BATF3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	BATF3
Entrez Gene ID	55509
Full Name	basic leucine zipper ATF-like transcription factor 3
Synonyms	JDP1,JUNDM1,SNFT
General protein information	Preferred Names basic leucine zipper ATF-like transcription factor 3 Names basic leucine zipper transcriptional factor ATF-like 3 21 kDa small nuclear factor isolated from T-cells 21-kD small nuclear factor isolated from T cells B-ATF-3 Jun dimerization protein 1 Jun dimerization protein p21SNFT basic leucine zipper transcription factor, ATF-like 3
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1q32.3
Summary	This gene encodes a member of the basic leucine zipper protein family. The encoded protein functions as a transcriptional repressor when heterodimerizing with JUN. The protein may play a role in repression of interleukin-2 and matrix metalloproteinase-1 transcription.[provided by RefSeq, Feb 2009].
Disorder MIM:	612470

mRNA and Protein(s)

mRNA	Protein	Name
NM_018664.2	NP_061134.1	basic leucine zipper transcriptional factor ATF-like 3
XM_017001683.1	XP_016857172.1	basic leucine zipper transcriptional factor ATF-like 3 isoform X1
NM_018664.3	NP_061134.1	basic leucine zipper transcriptional factor ATF-like 3

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Batf3	NP_068637.1
Gallus gallus (chicken)	BATF3	XP_004935392.1
Xenopus tropicalis (tropical clawed frog)	batf3	XP_004914833.1
Pan troglodytes (chimpanzee)	BATF3	XP_530226.4
Mus musculus (house mouse)	Batf3	NP_084336.1
Danio rerio (zebrafish)	batf3	NP_001038857.1
Homo sapiens (human)	BATF3	NP_061134.1
	LOC710551	XP_001107737.1
Canis lupus familiaris (dog)	BATF3	XP_547403.2
Bos taurus (cattle)	BATF3	NP_001180164.1

Gene Ontology
Bibliography

Related articles in PubMed

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

Identification and characterization of BATF3 as a context-specific coactivator of the glucocorticoid receptor.
Birth P, Sch?ne S, Stelzl U, Meijsing SH
PloS one12(7)e0181219(2017)

The Expression Quantitative Trait Loci in Immune Pathways and their Effect on Cutaneous Melanoma Prognosis.
Vogelsang M, Martinez CN, Rendleman J, Bapodra A, Malecek K, Romanchuk A, Kazlow E, Shapiro RL, Berman RS, Krogsgaard M, Osman I, Kirchhoff T
Clinical cancer research : an official journal of the American Association for Cancer Research22(13)3268-80(2016 Jul)

Cutting Edge: Roles for Batf3-Dependent APCs in the Rejection of Minor Histocompatibility Antigen-Mismatched Grafts.
Atif SM, Nelsen MK, Gibbings SL, Desch AN, Kedl RM, Gill RG, Marrack P, Murphy KM, Grazia TJ, Henson PM, Jakubzick CV
Journal of immunology (Baltimore, Md. : 1950)195(1)46-50(2015 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Basic Leucine Zipper ATF-Like Transcription Factor 3 (BATF3), an AP-1 family transcription factor, is a glucocorticoid receptor coregulator whose interaction with glucocorticoid receptor is modulated by the lever arm.
Title: Identification and characterization of BATF3 as a context-specific coactivator of the glucocorticoid receptor.

Batf3-dependent dendritic cells elicit the rejection of cells and grafts expressing mismatched minor histocompatibility antigens.
Title: Cutting Edge: Roles for Batf3-Dependent APCs in the Rejection of Minor Histocompatibility Antigen-Mismatched Grafts.

overexpression of p21SNFT in HepG2 cells leads to repression of matrix metalloproteinase-1 by 70-80%
Title: Transcriptional repression of MMP-1 by p21SNFT and reduced in vitro invasiveness of hepatocarcinoma cells.

correlation of transcriptional repression by p21(SNFT) with changes in DNA.NF-AT complex interactions
Title: Correlation of transcriptional repression by p21(SNFT) with changes in DNA.NF-AT complex interactions.

The following BATF3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the BATF3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu02832	NM_018664.3 Latest version!	Homo sapiens basic leucine zipper ATF-like transcription factor 3 (BATF3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu90191	XM_017001683.1 Latest version!	Homo sapiens basic leucine zipper ATF-like transcription factor 3 (BATF3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OHu02832	NM_018664.2	Homo sapiens basic leucine zipper ATF-like transcription factor 3 (BATF3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

BATF3 ( NM_018664.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_061134.1 Homo sapiens basic leucine zipper ATF-like transcription factor 3 (BATF3), mRNA.

Price & Availability↑

CloneID	OHu02832
Clone ID Related Accession (Same CDS sequence)	NM_018664.2 , NM_018664.3
Accession Version	NM_018664.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 384bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	basic leucine zipper transcriptional factor ATF-like 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF255346.1, BC117491.1 and BG184570.1. On Feb 20, 2009 this sequence version replaced NM_018664.1. ##Evidence-Data-START## Transcript exon combination :: AF255346.1, SRR1163655.220166.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2149004, SAMN03465406 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCGCAAG GGCTCCCGGC CGCCGGCAGC GTCCTGCAGA GGAGCGTCGC GGCGCCCGGG 
AACCAGCCGC AGCCGCAGCC GCAGCAGCAG AGCCCTGAGG ATGATGACAG GAAGGTCCGA 
AGGAGAGAAA AAAACCGAGT TGCTGCTCAG AGAAGTCGGA AGAAGCAGAC CCAGAAGGCT 
GACAAGCTCC ATGAGGAATA TGAGAGCCTG GAGCAAGAAA ACACCATGCT GCGGAGAGAG 
ATCGGGAAGC TGACAGAGGA GCTGAAGCAC CTGACAGAGG CACTGAAGGA GCACGAGAAG 
ATGTGCCCGC TGCTGCTCTG CCCTATGAAC TTTGTGCCAG TGCCTCCCCG GCCGGACCCT 
GTGGCCGGCT GCTTGCCCCG ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_061134.1
CDS	224..607
Translation	MSQGLPAAGSVLQRSVAAPGNQPQPQPQQQSPEDDDRKVRRREKNRVAAQRSRKKQTQKADKLHEEYESLEQENTMLRREIGKLTEELKHLTEALKEHEKMCPLLLCPMNFVPVPPRPDPVAGCLPR

Target ORF information:

RefSeq Version	NM_018664.2
Organism	Homo sapiens(human)
Definition	Homo sapiens basic leucine zipper ATF-like transcription factor 3 (BATF3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018664.2

ORF Insert Sequence:

ATGTCGCAAG GGCTCCCGGC CGCCGGCAGC GTCCTGCAGA GGAGCGTCGC GGCGCCCGGG 
AACCAGCCGC AGCCGCAGCC GCAGCAGCAG AGCCCTGAGG ATGATGACAG GAAGGTCCGA 
AGGAGAGAAA AAAACCGAGT TGCTGCTCAG AGAAGTCGGA AGAAGCAGAC CCAGAAGGCT 
GACAAGCTCC ATGAGGAATA TGAGAGCCTG GAGCAAGAAA ACACCATGCT GCGGAGAGAG 
ATCGGGAAGC TGACAGAGGA GCTGAAGCAC CTGACAGAGG CACTGAAGGA GCACGAGAAG 
ATGTGCCCGC TGCTGCTCTG CCCTATGAAC TTTGTGCCAG TGCCTCCCCG GCCGGACCCT 
GTGGCCGGCT GCTTGCCCCG ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BATF3 ( NM_018664.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_061134.1 Homo sapiens basic leucine zipper ATF-like transcription factor 3 (BATF3), mRNA.

Price & Availability↑

CloneID	OHu02832
Clone ID Related Accession (Same CDS sequence)	NM_018664.2 , NM_018664.3
Accession Version	NM_018664.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 384bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	basic leucine zipper transcriptional factor ATF-like 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF255346.1, BC117491.1 and BG184570.1. On Nov 23, 2018 this sequence version replaced NM_018664.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.579318.1, AF255346.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2149004, SAMN03465406 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000243440.2/ ENSP00000243440.1 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTCGCAAG GGCTCCCGGC CGCCGGCAGC GTCCTGCAGA GGAGCGTCGC GGCGCCCGGG 
AACCAGCCGC AGCCGCAGCC GCAGCAGCAG AGCCCTGAGG ATGATGACAG GAAGGTCCGA 
AGGAGAGAAA AAAACCGAGT TGCTGCTCAG AGAAGTCGGA AGAAGCAGAC CCAGAAGGCT 
GACAAGCTCC ATGAGGAATA TGAGAGCCTG GAGCAAGAAA ACACCATGCT GCGGAGAGAG 
ATCGGGAAGC TGACAGAGGA GCTGAAGCAC CTGACAGAGG CACTGAAGGA GCACGAGAAG 
ATGTGCCCGC TGCTGCTCTG CCCTATGAAC TTTGTGCCAG TGCCTCCCCG GCCGGACCCT 
GTGGCCGGCT GCTTGCCCCG ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_061134.1
CDS	79..462
Translation	MSQGLPAAGSVLQRSVAAPGNQPQPQPQQQSPEDDDRKVRRREKNRVAAQRSRKKQTQKADKLHEEYESLEQENTMLRREIGKLTEELKHLTEALKEHEKMCPLLLCPMNFVPVPPRPDPVAGCLPR

Target ORF information:

RefSeq Version	NM_018664.3
Organism	Homo sapiens(human)
Definition	Homo sapiens basic leucine zipper ATF-like transcription factor 3 (BATF3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018664.3

ORF Insert Sequence:

ATGTCGCAAG GGCTCCCGGC CGCCGGCAGC GTCCTGCAGA GGAGCGTCGC GGCGCCCGGG 
AACCAGCCGC AGCCGCAGCC GCAGCAGCAG AGCCCTGAGG ATGATGACAG GAAGGTCCGA 
AGGAGAGAAA AAAACCGAGT TGCTGCTCAG AGAAGTCGGA AGAAGCAGAC CCAGAAGGCT 
GACAAGCTCC ATGAGGAATA TGAGAGCCTG GAGCAAGAAA ACACCATGCT GCGGAGAGAG 
ATCGGGAAGC TGACAGAGGA GCTGAAGCAC CTGACAGAGG CACTGAAGGA GCACGAGAAG 
ATGTGCCCGC TGCTGCTCTG CCCTATGAAC TTTGTGCCAG TGCCTCCCCG GCCGGACCCT 
GTGGCCGGCT GCTTGCCCCG ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

BATF3 ( XM_017001683.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016857172.1 Homo sapiens basic leucine zipper ATF-like transcription factor 3 (BATF3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu90191
Clone ID Related Accession (Same CDS sequence)	XM_017001683.1
Accession Version	XM_017001683.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 417bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	basic leucine zipper transcriptional factor ATF-like 3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCGCAAG GGCTCCCGGC CGCCGGCAGC GTCCTGCAGA GGAGCGTCGC GGCGCCCGGG 
AACCAGCCGC AGCCGCAGCC GCAGCAGCAG AGCCCTGAGG ATGATGACAG GAAGGTCCGA 
AGGAGAGAAA AAAACCGAGT TGCTGCTCAG AGAAGTCGGA AGAAGCAGAC CCAGAAGGCT 
GACAAGCTCC ATGAGTTAAT GGAGCGAACC ATCTTTCTCA TCACTCAAAT CAGAAGCCTA 
GGATTTATCC TAAGCCATTC CTTTTCCCTC CGCCCTCATG CATACACCTG CATAATCCTG 
CAGTTGGGAC GTGGAGCTGC TCCATACCAG GAACTGGCCT TGAAAGCATC CAAGGATCTA 
TCTGAGGAAT GGGCCACCAT TCCATGTTCT TGTCTTTGTC GGGGTTGGTG TGTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016857172.1
CDS	182..598
Translation	MSQGLPAAGSVLQRSVAAPGNQPQPQPQQQSPEDDDRKVRRREKNRVAAQRSRKKQTQKADKLHELMERTIFLITQIRSLGFILSHSFSLRPHAYTCIILQLGRGAAPYQELALKASKDLSEEWATIPCSCLCRGWCV

Target ORF information:

RefSeq Version	XM_017001683.1
Organism	Homo sapiens(human)
Definition	Homo sapiens basic leucine zipper ATF-like transcription factor 3 (BATF3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017001683.1

ORF Insert Sequence:

ATGTCGCAAG GGCTCCCGGC CGCCGGCAGC GTCCTGCAGA GGAGCGTCGC GGCGCCCGGG 
AACCAGCCGC AGCCGCAGCC GCAGCAGCAG AGCCCTGAGG ATGATGACAG GAAGGTCCGA 
AGGAGAGAAA AAAACCGAGT TGCTGCTCAG AGAAGTCGGA AGAAGCAGAC CCAGAAGGCT 
GACAAGCTCC ATGAGTTAAT GGAGCGAACC ATCTTTCTCA TCACTCAAAT CAGAAGCCTA 
GGATTTATCC TAAGCCATTC CTTTTCCCTC CGCCCTCATG CATACACCTG CATAATCCTG 
CAGTTGGGAC GTGGAGCTGC TCCATACCAG GAACTGGCCT TGAAAGCATC CAAGGATCTA 
TCTGAGGAAT GGGCCACCAT TCCATGTTCT TGTCTTTGTC GGGGTTGGTG TGTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

Identification and characterization of BATF3 as a context-specific coactivator of the glucocorticoid receptor.
PloS one12(7)e0181219(2017)
Birth P,Sch?ne S,Stelzl U,Meijsing SH

The Expression Quantitative Trait Loci in Immune Pathways and their Effect on Cutaneous Melanoma Prognosis.
Clinical cancer research : an official journal of the American Association for Cancer Research22(13)3268-80(2016 Jul)
Vogelsang M,Martinez CN,Rendleman J,Bapodra A,Malecek K,Romanchuk A,Kazlow E,Shapiro RL,Berman RS,Krogsgaard M,Osman I,Kirchhoff T

Cutting Edge: Roles for Batf3-Dependent APCs in the Rejection of Minor Histocompatibility Antigen-Mismatched Grafts.
Journal of immunology (Baltimore, Md. : 1950)195(1)46-50(2015 Jul)
Atif SM,Nelsen MK,Gibbings SL,Desch AN,Kedl RM,Gill RG,Marrack P,Murphy KM,Grazia TJ,Henson PM,Jakubzick CV

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BATF3 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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