Gene Symbol | NEIL3 |
Entrez Gene ID | 55247 |
Full Name | nei like DNA glycosylase 3 |
Synonyms | FGP2,FPG2,NEI3,ZGRF3,hFPG2,hNEI3 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226]).[supplied by OMIM, Mar 2008]. |
Disorder MIM: |