Gene Symbol | PPP1R3A |
Entrez Gene ID | 5506 |
Full Name | protein phosphatase 1 regulatory subunit 3A |
Synonyms | GM,PP1G,PPP1R3 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | The glycogen-associated form of protein phosphatase-1 (PP1) derived from skeletal muscle is a heterodimer composed of a 37-kD catalytic subunit and a 124-kD targeting and regulatory subunit. This gene encodes the regulatory subunit which binds to muscle glycogen with high affinity, thereby enhancing dephosphorylation of glycogen-bound substrates for PP1 such as glycogen synthase and glycogen phosphorylase kinase. [provided by RefSeq, Jul 2008]. |
Disorder MIM: | |
Disorder Html: | Insulin resistance, severe, digenic, 125853 (3) |