Gene Symbol | PPP1R8 |
Entrez Gene ID | 5511 |
Full Name | protein phosphatase 1 regulatory subunit 8 |
Synonyms | ARD-1,ARD1,NIPP-1,NIPP1,PRO2047 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA. [provided by RefSeq, Jul 2008]. |
Disorder MIM: |