AGGF1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	AGGF1
Entrez Gene ID	55109
Full Name	angiogenic factor with G-patch and FHA domains 1
Synonyms	GPATC7,GPATCH7,HSU84971,HUS84971,VG5Q
General protein information	Preferred Names angiogenic factor with G-patch and FHA domains 1 Names angiogenic factor with G patch and FHA domains 1 G patch domain-containing protein 7 angiogenic factor VG5Q vasculogenesis gene on 5q protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 5 Map Location: 5q13.3
Summary	This gene encodes an angiogenic factor that promotes proliferation of endothelial cells. Mutations in this gene are associated with a susceptibility to Klippel-Trenaunay syndrome. Pseudogenes of this gene are found on chromosomes 3, 4, 10 and 16.[provided by RefSeq, Sep 2010].
Disorder MIM:	608464

mRNA and Protein(s)

mRNA	Protein	Name
NM_018046.4	NP_060516.2	angiogenic factor with G patch and FHA domains 1
NM_018046.5	NP_060516.2	angiogenic factor with G patch and FHA domains 1

Pathways from BioSystems

Homologies

Xenopus tropicalis (tropical clawed frog)	aggf1	XP_002940925.2
Canis lupus familiaris (dog)	AGGF1	XP_005618241.1
Gallus gallus (chicken)	AGGF1	XP_414679.3
Homo sapiens (human)	AGGF1	NP_060516.2
	AGGF1	XP_001106588.1
Mus musculus (house mouse)	Aggf1	NP_079906.2
Rattus norvegicus (Norway rat)	Aggf1	XP_006231882.1
Pan troglodytes (chimpanzee)	AGGF1	XP_526886.1
Bos taurus (cattle)	AGGF1	NP_001069000.2

Gene Ontology
Bibliography

Related articles in PubMed

Angiogenic Factor With G Patch and FHA Domains 1 Is a Novel Regulator of Vascular Injury.
Zhou B, Zeng S, Li N, Yu L, Yang G, Yang Y, Zhang X, Fang M, Xia J, Xu Y
Arteriosclerosis, thrombosis, and vascular biology37(4)675-684(2017 Apr)

High Expression of Angiogenic Factor with G-Patch and FHA Domain1 (AGGF1) Predicts Poor Prognosis in Gastric Cancer.
Yao HH, Wang BJ, Wu Y, Huang Q
Medical science monitor : international medical journal of experimental and clinical research231286-1294(2017 Mar)

Polymorphic Variants rs13155212 (T/C) and rs7704267 (G/C) in the AGGF1 Gene and Risk of Varicose Veins of the Lower Extremities in the Population of Ethnic Russians.
Shadrina AS, Smetanina MA, Sevost'ianova KS, Sokolova EA, Shevela AI, Selivestrov EI, Demekhova MY, Shonov OA, Ilyukhin EA, Voronina EN, Zolotukhin IA, Kirienko AI, Filipenko ML
Bulletin of experimental biology and medicine161(5)698-702(2016 Sep)

Overexpression of AGGF1 is correlated with angiogenesis and poor prognosis of hepatocellular carcinoma.
Wang W, Li GY, Zhu JY, Huang DB, Zhou HC, Zhong W, Ji CS
Medical oncology (Northwood, London, England)32(4)131(2015 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Aggf1 has a role in regulating vascular injury.
Title: Angiogenic Factor With G Patch and FHA Domains 1 Is a Novel Regulator of Vascular Injury.

High expression of AGGF1 predicts poor prognosis in gastric cancer patients.
Title: High Expression of Angiogenic Factor with G-Patch and FHA Domain1 (AGGF1) Predicts Poor Prognosis in Gastric Cancer.

AGGF1 gene polymorphism does not affect the risk of varicose veins of the legs in ethnic Russians.
Title: Polymorphic Variants rs13155212 (T/C) and rs7704267 (G/C) in the AGGF1 Gene and Risk of Varicose Veins of the Lower Extremities in the Population of Ethnic Russians.

Overexpression of AGGF1 is correlated with angiogenesis in hepatocellular carcinoma.
Title: Overexpression of AGGF1 is correlated with angiogenesis and poor prognosis of hepatocellular carcinoma.

AGGF1 reduces myocardial apoptosis and inflammation and enhances angiogenesis, leading to decreased infarct size after I/R injury.
Title: AGGF1 protects from myocardial ischemia/reperfusion injury by regulating myocardial apoptosis and angiogenesis.

The following AGGF1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the AGGF1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu23381	NM_018046.5 Latest version!	Homo sapiens angiogenic factor with G-patch and FHA domains 1 (AGGF1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00
View Old Accession Versions >>
OHu23381	NM_018046.4	Homo sapiens angiogenic factor with G-patch and FHA domains 1 (AGGF1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$391.30 $559.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

AGGF1 ( NM_018046.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_060516.2 Homo sapiens angiogenic factor with G-patch and FHA domains 1 (AGGF1), mRNA.

Price & Availability↑

CloneID	OHu23381
Clone ID Related Accession (Same CDS sequence)	NM_018046.4 , NM_018046.5
Accession Version	NM_018046.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2145bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	angiogenic factor with G patch and FHA domains 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC008581.11, BI561566.1, AY500994.1, DR157679.1, BX648120.1 and AI453097.1. This sequence is a reference standard in the RefSeqGene project. On Sep 16, 2010 this sequence version replaced NM_018046.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.183314.1, SRR1803611.58040.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCTCGG AGGCGCCGTC CCCGCCGCGG TCGCCGCCGC CGCCCACCTC CCCCGAGCCT 
GAGCTGGCCC AGCTAAGGCG GAAGGTGGAG AAGTTGGAAC GTGAACTGCG GAGCTGCAAG 
CGGCAGGTGC GGGAGATCGA GAAGCTGCTG CATCACACAG AACGGCTGTA CCAGAACGCA 
GAAAGCAACA ACCAGGAGCT CCGCACGCAG GTGGAAGAAC TCAGTAAAAT ACTCCAACGT 
GGGAGAAATG AAGATAATAA AAAGTCTGAT GTAGAAGTAC AAACAGAGAA CCATGCTCCT 
TGGTCAATCT CAGATTATTT TTATCAGACG TACTACAATG ACGTTAGTCT TCCAAATAAA 
GTGACTGAAC TGTCAGATCA ACAAGATCAA GCTATCGAAA CTTCTATTTT GAATTCTAAA 
GACCATTTAC AAGTAGAAAA TGATGCTTAC CCTGGTACCG ATAGAACAGA AAATGTTAAA 
TATAGACAAG TGGACCATTT TGCCTCAAAT TCACAGGAGC CAGCATCTGC ATTAGCAACA 
GAAGATACCT CCTTAGAAGG CTCATCATTA GCTGAAAGTT TGAGAGCTGC AGCAGAAGCG 
GCTGTATCAC AGACTGGATT TAGTTATGAT GAAAATACTG GACTGTATTT TGACCACAGC 
ACTGGTTTCT ATTATGATTC TGAAAATCAA CTCTATTATG ATCCTTCCAC TGGAATTTAT 
TACTATTGTG ATGTGGAAAG TGGTCGTTAT CAGTTTCATT CTCGAGTAGA TTTGCAACCT 
TATCCGACTT CTAGCACAAA ACAAAGTAAA GATAAAAAAT TGAAGAAGAA AAGAAAAGAT 
CCAGATTCTT CTGCAACAAA TGAGGAAAAG GATTTGAACT CAGAGGATCA AAAAGCCTTC 
AGTGTTGAAC ATACAAGCTG CAATGAGGAA GAAAATTTCG CAAATATGAA AAAGAAGGCC 
AAAATAGGCA TTCATCACAA AAATAGTCCC CCCAAAGTCA CTGTTCCAAC TAGTGGAAAT 
ACTATAGAGT CTCCTCTTCA TGAAAACATC TCTAATTCAA CATCATTTAA AGATGAGAAA 
ATCATGGAGA CTGATAGTGA ACCAGAGGAA GGTGAAATTA CAGACTCTCA GACTGAGGAT 
AGTTATGACG AAGCCATTAC CAGTGAAGGC AATGTAACTG CAGAAGATAG TGAGGATGAA 
GATGAAGACA AAATTTGGCC CCCATGTATT AGAGTAATTG TCATTAGATC ACCTGTGTTG 
CAGATAGGAT CACTCTTTAT CATTACTGCT GTAAACCCTG CTACAATTGG AAGAGAAAAG 
GATATGGAAC ATACTCTCCG AATCCCTGAA GTTGGTGTCA GTAAGTTTCA TGCAGAAATT 
TATTTTGACC ATGACTTACA AAGTTATGTC CTTGTGGATC AAGGCAGTCA AAATGGCACA 
ATTGTTAATG GAAAACAGAT TCTTCAGCCG AAAACTAAAT GTGACCCTTA CGTACTTGAG 
CATGGAGATG AAGTCAAAAT TGGAGAAACT GTCTTATCCT TTCACATTCA TCCTGGCAGT 
GATACCTGTG ATGGCTGTGA ACCAGGGCAG GTTAGAGCCC ACCTTCGCCT TGATAAGAAA 
GATGAATCTT TTGTTGGTCC AACACTAAGT AAGGAGGAAA AAGAGTTGGA AAGAAGAAAA 
GAATTAAAGA AAATACGAGT AAAATATGGT TTACAGAATA CAGAATACGA AGATGAAAAG 
ACATTGAAGA ATCCAAAATA TAAAGATAGA GCTGGAAAAC GTAGGGAGCA GGTTGGAAGT 
GAAGGAACTT TCCAAAGAGA TGATGCTCCT GCATCTGTTC ATTCTGAAAT TACTGATAGC 
AACAAAGGTC GGAAGATGTT GGAGAAGATG GGTTGGAAGA AAGGAGAGGG CCTGGGGAAG 
GATGGTGGAG GAATGAAAAC GCCGATCCAG CTTCAGCTTC GGCGAACACA TGCAGGCTTG 
GGGACAGGCA AACCATCCTC ATTTGAAGAT GTTCACCTTC TCCAAAACAA GAACAAAAAA 
AACTGGGACA AAGCACGAGA GCGGTTTACT GAAAACTTCC CAGAAACTAA GCCTCAAAAA 
GATGACCCAG GGACCATGCC TTGGGTAAAA GGGACTTTAG AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060516.2
CDS	383..2527
Translation	MASEAPSPPRSPPPPTSPEPELAQLRRKVEKLERELRSCKRQVREIEKLLHHTERLYQNAESNNQELRTQVEELSKILQRGRNEDNKKSDVEVQTENHAPWSISDYFYQTYYNDVSLPNKVTELSDQQDQAIETSILNSKDHLQVENDAYPGTDRTENVKYRQVDHFASNSQEPASALATEDTSLEGSSLAESLRAAAEAAVSQTGFSYDENTGLYFDHSTGFYYDSENQLYYDPSTGIYYYCDVESGRYQFHSRVDLQPYPTSSTKQSKDKKLKKKRKDPDSSATNEEKDLNSEDQKAFSVEHTSCNEEENFANMKKKAKIGIHHKNSPPKVTVPTSGNTIESPLHENISNSTSFKDEKIMETDSEPEEGEITDSQTEDSYDEAITSEGNVTAEDSEDEDEDKIWPPCIRVIVIRSPVLQIGSLFIITAVNPATIGREKDMEHTLRIPEVGVSKFHAEIYFDHDLQSYVLVDQGSQNGTIVNGKQILQPKTKCDPYVLEHGDEVKIGETVLSFHIHPGSDTCDGCEPGQVRAHLRLDKKDESFVGPTLSKEEKELERRKELKKIRVKYGLQNTEYEDEKTLKNPKYKDRAGKRREQVGSEGTFQRDDAPASVHSEITDSNKGRKMLEKMGWKKGEGLGKDGGGMKTPIQLQLRRTHAGLGTGKPSSFEDVHLLQNKNKKNWDKARERFTENFPETKPQKDDPGTMPWVKGTLE

Target ORF information:

RefSeq Version	NM_018046.4
Organism	Homo sapiens(human)
Definition	Homo sapiens angiogenic factor with G-patch and FHA domains 1 (AGGF1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018046.4

ORF Insert Sequence:

ATGGCCTCGG AGGCGCCGTC CCCGCCGCGG TCGCCGCCGC CGCCCACCTC CCCCGAGCCT 
GAGCTGGCCC AGCTAAGGCG GAAGGTGGAG AAGTTGGAAC GTGAACTGCG GAGCTGCAAG 
CGGCAGGTGC GGGAGATCGA GAAGCTGCTG CATCACACAG AACGGCTGTA CCAGAACGCA 
GAAAGCAACA ACCAGGAGCT CCGCACGCAG GTGGAAGAAC TCAGTAAAAT ACTCCAACGT 
GGGAGAAATG AAGATAATAA AAAGTCTGAT GTAGAAGTAC AAACAGAGAA CCATGCTCCT 
TGGTCAATCT CAGATTATTT TTATCAGACG TACTACAATG ACGTTAGTCT TCCAAATAAA 
GTGACTGAAC TGTCAGATCA ACAAGATCAA GCTATCGAAA CTTCTATTTT GAATTCTAAA 
GACCATTTAC AAGTAGAAAA TGATGCTTAC CCTGGTACCG ATAGAACAGA AAATGTTAAA 
TATAGACAAG TGGACCATTT TGCCTCAAAT TCACAGGAGC CAGCATCTGC ATTAGCAACA 
GAAGATACCT CCTTAGAAGG CTCATCATTA GCTGAAAGTT TGAGAGCTGC AGCAGAAGCG 
GCTGTATCAC AGACTGGATT TAGTTATGAT GAAAATACTG GACTGTATTT TGACCACAGC 
ACTGGTTTCT ATTATGATTC TGAAAATCAA CTCTATTATG ATCCTTCCAC TGGAATTTAT 
TACTATTGTG ATGTGGAAAG TGGTCGTTAT CAGTTTCATT CTCGAGTAGA TTTGCAACCT 
TATCCGACTT CTAGCACAAA ACAAAGTAAA GATAAAAAAT TGAAGAAGAA AAGAAAAGAT 
CCAGATTCTT CTGCAACAAA TGAGGAAAAG GATTTGAACT CAGAGGATCA AAAAGCCTTC 
AGTGTTGAAC ATACAAGCTG CAATGAGGAA GAAAATTTCG CAAATATGAA AAAGAAGGCC 
AAAATAGGCA TTCATCACAA AAATAGTCCC CCCAAAGTCA CTGTTCCAAC TAGTGGAAAT 
ACTATAGAGT CTCCTCTTCA TGAAAACATC TCTAATTCAA CATCATTTAA AGATGAGAAA 
ATCATGGAGA CTGATAGTGA ACCAGAGGAA GGTGAAATTA CAGACTCTCA GACTGAGGAT 
AGTTATGACG AAGCCATTAC CAGTGAAGGC AATGTAACTG CAGAAGATAG TGAGGATGAA 
GATGAAGACA AAATTTGGCC CCCATGTATT AGAGTAATTG TCATTAGATC ACCTGTGTTG 
CAGATAGGAT CACTCTTTAT CATTACTGCT GTAAACCCTG CTACAATTGG AAGAGAAAAG 
GATATGGAAC ATACTCTCCG AATCCCTGAA GTTGGTGTCA GTAAGTTTCA TGCAGAAATT 
TATTTTGACC ATGACTTACA AAGTTATGTC CTTGTGGATC AAGGCAGTCA AAATGGCACA 
ATTGTTAATG GAAAACAGAT TCTTCAGCCG AAAACTAAAT GTGACCCTTA CGTACTTGAG 
CATGGAGATG AAGTCAAAAT TGGAGAAACT GTCTTATCCT TTCACATTCA TCCTGGCAGT 
GATACCTGTG ATGGCTGTGA ACCAGGGCAG GTTAGAGCCC ACCTTCGCCT TGATAAGAAA 
GATGAATCTT TTGTTGGTCC AACACTAAGT AAGGAGGAAA AAGAGTTGGA AAGAAGAAAA 
GAATTAAAGA AAATACGAGT AAAATATGGT TTACAGAATA CAGAATACGA AGATGAAAAG 
ACATTGAAGA ATCCAAAATA TAAAGATAGA GCTGGAAAAC GTAGGGAGCA GGTTGGAAGT 
GAAGGAACTT TCCAAAGAGA TGATGCTCCT GCATCTGTTC ATTCTGAAAT TACTGATAGC 
AACAAAGGTC GGAAGATGTT GGAGAAGATG GGTTGGAAGA AAGGAGAGGG CCTGGGGAAG 
GATGGTGGAG GAATGAAAAC GCCGATCCAG CTTCAGCTTC GGCGAACACA TGCAGGCTTG 
GGGACAGGCA AACCATCCTC ATTTGAAGAT GTTCACCTTC TCCAAAACAA GAACAAAAAA 
AACTGGGACA AAGCACGAGA GCGGTTTACT GAAAACTTCC CAGAAACTAA GCCTCAAAAA 
GATGACCCAG GGACCATGCC TTGGGTAAAA GGGACTTTAG AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AGGF1 ( NM_018046.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_060516.2 Homo sapiens angiogenic factor with G-patch and FHA domains 1 (AGGF1), mRNA.

Price & Availability↑

CloneID	OHu23381
Clone ID Related Accession (Same CDS sequence)	NM_018046.4 , NM_018046.5
Accession Version	NM_018046.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2145bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	angiogenic factor with G patch and FHA domains 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI561566.1, AY500994.1, AC008581.11, DR157679.1, BX648120.1 and AI453097.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_018046.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.112465.1, SRR1660803.183314.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000312916.12/ ENSP00000316109.7 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCCTCGG AGGCGCCGTC CCCGCCGCGG TCGCCGCCGC CGCCCACCTC CCCCGAGCCT 
GAGCTGGCCC AGCTAAGGCG GAAGGTGGAG AAGTTGGAAC GTGAACTGCG GAGCTGCAAG 
CGGCAGGTGC GGGAGATCGA GAAGCTGCTG CATCACACAG AACGGCTGTA CCAGAACGCA 
GAAAGCAACA ACCAGGAGCT CCGCACGCAG GTGGAAGAAC TCAGTAAAAT ACTCCAACGT 
GGGAGAAATG AAGATAATAA AAAGTCTGAT GTAGAAGTAC AAACAGAGAA CCATGCTCCT 
TGGTCAATCT CAGATTATTT TTATCAGACG TACTACAATG ACGTTAGTCT TCCAAATAAA 
GTGACTGAAC TGTCAGATCA ACAAGATCAA GCTATCGAAA CTTCTATTTT GAATTCTAAA 
GACCATTTAC AAGTAGAAAA TGATGCTTAC CCTGGTACCG ATAGAACAGA AAATGTTAAA 
TATAGACAAG TGGACCATTT TGCCTCAAAT TCACAGGAGC CAGCATCTGC ATTAGCAACA 
GAAGATACCT CCTTAGAAGG CTCATCATTA GCTGAAAGTT TGAGAGCTGC AGCAGAAGCG 
GCTGTATCAC AGACTGGATT TAGTTATGAT GAAAATACTG GACTGTATTT TGACCACAGC 
ACTGGTTTCT ATTATGATTC TGAAAATCAA CTCTATTATG ATCCTTCCAC TGGAATTTAT 
TACTATTGTG ATGTGGAAAG TGGTCGTTAT CAGTTTCATT CTCGAGTAGA TTTGCAACCT 
TATCCGACTT CTAGCACAAA ACAAAGTAAA GATAAAAAAT TGAAGAAGAA AAGAAAAGAT 
CCAGATTCTT CTGCAACAAA TGAGGAAAAG GATTTGAACT CAGAGGATCA AAAAGCCTTC 
AGTGTTGAAC ATACAAGCTG CAATGAGGAA GAAAATTTCG CAAATATGAA AAAGAAGGCC 
AAAATAGGCA TTCATCACAA AAATAGTCCC CCCAAAGTCA CTGTTCCAAC TAGTGGAAAT 
ACTATAGAGT CTCCTCTTCA TGAAAACATC TCTAATTCAA CATCATTTAA AGATGAGAAA 
ATCATGGAGA CTGATAGTGA ACCAGAGGAA GGTGAAATTA CAGACTCTCA GACTGAGGAT 
AGTTATGACG AAGCCATTAC CAGTGAAGGC AATGTAACTG CAGAAGATAG TGAGGATGAA 
GATGAAGACA AAATTTGGCC CCCATGTATT AGAGTAATTG TCATTAGATC ACCTGTGTTG 
CAGATAGGAT CACTCTTTAT CATTACTGCT GTAAACCCTG CTACAATTGG AAGAGAAAAG 
GATATGGAAC ATACTCTCCG AATCCCTGAA GTTGGTGTCA GTAAGTTTCA TGCAGAAATT 
TATTTTGACC ATGACTTACA AAGTTATGTC CTTGTGGATC AAGGCAGTCA AAATGGCACA 
ATTGTTAATG GAAAACAGAT TCTTCAGCCG AAAACTAAAT GTGACCCTTA CGTACTTGAG 
CATGGAGATG AAGTCAAAAT TGGAGAAACT GTCTTATCCT TTCACATTCA TCCTGGCAGT 
GATACCTGTG ATGGCTGTGA ACCAGGGCAG GTTAGAGCCC ACCTTCGCCT TGATAAGAAA 
GATGAATCTT TTGTTGGTCC AACACTAAGT AAGGAGGAAA AAGAGTTGGA AAGAAGAAAA 
GAATTAAAGA AAATACGAGT AAAATATGGT TTACAGAATA CAGAATACGA AGATGAAAAG 
ACATTGAAGA ATCCAAAATA TAAAGATAGA GCTGGAAAAC GTAGGGAGCA GGTTGGAAGT 
GAAGGAACTT TCCAAAGAGA TGATGCTCCT GCATCTGTTC ATTCTGAAAT TACTGATAGC 
AACAAAGGTC GGAAGATGTT GGAGAAGATG GGTTGGAAGA AAGGAGAGGG CCTGGGGAAG 
GATGGTGGAG GAATGAAAAC GCCGATCCAG CTTCAGCTTC GGCGAACACA TGCAGGCTTG 
GGGACAGGCA AACCATCCTC ATTTGAAGAT GTTCACCTTC TCCAAAACAA GAACAAAAAA 
AACTGGGACA AAGCACGAGA GCGGTTTACT GAAAACTTCC CAGAAACTAA GCCTCAAAAA 
GATGACCCAG GGACCATGCC TTGGGTAAAA GGGACTTTAG AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060516.2
CDS	364..2508
Translation	MASEAPSPPRSPPPPTSPEPELAQLRRKVEKLERELRSCKRQVREIEKLLHHTERLYQNAESNNQELRTQVEELSKILQRGRNEDNKKSDVEVQTENHAPWSISDYFYQTYYNDVSLPNKVTELSDQQDQAIETSILNSKDHLQVENDAYPGTDRTENVKYRQVDHFASNSQEPASALATEDTSLEGSSLAESLRAAAEAAVSQTGFSYDENTGLYFDHSTGFYYDSENQLYYDPSTGIYYYCDVESGRYQFHSRVDLQPYPTSSTKQSKDKKLKKKRKDPDSSATNEEKDLNSEDQKAFSVEHTSCNEEENFANMKKKAKIGIHHKNSPPKVTVPTSGNTIESPLHENISNSTSFKDEKIMETDSEPEEGEITDSQTEDSYDEAITSEGNVTAEDSEDEDEDKIWPPCIRVIVIRSPVLQIGSLFIITAVNPATIGREKDMEHTLRIPEVGVSKFHAEIYFDHDLQSYVLVDQGSQNGTIVNGKQILQPKTKCDPYVLEHGDEVKIGETVLSFHIHPGSDTCDGCEPGQVRAHLRLDKKDESFVGPTLSKEEKELERRKELKKIRVKYGLQNTEYEDEKTLKNPKYKDRAGKRREQVGSEGTFQRDDAPASVHSEITDSNKGRKMLEKMGWKKGEGLGKDGGGMKTPIQLQLRRTHAGLGTGKPSSFEDVHLLQNKNKKNWDKARERFTENFPETKPQKDDPGTMPWVKGTLE

Target ORF information:

RefSeq Version	NM_018046.5
Organism	Homo sapiens(human)
Definition	Homo sapiens angiogenic factor with G-patch and FHA domains 1 (AGGF1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018046.5

ORF Insert Sequence:

ATGGCCTCGG AGGCGCCGTC CCCGCCGCGG TCGCCGCCGC CGCCCACCTC CCCCGAGCCT 
GAGCTGGCCC AGCTAAGGCG GAAGGTGGAG AAGTTGGAAC GTGAACTGCG GAGCTGCAAG 
CGGCAGGTGC GGGAGATCGA GAAGCTGCTG CATCACACAG AACGGCTGTA CCAGAACGCA 
GAAAGCAACA ACCAGGAGCT CCGCACGCAG GTGGAAGAAC TCAGTAAAAT ACTCCAACGT 
GGGAGAAATG AAGATAATAA AAAGTCTGAT GTAGAAGTAC AAACAGAGAA CCATGCTCCT 
TGGTCAATCT CAGATTATTT TTATCAGACG TACTACAATG ACGTTAGTCT TCCAAATAAA 
GTGACTGAAC TGTCAGATCA ACAAGATCAA GCTATCGAAA CTTCTATTTT GAATTCTAAA 
GACCATTTAC AAGTAGAAAA TGATGCTTAC CCTGGTACCG ATAGAACAGA AAATGTTAAA 
TATAGACAAG TGGACCATTT TGCCTCAAAT TCACAGGAGC CAGCATCTGC ATTAGCAACA 
GAAGATACCT CCTTAGAAGG CTCATCATTA GCTGAAAGTT TGAGAGCTGC AGCAGAAGCG 
GCTGTATCAC AGACTGGATT TAGTTATGAT GAAAATACTG GACTGTATTT TGACCACAGC 
ACTGGTTTCT ATTATGATTC TGAAAATCAA CTCTATTATG ATCCTTCCAC TGGAATTTAT 
TACTATTGTG ATGTGGAAAG TGGTCGTTAT CAGTTTCATT CTCGAGTAGA TTTGCAACCT 
TATCCGACTT CTAGCACAAA ACAAAGTAAA GATAAAAAAT TGAAGAAGAA AAGAAAAGAT 
CCAGATTCTT CTGCAACAAA TGAGGAAAAG GATTTGAACT CAGAGGATCA AAAAGCCTTC 
AGTGTTGAAC ATACAAGCTG CAATGAGGAA GAAAATTTCG CAAATATGAA AAAGAAGGCC 
AAAATAGGCA TTCATCACAA AAATAGTCCC CCCAAAGTCA CTGTTCCAAC TAGTGGAAAT 
ACTATAGAGT CTCCTCTTCA TGAAAACATC TCTAATTCAA CATCATTTAA AGATGAGAAA 
ATCATGGAGA CTGATAGTGA ACCAGAGGAA GGTGAAATTA CAGACTCTCA GACTGAGGAT 
AGTTATGACG AAGCCATTAC CAGTGAAGGC AATGTAACTG CAGAAGATAG TGAGGATGAA 
GATGAAGACA AAATTTGGCC CCCATGTATT AGAGTAATTG TCATTAGATC ACCTGTGTTG 
CAGATAGGAT CACTCTTTAT CATTACTGCT GTAAACCCTG CTACAATTGG AAGAGAAAAG 
GATATGGAAC ATACTCTCCG AATCCCTGAA GTTGGTGTCA GTAAGTTTCA TGCAGAAATT 
TATTTTGACC ATGACTTACA AAGTTATGTC CTTGTGGATC AAGGCAGTCA AAATGGCACA 
ATTGTTAATG GAAAACAGAT TCTTCAGCCG AAAACTAAAT GTGACCCTTA CGTACTTGAG 
CATGGAGATG AAGTCAAAAT TGGAGAAACT GTCTTATCCT TTCACATTCA TCCTGGCAGT 
GATACCTGTG ATGGCTGTGA ACCAGGGCAG GTTAGAGCCC ACCTTCGCCT TGATAAGAAA 
GATGAATCTT TTGTTGGTCC AACACTAAGT AAGGAGGAAA AAGAGTTGGA AAGAAGAAAA 
GAATTAAAGA AAATACGAGT AAAATATGGT TTACAGAATA CAGAATACGA AGATGAAAAG 
ACATTGAAGA ATCCAAAATA TAAAGATAGA GCTGGAAAAC GTAGGGAGCA GGTTGGAAGT 
GAAGGAACTT TCCAAAGAGA TGATGCTCCT GCATCTGTTC ATTCTGAAAT TACTGATAGC 
AACAAAGGTC GGAAGATGTT GGAGAAGATG GGTTGGAAGA AAGGAGAGGG CCTGGGGAAG 
GATGGTGGAG GAATGAAAAC GCCGATCCAG CTTCAGCTTC GGCGAACACA TGCAGGCTTG 
GGGACAGGCA AACCATCCTC ATTTGAAGAT GTTCACCTTC TCCAAAACAA GAACAAAAAA 
AACTGGGACA AAGCACGAGA GCGGTTTACT GAAAACTTCC CAGAAACTAA GCCTCAAAAA 
GATGACCCAG GGACCATGCC TTGGGTAAAA GGGACTTTAG AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Angiogenic Factor With G Patch and FHA Domains 1 Is a Novel Regulator of Vascular Injury.
Arteriosclerosis, thrombosis, and vascular biology37(4)675-684(2017 Apr)
Zhou B,Zeng S,Li N,Yu L,Yang G,Yang Y,Zhang X,Fang M,Xia J,Xu Y

High Expression of Angiogenic Factor with G-Patch and FHA Domain1 (AGGF1) Predicts Poor Prognosis in Gastric Cancer.
Medical science monitor : international medical journal of experimental and clinical research231286-1294(2017 Mar)
Yao HH,Wang BJ,Wu Y,Huang Q

Polymorphic Variants rs13155212 (T/C) and rs7704267 (G/C) in the AGGF1 Gene and Risk of Varicose Veins of the Lower Extremities in the Population of Ethnic Russians.
Bulletin of experimental biology and medicine161(5)698-702(2016 Sep)
Shadrina AS,Smetanina MA,Sevost'ianova KS,Sokolova EA,Shevela AI,Selivestrov EI,Demekhova MY,Shonov OA,Ilyukhin EA,Voronina EN,Zolotukhin IA,Kirienko AI,Filipenko ML

Overexpression of AGGF1 is correlated with angiogenesis and poor prognosis of hepatocellular carcinoma.
Medical oncology (Northwood, London, England)32(4)131(2015 Apr)
Wang W,Li GY,Zhu JY,Huang DB,Zhou HC,Zhong W,Ji CS

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AGGF1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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