LARP6 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	LARP6
Entrez Gene ID	55323
Full Name	La ribonucleoprotein domain family member 6
Synonyms	ACHN
General protein information	Preferred Names La ribonucleoprotein domain family member 6 Names la-related protein 6 acheron death-associated LA motif protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 15 Map Location: 15q23
Disorder MIM:	611300

mRNA and Protein(s)

mRNA	Protein	Name
NM_197958.2	NP_932062.1	la-related protein 6 isoform 2
NM_001286679.1	NP_001273608.1	la-related protein 6 isoform 3
NM_197958.3	NP_932062.1	la-related protein 6 isoform 2
NM_018357.3	NP_060827.2	la-related protein 6 isoform 1
NM_001286679.2	NP_001273608.1	la-related protein 6 isoform 3
NM_018357.4	NP_060827.2	la-related protein 6 isoform 1

Pathways from BioSystems

Homologies

Homo sapiens (human)	LARP6	NP_060827.2
Pan troglodytes (chimpanzee)	LARP6	NP_001233506.1
Gallus gallus (chicken)	LARP6	XP_413777.3
Danio rerio (zebrafish)	larp6	NP_956197.1
Bos taurus (cattle)	LARP6	NP_001092675.1
Rattus norvegicus (Norway rat)	Larp6	NP_001101624.1
	LARP6	XP_001088126.1
Mus musculus (house mouse)	Larp6	NP_080511.2
Canis lupus familiaris (dog)	LARP6	XP_005638605.1
Xenopus tropicalis (tropical clawed frog)	larp6	NP_001008144.1

Gene Ontology
Bibliography

Related articles in PubMed

The La and related RNA-binding proteins (LARPs): structures, functions, and evolving perspectives.
Maraia RJ, Mattijssen S, Cruz-Gallardo I, Conte MR
Wiley interdisciplinary reviews. RNA8(6)(2017 Nov)

mTORC1 phosphorylates LARP6 to stimulate type I collagen expression.
Zhang Y, Stefanovic B
Scientific reports741173(2017 Jan)

Akt mediated phosphorylation of LARP6; critical step in biosynthesis of type I collagen.
Zhang Y, Stefanovic B
Scientific reports622597(2016 Mar)

Synergic interplay of the La motif, RRM1 and the interdomain linker of LARP6 in the recognition of collagen mRNA expands the RNA binding repertoire of the La module.
Martino L, Pennell S, Kelly G, Busi B, Brown P, Atkinson RA, Salisbury NJ, Ooi ZH, See KW, Smerdon SJ, Alfano C, Bui TT, Conte MR
Nucleic acids research43(1)645-60(2015 Jan)

Characterization of binding of LARP6 to the 5' stem-loop of collagen mRNAs: implications for synthesis of type I collagen.
Stefanovic L, Longo L, Zhang Y, Stefanovic B
RNA biology11(11)1386-401(2014)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Akt mediated phosphorylation of LARP6; critical step in biosynthesis of type I collagen
Title: Akt mediated phosphorylation of LARP6; critical step in biosynthesis of type I collagen.

The study presents the structure of the La motif and RRM1 of human LARP6 uncovering in both cases considerable structural variation in comparison to the equivalent domains in La and revealing an unprecedented fold for the RRM1.
Title: Synergic interplay of the La motif, RRM1 and the interdomain linker of LARP6 in the recognition of collagen mRNA expands the RNA binding repertoire of the La module.

LARP6 is a critical mediator by which IGF-1 augments synthesis of collagen type I in vascular smooth muscle
Title: Insulin-like growth factor-1 increases synthesis of collagen type I via induction of the mRNA-binding protein LARP6 expression and binding to the 5' stem-loop of COL1a1 and COL1a2 mRNA.

We postulate that collagen mRNAs directly partition to the endoplasmic reticulum membrane prior to synthesis of the signal peptide and that LARP6 and nonmuscle myosin filaments mediate this process.
Title: Role of LARP6 and nonmuscle myosin in partitioning of collagen mRNAs to the ER membrane.

Data indicate that LA motif protein LARP6 binding to spliced leader RNA (5'SL) of collagen alpha2(I) mRNA is more stable than the binding to 5'SL of alpha1(I) mRNA.
Title: Characterization of binding of LARP6 to the 5' stem-loop of collagen mRNAs: implications for synthesis of type I collagen.

The following LARP6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LARP6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu01150	NM_018357.4 Latest version!	Homo sapiens La ribonucleoprotein 6, translational regulator (LARP6), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu27637	NM_001286679.2 Latest version!	Homo sapiens La ribonucleoprotein 6, translational regulator (LARP6), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu02438	NM_197958.3 Latest version!	Homo sapiens La ribonucleoprotein 6, translational regulator (LARP6), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
View Old Accession Versions >>
OHu02438	NM_197958.2	Homo sapiens La ribonucleoprotein domain family member 6 (LARP6), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu27637	NM_001286679.1	Homo sapiens La ribonucleoprotein domain family member 6 (LARP6), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu01150	NM_018357.3	Homo sapiens La ribonucleoprotein domain family member 6 (LARP6), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

LARP6 ( NM_018357.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_060827.2 Homo sapiens La ribonucleoprotein domain family member 6 (LARP6), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu01150
Clone ID Related Accession (Same CDS sequence)	NM_018357.3 , NM_018357.4
Accession Version	NM_018357.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1476bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Homo sapiens(human)
Product	la-related protein 6 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DN992782.1, AL833876.1 and AI376944.1. On Nov 14, 2013 this sequence version replaced NM_018357.2. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.156424.1, SRR1803611.160478.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2152568, SAMEA2155974 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCCAGT CCGGCGGGGA GGCTCGGCCC GGGCCCAAGA CGGCGGTGCA GATCCGCGTC 
GCCATCCAGG AGGCCGAGGA CGTGGACGAG TTGGAGGACG AGGAGGAGGG GGCGGAGACT 
CGGGGCGCCG GGGACCCGGC CCGGTACCTC AGCCCCGGCT GGGGCAGCGC GAGCGAGGAG 
GAGCCGAGCC GCGGGCACAG TGGCACCACT GCAAGTGGAG GTGAGAACGA GCGTGAGGAC 
CTGGAGCAGG AGTGGAAGCC CCCGGATGAG GAGTTGATCA AGAAACTGGT GGATCAGATC 
GAATTCTACT TTTCTGATGA AAACCTGGAG AAGGACGCCT TTTTGCTAAA ACACGTGAGG 
AGGAACAAGC TGGGATATGT GAGCGTTAAG CTACTCACAT CCTTCAAAAA GGTGAAACAT 
CTTACACGGG ACTGGAGAAC CACAGCACAT GCTTTGAAGT ATTCAGTGGT CCTTGAGTTG 
AATGAGGACC ACCGGAAGGT GAGGAGGACC ACCCCCGTCC CACTGTTCCC CAACGAGAAC 
CTCCCCAGCA AGATGCTCCT GGTCTATGAT CTCTACTTGT CTCCTAAGCT GTGGGCTCTG 
GCCACCCCCC AGAAGAATGG AAGGGTGCAA GAGAAGGTGA TGGAACACCT GCTCAAGCTT 
TTTGGGACTT TTGGAGTCAT CTCATCAGTG CGGATCCTCA AACCTGGGAG AGAGCTGCCC 
CCTGACATCC GGAGGATCAG CAGCCGCTAC AGCCAAGTGG GGACCCAGGA GTGCGCCATC 
GTGGAGTTCG AGGAGGTGGA AGCAGCCATC AAAGCCCATG AGTTCATGAT CACAGAATCT 
CAGGGCAAAG AGAACATGAA AGCTGTCCTG ATTGGTATGA AGCCACCCAA AAAGAAACCT 
GCCAAAGACA AAAATCATGA CGAGGAGCCC ACTGCGAGCA TCCACCTGAA CAAGTCCCTG 
AACAAGAGAG TCGAGGAGCT TCAGTACATG GGTGATGAGT CTTCTGCCAA CAGCTCCTCT 
GACCCCGAGA GCAACCCCAC ATCCCCTATG GCGGGCCGAC GGCACGCGGC CACCAACAAG 
CTCAGCCCGT CTGGCCACCA GAATCTCTTT CTGAGTCCAA ATGCCTCCCC GTGCACAAGT 
CCTTGGAGCA GCCCCTTGGC CCAACGCAAA GGCGTTTCCA GAAAGTCCCC ACTGGCGGAG 
GAAGGTAGAC TGAACTGCAG CACCAGCCCT GAGATCTTCC GCAAGTGTAT GGATTATTCC 
TCTGACAGCA GCGTCACTCC CTCTGGCAGC CCCTGGGTCC GGAGGCGTCG CCAAGCCGAG 
ATGGGGACCC AGGAGAAAAG CCCCGGTACG AGTCCCCTGC TCTCCCGGAA GATGCAGACT 
GCAGATGGGC TACCCGTAGG GGTGCTGAGG TTGCCCAGGG GTCCTGACAA CACCAGAGGA 
TTTCATGGCC ATGAGAGGAG CAGGGCCTGT GTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060827.2
CDS	178..1653
Translation	MAQSGGEARPGPKTAVQIRVAIQEAEDVDELEDEEEGAETRGAGDPARYLSPGWGSASEEEPSRGHSGTTASGGENEREDLEQEWKPPDEELIKKLVDQIEFYFSDENLEKDAFLLKHVRRNKLGYVSVKLLTSFKKVKHLTRDWRTTAHALKYSVVLELNEDHRKVRRTTPVPLFPNENLPSKMLLVYDLYLSPKLWALATPQKNGRVQEKVMEHLLKLFGTFGVISSVRILKPGRELPPDIRRISSRYSQVGTQECAIVEFEEVEAAIKAHEFMITESQGKENMKAVLIGMKPPKKKPAKDKNHDEEPTASIHLNKSLNKRVEELQYMGDESSANSSSDPESNPTSPMAGRRHAATNKLSPSGHQNLFLSPNASPCTSPWSSPLAQRKGVSRKSPLAEEGRLNCSTSPEIFRKCMDYSSDSSVTPSGSPWVRRRRQAEMGTQEKSPGTSPLLSRKMQTADGLPVGVLRLPRGPDNTRGFHGHERSRACV

Target ORF information:

RefSeq Version	NM_018357.3
Organism	Homo sapiens(human)
Definition	Homo sapiens La ribonucleoprotein domain family member 6 (LARP6), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018357.3

ORF Insert Sequence:

ATGGCCCAGT CCGGCGGGGA GGCTCGGCCC GGGCCCAAGA CGGCGGTGCA GATCCGCGTC 
GCCATCCAGG AGGCCGAGGA CGTGGACGAG TTGGAGGACG AGGAGGAGGG GGCGGAGACT 
CGGGGCGCCG GGGACCCGGC CCGGTACCTC AGCCCCGGCT GGGGCAGCGC GAGCGAGGAG 
GAGCCGAGCC GCGGGCACAG TGGCACCACT GCAAGTGGAG GTGAGAACGA GCGTGAGGAC 
CTGGAGCAGG AGTGGAAGCC CCCGGATGAG GAGTTGATCA AGAAACTGGT GGATCAGATC 
GAATTCTACT TTTCTGATGA AAACCTGGAG AAGGACGCCT TTTTGCTAAA ACACGTGAGG 
AGGAACAAGC TGGGATATGT GAGCGTTAAG CTACTCACAT CCTTCAAAAA GGTGAAACAT 
CTTACACGGG ACTGGAGAAC CACAGCACAT GCTTTGAAGT ATTCAGTGGT CCTTGAGTTG 
AATGAGGACC ACCGGAAGGT GAGGAGGACC ACCCCCGTCC CACTGTTCCC CAACGAGAAC 
CTCCCCAGCA AGATGCTCCT GGTCTATGAT CTCTACTTGT CTCCTAAGCT GTGGGCTCTG 
GCCACCCCCC AGAAGAATGG AAGGGTGCAA GAGAAGGTGA TGGAACACCT GCTCAAGCTT 
TTTGGGACTT TTGGAGTCAT CTCATCAGTG CGGATCCTCA AACCTGGGAG AGAGCTGCCC 
CCTGACATCC GGAGGATCAG CAGCCGCTAC AGCCAAGTGG GGACCCAGGA GTGCGCCATC 
GTGGAGTTCG AGGAGGTGGA AGCAGCCATC AAAGCCCATG AGTTCATGAT CACAGAATCT 
CAGGGCAAAG AGAACATGAA AGCTGTCCTG ATTGGTATGA AGCCACCCAA AAAGAAACCT 
GCCAAAGACA AAAATCATGA CGAGGAGCCC ACTGCGAGCA TCCACCTGAA CAAGTCCCTG 
AACAAGAGAG TCGAGGAGCT TCAGTACATG GGTGATGAGT CTTCTGCCAA CAGCTCCTCT 
GACCCCGAGA GCAACCCCAC ATCCCCTATG GCGGGCCGAC GGCACGCGGC CACCAACAAG 
CTCAGCCCGT CTGGCCACCA GAATCTCTTT CTGAGTCCAA ATGCCTCCCC GTGCACAAGT 
CCTTGGAGCA GCCCCTTGGC CCAACGCAAA GGCGTTTCCA GAAAGTCCCC ACTGGCGGAG 
GAAGGTAGAC TGAACTGCAG CACCAGCCCT GAGATCTTCC GCAAGTGTAT GGATTATTCC 
TCTGACAGCA GCGTCACTCC CTCTGGCAGC CCCTGGGTCC GGAGGCGTCG CCAAGCCGAG 
ATGGGGACCC AGGAGAAAAG CCCCGGTACG AGTCCCCTGC TCTCCCGGAA GATGCAGACT 
GCAGATGGGC TACCCGTAGG GGTGCTGAGG TTGCCCAGGG GTCCTGACAA CACCAGAGGA 
TTTCATGGCC ATGAGAGGAG CAGGGCCTGT GTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LARP6 ( NM_018357.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_060827.2 Homo sapiens La ribonucleoprotein 6, translational regulator (LARP6), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu01150
Clone ID Related Accession (Same CDS sequence)	NM_018357.3 , NM_018357.4
Accession Version	NM_018357.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1476bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-20
Organism	Homo sapiens(human)
Product	la-related protein 6 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DN992782.1, AL833876.1, AI376944.1 and AC009269.6. On May 17, 2019 this sequence version replaced NM_018357.3. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.108123.1, SRR1660805.195089.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2152568, SAMEA2155974 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000299213.10/ ENSP00000299213.7 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCCCAGT CCGGCGGGGA GGCTCGGCCC GGGCCCAAGA CGGCGGTGCA GATCCGCGTC 
GCCATCCAGG AGGCCGAGGA CGTGGACGAG TTGGAGGACG AGGAGGAGGG GGCGGAGACT 
CGGGGCGCCG GGGACCCGGC CCGGTACCTC AGCCCCGGCT GGGGCAGCGC GAGCGAGGAG 
GAGCCGAGCC GCGGGCACAG TGGCACCACT GCAAGTGGAG GTGAGAACGA GCGTGAGGAC 
CTGGAGCAGG AGTGGAAGCC CCCGGATGAG GAGTTGATCA AGAAACTGGT GGATCAGATC 
GAATTCTACT TTTCTGATGA AAACCTGGAG AAGGACGCCT TTTTGCTAAA ACACGTGAGG 
AGGAACAAGC TGGGATATGT GAGCGTTAAG CTACTCACAT CCTTCAAAAA GGTGAAACAT 
CTTACACGGG ACTGGAGAAC CACAGCACAT GCTTTGAAGT ATTCAGTGGT CCTTGAGTTG 
AATGAGGACC ACCGGAAGGT GAGGAGGACC ACCCCCGTCC CACTGTTCCC CAACGAGAAC 
CTCCCCAGCA AGATGCTCCT GGTCTATGAT CTCTACTTGT CTCCTAAGCT GTGGGCTCTG 
GCCACCCCCC AGAAGAATGG AAGGGTGCAA GAGAAGGTGA TGGAACACCT GCTCAAGCTT 
TTTGGGACTT TTGGAGTCAT CTCATCAGTG CGGATCCTCA AACCTGGGAG AGAGCTGCCC 
CCTGACATCC GGAGGATCAG CAGCCGCTAC AGCCAAGTGG GGACCCAGGA GTGCGCCATC 
GTGGAGTTCG AGGAGGTGGA AGCAGCCATC AAAGCCCATG AGTTCATGAT CACAGAATCT 
CAGGGCAAAG AGAACATGAA AGCTGTCCTG ATTGGTATGA AGCCACCCAA AAAGAAACCT 
GCCAAAGACA AAAATCATGA CGAGGAGCCC ACTGCGAGCA TCCACCTGAA CAAGTCCCTG 
AACAAGAGAG TCGAGGAGCT TCAGTACATG GGTGATGAGT CTTCTGCCAA CAGCTCCTCT 
GACCCCGAGA GCAACCCCAC ATCCCCTATG GCGGGCCGAC GGCACGCGGC CACCAACAAG 
CTCAGCCCGT CTGGCCACCA GAATCTCTTT CTGAGTCCAA ATGCCTCCCC GTGCACAAGT 
CCTTGGAGCA GCCCCTTGGC CCAACGCAAA GGCGTTTCCA GAAAGTCCCC ACTGGCGGAG 
GAAGGTAGAC TGAACTGCAG CACCAGCCCT GAGATCTTCC GCAAGTGTAT GGATTATTCC 
TCTGACAGCA GCGTCACTCC CTCTGGCAGC CCCTGGGTCC GGAGGCGTCG CCAAGCCGAG 
ATGGGGACCC AGGAGAAAAG CCCCGGTACG AGTCCCCTGC TCTCCCGGAA GATGCAGACT 
GCAGATGGGC TACCCGTAGG GGTGCTGAGG TTGCCCAGGG GTCCTGACAA CACCAGAGGA 
TTTCATGGCC ATGAGAGGAG CAGGGCCTGT GTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060827.2
CDS	70..1545
Translation	MAQSGGEARPGPKTAVQIRVAIQEAEDVDELEDEEEGAETRGAGDPARYLSPGWGSASEEEPSRGHSGTTASGGENEREDLEQEWKPPDEELIKKLVDQIEFYFSDENLEKDAFLLKHVRRNKLGYVSVKLLTSFKKVKHLTRDWRTTAHALKYSVVLELNEDHRKVRRTTPVPLFPNENLPSKMLLVYDLYLSPKLWALATPQKNGRVQEKVMEHLLKLFGTFGVISSVRILKPGRELPPDIRRISSRYSQVGTQECAIVEFEEVEAAIKAHEFMITESQGKENMKAVLIGMKPPKKKPAKDKNHDEEPTASIHLNKSLNKRVEELQYMGDESSANSSSDPESNPTSPMAGRRHAATNKLSPSGHQNLFLSPNASPCTSPWSSPLAQRKGVSRKSPLAEEGRLNCSTSPEIFRKCMDYSSDSSVTPSGSPWVRRRRQAEMGTQEKSPGTSPLLSRKMQTADGLPVGVLRLPRGPDNTRGFHGHERSRACV

Target ORF information:

RefSeq Version	NM_018357.4
Organism	Homo sapiens(human)
Definition	Homo sapiens La ribonucleoprotein 6, translational regulator (LARP6), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018357.4

ORF Insert Sequence:

ATGGCCCAGT CCGGCGGGGA GGCTCGGCCC GGGCCCAAGA CGGCGGTGCA GATCCGCGTC 
GCCATCCAGG AGGCCGAGGA CGTGGACGAG TTGGAGGACG AGGAGGAGGG GGCGGAGACT 
CGGGGCGCCG GGGACCCGGC CCGGTACCTC AGCCCCGGCT GGGGCAGCGC GAGCGAGGAG 
GAGCCGAGCC GCGGGCACAG TGGCACCACT GCAAGTGGAG GTGAGAACGA GCGTGAGGAC 
CTGGAGCAGG AGTGGAAGCC CCCGGATGAG GAGTTGATCA AGAAACTGGT GGATCAGATC 
GAATTCTACT TTTCTGATGA AAACCTGGAG AAGGACGCCT TTTTGCTAAA ACACGTGAGG 
AGGAACAAGC TGGGATATGT GAGCGTTAAG CTACTCACAT CCTTCAAAAA GGTGAAACAT 
CTTACACGGG ACTGGAGAAC CACAGCACAT GCTTTGAAGT ATTCAGTGGT CCTTGAGTTG 
AATGAGGACC ACCGGAAGGT GAGGAGGACC ACCCCCGTCC CACTGTTCCC CAACGAGAAC 
CTCCCCAGCA AGATGCTCCT GGTCTATGAT CTCTACTTGT CTCCTAAGCT GTGGGCTCTG 
GCCACCCCCC AGAAGAATGG AAGGGTGCAA GAGAAGGTGA TGGAACACCT GCTCAAGCTT 
TTTGGGACTT TTGGAGTCAT CTCATCAGTG CGGATCCTCA AACCTGGGAG AGAGCTGCCC 
CCTGACATCC GGAGGATCAG CAGCCGCTAC AGCCAAGTGG GGACCCAGGA GTGCGCCATC 
GTGGAGTTCG AGGAGGTGGA AGCAGCCATC AAAGCCCATG AGTTCATGAT CACAGAATCT 
CAGGGCAAAG AGAACATGAA AGCTGTCCTG ATTGGTATGA AGCCACCCAA AAAGAAACCT 
GCCAAAGACA AAAATCATGA CGAGGAGCCC ACTGCGAGCA TCCACCTGAA CAAGTCCCTG 
AACAAGAGAG TCGAGGAGCT TCAGTACATG GGTGATGAGT CTTCTGCCAA CAGCTCCTCT 
GACCCCGAGA GCAACCCCAC ATCCCCTATG GCGGGCCGAC GGCACGCGGC CACCAACAAG 
CTCAGCCCGT CTGGCCACCA GAATCTCTTT CTGAGTCCAA ATGCCTCCCC GTGCACAAGT 
CCTTGGAGCA GCCCCTTGGC CCAACGCAAA GGCGTTTCCA GAAAGTCCCC ACTGGCGGAG 
GAAGGTAGAC TGAACTGCAG CACCAGCCCT GAGATCTTCC GCAAGTGTAT GGATTATTCC 
TCTGACAGCA GCGTCACTCC CTCTGGCAGC CCCTGGGTCC GGAGGCGTCG CCAAGCCGAG 
ATGGGGACCC AGGAGAAAAG CCCCGGTACG AGTCCCCTGC TCTCCCGGAA GATGCAGACT 
GCAGATGGGC TACCCGTAGG GGTGCTGAGG TTGCCCAGGG GTCCTGACAA CACCAGAGGA 
TTTCATGGCC ATGAGAGGAG CAGGGCCTGT GTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LARP6 ( NM_001286679.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001273608.1 Homo sapiens La ribonucleoprotein domain family member 6 (LARP6), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu27637
Clone ID Related Accession (Same CDS sequence)	NM_001286679.1 , NM_001286679.2
Accession Version	NM_001286679.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 924bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-15
Organism	Homo sapiens(human)
Product	la-related protein 6 isoform 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA715263.1, AL833876.1 and AI376944.1. Transcript Variant: This variant (3) differs in the 5' UTR, lacks part of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (3) has a shorter N-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DA715263.1, SRR1803617.307754.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2144335 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTCCTGG TCTATGATCT CTACTTGTCT CCTAAGCTGT GGGCTCTGGC CACCCCCCAG 
AAGAATGGAA GGGTGCAAGA GAAGGTGATG GAACACCTGC TCAAGCTTTT TGGGACTTTT 
GGAGTCATCT CATCAGTGCG GATCCTCAAA CCTGGGAGAG AGCTGCCCCC TGACATCCGG 
AGGATCAGCA GCCGCTACAG CCAAGTGGGG ACCCAGGAGT GCGCCATCGT GGAGTTCGAG 
GAGGTGGAAG CAGCCATCAA AGCCCATGAG TTCATGATCA CAGAATCTCA GGGCAAAGAG 
AACATGAAAG CTGTCCTGAT TGGTATGAAG CCACCCAAAA AGAAACCTGC CAAAGACAAA 
AATCATGACG AGGAGCCCAC TGCGAGCATC CACCTGAACA AGTCCCTGAA CAAGAGAGTC 
GAGGAGCTTC AGTACATGGG TGATGAGTCT TCTGCCAACA GCTCCTCTGA CCCCGAGAGC 
AACCCCACAT CCCCTATGGC GGGCCGACGG CACGCGGCCA CCAACAAGCT CAGCCCGTCT 
GGCCACCAGA ATCTCTTTCT GAGTCCAAAT GCCTCCCCGT GCACAAGTCC TTGGAGCAGC 
CCCTTGGCCC AACGCAAAGG CGTTTCCAGA AAGTCCCCAC TGGCGGAGGA AGGTAGACTG 
AACTGCAGCA CCAGCCCTGA GATCTTCCGC AAGTGTATGG ATTATTCCTC TGACAGCAGC 
GTCACTCCCT CTGGCAGCCC CTGGGTCCGG AGGCGTCGCC AAGCCGAGAT GGGGACCCAG 
GAGAAAAGCC CCGGTACGAG TCCCCTGCTC TCCCGGAAGA TGCAGACTGC AGATGGGCTA 
CCCGTAGGGG TGCTGAGGTT GCCCAGGGGT CCTGACAACA CCAGAGGATT TCATGGCCAT 
GAGAGGAGCA GGGCCTGTGT ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001273608.1
CDS	465..1388
Translation	MLLVYDLYLSPKLWALATPQKNGRVQEKVMEHLLKLFGTFGVISSVRILKPGRELPPDIRRISSRYSQVGTQECAIVEFEEVEAAIKAHEFMITESQGKENMKAVLIGMKPPKKKPAKDKNHDEEPTASIHLNKSLNKRVEELQYMGDESSANSSSDPESNPTSPMAGRRHAATNKLSPSGHQNLFLSPNASPCTSPWSSPLAQRKGVSRKSPLAEEGRLNCSTSPEIFRKCMDYSSDSSVTPSGSPWVRRRRQAEMGTQEKSPGTSPLLSRKMQTADGLPVGVLRLPRGPDNTRGFHGHERSRACV

Target ORF information:

RefSeq Version	NM_001286679.1
Organism	Homo sapiens(human)
Definition	Homo sapiens La ribonucleoprotein domain family member 6 (LARP6), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001286679.1

ORF Insert Sequence:

ATGCTCCTGG TCTATGATCT CTACTTGTCT CCTAAGCTGT GGGCTCTGGC CACCCCCCAG 
AAGAATGGAA GGGTGCAAGA GAAGGTGATG GAACACCTGC TCAAGCTTTT TGGGACTTTT 
GGAGTCATCT CATCAGTGCG GATCCTCAAA CCTGGGAGAG AGCTGCCCCC TGACATCCGG 
AGGATCAGCA GCCGCTACAG CCAAGTGGGG ACCCAGGAGT GCGCCATCGT GGAGTTCGAG 
GAGGTGGAAG CAGCCATCAA AGCCCATGAG TTCATGATCA CAGAATCTCA GGGCAAAGAG 
AACATGAAAG CTGTCCTGAT TGGTATGAAG CCACCCAAAA AGAAACCTGC CAAAGACAAA 
AATCATGACG AGGAGCCCAC TGCGAGCATC CACCTGAACA AGTCCCTGAA CAAGAGAGTC 
GAGGAGCTTC AGTACATGGG TGATGAGTCT TCTGCCAACA GCTCCTCTGA CCCCGAGAGC 
AACCCCACAT CCCCTATGGC GGGCCGACGG CACGCGGCCA CCAACAAGCT CAGCCCGTCT 
GGCCACCAGA ATCTCTTTCT GAGTCCAAAT GCCTCCCCGT GCACAAGTCC TTGGAGCAGC 
CCCTTGGCCC AACGCAAAGG CGTTTCCAGA AAGTCCCCAC TGGCGGAGGA AGGTAGACTG 
AACTGCAGCA CCAGCCCTGA GATCTTCCGC AAGTGTATGG ATTATTCCTC TGACAGCAGC 
GTCACTCCCT CTGGCAGCCC CTGGGTCCGG AGGCGTCGCC AAGCCGAGAT GGGGACCCAG 
GAGAAAAGCC CCGGTACGAG TCCCCTGCTC TCCCGGAAGA TGCAGACTGC AGATGGGCTA 
CCCGTAGGGG TGCTGAGGTT GCCCAGGGGT CCTGACAACA CCAGAGGATT TCATGGCCAT 
GAGAGGAGCA GGGCCTGTGT ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LARP6 ( NM_001286679.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001273608.1 Homo sapiens La ribonucleoprotein 6, translational regulator (LARP6), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu27637
Clone ID Related Accession (Same CDS sequence)	NM_001286679.1 , NM_001286679.2
Accession Version	NM_001286679.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 924bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-28
Organism	Homo sapiens(human)
Product	la-related protein 6 isoform 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC090868.4, DA715263.1, AL833876.1, AI376944.1 and AC009269.6. On May 31, 2019 this sequence version replaced NM_001286679.1. Transcript Variant: This variant (3) differs in the 5' UTR, lacks part of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (3) has a shorter N-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.307754.1, DA715263.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2144335 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTCCTGG TCTATGATCT CTACTTGTCT CCTAAGCTGT GGGCTCTGGC CACCCCCCAG 
AAGAATGGAA GGGTGCAAGA GAAGGTGATG GAACACCTGC TCAAGCTTTT TGGGACTTTT 
GGAGTCATCT CATCAGTGCG GATCCTCAAA CCTGGGAGAG AGCTGCCCCC TGACATCCGG 
AGGATCAGCA GCCGCTACAG CCAAGTGGGG ACCCAGGAGT GCGCCATCGT GGAGTTCGAG 
GAGGTGGAAG CAGCCATCAA AGCCCATGAG TTCATGATCA CAGAATCTCA GGGCAAAGAG 
AACATGAAAG CTGTCCTGAT TGGTATGAAG CCACCCAAAA AGAAACCTGC CAAAGACAAA 
AATCATGACG AGGAGCCCAC TGCGAGCATC CACCTGAACA AGTCCCTGAA CAAGAGAGTC 
GAGGAGCTTC AGTACATGGG TGATGAGTCT TCTGCCAACA GCTCCTCTGA CCCCGAGAGC 
AACCCCACAT CCCCTATGGC GGGCCGACGG CACGCGGCCA CCAACAAGCT CAGCCCGTCT 
GGCCACCAGA ATCTCTTTCT GAGTCCAAAT GCCTCCCCGT GCACAAGTCC TTGGAGCAGC 
CCCTTGGCCC AACGCAAAGG CGTTTCCAGA AAGTCCCCAC TGGCGGAGGA AGGTAGACTG 
AACTGCAGCA CCAGCCCTGA GATCTTCCGC AAGTGTATGG ATTATTCCTC TGACAGCAGC 
GTCACTCCCT CTGGCAGCCC CTGGGTCCGG AGGCGTCGCC AAGCCGAGAT GGGGACCCAG 
GAGAAAAGCC CCGGTACGAG TCCCCTGCTC TCCCGGAAGA TGCAGACTGC AGATGGGCTA 
CCCGTAGGGG TGCTGAGGTT GCCCAGGGGT CCTGACAACA CCAGAGGATT TCATGGCCAT 
GAGAGGAGCA GGGCCTGTGT ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001273608.1
CDS	825..1748
Translation	MLLVYDLYLSPKLWALATPQKNGRVQEKVMEHLLKLFGTFGVISSVRILKPGRELPPDIRRISSRYSQVGTQECAIVEFEEVEAAIKAHEFMITESQGKENMKAVLIGMKPPKKKPAKDKNHDEEPTASIHLNKSLNKRVEELQYMGDESSANSSSDPESNPTSPMAGRRHAATNKLSPSGHQNLFLSPNASPCTSPWSSPLAQRKGVSRKSPLAEEGRLNCSTSPEIFRKCMDYSSDSSVTPSGSPWVRRRRQAEMGTQEKSPGTSPLLSRKMQTADGLPVGVLRLPRGPDNTRGFHGHERSRACV

Target ORF information:

RefSeq Version	NM_001286679.2
Organism	Homo sapiens(human)
Definition	Homo sapiens La ribonucleoprotein 6, translational regulator (LARP6), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001286679.2

ORF Insert Sequence:

ATGCTCCTGG TCTATGATCT CTACTTGTCT CCTAAGCTGT GGGCTCTGGC CACCCCCCAG 
AAGAATGGAA GGGTGCAAGA GAAGGTGATG GAACACCTGC TCAAGCTTTT TGGGACTTTT 
GGAGTCATCT CATCAGTGCG GATCCTCAAA CCTGGGAGAG AGCTGCCCCC TGACATCCGG 
AGGATCAGCA GCCGCTACAG CCAAGTGGGG ACCCAGGAGT GCGCCATCGT GGAGTTCGAG 
GAGGTGGAAG CAGCCATCAA AGCCCATGAG TTCATGATCA CAGAATCTCA GGGCAAAGAG 
AACATGAAAG CTGTCCTGAT TGGTATGAAG CCACCCAAAA AGAAACCTGC CAAAGACAAA 
AATCATGACG AGGAGCCCAC TGCGAGCATC CACCTGAACA AGTCCCTGAA CAAGAGAGTC 
GAGGAGCTTC AGTACATGGG TGATGAGTCT TCTGCCAACA GCTCCTCTGA CCCCGAGAGC 
AACCCCACAT CCCCTATGGC GGGCCGACGG CACGCGGCCA CCAACAAGCT CAGCCCGTCT 
GGCCACCAGA ATCTCTTTCT GAGTCCAAAT GCCTCCCCGT GCACAAGTCC TTGGAGCAGC 
CCCTTGGCCC AACGCAAAGG CGTTTCCAGA AAGTCCCCAC TGGCGGAGGA AGGTAGACTG 
AACTGCAGCA CCAGCCCTGA GATCTTCCGC AAGTGTATGG ATTATTCCTC TGACAGCAGC 
GTCACTCCCT CTGGCAGCCC CTGGGTCCGG AGGCGTCGCC AAGCCGAGAT GGGGACCCAG 
GAGAAAAGCC CCGGTACGAG TCCCCTGCTC TCCCGGAAGA TGCAGACTGC AGATGGGCTA 
CCCGTAGGGG TGCTGAGGTT GCCCAGGGGT CCTGACAACA CCAGAGGATT TCATGGCCAT 
GAGAGGAGCA GGGCCTGTGT ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LARP6 ( NM_197958.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_932062.1 Homo sapiens La ribonucleoprotein domain family member 6 (LARP6), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu02438
Clone ID Related Accession (Same CDS sequence)	NM_197958.2 , NM_197958.3
Accession Version	NM_197958.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 282bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Homo sapiens(human)
Product	la-related protein 6 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DN992782.1 and BC039153.1. On Nov 14, 2013 this sequence version replaced NM_197958.1. Transcript Variant: This variant (2) lacks several exons and uses an alternate 3' terminal exon, compared to variant 1. The encoded isoform (2) has a shorter and distinct C-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: CA431360.1, AI968173.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCCAGT CCGGCGGGGA GGCTCGGCCC GGGCCCAAGA CGGCGGTGCA GATCCGCGTC 
GCCATCCAGG AGGCCGAGGA CGTGGACGAG TTGGAGGACG AGGAGGAGGG GGCGGAGACT 
CGGGGCGCCG GGGACCCGGC CCGGTACCTC AGCCCCGGCT GGGGCAGCGC GAGCGAGGAG 
GAGCCGAGCC GCGGGCACAG GAATAGGAGC TCGGTGAATT CAAGGACCAT GCTTGCTTCG 
TTCATTGTAT CTTCAGCACC TAGCACAGCA CCCAGCACAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_932062.1
CDS	178..459
Translation	MAQSGGEARPGPKTAVQIRVAIQEAEDVDELEDEEEGAETRGAGDPARYLSPGWGSASEEEPSRGHRNRSSVNSRTMLASFIVSSAPSTAPST

Target ORF information:

RefSeq Version	NM_197958.2
Organism	Homo sapiens(human)
Definition	Homo sapiens La ribonucleoprotein domain family member 6 (LARP6), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_197958.2

ORF Insert Sequence:

ATGGCCCAGT CCGGCGGGGA GGCTCGGCCC GGGCCCAAGA CGGCGGTGCA GATCCGCGTC 
GCCATCCAGG AGGCCGAGGA CGTGGACGAG TTGGAGGACG AGGAGGAGGG GGCGGAGACT 
CGGGGCGCCG GGGACCCGGC CCGGTACCTC AGCCCCGGCT GGGGCAGCGC GAGCGAGGAG 
GAGCCGAGCC GCGGGCACAG GAATAGGAGC TCGGTGAATT CAAGGACCAT GCTTGCTTCG 
TTCATTGTAT CTTCAGCACC TAGCACAGCA CCCAGCACAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LARP6 ( NM_197958.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_932062.1 Homo sapiens La ribonucleoprotein 6, translational regulator (LARP6), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu02438
Clone ID Related Accession (Same CDS sequence)	NM_197958.2 , NM_197958.3
Accession Version	NM_197958.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 282bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-28
Organism	Homo sapiens(human)
Product	la-related protein 6 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DN992782.1 and BC039153.1. On Jun 1, 2019 this sequence version replaced NM_197958.2. Transcript Variant: This variant (2) lacks several exons and uses an alternate 3' terminal exon, compared to variant 1. The encoded isoform (2) has a shorter and distinct C-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DRR138520.771785.1, DRR138512.167795.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCCAGT CCGGCGGGGA GGCTCGGCCC GGGCCCAAGA CGGCGGTGCA GATCCGCGTC 
GCCATCCAGG AGGCCGAGGA CGTGGACGAG TTGGAGGACG AGGAGGAGGG GGCGGAGACT 
CGGGGCGCCG GGGACCCGGC CCGGTACCTC AGCCCCGGCT GGGGCAGCGC GAGCGAGGAG 
GAGCCGAGCC GCGGGCACAG GAATAGGAGC TCGGTGAATT CAAGGACCAT GCTTGCTTCG 
TTCATTGTAT CTTCAGCACC TAGCACAGCA CCCAGCACAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_932062.1
CDS	70..351
Translation	MAQSGGEARPGPKTAVQIRVAIQEAEDVDELEDEEEGAETRGAGDPARYLSPGWGSASEEEPSRGHRNRSSVNSRTMLASFIVSSAPSTAPST

Target ORF information:

RefSeq Version	NM_197958.3
Organism	Homo sapiens(human)
Definition	Homo sapiens La ribonucleoprotein 6, translational regulator (LARP6), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_197958.3

ORF Insert Sequence:

ATGGCCCAGT CCGGCGGGGA GGCTCGGCCC GGGCCCAAGA CGGCGGTGCA GATCCGCGTC 
GCCATCCAGG AGGCCGAGGA CGTGGACGAG TTGGAGGACG AGGAGGAGGG GGCGGAGACT 
CGGGGCGCCG GGGACCCGGC CCGGTACCTC AGCCCCGGCT GGGGCAGCGC GAGCGAGGAG 
GAGCCGAGCC GCGGGCACAG GAATAGGAGC TCGGTGAATT CAAGGACCAT GCTTGCTTCG 
TTCATTGTAT CTTCAGCACC TAGCACAGCA CCCAGCACAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The La and related RNA-binding proteins (LARPs): structures, functions, and evolving perspectives.
Wiley interdisciplinary reviews. RNA8(6)(2017 Nov)
Maraia RJ,Mattijssen S,Cruz-Gallardo I,Conte MR

mTORC1 phosphorylates LARP6 to stimulate type I collagen expression.
Scientific reports741173(2017 Jan)
Zhang Y,Stefanovic B

Akt mediated phosphorylation of LARP6; critical step in biosynthesis of type I collagen.
Scientific reports622597(2016 Mar)
Zhang Y,Stefanovic B

Synergic interplay of the La motif, RRM1 and the interdomain linker of LARP6 in the recognition of collagen mRNA expands the RNA binding repertoire of the La module.
Nucleic acids research43(1)645-60(2015 Jan)
Martino L,Pennell S,Kelly G,Busi B,Brown P,Atkinson RA,Salisbury NJ,Ooi ZH,See KW,Smerdon SJ,Alfano C,Bui TT,Conte MR

Characterization of binding of LARP6 to the 5' stem-loop of collagen mRNAs: implications for synthesis of type I collagen.
RNA biology11(11)1386-401(2014)
Stefanovic L,Longo L,Zhang Y,Stefanovic B

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

LARP6 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報