Gene Symbol | PRCC |
Entrez Gene ID | 5546 |
Full Name | papillary renal cell carcinoma (translocation-associated) |
Synonyms | RCCP1,TPRC |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a protein that may play a role in pre-mRNA splicing. Chromosomal translocations (X;1)(p11;q21) that result in fusion of this gene to TFE3 (GeneID 7030) have been associated with papillary renal cell carcinoma. A PRCC-TFE3 fusion protein is expressed in affected carcinomas and is likely associated with altered gene transactivation. This fusion protein has also been associated with disruption of the cell cycle.[provided by RefSeq, Aug 2010]. |
Disorder MIM: | |
Disorder Html: | Renal cell carcinoma, papillary, 605074 (3) |