SLC47A1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SLC47A1
Entrez Gene ID	55244
Full Name	solute carrier family 47 member 1
Synonyms	MATE1
General protein information	Preferred Names solute carrier family 47 member 1 Names multidrug and toxin extrusion protein 1 MATE-1 hMATE-1 multidrug and toxin extrusion 1 solute carrier family 47 (multidrug and toxin extrusion), member 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17p11.2
Summary	This gene is located within the Smith-Magenis syndrome region on chromosome 17. It encodes a protein of unknown function. [provided by RefSeq, Jul 2008].
Disorder MIM:	609832

mRNA and Protein(s)

mRNA	Protein	Name
NM_018242.3	NP_060712.2	multidrug and toxin extrusion protein 1
NM_018242.2	NP_060712.2	multidrug and toxin extrusion protein 1

Pathways from BioSystems

Homologies

	LOC703544	XP_002800377.1
Neurospora crassa	NCU07720	XP_961970.2
Oryza sativa (rice)	Os10g0344900	NP_001064393.1
Schizosaccharomyces pombe (fission yeast)	SPCC4B3.13	NP_588077.1
Arabidopsis thaliana (thale cress)	AT2G34360	NP_180983.4
Oryza sativa (rice)	Os10g0345100	NP_001064394.1
Oryza sativa (rice)	Os06g0495500	NP_001057690.1
Xenopus tropicalis (tropical clawed frog)	LOC100498310	XP_002934402.2
Homo sapiens (human)	SLC47A1	NP_060712.2
Bos taurus (cattle)	SLC47A1	XP_002695911.2
Saccharomyces cerevisiae (baker's yeast)	YDR338C	NP_010625.1
Eremothecium gossypii	AGOS_AEL099W	NP_984762.2
Magnaporthe oryzae (rice blast fungus)	MGG_04182	XP_003719641.1
Canis lupus familiaris (dog)	SLC47A1	XP_003639084.2
Mus musculus (house mouse)	Slc47a1	NP_080459.2
Rattus norvegicus (Norway rat)	Slc47a1	NP_001014140.1
Schizosaccharomyces pombe (fission yeast)	SPAC323.07c	NP_594377.1
Oryza sativa (rice)	Os06g0494400	NP_001057687.1
Oryza sativa (rice)	Os06g0495100	NP_001057689.1
Pan troglodytes (chimpanzee)	SLC47A1	XP_001144887.1
Kluyveromyces lactis	KLLA0A06952g	XP_451308.1
Arabidopsis thaliana (thale cress)	AT5G52450	NP_200058.1
Arabidopsis thaliana (thale cress)	AT1G73700	NP_177511.1

Gene Ontology
Bibliography

Related articles in PubMed

Relationship between DNA Methylation in the 5' CpG Island of the
Tanaka T, Hirota T, Ieiri I
Molecular pharmacology93(1)1-7(2018 Jan)

Potential role of polymorphisms in the transporter genes ENT1 and MATE1/OCT2 in predicting TAS-102 efficacy and toxicity in patients with refractory metastatic colorectal cancer.
Suenaga M, Schirripa M, Cao S, Zhang W, Yang D, Dadduzio V, Salvatore L, Borelli B, Pietrantonio F, Ning Y, Okazaki S, Berger MD, Miyamoto Y, Gopez R Jr, Barzi A, Yamaguchi T, Loupakis F, Lenz HJ
European journal of cancer (Oxford, England : 1990)86197-206(2017 11)

Differential increments of basal glucagon-like-1 peptide concentration among SLC47A1 rs2289669 genotypes were associated with inter-individual variability in glycaemic response to metformin in Chinese people with newly diagnosed Type 2 diabetes.
Liang H, Xu W, Zhou L, Yang W, Weng J
Diabetic medicine : a journal of the British Diabetic Association34(7)987-992(2017 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The 5' CpG island of SLC47A1 acts as an enhancer for SLC47A1, and DNA methylation in the CpG island plays a role in interindividual differences in hepatic SLC47A1 expression.
Title: Relationship between DNA Methylation in the 5' CpG Island of the

The combination of ENT1, MATE1 and OCT2 SNPs may serve as a predictive and prognostic marker in metastatic colorectal carcinoma patients treated with TAS-102.
Title: Potential role of polymorphisms in the transporter genes ENT1 and MATE1/OCT2 in predicting TAS-102 efficacy and toxicity in patients with refractory metastatic colorectal cancer.

substrate identity exerts comparatively little influence on ligand interaction with MATE1.
Title: Lack of Influence of Substrate on Ligand Interaction with the Human Multidrug and Toxin Extruder, MATE1.

MATE1 is the major transporter for the cellular uptake of imatinib and crucial for the therapeutic success in CML patients. We suggest that the detailed analysis of MATE1 expression levels and mutations could be a predictor for the response to imatinib therapy.
Title: MATE1 regulates cellular uptake and sensitivity to imatinib in CML patients.

MATE1 polymorphisms were associated with hematological toxicity in non-small cell lung cancer patients.
Title: Associations of genetic polymorphisms of the transporters organic cation transporter 2 (OCT2), multidrug and toxin extrusion 1 (MATE1), and ATP-binding cassette subfamily C member 2 (ABCC2) with platinum-based chemotherapy response and toxicity in non-small cell lung cancer patients.

The following SLC47A1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SLC47A1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu10141	NM_018242.3 Latest version!	Homo sapiens solute carrier family 47 member 1 (SLC47A1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
View Old Accession Versions >>
OHu10141	NM_018242.2	Homo sapiens solute carrier family 47 member 1 (SLC47A1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SLC47A1 ( NM_018242.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_060712.2 Homo sapiens solute carrier family 47 member 1 (SLC47A1), mRNA.

Price & Availability↑

CloneID	OHu10141
Clone ID Related Accession (Same CDS sequence)	NM_018242.3 , NM_018242.2
Accession Version	NM_018242.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1713bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-25
Organism	Homo sapiens(human)
Product	multidrug and toxin extrusion protein 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC025627.13. On Nov 25, 2018 this sequence version replaced NM_018242.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK001709.1, SRR1803616.165350.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000270570.8/ ENSP00000270570.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAAGCTC CTGAGGAGCC CGCGCCAGTG CGCGGAGGCC CGGAGGCCAC CCTTGAGGTC 
CGTGGGTCGC GCTGCTTGCG GCTGTCCGCC TTCCGAGAAG AGCTGCGGGC GCTCTTGGTC 
CTGGCTGGCC CCGCGTTCTT GGTTCAGCTG ATGGTGTTCC TGATCAGCTT CATAAGCTCC 
GTGTTCTGTG GCCACCTGGG CAAGCTGGAG CTGGATGCAG TCACGCTGGC AATCGCGGTT 
ATCAATGTCA CTGGTGTCTC AGTGGGATTC GGCTTATCTT CTGCCTGTGA CACCCTCATC 
TCCCAGACGT ACGGGAGCCA GAACCTGAAG CACGTGGGCG TGATCCTGCA GCGGAGTGCG 
CTCGTCCTGC TCCTCTGCTG CTTCCCCTGC TGGGCGCTCT TTCTCAACAC CCAGCACATC 
CTGCTGCTCT TCAGGCAGGA CCCAGATGTG TCCAGGCTTA CCCAGACCTA TGTCACGATC 
TTCATTCCAG CTCTTCCTGC AACCTTTCTT TATATGTTAC AAGTTAAATA TTTGCTCAAC 
CAGGGAATTG TACTGCCCCA GATCGTAACT GGAGTTGCAG CCAACCTTGT CAATGCCCTC 
GCCAACTATC TGTTTCTCCA TCAACTGCAT CTTGGGGTGA TAGGCTCTGC ACTGGCAAAC 
TTGATTTCCC AGTACACCCT GGCTCTACTC CTCTTTCTCT ACATCCTCGG GAAAAAACTG 
CATCAAGCTA CATGGGGAGG CTGGTCCCTC GAGTGCCTGC AGGACTGGGC CTCCTTCCTC 
CGCCTGGCCA TCCCCAGCAT GCTCATGCTG TGCATGGAGT GGTGGGCCTA TGAGGTCGGG 
AGCTTCCTCA GTGGCATCCT CGGCATGGTG GAGCTGGGCG CTCAGTCCAT CGTGTATGAA 
CTGGCCATCA TTGTGTACAT GGTCCCTGCA GGCTTCAGTG TGGCTGCCAG TGTCCGGGTA 
GGAAACGCTC TGGGTGCTGG AGACATGGAG CAGGCACGGA AGTCCTCTAC CGTTTCCCTG 
CTGATTACAG TGCTCTTTGC TGTAGCCTTC AGTGTCCTGC TGTTAAGCTG TAAGGATCAC 
GTGGGGTACA TTTTTACTAC CGACCGAGAC ATCATTAATC TGGTGGCTCA GGTGGTTCCA 
ATTTATGCTG TTTCCCACCT CTTTGAAGCT CTTGCTTGCA CGAGTGGTGG TGTTCTGAGG 
GGGAGTGGAA ATCAGAAGGT TGGAGCCATT GTGAATACCA TTGGGTACTA TGTGGTTGGC 
CTCCCCATCG GGATCGCGCT GATGTTTGCA ACCACACTTG GAGTGATGGG TCTGTGGTCA 
GGGATCATCA TCTGTACAGT CTTTCAAGCT GTGTGTTTTC TAGGCTTTAT TATTCAGCTA 
AATTGGAAAA AAGCCTGTCA GCAGGCTCAG GTACACGCCA ATTTGAAAGT AAACAACGTG 
CCTCGGAGTG GGAATTCTGC TCTCCCTCAG GATCCGCTTC ACCCAGGGTG CCCTGAAAAC 
CTTGAAGGAA TTTTAACGAA CGATGTTGGA AAGACAGGCG AGCCTCAGTC AGATCAGCAG 
ATGCGCCAAG AAGAACCTTT GCCGGAACAT CCACAGGACG GCGCTAAATT GTCCAGGAAA 
CAGCTGGTGC TGCGGCGAGG GCTTCTGCTC CTGGGGGTCT TCTTAATCTT GCTGGTGGGG 
ATTTTAGTGA GATTCTATGT CAGAATTCAG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060712.2
CDS	87..1799
Translation	MEAPEEPAPVRGGPEATLEVRGSRCLRLSAFREELRALLVLAGPAFLVQLMVFLISFISSVFCGHLGKLELDAVTLAIAVINVTGVSVGFGLSSACDTLISQTYGSQNLKHVGVILQRSALVLLLCCFPCWALFLNTQHILLLFRQDPDVSRLTQTYVTIFIPALPATFLYMLQVKYLLNQGIVLPQIVTGVAANLVNALANYLFLHQLHLGVIGSALANLISQYTLALLLFLYILGKKLHQATWGGWSLECLQDWASFLRLAIPSMLMLCMEWWAYEVGSFLSGILGMVELGAQSIVYELAIIVYMVPAGFSVAASVRVGNALGAGDMEQARKSSTVSLLITVLFAVAFSVLLLSCKDHVGYIFTTDRDIINLVAQVVPIYAVSHLFEALACTSGGVLRGSGNQKVGAIVNTIGYYVVGLPIGIALMFATTLGVMGLWSGIIICTVFQAVCFLGFIIQLNWKKACQQAQVHANLKVNNVPRSGNSALPQDPLHPGCPENLEGILTNDVGKTGEPQSDQQMRQEEPLPEHPQDGAKLSRKQLVLRRGLLLLGVFLILLVGILVRFYVRIQ

Target ORF information:

RefSeq Version	NM_018242.3
Organism	Homo sapiens(human)
Definition	Homo sapiens solute carrier family 47 member 1 (SLC47A1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018242.3

ORF Insert Sequence:

ATGGAAGCTC CTGAGGAGCC CGCGCCAGTG CGCGGAGGCC CGGAGGCCAC CCTTGAGGTC 
CGTGGGTCGC GCTGCTTGCG GCTGTCCGCC TTCCGAGAAG AGCTGCGGGC GCTCTTGGTC 
CTGGCTGGCC CCGCGTTCTT GGTTCAGCTG ATGGTGTTCC TGATCAGCTT CATAAGCTCC 
GTGTTCTGTG GCCACCTGGG CAAGCTGGAG CTGGATGCAG TCACGCTGGC AATCGCGGTT 
ATCAATGTCA CTGGTGTCTC AGTGGGATTC GGCTTATCTT CTGCCTGTGA CACCCTCATC 
TCCCAGACGT ACGGGAGCCA GAACCTGAAG CACGTGGGCG TGATCCTGCA GCGGAGTGCG 
CTCGTCCTGC TCCTCTGCTG CTTCCCCTGC TGGGCGCTCT TTCTCAACAC CCAGCACATC 
CTGCTGCTCT TCAGGCAGGA CCCAGATGTG TCCAGGCTTA CCCAGACCTA TGTCACGATC 
TTCATTCCAG CTCTTCCTGC AACCTTTCTT TATATGTTAC AAGTTAAATA TTTGCTCAAC 
CAGGGAATTG TACTGCCCCA GATCGTAACT GGAGTTGCAG CCAACCTTGT CAATGCCCTC 
GCCAACTATC TGTTTCTCCA TCAACTGCAT CTTGGGGTGA TAGGCTCTGC ACTGGCAAAC 
TTGATTTCCC AGTACACCCT GGCTCTACTC CTCTTTCTCT ACATCCTCGG GAAAAAACTG 
CATCAAGCTA CATGGGGAGG CTGGTCCCTC GAGTGCCTGC AGGACTGGGC CTCCTTCCTC 
CGCCTGGCCA TCCCCAGCAT GCTCATGCTG TGCATGGAGT GGTGGGCCTA TGAGGTCGGG 
AGCTTCCTCA GTGGCATCCT CGGCATGGTG GAGCTGGGCG CTCAGTCCAT CGTGTATGAA 
CTGGCCATCA TTGTGTACAT GGTCCCTGCA GGCTTCAGTG TGGCTGCCAG TGTCCGGGTA 
GGAAACGCTC TGGGTGCTGG AGACATGGAG CAGGCACGGA AGTCCTCTAC CGTTTCCCTG 
CTGATTACAG TGCTCTTTGC TGTAGCCTTC AGTGTCCTGC TGTTAAGCTG TAAGGATCAC 
GTGGGGTACA TTTTTACTAC CGACCGAGAC ATCATTAATC TGGTGGCTCA GGTGGTTCCA 
ATTTATGCTG TTTCCCACCT CTTTGAAGCT CTTGCTTGCA CGAGTGGTGG TGTTCTGAGG 
GGGAGTGGAA ATCAGAAGGT TGGAGCCATT GTGAATACCA TTGGGTACTA TGTGGTTGGC 
CTCCCCATCG GGATCGCGCT GATGTTTGCA ACCACACTTG GAGTGATGGG TCTGTGGTCA 
GGGATCATCA TCTGTACAGT CTTTCAAGCT GTGTGTTTTC TAGGCTTTAT TATTCAGCTA 
AATTGGAAAA AAGCCTGTCA GCAGGCTCAG GTACACGCCA ATTTGAAAGT AAACAACGTG 
CCTCGGAGTG GGAATTCTGC TCTCCCTCAG GATCCGCTTC ACCCAGGGTG CCCTGAAAAC 
CTTGAAGGAA TTTTAACGAA CGATGTTGGA AAGACAGGCG AGCCTCAGTC AGATCAGCAG 
ATGCGCCAAG AAGAACCTTT GCCGGAACAT CCACAGGACG GCGCTAAATT GTCCAGGAAA 
CAGCTGGTGC TGCGGCGAGG GCTTCTGCTC CTGGGGGTCT TCTTAATCTT GCTGGTGGGG 
ATTTTAGTGA GATTCTATGT CAGAATTCAG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SLC47A1 ( NM_018242.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_060712.2 Homo sapiens solute carrier family 47 member 1 (SLC47A1), mRNA.

Price & Availability↑

CloneID	OHu10141
Clone ID Related Accession (Same CDS sequence)	NM_018242.3 , NM_018242.2
Accession Version	NM_018242.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1713bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-10
Organism	Homo sapiens(human)
Product	multidrug and toxin extrusion protein 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK001709.1. On Sep 16, 2002 this sequence version replaced NM_018242.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK001709.1, SRR1803616.165350.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAAGCTC CTGAGGAGCC CGCGCCAGTG CGCGGAGGCC CGGAGGCCAC CCTTGAGGTC 
CGTGGGTCGC GCTGCTTGCG GCTGTCCGCC TTCCGAGAAG AGCTGCGGGC GCTCTTGGTC 
CTGGCTGGCC CCGCGTTCTT GGTTCAGCTG ATGGTGTTCC TGATCAGCTT CATAAGCTCC 
GTGTTCTGTG GCCACCTGGG CAAGCTGGAG CTGGATGCAG TCACGCTGGC AATCGCGGTT 
ATCAATGTCA CTGGTGTCTC AGTGGGATTC GGCTTATCTT CTGCCTGTGA CACCCTCATC 
TCCCAGACGT ACGGGAGCCA GAACCTGAAG CACGTGGGCG TGATCCTGCA GCGGAGTGCG 
CTCGTCCTGC TCCTCTGCTG CTTCCCCTGC TGGGCGCTCT TTCTCAACAC CCAGCACATC 
CTGCTGCTCT TCAGGCAGGA CCCAGATGTG TCCAGGCTTA CCCAGACCTA TGTCACGATC 
TTCATTCCAG CTCTTCCTGC AACCTTTCTT TATATGTTAC AAGTTAAATA TTTGCTCAAC 
CAGGGAATTG TACTGCCCCA GATCGTAACT GGAGTTGCAG CCAACCTTGT CAATGCCCTC 
GCCAACTATC TGTTTCTCCA TCAACTGCAT CTTGGGGTGA TAGGCTCTGC ACTGGCAAAC 
TTGATTTCCC AGTACACCCT GGCTCTACTC CTCTTTCTCT ACATCCTCGG GAAAAAACTG 
CATCAAGCTA CATGGGGAGG CTGGTCCCTC GAGTGCCTGC AGGACTGGGC CTCCTTCCTC 
CGCCTGGCCA TCCCCAGCAT GCTCATGCTG TGCATGGAGT GGTGGGCCTA TGAGGTCGGG 
AGCTTCCTCA GTGGCATCCT CGGCATGGTG GAGCTGGGCG CTCAGTCCAT CGTGTATGAA 
CTGGCCATCA TTGTGTACAT GGTCCCTGCA GGCTTCAGTG TGGCTGCCAG TGTCCGGGTA 
GGAAACGCTC TGGGTGCTGG AGACATGGAG CAGGCACGGA AGTCCTCTAC CGTTTCCCTG 
CTGATTACAG TGCTCTTTGC TGTAGCCTTC AGTGTCCTGC TGTTAAGCTG TAAGGATCAC 
GTGGGGTACA TTTTTACTAC CGACCGAGAC ATCATTAATC TGGTGGCTCA GGTGGTTCCA 
ATTTATGCTG TTTCCCACCT CTTTGAAGCT CTTGCTTGCA CGAGTGGTGG TGTTCTGAGG 
GGGAGTGGAA ATCAGAAGGT TGGAGCCATT GTGAATACCA TTGGGTACTA TGTGGTTGGC 
CTCCCCATCG GGATCGCGCT GATGTTTGCA ACCACACTTG GAGTGATGGG TCTGTGGTCA 
GGGATCATCA TCTGTACAGT CTTTCAAGCT GTGTGTTTTC TAGGCTTTAT TATTCAGCTA 
AATTGGAAAA AAGCCTGTCA GCAGGCTCAG GTACACGCCA ATTTGAAAGT AAACAACGTG 
CCTCGGAGTG GGAATTCTGC TCTCCCTCAG GATCCGCTTC ACCCAGGGTG CCCTGAAAAC 
CTTGAAGGAA TTTTAACGAA CGATGTTGGA AAGACAGGCG AGCCTCAGTC AGATCAGCAG 
ATGCGCCAAG AAGAACCTTT GCCGGAACAT CCACAGGACG GCGCTAAATT GTCCAGGAAA 
CAGCTGGTGC TGCGGCGAGG GCTTCTGCTC CTGGGGGTCT TCTTAATCTT GCTGGTGGGG 
ATTTTAGTGA GATTCTATGT CAGAATTCAG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060712.2
CDS	87..1799
Translation	MEAPEEPAPVRGGPEATLEVRGSRCLRLSAFREELRALLVLAGPAFLVQLMVFLISFISSVFCGHLGKLELDAVTLAIAVINVTGVSVGFGLSSACDTLISQTYGSQNLKHVGVILQRSALVLLLCCFPCWALFLNTQHILLLFRQDPDVSRLTQTYVTIFIPALPATFLYMLQVKYLLNQGIVLPQIVTGVAANLVNALANYLFLHQLHLGVIGSALANLISQYTLALLLFLYILGKKLHQATWGGWSLECLQDWASFLRLAIPSMLMLCMEWWAYEVGSFLSGILGMVELGAQSIVYELAIIVYMVPAGFSVAASVRVGNALGAGDMEQARKSSTVSLLITVLFAVAFSVLLLSCKDHVGYIFTTDRDIINLVAQVVPIYAVSHLFEALACTSGGVLRGSGNQKVGAIVNTIGYYVVGLPIGIALMFATTLGVMGLWSGIIICTVFQAVCFLGFIIQLNWKKACQQAQVHANLKVNNVPRSGNSALPQDPLHPGCPENLEGILTNDVGKTGEPQSDQQMRQEEPLPEHPQDGAKLSRKQLVLRRGLLLLGVFLILLVGILVRFYVRIQ

Target ORF information:

RefSeq Version	NM_018242.2
Organism	Homo sapiens(human)
Definition	Homo sapiens solute carrier family 47 member 1 (SLC47A1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018242.2

ORF Insert Sequence:

ATGGAAGCTC CTGAGGAGCC CGCGCCAGTG CGCGGAGGCC CGGAGGCCAC CCTTGAGGTC 
CGTGGGTCGC GCTGCTTGCG GCTGTCCGCC TTCCGAGAAG AGCTGCGGGC GCTCTTGGTC 
CTGGCTGGCC CCGCGTTCTT GGTTCAGCTG ATGGTGTTCC TGATCAGCTT CATAAGCTCC 
GTGTTCTGTG GCCACCTGGG CAAGCTGGAG CTGGATGCAG TCACGCTGGC AATCGCGGTT 
ATCAATGTCA CTGGTGTCTC AGTGGGATTC GGCTTATCTT CTGCCTGTGA CACCCTCATC 
TCCCAGACGT ACGGGAGCCA GAACCTGAAG CACGTGGGCG TGATCCTGCA GCGGAGTGCG 
CTCGTCCTGC TCCTCTGCTG CTTCCCCTGC TGGGCGCTCT TTCTCAACAC CCAGCACATC 
CTGCTGCTCT TCAGGCAGGA CCCAGATGTG TCCAGGCTTA CCCAGACCTA TGTCACGATC 
TTCATTCCAG CTCTTCCTGC AACCTTTCTT TATATGTTAC AAGTTAAATA TTTGCTCAAC 
CAGGGAATTG TACTGCCCCA GATCGTAACT GGAGTTGCAG CCAACCTTGT CAATGCCCTC 
GCCAACTATC TGTTTCTCCA TCAACTGCAT CTTGGGGTGA TAGGCTCTGC ACTGGCAAAC 
TTGATTTCCC AGTACACCCT GGCTCTACTC CTCTTTCTCT ACATCCTCGG GAAAAAACTG 
CATCAAGCTA CATGGGGAGG CTGGTCCCTC GAGTGCCTGC AGGACTGGGC CTCCTTCCTC 
CGCCTGGCCA TCCCCAGCAT GCTCATGCTG TGCATGGAGT GGTGGGCCTA TGAGGTCGGG 
AGCTTCCTCA GTGGCATCCT CGGCATGGTG GAGCTGGGCG CTCAGTCCAT CGTGTATGAA 
CTGGCCATCA TTGTGTACAT GGTCCCTGCA GGCTTCAGTG TGGCTGCCAG TGTCCGGGTA 
GGAAACGCTC TGGGTGCTGG AGACATGGAG CAGGCACGGA AGTCCTCTAC CGTTTCCCTG 
CTGATTACAG TGCTCTTTGC TGTAGCCTTC AGTGTCCTGC TGTTAAGCTG TAAGGATCAC 
GTGGGGTACA TTTTTACTAC CGACCGAGAC ATCATTAATC TGGTGGCTCA GGTGGTTCCA 
ATTTATGCTG TTTCCCACCT CTTTGAAGCT CTTGCTTGCA CGAGTGGTGG TGTTCTGAGG 
GGGAGTGGAA ATCAGAAGGT TGGAGCCATT GTGAATACCA TTGGGTACTA TGTGGTTGGC 
CTCCCCATCG GGATCGCGCT GATGTTTGCA ACCACACTTG GAGTGATGGG TCTGTGGTCA 
GGGATCATCA TCTGTACAGT CTTTCAAGCT GTGTGTTTTC TAGGCTTTAT TATTCAGCTA 
AATTGGAAAA AAGCCTGTCA GCAGGCTCAG GTACACGCCA ATTTGAAAGT AAACAACGTG 
CCTCGGAGTG GGAATTCTGC TCTCCCTCAG GATCCGCTTC ACCCAGGGTG CCCTGAAAAC 
CTTGAAGGAA TTTTAACGAA CGATGTTGGA AAGACAGGCG AGCCTCAGTC AGATCAGCAG 
ATGCGCCAAG AAGAACCTTT GCCGGAACAT CCACAGGACG GCGCTAAATT GTCCAGGAAA 
CAGCTGGTGC TGCGGCGAGG GCTTCTGCTC CTGGGGGTCT TCTTAATCTT GCTGGTGGGG 
ATTTTAGTGA GATTCTATGT CAGAATTCAG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Relationship between DNA Methylation in the 5' CpG Island of the
Molecular pharmacology93(1)1-7(2018 Jan)
Tanaka T,Hirota T,Ieiri I

Potential role of polymorphisms in the transporter genes ENT1 and MATE1/OCT2 in predicting TAS-102 efficacy and toxicity in patients with refractory metastatic colorectal cancer.
European journal of cancer (Oxford, England : 1990)86197-206(2017 11)
Suenaga M,Schirripa M,Cao S,Zhang W,Yang D,Dadduzio V,Salvatore L,Borelli B,Pietrantonio F,Ning Y,Okazaki S,Berger MD,Miyamoto Y,Gopez R Jr,Barzi A,Yamaguchi T,Loupakis F,Lenz HJ

Differential increments of basal glucagon-like-1 peptide concentration among SLC47A1 rs2289669 genotypes were associated with inter-individual variability in glycaemic response to metformin in Chinese people with newly diagnosed Type 2 diabetes.
Diabetic medicine : a journal of the British Diabetic Association34(7)987-992(2017 Jul)
Liang H,Xu W,Zhou L,Yang W,Weng J

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SLC47A1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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