PLEKHG6 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PLEKHG6
Entrez Gene ID	55200
Full Name	pleckstrin homology and RhoGEF domain containing G6
Synonyms	MyoGEF
General protein information	Preferred Names pleckstrin homology and RhoGEF domain containing G6 Names pleckstrin homology domain-containing family G member 6 PH domain-containing family G member 6 myosin II interacting GEF myosin interacting guanine nucleotide exchange factor pleckstrin homology domain containing, family G (with RhoGef domain) member 6
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 12 Map Location: 12p13.31
Disorder MIM:	611743

mRNA and Protein(s)

mRNA	Protein	Name
NM_001144857.1	NP_001138329.1	pleckstrin homology domain-containing family G member 6 isoform b
NM_018173.3	NP_060643.2	pleckstrin homology domain-containing family G member 6 isoform a
XM_005253704.4	XP_005253761.1	pleckstrin homology domain-containing family G member 6 isoform X1
XM_017019555.1	XP_016875044.1	pleckstrin homology domain-containing family G member 6 isoform X2
NM_001144856.1	NP_001138328.1	pleckstrin homology domain-containing family G member 6 isoform a
XM_006718985.3	XP_006719048.1	pleckstrin homology domain-containing family G member 6 isoform X3
XM_011520967.2	XP_011519269.1	pleckstrin homology domain-containing family G member 6 isoform X4

Pathways from BioSystems

Homologies

Homo sapiens (human)	PLEKHG6	NP_060643.2
Pan troglodytes (chimpanzee)	PLEKHG6	XP_522333.2
	PLEKHG6	XP_001118229.2
Canis lupus familiaris (dog)	PLEKHG6	XP_534913.2
Mus musculus (house mouse)	Plekhg6	NP_941006.2
Rattus norvegicus (Norway rat)	Plekhg6	XP_006237465.1
Bos taurus (cattle)	PLEKHG6	XP_003586191.1

Gene Ontology
Bibliography

Related articles in PubMed

Myosin II-interacting guanine nucleotide exchange factor (MYOGEF) promotes bleb retraction via stimulating cortex reassembly at the bleb membrane.
Jiao M, Wu D, Wei Q
Molecular biology of the cell(2018 Jan)

Intramolecular interactions between the Dbl homology (DH) domain and the carboxyl-terminal region of myosin II-interacting guanine nucleotide exchange factor (MyoGEF) act as an autoinhibitory mechanism for the regulation of MyoGEF functions.
Wu D, Jiao M, Zu S, Sollecito CC, Jimenez-Cowell K, Mold AJ, Kennedy RM, Wei Q
The Journal of biological chemistry289(49)34033-48(2014 Dec)

Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk.
Zhang B, Jia WH, Matsuda K, Kweon SS, Matsuo K, Xiang YB, Shin A, Jee SH, Kim DH, Cai Q, Long J, Shi J, Wen W, Yang G, Zhang Y, Li C, Li B, Guo Y, Ren Z, Ji BT, Pan ZZ, Takahashi A, Shin MH, Matsuda F, Gao YT, Oh JH, Kim S, Ahn YO, , Chan AT, Chang-Claude J, Slattery ML, , Gruber SB, Schumacher FR, Stenzel SL, , Casey G, Kim HR, Jeong JY, Park JW, Li HL, Hosono S, Cho SH, Kubo M, Shu XO, Zeng YX, Zheng W
Nature genetics46(6)533-42(2014 Jun)

Phosphorylation of myosin II-interacting guanine nucleotide exchange factor (MyoGEF) at threonine 544 by aurora B kinase promotes the binding of polo-like kinase 1 to MyoGEF.
Wu D, Asiedu M, Matsumura F, Wei Q
The Journal of biological chemistry289(10)7142-50(2014 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Intramolecular interactions between MyoGEF domains act as an autoinhibitory mechanism for the regulation of MyoGEF functions.
Title: Intramolecular interactions between the Dbl homology (DH) domain and the carboxyl-terminal region of myosin II-interacting guanine nucleotide exchange factor (MyoGEF) act as an autoinhibitory mechanism for the regulation of MyoGEF functions.

Taken together, these results suggest that aurora B coordinates with Plk1 to regulate MyoGEF activation and localization, thus contributing to the regulation of cytokinesis.
Title: Phosphorylation of myosin II-interacting guanine nucleotide exchange factor (MyoGEF) at threonine 544 by aurora B kinase promotes the binding of polo-like kinase 1 to MyoGEF.

GIPC1-MyoGEF complex formation plays an important role in regulating MDA-MB-231 breast cancer cell polarization and invasion.
Title: GIPC1 interacts with MyoGEF and promotes MDA-MB-231 breast cancer cell invasion.

MyoGEF cooperates with nonmuscle myosin IIA to regulate the polarity and invasion activity of breast cancer cells through activation of RhoA and RhoC.
Title: Myosin-interacting guanine exchange factor (MyoGEF) regulates the invasion activity of MDA-MB-231 breast cancer cells through activation of RhoA and RhoC.

Plk1 can regulate MyoGEF activity and localization, contributing to the regulation of cytokinesis
Title: Phosphorylation of MyoGEF on Thr-574 by Plk1 promotes MyoGEF localization to the central spindle.

The following PLEKHG6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PLEKHG6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu02721	NM_001144856.1 Latest version!	Homo sapiens pleckstrin homology and RhoGEF domain containing G6 (PLEKHG6), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$265.30 $379.00
OHu02721	NM_018173.3 Latest version!	Homo sapiens pleckstrin homology and RhoGEF domain containing G6 (PLEKHG6), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$265.30 $379.00
OHu08101	NM_001144857.1 Latest version!	Homo sapiens pleckstrin homology and RhoGEF domain containing G6 (PLEKHG6), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$538.30 $769.00
OHu02721	XM_005253704.4 Latest version!	Homo sapiens pleckstrin homology and RhoGEF domain containing G6 (PLEKHG6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$265.30 $379.00
OHu45977	XM_006718985.3 Latest version!	Homo sapiens pleckstrin homology and RhoGEF domain containing G6 (PLEKHG6), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OHu69149	XM_011520967.2 Latest version!	Homo sapiens pleckstrin homology and RhoGEF domain containing G6 (PLEKHG6), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OHu83931	XM_017019555.1 Latest version!	Homo sapiens pleckstrin homology and RhoGEF domain containing G6 (PLEKHG6), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PLEKHG6 ( NM_018173.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_060643.2 Homo sapiens pleckstrin homology and RhoGEF domain containing G6 (PLEKHG6), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu02721
Clone ID Related Accession (Same CDS sequence)	NM_018173.3 , XM_005253704.4 , NM_001144856.1
Accession Version	NM_018173.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2373bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-18
Organism	Homo sapiens(human)
Product	pleckstrin homology domain-containing family G member 6 isoform a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK001527.1, BC105961.1 and BU754580.1. On Jan 28, 2009 this sequence version replaced NM_018173.2. Transcript Variant: This variant (1) represents the shortest transcript but encodes the longer isoform (a). Variants 1 and 2 encode the same isoform. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK001527.1, BC104751.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142348, SAMEA2142680 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGGCCT TTGGTCCTCC ACATGAGGGC CCCCTCCAAG GACTCGTGGC CTCCCGCATT 
GAGACTTATG GGGGCCGGCA TCGAGCCTCT GCTCAGAGCA CTGCTGGCAG ACTCTATCCC 
CGAGGATACC CTGTGCTGGA TCCCAGTCGC CGACGCCTCC AGCAGTATGT CCCCTTTGCC 
AGGGGTTCTG GCCAGGCCCG AGGCCTGTCA CCCATGAGAC TGCGAGATCC AGAGCCCGAG 
AAGAGGCACG GGGGCCATGT GGGGGCTGGC CTGCTTCACT CCCCCAAACT CAAGGAACTC 
ACCAAGGCCC ATGAGCTGGA GGTGAGGCTG CACACTTTCA GCATGTTTGG GATGCCCCGG 
CTGCCCCCTG AGGACCGGCG GCACTGGGAG ATAGGAGAGG GTGGCGACAG TGGCCTGACC 
ATCGAGAAGT CCTGGAGGGA GCTGGTGCCT GGGCACAAGG AGATGAGCCA GGAGCTCTGC 
CACCAACAGG AGGCCCTGTG GGAGCTCCTG ACCACCGAGC TGATCTACGT GAGAAAGCTC 
AAGATCATGA CTGATCTGCT AGCCGCCGGC CTGCTGAACC TGCAGCGAGT GGGACTGCTG 
ATGGAAGTGT CAGCTGAGAC CCTGTTTGGA AATGTCCCCA GCCTGATTCG AACCCACCGG 
AGCTTTTGGG ATGAGGTGCT GGGGCCCACC CTGGAGGAGA CTCGGGCCTC GGGCCAGCCT 
CTGGACCCCA TTGGTCTGCA AAGTGGCTTC CTGACGTTTG GCCAGCGGTT CCACCCCTAT 
GTCCAGTACT GCCTCCGAGT GAAGCAGACC ATGGCTTACG CCCGAGAACA GCAAGAAACT 
AACCCTCTCT TCCATGCCTT CGTGCAGTGG TGTGAGAAGC ACAAGCGCTC TGGGAGGCAG 
ATGCTCTGTG ACTTGCTTAT CAAGCCCCAC CAGCGCATCA CCAAGTACCC ACTGCTGCTC 
CATGCTGTGC TCAAGAGGAG CCCCGAGGCA CGAGCCCAAG AGGCCCTGAA TGCCATGATT 
GAAGCCGTGG AGTCATTCCT GCGACACATC AATGGGCAGG TCCGCCAGGG CGAAGAGCAA 
GAGAGCTTGG CGGCTGCAGC ACAACGCATC GGGCCCTACG AGGTGCTGGA GCCACCCAGT 
GATGAGGTGG AGAAGAACCT GCGCCCATTC TCCACCCTGG ACCTGACGTC CCCCATGCTG 
GGGGTTGCAT CTGAGCACAC CAGACAGCTG CTGCTGGAGG GGCCTGTGCG AGTGAAGGAG 
GGACGAGAAG GGAAGCTGGA CGTGTACCTG TTCCTCTTCT CTGATGTGCT CCTTGTGACC 
AAGCCCCAGC GCAAGGCGGA CAAAGCCAAG GTCATCCGAC CCCCTCTCAT GCTGGAGAAG 
CTCGTGTGCC AACCCCTGCG AGACCCCAAC AGCTTCCTGC TGATCCACCT CACTGAATTC 
CAGTGTGTCT CCAGCGCCCT CCTTGTGCAC TGTCCCAGTC CTACAGACCG TGCCCAGTGG 
CTGGAGAAGA CCCAGCAGGC CCAGGCCGCC CTACAGAAGC TGAAGGCAGA GGAGTATGTT 
CAACAGAAGA GGGAGCTCCT GACCCTCTAT CGGGACCAGG ACAGGGAGTC CCCCAGCACC 
AGGCCCTCCA CGCCTTCCCT GGAGGGCTCT CAGAGCAGCG CAGAGGGGAG GACTCCTGAG 
TTCTCGACCA TTATCCCCCA CCTGGTGGTG ACAGAAGACA CAGATGAAGA TGCTCCCCTT 
GTGCCAGATG ATACCTCAGA CTCTGGCTAC GGCACTTTGA TCCCAGGCAC CCCCACGGGG 
TCCCGCTCCC CACTGAGCCG TCTACGCCAA AGAGCCCTTC GGCGGGACCC TCGCCTCACC 
TTCTCCACCC TGGAACTCCG GGACATCCCT CTGCGTCCCC ACCCTCCCGA CCCCCAAGCT 
CCTCAACGCC GAAGCGCCCC CGAACTGCCG GAAGGAATCC TAAAAGGAGG CAGTCTTCCC 
CAGGAAGACC CACCAACCTG GTCTGAGGAA GAAGATGGGG CCTCCGAGCG AGGGAATGTG 
GTGGTGGAAA CACTCCACAG GGCCCGGCTT CGGGGCCAGC TTCCCTCCTC CCCAACCCAT 
GCTGACTCTG CCGGGGAAAG CCCCTGGGAG TCCTCAGGGG AGGAGGAAGA AGAGGGGCCT 
CTGTTCCTGA AAGCTGGCCA CACATCCCTG CGCCCAATGC GGGCTGAGGA CATGCTCAGA 
GAGATCCGGG AGGAGCTGGC CAGCCAAAGG ATTGAGGGGG CCGAGGAGCC CCGGGACAGC 
AGGCCACGGA AGCTGACTCG GGCCCAGCTG CAGAGGATGC GGGGGCCCCA CATCATTCAG 
CTGGACACCC CTCTGTCCGC ATCAGAGGTA TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060643.2
CDS	149..2521
Translation	MKAFGPPHEGPLQGLVASRIETYGGRHRASAQSTAGRLYPRGYPVLDPSRRRLQQYVPFARGSGQARGLSPMRLRDPEPEKRHGGHVGAGLLHSPKLKELTKAHELEVRLHTFSMFGMPRLPPEDRRHWEIGEGGDSGLTIEKSWRELVPGHKEMSQELCHQQEALWELLTTELIYVRKLKIMTDLLAAGLLNLQRVGLLMEVSAETLFGNVPSLIRTHRSFWDEVLGPTLEETRASGQPLDPIGLQSGFLTFGQRFHPYVQYCLRVKQTMAYAREQQETNPLFHAFVQWCEKHKRSGRQMLCDLLIKPHQRITKYPLLLHAVLKRSPEARAQEALNAMIEAVESFLRHINGQVRQGEEQESLAAAAQRIGPYEVLEPPSDEVEKNLRPFSTLDLTSPMLGVASEHTRQLLLEGPVRVKEGREGKLDVYLFLFSDVLLVTKPQRKADKAKVIRPPLMLEKLVCQPLRDPNSFLLIHLTEFQCVSSALLVHCPSPTDRAQWLEKTQQAQAALQKLKAEEYVQQKRELLTLYRDQDRESPSTRPSTPSLEGSQSSAEGRTPEFSTIIPHLVVTEDTDEDAPLVPDDTSDSGYGTLIPGTPTGSRSPLSRLRQRALRRDPRLTFSTLELRDIPLRPHPPDPQAPQRRSAPELPEGILKGGSLPQEDPPTWSEEEDGASERGNVVVETLHRARLRGQLPSSPTHADSAGESPWESSGEEEEEGPLFLKAGHTSLRPMRAEDMLREIREELASQRIEGAEEPRDSRPRKLTRAQLQRMRGPHIIQLDTPLSASEV

Target ORF information:

RefSeq Version	NM_018173.3
Organism	Homo sapiens(human)
Definition	Homo sapiens pleckstrin homology and RhoGEF domain containing G6 (PLEKHG6), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018173.3

ORF Insert Sequence:

ATGAAGGCCT TTGGTCCTCC ACATGAGGGC CCCCTCCAAG GACTCGTGGC CTCCCGCATT 
GAGACTTATG GGGGCCGGCA TCGAGCCTCT GCTCAGAGCA CTGCTGGCAG ACTCTATCCC 
CGAGGATACC CTGTGCTGGA TCCCAGTCGC CGACGCCTCC AGCAGTATGT CCCCTTTGCC 
AGGGGTTCTG GCCAGGCCCG AGGCCTGTCA CCCATGAGAC TGCGAGATCC AGAGCCCGAG 
AAGAGGCACG GGGGCCATGT GGGGGCTGGC CTGCTTCACT CCCCCAAACT CAAGGAACTC 
ACCAAGGCCC ATGAGCTGGA GGTGAGGCTG CACACTTTCA GCATGTTTGG GATGCCCCGG 
CTGCCCCCTG AGGACCGGCG GCACTGGGAG ATAGGAGAGG GTGGCGACAG TGGCCTGACC 
ATCGAGAAGT CCTGGAGGGA GCTGGTGCCT GGGCACAAGG AGATGAGCCA GGAGCTCTGC 
CACCAACAGG AGGCCCTGTG GGAGCTCCTG ACCACCGAGC TGATCTACGT GAGAAAGCTC 
AAGATCATGA CTGATCTGCT AGCCGCCGGC CTGCTGAACC TGCAGCGAGT GGGACTGCTG 
ATGGAAGTGT CAGCTGAGAC CCTGTTTGGA AATGTCCCCA GCCTGATTCG AACCCACCGG 
AGCTTTTGGG ATGAGGTGCT GGGGCCCACC CTGGAGGAGA CTCGGGCCTC GGGCCAGCCT 
CTGGACCCCA TTGGTCTGCA AAGTGGCTTC CTGACGTTTG GCCAGCGGTT CCACCCCTAT 
GTCCAGTACT GCCTCCGAGT GAAGCAGACC ATGGCTTACG CCCGAGAACA GCAAGAAACT 
AACCCTCTCT TCCATGCCTT CGTGCAGTGG TGTGAGAAGC ACAAGCGCTC TGGGAGGCAG 
ATGCTCTGTG ACTTGCTTAT CAAGCCCCAC CAGCGCATCA CCAAGTACCC ACTGCTGCTC 
CATGCTGTGC TCAAGAGGAG CCCCGAGGCA CGAGCCCAAG AGGCCCTGAA TGCCATGATT 
GAAGCCGTGG AGTCATTCCT GCGACACATC AATGGGCAGG TCCGCCAGGG CGAAGAGCAA 
GAGAGCTTGG CGGCTGCAGC ACAACGCATC GGGCCCTACG AGGTGCTGGA GCCACCCAGT 
GATGAGGTGG AGAAGAACCT GCGCCCATTC TCCACCCTGG ACCTGACGTC CCCCATGCTG 
GGGGTTGCAT CTGAGCACAC CAGACAGCTG CTGCTGGAGG GGCCTGTGCG AGTGAAGGAG 
GGACGAGAAG GGAAGCTGGA CGTGTACCTG TTCCTCTTCT CTGATGTGCT CCTTGTGACC 
AAGCCCCAGC GCAAGGCGGA CAAAGCCAAG GTCATCCGAC CCCCTCTCAT GCTGGAGAAG 
CTCGTGTGCC AACCCCTGCG AGACCCCAAC AGCTTCCTGC TGATCCACCT CACTGAATTC 
CAGTGTGTCT CCAGCGCCCT CCTTGTGCAC TGTCCCAGTC CTACAGACCG TGCCCAGTGG 
CTGGAGAAGA CCCAGCAGGC CCAGGCCGCC CTACAGAAGC TGAAGGCAGA GGAGTATGTT 
CAACAGAAGA GGGAGCTCCT GACCCTCTAT CGGGACCAGG ACAGGGAGTC CCCCAGCACC 
AGGCCCTCCA CGCCTTCCCT GGAGGGCTCT CAGAGCAGCG CAGAGGGGAG GACTCCTGAG 
TTCTCGACCA TTATCCCCCA CCTGGTGGTG ACAGAAGACA CAGATGAAGA TGCTCCCCTT 
GTGCCAGATG ATACCTCAGA CTCTGGCTAC GGCACTTTGA TCCCAGGCAC CCCCACGGGG 
TCCCGCTCCC CACTGAGCCG TCTACGCCAA AGAGCCCTTC GGCGGGACCC TCGCCTCACC 
TTCTCCACCC TGGAACTCCG GGACATCCCT CTGCGTCCCC ACCCTCCCGA CCCCCAAGCT 
CCTCAACGCC GAAGCGCCCC CGAACTGCCG GAAGGAATCC TAAAAGGAGG CAGTCTTCCC 
CAGGAAGACC CACCAACCTG GTCTGAGGAA GAAGATGGGG CCTCCGAGCG AGGGAATGTG 
GTGGTGGAAA CACTCCACAG GGCCCGGCTT CGGGGCCAGC TTCCCTCCTC CCCAACCCAT 
GCTGACTCTG CCGGGGAAAG CCCCTGGGAG TCCTCAGGGG AGGAGGAAGA AGAGGGGCCT 
CTGTTCCTGA AAGCTGGCCA CACATCCCTG CGCCCAATGC GGGCTGAGGA CATGCTCAGA 
GAGATCCGGG AGGAGCTGGC CAGCCAAAGG ATTGAGGGGG CCGAGGAGCC CCGGGACAGC 
AGGCCACGGA AGCTGACTCG GGCCCAGCTG CAGAGGATGC GGGGGCCCCA CATCATTCAG 
CTGGACACCC CTCTGTCCGC ATCAGAGGTA TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PLEKHG6 ( NM_001144856.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001138328.1 Homo sapiens pleckstrin homology and RhoGEF domain containing G6 (PLEKHG6), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu02721
Clone ID Related Accession (Same CDS sequence)	NM_018173.3 , XM_005253704.4 , NM_001144856.1
Accession Version	NM_001144856.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2373bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-18
Organism	Homo sapiens(human)
Product	pleckstrin homology domain-containing family G member 6 isoform a
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK023741.1, AC006057.5, BC109095.2, AW001611.1 and BU754580.1. Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1 and 2 encode the same isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK023741.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAAGGCCT TTGGTCCTCC ACATGAGGGC CCCCTCCAAG GACTCGTGGC CTCCCGCATT 
GAGACTTATG GGGGCCGGCA TCGAGCCTCT GCTCAGAGCA CTGCTGGCAG ACTCTATCCC 
CGAGGATACC CTGTGCTGGA TCCCAGTCGC CGACGCCTCC AGCAGTATGT CCCCTTTGCC 
AGGGGTTCTG GCCAGGCCCG AGGCCTGTCA CCCATGAGAC TGCGAGATCC AGAGCCCGAG 
AAGAGGCACG GGGGCCATGT GGGGGCTGGC CTGCTTCACT CCCCCAAACT CAAGGAACTC 
ACCAAGGCCC ATGAGCTGGA GGTGAGGCTG CACACTTTCA GCATGTTTGG GATGCCCCGG 
CTGCCCCCTG AGGACCGGCG GCACTGGGAG ATAGGAGAGG GTGGCGACAG TGGCCTGACC 
ATCGAGAAGT CCTGGAGGGA GCTGGTGCCT GGGCACAAGG AGATGAGCCA GGAGCTCTGC 
CACCAACAGG AGGCCCTGTG GGAGCTCCTG ACCACCGAGC TGATCTACGT GAGAAAGCTC 
AAGATCATGA CTGATCTGCT AGCCGCCGGC CTGCTGAACC TGCAGCGAGT GGGACTGCTG 
ATGGAAGTGT CAGCTGAGAC CCTGTTTGGA AATGTCCCCA GCCTGATTCG AACCCACCGG 
AGCTTTTGGG ATGAGGTGCT GGGGCCCACC CTGGAGGAGA CTCGGGCCTC GGGCCAGCCT 
CTGGACCCCA TTGGTCTGCA AAGTGGCTTC CTGACGTTTG GCCAGCGGTT CCACCCCTAT 
GTCCAGTACT GCCTCCGAGT GAAGCAGACC ATGGCTTACG CCCGAGAACA GCAAGAAACT 
AACCCTCTCT TCCATGCCTT CGTGCAGTGG TGTGAGAAGC ACAAGCGCTC TGGGAGGCAG 
ATGCTCTGTG ACTTGCTTAT CAAGCCCCAC CAGCGCATCA CCAAGTACCC ACTGCTGCTC 
CATGCTGTGC TCAAGAGGAG CCCCGAGGCA CGAGCCCAAG AGGCCCTGAA TGCCATGATT 
GAAGCCGTGG AGTCATTCCT GCGACACATC AATGGGCAGG TCCGCCAGGG CGAAGAGCAA 
GAGAGCTTGG CGGCTGCAGC ACAACGCATC GGGCCCTACG AGGTGCTGGA GCCACCCAGT 
GATGAGGTGG AGAAGAACCT GCGCCCATTC TCCACCCTGG ACCTGACGTC CCCCATGCTG 
GGGGTTGCAT CTGAGCACAC CAGACAGCTG CTGCTGGAGG GGCCTGTGCG AGTGAAGGAG 
GGACGAGAAG GGAAGCTGGA CGTGTACCTG TTCCTCTTCT CTGATGTGCT CCTTGTGACC 
AAGCCCCAGC GCAAGGCGGA CAAAGCCAAG GTCATCCGAC CCCCTCTCAT GCTGGAGAAG 
CTCGTGTGCC AACCCCTGCG AGACCCCAAC AGCTTCCTGC TGATCCACCT CACTGAATTC 
CAGTGTGTCT CCAGCGCCCT CCTTGTGCAC TGTCCCAGTC CTACAGACCG TGCCCAGTGG 
CTGGAGAAGA CCCAGCAGGC CCAGGCCGCC CTACAGAAGC TGAAGGCAGA GGAGTATGTT 
CAACAGAAGA GGGAGCTCCT GACCCTCTAT CGGGACCAGG ACAGGGAGTC CCCCAGCACC 
AGGCCCTCCA CGCCTTCCCT GGAGGGCTCT CAGAGCAGCG CAGAGGGGAG GACTCCTGAG 
TTCTCGACCA TTATCCCCCA CCTGGTGGTG ACAGAAGACA CAGATGAAGA TGCTCCCCTT 
GTGCCAGATG ATACCTCAGA CTCTGGCTAC GGCACTTTGA TCCCAGGCAC CCCCACGGGG 
TCCCGCTCCC CACTGAGCCG TCTACGCCAA AGAGCCCTTC GGCGGGACCC TCGCCTCACC 
TTCTCCACCC TGGAACTCCG GGACATCCCT CTGCGTCCCC ACCCTCCCGA CCCCCAAGCT 
CCTCAACGCC GAAGCGCCCC CGAACTGCCG GAAGGAATCC TAAAAGGAGG CAGTCTTCCC 
CAGGAAGACC CACCAACCTG GTCTGAGGAA GAAGATGGGG CCTCCGAGCG AGGGAATGTG 
GTGGTGGAAA CACTCCACAG GGCCCGGCTT CGGGGCCAGC TTCCCTCCTC CCCAACCCAT 
GCTGACTCTG CCGGGGAAAG CCCCTGGGAG TCCTCAGGGG AGGAGGAAGA AGAGGGGCCT 
CTGTTCCTGA AAGCTGGCCA CACATCCCTG CGCCCAATGC GGGCTGAGGA CATGCTCAGA 
GAGATCCGGG AGGAGCTGGC CAGCCAAAGG ATTGAGGGGG CCGAGGAGCC CCGGGACAGC 
AGGCCACGGA AGCTGACTCG GGCCCAGCTG CAGAGGATGC GGGGGCCCCA CATCATTCAG 
CTGGACACCC CTCTGTCCGC ATCAGAGGTA TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001138328.1
CDS	231..2603
Translation	MKAFGPPHEGPLQGLVASRIETYGGRHRASAQSTAGRLYPRGYPVLDPSRRRLQQYVPFARGSGQARGLSPMRLRDPEPEKRHGGHVGAGLLHSPKLKELTKAHELEVRLHTFSMFGMPRLPPEDRRHWEIGEGGDSGLTIEKSWRELVPGHKEMSQELCHQQEALWELLTTELIYVRKLKIMTDLLAAGLLNLQRVGLLMEVSAETLFGNVPSLIRTHRSFWDEVLGPTLEETRASGQPLDPIGLQSGFLTFGQRFHPYVQYCLRVKQTMAYAREQQETNPLFHAFVQWCEKHKRSGRQMLCDLLIKPHQRITKYPLLLHAVLKRSPEARAQEALNAMIEAVESFLRHINGQVRQGEEQESLAAAAQRIGPYEVLEPPSDEVEKNLRPFSTLDLTSPMLGVASEHTRQLLLEGPVRVKEGREGKLDVYLFLFSDVLLVTKPQRKADKAKVIRPPLMLEKLVCQPLRDPNSFLLIHLTEFQCVSSALLVHCPSPTDRAQWLEKTQQAQAALQKLKAEEYVQQKRELLTLYRDQDRESPSTRPSTPSLEGSQSSAEGRTPEFSTIIPHLVVTEDTDEDAPLVPDDTSDSGYGTLIPGTPTGSRSPLSRLRQRALRRDPRLTFSTLELRDIPLRPHPPDPQAPQRRSAPELPEGILKGGSLPQEDPPTWSEEEDGASERGNVVVETLHRARLRGQLPSSPTHADSAGESPWESSGEEEEEGPLFLKAGHTSLRPMRAEDMLREIREELASQRIEGAEEPRDSRPRKLTRAQLQRMRGPHIIQLDTPLSASEV

Target ORF information:

RefSeq Version	NM_001144856.1
Organism	Homo sapiens(human)
Definition	Homo sapiens pleckstrin homology and RhoGEF domain containing G6 (PLEKHG6), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001144856.1

ORF Insert Sequence:

ATGAAGGCCT TTGGTCCTCC ACATGAGGGC CCCCTCCAAG GACTCGTGGC CTCCCGCATT 
GAGACTTATG GGGGCCGGCA TCGAGCCTCT GCTCAGAGCA CTGCTGGCAG ACTCTATCCC 
CGAGGATACC CTGTGCTGGA TCCCAGTCGC CGACGCCTCC AGCAGTATGT CCCCTTTGCC 
AGGGGTTCTG GCCAGGCCCG AGGCCTGTCA CCCATGAGAC TGCGAGATCC AGAGCCCGAG 
AAGAGGCACG GGGGCCATGT GGGGGCTGGC CTGCTTCACT CCCCCAAACT CAAGGAACTC 
ACCAAGGCCC ATGAGCTGGA GGTGAGGCTG CACACTTTCA GCATGTTTGG GATGCCCCGG 
CTGCCCCCTG AGGACCGGCG GCACTGGGAG ATAGGAGAGG GTGGCGACAG TGGCCTGACC 
ATCGAGAAGT CCTGGAGGGA GCTGGTGCCT GGGCACAAGG AGATGAGCCA GGAGCTCTGC 
CACCAACAGG AGGCCCTGTG GGAGCTCCTG ACCACCGAGC TGATCTACGT GAGAAAGCTC 
AAGATCATGA CTGATCTGCT AGCCGCCGGC CTGCTGAACC TGCAGCGAGT GGGACTGCTG 
ATGGAAGTGT CAGCTGAGAC CCTGTTTGGA AATGTCCCCA GCCTGATTCG AACCCACCGG 
AGCTTTTGGG ATGAGGTGCT GGGGCCCACC CTGGAGGAGA CTCGGGCCTC GGGCCAGCCT 
CTGGACCCCA TTGGTCTGCA AAGTGGCTTC CTGACGTTTG GCCAGCGGTT CCACCCCTAT 
GTCCAGTACT GCCTCCGAGT GAAGCAGACC ATGGCTTACG CCCGAGAACA GCAAGAAACT 
AACCCTCTCT TCCATGCCTT CGTGCAGTGG TGTGAGAAGC ACAAGCGCTC TGGGAGGCAG 
ATGCTCTGTG ACTTGCTTAT CAAGCCCCAC CAGCGCATCA CCAAGTACCC ACTGCTGCTC 
CATGCTGTGC TCAAGAGGAG CCCCGAGGCA CGAGCCCAAG AGGCCCTGAA TGCCATGATT 
GAAGCCGTGG AGTCATTCCT GCGACACATC AATGGGCAGG TCCGCCAGGG CGAAGAGCAA 
GAGAGCTTGG CGGCTGCAGC ACAACGCATC GGGCCCTACG AGGTGCTGGA GCCACCCAGT 
GATGAGGTGG AGAAGAACCT GCGCCCATTC TCCACCCTGG ACCTGACGTC CCCCATGCTG 
GGGGTTGCAT CTGAGCACAC CAGACAGCTG CTGCTGGAGG GGCCTGTGCG AGTGAAGGAG 
GGACGAGAAG GGAAGCTGGA CGTGTACCTG TTCCTCTTCT CTGATGTGCT CCTTGTGACC 
AAGCCCCAGC GCAAGGCGGA CAAAGCCAAG GTCATCCGAC CCCCTCTCAT GCTGGAGAAG 
CTCGTGTGCC AACCCCTGCG AGACCCCAAC AGCTTCCTGC TGATCCACCT CACTGAATTC 
CAGTGTGTCT CCAGCGCCCT CCTTGTGCAC TGTCCCAGTC CTACAGACCG TGCCCAGTGG 
CTGGAGAAGA CCCAGCAGGC CCAGGCCGCC CTACAGAAGC TGAAGGCAGA GGAGTATGTT 
CAACAGAAGA GGGAGCTCCT GACCCTCTAT CGGGACCAGG ACAGGGAGTC CCCCAGCACC 
AGGCCCTCCA CGCCTTCCCT GGAGGGCTCT CAGAGCAGCG CAGAGGGGAG GACTCCTGAG 
TTCTCGACCA TTATCCCCCA CCTGGTGGTG ACAGAAGACA CAGATGAAGA TGCTCCCCTT 
GTGCCAGATG ATACCTCAGA CTCTGGCTAC GGCACTTTGA TCCCAGGCAC CCCCACGGGG 
TCCCGCTCCC CACTGAGCCG TCTACGCCAA AGAGCCCTTC GGCGGGACCC TCGCCTCACC 
TTCTCCACCC TGGAACTCCG GGACATCCCT CTGCGTCCCC ACCCTCCCGA CCCCCAAGCT 
CCTCAACGCC GAAGCGCCCC CGAACTGCCG GAAGGAATCC TAAAAGGAGG CAGTCTTCCC 
CAGGAAGACC CACCAACCTG GTCTGAGGAA GAAGATGGGG CCTCCGAGCG AGGGAATGTG 
GTGGTGGAAA CACTCCACAG GGCCCGGCTT CGGGGCCAGC TTCCCTCCTC CCCAACCCAT 
GCTGACTCTG CCGGGGAAAG CCCCTGGGAG TCCTCAGGGG AGGAGGAAGA AGAGGGGCCT 
CTGTTCCTGA AAGCTGGCCA CACATCCCTG CGCCCAATGC GGGCTGAGGA CATGCTCAGA 
GAGATCCGGG AGGAGCTGGC CAGCCAAAGG ATTGAGGGGG CCGAGGAGCC CCGGGACAGC 
AGGCCACGGA AGCTGACTCG GGCCCAGCTG CAGAGGATGC GGGGGCCCCA CATCATTCAG 
CTGGACACCC CTCTGTCCGC ATCAGAGGTA TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PLEKHG6 ( NM_001144857.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001138329.1 Homo sapiens pleckstrin homology and RhoGEF domain containing G6 (PLEKHG6), transcript variant 3, mRNA.

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CloneID	OHu08101
Clone ID Related Accession (Same CDS sequence)	NM_001144857.1
Accession Version	NM_001144857.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2277bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-18
Organism	Homo sapiens(human)
Product	pleckstrin homology domain-containing family G member 6 isoform b
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK095373.1, AC006057.5, AW001611.1 and BU754580.1. Transcript Variant: This variant (3) differs in the 5' UTR and 5' coding region, compared to variant 1. The resulting protein (isoform b) has a shorter and distinct N-terminus, compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK095373.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2152568 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGATGCA GGCTGCACGC CCCTGGGGAG AAGGCTGCAC ATGATCCCAG TCGCCGACGC 
CTCCAGCAGT ATGTCCCCTT TGCCAGGGGT TCTGGCCAGG CCCGAGGCCT GTCACCCATG 
AGACTGCGAG ATCCAGAGCC CGAGAAGAGG CACGGGGGCC ATGTGGGGGC TGGCCTGCTT 
CACTCCCCCA AACTCAAGGA ACTCACCAAG GCCCATGAGC TGGAGGTGAG GCTGCACACT 
TTCAGCATGT TTGGGATGCC CCGGCTGCCC CCTGAGGACC GGCGGCACTG GGAGATAGGA 
GAGGGTGGCG ACAGTGGCCT GACCATCGAG AAGTCCTGGA GGGAGCTGGT GCCTGGGCAC 
AAGGAGATGA GCCAGGAGCT CTGCCACCAA CAGGAGGCCC TGTGGGAGCT CCTGACCACC 
GAGCTGATCT ACGTGAGAAA GCTCAAGATC ATGACTGATC TGCTAGCCGC CGGCCTGCTG 
AACCTGCAGC GAGTGGGACT GCTGATGGAA GTGTCAGCTG AGACCCTGTT TGGAAATGTC 
CCCAGCCTGA TTCGAACCCA CCGGAGCTTT TGGGATGAGG TGCTGGGGCC CACCCTGGAG 
GAGACTCGGG CCTCGGGCCA GCCTCTGGAC CCCATTGGTC TGCAAAGTGG CTTCCTGACG 
TTTGGCCAGC GGTTCCACCC CTATGTCCAG TACTGCCTCC GAGTGAAGCA GACCATGGCT 
TACGCCCGAG AACAGCAAGA AACTAACCCT CTCTTCCATG CCTTCGTGCA GTGGTGTGAG 
AAGCACAAGC GCTCTGGGAG GCAGATGCTC TGTGACTTGC TTATCAAGCC CCACCAGCGC 
ATCACCAAGT ACCCACTGCT GCTCCATGCT GTGCTCAAGA GGAGCCCCGA GGCACGAGCC 
CAAGAGGCCC TGAATGCCAT GATTGAAGCC GTGGAGTCAT TCCTGCGACA CATCAATGGG 
CAGGTCCGCC AGGGCGAAGA GCAAGAGAGC TTGGCGGCTG CAGCACAACG CATCGGGCCC 
TACGAGGTGC TGGAGCCACC CAGTGATGAG GTGGAGAAGA ACCTGCGCCC ATTCTCCACC 
CTGGACCTGA CGTCCCCCAT GCTGGGGGTT GCATCTGAGC ACACCAGACA GCTGCTGCTG 
GAGGGGCCTG TGCGAGTGAA GGAGGGACGA GAAGGGAAGC TGGACGTGTA CCTGTTCCTC 
TTCTCTGATG TGCTCCTTGT GACCAAGCCC CAGCGCAAGG CGGACAAAGC CAAGGTCATC 
CGACCCCCTC TCATGCTGGA GAAGCTCGTG TGCCAACCCC TGCGAGACCC CAACAGCTTC 
CTGCTGATCC ACCTCACTGA ATTCCAGTGT GTCTCCAGCG CCCTCCTTGT GCACTGTCCC 
AGTCCTACAG ACCGTGCCCA GTGGCTGGAG AAGACCCAGC AGGCCCAGGC CGCCCTACAG 
AAGCTGAAGG CAGAGGAGTA TGTTCAACAG AAGAGGGAGC TCCTGACCCT CTATCGGGAC 
CAGGACAGGG AGTCCCCCAG CACCAGGCCC TCCACGCCTT CCCTGGAGGG CTCTCAGAGC 
AGCGCAGAGG GGAGGACTCC TGAGTTCTCG ACCATTATCC CCCACCTGGT GGTGACAGAA 
GACACAGATG AAGATGCTCC CCTTGTGCCA GATGATACCT CAGACTCTGG CTACGGCACT 
TTGATCCCAG GCACCCCCAC GGGGTCCCGC TCCCCACTGA GCCGTCTACG CCAAAGAGCC 
CTTCGGCGGG ACCCTCGCCT CACCTTCTCC ACCCTGGAAC TCCGGGACAT CCCTCTGCGT 
CCCCACCCTC CCGACCCCCA AGCTCCTCAA CGCCGAAGCG CCCCCGAACT GCCGGAAGGA 
ATCCTAAAAG GAGGCAGTCT TCCCCAGGAA GACCCACCAA CCTGGTCTGA GGAAGAAGAT 
GGGGCCTCCG AGCGAGGGAA TGTGGTGGTG GAAACACTCC ACAGGGCCCG GCTTCGGGGC 
CAGCTTCCCT CCTCCCCAAC CCATGCTGAC TCTGCCGGGG AAAGCCCCTG GGAGTCCTCA 
GGGGAGGAGG AAGAAGAGGG GCCTCTGTTC CTGAAAGCTG GCCACACATC CCTGCGCCCA 
ATGCGGGCTG AGGACATGCT CAGAGAGATC CGGGAGGAGC TGGCCAGCCA AAGGATTGAG 
GGGGCCGAGG AGCCCCGGGA CAGCAGGCCA CGGAAGCTGA CTCGGGCCCA GCTGCAGAGG 
ATGCGGGGGC CCCACATCAT TCAGCTGGAC ACCCCTCTGT CCGCATCAGA GGTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001138329.1
CDS	495..2771
Translation	MGCRLHAPGEKAAHDPSRRRLQQYVPFARGSGQARGLSPMRLRDPEPEKRHGGHVGAGLLHSPKLKELTKAHELEVRLHTFSMFGMPRLPPEDRRHWEIGEGGDSGLTIEKSWRELVPGHKEMSQELCHQQEALWELLTTELIYVRKLKIMTDLLAAGLLNLQRVGLLMEVSAETLFGNVPSLIRTHRSFWDEVLGPTLEETRASGQPLDPIGLQSGFLTFGQRFHPYVQYCLRVKQTMAYAREQQETNPLFHAFVQWCEKHKRSGRQMLCDLLIKPHQRITKYPLLLHAVLKRSPEARAQEALNAMIEAVESFLRHINGQVRQGEEQESLAAAAQRIGPYEVLEPPSDEVEKNLRPFSTLDLTSPMLGVASEHTRQLLLEGPVRVKEGREGKLDVYLFLFSDVLLVTKPQRKADKAKVIRPPLMLEKLVCQPLRDPNSFLLIHLTEFQCVSSALLVHCPSPTDRAQWLEKTQQAQAALQKLKAEEYVQQKRELLTLYRDQDRESPSTRPSTPSLEGSQSSAEGRTPEFSTIIPHLVVTEDTDEDAPLVPDDTSDSGYGTLIPGTPTGSRSPLSRLRQRALRRDPRLTFSTLELRDIPLRPHPPDPQAPQRRSAPELPEGILKGGSLPQEDPPTWSEEEDGASERGNVVVETLHRARLRGQLPSSPTHADSAGESPWESSGEEEEEGPLFLKAGHTSLRPMRAEDMLREIREELASQRIEGAEEPRDSRPRKLTRAQLQRMRGPHIIQLDTPLSASEV

Target ORF information:

RefSeq Version	NM_001144857.1
Organism	Homo sapiens(human)
Definition	Homo sapiens pleckstrin homology and RhoGEF domain containing G6 (PLEKHG6), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001144857.1

ORF Insert Sequence:

ATGGGATGCA GGCTGCACGC CCCTGGGGAG AAGGCTGCAC ATGATCCCAG TCGCCGACGC 
CTCCAGCAGT ATGTCCCCTT TGCCAGGGGT TCTGGCCAGG CCCGAGGCCT GTCACCCATG 
AGACTGCGAG ATCCAGAGCC CGAGAAGAGG CACGGGGGCC ATGTGGGGGC TGGCCTGCTT 
CACTCCCCCA AACTCAAGGA ACTCACCAAG GCCCATGAGC TGGAGGTGAG GCTGCACACT 
TTCAGCATGT TTGGGATGCC CCGGCTGCCC CCTGAGGACC GGCGGCACTG GGAGATAGGA 
GAGGGTGGCG ACAGTGGCCT GACCATCGAG AAGTCCTGGA GGGAGCTGGT GCCTGGGCAC 
AAGGAGATGA GCCAGGAGCT CTGCCACCAA CAGGAGGCCC TGTGGGAGCT CCTGACCACC 
GAGCTGATCT ACGTGAGAAA GCTCAAGATC ATGACTGATC TGCTAGCCGC CGGCCTGCTG 
AACCTGCAGC GAGTGGGACT GCTGATGGAA GTGTCAGCTG AGACCCTGTT TGGAAATGTC 
CCCAGCCTGA TTCGAACCCA CCGGAGCTTT TGGGATGAGG TGCTGGGGCC CACCCTGGAG 
GAGACTCGGG CCTCGGGCCA GCCTCTGGAC CCCATTGGTC TGCAAAGTGG CTTCCTGACG 
TTTGGCCAGC GGTTCCACCC CTATGTCCAG TACTGCCTCC GAGTGAAGCA GACCATGGCT 
TACGCCCGAG AACAGCAAGA AACTAACCCT CTCTTCCATG CCTTCGTGCA GTGGTGTGAG 
AAGCACAAGC GCTCTGGGAG GCAGATGCTC TGTGACTTGC TTATCAAGCC CCACCAGCGC 
ATCACCAAGT ACCCACTGCT GCTCCATGCT GTGCTCAAGA GGAGCCCCGA GGCACGAGCC 
CAAGAGGCCC TGAATGCCAT GATTGAAGCC GTGGAGTCAT TCCTGCGACA CATCAATGGG 
CAGGTCCGCC AGGGCGAAGA GCAAGAGAGC TTGGCGGCTG CAGCACAACG CATCGGGCCC 
TACGAGGTGC TGGAGCCACC CAGTGATGAG GTGGAGAAGA ACCTGCGCCC ATTCTCCACC 
CTGGACCTGA CGTCCCCCAT GCTGGGGGTT GCATCTGAGC ACACCAGACA GCTGCTGCTG 
GAGGGGCCTG TGCGAGTGAA GGAGGGACGA GAAGGGAAGC TGGACGTGTA CCTGTTCCTC 
TTCTCTGATG TGCTCCTTGT GACCAAGCCC CAGCGCAAGG CGGACAAAGC CAAGGTCATC 
CGACCCCCTC TCATGCTGGA GAAGCTCGTG TGCCAACCCC TGCGAGACCC CAACAGCTTC 
CTGCTGATCC ACCTCACTGA ATTCCAGTGT GTCTCCAGCG CCCTCCTTGT GCACTGTCCC 
AGTCCTACAG ACCGTGCCCA GTGGCTGGAG AAGACCCAGC AGGCCCAGGC CGCCCTACAG 
AAGCTGAAGG CAGAGGAGTA TGTTCAACAG AAGAGGGAGC TCCTGACCCT CTATCGGGAC 
CAGGACAGGG AGTCCCCCAG CACCAGGCCC TCCACGCCTT CCCTGGAGGG CTCTCAGAGC 
AGCGCAGAGG GGAGGACTCC TGAGTTCTCG ACCATTATCC CCCACCTGGT GGTGACAGAA 
GACACAGATG AAGATGCTCC CCTTGTGCCA GATGATACCT CAGACTCTGG CTACGGCACT 
TTGATCCCAG GCACCCCCAC GGGGTCCCGC TCCCCACTGA GCCGTCTACG CCAAAGAGCC 
CTTCGGCGGG ACCCTCGCCT CACCTTCTCC ACCCTGGAAC TCCGGGACAT CCCTCTGCGT 
CCCCACCCTC CCGACCCCCA AGCTCCTCAA CGCCGAAGCG CCCCCGAACT GCCGGAAGGA 
ATCCTAAAAG GAGGCAGTCT TCCCCAGGAA GACCCACCAA CCTGGTCTGA GGAAGAAGAT 
GGGGCCTCCG AGCGAGGGAA TGTGGTGGTG GAAACACTCC ACAGGGCCCG GCTTCGGGGC 
CAGCTTCCCT CCTCCCCAAC CCATGCTGAC TCTGCCGGGG AAAGCCCCTG GGAGTCCTCA 
GGGGAGGAGG AAGAAGAGGG GCCTCTGTTC CTGAAAGCTG GCCACACATC CCTGCGCCCA 
ATGCGGGCTG AGGACATGCT CAGAGAGATC CGGGAGGAGC TGGCCAGCCA AAGGATTGAG 
GGGGCCGAGG AGCCCCGGGA CAGCAGGCCA CGGAAGCTGA CTCGGGCCCA GCTGCAGAGG 
ATGCGGGGGC CCCACATCAT TCAGCTGGAC ACCCCTCTGT CCGCATCAGA GGTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PLEKHG6 ( XM_005253704.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_005253761.1 Homo sapiens pleckstrin homology and RhoGEF domain containing G6 (PLEKHG6), transcript variant X1, mRNA.

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CloneID	OHu02721
Clone ID Related Accession (Same CDS sequence)	NM_018173.3 , XM_005253704.4 , NM_001144856.1
Accession Version	XM_005253704.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2373bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	pleckstrin homology domain-containing family G member 6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005253704.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGGCCT TTGGTCCTCC ACATGAGGGC CCCCTCCAAG GACTCGTGGC CTCCCGCATT 
GAGACTTATG GGGGCCGGCA TCGAGCCTCT GCTCAGAGCA CTGCTGGCAG ACTCTATCCC 
CGAGGATACC CTGTGCTGGA TCCCAGTCGC CGACGCCTCC AGCAGTATGT CCCCTTTGCC 
AGGGGTTCTG GCCAGGCCCG AGGCCTGTCA CCCATGAGAC TGCGAGATCC AGAGCCCGAG 
AAGAGGCACG GGGGCCATGT GGGGGCTGGC CTGCTTCACT CCCCCAAACT CAAGGAACTC 
ACCAAGGCCC ATGAGCTGGA GGTGAGGCTG CACACTTTCA GCATGTTTGG GATGCCCCGG 
CTGCCCCCTG AGGACCGGCG GCACTGGGAG ATAGGAGAGG GTGGCGACAG TGGCCTGACC 
ATCGAGAAGT CCTGGAGGGA GCTGGTGCCT GGGCACAAGG AGATGAGCCA GGAGCTCTGC 
CACCAACAGG AGGCCCTGTG GGAGCTCCTG ACCACCGAGC TGATCTACGT GAGAAAGCTC 
AAGATCATGA CTGATCTGCT AGCCGCCGGC CTGCTGAACC TGCAGCGAGT GGGACTGCTG 
ATGGAAGTGT CAGCTGAGAC CCTGTTTGGA AATGTCCCCA GCCTGATTCG AACCCACCGG 
AGCTTTTGGG ATGAGGTGCT GGGGCCCACC CTGGAGGAGA CTCGGGCCTC GGGCCAGCCT 
CTGGACCCCA TTGGTCTGCA AAGTGGCTTC CTGACGTTTG GCCAGCGGTT CCACCCCTAT 
GTCCAGTACT GCCTCCGAGT GAAGCAGACC ATGGCTTACG CCCGAGAACA GCAAGAAACT 
AACCCTCTCT TCCATGCCTT CGTGCAGTGG TGTGAGAAGC ACAAGCGCTC TGGGAGGCAG 
ATGCTCTGTG ACTTGCTTAT CAAGCCCCAC CAGCGCATCA CCAAGTACCC ACTGCTGCTC 
CATGCTGTGC TCAAGAGGAG CCCCGAGGCA CGAGCCCAAG AGGCCCTGAA TGCCATGATT 
GAAGCCGTGG AGTCATTCCT GCGACACATC AATGGGCAGG TCCGCCAGGG CGAAGAGCAA 
GAGAGCTTGG CGGCTGCAGC ACAACGCATC GGGCCCTACG AGGTGCTGGA GCCACCCAGT 
GATGAGGTGG AGAAGAACCT GCGCCCATTC TCCACCCTGG ACCTGACGTC CCCCATGCTG 
GGGGTTGCAT CTGAGCACAC CAGACAGCTG CTGCTGGAGG GGCCTGTGCG AGTGAAGGAG 
GGACGAGAAG GGAAGCTGGA CGTGTACCTG TTCCTCTTCT CTGATGTGCT CCTTGTGACC 
AAGCCCCAGC GCAAGGCGGA CAAAGCCAAG GTCATCCGAC CCCCTCTCAT GCTGGAGAAG 
CTCGTGTGCC AACCCCTGCG AGACCCCAAC AGCTTCCTGC TGATCCACCT CACTGAATTC 
CAGTGTGTCT CCAGCGCCCT CCTTGTGCAC TGTCCCAGTC CTACAGACCG TGCCCAGTGG 
CTGGAGAAGA CCCAGCAGGC CCAGGCCGCC CTACAGAAGC TGAAGGCAGA GGAGTATGTT 
CAACAGAAGA GGGAGCTCCT GACCCTCTAT CGGGACCAGG ACAGGGAGTC CCCCAGCACC 
AGGCCCTCCA CGCCTTCCCT GGAGGGCTCT CAGAGCAGCG CAGAGGGGAG GACTCCTGAG 
TTCTCGACCA TTATCCCCCA CCTGGTGGTG ACAGAAGACA CAGATGAAGA TGCTCCCCTT 
GTGCCAGATG ATACCTCAGA CTCTGGCTAC GGCACTTTGA TCCCAGGCAC CCCCACGGGG 
TCCCGCTCCC CACTGAGCCG TCTACGCCAA AGAGCCCTTC GGCGGGACCC TCGCCTCACC 
TTCTCCACCC TGGAACTCCG GGACATCCCT CTGCGTCCCC ACCCTCCCGA CCCCCAAGCT 
CCTCAACGCC GAAGCGCCCC CGAACTGCCG GAAGGAATCC TAAAAGGAGG CAGTCTTCCC 
CAGGAAGACC CACCAACCTG GTCTGAGGAA GAAGATGGGG CCTCCGAGCG AGGGAATGTG 
GTGGTGGAAA CACTCCACAG GGCCCGGCTT CGGGGCCAGC TTCCCTCCTC CCCAACCCAT 
GCTGACTCTG CCGGGGAAAG CCCCTGGGAG TCCTCAGGGG AGGAGGAAGA AGAGGGGCCT 
CTGTTCCTGA AAGCTGGCCA CACATCCCTG CGCCCAATGC GGGCTGAGGA CATGCTCAGA 
GAGATCCGGG AGGAGCTGGC CAGCCAAAGG ATTGAGGGGG CCGAGGAGCC CCGGGACAGC 
AGGCCACGGA AGCTGACTCG GGCCCAGCTG CAGAGGATGC GGGGGCCCCA CATCATTCAG 
CTGGACACCC CTCTGTCCGC ATCAGAGGTA TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005253761.1
CDS	246..2618
Translation	MKAFGPPHEGPLQGLVASRIETYGGRHRASAQSTAGRLYPRGYPVLDPSRRRLQQYVPFARGSGQARGLSPMRLRDPEPEKRHGGHVGAGLLHSPKLKELTKAHELEVRLHTFSMFGMPRLPPEDRRHWEIGEGGDSGLTIEKSWRELVPGHKEMSQELCHQQEALWELLTTELIYVRKLKIMTDLLAAGLLNLQRVGLLMEVSAETLFGNVPSLIRTHRSFWDEVLGPTLEETRASGQPLDPIGLQSGFLTFGQRFHPYVQYCLRVKQTMAYAREQQETNPLFHAFVQWCEKHKRSGRQMLCDLLIKPHQRITKYPLLLHAVLKRSPEARAQEALNAMIEAVESFLRHINGQVRQGEEQESLAAAAQRIGPYEVLEPPSDEVEKNLRPFSTLDLTSPMLGVASEHTRQLLLEGPVRVKEGREGKLDVYLFLFSDVLLVTKPQRKADKAKVIRPPLMLEKLVCQPLRDPNSFLLIHLTEFQCVSSALLVHCPSPTDRAQWLEKTQQAQAALQKLKAEEYVQQKRELLTLYRDQDRESPSTRPSTPSLEGSQSSAEGRTPEFSTIIPHLVVTEDTDEDAPLVPDDTSDSGYGTLIPGTPTGSRSPLSRLRQRALRRDPRLTFSTLELRDIPLRPHPPDPQAPQRRSAPELPEGILKGGSLPQEDPPTWSEEEDGASERGNVVVETLHRARLRGQLPSSPTHADSAGESPWESSGEEEEEGPLFLKAGHTSLRPMRAEDMLREIREELASQRIEGAEEPRDSRPRKLTRAQLQRMRGPHIIQLDTPLSASEV

Target ORF information:

RefSeq Version	XM_005253704.4
Organism	Homo sapiens(human)
Definition	Homo sapiens pleckstrin homology and RhoGEF domain containing G6 (PLEKHG6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005253704.4

ORF Insert Sequence:

ATGAAGGCCT TTGGTCCTCC ACATGAGGGC CCCCTCCAAG GACTCGTGGC CTCCCGCATT 
GAGACTTATG GGGGCCGGCA TCGAGCCTCT GCTCAGAGCA CTGCTGGCAG ACTCTATCCC 
CGAGGATACC CTGTGCTGGA TCCCAGTCGC CGACGCCTCC AGCAGTATGT CCCCTTTGCC 
AGGGGTTCTG GCCAGGCCCG AGGCCTGTCA CCCATGAGAC TGCGAGATCC AGAGCCCGAG 
AAGAGGCACG GGGGCCATGT GGGGGCTGGC CTGCTTCACT CCCCCAAACT CAAGGAACTC 
ACCAAGGCCC ATGAGCTGGA GGTGAGGCTG CACACTTTCA GCATGTTTGG GATGCCCCGG 
CTGCCCCCTG AGGACCGGCG GCACTGGGAG ATAGGAGAGG GTGGCGACAG TGGCCTGACC 
ATCGAGAAGT CCTGGAGGGA GCTGGTGCCT GGGCACAAGG AGATGAGCCA GGAGCTCTGC 
CACCAACAGG AGGCCCTGTG GGAGCTCCTG ACCACCGAGC TGATCTACGT GAGAAAGCTC 
AAGATCATGA CTGATCTGCT AGCCGCCGGC CTGCTGAACC TGCAGCGAGT GGGACTGCTG 
ATGGAAGTGT CAGCTGAGAC CCTGTTTGGA AATGTCCCCA GCCTGATTCG AACCCACCGG 
AGCTTTTGGG ATGAGGTGCT GGGGCCCACC CTGGAGGAGA CTCGGGCCTC GGGCCAGCCT 
CTGGACCCCA TTGGTCTGCA AAGTGGCTTC CTGACGTTTG GCCAGCGGTT CCACCCCTAT 
GTCCAGTACT GCCTCCGAGT GAAGCAGACC ATGGCTTACG CCCGAGAACA GCAAGAAACT 
AACCCTCTCT TCCATGCCTT CGTGCAGTGG TGTGAGAAGC ACAAGCGCTC TGGGAGGCAG 
ATGCTCTGTG ACTTGCTTAT CAAGCCCCAC CAGCGCATCA CCAAGTACCC ACTGCTGCTC 
CATGCTGTGC TCAAGAGGAG CCCCGAGGCA CGAGCCCAAG AGGCCCTGAA TGCCATGATT 
GAAGCCGTGG AGTCATTCCT GCGACACATC AATGGGCAGG TCCGCCAGGG CGAAGAGCAA 
GAGAGCTTGG CGGCTGCAGC ACAACGCATC GGGCCCTACG AGGTGCTGGA GCCACCCAGT 
GATGAGGTGG AGAAGAACCT GCGCCCATTC TCCACCCTGG ACCTGACGTC CCCCATGCTG 
GGGGTTGCAT CTGAGCACAC CAGACAGCTG CTGCTGGAGG GGCCTGTGCG AGTGAAGGAG 
GGACGAGAAG GGAAGCTGGA CGTGTACCTG TTCCTCTTCT CTGATGTGCT CCTTGTGACC 
AAGCCCCAGC GCAAGGCGGA CAAAGCCAAG GTCATCCGAC CCCCTCTCAT GCTGGAGAAG 
CTCGTGTGCC AACCCCTGCG AGACCCCAAC AGCTTCCTGC TGATCCACCT CACTGAATTC 
CAGTGTGTCT CCAGCGCCCT CCTTGTGCAC TGTCCCAGTC CTACAGACCG TGCCCAGTGG 
CTGGAGAAGA CCCAGCAGGC CCAGGCCGCC CTACAGAAGC TGAAGGCAGA GGAGTATGTT 
CAACAGAAGA GGGAGCTCCT GACCCTCTAT CGGGACCAGG ACAGGGAGTC CCCCAGCACC 
AGGCCCTCCA CGCCTTCCCT GGAGGGCTCT CAGAGCAGCG CAGAGGGGAG GACTCCTGAG 
TTCTCGACCA TTATCCCCCA CCTGGTGGTG ACAGAAGACA CAGATGAAGA TGCTCCCCTT 
GTGCCAGATG ATACCTCAGA CTCTGGCTAC GGCACTTTGA TCCCAGGCAC CCCCACGGGG 
TCCCGCTCCC CACTGAGCCG TCTACGCCAA AGAGCCCTTC GGCGGGACCC TCGCCTCACC 
TTCTCCACCC TGGAACTCCG GGACATCCCT CTGCGTCCCC ACCCTCCCGA CCCCCAAGCT 
CCTCAACGCC GAAGCGCCCC CGAACTGCCG GAAGGAATCC TAAAAGGAGG CAGTCTTCCC 
CAGGAAGACC CACCAACCTG GTCTGAGGAA GAAGATGGGG CCTCCGAGCG AGGGAATGTG 
GTGGTGGAAA CACTCCACAG GGCCCGGCTT CGGGGCCAGC TTCCCTCCTC CCCAACCCAT 
GCTGACTCTG CCGGGGAAAG CCCCTGGGAG TCCTCAGGGG AGGAGGAAGA AGAGGGGCCT 
CTGTTCCTGA AAGCTGGCCA CACATCCCTG CGCCCAATGC GGGCTGAGGA CATGCTCAGA 
GAGATCCGGG AGGAGCTGGC CAGCCAAAGG ATTGAGGGGG CCGAGGAGCC CCGGGACAGC 
AGGCCACGGA AGCTGACTCG GGCCCAGCTG CAGAGGATGC GGGGGCCCCA CATCATTCAG 
CTGGACACCC CTCTGTCCGC ATCAGAGGTA TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PLEKHG6 ( XM_006718985.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_006719048.1 Homo sapiens pleckstrin homology and RhoGEF domain containing G6 (PLEKHG6), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu45977
Clone ID Related Accession (Same CDS sequence)	XM_006718985.3
Accession Version	XM_006718985.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2331bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	pleckstrin homology domain-containing family G member 6 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_006718985.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGGCCT TTGGTCCTCC ACATGAGGGC CCCCTCCAAG GACTCGTGGC CTCCCGCATT 
GAGACTTATG GGGGCCGGCA TCGAGCCTCT GCTCAGAGCA CTGCTGGCAG ACTCTATCCC 
CGAGGATACC CTGTGCTGGA TCCCAGTCGC CGACGCCTCC AGCAGTATGT CCCCTTTGCC 
AGGGGTTCTG GCCAGGCCCG AGGCCTGTCA CCCATGAGAC TGCGAGATCC AGAGCCCGAG 
AAGAGGCACG GGGGCCATGT GGGGGCTGGC CTGCTTCACT CCCCCAAACT CAAGGAACTC 
ACCAAGGCCC ATGAGCTGGA GGTGAGGCTG CACACTTTCA GCATGTTTGG GATGCCCCGG 
CTGCCCCCTG AGGACCGGCG GCACTGGGAG ATAGGAGAGG GTGGCGACAG TGGCCTGACC 
ATCGAGAAGT CCTGGAGGGA GCTGGTGCCT GGGCACAAGG AGATGAGCCA GGAGCTCTGC 
CACCAACAGG AGGCCCTGTG GGAGCTCCTG ACCACCGAGC TGATCTACGT GAGAAAGCTC 
AAGATCATGA CTGATCTGCT AGCCGCCGGC CTGCTGAACC TGCAGCGAGT GGGACTGCTG 
ATGGAAGTGT CAGCTGAGAC CCTGTTTGGA AATGTCCCCA GCCTGATTCG AACCCACCGG 
AGCTTTTGGG ATGAGGTGCT GGGGCCCACC CTGGAGGAGA CTCGGGCCTC GGGCCAGCCT 
CTGGACCCCA TTGGTCTGCA AAGTGGCTTC CTGACGTTTG GCCAGCGGTT CCACCCCTAT 
GTCCAGTACT GCCTCCGAGT GAAGCAGACC ATGGCTTACG CCCGAGAACA GCAAGAAACT 
AACCCTCTCT TCCATGCCTT CGTGCAGTGG TGTGAGAAGC ACAAGCGCTC TGGGAGGCAG 
ATGCTCTGTG ACTTGCTTAT CAAGCCCCAC CAGCGCATCA CCAAGTACCC ACTGCTGCTC 
CATGCTGTGC TCAAGAGGAG CCCCGAGGCA CGAGCCCAAG AGGCCCTGAA TGCCATGGTC 
CGCCAGGGCG AAGAGCAAGA GAGCTTGGCG GCTGCAGCAC AACGCATCGG GCCCTACGAG 
GTGCTGGAGC CACCCAGTGA TGAGGTGGAG AAGAACCTGC GCCCATTCTC CACCCTGGAC 
CTGACGTCCC CCATGCTGGG GGTTGCATCT GAGCACACCA GACAGCTGCT GCTGGAGGGG 
CCTGTGCGAG TGAAGGAGGG ACGAGAAGGG AAGCTGGACG TGTACCTGTT CCTCTTCTCT 
GATGTGCTCC TTGTGACCAA GCCCCAGCGC AAGGCGGACA AAGCCAAGGT CATCCGACCC 
CCTCTCATGC TGGAGAAGCT CGTGTGCCAA CCCCTGCGAG ACCCCAACAG CTTCCTGCTG 
ATCCACCTCA CTGAATTCCA GTGTGTCTCC AGCGCCCTCC TTGTGCACTG TCCCAGTCCT 
ACAGACCGTG CCCAGTGGCT GGAGAAGACC CAGCAGGCCC AGGCCGCCCT ACAGAAGCTG 
AAGGCAGAGG AGTATGTTCA ACAGAAGAGG GAGCTCCTGA CCCTCTATCG GGACCAGGAC 
AGGGAGTCCC CCAGCACCAG GCCCTCCACG CCTTCCCTGG AGGGCTCTCA GAGCAGCGCA 
GAGGGGAGGA CTCCTGAGTT CTCGACCATT ATCCCCCACC TGGTGGTGAC AGAAGACACA 
GATGAAGATG CTCCCCTTGT GCCAGATGAT ACCTCAGACT CTGGCTACGG CACTTTGATC 
CCAGGCACCC CCACGGGGTC CCGCTCCCCA CTGAGCCGTC TACGCCAAAG AGCCCTTCGG 
CGGGACCCTC GCCTCACCTT CTCCACCCTG GAACTCCGGG ACATCCCTCT GCGTCCCCAC 
CCTCCCGACC CCCAAGCTCC TCAACGCCGA AGCGCCCCCG AACTGCCGGA AGGAATCCTA 
AAAGGAGGCA GTCTTCCCCA GGAAGACCCA CCAACCTGGT CTGAGGAAGA AGATGGGGCC 
TCCGAGCGAG GGAATGTGGT GGTGGAAACA CTCCACAGGG CCCGGCTTCG GGGCCAGCTT 
CCCTCCTCCC CAACCCATGC TGACTCTGCC GGGGAAAGCC CCTGGGAGTC CTCAGGGGAG 
GAGGAAGAAG AGGGGCCTCT GTTCCTGAAA GCTGGCCACA CATCCCTGCG CCCAATGCGG 
GCTGAGGACA TGCTCAGAGA GATCCGGGAG GAGCTGGCCA GCCAAAGGAT TGAGGGGGCC 
GAGGAGCCCC GGGACAGCAG GCCACGGAAG CTGACTCGGG CCCAGCTGCA GAGGATGCGG 
GGGCCCCACA TCATTCAGCT GGACACCCCT CTGTCCGCAT CAGAGGTATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006719048.1
CDS	246..2576
Translation	MKAFGPPHEGPLQGLVASRIETYGGRHRASAQSTAGRLYPRGYPVLDPSRRRLQQYVPFARGSGQARGLSPMRLRDPEPEKRHGGHVGAGLLHSPKLKELTKAHELEVRLHTFSMFGMPRLPPEDRRHWEIGEGGDSGLTIEKSWRELVPGHKEMSQELCHQQEALWELLTTELIYVRKLKIMTDLLAAGLLNLQRVGLLMEVSAETLFGNVPSLIRTHRSFWDEVLGPTLEETRASGQPLDPIGLQSGFLTFGQRFHPYVQYCLRVKQTMAYAREQQETNPLFHAFVQWCEKHKRSGRQMLCDLLIKPHQRITKYPLLLHAVLKRSPEARAQEALNAMVRQGEEQESLAAAAQRIGPYEVLEPPSDEVEKNLRPFSTLDLTSPMLGVASEHTRQLLLEGPVRVKEGREGKLDVYLFLFSDVLLVTKPQRKADKAKVIRPPLMLEKLVCQPLRDPNSFLLIHLTEFQCVSSALLVHCPSPTDRAQWLEKTQQAQAALQKLKAEEYVQQKRELLTLYRDQDRESPSTRPSTPSLEGSQSSAEGRTPEFSTIIPHLVVTEDTDEDAPLVPDDTSDSGYGTLIPGTPTGSRSPLSRLRQRALRRDPRLTFSTLELRDIPLRPHPPDPQAPQRRSAPELPEGILKGGSLPQEDPPTWSEEEDGASERGNVVVETLHRARLRGQLPSSPTHADSAGESPWESSGEEEEEGPLFLKAGHTSLRPMRAEDMLREIREELASQRIEGAEEPRDSRPRKLTRAQLQRMRGPHIIQLDTPLSASEV

Target ORF information:

RefSeq Version	XM_006718985.3
Organism	Homo sapiens(human)
Definition	Homo sapiens pleckstrin homology and RhoGEF domain containing G6 (PLEKHG6), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006718985.3

ORF Insert Sequence:

ATGAAGGCCT TTGGTCCTCC ACATGAGGGC CCCCTCCAAG GACTCGTGGC CTCCCGCATT 
GAGACTTATG GGGGCCGGCA TCGAGCCTCT GCTCAGAGCA CTGCTGGCAG ACTCTATCCC 
CGAGGATACC CTGTGCTGGA TCCCAGTCGC CGACGCCTCC AGCAGTATGT CCCCTTTGCC 
AGGGGTTCTG GCCAGGCCCG AGGCCTGTCA CCCATGAGAC TGCGAGATCC AGAGCCCGAG 
AAGAGGCACG GGGGCCATGT GGGGGCTGGC CTGCTTCACT CCCCCAAACT CAAGGAACTC 
ACCAAGGCCC ATGAGCTGGA GGTGAGGCTG CACACTTTCA GCATGTTTGG GATGCCCCGG 
CTGCCCCCTG AGGACCGGCG GCACTGGGAG ATAGGAGAGG GTGGCGACAG TGGCCTGACC 
ATCGAGAAGT CCTGGAGGGA GCTGGTGCCT GGGCACAAGG AGATGAGCCA GGAGCTCTGC 
CACCAACAGG AGGCCCTGTG GGAGCTCCTG ACCACCGAGC TGATCTACGT GAGAAAGCTC 
AAGATCATGA CTGATCTGCT AGCCGCCGGC CTGCTGAACC TGCAGCGAGT GGGACTGCTG 
ATGGAAGTGT CAGCTGAGAC CCTGTTTGGA AATGTCCCCA GCCTGATTCG AACCCACCGG 
AGCTTTTGGG ATGAGGTGCT GGGGCCCACC CTGGAGGAGA CTCGGGCCTC GGGCCAGCCT 
CTGGACCCCA TTGGTCTGCA AAGTGGCTTC CTGACGTTTG GCCAGCGGTT CCACCCCTAT 
GTCCAGTACT GCCTCCGAGT GAAGCAGACC ATGGCTTACG CCCGAGAACA GCAAGAAACT 
AACCCTCTCT TCCATGCCTT CGTGCAGTGG TGTGAGAAGC ACAAGCGCTC TGGGAGGCAG 
ATGCTCTGTG ACTTGCTTAT CAAGCCCCAC CAGCGCATCA CCAAGTACCC ACTGCTGCTC 
CATGCTGTGC TCAAGAGGAG CCCCGAGGCA CGAGCCCAAG AGGCCCTGAA TGCCATGGTC 
CGCCAGGGCG AAGAGCAAGA GAGCTTGGCG GCTGCAGCAC AACGCATCGG GCCCTACGAG 
GTGCTGGAGC CACCCAGTGA TGAGGTGGAG AAGAACCTGC GCCCATTCTC CACCCTGGAC 
CTGACGTCCC CCATGCTGGG GGTTGCATCT GAGCACACCA GACAGCTGCT GCTGGAGGGG 
CCTGTGCGAG TGAAGGAGGG ACGAGAAGGG AAGCTGGACG TGTACCTGTT CCTCTTCTCT 
GATGTGCTCC TTGTGACCAA GCCCCAGCGC AAGGCGGACA AAGCCAAGGT CATCCGACCC 
CCTCTCATGC TGGAGAAGCT CGTGTGCCAA CCCCTGCGAG ACCCCAACAG CTTCCTGCTG 
ATCCACCTCA CTGAATTCCA GTGTGTCTCC AGCGCCCTCC TTGTGCACTG TCCCAGTCCT 
ACAGACCGTG CCCAGTGGCT GGAGAAGACC CAGCAGGCCC AGGCCGCCCT ACAGAAGCTG 
AAGGCAGAGG AGTATGTTCA ACAGAAGAGG GAGCTCCTGA CCCTCTATCG GGACCAGGAC 
AGGGAGTCCC CCAGCACCAG GCCCTCCACG CCTTCCCTGG AGGGCTCTCA GAGCAGCGCA 
GAGGGGAGGA CTCCTGAGTT CTCGACCATT ATCCCCCACC TGGTGGTGAC AGAAGACACA 
GATGAAGATG CTCCCCTTGT GCCAGATGAT ACCTCAGACT CTGGCTACGG CACTTTGATC 
CCAGGCACCC CCACGGGGTC CCGCTCCCCA CTGAGCCGTC TACGCCAAAG AGCCCTTCGG 
CGGGACCCTC GCCTCACCTT CTCCACCCTG GAACTCCGGG ACATCCCTCT GCGTCCCCAC 
CCTCCCGACC CCCAAGCTCC TCAACGCCGA AGCGCCCCCG AACTGCCGGA AGGAATCCTA 
AAAGGAGGCA GTCTTCCCCA GGAAGACCCA CCAACCTGGT CTGAGGAAGA AGATGGGGCC 
TCCGAGCGAG GGAATGTGGT GGTGGAAACA CTCCACAGGG CCCGGCTTCG GGGCCAGCTT 
CCCTCCTCCC CAACCCATGC TGACTCTGCC GGGGAAAGCC CCTGGGAGTC CTCAGGGGAG 
GAGGAAGAAG AGGGGCCTCT GTTCCTGAAA GCTGGCCACA CATCCCTGCG CCCAATGCGG 
GCTGAGGACA TGCTCAGAGA GATCCGGGAG GAGCTGGCCA GCCAAAGGAT TGAGGGGGCC 
GAGGAGCCCC GGGACAGCAG GCCACGGAAG CTGACTCGGG CCCAGCTGCA GAGGATGCGG 
GGGCCCCACA TCATTCAGCT GGACACCCCT CTGTCCGCAT CAGAGGTATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PLEKHG6 ( XM_011520967.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011519269.1 Homo sapiens pleckstrin homology and RhoGEF domain containing G6 (PLEKHG6), transcript variant X4, mRNA.

Price & Availability↑

CloneID	OHu69149
Clone ID Related Accession (Same CDS sequence)	XM_011520967.2
Accession Version	XM_011520967.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2307bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	pleckstrin homology domain-containing family G member 6 isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011520967.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGGGCCC CCTCCAAGGA CTCGTGGCCT CCCGCATTGA GACTTATGGG GGCCGGCATC 
GAGCCTCTGC TCAGAGCACT GCTGGCAGAC TCTATCCCCG AGGATACCCT GTGCTGGGGT 
TCTGGCCAGG CCCGAGGCCT GTCACCCATG AGACTGCGAG ATCCAGAGCC CGAGAAGAGG 
CACGGGGGCC ATGTGGGGGC TGGCCTGCTT CACTCCCCCA AACTCAAGGA ACTCACCAAG 
GCCCATGAGC TGGAGGTGAG GCTGCACACT TTCAGCATGT TTGGGATGCC CCGGCTGCCC 
CCTGAGGACC GGCGGCACTG GGAGATAGGA GAGGGTGGCG ACAGTGGCCT GACCATCGAG 
AAGTCCTGGA GGGAGCTGGT GCCTGGGCAC AAGGAGATGA GCCAGGAGCT CTGCCACCAA 
CAGGAGGCCC TGTGGGAGCT CCTGACCACC GAGCTGATCT ACGTGAGAAA GCTCAAGATC 
ATGACTGATC TGCTAGCCGC CGGCCTGCTG AACCTGCAGC GAGTGGGACT GCTGATGGAA 
GTGTCAGCTG AGACCCTGTT TGGAAATGTC CCCAGCCTGA TTCGAACCCA CCGGAGCTTT 
TGGGATGAGG TGCTGGGGCC CACCCTGGAG GAGACTCGGG CCTCGGGCCA GCCTCTGGAC 
CCCATTGGTC TGCAAAGTGG CTTCCTGACG TTTGGCCAGC GGTTCCACCC CTATGTCCAG 
TACTGCCTCC GAGTGAAGCA GACCATGGCT TACGCCCGAG AACAGCAAGA AACTAACCCT 
CTCTTCCATG CCTTCGTGCA GTGGTGTGAG AAGCACAAGC GCTCTGGGAG GCAGATGCTC 
TGTGACTTGC TTATCAAGCC CCACCAGCGC ATCACCAAGT ACCCACTGCT GCTCCATGCT 
GTGCTCAAGA GGAGCCCCGA GGCACGAGCC CAAGAGGCCC TGAATGCCAT GATTGAAGCC 
GTGGAGTCAT TCCTGCGACA CATCAATGGG CAGGTCCGCC AGGGCGAAGA GCAAGAGAGC 
TTGGCGGCTG CAGCACAACG CATCGGGCCC TACGAGGTGC TGGAGCCACC CAGTGATGAG 
GTGGAGAAGA ACCTGCGCCC ATTCTCCACC CTGGACCTGA CGTCCCCCAT GCTGGGGGTT 
GCATCTGAGC ACACCAGACA GCTGCTGCTG GAGGGGCCTG TGCGAGTGAA GGAGGGACGA 
GAAGGGAAGC TGGACGTGTA CCTGTTCCTC TTCTCTGATG TGCTCCTTGT GACCAAGCCC 
CAGCGCAAGG CGGACAAAGC CAAGGTCATC CGACCCCCTC TCATGCTGGA GAAGCTCGTG 
TGCCAACCCC TGCGAGACCC CAACAGCTTC CTGCTGATCC ACCTCACTGA ATTCCAGTGT 
GTCTCCAGCG CCCTCCTTGT GCACTGTCCC AGTCCTACAG ACCGTGCCCA GTGGCTGGAG 
AAGACCCAGC AGGCCCAGGC CGCCCTACAG AAGCTGAAGG CAGAGGAGTA TGTTCAACAG 
AAGAGGGAGC TCCTGACCCT CTATCGGGAC CAGGACAGGG AGTCCCCCAG CACCAGGCCC 
TCCACGCCTT CCCTGGAGGG CTCTCAGAGC AGCGCAGAGG GGAGGACTCC TGAGTTCTCG 
ACCATTATCC CCCACCTGGT GGTGACAGAA GACACAGATG AAGATGCTCC CCTTGTGCCA 
GATGATACCT CAGACTCTGG CTACGGCACT TTGATCCCAG GCACCCCCAC GGGGTCCCGC 
TCCCCACTGA GCCGTCTACG CCAAAGAGCC CTTCGGCGGG ACCCTCGCCT CACCTTCTCC 
ACCCTGGAAC TCCGGGACAT CCCTCTGCGT CCCCACCCTC CCGACCCCCA AGCTCCTCAA 
CGCCGAAGCG CCCCCGAACT GCCGGAAGGA ATCCTAAAAG GAGGCAGTCT TCCCCAGGAA 
GACCCACCAA CCTGGTCTGA GGAAGAAGAT GGGGCCTCCG AGCGAGGGAA TGTGGTGGTG 
GAAACACTCC ACAGGGCCCG GCTTCGGGGC CAGCTTCCCT CCTCCCCAAC CCATGCTGAC 
TCTGCCGGGG AAAGCCCCTG GGAGTCCTCA GGGGAGGAGG AAGAAGAGGG GCCTCTGTTC 
CTGAAAGCTG GCCACACATC CCTGCGCCCA ATGCGGGCTG AGGACATGCT CAGAGAGATC 
CGGGAGGAGC TGGCCAGCCA AAGGATTGAG GGGGCCGAGG AGCCCCGGGA CAGCAGGCCA 
CGGAAGCTGA CTCGGGCCCA GCTGCAGAGG ATGCGGGGGC CCCACATCAT TCAGCTGGAC 
ACCCCTCTGT CCGCATCAGA GGTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011519269.1
CDS	187..2493
Translation	MRAPSKDSWPPALRLMGAGIEPLLRALLADSIPEDTLCWGSGQARGLSPMRLRDPEPEKRHGGHVGAGLLHSPKLKELTKAHELEVRLHTFSMFGMPRLPPEDRRHWEIGEGGDSGLTIEKSWRELVPGHKEMSQELCHQQEALWELLTTELIYVRKLKIMTDLLAAGLLNLQRVGLLMEVSAETLFGNVPSLIRTHRSFWDEVLGPTLEETRASGQPLDPIGLQSGFLTFGQRFHPYVQYCLRVKQTMAYAREQQETNPLFHAFVQWCEKHKRSGRQMLCDLLIKPHQRITKYPLLLHAVLKRSPEARAQEALNAMIEAVESFLRHINGQVRQGEEQESLAAAAQRIGPYEVLEPPSDEVEKNLRPFSTLDLTSPMLGVASEHTRQLLLEGPVRVKEGREGKLDVYLFLFSDVLLVTKPQRKADKAKVIRPPLMLEKLVCQPLRDPNSFLLIHLTEFQCVSSALLVHCPSPTDRAQWLEKTQQAQAALQKLKAEEYVQQKRELLTLYRDQDRESPSTRPSTPSLEGSQSSAEGRTPEFSTIIPHLVVTEDTDEDAPLVPDDTSDSGYGTLIPGTPTGSRSPLSRLRQRALRRDPRLTFSTLELRDIPLRPHPPDPQAPQRRSAPELPEGILKGGSLPQEDPPTWSEEEDGASERGNVVVETLHRARLRGQLPSSPTHADSAGESPWESSGEEEEEGPLFLKAGHTSLRPMRAEDMLREIREELASQRIEGAEEPRDSRPRKLTRAQLQRMRGPHIIQLDTPLSASEV

Target ORF information:

RefSeq Version	XM_011520967.2
Organism	Homo sapiens(human)
Definition	Homo sapiens pleckstrin homology and RhoGEF domain containing G6 (PLEKHG6), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011520967.2

ORF Insert Sequence:

ATGAGGGCCC CCTCCAAGGA CTCGTGGCCT CCCGCATTGA GACTTATGGG GGCCGGCATC 
GAGCCTCTGC TCAGAGCACT GCTGGCAGAC TCTATCCCCG AGGATACCCT GTGCTGGGGT 
TCTGGCCAGG CCCGAGGCCT GTCACCCATG AGACTGCGAG ATCCAGAGCC CGAGAAGAGG 
CACGGGGGCC ATGTGGGGGC TGGCCTGCTT CACTCCCCCA AACTCAAGGA ACTCACCAAG 
GCCCATGAGC TGGAGGTGAG GCTGCACACT TTCAGCATGT TTGGGATGCC CCGGCTGCCC 
CCTGAGGACC GGCGGCACTG GGAGATAGGA GAGGGTGGCG ACAGTGGCCT GACCATCGAG 
AAGTCCTGGA GGGAGCTGGT GCCTGGGCAC AAGGAGATGA GCCAGGAGCT CTGCCACCAA 
CAGGAGGCCC TGTGGGAGCT CCTGACCACC GAGCTGATCT ACGTGAGAAA GCTCAAGATC 
ATGACTGATC TGCTAGCCGC CGGCCTGCTG AACCTGCAGC GAGTGGGACT GCTGATGGAA 
GTGTCAGCTG AGACCCTGTT TGGAAATGTC CCCAGCCTGA TTCGAACCCA CCGGAGCTTT 
TGGGATGAGG TGCTGGGGCC CACCCTGGAG GAGACTCGGG CCTCGGGCCA GCCTCTGGAC 
CCCATTGGTC TGCAAAGTGG CTTCCTGACG TTTGGCCAGC GGTTCCACCC CTATGTCCAG 
TACTGCCTCC GAGTGAAGCA GACCATGGCT TACGCCCGAG AACAGCAAGA AACTAACCCT 
CTCTTCCATG CCTTCGTGCA GTGGTGTGAG AAGCACAAGC GCTCTGGGAG GCAGATGCTC 
TGTGACTTGC TTATCAAGCC CCACCAGCGC ATCACCAAGT ACCCACTGCT GCTCCATGCT 
GTGCTCAAGA GGAGCCCCGA GGCACGAGCC CAAGAGGCCC TGAATGCCAT GATTGAAGCC 
GTGGAGTCAT TCCTGCGACA CATCAATGGG CAGGTCCGCC AGGGCGAAGA GCAAGAGAGC 
TTGGCGGCTG CAGCACAACG CATCGGGCCC TACGAGGTGC TGGAGCCACC CAGTGATGAG 
GTGGAGAAGA ACCTGCGCCC ATTCTCCACC CTGGACCTGA CGTCCCCCAT GCTGGGGGTT 
GCATCTGAGC ACACCAGACA GCTGCTGCTG GAGGGGCCTG TGCGAGTGAA GGAGGGACGA 
GAAGGGAAGC TGGACGTGTA CCTGTTCCTC TTCTCTGATG TGCTCCTTGT GACCAAGCCC 
CAGCGCAAGG CGGACAAAGC CAAGGTCATC CGACCCCCTC TCATGCTGGA GAAGCTCGTG 
TGCCAACCCC TGCGAGACCC CAACAGCTTC CTGCTGATCC ACCTCACTGA ATTCCAGTGT 
GTCTCCAGCG CCCTCCTTGT GCACTGTCCC AGTCCTACAG ACCGTGCCCA GTGGCTGGAG 
AAGACCCAGC AGGCCCAGGC CGCCCTACAG AAGCTGAAGG CAGAGGAGTA TGTTCAACAG 
AAGAGGGAGC TCCTGACCCT CTATCGGGAC CAGGACAGGG AGTCCCCCAG CACCAGGCCC 
TCCACGCCTT CCCTGGAGGG CTCTCAGAGC AGCGCAGAGG GGAGGACTCC TGAGTTCTCG 
ACCATTATCC CCCACCTGGT GGTGACAGAA GACACAGATG AAGATGCTCC CCTTGTGCCA 
GATGATACCT CAGACTCTGG CTACGGCACT TTGATCCCAG GCACCCCCAC GGGGTCCCGC 
TCCCCACTGA GCCGTCTACG CCAAAGAGCC CTTCGGCGGG ACCCTCGCCT CACCTTCTCC 
ACCCTGGAAC TCCGGGACAT CCCTCTGCGT CCCCACCCTC CCGACCCCCA AGCTCCTCAA 
CGCCGAAGCG CCCCCGAACT GCCGGAAGGA ATCCTAAAAG GAGGCAGTCT TCCCCAGGAA 
GACCCACCAA CCTGGTCTGA GGAAGAAGAT GGGGCCTCCG AGCGAGGGAA TGTGGTGGTG 
GAAACACTCC ACAGGGCCCG GCTTCGGGGC CAGCTTCCCT CCTCCCCAAC CCATGCTGAC 
TCTGCCGGGG AAAGCCCCTG GGAGTCCTCA GGGGAGGAGG AAGAAGAGGG GCCTCTGTTC 
CTGAAAGCTG GCCACACATC CCTGCGCCCA ATGCGGGCTG AGGACATGCT CAGAGAGATC 
CGGGAGGAGC TGGCCAGCCA AAGGATTGAG GGGGCCGAGG AGCCCCGGGA CAGCAGGCCA 
CGGAAGCTGA CTCGGGCCCA GCTGCAGAGG ATGCGGGGGC CCCACATCAT TCAGCTGGAC 
ACCCCTCTGT CCGCATCAGA GGTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PLEKHG6 ( XM_017019555.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016875044.1 Homo sapiens pleckstrin homology and RhoGEF domain containing G6 (PLEKHG6), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu83931
Clone ID Related Accession (Same CDS sequence)	XM_017019555.1
Accession Version	XM_017019555.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2367bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	pleckstrin homology domain-containing family G member 6 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGGCCT TTGGTCCTCC ACATGAGGGC CCCCTCCAAG GACTCGTGGC CTCCCGCATT 
GAGACTTATG GGGGCCGGCA TCGAGCCTCT GCTCAGAGCA CTGCTGGCAG ACTCTATCCC 
CGAGGATACC CTGTGCTGGA TCCCAGTCGC CGACGCCTCC AGCAGTATGT CCCCTTTGCC 
AGGGGTTCTG GCCAGGCCCG AGGCCTGTCA CCCATGAGAC TGCGAGATCC AGAGCCCGAG 
AAGAGGCACG GGGGCCATGT GGGGGCTGGC CTGCTTCACT CCCCCAAACT CAAGGAACTC 
ACCAAGGCCC ATGAGCTGGA GGTGAGGCTG CACACTTTCA GCATGTTTGG GATGCCCCGG 
CTGCCCCCTG AGGACCGGCG GCACTGGGAG ATAGGAGAGG GTGGCGACAG TGGCCTGACC 
ATCGAGAAGT CCTGGAGGGA GCTGGTGCCT GGGCACAAGG AGATGAGCCA GGAGCTCTGC 
CACCAACAGG AGGCCCTGTG GGAGCTCCTG ACCACCGAGC TGATCTACGT GAGAAAGCTC 
AAGATCATGA CTGATCTGCT AGCCGCCGGC CTGCTGAACC TGCAGCGAGT GGGACTGCTG 
ATGGAAGTGT CAGCTGAGAC CCTGTTTGGA AATGTCCCCA GCCTGATTCG AACCCACCGG 
AGCTTTTGGG ATGAGGTGCT GGGGCCCACC CTGGAGGAGA CTCGGGCCTC GGGCCAGCCT 
CTGGACCCCA TTGGTCTGCA AAGTGGCTTC CTGACGTTTG GCCAGCGGTT CCACCCCTAT 
GTCCAGTACT GCCTCCGAGT GAAGCAGACC ATGGCTTACG CCCGAGAACA GCAAGAAACT 
AACCCTCTCT TCCATGCCTT CGTGCAGTGG TGTGAGAAGC ACAAGCGCTC TGGGAGGCAG 
ATGCTCTGTG ACTTGCTTAT CAAGCCCCAC CAGCGCATCA CCAAGTACCC ACTGCTGCTC 
CATGCTGTGC TCAAGAGGAG CCCCGAGGCA CGAGCCCAAG AGGCCCTGAA TGCCATGATT 
GAAGCCGTGG AGTCATTCCT GCGACACATC AATGGGCAGG TCCGCCAGGG CGAAGAGCAA 
GAGAGCTTGG CGGCTGCAGC ACAACGCATC GGGCCCTACG AGGTGCTGGA GCCACCCAGT 
GATGAGGTGG AGAAGAACCT GCGCCCATTC TCCACCCTGG ACCTGACGTC CCCCATGCTG 
GGGGTTGCAT CTGAGCACAC CAGACAGCTG CTGCTGGAGG GGCCTGTGCG AGTGAAGGAG 
GGACGAGAAG GGAAGCTGGA CGTGTACCTG TTCCTCTTCT CTGATGTGCT CCTTGTGACC 
AAGCCCCAGC GCAAGGCGGA CAAAGCCAAG GTCATCCGAC CCCCTCTCAT GCTGGAGAAG 
CTCGTGTGCC AACCCCTGCG AGACCCCAAC AGCTTCCTGC TGATCCACCT CACTGAATTC 
CAGTGTGTCT CCAGCGCCCT CCTTGTGCAC TGTCCCAGTC CTACAGACCG TGCCCAGTGG 
CTGGAGAAGA CCCAGCAGGC CCAGGCCGCC CTACAGAAGC TGAAGGCAGA GGAGTATGTT 
CAACAGAAGA GGGAGCTCCT GACCCTCTAT CGGGACCAGG ACAGGGAGTC CCCCAGCACC 
AGGCCCTCCA CGCCTTCCCT GGAGGGCTCT CAGAGCAGCG CAGAGGGGAG GACTCCTGAG 
TTCTCGACCA TTATCCCCCA CCTGGTGGTG ACAGAAGACA CAGATGAAGA TGCTCCCCTT 
GTGCCAGATG ATACCTCAGA CTCTGGCTAC GGCACTTTGA TCCCAGGCAC CCCCACGGGG 
TCCCGCTCCC CACTGAGCCG TCTACGCCAA AGAGCCCTTC GGCGGGACCC TCGCCTCACC 
TTCTCCACCC TGGAACTCCG GGACATCCCT CTGCGTCCCC ACCCTCCCGA CCCCCAAGCT 
CCTCAACGCC GAAGCGCCCC CGAACTGCCG GAAGGAATCC TAAAAGGAGG CAGTCTTCCC 
CAGGAAGACC CACCAACCTG GTCTGAGGAA GAAGATGGGG CCTCCGAGCG AGGGAATGTG 
GTGGTGGAAA CACTCCACAG GGCCCGGCTT CGGGGCCAGC TTCCCTCCTC CCCAACCCAT 
GCTGACTCTG CCGGGGAAAG CCCCTGGGAG TCCTCAGGGG AGGAGGAAGA AGAGGGGCCT 
CTGTTCCTGA AAGCTGGCCA CACATCCCTG CGCCCAATGC GGGCTGAGGA CATGCTCAGA 
GAGATCCGGG AGGAGCTGGC CAGCCAAAGG ATTGAGGGGG CCGAGGAGCC CCGGGACAGC 
AGGCCACGGA AGCTGACTCG GGCCCAGCTG CAGAGGATGC GGGGGCCCCA CATCATTCAG 
CTGGACACCC CTCTGTCCGC ATCGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016875044.1
CDS	246..2612
Translation	MKAFGPPHEGPLQGLVASRIETYGGRHRASAQSTAGRLYPRGYPVLDPSRRRLQQYVPFARGSGQARGLSPMRLRDPEPEKRHGGHVGAGLLHSPKLKELTKAHELEVRLHTFSMFGMPRLPPEDRRHWEIGEGGDSGLTIEKSWRELVPGHKEMSQELCHQQEALWELLTTELIYVRKLKIMTDLLAAGLLNLQRVGLLMEVSAETLFGNVPSLIRTHRSFWDEVLGPTLEETRASGQPLDPIGLQSGFLTFGQRFHPYVQYCLRVKQTMAYAREQQETNPLFHAFVQWCEKHKRSGRQMLCDLLIKPHQRITKYPLLLHAVLKRSPEARAQEALNAMIEAVESFLRHINGQVRQGEEQESLAAAAQRIGPYEVLEPPSDEVEKNLRPFSTLDLTSPMLGVASEHTRQLLLEGPVRVKEGREGKLDVYLFLFSDVLLVTKPQRKADKAKVIRPPLMLEKLVCQPLRDPNSFLLIHLTEFQCVSSALLVHCPSPTDRAQWLEKTQQAQAALQKLKAEEYVQQKRELLTLYRDQDRESPSTRPSTPSLEGSQSSAEGRTPEFSTIIPHLVVTEDTDEDAPLVPDDTSDSGYGTLIPGTPTGSRSPLSRLRQRALRRDPRLTFSTLELRDIPLRPHPPDPQAPQRRSAPELPEGILKGGSLPQEDPPTWSEEEDGASERGNVVVETLHRARLRGQLPSSPTHADSAGESPWESSGEEEEEGPLFLKAGHTSLRPMRAEDMLREIREELASQRIEGAEEPRDSRPRKLTRAQLQRMRGPHIIQLDTPLSAS

Target ORF information:

RefSeq Version	XM_017019555.1
Organism	Homo sapiens(human)
Definition	Homo sapiens pleckstrin homology and RhoGEF domain containing G6 (PLEKHG6), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017019555.1

ORF Insert Sequence:

ATGAAGGCCT TTGGTCCTCC ACATGAGGGC CCCCTCCAAG GACTCGTGGC CTCCCGCATT 
GAGACTTATG GGGGCCGGCA TCGAGCCTCT GCTCAGAGCA CTGCTGGCAG ACTCTATCCC 
CGAGGATACC CTGTGCTGGA TCCCAGTCGC CGACGCCTCC AGCAGTATGT CCCCTTTGCC 
AGGGGTTCTG GCCAGGCCCG AGGCCTGTCA CCCATGAGAC TGCGAGATCC AGAGCCCGAG 
AAGAGGCACG GGGGCCATGT GGGGGCTGGC CTGCTTCACT CCCCCAAACT CAAGGAACTC 
ACCAAGGCCC ATGAGCTGGA GGTGAGGCTG CACACTTTCA GCATGTTTGG GATGCCCCGG 
CTGCCCCCTG AGGACCGGCG GCACTGGGAG ATAGGAGAGG GTGGCGACAG TGGCCTGACC 
ATCGAGAAGT CCTGGAGGGA GCTGGTGCCT GGGCACAAGG AGATGAGCCA GGAGCTCTGC 
CACCAACAGG AGGCCCTGTG GGAGCTCCTG ACCACCGAGC TGATCTACGT GAGAAAGCTC 
AAGATCATGA CTGATCTGCT AGCCGCCGGC CTGCTGAACC TGCAGCGAGT GGGACTGCTG 
ATGGAAGTGT CAGCTGAGAC CCTGTTTGGA AATGTCCCCA GCCTGATTCG AACCCACCGG 
AGCTTTTGGG ATGAGGTGCT GGGGCCCACC CTGGAGGAGA CTCGGGCCTC GGGCCAGCCT 
CTGGACCCCA TTGGTCTGCA AAGTGGCTTC CTGACGTTTG GCCAGCGGTT CCACCCCTAT 
GTCCAGTACT GCCTCCGAGT GAAGCAGACC ATGGCTTACG CCCGAGAACA GCAAGAAACT 
AACCCTCTCT TCCATGCCTT CGTGCAGTGG TGTGAGAAGC ACAAGCGCTC TGGGAGGCAG 
ATGCTCTGTG ACTTGCTTAT CAAGCCCCAC CAGCGCATCA CCAAGTACCC ACTGCTGCTC 
CATGCTGTGC TCAAGAGGAG CCCCGAGGCA CGAGCCCAAG AGGCCCTGAA TGCCATGATT 
GAAGCCGTGG AGTCATTCCT GCGACACATC AATGGGCAGG TCCGCCAGGG CGAAGAGCAA 
GAGAGCTTGG CGGCTGCAGC ACAACGCATC GGGCCCTACG AGGTGCTGGA GCCACCCAGT 
GATGAGGTGG AGAAGAACCT GCGCCCATTC TCCACCCTGG ACCTGACGTC CCCCATGCTG 
GGGGTTGCAT CTGAGCACAC CAGACAGCTG CTGCTGGAGG GGCCTGTGCG AGTGAAGGAG 
GGACGAGAAG GGAAGCTGGA CGTGTACCTG TTCCTCTTCT CTGATGTGCT CCTTGTGACC 
AAGCCCCAGC GCAAGGCGGA CAAAGCCAAG GTCATCCGAC CCCCTCTCAT GCTGGAGAAG 
CTCGTGTGCC AACCCCTGCG AGACCCCAAC AGCTTCCTGC TGATCCACCT CACTGAATTC 
CAGTGTGTCT CCAGCGCCCT CCTTGTGCAC TGTCCCAGTC CTACAGACCG TGCCCAGTGG 
CTGGAGAAGA CCCAGCAGGC CCAGGCCGCC CTACAGAAGC TGAAGGCAGA GGAGTATGTT 
CAACAGAAGA GGGAGCTCCT GACCCTCTAT CGGGACCAGG ACAGGGAGTC CCCCAGCACC 
AGGCCCTCCA CGCCTTCCCT GGAGGGCTCT CAGAGCAGCG CAGAGGGGAG GACTCCTGAG 
TTCTCGACCA TTATCCCCCA CCTGGTGGTG ACAGAAGACA CAGATGAAGA TGCTCCCCTT 
GTGCCAGATG ATACCTCAGA CTCTGGCTAC GGCACTTTGA TCCCAGGCAC CCCCACGGGG 
TCCCGCTCCC CACTGAGCCG TCTACGCCAA AGAGCCCTTC GGCGGGACCC TCGCCTCACC 
TTCTCCACCC TGGAACTCCG GGACATCCCT CTGCGTCCCC ACCCTCCCGA CCCCCAAGCT 
CCTCAACGCC GAAGCGCCCC CGAACTGCCG GAAGGAATCC TAAAAGGAGG CAGTCTTCCC 
CAGGAAGACC CACCAACCTG GTCTGAGGAA GAAGATGGGG CCTCCGAGCG AGGGAATGTG 
GTGGTGGAAA CACTCCACAG GGCCCGGCTT CGGGGCCAGC TTCCCTCCTC CCCAACCCAT 
GCTGACTCTG CCGGGGAAAG CCCCTGGGAG TCCTCAGGGG AGGAGGAAGA AGAGGGGCCT 
CTGTTCCTGA AAGCTGGCCA CACATCCCTG CGCCCAATGC GGGCTGAGGA CATGCTCAGA 
GAGATCCGGG AGGAGCTGGC CAGCCAAAGG ATTGAGGGGG CCGAGGAGCC CCGGGACAGC 
AGGCCACGGA AGCTGACTCG GGCCCAGCTG CAGAGGATGC GGGGGCCCCA CATCATTCAG 
CTGGACACCC CTCTGTCCGC ATCGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Myosin II-interacting guanine nucleotide exchange factor (MYOGEF) promotes bleb retraction via stimulating cortex reassembly at the bleb membrane.
Molecular biology of the cell(2018 Jan)
Jiao M,Wu D,Wei Q

Intramolecular interactions between the Dbl homology (DH) domain and the carboxyl-terminal region of myosin II-interacting guanine nucleotide exchange factor (MyoGEF) act as an autoinhibitory mechanism for the regulation of MyoGEF functions.
The Journal of biological chemistry289(49)34033-48(2014 Dec)
Wu D,Jiao M,Zu S,Sollecito CC,Jimenez-Cowell K,Mold AJ,Kennedy RM,Wei Q

Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk.
Nature genetics46(6)533-42(2014 Jun)
Zhang B,Jia WH,Matsuda K,Kweon SS,Matsuo K,Xiang YB,Shin A,Jee SH,Kim DH,Cai Q,Long J,Shi J,Wen W,Yang G,Zhang Y,Li C,Li B,Guo Y,Ren Z,Ji BT,Pan ZZ,Takahashi A,Shin MH,Matsuda F,Gao YT,Oh JH,Kim S,Ahn YO,,Chan AT,Chang-Claude J,Slattery ML,,Gruber SB,Schumacher FR,Stenzel SL,,Casey G,Kim HR,Jeong JY,Park JW,Li HL,Hosono S,Cho SH,Kubo M,Shu XO,Zeng YX,Zheng W

Phosphorylation of myosin II-interacting guanine nucleotide exchange factor (MyoGEF) at threonine 544 by aurora B kinase promotes the binding of polo-like kinase 1 to MyoGEF.
The Journal of biological chemistry289(10)7142-50(2014 Mar)
Wu D,Asiedu M,Matsumura F,Wei Q

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PLEKHG6 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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