FERMT1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	FERMT1
Entrez Gene ID	55612
Full Name	fermitin family member 1
Synonyms	C20orf42,DTGCU2,KIND1,UNC112A,URP1
General protein information	Preferred Names fermitin family member 1 Names fermitin family homolog 1 UNC112 related protein 1 kindlerin kindlin 1 kindlin syndrome protein unc-112-related protein 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 20 Map Location: 20p12.3
Summary	This gene encodes a member of the fermitin family, and contains a FERM domain and a pleckstrin homology domain. The encoded protein is involved in integrin signaling and linkage of the actin cytoskeleton to the extracellular matrix. Mutations in this gene have been linked to Kindler syndrome. [provided by RefSeq, Dec 2009].
Disorder MIM:	607900
Disorder Html:	Kindler syndrome, 173650 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_017671.4	NP_060141.3	fermitin family homolog 1
XM_024451935.1	XP_024307703.1	fermitin family homolog 1 isoform X1
NM_017671.5	NP_060141.3	fermitin family homolog 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	FERMT1	NP_060141.3
Canis lupus familiaris (dog)	FERMT1	XP_542898.2
Pan troglodytes (chimpanzee)	FERMT1	XP_514506.3
	FERMT1	XP_001115968.1
Rattus norvegicus (Norway rat)	Fermt1	NP_001099985.1
Bos taurus (cattle)	FERMT1	NP_001193108.1
Mus musculus (house mouse)	Fermt1	NP_932146.2
Gallus gallus (chicken)	FERMT1	XP_004935303.1
Danio rerio (zebrafish)	fermt1	XP_002665831.3
Xenopus tropicalis (tropical clawed frog)	fermt1	XP_002939191.1

Gene Ontology
Bibliography

Related articles in PubMed

Kindlin supports platelet integrin ?IIb?3 activation by interacting with paxillin.
Gao J, Huang M, Lai J, Mao K, Sun P, Cao Z, Hu Y, Zhang Y, Schulte ML, Jin C, Wang J, White GC, Xu Z, Ma YQ
Journal of cell science130(21)3764-3775(2017 Nov)

Differential expression of Kindlin-1 and Kindlin-2 correlates with esophageal cancer progression and epidemiology.
Wang P, Zhan J, Song J, Wang Y, Fang W, Liu Z, Zhang H
Science China. Life sciences60(11)1214-1222(2017 Nov)

Aggressive periodontitis associated with Kindler syndrome in a large Kindler syndrome pedigree.
Y?ld?r?m TT, Kaya FA, Ta?kesen M, D?ndar S, Bozo?lan A, Tekin GG, Akdeniz S
The Turkish journal of pediatrics59(1)56-61(2017)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These results indicate that Kindlin-1 is essential in EGF-induced re-epithelialization in skin wound healing and provide additional rationale for the clinical application of EGF in the treatment of acute wounds.
Title: Kindlin-1 contributes to EGF-induced re-epithelialization in skin wound healing.

FERMT1 activates the beta-catenin transcriptional activity to promote EMT in CC metastasis.
Title: FERMT1 mediates epithelial-mesenchymal transition to promote colon cancer metastasis via modulation of ?-catenin transcriptional activity.

KIND1 is important not only for keratinocyte proliferation but also for the suppression of UV-induced inflammation and DNA damage.
Title: KIND1 Loss Sensitizes Keratinocytes to UV-Induced Inflammatory Response and DNA Damage.

KS patients' periodontal disease activity could be taken under control with regular follow-up.
Title: Aggressive periodontitis associated with Kindler syndrome in a large Kindler syndrome pedigree.

We show a direct relationship between kindlin-1 abundance and UV-B induced apoptosis in keratinocytes, whereas kindlin-2 overexpression has no compensatory effect.
Title: UV-B-induced cutaneous inflammation and prospects for antioxidant treatment in Kindler syndrome.

The following FERMT1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FERMT1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu18843	NM_017671.5 Latest version!	Homo sapiens fermitin family member 1 (FERMT1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
OHu18843	XM_024451935.1 Latest version!	Homo sapiens fermitin family member 1 (FERMT1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
View Old Accession Versions >>
OHu18843	NM_017671.4	Homo sapiens fermitin family member 1 (FERMT1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

FERMT1 ( NM_017671.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_060141.3 Homo sapiens fermitin family member 1 (FERMT1), mRNA.

Price & Availability↑

CloneID	OHu18843
Clone ID Related Accession (Same CDS sequence)	NM_017671.4 , XM_024451935.1 , NM_017671.5
Accession Version	NM_017671.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2034bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-17
Organism	Homo sapiens(human)
Product	fermitin family homolog 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AB105105.1, AL118505.17, BC040545.1 and AK000123.1. This sequence is a reference standard in the RefSeqGene project. On Oct 26, 2006 this sequence version replaced NM_017671.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB105105.1, AF443278.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCTGTCAT CCACTGACTT TACATTTGCT TCCTGGGAGC TTGTGGTCCG CGTTGACCAT 
CCCAATGAAG AGCAGCAGAA AGACGTCACA CTGAGAGTAT CTGGAGACCT TCATGTTGGA 
GGAGTGATGC TCAAGTTAGT AGAACAGATC AATATATCCC AAGACTGGTC AGACTTTGCT 
CTTTGGTGGG AACAGAAGCA TTGCTGGCTT CTGAAAACCC ACTGGACCCT GGACAAATAT 
GGGGTCCAGG CAGATGCAAA GCTTCTCTTC ACCCCTCAGC ATAAAATGCT GCGCCTTCGT 
CTGCCGAATT TGAAGATGGT GAGGTTGCGA GTCAGCTTCT CAGCTGTGGT TTTTAAAGCT 
GTCAGTGATA TCTGCAAAAT CCTGAATATT AGAAGATCAG AAGAGCTTTC CTTGTTAAAG 
CCGTCTGGTG ACTATTTTAA GAAGAAGAAG AAAAAAGACA AAAATAATAA GGAACCCATA 
ATTGAAGATA TTCTAAACCT GGAGAGTTCT CCAACAGCTT CAGGTTCATC AGTAAGTCCT 
GGTTTATACA GTAAAACCAT GACCCCTATA TATGACCCCA TCAATGGAAC ACCAGCATCA 
TCCACCATGA CTTGGTTCAG TGACAGCCCT TTGACGGAAC AAAACTGCAG CATCCTCGCA 
TTCAGCCAAC CCCCCCAGTC CCCAGAAGCA CTTGCGGATA TGTACCAGCC TCGGTCTCTG 
GTTGATAAAG CCAAGCTCAA TGCAGGTTGG CTAGACTCCT CACGCTCCCT TATGGAACAA 
GGCATCCAAG AGGATGAGCA GCTGCTCTTA CGATTTAAAT ATTATTCTTT CTTCGACTTG 
AATCCTAAAT ATGATGCTGT CCGAATAAAC CAACTCTATG AGCAAGCCAG GTGGGCCATT 
CTCTTAGAAG AAATTGATTG CACAGAGGAA GAAATGTTGA TCTTTGCAGC TCTACAGTAC 
CACATTAGCA AACTGTCGTT GTCTGCTGAA ACACAGGATT TTGCAGGCGA GTCCGAGGTT 
GATGAAATAG AAGCGGCGCT TTCTAATTTG GAAGTAACCC TAGAAGGTGG AAAAGCGGAC 
AGCCTTTTGG AGGACATTAC TGATATCCCT AAACTTGCAG ATAATCTCAA ATTATTTAGG 
CCCAAGAAGT TACTACCAAA AGCTTTCAAA CAATATTGGT TTATCTTTAA AGACACATCC 
ATAGCATACT TTAAAAATAA GGAACTTGAA CAAGGAGAAC CACTAGAAAA ACTAAATCTT 
AGAGGCTGCG AAGTTGTGCC CGATGTAAAT GTAGCAGGAA GAAAATTTGG AATCAAGTTA 
CTAATCCCTG TTGCCGATGG TATGAATGAA ATGTATTTGA GATGTGACCA TGAGAATCAA 
TACGCCCAAT GGATGGCTGC CTGCATGTTG GCATCGAAGG GCAAAACCAT GGCAGACAGC 
TCCTACCAGC CAGAGGTCCT CAACATCCTT TCATTTCTGA GGATGAAAAA CAGGAACTCT 
GCATCTCAGG TGGCTTCCAG TCTCGAAAAC ATGGATATGA ACCCAGAATG TTTTGTGTCA 
CCACGGTGTG CAAAAAGACA CAAATCCAAA CAGCTGGCCG CCCGGATCCT GGAGGCGCAC 
CAGAACGTGG CCCAGATGCC CCTGGTCGAA GCCAAGCTGC GGTTCATCCA GGCGTGGCAG 
TCACTGCCTG AGTTTGGCCT CACCTACTAC CTTGTCAGAT TTAAAGGAAG CAAAAAAGAT 
GACATTCTGG GAGTTTCATA TAACAGGTTG ATTAAAATTG ATGCAGCCAC CGGGATTCCA 
GTGACAACAT GGAGATTCAC AAATATCAAA CAGTGGAATG TAAACTGGGA AACCCGGCAG 
GTGGTCATCG AGTTTGACCA AAACGTCTTT ACTGCTTTCA CCTGCCTGAG TGCAGATTGC 
AAGATTGTGC ACGAGTACAT TGGCGGCTAC ATTTTCTTGT CCACCCGCTC CAAGGACCAG 
AATGAAACAC TCGATGAGGA CTTGTTCCAC AAATTGACCG GCGGTCAGGA TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060141.3
CDS	790..2823
Translation	MLSSTDFTFASWELVVRVDHPNEEQQKDVTLRVSGDLHVGGVMLKLVEQINISQDWSDFALWWEQKHCWLLKTHWTLDKYGVQADAKLLFTPQHKMLRLRLPNLKMVRLRVSFSAVVFKAVSDICKILNIRRSEELSLLKPSGDYFKKKKKKDKNNKEPIIEDILNLESSPTASGSSVSPGLYSKTMTPIYDPINGTPASSTMTWFSDSPLTEQNCSILAFSQPPQSPEALADMYQPRSLVDKAKLNAGWLDSSRSLMEQGIQEDEQLLLRFKYYSFFDLNPKYDAVRINQLYEQARWAILLEEIDCTEEEMLIFAALQYHISKLSLSAETQDFAGESEVDEIEAALSNLEVTLEGGKADSLLEDITDIPKLADNLKLFRPKKLLPKAFKQYWFIFKDTSIAYFKNKELEQGEPLEKLNLRGCEVVPDVNVAGRKFGIKLLIPVADGMNEMYLRCDHENQYAQWMAACMLASKGKTMADSSYQPEVLNILSFLRMKNRNSASQVASSLENMDMNPECFVSPRCAKRHKSKQLAARILEAHQNVAQMPLVEAKLRFIQAWQSLPEFGLTYYLVRFKGSKKDDILGVSYNRLIKIDAATGIPVTTWRFTNIKQWNVNWETRQVVIEFDQNVFTAFTCLSADCKIVHEYIGGYIFLSTRSKDQNETLDEDLFHKLTGGQD

Target ORF information:

RefSeq Version	NM_017671.4
Organism	Homo sapiens(human)
Definition	Homo sapiens fermitin family member 1 (FERMT1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_017671.4

ORF Insert Sequence:

ATGCTGTCAT CCACTGACTT TACATTTGCT TCCTGGGAGC TTGTGGTCCG CGTTGACCAT 
CCCAATGAAG AGCAGCAGAA AGACGTCACA CTGAGAGTAT CTGGAGACCT TCATGTTGGA 
GGAGTGATGC TCAAGTTAGT AGAACAGATC AATATATCCC AAGACTGGTC AGACTTTGCT 
CTTTGGTGGG AACAGAAGCA TTGCTGGCTT CTGAAAACCC ACTGGACCCT GGACAAATAT 
GGGGTCCAGG CAGATGCAAA GCTTCTCTTC ACCCCTCAGC ATAAAATGCT GCGCCTTCGT 
CTGCCGAATT TGAAGATGGT GAGGTTGCGA GTCAGCTTCT CAGCTGTGGT TTTTAAAGCT 
GTCAGTGATA TCTGCAAAAT CCTGAATATT AGAAGATCAG AAGAGCTTTC CTTGTTAAAG 
CCGTCTGGTG ACTATTTTAA GAAGAAGAAG AAAAAAGACA AAAATAATAA GGAACCCATA 
ATTGAAGATA TTCTAAACCT GGAGAGTTCT CCAACAGCTT CAGGTTCATC AGTAAGTCCT 
GGTTTATACA GTAAAACCAT GACCCCTATA TATGACCCCA TCAATGGAAC ACCAGCATCA 
TCCACCATGA CTTGGTTCAG TGACAGCCCT TTGACGGAAC AAAACTGCAG CATCCTCGCA 
TTCAGCCAAC CCCCCCAGTC CCCAGAAGCA CTTGCGGATA TGTACCAGCC TCGGTCTCTG 
GTTGATAAAG CCAAGCTCAA TGCAGGTTGG CTAGACTCCT CACGCTCCCT TATGGAACAA 
GGCATCCAAG AGGATGAGCA GCTGCTCTTA CGATTTAAAT ATTATTCTTT CTTCGACTTG 
AATCCTAAAT ATGATGCTGT CCGAATAAAC CAACTCTATG AGCAAGCCAG GTGGGCCATT 
CTCTTAGAAG AAATTGATTG CACAGAGGAA GAAATGTTGA TCTTTGCAGC TCTACAGTAC 
CACATTAGCA AACTGTCGTT GTCTGCTGAA ACACAGGATT TTGCAGGCGA GTCCGAGGTT 
GATGAAATAG AAGCGGCGCT TTCTAATTTG GAAGTAACCC TAGAAGGTGG AAAAGCGGAC 
AGCCTTTTGG AGGACATTAC TGATATCCCT AAACTTGCAG ATAATCTCAA ATTATTTAGG 
CCCAAGAAGT TACTACCAAA AGCTTTCAAA CAATATTGGT TTATCTTTAA AGACACATCC 
ATAGCATACT TTAAAAATAA GGAACTTGAA CAAGGAGAAC CACTAGAAAA ACTAAATCTT 
AGAGGCTGCG AAGTTGTGCC CGATGTAAAT GTAGCAGGAA GAAAATTTGG AATCAAGTTA 
CTAATCCCTG TTGCCGATGG TATGAATGAA ATGTATTTGA GATGTGACCA TGAGAATCAA 
TACGCCCAAT GGATGGCTGC CTGCATGTTG GCATCGAAGG GCAAAACCAT GGCAGACAGC 
TCCTACCAGC CAGAGGTCCT CAACATCCTT TCATTTCTGA GGATGAAAAA CAGGAACTCT 
GCATCTCAGG TGGCTTCCAG TCTCGAAAAC ATGGATATGA ACCCAGAATG TTTTGTGTCA 
CCACGGTGTG CAAAAAGACA CAAATCCAAA CAGCTGGCCG CCCGGATCCT GGAGGCGCAC 
CAGAACGTGG CCCAGATGCC CCTGGTCGAA GCCAAGCTGC GGTTCATCCA GGCGTGGCAG 
TCACTGCCTG AGTTTGGCCT CACCTACTAC CTTGTCAGAT TTAAAGGAAG CAAAAAAGAT 
GACATTCTGG GAGTTTCATA TAACAGGTTG ATTAAAATTG ATGCAGCCAC CGGGATTCCA 
GTGACAACAT GGAGATTCAC AAATATCAAA CAGTGGAATG TAAACTGGGA AACCCGGCAG 
GTGGTCATCG AGTTTGACCA AAACGTCTTT ACTGCTTTCA CCTGCCTGAG TGCAGATTGC 
AAGATTGTGC ACGAGTACAT TGGCGGCTAC ATTTTCTTGT CCACCCGCTC CAAGGACCAG 
AATGAAACAC TCGATGAGGA CTTGTTCCAC AAATTGACCG GCGGTCAGGA TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FERMT1 ( NM_017671.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_060141.3 Homo sapiens fermitin family member 1 (FERMT1), mRNA.

Price & Availability↑

CloneID	OHu18843
Clone ID Related Accession (Same CDS sequence)	NM_017671.4 , XM_024451935.1 , NM_017671.5
Accession Version	NM_017671.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2034bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-17
Organism	Homo sapiens(human)
Product	fermitin family homolog 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AB105105.1, BC040545.1 and AK000123.1. This sequence is a reference standard in the RefSeqGene project. On Dec 18, 2019 this sequence version replaced NM_017671.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB105105.1, AF443278.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on manual assertion, conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGCTGTCAT CCACTGACTT TACATTTGCT TCCTGGGAGC TTGTGGTCCG CGTTGACCAT 
CCCAATGAAG AGCAGCAGAA AGACGTCACA CTGAGAGTAT CTGGAGACCT TCATGTTGGA 
GGAGTGATGC TCAAGTTAGT AGAACAGATC AATATATCCC AAGACTGGTC AGACTTTGCT 
CTTTGGTGGG AACAGAAGCA TTGCTGGCTT CTGAAAACCC ACTGGACCCT GGACAAATAT 
GGGGTCCAGG CAGATGCAAA GCTTCTCTTC ACCCCTCAGC ATAAAATGCT GCGCCTTCGT 
CTGCCGAATT TGAAGATGGT GAGGTTGCGA GTCAGCTTCT CAGCTGTGGT TTTTAAAGCT 
GTCAGTGATA TCTGCAAAAT CCTGAATATT AGAAGATCAG AAGAGCTTTC CTTGTTAAAG 
CCGTCTGGTG ACTATTTTAA GAAGAAGAAG AAAAAAGACA AAAATAATAA GGAACCCATA 
ATTGAAGATA TTCTAAACCT GGAGAGTTCT CCAACAGCTT CAGGTTCATC AGTAAGTCCT 
GGTTTATACA GTAAAACCAT GACCCCTATA TATGACCCCA TCAATGGAAC ACCAGCATCA 
TCCACCATGA CTTGGTTCAG TGACAGCCCT TTGACGGAAC AAAACTGCAG CATCCTCGCA 
TTCAGCCAAC CCCCCCAGTC CCCAGAAGCA CTTGCGGATA TGTACCAGCC TCGGTCTCTG 
GTTGATAAAG CCAAGCTCAA TGCAGGTTGG CTAGACTCCT CACGCTCCCT TATGGAACAA 
GGCATCCAAG AGGATGAGCA GCTGCTCTTA CGATTTAAAT ATTATTCTTT CTTCGACTTG 
AATCCTAAAT ATGATGCTGT CCGAATAAAC CAACTCTATG AGCAAGCCAG GTGGGCCATT 
CTCTTAGAAG AAATTGATTG CACAGAGGAA GAAATGTTGA TCTTTGCAGC TCTACAGTAC 
CACATTAGCA AACTGTCGTT GTCTGCTGAA ACACAGGATT TTGCAGGCGA GTCCGAGGTT 
GATGAAATAG AAGCGGCGCT TTCTAATTTG GAAGTAACCC TAGAAGGTGG AAAAGCGGAC 
AGCCTTTTGG AGGACATTAC TGATATCCCT AAACTTGCAG ATAATCTCAA ATTATTTAGG 
CCCAAGAAGT TACTACCAAA AGCTTTCAAA CAATATTGGT TTATCTTTAA AGACACATCC 
ATAGCATACT TTAAAAATAA GGAACTTGAA CAAGGAGAAC CACTAGAAAA ACTAAATCTT 
AGAGGCTGCG AAGTTGTGCC CGATGTAAAT GTAGCAGGAA GAAAATTTGG AATCAAGTTA 
CTAATCCCTG TTGCCGATGG TATGAATGAA ATGTATTTGA GATGTGACCA TGAGAATCAA 
TACGCCCAAT GGATGGCTGC CTGCATGTTG GCATCGAAGG GCAAAACCAT GGCAGACAGC 
TCCTACCAGC CAGAGGTCCT CAACATCCTT TCATTTCTGA GGATGAAAAA CAGGAACTCT 
GCATCTCAGG TGGCTTCCAG TCTCGAAAAC ATGGATATGA ACCCAGAATG TTTTGTGTCA 
CCACGGTGTG CAAAAAGACA CAAATCCAAA CAGCTGGCCG CCCGGATCCT GGAGGCGCAC 
CAGAACGTGG CCCAGATGCC CCTGGTCGAA GCCAAGCTGC GGTTCATCCA GGCGTGGCAG 
TCACTGCCTG AGTTTGGCCT CACCTACTAC CTTGTCAGAT TTAAAGGAAG CAAAAAAGAT 
GACATTCTGG GAGTTTCATA TAACAGGTTG ATTAAAATTG ATGCAGCCAC CGGGATTCCA 
GTGACAACAT GGAGATTCAC AAATATCAAA CAGTGGAATG TAAACTGGGA AACCCGGCAG 
GTGGTCATCG AGTTTGACCA AAACGTCTTT ACTGCTTTCA CCTGCCTGAG TGCAGATTGC 
AAGATTGTGC ACGAGTACAT TGGCGGCTAC ATTTTCTTGT CCACCCGCTC CAAGGACCAG 
AATGAAACAC TCGATGAGGA CTTGTTCCAC AAATTGACCG GCGGTCAGGA TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060141.3
CDS	276..2309
Translation	MLSSTDFTFASWELVVRVDHPNEEQQKDVTLRVSGDLHVGGVMLKLVEQINISQDWSDFALWWEQKHCWLLKTHWTLDKYGVQADAKLLFTPQHKMLRLRLPNLKMVRLRVSFSAVVFKAVSDICKILNIRRSEELSLLKPSGDYFKKKKKKDKNNKEPIIEDILNLESSPTASGSSVSPGLYSKTMTPIYDPINGTPASSTMTWFSDSPLTEQNCSILAFSQPPQSPEALADMYQPRSLVDKAKLNAGWLDSSRSLMEQGIQEDEQLLLRFKYYSFFDLNPKYDAVRINQLYEQARWAILLEEIDCTEEEMLIFAALQYHISKLSLSAETQDFAGESEVDEIEAALSNLEVTLEGGKADSLLEDITDIPKLADNLKLFRPKKLLPKAFKQYWFIFKDTSIAYFKNKELEQGEPLEKLNLRGCEVVPDVNVAGRKFGIKLLIPVADGMNEMYLRCDHENQYAQWMAACMLASKGKTMADSSYQPEVLNILSFLRMKNRNSASQVASSLENMDMNPECFVSPRCAKRHKSKQLAARILEAHQNVAQMPLVEAKLRFIQAWQSLPEFGLTYYLVRFKGSKKDDILGVSYNRLIKIDAATGIPVTTWRFTNIKQWNVNWETRQVVIEFDQNVFTAFTCLSADCKIVHEYIGGYIFLSTRSKDQNETLDEDLFHKLTGGQD

Target ORF information:

RefSeq Version	NM_017671.5
Organism	Homo sapiens(human)
Definition	Homo sapiens fermitin family member 1 (FERMT1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_017671.5

ORF Insert Sequence:

ATGCTGTCAT CCACTGACTT TACATTTGCT TCCTGGGAGC TTGTGGTCCG CGTTGACCAT 
CCCAATGAAG AGCAGCAGAA AGACGTCACA CTGAGAGTAT CTGGAGACCT TCATGTTGGA 
GGAGTGATGC TCAAGTTAGT AGAACAGATC AATATATCCC AAGACTGGTC AGACTTTGCT 
CTTTGGTGGG AACAGAAGCA TTGCTGGCTT CTGAAAACCC ACTGGACCCT GGACAAATAT 
GGGGTCCAGG CAGATGCAAA GCTTCTCTTC ACCCCTCAGC ATAAAATGCT GCGCCTTCGT 
CTGCCGAATT TGAAGATGGT GAGGTTGCGA GTCAGCTTCT CAGCTGTGGT TTTTAAAGCT 
GTCAGTGATA TCTGCAAAAT CCTGAATATT AGAAGATCAG AAGAGCTTTC CTTGTTAAAG 
CCGTCTGGTG ACTATTTTAA GAAGAAGAAG AAAAAAGACA AAAATAATAA GGAACCCATA 
ATTGAAGATA TTCTAAACCT GGAGAGTTCT CCAACAGCTT CAGGTTCATC AGTAAGTCCT 
GGTTTATACA GTAAAACCAT GACCCCTATA TATGACCCCA TCAATGGAAC ACCAGCATCA 
TCCACCATGA CTTGGTTCAG TGACAGCCCT TTGACGGAAC AAAACTGCAG CATCCTCGCA 
TTCAGCCAAC CCCCCCAGTC CCCAGAAGCA CTTGCGGATA TGTACCAGCC TCGGTCTCTG 
GTTGATAAAG CCAAGCTCAA TGCAGGTTGG CTAGACTCCT CACGCTCCCT TATGGAACAA 
GGCATCCAAG AGGATGAGCA GCTGCTCTTA CGATTTAAAT ATTATTCTTT CTTCGACTTG 
AATCCTAAAT ATGATGCTGT CCGAATAAAC CAACTCTATG AGCAAGCCAG GTGGGCCATT 
CTCTTAGAAG AAATTGATTG CACAGAGGAA GAAATGTTGA TCTTTGCAGC TCTACAGTAC 
CACATTAGCA AACTGTCGTT GTCTGCTGAA ACACAGGATT TTGCAGGCGA GTCCGAGGTT 
GATGAAATAG AAGCGGCGCT TTCTAATTTG GAAGTAACCC TAGAAGGTGG AAAAGCGGAC 
AGCCTTTTGG AGGACATTAC TGATATCCCT AAACTTGCAG ATAATCTCAA ATTATTTAGG 
CCCAAGAAGT TACTACCAAA AGCTTTCAAA CAATATTGGT TTATCTTTAA AGACACATCC 
ATAGCATACT TTAAAAATAA GGAACTTGAA CAAGGAGAAC CACTAGAAAA ACTAAATCTT 
AGAGGCTGCG AAGTTGTGCC CGATGTAAAT GTAGCAGGAA GAAAATTTGG AATCAAGTTA 
CTAATCCCTG TTGCCGATGG TATGAATGAA ATGTATTTGA GATGTGACCA TGAGAATCAA 
TACGCCCAAT GGATGGCTGC CTGCATGTTG GCATCGAAGG GCAAAACCAT GGCAGACAGC 
TCCTACCAGC CAGAGGTCCT CAACATCCTT TCATTTCTGA GGATGAAAAA CAGGAACTCT 
GCATCTCAGG TGGCTTCCAG TCTCGAAAAC ATGGATATGA ACCCAGAATG TTTTGTGTCA 
CCACGGTGTG CAAAAAGACA CAAATCCAAA CAGCTGGCCG CCCGGATCCT GGAGGCGCAC 
CAGAACGTGG CCCAGATGCC CCTGGTCGAA GCCAAGCTGC GGTTCATCCA GGCGTGGCAG 
TCACTGCCTG AGTTTGGCCT CACCTACTAC CTTGTCAGAT TTAAAGGAAG CAAAAAAGAT 
GACATTCTGG GAGTTTCATA TAACAGGTTG ATTAAAATTG ATGCAGCCAC CGGGATTCCA 
GTGACAACAT GGAGATTCAC AAATATCAAA CAGTGGAATG TAAACTGGGA AACCCGGCAG 
GTGGTCATCG AGTTTGACCA AAACGTCTTT ACTGCTTTCA CCTGCCTGAG TGCAGATTGC 
AAGATTGTGC ACGAGTACAT TGGCGGCTAC ATTTTCTTGT CCACCCGCTC CAAGGACCAG 
AATGAAACAC TCGATGAGGA CTTGTTCCAC AAATTGACCG GCGGTCAGGA TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FERMT1 ( XM_024451935.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024307703.1 Homo sapiens fermitin family member 1 (FERMT1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu18843
Clone ID Related Accession (Same CDS sequence)	NM_017671.4 , XM_024451935.1 , NM_017671.5
Accession Version	XM_024451935.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2034bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	fermitin family homolog 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000020.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGTCAT CCACTGACTT TACATTTGCT TCCTGGGAGC TTGTGGTCCG CGTTGACCAT 
CCCAATGAAG AGCAGCAGAA AGACGTCACA CTGAGAGTAT CTGGAGACCT TCATGTTGGA 
GGAGTGATGC TCAAGTTAGT AGAACAGATC AATATATCCC AAGACTGGTC AGACTTTGCT 
CTTTGGTGGG AACAGAAGCA TTGCTGGCTT CTGAAAACCC ACTGGACCCT GGACAAATAT 
GGGGTCCAGG CAGATGCAAA GCTTCTCTTC ACCCCTCAGC ATAAAATGCT GCGCCTTCGT 
CTGCCGAATT TGAAGATGGT GAGGTTGCGA GTCAGCTTCT CAGCTGTGGT TTTTAAAGCT 
GTCAGTGATA TCTGCAAAAT CCTGAATATT AGAAGATCAG AAGAGCTTTC CTTGTTAAAG 
CCGTCTGGTG ACTATTTTAA GAAGAAGAAG AAAAAAGACA AAAATAATAA GGAACCCATA 
ATTGAAGATA TTCTAAACCT GGAGAGTTCT CCAACAGCTT CAGGTTCATC AGTAAGTCCT 
GGTTTATACA GTAAAACCAT GACCCCTATA TATGACCCCA TCAATGGAAC ACCAGCATCA 
TCCACCATGA CTTGGTTCAG TGACAGCCCT TTGACGGAAC AAAACTGCAG CATCCTCGCA 
TTCAGCCAAC CCCCCCAGTC CCCAGAAGCA CTTGCGGATA TGTACCAGCC TCGGTCTCTG 
GTTGATAAAG CCAAGCTCAA TGCAGGTTGG CTAGACTCCT CACGCTCCCT TATGGAACAA 
GGCATCCAAG AGGATGAGCA GCTGCTCTTA CGATTTAAAT ATTATTCTTT CTTCGACTTG 
AATCCTAAAT ATGATGCTGT CCGAATAAAC CAACTCTATG AGCAAGCCAG GTGGGCCATT 
CTCTTAGAAG AAATTGATTG CACAGAGGAA GAAATGTTGA TCTTTGCAGC TCTACAGTAC 
CACATTAGCA AACTGTCGTT GTCTGCTGAA ACACAGGATT TTGCAGGCGA GTCCGAGGTT 
GATGAAATAG AAGCGGCGCT TTCTAATTTG GAAGTAACCC TAGAAGGTGG AAAAGCGGAC 
AGCCTTTTGG AGGACATTAC TGATATCCCT AAACTTGCAG ATAATCTCAA ATTATTTAGG 
CCCAAGAAGT TACTACCAAA AGCTTTCAAA CAATATTGGT TTATCTTTAA AGACACATCC 
ATAGCATACT TTAAAAATAA GGAACTTGAA CAAGGAGAAC CACTAGAAAA ACTAAATCTT 
AGAGGCTGCG AAGTTGTGCC CGATGTAAAT GTAGCAGGAA GAAAATTTGG AATCAAGTTA 
CTAATCCCTG TTGCCGATGG TATGAATGAA ATGTATTTGA GATGTGACCA TGAGAATCAA 
TACGCCCAAT GGATGGCTGC CTGCATGTTG GCATCGAAGG GCAAAACCAT GGCAGACAGC 
TCCTACCAGC CAGAGGTCCT CAACATCCTT TCATTTCTGA GGATGAAAAA CAGGAACTCT 
GCATCTCAGG TGGCTTCCAG TCTCGAAAAC ATGGATATGA ACCCAGAATG TTTTGTGTCA 
CCACGGTGTG CAAAAAGACA CAAATCCAAA CAGCTGGCCG CCCGGATCCT GGAGGCGCAC 
CAGAACGTGG CCCAGATGCC CCTGGTCGAA GCCAAGCTGC GGTTCATCCA GGCGTGGCAG 
TCACTGCCTG AGTTTGGCCT CACCTACTAC CTTGTCAGAT TTAAAGGAAG CAAAAAAGAT 
GACATTCTGG GAGTTTCATA TAACAGGTTG ATTAAAATTG ATGCAGCCAC CGGGATTCCA 
GTGACAACAT GGAGATTCAC AAATATCAAA CAGTGGAATG TAAACTGGGA AACCCGGCAG 
GTGGTCATCG AGTTTGACCA AAACGTCTTT ACTGCTTTCA CCTGCCTGAG TGCAGATTGC 
AAGATTGTGC ACGAGTACAT TGGCGGCTAC ATTTTCTTGT CCACCCGCTC CAAGGACCAG 
AATGAAACAC TCGATGAGGA CTTGTTCCAC AAATTGACCG GCGGTCAGGA TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024307703.1
CDS	858..2891
Translation	MLSSTDFTFASWELVVRVDHPNEEQQKDVTLRVSGDLHVGGVMLKLVEQINISQDWSDFALWWEQKHCWLLKTHWTLDKYGVQADAKLLFTPQHKMLRLRLPNLKMVRLRVSFSAVVFKAVSDICKILNIRRSEELSLLKPSGDYFKKKKKKDKNNKEPIIEDILNLESSPTASGSSVSPGLYSKTMTPIYDPINGTPASSTMTWFSDSPLTEQNCSILAFSQPPQSPEALADMYQPRSLVDKAKLNAGWLDSSRSLMEQGIQEDEQLLLRFKYYSFFDLNPKYDAVRINQLYEQARWAILLEEIDCTEEEMLIFAALQYHISKLSLSAETQDFAGESEVDEIEAALSNLEVTLEGGKADSLLEDITDIPKLADNLKLFRPKKLLPKAFKQYWFIFKDTSIAYFKNKELEQGEPLEKLNLRGCEVVPDVNVAGRKFGIKLLIPVADGMNEMYLRCDHENQYAQWMAACMLASKGKTMADSSYQPEVLNILSFLRMKNRNSASQVASSLENMDMNPECFVSPRCAKRHKSKQLAARILEAHQNVAQMPLVEAKLRFIQAWQSLPEFGLTYYLVRFKGSKKDDILGVSYNRLIKIDAATGIPVTTWRFTNIKQWNVNWETRQVVIEFDQNVFTAFTCLSADCKIVHEYIGGYIFLSTRSKDQNETLDEDLFHKLTGGQD

Target ORF information:

RefSeq Version	XM_024451935.1
Organism	Homo sapiens(human)
Definition	Homo sapiens fermitin family member 1 (FERMT1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024451935.1

ORF Insert Sequence:

ATGCTGTCAT CCACTGACTT TACATTTGCT TCCTGGGAGC TTGTGGTCCG CGTTGACCAT 
CCCAATGAAG AGCAGCAGAA AGACGTCACA CTGAGAGTAT CTGGAGACCT TCATGTTGGA 
GGAGTGATGC TCAAGTTAGT AGAACAGATC AATATATCCC AAGACTGGTC AGACTTTGCT 
CTTTGGTGGG AACAGAAGCA TTGCTGGCTT CTGAAAACCC ACTGGACCCT GGACAAATAT 
GGGGTCCAGG CAGATGCAAA GCTTCTCTTC ACCCCTCAGC ATAAAATGCT GCGCCTTCGT 
CTGCCGAATT TGAAGATGGT GAGGTTGCGA GTCAGCTTCT CAGCTGTGGT TTTTAAAGCT 
GTCAGTGATA TCTGCAAAAT CCTGAATATT AGAAGATCAG AAGAGCTTTC CTTGTTAAAG 
CCGTCTGGTG ACTATTTTAA GAAGAAGAAG AAAAAAGACA AAAATAATAA GGAACCCATA 
ATTGAAGATA TTCTAAACCT GGAGAGTTCT CCAACAGCTT CAGGTTCATC AGTAAGTCCT 
GGTTTATACA GTAAAACCAT GACCCCTATA TATGACCCCA TCAATGGAAC ACCAGCATCA 
TCCACCATGA CTTGGTTCAG TGACAGCCCT TTGACGGAAC AAAACTGCAG CATCCTCGCA 
TTCAGCCAAC CCCCCCAGTC CCCAGAAGCA CTTGCGGATA TGTACCAGCC TCGGTCTCTG 
GTTGATAAAG CCAAGCTCAA TGCAGGTTGG CTAGACTCCT CACGCTCCCT TATGGAACAA 
GGCATCCAAG AGGATGAGCA GCTGCTCTTA CGATTTAAAT ATTATTCTTT CTTCGACTTG 
AATCCTAAAT ATGATGCTGT CCGAATAAAC CAACTCTATG AGCAAGCCAG GTGGGCCATT 
CTCTTAGAAG AAATTGATTG CACAGAGGAA GAAATGTTGA TCTTTGCAGC TCTACAGTAC 
CACATTAGCA AACTGTCGTT GTCTGCTGAA ACACAGGATT TTGCAGGCGA GTCCGAGGTT 
GATGAAATAG AAGCGGCGCT TTCTAATTTG GAAGTAACCC TAGAAGGTGG AAAAGCGGAC 
AGCCTTTTGG AGGACATTAC TGATATCCCT AAACTTGCAG ATAATCTCAA ATTATTTAGG 
CCCAAGAAGT TACTACCAAA AGCTTTCAAA CAATATTGGT TTATCTTTAA AGACACATCC 
ATAGCATACT TTAAAAATAA GGAACTTGAA CAAGGAGAAC CACTAGAAAA ACTAAATCTT 
AGAGGCTGCG AAGTTGTGCC CGATGTAAAT GTAGCAGGAA GAAAATTTGG AATCAAGTTA 
CTAATCCCTG TTGCCGATGG TATGAATGAA ATGTATTTGA GATGTGACCA TGAGAATCAA 
TACGCCCAAT GGATGGCTGC CTGCATGTTG GCATCGAAGG GCAAAACCAT GGCAGACAGC 
TCCTACCAGC CAGAGGTCCT CAACATCCTT TCATTTCTGA GGATGAAAAA CAGGAACTCT 
GCATCTCAGG TGGCTTCCAG TCTCGAAAAC ATGGATATGA ACCCAGAATG TTTTGTGTCA 
CCACGGTGTG CAAAAAGACA CAAATCCAAA CAGCTGGCCG CCCGGATCCT GGAGGCGCAC 
CAGAACGTGG CCCAGATGCC CCTGGTCGAA GCCAAGCTGC GGTTCATCCA GGCGTGGCAG 
TCACTGCCTG AGTTTGGCCT CACCTACTAC CTTGTCAGAT TTAAAGGAAG CAAAAAAGAT 
GACATTCTGG GAGTTTCATA TAACAGGTTG ATTAAAATTG ATGCAGCCAC CGGGATTCCA 
GTGACAACAT GGAGATTCAC AAATATCAAA CAGTGGAATG TAAACTGGGA AACCCGGCAG 
GTGGTCATCG AGTTTGACCA AAACGTCTTT ACTGCTTTCA CCTGCCTGAG TGCAGATTGC 
AAGATTGTGC ACGAGTACAT TGGCGGCTAC ATTTTCTTGT CCACCCGCTC CAAGGACCAG 
AATGAAACAC TCGATGAGGA CTTGTTCCAC AAATTGACCG GCGGTCAGGA TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Kindlin supports platelet integrin ?IIb?3 activation by interacting with paxillin.
Journal of cell science130(21)3764-3775(2017 Nov)
Gao J,Huang M,Lai J,Mao K,Sun P,Cao Z,Hu Y,Zhang Y,Schulte ML,Jin C,Wang J,White GC,Xu Z,Ma YQ

Differential expression of Kindlin-1 and Kindlin-2 correlates with esophageal cancer progression and epidemiology.
Science China. Life sciences60(11)1214-1222(2017 Nov)
Wang P,Zhan J,Song J,Wang Y,Fang W,Liu Z,Zhang H

Aggressive periodontitis associated with Kindler syndrome in a large Kindler syndrome pedigree.
The Turkish journal of pediatrics59(1)56-61(2017)
Y?ld?r?m TT,Kaya FA,Ta?kesen M,D?ndar S,Bozo?lan A,Tekin GG,Akdeniz S

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

FERMT1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報