PPP5C cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PPP5C
Entrez Gene ID	5536
Full Name	protein phosphatase 5 catalytic subunit
Synonyms	PP5,PPP5,PPT
General protein information	Preferred Names protein phosphatase 5 catalytic subunit Names serine/threonine-protein phosphatase 5 PP-T protein phosphatase T
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19q13.32
Summary	This gene encodes a serine/threonine phosphatase which is a member of the protein phosphatase catalytic subunit family. Proteins in this family participate in pathways regulated by reversible phosphorylation at serine and threonine residues; many of these pathways are involved in the regulation of cell growth and differentiation. The product of this gene has been shown to participate in signaling pathways in response to hormones or cellular stress, and elevated levels of this protein may be associated with breast cancer development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2011].
Disorder MIM:	600658

mRNA and Protein(s)

mRNA	Protein	Name
NM_001204284.2	NP_001191213.1	serine/threonine-protein phosphatase 5 isoform 2
NM_001204284.1	NP_001191213.1	serine/threonine-protein phosphatase 5 isoform 2
XM_017026935.1	XP_016882424.1	serine/threonine-protein phosphatase 5 isoform X1
NM_006247.3	NP_006238.1	serine/threonine-protein phosphatase 5 isoform 1
NM_006247.4	NP_006238.1	serine/threonine-protein phosphatase 5 isoform 1
XM_017026935.2	XP_016882424.1	serine/threonine-protein phosphatase 5 isoform X1

Pathways from BioSystems

Homologies

Kluyveromyces lactis	KLLA0B10912g	XP_452014.1
Eremothecium gossypii	AGOS_AAR083C	NP_982624.2
	PPP5C	XP_001111749.1
Canis lupus familiaris (dog)	PPP5C	XP_005616926.1
Rattus norvegicus (Norway rat)	Ppp5c	NP_113917.1
Drosophila melanogaster (fruit fly)	PpD3	NP_524946.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP004151	XP_313034.5
Pan troglodytes (chimpanzee)	PPP5C	XP_512768.2
Mus musculus (house mouse)	Ppp5c	NP_035285.2
Danio rerio (zebrafish)	ppp5c	NP_001014372.2
Caenorhabditis elegans (roundworm)	pph-5	NP_001256849.1
Saccharomyces cerevisiae (baker's yeast)	PPT1	NP_011639.3
Schizosaccharomyces pombe (fission yeast)	SPBC3F6.01c	NP_596740.1
Neurospora crassa	NCU01433	XP_955993.1
Oryza sativa (rice)	Os05g0204900	NP_001054892.1
Bos taurus (cattle)	PPP5C	NP_001179178.1
Magnaporthe oryzae (rice blast fungus)	MGG_06941	XP_003709681.1
Xenopus tropicalis (tropical clawed frog)	ppp5c	NP_001007891.1
Homo sapiens (human)	PPP5C	NP_006238.1
Arabidopsis thaliana (thale cress)	PP5.2	NP_565985.1

Gene Ontology
Bibliography

Related articles in PubMed

Protein phosphatase 5 regulates titin phosphorylation and function at a sarcomere-associated mechanosensor complex in cardiomyocytes.
Krysiak J, Unger A, Beckendorf L, Hamdani N, von Frieling-Salewsky M, Redfield MM, Dos Remedios CG, Sheikh F, Gergs U, Boknik P, Linke WA
Nature communications9(1)262(2018 Jan)

Tumor suppressor Tsc1 is a new Hsp90 co-chaperone that facilitates folding of kinase and non-kinase clients.
Woodford MR, Sager RA, Marris E, Dunn DM, Blanden AR, Murphy RL, Rensing N, Shapiro O, Panaretou B, Prodromou C, Loh SN, Gutmann DH, Bourboulia D, Bratslavsky G, Wong M, Mollapour M
The EMBO journal36(24)3650-3665(2017 12)

Disruption of serine/threonine protein phosphatase 5 inhibits tumorigenesis of urinary bladder cancer cells.
Chen M, Lv JM, Ye JQ, Cui XG, Qu FJ, Chen L, Liu X, Pan XW, Li L, Huang H, Yang QW, Chen J, Wang LH, Gao Y, Xu DF
International journal of oncology51(1)39-48(2017 Jul)

Roles of tau protein in health and disease.
Guo T, Noble W, Hanger DP
Acta neuropathologica133(5)665-704(2017 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

PP5-dependent impairment of GRalpha function represents a novel mechanism driving GC insensitivity in ASM in severe asthma.
Title: Protein phosphatase 5 mediates corticosteroid insensitivity in airway smooth muscle in patients with severe asthma.

Our results showed 1) a critical role for PP5 in cytokine-induced resistance to GC-mediated eosinophil death, 2) supported the dependence of GCR phosphorylation on PP5 activity, and 3) revealed that PP5 is a target of the lipoxin A4-induced pathway countering cytokine-induced resistance to GCs in eosinophils.
Title: Cytokine-Induced Glucocorticoid Resistance from Eosinophil Activation: Protein Phosphatase 5 Modulation of Glucocorticoid Receptor Phosphorylation and Signaling.

Measles Virus Infection Inactivates Cellular Protein Phosphatase 5 with Consequent Suppression of Sp1 and c-Myc Activities.
Title: Measles Virus Infection Inactivates Cellular Protein Phosphatase 5 with Consequent Suppression of Sp1 and c-Myc Activities.

PPP5C could be essential for glioma cell growth.
Title: Serine/Threonine Protein Phosphatase-5 Accelerates Cell Growth and Migration in Human Glioma.

We demonstrate for the first time that PPP5C is essential for growth of HCC cells, which suggests that inhibition of PPP5C by RNAi may be a potential therapeutic strategy for the treatment of hepatocellular carcinoma.
Title: Knockdown of PPP5C inhibits growth of hepatocellular carcinoma cells in vitro.

The following PPP5C gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PPP5C cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu23127	NM_006247.4 Latest version!	Homo sapiens protein phosphatase 5 catalytic subunit (PPP5C), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu15715	NM_001204284.2 Latest version!	Homo sapiens protein phosphatase 5 catalytic subunit (PPP5C), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu88546	XM_017026935.2 Latest version!	Homo sapiens protein phosphatase 5 catalytic subunit (PPP5C), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
View Old Accession Versions >>
OHu15715	NM_001204284.1	Homo sapiens protein phosphatase 5 catalytic subunit (PPP5C), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu23127	NM_006247.3	Homo sapiens protein phosphatase 5 catalytic subunit (PPP5C), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu88546	XM_017026935.1	Homo sapiens protein phosphatase 5 catalytic subunit (PPP5C), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PPP5C ( NM_006247.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_006238.1 Homo sapiens protein phosphatase 5 catalytic subunit (PPP5C), transcript variant 1, mRNA.

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CloneID	OHu23127
Clone ID Related Accession (Same CDS sequence)	NM_006247.3 , NM_006247.4
Accession Version	NM_006247.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1500bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Homo sapiens(human)
Product	serine/threonine-protein phosphatase 5 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA545760.1, BC001970.1 and AC007193.1. This sequence is a reference standard in the RefSeqGene project. On Feb 24, 2011 this sequence version replaced NM_006247.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer protein (isoform 1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC001970.1, SRR1163657.119374.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGATGG CGGAGGGCGA GAGGACTGAG TGTGCTGAGC CCCCCCGGGA CGAACCCCCG 
GCTGATGGAG CTCTGAAGCG GGCAGAGGAG CTCAAGACTC AGGCCAATGA CTACTTCAAA 
GCCAAGGACT ACGAGAACGC CATCAAGTTC TACAGCCAGG CCATCGAGCT GAACCCCAGC 
AATGCCATCT ACTATGGCAA CCGCAGCCTG GCCTACCTGC GCACTGAGTG CTATGGCTAC 
GCGCTGGGAG ACGCCACGCG GGCCATTGAG CTGGACAAGA AGTACATCAA GGGTTATTAC 
CGCCGGGCTG CCAGCAACAT GGCACTGGGC AAGTTCCGGG CCGCGCTGCG AGACTACGAG 
ACGGTGGTCA AGGTGAAGCC CCATGACAAG GATGCCAAAA TGAAATACCA GGAGTGCAAC 
AAGATCGTGA AGCAGAAGGC CTTTGAGCGG GCCATCGCGG GCGACGAGCA CAAGCGCTCC 
GTGGTGGACT CGCTGGACAT CGAGAGCATG ACCATTGAGG ATGAGTACAG CGGACCCAAG 
CTTGAAGACG GCAAAGTGAC AATCAGTTTC ATGAAGGAGC TCATGCAGTG GTACAAGGAC 
CAGAAGAAAC TGCACCGGAA ATGTGCCTAC CAGATTCTGG TACAGGTCAA AGAGGTCCTC 
TCCAAGCTGA GCACGCTCGT GGAAACCACA CTCAAAGAGA CAGAGAAGAT TACAGTATGT 
GGGGACACCC ATGGCCAGTT CTATGACCTC CTCAACATAT TCGAGCTCAA CGGTTTACCC 
TCGGAGACCA ACCCCTATAT ATTTAATGGT GACTTTGTGG ACCGAGGCTC CTTCTCTGTA 
GAAGTGATCC TCACCCTTTT CGGCTTCAAG CTCCTGTACC CAGATCACTT TCACCTCCTT 
CGAGGCAACC ACGAGACAGA CAACATGAAC CAGATCTACG GTTTCGAGGG TGAGGTGAAG 
GCCAAGTACA CAGCCCAGAT GTACGAGCTC TTTAGCGAGG TGTTCGAGTG GCTCCCGTTG 
GCCCAGTGCA TCAACGGCAA AGTGCTGATC ATGCACGGAG GCCTGTTCAG TGAAGACGGT 
GTCACCCTGG ATGACATCCG GAAAATTGAG CGGAATCGAC AACCCCCAGA TTCAGGGCCC 
ATGTGTGACC TGCTCTGGTC AGATCCACAG CCACAGAACG GGCGCTCGAT CAGCAAGCGG 
GGCGTGAGCT GTCAGTTTGG GCCTGACGTC ACCAAGGCCT TCTTGGAAGA GAACAACCTG 
GACTATATCA TCCGCAGCCA CGAAGTCAAG GCCGAGGGCT ACGAGGTGGC TCACGGAGGC 
CGCTGTGTCA CCGTCTTCTC TGCCCCCAAC TACTGCGACC AGATGGGGAA CAAAGCCTCC 
TACATCCACC TCCAGGGCTC TGACCTACGG CCTCAGTTCC ACCAGTTCAC AGCAGTGCCT 
CATCCCAACG TCAAGCCCAT GGCCTATGCC AACACGCTGC TGCAGCTAGG AATGATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006238.1
CDS	104..1603
Translation	MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQLGMM

Target ORF information:

RefSeq Version	NM_006247.3
Organism	Homo sapiens(human)
Definition	Homo sapiens protein phosphatase 5 catalytic subunit (PPP5C), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006247.3

ORF Insert Sequence:

ATGGCGATGG CGGAGGGCGA GAGGACTGAG TGTGCTGAGC CCCCCCGGGA CGAACCCCCG 
GCTGATGGAG CTCTGAAGCG GGCAGAGGAG CTCAAGACTC AGGCCAATGA CTACTTCAAA 
GCCAAGGACT ACGAGAACGC CATCAAGTTC TACAGCCAGG CCATCGAGCT GAACCCCAGC 
AATGCCATCT ACTATGGCAA CCGCAGCCTG GCCTACCTGC GCACTGAGTG CTATGGCTAC 
GCGCTGGGAG ACGCCACGCG GGCCATTGAG CTGGACAAGA AGTACATCAA GGGTTATTAC 
CGCCGGGCTG CCAGCAACAT GGCACTGGGC AAGTTCCGGG CCGCGCTGCG AGACTACGAG 
ACGGTGGTCA AGGTGAAGCC CCATGACAAG GATGCCAAAA TGAAATACCA GGAGTGCAAC 
AAGATCGTGA AGCAGAAGGC CTTTGAGCGG GCCATCGCGG GCGACGAGCA CAAGCGCTCC 
GTGGTGGACT CGCTGGACAT CGAGAGCATG ACCATTGAGG ATGAGTACAG CGGACCCAAG 
CTTGAAGACG GCAAAGTGAC AATCAGTTTC ATGAAGGAGC TCATGCAGTG GTACAAGGAC 
CAGAAGAAAC TGCACCGGAA ATGTGCCTAC CAGATTCTGG TACAGGTCAA AGAGGTCCTC 
TCCAAGCTGA GCACGCTCGT GGAAACCACA CTCAAAGAGA CAGAGAAGAT TACAGTATGT 
GGGGACACCC ATGGCCAGTT CTATGACCTC CTCAACATAT TCGAGCTCAA CGGTTTACCC 
TCGGAGACCA ACCCCTATAT ATTTAATGGT GACTTTGTGG ACCGAGGCTC CTTCTCTGTA 
GAAGTGATCC TCACCCTTTT CGGCTTCAAG CTCCTGTACC CAGATCACTT TCACCTCCTT 
CGAGGCAACC ACGAGACAGA CAACATGAAC CAGATCTACG GTTTCGAGGG TGAGGTGAAG 
GCCAAGTACA CAGCCCAGAT GTACGAGCTC TTTAGCGAGG TGTTCGAGTG GCTCCCGTTG 
GCCCAGTGCA TCAACGGCAA AGTGCTGATC ATGCACGGAG GCCTGTTCAG TGAAGACGGT 
GTCACCCTGG ATGACATCCG GAAAATTGAG CGGAATCGAC AACCCCCAGA TTCAGGGCCC 
ATGTGTGACC TGCTCTGGTC AGATCCACAG CCACAGAACG GGCGCTCGAT CAGCAAGCGG 
GGCGTGAGCT GTCAGTTTGG GCCTGACGTC ACCAAGGCCT TCTTGGAAGA GAACAACCTG 
GACTATATCA TCCGCAGCCA CGAAGTCAAG GCCGAGGGCT ACGAGGTGGC TCACGGAGGC 
CGCTGTGTCA CCGTCTTCTC TGCCCCCAAC TACTGCGACC AGATGGGGAA CAAAGCCTCC 
TACATCCACC TCCAGGGCTC TGACCTACGG CCTCAGTTCC ACCAGTTCAC AGCAGTGCCT 
CATCCCAACG TCAAGCCCAT GGCCTATGCC AACACGCTGC TGCAGCTAGG AATGATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PPP5C ( NM_006247.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_006238.1 Homo sapiens protein phosphatase 5 catalytic subunit (PPP5C), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu23127
Clone ID Related Accession (Same CDS sequence)	NM_006247.3 , NM_006247.4
Accession Version	NM_006247.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1500bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-25
Organism	Homo sapiens(human)
Product	serine/threonine-protein phosphatase 5 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC001970.1 and AC007193.1. This sequence is a reference standard in the RefSeqGene project. On May 17, 2019 this sequence version replaced NM_006247.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer protein (isoform 1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK223222.1, SRR7410570.655620.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000012443.9/ ENSP00000012443.4 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGATGG CGGAGGGCGA GAGGACTGAG TGTGCTGAGC CCCCCCGGGA CGAACCCCCG 
GCTGATGGAG CTCTGAAGCG GGCAGAGGAG CTCAAGACTC AGGCCAATGA CTACTTCAAA 
GCCAAGGACT ACGAGAACGC CATCAAGTTC TACAGCCAGG CCATCGAGCT GAACCCCAGC 
AATGCCATCT ACTATGGCAA CCGCAGCCTG GCCTACCTGC GCACTGAGTG CTATGGCTAC 
GCGCTGGGAG ACGCCACGCG GGCCATTGAG CTGGACAAGA AGTACATCAA GGGTTATTAC 
CGCCGGGCTG CCAGCAACAT GGCACTGGGC AAGTTCCGGG CCGCGCTGCG AGACTACGAG 
ACGGTGGTCA AGGTGAAGCC CCATGACAAG GATGCCAAAA TGAAATACCA GGAGTGCAAC 
AAGATCGTGA AGCAGAAGGC CTTTGAGCGG GCCATCGCGG GCGACGAGCA CAAGCGCTCC 
GTGGTGGACT CGCTGGACAT CGAGAGCATG ACCATTGAGG ATGAGTACAG CGGACCCAAG 
CTTGAAGACG GCAAAGTGAC AATCAGTTTC ATGAAGGAGC TCATGCAGTG GTACAAGGAC 
CAGAAGAAAC TGCACCGGAA ATGTGCCTAC CAGATTCTGG TACAGGTCAA AGAGGTCCTC 
TCCAAGCTGA GCACGCTCGT GGAAACCACA CTCAAAGAGA CAGAGAAGAT TACAGTATGT 
GGGGACACCC ATGGCCAGTT CTATGACCTC CTCAACATAT TCGAGCTCAA CGGTTTACCC 
TCGGAGACCA ACCCCTATAT ATTTAATGGT GACTTTGTGG ACCGAGGCTC CTTCTCTGTA 
GAAGTGATCC TCACCCTTTT CGGCTTCAAG CTCCTGTACC CAGATCACTT TCACCTCCTT 
CGAGGCAACC ACGAGACAGA CAACATGAAC CAGATCTACG GTTTCGAGGG TGAGGTGAAG 
GCCAAGTACA CAGCCCAGAT GTACGAGCTC TTTAGCGAGG TGTTCGAGTG GCTCCCGTTG 
GCCCAGTGCA TCAACGGCAA AGTGCTGATC ATGCACGGAG GCCTGTTCAG TGAAGACGGT 
GTCACCCTGG ATGACATCCG GAAAATTGAG CGGAATCGAC AACCCCCAGA TTCAGGGCCC 
ATGTGTGACC TGCTCTGGTC AGATCCACAG CCACAGAACG GGCGCTCGAT CAGCAAGCGG 
GGCGTGAGCT GTCAGTTTGG GCCTGACGTC ACCAAGGCCT TCTTGGAAGA GAACAACCTG 
GACTATATCA TCCGCAGCCA CGAAGTCAAG GCCGAGGGCT ACGAGGTGGC TCACGGAGGC 
CGCTGTGTCA CCGTCTTCTC TGCCCCCAAC TACTGCGACC AGATGGGGAA CAAAGCCTCC 
TACATCCACC TCCAGGGCTC TGACCTACGG CCTCAGTTCC ACCAGTTCAC AGCAGTGCCT 
CATCCCAACG TCAAGCCCAT GGCCTATGCC AACACGCTGC TGCAGCTAGG AATGATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_006238.1
CDS	11..1510
Translation	MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQLGMM

Target ORF information:

RefSeq Version	NM_006247.4
Organism	Homo sapiens(human)
Definition	Homo sapiens protein phosphatase 5 catalytic subunit (PPP5C), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006247.4

ORF Insert Sequence:

ATGGCGATGG CGGAGGGCGA GAGGACTGAG TGTGCTGAGC CCCCCCGGGA CGAACCCCCG 
GCTGATGGAG CTCTGAAGCG GGCAGAGGAG CTCAAGACTC AGGCCAATGA CTACTTCAAA 
GCCAAGGACT ACGAGAACGC CATCAAGTTC TACAGCCAGG CCATCGAGCT GAACCCCAGC 
AATGCCATCT ACTATGGCAA CCGCAGCCTG GCCTACCTGC GCACTGAGTG CTATGGCTAC 
GCGCTGGGAG ACGCCACGCG GGCCATTGAG CTGGACAAGA AGTACATCAA GGGTTATTAC 
CGCCGGGCTG CCAGCAACAT GGCACTGGGC AAGTTCCGGG CCGCGCTGCG AGACTACGAG 
ACGGTGGTCA AGGTGAAGCC CCATGACAAG GATGCCAAAA TGAAATACCA GGAGTGCAAC 
AAGATCGTGA AGCAGAAGGC CTTTGAGCGG GCCATCGCGG GCGACGAGCA CAAGCGCTCC 
GTGGTGGACT CGCTGGACAT CGAGAGCATG ACCATTGAGG ATGAGTACAG CGGACCCAAG 
CTTGAAGACG GCAAAGTGAC AATCAGTTTC ATGAAGGAGC TCATGCAGTG GTACAAGGAC 
CAGAAGAAAC TGCACCGGAA ATGTGCCTAC CAGATTCTGG TACAGGTCAA AGAGGTCCTC 
TCCAAGCTGA GCACGCTCGT GGAAACCACA CTCAAAGAGA CAGAGAAGAT TACAGTATGT 
GGGGACACCC ATGGCCAGTT CTATGACCTC CTCAACATAT TCGAGCTCAA CGGTTTACCC 
TCGGAGACCA ACCCCTATAT ATTTAATGGT GACTTTGTGG ACCGAGGCTC CTTCTCTGTA 
GAAGTGATCC TCACCCTTTT CGGCTTCAAG CTCCTGTACC CAGATCACTT TCACCTCCTT 
CGAGGCAACC ACGAGACAGA CAACATGAAC CAGATCTACG GTTTCGAGGG TGAGGTGAAG 
GCCAAGTACA CAGCCCAGAT GTACGAGCTC TTTAGCGAGG TGTTCGAGTG GCTCCCGTTG 
GCCCAGTGCA TCAACGGCAA AGTGCTGATC ATGCACGGAG GCCTGTTCAG TGAAGACGGT 
GTCACCCTGG ATGACATCCG GAAAATTGAG CGGAATCGAC AACCCCCAGA TTCAGGGCCC 
ATGTGTGACC TGCTCTGGTC AGATCCACAG CCACAGAACG GGCGCTCGAT CAGCAAGCGG 
GGCGTGAGCT GTCAGTTTGG GCCTGACGTC ACCAAGGCCT TCTTGGAAGA GAACAACCTG 
GACTATATCA TCCGCAGCCA CGAAGTCAAG GCCGAGGGCT ACGAGGTGGC TCACGGAGGC 
CGCTGTGTCA CCGTCTTCTC TGCCCCCAAC TACTGCGACC AGATGGGGAA CAAAGCCTCC 
TACATCCACC TCCAGGGCTC TGACCTACGG CCTCAGTTCC ACCAGTTCAC AGCAGTGCCT 
CATCCCAACG TCAAGCCCAT GGCCTATGCC AACACGCTGC TGCAGCTAGG AATGATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PPP5C ( NM_001204284.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001191213.1 Homo sapiens protein phosphatase 5 catalytic subunit (PPP5C), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu15715
Clone ID Related Accession (Same CDS sequence)	NM_001204284.2 , NM_001204284.1
Accession Version	NM_001204284.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1434bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-28
Organism	Homo sapiens(human)
Product	serine/threonine-protein phosphatase 5 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA545760.1 and AC007193.1. On Jun 1, 2019 this sequence version replaced NM_001204284.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting protein (isoform 2) is shorter compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR7410570.655622.1, SRR1803614.42831.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGATGG CGGAGGGCGA GAGGACTGAG TGTGCTGAGC CCCCCCGGGA CGAACCCCCG 
GCTGATGGAG CTCTGAAGCG GGCAGAGGAG CTCAAGACTC AGGCCAATGA CTACTTCAAA 
GCCAAGGACT ACGAGAACGC CATCAAGTTC TACAGCCAGG CCATCGAGCT GAACCCCAGC 
AATGCCATCT ACTATGGCAA CCGCAGCCTG GCCTACCTGC GCACTGAGTG CTATGGCTAC 
GCGCTGGGAG ACGCCACGCG GGCCATTGAG CTGGACAAGA AGTACATCAA GGGTTATTAC 
CGCCGGGCTG CCAGCAACAT GGCACTGGGC AAGTTCCGGG CCGCGCTGCG AGACTACGAG 
ACGGTGGTCA AGGTGAAGCC CCATGACAAG GATGCCAAAA TGAAATACCA GGAGTGCAAC 
AAGATCGTGA AGCAGAAGGC CTTTGAGCGG GCCATCGCGG GCGACGAGCA CAAGCGCTCC 
GTGGTGGACT CGCTGGACAT CGAGAGCATG ACCATTGAGG ATGAGTACAG CGGACCCAAG 
CTTGAAGACG GCAAAGTGAC AATCAGTTTC ATGAAGGAGC TCATGCAGTG GTACAAGGAC 
CAGAAGAAAC TGCACCGGAA ATGTGCCTAC CAGACAGAGA AGATTACAGT ATGTGGGGAC 
ACCCATGGCC AGTTCTATGA CCTCCTCAAC ATATTCGAGC TCAACGGTTT ACCCTCGGAG 
ACCAACCCCT ATATATTTAA TGGTGACTTT GTGGACCGAG GCTCCTTCTC TGTAGAAGTG 
ATCCTCACCC TTTTCGGCTT CAAGCTCCTG TACCCAGATC ACTTTCACCT CCTTCGAGGC 
AACCACGAGA CAGACAACAT GAACCAGATC TACGGTTTCG AGGGTGAGGT GAAGGCCAAG 
TACACAGCCC AGATGTACGA GCTCTTTAGC GAGGTGTTCG AGTGGCTCCC GTTGGCCCAG 
TGCATCAACG GCAAAGTGCT GATCATGCAC GGAGGCCTGT TCAGTGAAGA CGGTGTCACC 
CTGGATGACA TCCGGAAAAT TGAGCGGAAT CGACAACCCC CAGATTCAGG GCCCATGTGT 
GACCTGCTCT GGTCAGATCC ACAGCCACAG AACGGGCGCT CGATCAGCAA GCGGGGCGTG 
AGCTGTCAGT TTGGGCCTGA CGTCACCAAG GCCTTCTTGG AAGAGAACAA CCTGGACTAT 
ATCATCCGCA GCCACGAAGT CAAGGCCGAG GGCTACGAGG TGGCTCACGG AGGCCGCTGT 
GTCACCGTCT TCTCTGCCCC CAACTACTGC GACCAGATGG GGAACAAAGC CTCCTACATC 
CACCTCCAGG GCTCTGACCT ACGGCCTCAG TTCCACCAGT TCACAGCAGT GCCTCATCCC 
AACGTCAAGC CCATGGCCTA TGCCAACACG CTGCTGCAGC TAGGAATGAT GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001191213.1
CDS	11..1444
Translation	MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQTEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQLGMM

Target ORF information:

RefSeq Version	NM_001204284.2
Organism	Homo sapiens(human)
Definition	Homo sapiens protein phosphatase 5 catalytic subunit (PPP5C), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001204284.2

ORF Insert Sequence:

ATGGCGATGG CGGAGGGCGA GAGGACTGAG TGTGCTGAGC CCCCCCGGGA CGAACCCCCG 
GCTGATGGAG CTCTGAAGCG GGCAGAGGAG CTCAAGACTC AGGCCAATGA CTACTTCAAA 
GCCAAGGACT ACGAGAACGC CATCAAGTTC TACAGCCAGG CCATCGAGCT GAACCCCAGC 
AATGCCATCT ACTATGGCAA CCGCAGCCTG GCCTACCTGC GCACTGAGTG CTATGGCTAC 
GCGCTGGGAG ACGCCACGCG GGCCATTGAG CTGGACAAGA AGTACATCAA GGGTTATTAC 
CGCCGGGCTG CCAGCAACAT GGCACTGGGC AAGTTCCGGG CCGCGCTGCG AGACTACGAG 
ACGGTGGTCA AGGTGAAGCC CCATGACAAG GATGCCAAAA TGAAATACCA GGAGTGCAAC 
AAGATCGTGA AGCAGAAGGC CTTTGAGCGG GCCATCGCGG GCGACGAGCA CAAGCGCTCC 
GTGGTGGACT CGCTGGACAT CGAGAGCATG ACCATTGAGG ATGAGTACAG CGGACCCAAG 
CTTGAAGACG GCAAAGTGAC AATCAGTTTC ATGAAGGAGC TCATGCAGTG GTACAAGGAC 
CAGAAGAAAC TGCACCGGAA ATGTGCCTAC CAGACAGAGA AGATTACAGT ATGTGGGGAC 
ACCCATGGCC AGTTCTATGA CCTCCTCAAC ATATTCGAGC TCAACGGTTT ACCCTCGGAG 
ACCAACCCCT ATATATTTAA TGGTGACTTT GTGGACCGAG GCTCCTTCTC TGTAGAAGTG 
ATCCTCACCC TTTTCGGCTT CAAGCTCCTG TACCCAGATC ACTTTCACCT CCTTCGAGGC 
AACCACGAGA CAGACAACAT GAACCAGATC TACGGTTTCG AGGGTGAGGT GAAGGCCAAG 
TACACAGCCC AGATGTACGA GCTCTTTAGC GAGGTGTTCG AGTGGCTCCC GTTGGCCCAG 
TGCATCAACG GCAAAGTGCT GATCATGCAC GGAGGCCTGT TCAGTGAAGA CGGTGTCACC 
CTGGATGACA TCCGGAAAAT TGAGCGGAAT CGACAACCCC CAGATTCAGG GCCCATGTGT 
GACCTGCTCT GGTCAGATCC ACAGCCACAG AACGGGCGCT CGATCAGCAA GCGGGGCGTG 
AGCTGTCAGT TTGGGCCTGA CGTCACCAAG GCCTTCTTGG AAGAGAACAA CCTGGACTAT 
ATCATCCGCA GCCACGAAGT CAAGGCCGAG GGCTACGAGG TGGCTCACGG AGGCCGCTGT 
GTCACCGTCT TCTCTGCCCC CAACTACTGC GACCAGATGG GGAACAAAGC CTCCTACATC 
CACCTCCAGG GCTCTGACCT ACGGCCTCAG TTCCACCAGT TCACAGCAGT GCCTCATCCC 
AACGTCAAGC CCATGGCCTA TGCCAACACG CTGCTGCAGC TAGGAATGAT GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PPP5C ( NM_001204284.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001191213.1 Homo sapiens protein phosphatase 5 catalytic subunit (PPP5C), transcript variant 2, mRNA.

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CloneID	OHu15715
Clone ID Related Accession (Same CDS sequence)	NM_001204284.2 , NM_001204284.1
Accession Version	NM_001204284.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1434bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-22
Organism	Homo sapiens(human)
Product	serine/threonine-protein phosphatase 5 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA545760.1 and AC007193.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting protein (isoform 2) is shorter compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.215143.1, SRR3476690.101336.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGATGG CGGAGGGCGA GAGGACTGAG TGTGCTGAGC CCCCCCGGGA CGAACCCCCG 
GCTGATGGAG CTCTGAAGCG GGCAGAGGAG CTCAAGACTC AGGCCAATGA CTACTTCAAA 
GCCAAGGACT ACGAGAACGC CATCAAGTTC TACAGCCAGG CCATCGAGCT GAACCCCAGC 
AATGCCATCT ACTATGGCAA CCGCAGCCTG GCCTACCTGC GCACTGAGTG CTATGGCTAC 
GCGCTGGGAG ACGCCACGCG GGCCATTGAG CTGGACAAGA AGTACATCAA GGGTTATTAC 
CGCCGGGCTG CCAGCAACAT GGCACTGGGC AAGTTCCGGG CCGCGCTGCG AGACTACGAG 
ACGGTGGTCA AGGTGAAGCC CCATGACAAG GATGCCAAAA TGAAATACCA GGAGTGCAAC 
AAGATCGTGA AGCAGAAGGC CTTTGAGCGG GCCATCGCGG GCGACGAGCA CAAGCGCTCC 
GTGGTGGACT CGCTGGACAT CGAGAGCATG ACCATTGAGG ATGAGTACAG CGGACCCAAG 
CTTGAAGACG GCAAAGTGAC AATCAGTTTC ATGAAGGAGC TCATGCAGTG GTACAAGGAC 
CAGAAGAAAC TGCACCGGAA ATGTGCCTAC CAGACAGAGA AGATTACAGT ATGTGGGGAC 
ACCCATGGCC AGTTCTATGA CCTCCTCAAC ATATTCGAGC TCAACGGTTT ACCCTCGGAG 
ACCAACCCCT ATATATTTAA TGGTGACTTT GTGGACCGAG GCTCCTTCTC TGTAGAAGTG 
ATCCTCACCC TTTTCGGCTT CAAGCTCCTG TACCCAGATC ACTTTCACCT CCTTCGAGGC 
AACCACGAGA CAGACAACAT GAACCAGATC TACGGTTTCG AGGGTGAGGT GAAGGCCAAG 
TACACAGCCC AGATGTACGA GCTCTTTAGC GAGGTGTTCG AGTGGCTCCC GTTGGCCCAG 
TGCATCAACG GCAAAGTGCT GATCATGCAC GGAGGCCTGT TCAGTGAAGA CGGTGTCACC 
CTGGATGACA TCCGGAAAAT TGAGCGGAAT CGACAACCCC CAGATTCAGG GCCCATGTGT 
GACCTGCTCT GGTCAGATCC ACAGCCACAG AACGGGCGCT CGATCAGCAA GCGGGGCGTG 
AGCTGTCAGT TTGGGCCTGA CGTCACCAAG GCCTTCTTGG AAGAGAACAA CCTGGACTAT 
ATCATCCGCA GCCACGAAGT CAAGGCCGAG GGCTACGAGG TGGCTCACGG AGGCCGCTGT 
GTCACCGTCT TCTCTGCCCC CAACTACTGC GACCAGATGG GGAACAAAGC CTCCTACATC 
CACCTCCAGG GCTCTGACCT ACGGCCTCAG TTCCACCAGT TCACAGCAGT GCCTCATCCC 
AACGTCAAGC CCATGGCCTA TGCCAACACG CTGCTGCAGC TAGGAATGAT GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001191213.1
CDS	104..1537
Translation	MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQTEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQLGMM

Target ORF information:

RefSeq Version	NM_001204284.1
Organism	Homo sapiens(human)
Definition	Homo sapiens protein phosphatase 5 catalytic subunit (PPP5C), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001204284.1

ORF Insert Sequence:

ATGGCGATGG CGGAGGGCGA GAGGACTGAG TGTGCTGAGC CCCCCCGGGA CGAACCCCCG 
GCTGATGGAG CTCTGAAGCG GGCAGAGGAG CTCAAGACTC AGGCCAATGA CTACTTCAAA 
GCCAAGGACT ACGAGAACGC CATCAAGTTC TACAGCCAGG CCATCGAGCT GAACCCCAGC 
AATGCCATCT ACTATGGCAA CCGCAGCCTG GCCTACCTGC GCACTGAGTG CTATGGCTAC 
GCGCTGGGAG ACGCCACGCG GGCCATTGAG CTGGACAAGA AGTACATCAA GGGTTATTAC 
CGCCGGGCTG CCAGCAACAT GGCACTGGGC AAGTTCCGGG CCGCGCTGCG AGACTACGAG 
ACGGTGGTCA AGGTGAAGCC CCATGACAAG GATGCCAAAA TGAAATACCA GGAGTGCAAC 
AAGATCGTGA AGCAGAAGGC CTTTGAGCGG GCCATCGCGG GCGACGAGCA CAAGCGCTCC 
GTGGTGGACT CGCTGGACAT CGAGAGCATG ACCATTGAGG ATGAGTACAG CGGACCCAAG 
CTTGAAGACG GCAAAGTGAC AATCAGTTTC ATGAAGGAGC TCATGCAGTG GTACAAGGAC 
CAGAAGAAAC TGCACCGGAA ATGTGCCTAC CAGACAGAGA AGATTACAGT ATGTGGGGAC 
ACCCATGGCC AGTTCTATGA CCTCCTCAAC ATATTCGAGC TCAACGGTTT ACCCTCGGAG 
ACCAACCCCT ATATATTTAA TGGTGACTTT GTGGACCGAG GCTCCTTCTC TGTAGAAGTG 
ATCCTCACCC TTTTCGGCTT CAAGCTCCTG TACCCAGATC ACTTTCACCT CCTTCGAGGC 
AACCACGAGA CAGACAACAT GAACCAGATC TACGGTTTCG AGGGTGAGGT GAAGGCCAAG 
TACACAGCCC AGATGTACGA GCTCTTTAGC GAGGTGTTCG AGTGGCTCCC GTTGGCCCAG 
TGCATCAACG GCAAAGTGCT GATCATGCAC GGAGGCCTGT TCAGTGAAGA CGGTGTCACC 
CTGGATGACA TCCGGAAAAT TGAGCGGAAT CGACAACCCC CAGATTCAGG GCCCATGTGT 
GACCTGCTCT GGTCAGATCC ACAGCCACAG AACGGGCGCT CGATCAGCAA GCGGGGCGTG 
AGCTGTCAGT TTGGGCCTGA CGTCACCAAG GCCTTCTTGG AAGAGAACAA CCTGGACTAT 
ATCATCCGCA GCCACGAAGT CAAGGCCGAG GGCTACGAGG TGGCTCACGG AGGCCGCTGT 
GTCACCGTCT TCTCTGCCCC CAACTACTGC GACCAGATGG GGAACAAAGC CTCCTACATC 
CACCTCCAGG GCTCTGACCT ACGGCCTCAG TTCCACCAGT TCACAGCAGT GCCTCATCCC 
AACGTCAAGC CCATGGCCTA TGCCAACACG CTGCTGCAGC TAGGAATGAT GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PPP5C ( XM_017026935.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016882424.1 Homo sapiens protein phosphatase 5 catalytic subunit (PPP5C), transcript variant X1, mRNA.

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CloneID	OHu88546
Clone ID Related Accession (Same CDS sequence)	XM_017026935.1 , XM_017026935.2
Accession Version	XM_017026935.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1656bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	serine/threonine-protein phosphatase 5 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGATGG CGGAGGGCGA GAGGACTGAG TGTGCTGAGC CCCCCCGGGA CGAACCCCCG 
GCTGATGGAG CTCTGAAGCG GGCAGAGGAG CTCAAGACTC AGGCCAATGA CTACTTCAAA 
GCCAAGGACT ACGAGAACGC CATCAAGTTC TACAGCCAGG CCATCGAGCT GAACCCCAGC 
AATGCCATCT ACTATGGCAA CCGCAGCCTG GCCTACCTGC GCACTGAGTG CTATGGCTAC 
GCGCTGGGAG ACGCCACGCG GGCCATTGAG CTGGACAAGA AGTACATCAA GGGTTATTAC 
CGCCGGGCTG CCAGCAACAT GGCACTGGGC AAGTTCCGGG CCGCGCTGCG AGACTACGAG 
ACGGTGGTCA AGGTGAAGCC CCATGACAAG GATGCCAAAA TGAAATACCA GGAGTGCAAC 
AAGATCGTGA AGCAGAAGGC CTTTGAGCGG GCCATCGCGG GCGACGAGCA CAAGCGCTCC 
GTGGTGGACT CGCTGGACAT CGAGAGCATG ACCATTGAGG ATGAGTACAG CGGACCCAAG 
CTTGAAGACG GCAAAGTGAC AATCAGTTTC ATGAAGGAGC TCATGCAGTG GTACAAGGAC 
CAGAAGAAAC TGCACCGGAA ATGTGCCTAC CAGATTCTGG TACAGGTCAA AGAGGTCCTC 
TCCAAGCTGA GCACGCTCGT GGAAACCACA CTCAAAGAGA CAGAGAAGAT TACAGTATGT 
GGGGACACCC ATGGCCAGTT CTATGACCTC CTCAACATAT TCGAGCTCAA CGGTTTACCC 
TCGGAGACCA ACCCCTATAT ATTTAATGGT GACTTTGTGG ACCGAGGCTC CTTCTCTGTA 
GAAGTGATCC TCACCCTTTT CGGCTTCAAG CTCCTGTACC CAGATCACTT TCACCTCCTT 
CGAGGCAACC ACGAGACAGA CAACATGAAC CAGATCTACG GTTTCGAGGG TGAGGTGAAG 
GCCAAGTACA CAGCCCAGAT GTACGAGCTC TTTAGCGAGG TGTTCGAGTG GCTCCCGTTG 
GCCCAGTGCA TCAACGGCAA AGTGCTGATC ATGCACGGAG GCCTGTTCAG TGAAGACGGT 
GTCACCCTGG ATGACATCCG GAAAATTGAG CGGAATCGAC AACCCCCAGA TTCAGGGCCC 
ATGTGTGACC TGCTCTGGTC AGATCCACAG CCACAGAACG GGCGCTCGAT CAGCAAGCGG 
GGCGTGAGCT GTCAGTTTGG GCCTGACGTC ACCAAGGCCT TCTTGGAAGA GAACAACCTG 
GACTATATCA TCCGCAGCCA CGAAGTCAAG GCCGAGGGCT ACGAGGTGGC TCACGGAGGC 
CGCTGTGTCA CCGTCTTCTC TGCCCCCAAC TACTGCGACC AGATGGGGAA CAAAGCCTCC 
TACATCCACC TCCAGGGCTC TGACCTACGG CCTCAGTTCC ACCAGTTCAC AGCAGTGGTG 
AGTCACCCCT CAGGGCCCCT GCCCCTTCCA TCCCGGCCTG GGGACAAGGA GGCTGAGACC 
CTGGTAAGGG GCAGGGGTAG GTTCTGCCGG TGGGTGCTCA GGGGCTCTGT TCTGACTTCT 
GTCCATCCCA CCTGCCCTGG TCCCACAGCC TCATCCCAAC GTCAAGCCCA TGGCCTATGC 
CAACACGCTG CTGCAGCTAG GAATGATGTG AGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016882424.1
CDS	99..1754
Translation	MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVVSHPSGPLPLPSRPGDKEAETLVRGRGRFCRWVLRGSVLTSVHPTCPGPTASSQRQAHGLCQHAAAARNDVR

Target ORF information:

RefSeq Version	XM_017026935.1
Organism	Homo sapiens(human)
Definition	Homo sapiens protein phosphatase 5 catalytic subunit (PPP5C), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017026935.1

ORF Insert Sequence:

ATGGCGATGG CGGAGGGCGA GAGGACTGAG TGTGCTGAGC CCCCCCGGGA CGAACCCCCG 
GCTGATGGAG CTCTGAAGCG GGCAGAGGAG CTCAAGACTC AGGCCAATGA CTACTTCAAA 
GCCAAGGACT ACGAGAACGC CATCAAGTTC TACAGCCAGG CCATCGAGCT GAACCCCAGC 
AATGCCATCT ACTATGGCAA CCGCAGCCTG GCCTACCTGC GCACTGAGTG CTATGGCTAC 
GCGCTGGGAG ACGCCACGCG GGCCATTGAG CTGGACAAGA AGTACATCAA GGGTTATTAC 
CGCCGGGCTG CCAGCAACAT GGCACTGGGC AAGTTCCGGG CCGCGCTGCG AGACTACGAG 
ACGGTGGTCA AGGTGAAGCC CCATGACAAG GATGCCAAAA TGAAATACCA GGAGTGCAAC 
AAGATCGTGA AGCAGAAGGC CTTTGAGCGG GCCATCGCGG GCGACGAGCA CAAGCGCTCC 
GTGGTGGACT CGCTGGACAT CGAGAGCATG ACCATTGAGG ATGAGTACAG CGGACCCAAG 
CTTGAAGACG GCAAAGTGAC AATCAGTTTC ATGAAGGAGC TCATGCAGTG GTACAAGGAC 
CAGAAGAAAC TGCACCGGAA ATGTGCCTAC CAGATTCTGG TACAGGTCAA AGAGGTCCTC 
TCCAAGCTGA GCACGCTCGT GGAAACCACA CTCAAAGAGA CAGAGAAGAT TACAGTATGT 
GGGGACACCC ATGGCCAGTT CTATGACCTC CTCAACATAT TCGAGCTCAA CGGTTTACCC 
TCGGAGACCA ACCCCTATAT ATTTAATGGT GACTTTGTGG ACCGAGGCTC CTTCTCTGTA 
GAAGTGATCC TCACCCTTTT CGGCTTCAAG CTCCTGTACC CAGATCACTT TCACCTCCTT 
CGAGGCAACC ACGAGACAGA CAACATGAAC CAGATCTACG GTTTCGAGGG TGAGGTGAAG 
GCCAAGTACA CAGCCCAGAT GTACGAGCTC TTTAGCGAGG TGTTCGAGTG GCTCCCGTTG 
GCCCAGTGCA TCAACGGCAA AGTGCTGATC ATGCACGGAG GCCTGTTCAG TGAAGACGGT 
GTCACCCTGG ATGACATCCG GAAAATTGAG CGGAATCGAC AACCCCCAGA TTCAGGGCCC 
ATGTGTGACC TGCTCTGGTC AGATCCACAG CCACAGAACG GGCGCTCGAT CAGCAAGCGG 
GGCGTGAGCT GTCAGTTTGG GCCTGACGTC ACCAAGGCCT TCTTGGAAGA GAACAACCTG 
GACTATATCA TCCGCAGCCA CGAAGTCAAG GCCGAGGGCT ACGAGGTGGC TCACGGAGGC 
CGCTGTGTCA CCGTCTTCTC TGCCCCCAAC TACTGCGACC AGATGGGGAA CAAAGCCTCC 
TACATCCACC TCCAGGGCTC TGACCTACGG CCTCAGTTCC ACCAGTTCAC AGCAGTGGTG 
AGTCACCCCT CAGGGCCCCT GCCCCTTCCA TCCCGGCCTG GGGACAAGGA GGCTGAGACC 
CTGGTAAGGG GCAGGGGTAG GTTCTGCCGG TGGGTGCTCA GGGGCTCTGT TCTGACTTCT 
GTCCATCCCA CCTGCCCTGG TCCCACAGCC TCATCCCAAC GTCAAGCCCA TGGCCTATGC 
CAACACGCTG CTGCAGCTAG GAATGATGTG AGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PPP5C ( XM_017026935.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_016882424.1 Homo sapiens protein phosphatase 5 catalytic subunit (PPP5C), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu88546
Clone ID Related Accession (Same CDS sequence)	XM_017026935.1 , XM_017026935.2
Accession Version	XM_017026935.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1656bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	serine/threonine-protein phosphatase 5 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017026935.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGATGG CGGAGGGCGA GAGGACTGAG TGTGCTGAGC CCCCCCGGGA CGAACCCCCG 
GCTGATGGAG CTCTGAAGCG GGCAGAGGAG CTCAAGACTC AGGCCAATGA CTACTTCAAA 
GCCAAGGACT ACGAGAACGC CATCAAGTTC TACAGCCAGG CCATCGAGCT GAACCCCAGC 
AATGCCATCT ACTATGGCAA CCGCAGCCTG GCCTACCTGC GCACTGAGTG CTATGGCTAC 
GCGCTGGGAG ACGCCACGCG GGCCATTGAG CTGGACAAGA AGTACATCAA GGGTTATTAC 
CGCCGGGCTG CCAGCAACAT GGCACTGGGC AAGTTCCGGG CCGCGCTGCG AGACTACGAG 
ACGGTGGTCA AGGTGAAGCC CCATGACAAG GATGCCAAAA TGAAATACCA GGAGTGCAAC 
AAGATCGTGA AGCAGAAGGC CTTTGAGCGG GCCATCGCGG GCGACGAGCA CAAGCGCTCC 
GTGGTGGACT CGCTGGACAT CGAGAGCATG ACCATTGAGG ATGAGTACAG CGGACCCAAG 
CTTGAAGACG GCAAAGTGAC AATCAGTTTC ATGAAGGAGC TCATGCAGTG GTACAAGGAC 
CAGAAGAAAC TGCACCGGAA ATGTGCCTAC CAGATTCTGG TACAGGTCAA AGAGGTCCTC 
TCCAAGCTGA GCACGCTCGT GGAAACCACA CTCAAAGAGA CAGAGAAGAT TACAGTATGT 
GGGGACACCC ATGGCCAGTT CTATGACCTC CTCAACATAT TCGAGCTCAA CGGTTTACCC 
TCGGAGACCA ACCCCTATAT ATTTAATGGT GACTTTGTGG ACCGAGGCTC CTTCTCTGTA 
GAAGTGATCC TCACCCTTTT CGGCTTCAAG CTCCTGTACC CAGATCACTT TCACCTCCTT 
CGAGGCAACC ACGAGACAGA CAACATGAAC CAGATCTACG GTTTCGAGGG TGAGGTGAAG 
GCCAAGTACA CAGCCCAGAT GTACGAGCTC TTTAGCGAGG TGTTCGAGTG GCTCCCGTTG 
GCCCAGTGCA TCAACGGCAA AGTGCTGATC ATGCACGGAG GCCTGTTCAG TGAAGACGGT 
GTCACCCTGG ATGACATCCG GAAAATTGAG CGGAATCGAC AACCCCCAGA TTCAGGGCCC 
ATGTGTGACC TGCTCTGGTC AGATCCACAG CCACAGAACG GGCGCTCGAT CAGCAAGCGG 
GGCGTGAGCT GTCAGTTTGG GCCTGACGTC ACCAAGGCCT TCTTGGAAGA GAACAACCTG 
GACTATATCA TCCGCAGCCA CGAAGTCAAG GCCGAGGGCT ACGAGGTGGC TCACGGAGGC 
CGCTGTGTCA CCGTCTTCTC TGCCCCCAAC TACTGCGACC AGATGGGGAA CAAAGCCTCC 
TACATCCACC TCCAGGGCTC TGACCTACGG CCTCAGTTCC ACCAGTTCAC AGCAGTGGTG 
AGTCACCCCT CAGGGCCCCT GCCCCTTCCA TCCCGGCCTG GGGACAAGGA GGCTGAGACC 
CTGGTAAGGG GCAGGGGTAG GTTCTGCCGG TGGGTGCTCA GGGGCTCTGT TCTGACTTCT 
GTCCATCCCA CCTGCCCTGG TCCCACAGCC TCATCCCAAC GTCAAGCCCA TGGCCTATGC 
CAACACGCTG CTGCAGCTAG GAATGATGTG AGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016882424.1
CDS	29..1684
Translation	MAMAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVVSHPSGPLPLPSRPGDKEAETLVRGRGRFCRWVLRGSVLTSVHPTCPGPTASSQRQAHGLCQHAAAARNDVR

Target ORF information:

RefSeq Version	XM_017026935.2
Organism	Homo sapiens(human)
Definition	Homo sapiens protein phosphatase 5 catalytic subunit (PPP5C), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017026935.2

ORF Insert Sequence:

ATGGCGATGG CGGAGGGCGA GAGGACTGAG TGTGCTGAGC CCCCCCGGGA CGAACCCCCG 
GCTGATGGAG CTCTGAAGCG GGCAGAGGAG CTCAAGACTC AGGCCAATGA CTACTTCAAA 
GCCAAGGACT ACGAGAACGC CATCAAGTTC TACAGCCAGG CCATCGAGCT GAACCCCAGC 
AATGCCATCT ACTATGGCAA CCGCAGCCTG GCCTACCTGC GCACTGAGTG CTATGGCTAC 
GCGCTGGGAG ACGCCACGCG GGCCATTGAG CTGGACAAGA AGTACATCAA GGGTTATTAC 
CGCCGGGCTG CCAGCAACAT GGCACTGGGC AAGTTCCGGG CCGCGCTGCG AGACTACGAG 
ACGGTGGTCA AGGTGAAGCC CCATGACAAG GATGCCAAAA TGAAATACCA GGAGTGCAAC 
AAGATCGTGA AGCAGAAGGC CTTTGAGCGG GCCATCGCGG GCGACGAGCA CAAGCGCTCC 
GTGGTGGACT CGCTGGACAT CGAGAGCATG ACCATTGAGG ATGAGTACAG CGGACCCAAG 
CTTGAAGACG GCAAAGTGAC AATCAGTTTC ATGAAGGAGC TCATGCAGTG GTACAAGGAC 
CAGAAGAAAC TGCACCGGAA ATGTGCCTAC CAGATTCTGG TACAGGTCAA AGAGGTCCTC 
TCCAAGCTGA GCACGCTCGT GGAAACCACA CTCAAAGAGA CAGAGAAGAT TACAGTATGT 
GGGGACACCC ATGGCCAGTT CTATGACCTC CTCAACATAT TCGAGCTCAA CGGTTTACCC 
TCGGAGACCA ACCCCTATAT ATTTAATGGT GACTTTGTGG ACCGAGGCTC CTTCTCTGTA 
GAAGTGATCC TCACCCTTTT CGGCTTCAAG CTCCTGTACC CAGATCACTT TCACCTCCTT 
CGAGGCAACC ACGAGACAGA CAACATGAAC CAGATCTACG GTTTCGAGGG TGAGGTGAAG 
GCCAAGTACA CAGCCCAGAT GTACGAGCTC TTTAGCGAGG TGTTCGAGTG GCTCCCGTTG 
GCCCAGTGCA TCAACGGCAA AGTGCTGATC ATGCACGGAG GCCTGTTCAG TGAAGACGGT 
GTCACCCTGG ATGACATCCG GAAAATTGAG CGGAATCGAC AACCCCCAGA TTCAGGGCCC 
ATGTGTGACC TGCTCTGGTC AGATCCACAG CCACAGAACG GGCGCTCGAT CAGCAAGCGG 
GGCGTGAGCT GTCAGTTTGG GCCTGACGTC ACCAAGGCCT TCTTGGAAGA GAACAACCTG 
GACTATATCA TCCGCAGCCA CGAAGTCAAG GCCGAGGGCT ACGAGGTGGC TCACGGAGGC 
CGCTGTGTCA CCGTCTTCTC TGCCCCCAAC TACTGCGACC AGATGGGGAA CAAAGCCTCC 
TACATCCACC TCCAGGGCTC TGACCTACGG CCTCAGTTCC ACCAGTTCAC AGCAGTGGTG 
AGTCACCCCT CAGGGCCCCT GCCCCTTCCA TCCCGGCCTG GGGACAAGGA GGCTGAGACC 
CTGGTAAGGG GCAGGGGTAG GTTCTGCCGG TGGGTGCTCA GGGGCTCTGT TCTGACTTCT 
GTCCATCCCA CCTGCCCTGG TCCCACAGCC TCATCCCAAC GTCAAGCCCA TGGCCTATGC 
CAACACGCTG CTGCAGCTAG GAATGATGTG AGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Protein phosphatase 5 regulates titin phosphorylation and function at a sarcomere-associated mechanosensor complex in cardiomyocytes.
Nature communications9(1)262(2018 Jan)
Krysiak J,Unger A,Beckendorf L,Hamdani N,von Frieling-Salewsky M,Redfield MM,Dos Remedios CG,Sheikh F,Gergs U,Boknik P,Linke WA

Tumor suppressor Tsc1 is a new Hsp90 co-chaperone that facilitates folding of kinase and non-kinase clients.
The EMBO journal36(24)3650-3665(2017 12)
Woodford MR,Sager RA,Marris E,Dunn DM,Blanden AR,Murphy RL,Rensing N,Shapiro O,Panaretou B,Prodromou C,Loh SN,Gutmann DH,Bourboulia D,Bratslavsky G,Wong M,Mollapour M

Disruption of serine/threonine protein phosphatase 5 inhibits tumorigenesis of urinary bladder cancer cells.
International journal of oncology51(1)39-48(2017 Jul)
Chen M,Lv JM,Ye JQ,Cui XG,Qu FJ,Chen L,Liu X,Pan XW,Li L,Huang H,Yang QW,Chen J,Wang LH,Gao Y,Xu DF

Roles of tau protein in health and disease.
Acta neuropathologica133(5)665-704(2017 May)
Guo T,Noble W,Hanger DP

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PPP5C cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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