT GGTGAAGAGC CCTAAGGATC CGTCACAGCT TAACTCAAAG 
CAGGGAAATG GGAAAGAAGC TAAACTGGAA TCTGCGGACA AATCAGACCA AAACAACACA 
GCAGAAGGAA AAAATAACCA GCAGGTACCA GAGAATACTG AGGAGCTGGG GCAGACAAAA 
CCAACGTCTA ATCCACAGGT GGTAAATGAG GGAGGAGCCA AACCTGAACT TGCAAGTCAA 
GCCACAGAAG GATCCAAGTC AAATGAAAAT GACTTCTCAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060206.2
CDS	226..1287
Translation	MAAPAQQTTQPGGGKRKGKAQYVLAKRARRCDAGGPRQLEPGLQGILITCNMNERKCVEEAYSLLNEYGDDMYGPEKFTDKDQQPSGSEGEDDDAEAALKKEVGDIKASTEMRLRRFQSVESGANNVVFIRTLGIEPEKLVHHILQDMYKTKKKKTRVILRMLPISGTCKAFLEDMKKYAETFLEPWFKAPNKGTFQIVYKSRNNSHVNREEVIRELAGIVCTLNSENKVDLTNPQYTVVVEIIKAVCCLSVVKDYMLFRKYNLQEVVKSPKDPSQLNSKQGNGKEAKLESADKSDQNNTAEGKNNQQVPENTEELGQTKPTSNPQVVNEGGAKPELASQATEGSKSNENDFS

Target ORF information:

RefSeq Version	NM_017736.4
Organism	Homo sapiens(human)
Definition	Homo sapiens THUMP domain containing 1 (THUMPD1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_017736.4

ORF Insert Sequence:

ATGGCGGCCC CTGCCCAGCA GACTACTCAG CCTGGCGGCG GGAAGCGCAA AGGCAAGGCT 
CAGTATGTGC TGGCCAAGCG CGCTCGGCGC TGCGACGCTG GCGGGCCCCG TCAGCTAGAG 
CCCGGGCTAC AGGGCATCCT CATCACCTGC AATATGAACG AGCGCAAGTG CGTGGAGGAG 
GCCTACAGCC TCCTCAACGA ATACGGCGAC GACATGTATG GGCCAGAAAA GTTTACAGAC 
AAGGATCAGC AGCCCTCTGG AAGTGAGGGA GAGGATGATG ATGCGGAGGC TGCCTTGAAG 
AAAGAAGTTG GTGACATTAA GGCATCTACA GAGATGAGGT TAAGAAGATT CCAGTCAGTG 
GAAAGTGGAG CAAATAACGT TGTCTTCATC AGGACACTTG GGATAGAGCC TGAGAAATTG 
GTGCATCATA TTCTCCAGGA TATGTACAAA ACCAAGAAAA AGAAGACTCG AGTTATTTTG 
CGAATGTTAC CCATCTCAGG CACATGCAAG GCTTTTTTAG AAGATATGAA AAAATATGCA 
GAAACATTTT TGGAACCCTG GTTTAAAGCT CCAAACAAAG GGACATTTCA GATTGTGTAC 
AAATCTCGAA ATAACAGTCA TGTGAATAGA GAAGAAGTTA TCAGAGAATT GGCAGGAATA 
GTGTGCACCC TCAATTCAGA AAATAAAGTG GATCTCACCA ATCCACAGTA CACAGTGGTA 
GTAGAAATCA TCAAAGCTGT CTGTTGCCTG AGTGTTGTGA AAGATTACAT GTTGTTTAGA 
AAATACAATC TCCAGGAGGT GGTGAAGAGC CCTAAGGATC CGTCACAGCT TAACTCAAAG 
CAGGGAAATG GGAAAGAAGC TAAACTGGAA TCTGCGGACA AATCAGACCA AAACAACACA 
GCAGAAGGAA AAAATAACCA GCAGGTACCA GAGAATACTG AGGAGCTGGG GCAGACAAAA 
CCAACGTCTA ATCCACAGGT GGTAAATGAG GGAGGAGCCA AACCTGAACT TGCAAGTCAA 
GCCACAGAAG GATCCAAGTC AAATGAAAAT GACTTCTCAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

THUMPD1 ( NM_001304550.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001291479.1 Homo sapiens THUMP domain containing 1 (THUMPD1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu02894
Clone ID Related Accession (Same CDS sequence)	XM_017023433.1 , NM_001304550.1 , NM_017736.5 , NM_017736.4 , XM_017023433.2 , NM_001304550.2
Accession Version	NM_001304550.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1062bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Homo sapiens(human)
Product	THUMP domain-containing protein 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC004381.1. On May 31, 2019 this sequence version replaced NM_001304550.1. Transcript Variant: This variant (2) differs in the 3' UTR compared to variant 1. Variants 1 and 2 both encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BX640898.1, SRR1660807.131928.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCCC CTGCCCAGCA GACTACTCAG CCTGGCGGCG GGAAGCGCAA AGGCAAGGCT 
CAGTATGTGC TGGCCAAGCG CGCTCGGCGC TGCGACGCTG GCGGGCCCCG TCAGCTAGAG 
CCCGGGCTAC AGGGCATCCT CATCACCTGC AATATGAACG AGCGCAAGTG CGTGGAGGAG 
GCCTACAGCC TCCTCAACGA ATACGGCGAC GACATGTATG GGCCAGAAAA GTTTACAGAC 
AAGGATCAGC AGCCCTCTGG AAGTGAGGGA GAGGATGATG ATGCGGAGGC TGCCTTGAAG 
AAAGAAGTTG GTGACATTAA GGCATCTACA GAGATGAGGT TAAGAAGATT CCAGTCAGTG 
GAAAGTGGAG CAAATAACGT TGTCTTCATC AGGACACTTG GGATAGAGCC TGAGAAATTG 
GTGCATCATA TTCTCCAGGA TATGTACAAA ACCAAGAAAA AGAAGACTCG AGTTATTTTG 
CGAATGTTAC CCATCTCAGG CACATGCAAG GCTTTTTTAG AAGATATGAA AAAATATGCA 
GAAACATTTT TGGAACCCTG GTTTAAAGCT CCAAACAAAG GGACATTTCA GATTGTGTAC 
AAATCTCGAA ATAACAGTCA TGTGAATAGA GAAGAAGTTA TCAGAGAATT GGCAGGAATA 
GTGTGCACCC TCAATTCAGA AAATAAAGTG GATCTCACCA ATCCACAGTA CACAGTGGTA 
GTAGAAATCA TCAAAGCTGT CTGTTGCCTG AGTGTTGTGA AAGATTACAT GTTGTTTAGA 
AAATACAATC TCCAGGAGGT GGTGAAGAGC CCTAAGGATC CGTCACAGCT TAACTCAAAG 
CAGGGAAATG GGAAAGAAGC TAAACTGGAA TCTGCGGACA AATCAGACCA AAACAACACA 
GCAGAAGGAA AAAATAACCA GCAGGTACCA GAGAATACTG AGGAGCTGGG GCAGACAAAA 
CCAACGTCTA ATCCACAGGT GGTAAATGAG GGAGGAGCCA AACCTGAACT TGCAAGTCAA 
GCCACAGAAG GATCCAAGTC AAATGAAAAT GACTTCTCAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001291479.1
CDS	80..1141
Translation	MAAPAQQTTQPGGGKRKGKAQYVLAKRARRCDAGGPRQLEPGLQGILITCNMNERKCVEEAYSLLNEYGDDMYGPEKFTDKDQQPSGSEGEDDDAEAALKKEVGDIKASTEMRLRRFQSVESGANNVVFIRTLGIEPEKLVHHILQDMYKTKKKKTRVILRMLPISGTCKAFLEDMKKYAETFLEPWFKAPNKGTFQIVYKSRNNSHVNREEVIRELAGIVCTLNSENKVDLTNPQYTVVVEIIKAVCCLSVVKDYMLFRKYNLQEVVKSPKDPSQLNSKQGNGKEAKLESADKSDQNNTAEGKNNQQVPENTEELGQTKPTSNPQVVNEGGAKPELASQATEGSKSNENDFS

Target ORF information:

RefSeq Version	NM_001304550.2
Organism	Homo sapiens(human)
Definition	Homo sapiens THUMP domain containing 1 (THUMPD1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001304550.2

ORF Insert Sequence:

ATGGCGGCCC CTGCCCAGCA GACTACTCAG CCTGGCGGCG GGAAGCGCAA AGGCAAGGCT 
CAGTATGTGC TGGCCAAGCG CGCTCGGCGC TGCGACGCTG GCGGGCCCCG TCAGCTAGAG 
CCCGGGCTAC AGGGCATCCT CATCACCTGC AATATGAACG AGCGCAAGTG CGTGGAGGAG 
GCCTACAGCC TCCTCAACGA ATACGGCGAC GACATGTATG GGCCAGAAAA GTTTACAGAC 
AAGGATCAGC AGCCCTCTGG AAGTGAGGGA GAGGATGATG ATGCGGAGGC TGCCTTGAAG 
AAAGAAGTTG GTGACATTAA GGCATCTACA GAGATGAGGT TAAGAAGATT CCAGTCAGTG 
GAAAGTGGAG CAAATAACGT TGTCTTCATC AGGACACTTG GGATAGAGCC TGAGAAATTG 
GTGCATCATA TTCTCCAGGA TATGTACAAA ACCAAGAAAA AGAAGACTCG AGTTATTTTG 
CGAATGTTAC CCATCTCAGG CACATGCAAG GCTTTTTTAG AAGATATGAA AAAATATGCA 
GAAACATTTT TGGAACCCTG GTTTAAAGCT CCAAACAAAG GGACATTTCA GATTGTGTAC 
AAATCTCGAA ATAACAGTCA TGTGAATAGA GAAGAAGTTA TCAGAGAATT GGCAGGAATA 
GTGTGCACCC TCAATTCAGA AAATAAAGTG GATCTCACCA ATCCACAGTA CACAGTGGTA 
GTAGAAATCA TCAAAGCTGT CTGTTGCCTG AGTGTTGTGA AAGATTACAT GTTGTTTAGA 
AAATACAATC TCCAGGAGGT GGTGAAGAGC CCTAAGGATC CGTCACAGCT TAACTCAAAG 
CAGGGAAATG GGAAAGAAGC TAAACTGGAA TCTGCGGACA AATCAGACCA AAACAACACA 
GCAGAAGGAA AAAATAACCA GCAGGTACCA GAGAATACTG AGGAGCTGGG GCAGACAAAA 
CCAACGTCTA ATCCACAGGT GGTAAATGAG GGAGGAGCCA AACCTGAACT TGCAAGTCAA 
GCCACAGAAG GATCCAAGTC AAATGAAAAT GACTTCTCAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

THUMPD1 ( XM_017023433.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016878922.1 Homo sapiens THUMP domain containing 1 (THUMPD1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu02894
Clone ID Related Accession (Same CDS sequence)	XM_017023433.1 , NM_001304550.1 , NM_017736.5 , NM_017736.4 , XM_017023433.2 , NM_001304550.2
Accession Version	XM_017023433.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1062bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	THUMP domain-containing protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000016.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGCCC CTGCCCAGCA GACTACTCAG CCTGGCGGCG GGAAGCGCAA AGGCAAGGCT 
CAGTATGTGC TGGCCAAGCG CGCTCGGCGC TGCGACGCTG GCGGGCCCCG TCAGCTAGAG 
CCCGGGCTAC AGGGCATCCT CATCACCTGC AATATGAACG AGCGCAAGTG CGTGGAGGAG 
GCCTACAGCC TCCTCAACGA ATACGGCGAC GACATGTATG GGCCAGAAAA GTTTACAGAC 
AAGGATCAGC AGCCCTCTGG AAGTGAGGGA GAGGATGATG ATGCGGAGGC TGCCTTGAAG 
AAAGAAGTTG GTGACATTAA GGCATCTACA GAGATGAGGT TAAGAAGATT CCAGTCAGTG 
GAAAGTGGAG CAAATAACGT TGTCTTCATC AGGACACTTG GGATAGAGCC TGAGAAATTG 
GTGCATCATA TTCTCCAGGA TATGTACAAA ACCAAGAAAA AGAAGACTCG AGTTATTTTG 
CGAATGTTAC CCATCTCAGG CACATGCAAG GCTTTTTTAG AAGATATGAA AAAATATGCA 
GAAACATTTT TGGAACCCTG GTTTAAAGCT CCAAACAAAG GGACATTTCA GATTGTGTAC 
AAATCTCGAA ATAACAGTCA TGTGAATAGA GAAGAAGTTA TCAGAGAATT GGCAGGAATA 
GTGTGCACCC TCAATTCAGA AAATAAAGTG GATCTCACCA ATCCACAGTA CACAGTGGTA 
GTAGAAATCA TCAAAGCTGT CTGTTGCCTG AGTGTTGTGA AAGATTACAT GTTGTTTAGA 
AAATACAATC TCCAGGAGGT GGTGAAGAGC CCTAAGGATC CGTCACAGCT TAACTCAAAG 
CAGGGAAATG GGAAAGAAGC TAAACTGGAA TCTGCGGACA AATCAGACCA AAACAACACA 
GCAGAAGGAA AAAATAACCA GCAGGTACCA GAGAATACTG AGGAGCTGGG GCAGACAAAA 
CCAACGTCTA ATCCACAGGT GGTAAATGAG GGAGGAGCCA AACCTGAACT TGCAAGTCAA 
GCCACAGAAG GATCCAAGTC AAATGAAAAT GACTTCTCAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016878922.1
CDS	168..1229
Translation	MAAPAQQTTQPGGGKRKGKAQYVLAKRARRCDAGGPRQLEPGLQGILITCNMNERKCVEEAYSLLNEYGDDMYGPEKFTDKDQQPSGSEGEDDDAEAALKKEVGDIKASTEMRLRRFQSVESGANNVVFIRTLGIEPEKLVHHILQDMYKTKKKKTRVILRMLPISGTCKAFLEDMKKYAETFLEPWFKAPNKGTFQIVYKSRNNSHVNREEVIRELAGIVCTLNSENKVDLTNPQYTVVVEIIKAVCCLSVVKDYMLFRKYNLQEVVKSPKDPSQLNSKQGNGKEAKLESADKSDQNNTAEGKNNQQVPENTEELGQTKPTSNPQVVNEGGAKPELASQATEGSKSNENDFS

Target ORF information:

RefSeq Version	XM_017023433.1
Organism	Homo sapiens(human)
Definition	Homo sapiens THUMP domain containing 1 (THUMPD1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017023433.1

ORF Insert Sequence:

ATGGCGGCCC CTGCCCAGCA GACTACTCAG CCTGGCGGCG GGAAGCGCAA AGGCAAGGCT 
CAGTATGTGC TGGCCAAGCG CGCTCGGCGC TGCGACGCTG GCGGGCCCCG TCAGCTAGAG 
CCCGGGCTAC AGGGCATCCT CATCACCTGC AATATGAACG AGCGCAAGTG CGTGGAGGAG 
GCCTACAGCC TCCTCAACGA ATACGGCGAC GACATGTATG GGCCAGAAAA GTTTACAGAC 
AAGGATCAGC AGCCCTCTGG AAGTGAGGGA GAGGATGATG ATGCGGAGGC TGCCTTGAAG 
AAAGAAGTTG GTGACATTAA GGCATCTACA GAGATGAGGT TAAGAAGATT CCAGTCAGTG 
GAAAGTGGAG CAAATAACGT TGTCTTCATC AGGACACTTG GGATAGAGCC TGAGAAATTG 
GTGCATCATA TTCTCCAGGA TATGTACAAA ACCAAGAAAA AGAAGACTCG AGTTATTTTG 
CGAATGTTAC CCATCTCAGG CACATGCAAG GCTTTTTTAG AAGATATGAA AAAATATGCA 
GAAACATTTT TGGAACCCTG GTTTAAAGCT CCAAACAAAG GGACATTTCA GATTGTGTAC 
AAATCTCGAA ATAACAGTCA TGTGAATAGA GAAGAAGTTA TCAGAGAATT GGCAGGAATA 
GTGTGCACCC TCAATTCAGA AAATAAAGTG GATCTCACCA ATCCACAGTA CACAGTGGTA 
GTAGAAATCA TCAAAGCTGT CTGTTGCCTG AGTGTTGTGA AAGATTACAT GTTGTTTAGA 
AAATACAATC TCCAGGAGGT GGTGAAGAGC CCTAAGGATC CGTCACAGCT TAACTCAAAG 
CAGGGAAATG GGAAAGAAGC TAAACTGGAA TCTGCGGACA AATCAGACCA AAACAACACA 
GCAGAAGGAA AAAATAACCA GCAGGTACCA GAGAATACTG AGGAGCTGGG GCAGACAAAA 
CCAACGTCTA ATCCACAGGT GGTAAATGAG GGAGGAGCCA AACCTGAACT TGCAAGTCAA 
GCCACAGAAG GATCCAAGTC AAATGAAAAT GACTTCTCAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

THUMPD1 ( XM_017023433.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_016878922.1 Homo sapiens THUMP domain containing 1 (THUMPD1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu02894
Clone ID Related Accession (Same CDS sequence)	XM_017023433.1 , NM_001304550.1 , NM_017736.5 , NM_017736.4 , XM_017023433.2 , NM_001304550.2
Accession Version	XM_017023433.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1062bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	THUMP domain-containing protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000016.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017023433.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGCCC CTGCCCAGCA GACTACTCAG CCTGGCGGCG GGAAGCGCAA AGGCAAGGCT 
CAGTATGTGC TGGCCAAGCG CGCTCGGCGC TGCGACGCTG GCGGGCCCCG TCAGCTAGAG 
CCCGGGCTAC AGGGCATCCT CATCACCTGC AATATGAACG AGCGCAAGTG CGTGGAGGAG 
GCCTACAGCC TCCTCAACGA ATACGGCGAC GACATGTATG GGCCAGAAAA GTTTACAGAC 
AAGGATCAGC AGCCCTCTGG AAGTGAGGGA GAGGATGATG ATGCGGAGGC TGCCTTGAAG 
AAAGAAGTTG GTGACATTAA GGCATCTACA GAGATGAGGT TAAGAAGATT CCAGTCAGTG 
GAAAGTGGAG CAAATAACGT TGTCTTCATC AGGACACTTG GGATAGAGCC TGAGAAATTG 
GTGCATCATA TTCTCCAGGA TATGTACAAA ACCAAGAAAA AGAAGACTCG AGTTATTTTG 
CGAATGTTAC CCATCTCAGG CACATGCAAG GCTTTTTTAG AAGATATGAA AAAATATGCA 
GAAACATTTT TGGAACCCTG GTTTAAAGCT CCAAACAAAG GGACATTTCA GATTGTGTAC 
AAATCTCGAA ATAACAGTCA TGTGAATAGA GAAGAAGTTA TCAGAGAATT GGCAGGAATA 
GTGTGCACCC TCAATTCAGA AAATAAAGTG GATCTCACCA ATCCACAGTA CACAGTGGTA 
GTAGAAATCA TCAAAGCTGT CTGTTGCCTG AGTGTTGTGA AAGATTACAT GTTGTTTAGA 
AAATACAATC TCCAGGAGGT GGTGAAGAGC CCTAAGGATC CGTCACAGCT TAACTCAAAG 
CAGGGAAATG GGAAAGAAGC TAAACTGGAA TCTGCGGACA AATCAGACCA AAACAACACA 
GCAGAAGGAA AAAATAACCA GCAGGTACCA GAGAATACTG AGGAGCTGGG GCAGACAAAA 
CCAACGTCTA ATCCACAGGT GGTAAATGAG GGAGGAGCCA AACCTGAACT TGCAAGTCAA 
GCCACAGAAG GATCCAAGTC AAATGAAAAT GACTTCTCAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016878922.1
CDS	92..1153
Translation	MAAPAQQTTQPGGGKRKGKAQYVLAKRARRCDAGGPRQLEPGLQGILITCNMNERKCVEEAYSLLNEYGDDMYGPEKFTDKDQQPSGSEGEDDDAEAALKKEVGDIKASTEMRLRRFQSVESGANNVVFIRTLGIEPEKLVHHILQDMYKTKKKKTRVILRMLPISGTCKAFLEDMKKYAETFLEPWFKAPNKGTFQIVYKSRNNSHVNREEVIRELAGIVCTLNSENKVDLTNPQYTVVVEIIKAVCCLSVVKDYMLFRKYNLQEVVKSPKDPSQLNSKQGNGKEAKLESADKSDQNNTAEGKNNQQVPENTEELGQTKPTSNPQVVNEGGAKPELASQATEGSKSNENDFS

Target ORF information:

RefSeq Version	XM_017023433.2
Organism	Homo sapiens(human)
Definition	Homo sapiens THUMP domain containing 1 (THUMPD1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017023433.2

ORF Insert Sequence:

ATGGCGGCCC CTGCCCAGCA GACTACTCAG CCTGGCGGCG GGAAGCGCAA AGGCAAGGCT 
CAGTATGTGC TGGCCAAGCG CGCTCGGCGC TGCGACGCTG GCGGGCCCCG TCAGCTAGAG 
CCCGGGCTAC AGGGCATCCT CATCACCTGC AATATGAACG AGCGCAAGTG CGTGGAGGAG 
GCCTACAGCC TCCTCAACGA ATACGGCGAC GACATGTATG GGCCAGAAAA GTTTACAGAC 
AAGGATCAGC AGCCCTCTGG AAGTGAGGGA GAGGATGATG ATGCGGAGGC TGCCTTGAAG 
AAAGAAGTTG GTGACATTAA GGCATCTACA GAGATGAGGT TAAGAAGATT CCAGTCAGTG 
GAAAGTGGAG CAAATAACGT TGTCTTCATC AGGACACTTG GGATAGAGCC TGAGAAATTG 
GTGCATCATA TTCTCCAGGA TATGTACAAA ACCAAGAAAA AGAAGACTCG AGTTATTTTG 
CGAATGTTAC CCATCTCAGG CACATGCAAG GCTTTTTTAG AAGATATGAA AAAATATGCA 
GAAACATTTT TGGAACCCTG GTTTAAAGCT CCAAACAAAG GGACATTTCA GATTGTGTAC 
AAATCTCGAA ATAACAGTCA TGTGAATAGA GAAGAAGTTA TCAGAGAATT GGCAGGAATA 
GTGTGCACCC TCAATTCAGA AAATAAAGTG GATCTCACCA ATCCACAGTA CACAGTGGTA 
GTAGAAATCA TCAAAGCTGT CTGTTGCCTG AGTGTTGTGA AAGATTACAT GTTGTTTAGA 
AAATACAATC TCCAGGAGGT GGTGAAGAGC CCTAAGGATC CGTCACAGCT TAACTCAAAG 
CAGGGAAATG GGAAAGAAGC TAAACTGGAA TCTGCGGACA AATCAGACCA AAACAACACA 
GCAGAAGGAA AAAATAACCA GCAGGTACCA GAGAATACTG AGGAGCTGGG GCAGACAAAA 
CCAACGTCTA ATCCACAGGT GGTAAATGAG GGAGGAGCCA AACCTGAACT TGCAAGTCAA 
GCCACAGAAG GATCCAAGTC AAATGAAAAT GACTTCTCAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

THUMPD1 ( XM_011545891.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011544193.1 Homo sapiens THUMP domain containing 1 (THUMPD1), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu69542
Clone ID Related Accession (Same CDS sequence)	XM_011545891.1
Accession Version	XM_011545891.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 621bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	THUMP domain-containing protein 1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000016.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTACAAAA CCAAGAAAAA GAAGACTCGA GTTATTTTGC GAATGTTACC CATCTCAGGC 
ACATGCAAGG CTTTTTTAGA AGATATGAAA AAATATGCAG AAACATTTTT GGAACCCTGG 
TTTAAAGCTC CAAACAAAGG GACATTTCAG ATTGTGTACA AATCTCGAAA TAACAGTCAT 
GTGAATAGAG AAGAAGTTAT CAGAGAATTG GCAGGAATAG TGTGCACCCT CAATTCAGAA 
AATAAAGTGG ATCTCACCAA TCCACAGTAC ACAGTGGTAG TAGAAATCAT CAAAGCTGTC 
TGTTGCCTGA GTGTTGTGAA AGATTACATG TTGTTTAGAA AATACAATCT CCAGGAGGTG 
GTGAAGAGCC CTAAGGATCC GTCACAGCTT AACTCAAAGC AGGGAAATGG GAAAGAAGCT 
AAACTGGAAT CTGCGGACAA ATCAGACCAA AACAACACAG CAGAAGGAAA AAATAACCAG 
CAGGTACCAG AGAATACTGA GGAGCTGGGG CAGACAAAAC CAACGTCTAA TCCACAGGTG 
GTAAATGAGG GAGGAGCCAA ACCTGAACTT GCAAGTCAAG CCACAGAAGG ATCCAAGTCA 
AATGAAAATG ACTTCTCATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011544193.1
CDS	451..1071
Translation	MYKTKKKKTRVILRMLPISGTCKAFLEDMKKYAETFLEPWFKAPNKGTFQIVYKSRNNSHVNREEVIRELAGIVCTLNSENKVDLTNPQYTVVVEIIKAVCCLSVVKDYMLFRKYNLQEVVKSPKDPSQLNSKQGNGKEAKLESADKSDQNNTAEGKNNQQVPENTEELGQTKPTSNPQVVNEGGAKPELASQATEGSKSNENDFS

Target ORF information:

RefSeq Version	XM_011545891.1
Organism	Homo sapiens(human)
Definition	Homo sapiens THUMP domain containing 1 (THUMPD1), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011545891.1

ORF Insert Sequence:

ATGTACAAAA CCAAGAAAAA GAAGACTCGA GTTATTTTGC GAATGTTACC CATCTCAGGC 
ACATGCAAGG CTTTTTTAGA AGATATGAAA AAATATGCAG AAACATTTTT GGAACCCTGG 
TTTAAAGCTC CAAACAAAGG GACATTTCAG ATTGTGTACA AATCTCGAAA TAACAGTCAT 
GTGAATAGAG AAGAAGTTAT CAGAGAATTG GCAGGAATAG TGTGCACCCT CAATTCAGAA 
AATAAAGTGG ATCTCACCAA TCCACAGTAC ACAGTGGTAG TAGAAATCAT CAAAGCTGTC 
TGTTGCCTGA GTGTTGTGAA AGATTACATG TTGTTTAGAA AATACAATCT CCAGGAGGTG 
GTGAAGAGCC CTAAGGATCC GTCACAGCTT AACTCAAAGC AGGGAAATGG GAAAGAAGCT 
AAACTGGAAT CTGCGGACAA ATCAGACCAA AACAACACAG CAGAAGGAAA AAATAACCAG 
CAGGTACCAG AGAATACTGA GGAGCTGGGG CAGACAAAAC CAACGTCTAA TCCACAGGTG 
GTAAATGAGG GAGGAGCCAA ACCTGAACTT GCAAGTCAAG CCACAGAAGG ATCCAAGTCA 
AATGAAAATG ACTTCTCATA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

Cytosolic THUMPD1 promotes breast cancer cells invasion and metastasis via the AKT-GSK3-Snail pathway.
Oncotarget8(8)13357-13366(2017 Feb)
Zhang X,Jiang G,Sun M,Zhou H,Miao Y,Liang M,Wang E,Zhang Y

Yeast Kre33 and human NAT10 are conserved 18S rRNA cytosine acetyltransferases that modify tRNAs assisted by the adaptor Tan1/THUMPD1.
Nucleic acids research43(4)2242-58(2015 Feb)
Sharma S,Langhendries JL,Watzinger P,K?tter P,Entian KD,Lafontaine DL

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
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Castello A,Fischer B,Eichelbaum K,Horos R,Beckmann BM,Strein C,Davey NE,Humphreys DT,Preiss T,Steinmetz LM,Krijgsveld J,Hentze MW

Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q.
Genomics60(3)295-308(1999 Sep)
Loftus BJ,Kim UJ,Sneddon VP,Kalush F,Brandon R,Fuhrmann J,Mason T,Crosby ML,Barnstead M,Cronin L,Deslattes Mays A,Cao Y,Xu RX,Kang HL,Mitchell S,Eichler EE,Harris PC,Venter JC,Adams MD

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THUMPD1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

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ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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