TMEM176A cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TMEM176A
Entrez Gene ID	55365
Full Name	transmembrane protein 176A
Synonyms	GS188,HCA112,MS4B1
General protein information	Preferred Names transmembrane protein 176A Names transmembrane protein 176A hepatocellular carcinoma-associated antigen 112 likley ortholog of mouse GS188
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 7 Map Location: 7q36.1
Disorder MIM:	610334

mRNA and Protein(s)

mRNA	Protein	Name
XM_011516376.2	XP_011514678.1	transmembrane protein 176A isoform X1
XM_024446824.1	XP_024302592.1	transmembrane protein 176A isoform X5
NM_018487.2	NP_060957.2	transmembrane protein 176A
XM_011516378.2	XP_011514680.1	transmembrane protein 176A isoform X4
NM_018487.3	NP_060957.2	transmembrane protein 176A
XM_011516376.3	XP_011514678.1	transmembrane protein 176A isoform X1
XM_011516377.2	XP_011514679.1	transmembrane protein 176A isoform X2
XM_017012393.1	XP_016867882.1	transmembrane protein 176A isoform X3

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	TMEM176A	XP_003318949.1
	TMEM176A	XP_002803568.1
Rattus norvegicus (Norway rat)	Tmem176a	NP_001034097.1
Canis lupus familiaris (dog)	TMEM176A	XP_532758.1
Mus musculus (house mouse)	Tmem176a	NP_001091741.1
Homo sapiens (human)	TMEM176A	NP_060957.2

Gene Ontology
Bibliography

Related articles in PubMed

Exome sequences of multiplex, multigenerational families reveal schizophrenia risk loci with potential implications for neurocognitive performance.
Kos MZ, Carless MA, Peralta J, Curran JE, Quillen EE, Almeida M, Blackburn A, Blondell L, Roalf DR, Pogue-Geile MF, Gur RC, G?ring HHH, Nimgaonkar VL, Gur RE, Almasy L
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics174(8)817-827(2017 Dec)

Methylation of TMEM176A is an independent prognostic marker and is involved in human colorectal cancer development.
Gao D, Han Y, Yang Y, Herman JG, Linghu E, Zhan Q, Fuks F, Lu ZJ, Guo M
Epigenetics12(7)575-583(2017 07)

ROR?t+ cells selectively express redundant cation channels linked to the Golgi apparatus.
Drujont L, Lemoine A, Moreau A, Bienvenu G, Lancien M, Cens T, Guillot F, B?riou G, Bouchet-Delbos L, Fehling HJ, Chiffoleau E, Nicot AB, Charnet P, Martin JC, Josien R, Cuturi MC, Louvet C
Scientific reports623682(2016 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Expression of TMEM176A in colorectal cancer cells is regulated by promoter region methylation. Methylation of TMEM176A was associated with tumor metastasis and was an independent prognostic factor for 5-year overall survival.
Title: Methylation of TMEM176A is an independent prognostic marker and is involved in human colorectal cancer development.

Study characterized Tmem176a and b expression in RORgamma t+ lymphocytes at transcriptional and protein levels and present evidence that both genes exert a redundant ion channel function related to a colocalisation in close proximity to the Golgi apparatus.
Title: ROR?t+ cells selectively express redundant cation channels linked to the Golgi apparatus.

human TMEM176A and 176B protein levels are significantly elevated in lymphoma, but not in normal tissues
Title: Abnormal accumulation of human transmembrane (TMEM)-176A and 176B proteins is associated with cancer pathology.

The following TMEM176A gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TMEM176A cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu24795	NM_018487.3 Latest version!	Homo sapiens transmembrane protein 176A (TMEM176A), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu69395	XM_011516376.3 Latest version!	Homo sapiens transmembrane protein 176A (TMEM176A), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu69396	XM_011516377.2 Latest version!	Homo sapiens transmembrane protein 176A (TMEM176A), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu69397	XM_011516378.2 Latest version!	Homo sapiens transmembrane protein 176A (TMEM176A), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu105913	XM_024446824.1 Latest version!	Homo sapiens transmembrane protein 176A (TMEM176A), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
OHu97377	XM_017012393.1 Latest version!	Homo sapiens transmembrane protein 176A (TMEM176A), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OHu24795	NM_018487.2	Homo sapiens transmembrane protein 176A (TMEM176A), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu69395	XM_011516376.2	Homo sapiens transmembrane protein 176A (TMEM176A), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TMEM176A ( NM_018487.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_060957.2 Homo sapiens transmembrane protein 176A (TMEM176A), mRNA.

Price & Availability↑

CloneID	OHu24795
Clone ID Related Accession (Same CDS sequence)	NM_018487.2 , NM_018487.3
Accession Version	NM_018487.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 708bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-10
Organism	Homo sapiens(human)
Product	transmembrane protein 176A
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC008303.1 and BM663079.1. On Jul 9, 2003 this sequence version replaced NM_018487.1. ##Evidence-Data-START## Transcript exon combination :: BC008303.1, ERR279837.4541.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGGGAACAG CCGACAGTGA TGAGATGGCC CCGGAGGCCC CACAGCACAC CCACATCGAT 
GTGCACATCC ACCAGGAGTC TGCCCTGGCC AAGCTCCTGC TCACCTGCTG CTCTGCGCTG 
CGGCCCCGGG CCACCCAGGC CAGGGGCAGC AGCCGGCTGC TGGTGGCCTC GTGGGTGATG 
CAGATCGTGC TGGGGATCTT GAGTGCAGTC CTAGGAGGAT TTTTCTACAT CCGCGACTAC 
ACCCTCCTCG TCACCTCGGG AGCTGCCATC TGGACAGGGG CTGTGGCTGT GCTGGCTGGA 
GCTGCTGCCT TCATTTACGA GAAACGGGGT GGTACATACT GGGCCCTGCT GAGGACTCTG 
CTAACGCTGG CAGCTTTCTC CACAGCCATC GCTGCCCTCA AACTTTGGAA TGAAGATTTC 
CGATATGGCT ACTCTTATTA CAACAGTGCC TGCCGCATCT CCAGCTCGAG TGACTGGAAC 
ACTCCAGCCC CCACTCAGAG TCCAGAAGAA GTCAGAAGGC TACACCTATG TACCTCCTTC 
ATGGACATGC TGAAGGCCTT GTTCAGAACC CTTCAGGCCA TGCTCTTGGG TGTCTGGATT 
CTGCTGCTTC TGGCATCTCT GACCCCTCTG TGGCTGTACT GCTGGAGAAT GTTCCCAACC 
AAAGGGAAAA GAGACCAGAA GGAAATGTTG GAAGTGAGTG GAATCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060957.2
CDS	79..786
Translation	MGTADSDEMAPEAPQHTHIDVHIHQESALAKLLLTCCSALRPRATQARGSSRLLVASWVMQIVLGILSAVLGGFFYIRDYTLLVTSGAAIWTGAVAVLAGAAAFIYEKRGGTYWALLRTLLTLAAFSTAIAALKLWNEDFRYGYSYYNSACRISSSSDWNTPAPTQSPEEVRRLHLCTSFMDMLKALFRTLQAMLLGVWILLLLASLTPLWLYCWRMFPTKGKRDQKEMLEVSGI

Target ORF information:

RefSeq Version	NM_018487.2
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane protein 176A (TMEM176A), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018487.2

ORF Insert Sequence:

ATGGGAACAG CCGACAGTGA TGAGATGGCC CCGGAGGCCC CACAGCACAC CCACATCGAT 
GTGCACATCC ACCAGGAGTC TGCCCTGGCC AAGCTCCTGC TCACCTGCTG CTCTGCGCTG 
CGGCCCCGGG CCACCCAGGC CAGGGGCAGC AGCCGGCTGC TGGTGGCCTC GTGGGTGATG 
CAGATCGTGC TGGGGATCTT GAGTGCAGTC CTAGGAGGAT TTTTCTACAT CCGCGACTAC 
ACCCTCCTCG TCACCTCGGG AGCTGCCATC TGGACAGGGG CTGTGGCTGT GCTGGCTGGA 
GCTGCTGCCT TCATTTACGA GAAACGGGGT GGTACATACT GGGCCCTGCT GAGGACTCTG 
CTAACGCTGG CAGCTTTCTC CACAGCCATC GCTGCCCTCA AACTTTGGAA TGAAGATTTC 
CGATATGGCT ACTCTTATTA CAACAGTGCC TGCCGCATCT CCAGCTCGAG TGACTGGAAC 
ACTCCAGCCC CCACTCAGAG TCCAGAAGAA GTCAGAAGGC TACACCTATG TACCTCCTTC 
ATGGACATGC TGAAGGCCTT GTTCAGAACC CTTCAGGCCA TGCTCTTGGG TGTCTGGATT 
CTGCTGCTTC TGGCATCTCT GACCCCTCTG TGGCTGTACT GCTGGAGAAT GTTCCCAACC 
AAAGGGAAAA GAGACCAGAA GGAAATGTTG GAAGTGAGTG GAATCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMEM176A ( NM_018487.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_060957.2 Homo sapiens transmembrane protein 176A (TMEM176A), mRNA.

Price & Availability↑

CloneID	OHu24795
Clone ID Related Accession (Same CDS sequence)	NM_018487.2 , NM_018487.3
Accession Version	NM_018487.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 708bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-26
Organism	Homo sapiens(human)
Product	transmembrane protein 176A
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC008303.1. On Nov 23, 2018 this sequence version replaced NM_018487.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC008303.1, AF258340.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000004103.8/ ENSP00000004103.3 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGGAACAG CCGACAGTGA TGAGATGGCC CCGGAGGCCC CACAGCACAC CCACATCGAT 
GTGCACATCC ACCAGGAGTC TGCCCTGGCC AAGCTCCTGC TCACCTGCTG CTCTGCGCTG 
CGGCCCCGGG CCACCCAGGC CAGGGGCAGC AGCCGGCTGC TGGTGGCCTC GTGGGTGATG 
CAGATCGTGC TGGGGATCTT GAGTGCAGTC CTAGGAGGAT TTTTCTACAT CCGCGACTAC 
ACCCTCCTCG TCACCTCGGG AGCTGCCATC TGGACAGGGG CTGTGGCTGT GCTGGCTGGA 
GCTGCTGCCT TCATTTACGA GAAACGGGGT GGTACATACT GGGCCCTGCT GAGGACTCTG 
CTAACGCTGG CAGCTTTCTC CACAGCCATC GCTGCCCTCA AACTTTGGAA TGAAGATTTC 
CGATATGGCT ACTCTTATTA CAACAGTGCC TGCCGCATCT CCAGCTCGAG TGACTGGAAC 
ACTCCAGCCC CCACTCAGAG TCCAGAAGAA GTCAGAAGGC TACACCTATG TACCTCCTTC 
ATGGACATGC TGAAGGCCTT GTTCAGAACC CTTCAGGCCA TGCTCTTGGG TGTCTGGATT 
CTGCTGCTTC TGGCATCTCT GACCCCTCTG TGGCTGTACT GCTGGAGAAT GTTCCCAACC 
AAAGGGAAAA GAGACCAGAA GGAAATGTTG GAAGTGAGTG GAATCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060957.2
CDS	76..783
Translation	MGTADSDEMAPEAPQHTHIDVHIHQESALAKLLLTCCSALRPRATQARGSSRLLVASWVMQIVLGILSAVLGGFFYIRDYTLLVTSGAAIWTGAVAVLAGAAAFIYEKRGGTYWALLRTLLTLAAFSTAIAALKLWNEDFRYGYSYYNSACRISSSSDWNTPAPTQSPEEVRRLHLCTSFMDMLKALFRTLQAMLLGVWILLLLASLTPLWLYCWRMFPTKGKRDQKEMLEVSGI

Target ORF information:

RefSeq Version	NM_018487.3
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane protein 176A (TMEM176A), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018487.3

ORF Insert Sequence:

ATGGGAACAG CCGACAGTGA TGAGATGGCC CCGGAGGCCC CACAGCACAC CCACATCGAT 
GTGCACATCC ACCAGGAGTC TGCCCTGGCC AAGCTCCTGC TCACCTGCTG CTCTGCGCTG 
CGGCCCCGGG CCACCCAGGC CAGGGGCAGC AGCCGGCTGC TGGTGGCCTC GTGGGTGATG 
CAGATCGTGC TGGGGATCTT GAGTGCAGTC CTAGGAGGAT TTTTCTACAT CCGCGACTAC 
ACCCTCCTCG TCACCTCGGG AGCTGCCATC TGGACAGGGG CTGTGGCTGT GCTGGCTGGA 
GCTGCTGCCT TCATTTACGA GAAACGGGGT GGTACATACT GGGCCCTGCT GAGGACTCTG 
CTAACGCTGG CAGCTTTCTC CACAGCCATC GCTGCCCTCA AACTTTGGAA TGAAGATTTC 
CGATATGGCT ACTCTTATTA CAACAGTGCC TGCCGCATCT CCAGCTCGAG TGACTGGAAC 
ACTCCAGCCC CCACTCAGAG TCCAGAAGAA GTCAGAAGGC TACACCTATG TACCTCCTTC 
ATGGACATGC TGAAGGCCTT GTTCAGAACC CTTCAGGCCA TGCTCTTGGG TGTCTGGATT 
CTGCTGCTTC TGGCATCTCT GACCCCTCTG TGGCTGTACT GCTGGAGAAT GTTCCCAACC 
AAAGGGAAAA GAGACCAGAA GGAAATGTTG GAAGTGAGTG GAATCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMEM176A ( XM_011516376.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011514678.1 Homo sapiens transmembrane protein 176A (TMEM176A), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu69395
Clone ID Related Accession (Same CDS sequence)	XM_011516376.2 , XM_011516376.3
Accession Version	XM_011516376.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 759bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	transmembrane protein 176A isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011516376.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACACTCC AGGAAGGGGA CTGCAGAGGA AGCCAGACTG TGTCCCTGAC AATGGGAACA 
GCCGACAGTG ATGAGATGGC CCCGGAGGCC CCACAGCACA CCCACATCGA TGTGCACATC 
CACCAGGAGT CTGCCCTGGC CAAGCTCCTG CTCACCTGCT GCTCTGCGCT GCGGCCCCGG 
GCCACCCAGG CCAGGGGCAG CAGCCGGCTG CTGGTGGCCT CGTGGGTGAT GCAGATCGTG 
CTGGGGATCT TGAGTGCAGT CCTAGGAGGA TTTTTCTACA TCCGCGACTA CACCCTCCTC 
GTCACCTCGG GAGCTGCCAT CTGGACAGGG GCTGTGGCTG TGCTGGCTGG AGCTGCTGCC 
TTCATTTACG AGAAACGGGG TGGTACATAC TGGGCCCTGC TGAGGACTCT GCTAACGCTG 
GCAGCTTTCT CCACAGCCAT CGCTGCCCTC AAACTTTGGA ATGAAGATTT CCGATATGGC 
TACTCTTATT ACAACAGTGC CTGCCGCATC TCCAGCTCGA GTGACTGGAA CACTCCAGCC 
CCCACTCAGA GTCCAGAAGA AGTCAGAAGG CTACACCTAT GTACCTCCTT CATGGACATG 
CTGAAGGCCT TGTTCAGAAC CCTTCAGGCC ATGCTCTTGG GTGTCTGGAT TCTGCTGCTT 
CTGGCATCTC TGACCCCTCT GTGGCTGTAC TGCTGGAGAA TGTTCCCAAC CAAAGGGAAA 
AGAGACCAGA AGGAAATGTT GGAAGTGAGT GGAATCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011514678.1
CDS	163..921
Translation	MTLQEGDCRGSQTVSLTMGTADSDEMAPEAPQHTHIDVHIHQESALAKLLLTCCSALRPRATQARGSSRLLVASWVMQIVLGILSAVLGGFFYIRDYTLLVTSGAAIWTGAVAVLAGAAAFIYEKRGGTYWALLRTLLTLAAFSTAIAALKLWNEDFRYGYSYYNSACRISSSSDWNTPAPTQSPEEVRRLHLCTSFMDMLKALFRTLQAMLLGVWILLLLASLTPLWLYCWRMFPTKGKRDQKEMLEVSGI

Target ORF information:

RefSeq Version	XM_011516376.2
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane protein 176A (TMEM176A), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011516376.2

ORF Insert Sequence:

ATGACACTCC AGGAAGGGGA CTGCAGAGGA AGCCAGACTG TGTCCCTGAC AATGGGAACA 
GCCGACAGTG ATGAGATGGC CCCGGAGGCC CCACAGCACA CCCACATCGA TGTGCACATC 
CACCAGGAGT CTGCCCTGGC CAAGCTCCTG CTCACCTGCT GCTCTGCGCT GCGGCCCCGG 
GCCACCCAGG CCAGGGGCAG CAGCCGGCTG CTGGTGGCCT CGTGGGTGAT GCAGATCGTG 
CTGGGGATCT TGAGTGCAGT CCTAGGAGGA TTTTTCTACA TCCGCGACTA CACCCTCCTC 
GTCACCTCGG GAGCTGCCAT CTGGACAGGG GCTGTGGCTG TGCTGGCTGG AGCTGCTGCC 
TTCATTTACG AGAAACGGGG TGGTACATAC TGGGCCCTGC TGAGGACTCT GCTAACGCTG 
GCAGCTTTCT CCACAGCCAT CGCTGCCCTC AAACTTTGGA ATGAAGATTT CCGATATGGC 
TACTCTTATT ACAACAGTGC CTGCCGCATC TCCAGCTCGA GTGACTGGAA CACTCCAGCC 
CCCACTCAGA GTCCAGAAGA AGTCAGAAGG CTACACCTAT GTACCTCCTT CATGGACATG 
CTGAAGGCCT TGTTCAGAAC CCTTCAGGCC ATGCTCTTGG GTGTCTGGAT TCTGCTGCTT 
CTGGCATCTC TGACCCCTCT GTGGCTGTAC TGCTGGAGAA TGTTCCCAAC CAAAGGGAAA 
AGAGACCAGA AGGAAATGTT GGAAGTGAGT GGAATCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMEM176A ( XM_011516376.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_011514678.1 Homo sapiens transmembrane protein 176A (TMEM176A), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu69395
Clone ID Related Accession (Same CDS sequence)	XM_011516376.2 , XM_011516376.3
Accession Version	XM_011516376.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 759bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	transmembrane protein 176A isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011516376.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACACTCC AGGAAGGGGA CTGCAGAGGA AGCCAGACTG TGTCCCTGAC AATGGGAACA 
GCCGACAGTG ATGAGATGGC CCCGGAGGCC CCACAGCACA CCCACATCGA TGTGCACATC 
CACCAGGAGT CTGCCCTGGC CAAGCTCCTG CTCACCTGCT GCTCTGCGCT GCGGCCCCGG 
GCCACCCAGG CCAGGGGCAG CAGCCGGCTG CTGGTGGCCT CGTGGGTGAT GCAGATCGTG 
CTGGGGATCT TGAGTGCAGT CCTAGGAGGA TTTTTCTACA TCCGCGACTA CACCCTCCTC 
GTCACCTCGG GAGCTGCCAT CTGGACAGGG GCTGTGGCTG TGCTGGCTGG AGCTGCTGCC 
TTCATTTACG AGAAACGGGG TGGTACATAC TGGGCCCTGC TGAGGACTCT GCTAACGCTG 
GCAGCTTTCT CCACAGCCAT CGCTGCCCTC AAACTTTGGA ATGAAGATTT CCGATATGGC 
TACTCTTATT ACAACAGTGC CTGCCGCATC TCCAGCTCGA GTGACTGGAA CACTCCAGCC 
CCCACTCAGA GTCCAGAAGA AGTCAGAAGG CTACACCTAT GTACCTCCTT CATGGACATG 
CTGAAGGCCT TGTTCAGAAC CCTTCAGGCC ATGCTCTTGG GTGTCTGGAT TCTGCTGCTT 
CTGGCATCTC TGACCCCTCT GTGGCTGTAC TGCTGGAGAA TGTTCCCAAC CAAAGGGAAA 
AGAGACCAGA AGGAAATGTT GGAAGTGAGT GGAATCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011514678.1
CDS	354..1112
Translation	MTLQEGDCRGSQTVSLTMGTADSDEMAPEAPQHTHIDVHIHQESALAKLLLTCCSALRPRATQARGSSRLLVASWVMQIVLGILSAVLGGFFYIRDYTLLVTSGAAIWTGAVAVLAGAAAFIYEKRGGTYWALLRTLLTLAAFSTAIAALKLWNEDFRYGYSYYNSACRISSSSDWNTPAPTQSPEEVRRLHLCTSFMDMLKALFRTLQAMLLGVWILLLLASLTPLWLYCWRMFPTKGKRDQKEMLEVSGI

Target ORF information:

RefSeq Version	XM_011516376.3
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane protein 176A (TMEM176A), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011516376.3

ORF Insert Sequence:

ATGACACTCC AGGAAGGGGA CTGCAGAGGA AGCCAGACTG TGTCCCTGAC AATGGGAACA 
GCCGACAGTG ATGAGATGGC CCCGGAGGCC CCACAGCACA CCCACATCGA TGTGCACATC 
CACCAGGAGT CTGCCCTGGC CAAGCTCCTG CTCACCTGCT GCTCTGCGCT GCGGCCCCGG 
GCCACCCAGG CCAGGGGCAG CAGCCGGCTG CTGGTGGCCT CGTGGGTGAT GCAGATCGTG 
CTGGGGATCT TGAGTGCAGT CCTAGGAGGA TTTTTCTACA TCCGCGACTA CACCCTCCTC 
GTCACCTCGG GAGCTGCCAT CTGGACAGGG GCTGTGGCTG TGCTGGCTGG AGCTGCTGCC 
TTCATTTACG AGAAACGGGG TGGTACATAC TGGGCCCTGC TGAGGACTCT GCTAACGCTG 
GCAGCTTTCT CCACAGCCAT CGCTGCCCTC AAACTTTGGA ATGAAGATTT CCGATATGGC 
TACTCTTATT ACAACAGTGC CTGCCGCATC TCCAGCTCGA GTGACTGGAA CACTCCAGCC 
CCCACTCAGA GTCCAGAAGA AGTCAGAAGG CTACACCTAT GTACCTCCTT CATGGACATG 
CTGAAGGCCT TGTTCAGAAC CCTTCAGGCC ATGCTCTTGG GTGTCTGGAT TCTGCTGCTT 
CTGGCATCTC TGACCCCTCT GTGGCTGTAC TGCTGGAGAA TGTTCCCAAC CAAAGGGAAA 
AGAGACCAGA AGGAAATGTT GGAAGTGAGT GGAATCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMEM176A ( XM_011516377.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011514679.1 Homo sapiens transmembrane protein 176A (TMEM176A), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu69396
Clone ID Related Accession (Same CDS sequence)	XM_011516377.2
Accession Version	XM_011516377.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 729bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	transmembrane protein 176A isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011516377.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACACTCC AGGAAGGGGA CTGCAGAGGA AGCCAGACTG TGTCCCTGAC AATGGGAACA 
GCCGACAGTG ATGAGATGGC CCCGGAGGCC CCACAGCACA CCCACATCGA TGTGCACATC 
CACCAGGAGT CTGCCCTGGC CAAGCTCCTG CTCACCTGCT GCTCTGCGCT GCGGCCCCGG 
GCCACCCAGG CCAGGGGCAG CAGCCGGCTG CTGGTGGCCT CGTGGGTGAT GCAGATCGTG 
CTGGGGATCT TGAGTGCAGT CCTAGGAGGA TTTTTCTACA TCCGCGACTA CACCCTCCTC 
GTCACCTCGG GAGCTGCCAT CTGGACAGGG GCTGTGGCTG TGCTGGCTGG AGCTGCTGCC 
TTCATTTACG AGAAACGGGG TGGTACATAC TGGGCCCTGC TGAGGACTCT GCTAACGCTG 
GCAGCTTTCT CCACAGCCAT CGCTGCCCTC AAACTTTGGA ATGAAGATTT CCGATATGGC 
TACTCTTATT ACAACAGTGC CTGCCGCATC TCCAGCTCGA GTGACTGGAA CACTCCAGCC 
CCCACTCAGA GTCCAGAAGA AGTCAGAAGG CTACACCTAT GTACCTCCTT CATGGACATG 
CTGAAGGCCT TGTTCAGAAC CCTTCAGGCC ATGCTCTTGG GTGTCTGGAT TCTGCTGCTT 
CTGGCATCTC TGACCCCTCT GTGGCTGTAC TGCTGGAGAA TGTTCCCAAC CAAAGGGGTG 
AGTCCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011514679.1
CDS	166..894
Translation	MTLQEGDCRGSQTVSLTMGTADSDEMAPEAPQHTHIDVHIHQESALAKLLLTCCSALRPRATQARGSSRLLVASWVMQIVLGILSAVLGGFFYIRDYTLLVTSGAAIWTGAVAVLAGAAAFIYEKRGGTYWALLRTLLTLAAFSTAIAALKLWNEDFRYGYSYYNSACRISSSSDWNTPAPTQSPEEVRRLHLCTSFMDMLKALFRTLQAMLLGVWILLLLASLTPLWLYCWRMFPTKGVSP

Target ORF information:

RefSeq Version	XM_011516377.2
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane protein 176A (TMEM176A), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011516377.2

ORF Insert Sequence:

ATGACACTCC AGGAAGGGGA CTGCAGAGGA AGCCAGACTG TGTCCCTGAC AATGGGAACA 
GCCGACAGTG ATGAGATGGC CCCGGAGGCC CCACAGCACA CCCACATCGA TGTGCACATC 
CACCAGGAGT CTGCCCTGGC CAAGCTCCTG CTCACCTGCT GCTCTGCGCT GCGGCCCCGG 
GCCACCCAGG CCAGGGGCAG CAGCCGGCTG CTGGTGGCCT CGTGGGTGAT GCAGATCGTG 
CTGGGGATCT TGAGTGCAGT CCTAGGAGGA TTTTTCTACA TCCGCGACTA CACCCTCCTC 
GTCACCTCGG GAGCTGCCAT CTGGACAGGG GCTGTGGCTG TGCTGGCTGG AGCTGCTGCC 
TTCATTTACG AGAAACGGGG TGGTACATAC TGGGCCCTGC TGAGGACTCT GCTAACGCTG 
GCAGCTTTCT CCACAGCCAT CGCTGCCCTC AAACTTTGGA ATGAAGATTT CCGATATGGC 
TACTCTTATT ACAACAGTGC CTGCCGCATC TCCAGCTCGA GTGACTGGAA CACTCCAGCC 
CCCACTCAGA GTCCAGAAGA AGTCAGAAGG CTACACCTAT GTACCTCCTT CATGGACATG 
CTGAAGGCCT TGTTCAGAAC CCTTCAGGCC ATGCTCTTGG GTGTCTGGAT TCTGCTGCTT 
CTGGCATCTC TGACCCCTCT GTGGCTGTAC TGCTGGAGAA TGTTCCCAAC CAAAGGGGTG 
AGTCCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMEM176A ( XM_011516378.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011514680.1 Homo sapiens transmembrane protein 176A (TMEM176A), transcript variant X4, mRNA.

Price & Availability↑

CloneID	OHu69397
Clone ID Related Accession (Same CDS sequence)	XM_011516378.2
Accession Version	XM_011516378.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 648bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	transmembrane protein 176A isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011516378.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACACTCC AGGAAGGGGA CTGCAGAGGA AGCCAGACTG TGTCCCTGAC AATGGGAACA 
GCCGACAGTG ATGAGATGGC CCCGGAGGCC CCACAGCACA CCCACATCGA TGTGCACATC 
CACCAGGAGT CTGCCCTGGC CAAGCTCCTG CTCACCTGCT GCTCTGCGCT GCGGCCCCGG 
GCCACCCAGG CCAGGGGCAG CAGCCGGCTG CTGGTGGCCT CGTGGGTGAT GCAGATCGTG 
CTGGGGATCT TGAGTGCAGT CCTAGGAGGA TTTTTCTACA TCCGCGACTA CACCCTCCTC 
GTCACCTCGG GAGCTGCCAT CTGGACAGGG GCTGTGGCTG TGCTGGCTGG AGCTGCTGCC 
TTCATTTACG AGAAACGGGG TGGTACATAC TGGGCCCTGC TGAGGACTCT GCTAACGCTG 
GCAGCTTTCT CCACAGCCAT CGCTGCCCTC AAACTTTGGA ATGAAGATTT CCGATATGGC 
TACTCTTATT ACAACAGTGC CTGCCGCATC TCCAGCTCGA GTGACTGGAA CACTCCAGCC 
CCCACTCAGA GTCCAGAAGA AGTCAGAAGG CTACACCTAT GTACCTCCTT CATGGACATG 
CTGAAGAAAA GAGACCAGAA GGAAATGTTG GAAGTGAGTG GAATCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011514680.1
CDS	172..819
Translation	MTLQEGDCRGSQTVSLTMGTADSDEMAPEAPQHTHIDVHIHQESALAKLLLTCCSALRPRATQARGSSRLLVASWVMQIVLGILSAVLGGFFYIRDYTLLVTSGAAIWTGAVAVLAGAAAFIYEKRGGTYWALLRTLLTLAAFSTAIAALKLWNEDFRYGYSYYNSACRISSSSDWNTPAPTQSPEEVRRLHLCTSFMDMLKKRDQKEMLEVSGI

Target ORF information:

RefSeq Version	XM_011516378.2
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane protein 176A (TMEM176A), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011516378.2

ORF Insert Sequence:

ATGACACTCC AGGAAGGGGA CTGCAGAGGA AGCCAGACTG TGTCCCTGAC AATGGGAACA 
GCCGACAGTG ATGAGATGGC CCCGGAGGCC CCACAGCACA CCCACATCGA TGTGCACATC 
CACCAGGAGT CTGCCCTGGC CAAGCTCCTG CTCACCTGCT GCTCTGCGCT GCGGCCCCGG 
GCCACCCAGG CCAGGGGCAG CAGCCGGCTG CTGGTGGCCT CGTGGGTGAT GCAGATCGTG 
CTGGGGATCT TGAGTGCAGT CCTAGGAGGA TTTTTCTACA TCCGCGACTA CACCCTCCTC 
GTCACCTCGG GAGCTGCCAT CTGGACAGGG GCTGTGGCTG TGCTGGCTGG AGCTGCTGCC 
TTCATTTACG AGAAACGGGG TGGTACATAC TGGGCCCTGC TGAGGACTCT GCTAACGCTG 
GCAGCTTTCT CCACAGCCAT CGCTGCCCTC AAACTTTGGA ATGAAGATTT CCGATATGGC 
TACTCTTATT ACAACAGTGC CTGCCGCATC TCCAGCTCGA GTGACTGGAA CACTCCAGCC 
CCCACTCAGA GTCCAGAAGA AGTCAGAAGG CTACACCTAT GTACCTCCTT CATGGACATG 
CTGAAGAAAA GAGACCAGAA GGAAATGTTG GAAGTGAGTG GAATCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMEM176A ( XM_024446824.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024302592.1 Homo sapiens transmembrane protein 176A (TMEM176A), transcript variant X5, mRNA.

Price & Availability↑

CloneID	OHu105913
Clone ID Related Accession (Same CDS sequence)	XM_024446824.1
Accession Version	XM_024446824.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 597bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	transmembrane protein 176A isoform X5
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGAACAG CCGACAGTGA TGAGATGGCC CCGGAGGCCC CACAGCACAC CCACATCGAT 
GTGCACATCC ACCAGGAGTC TGCCCTGGCC AAGCTCCTGC TCACCTGCTG CTCTGCGCTG 
CGGCCCCGGG CCACCCAGGC CAGGGGCAGC AGCCGGCTGC TGGTGGCCTC GTGGGTGATG 
CAGATCGTGC TGGGGATCTT GAGTGCAGTC CTAGGAGGAT TTTTCTACAT CCGCGACTAC 
ACCCTCCTCG TCACCTCGGG AGCTGCCATC TGGACAGGGG CTGTGGCTGT GCTGGCTGGA 
GCTGCTGCCT TCATTTACGA GAAACGGGGT GGTACATACT GGGCCCTGCT GAGGACTCTG 
CTAACGCTGG CAGCTTTCTC CACAGCCATC GCTGCCCTCA AACTTTGGAA TGAAGATTTC 
CGATATGGCT ACTCTTATTA CAACAGTGCC TGCCGCATCT CCAGCTCGAG TGACTGGAAC 
ACTCCAGCCC CCACTCAGAG TCCAGAAGAA GTCAGAAGGC TACACCTATG TACCTCCTTC 
ATGGACATGC TGAAGAAAAG AGACCAGAAG GAAATGTTGG AAGTGAGTGG AATCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024302592.1
CDS	302..898
Translation	MGTADSDEMAPEAPQHTHIDVHIHQESALAKLLLTCCSALRPRATQARGSSRLLVASWVMQIVLGILSAVLGGFFYIRDYTLLVTSGAAIWTGAVAVLAGAAAFIYEKRGGTYWALLRTLLTLAAFSTAIAALKLWNEDFRYGYSYYNSACRISSSSDWNTPAPTQSPEEVRRLHLCTSFMDMLKKRDQKEMLEVSGI

Target ORF information:

RefSeq Version	XM_024446824.1
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane protein 176A (TMEM176A), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024446824.1

ORF Insert Sequence:

ATGGGAACAG CCGACAGTGA TGAGATGGCC CCGGAGGCCC CACAGCACAC CCACATCGAT 
GTGCACATCC ACCAGGAGTC TGCCCTGGCC AAGCTCCTGC TCACCTGCTG CTCTGCGCTG 
CGGCCCCGGG CCACCCAGGC CAGGGGCAGC AGCCGGCTGC TGGTGGCCTC GTGGGTGATG 
CAGATCGTGC TGGGGATCTT GAGTGCAGTC CTAGGAGGAT TTTTCTACAT CCGCGACTAC 
ACCCTCCTCG TCACCTCGGG AGCTGCCATC TGGACAGGGG CTGTGGCTGT GCTGGCTGGA 
GCTGCTGCCT TCATTTACGA GAAACGGGGT GGTACATACT GGGCCCTGCT GAGGACTCTG 
CTAACGCTGG CAGCTTTCTC CACAGCCATC GCTGCCCTCA AACTTTGGAA TGAAGATTTC 
CGATATGGCT ACTCTTATTA CAACAGTGCC TGCCGCATCT CCAGCTCGAG TGACTGGAAC 
ACTCCAGCCC CCACTCAGAG TCCAGAAGAA GTCAGAAGGC TACACCTATG TACCTCCTTC 
ATGGACATGC TGAAGAAAAG AGACCAGAAG GAAATGTTGG AAGTGAGTGG AATCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMEM176A ( XM_017012393.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016867882.1 Homo sapiens transmembrane protein 176A (TMEM176A), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu97377
Clone ID Related Accession (Same CDS sequence)	XM_017012393.1
Accession Version	XM_017012393.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 678bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	transmembrane protein 176A isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGAACAG CCGACAGTGA TGAGATGGCC CCGGAGGCCC CACAGCACAC CCACATCGAT 
GTGCACATCC ACCAGGAGTC TGCCCTGGCC AAGCTCCTGC TCACCTGCTG CTCTGCGCTG 
CGGCCCCGGG CCACCCAGGC CAGGGGCAGC AGCCGGCTGC TGGTGGCCTC GTGGGTGATG 
CAGATCGTGC TGGGGATCTT GAGTGCAGTC CTAGGAGGAT TTTTCTACAT CCGCGACTAC 
ACCCTCCTCG TCACCTCGGG AGCTGCCATC TGGACAGGGG CTGTGGCTGT GCTGGCTGGA 
GCTGCTGCCT TCATTTACGA GAAACGGGGT GGTACATACT GGGCCCTGCT GAGGACTCTG 
CTAACGCTGG CAGCTTTCTC CACAGCCATC GCTGCCCTCA AACTTTGGAA TGAAGATTTC 
CGATATGGCT ACTCTTATTA CAACAGTGCC TGCCGCATCT CCAGCTCGAG TGACTGGAAC 
ACTCCAGCCC CCACTCAGAG TCCAGAAGAA GTCAGAAGGC TACACCTATG TACCTCCTTC 
ATGGACATGC TGAAGGCCTT GTTCAGAACC CTTCAGGCCA TGCTCTTGGG TGTCTGGATT 
CTGCTGCTTC TGGCATCTCT GACCCCTCTG TGGCTGTACT GCTGGAGAAT GTTCCCAACC 
AAAGGGGTGA GTCCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016867882.1
CDS	302..979
Translation	MGTADSDEMAPEAPQHTHIDVHIHQESALAKLLLTCCSALRPRATQARGSSRLLVASWVMQIVLGILSAVLGGFFYIRDYTLLVTSGAAIWTGAVAVLAGAAAFIYEKRGGTYWALLRTLLTLAAFSTAIAALKLWNEDFRYGYSYYNSACRISSSSDWNTPAPTQSPEEVRRLHLCTSFMDMLKALFRTLQAMLLGVWILLLLASLTPLWLYCWRMFPTKGVSP

Target ORF information:

RefSeq Version	XM_017012393.1
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane protein 176A (TMEM176A), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017012393.1

ORF Insert Sequence:

ATGGGAACAG CCGACAGTGA TGAGATGGCC CCGGAGGCCC CACAGCACAC CCACATCGAT 
GTGCACATCC ACCAGGAGTC TGCCCTGGCC AAGCTCCTGC TCACCTGCTG CTCTGCGCTG 
CGGCCCCGGG CCACCCAGGC CAGGGGCAGC AGCCGGCTGC TGGTGGCCTC GTGGGTGATG 
CAGATCGTGC TGGGGATCTT GAGTGCAGTC CTAGGAGGAT TTTTCTACAT CCGCGACTAC 
ACCCTCCTCG TCACCTCGGG AGCTGCCATC TGGACAGGGG CTGTGGCTGT GCTGGCTGGA 
GCTGCTGCCT TCATTTACGA GAAACGGGGT GGTACATACT GGGCCCTGCT GAGGACTCTG 
CTAACGCTGG CAGCTTTCTC CACAGCCATC GCTGCCCTCA AACTTTGGAA TGAAGATTTC 
CGATATGGCT ACTCTTATTA CAACAGTGCC TGCCGCATCT CCAGCTCGAG TGACTGGAAC 
ACTCCAGCCC CCACTCAGAG TCCAGAAGAA GTCAGAAGGC TACACCTATG TACCTCCTTC 
ATGGACATGC TGAAGGCCTT GTTCAGAACC CTTCAGGCCA TGCTCTTGGG TGTCTGGATT 
CTGCTGCTTC TGGCATCTCT GACCCCTCTG TGGCTGTACT GCTGGAGAAT GTTCCCAACC 
AAAGGGGTGA GTCCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Exome sequences of multiplex, multigenerational families reveal schizophrenia risk loci with potential implications for neurocognitive performance.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics174(8)817-827(2017 Dec)
Kos MZ,Carless MA,Peralta J,Curran JE,Quillen EE,Almeida M,Blackburn A,Blondell L,Roalf DR,Pogue-Geile MF,Gur RC,G?ring HHH,Nimgaonkar VL,Gur RE,Almasy L

Methylation of TMEM176A is an independent prognostic marker and is involved in human colorectal cancer development.
Epigenetics12(7)575-583(2017 07)
Gao D,Han Y,Yang Y,Herman JG,Linghu E,Zhan Q,Fuks F,Lu ZJ,Guo M

ROR?t+ cells selectively express redundant cation channels linked to the Golgi apparatus.
Scientific reports623682(2016 Mar)
Drujont L,Lemoine A,Moreau A,Bienvenu G,Lancien M,Cens T,Guillot F,B?riou G,Bouchet-Delbos L,Fehling HJ,Chiffoleau E,Nicot AB,Charnet P,Martin JC,Josien R,Cuturi MC,Louvet C

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TMEM176A cDNA ORF clone, Homo sapiens(human)

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gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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