KANSL2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	KANSL2
Entrez Gene ID	54934
Full Name	KAT8 regulatory NSL complex subunit 2
Synonyms	C12orf41,NSL2
General protein information	Preferred Names KAT8 regulatory NSL complex subunit 2 Names KAT8 regulatory NSL complex subunit 2 NSL complex protein NSL2 non-specific lethal 2 homolog
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 12 Map Location: 12q13.11
Disorder MIM:	615488

mRNA and Protein(s)

mRNA	Protein	Name
NM_017822.3	NP_060292.3	KAT8 regulatory NSL complex subunit 2
NM_017822.4	NP_060292.3	KAT8 regulatory NSL complex subunit 2

Pathways from BioSystems

Homologies

Homo sapiens (human)	KANSL2	NP_060292.3
Mus musculus (house mouse)	Kansl2	NP_598475.2
Xenopus tropicalis (tropical clawed frog)	kansl2	NP_001096493.1
Pan troglodytes (chimpanzee)	KANSL2	XP_509031.4
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP006680	XP_316718.4
	LOC709517	XP_001098054.2
Bos taurus (cattle)	KANSL2	NP_001019742.2
Rattus norvegicus (Norway rat)	Kansl2	NP_001004244.2
Gallus gallus (chicken)	KANSL2	XP_004950485.1
Canis lupus familiaris (dog)	KANSL2	XP_005636954.1
Danio rerio (zebrafish)	kansl2	NP_001005990.1
Drosophila melanogaster (fruit fly)	dgt1	NP_651737.1

Gene Ontology
Bibliography

Related articles in PubMed

A High-Density Map for Navigating the Human Polycomb Complexome.
Hauri S, Comoglio F, Seimiya M, Gerstung M, Glatter T, Hansen K, Aebersold R, Paro R, Gstaiger M, Beisel C
Cell reports17(2)583-595(2016 10)

The NSL Chromatin-Modifying Complex Subunit KANSL2 Regulates Cancer Stem-like Properties in Glioblastoma That Contribute to Tumorigenesis.
Ferreyra Solari NE, Belforte FS, Canedo L, Videla-Richardson GA, Espinosa JM, Rossi M, Serna E, Riudavets MA, Martinetto H, Sevlever G, Perez-Castro C
Cancer research76(18)5383-94(2016 Sep)

Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.
Goldstein JI, Jarskog LF, Hilliard C, Alfirevic A, Duncan L, Fourches D, Huang H, Lek M, Neale BM, Ripke S, Shianna K, Szatkiewicz JP, Tropsha A, van den Oord EJ, Cascorbi I, Dettling M, Gazit E, Goff DC, Holden AL, Kelly DL, Malhotra AK, Nielsen J, Pirmohamed M, Rujescu D, Werge T, Levy DL, Josiassen RC, Kennedy JL, Lieberman JA, Daly MJ, Sullivan PF
Nature communications54757(2014 Sep)

Structural analysis of the KANSL1/WDR5/KANSL2 complex reveals that WDR5 is required for efficient assembly and chromatin targeting of the NSL complex.
Dias J, Van Nguyen N, Georgiev P, Gaub A, Brettschneider J, Cusack S, Kadlec J, Akhtar A
Genes & development28(9)929-42(2014 May)

Subunit composition and substrate specificity of a MOF-containing histone acetyltransferase distinct from the male-specific lethal (MSL) complex.
Cai Y, Jin J, Swanson SK, Cole MD, Choi SH, Florens L, Washburn MP, Conaway JW, Conaway RC
The Journal of biological chemistry285(7)4268-72(2010 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

our findings indicate that KANSL2 acts to regulate the stem cell population in glioblastoma
Title: The NSL Chromatin-Modifying Complex Subunit KANSL2 Regulates Cancer Stem-like Properties in Glioblastoma That Contribute to Tumorigenesis.

The following KANSL2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KANSL2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu31070	NM_017822.4 Latest version!	Homo sapiens KAT8 regulatory NSL complex subunit 2 (KANSL2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu31070	NM_017822.3	Homo sapiens KAT8 regulatory NSL complex subunit 2 (KANSL2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

KANSL2 ( NM_017822.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_060292.3 Homo sapiens KAT8 regulatory NSL complex subunit 2 (KANSL2), mRNA.

Price & Availability↑

CloneID	OHu31070
Clone ID Related Accession (Same CDS sequence)	NM_017822.3 , NM_017822.4
Accession Version	NM_017822.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1479bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-17
Organism	Homo sapiens(human)
Product	KAT8 regulatory NSL complex subunit 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA278834.1, BC009746.2, BG760446.1 and BM672156.1. On Aug 2, 2007 this sequence version replaced NM_017822.2. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.140524.1, SRR1803616.209831.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAACAGGA TTCGGATTCA CGTCTTGCCA ACCAATCGGG GGAGGATCAC TCCAGTGCCC 
AGGTCTCAGG AACCTCTGTC TTGTGCATTC ACTCATCGTC CATGCTCTCA CCCTCGTCTG 
GAGGGGCAGG AGTTTTGCAT TAAGCATATC CTTGAAGACA AGAATGCACC CTTCAAGCAG 
TGTAGTTATA TATCGACGAA GAATGGAAAA AGATGTCCCA ATGCTGCCCC AAAGCCAGAG 
AAGAAAGATG GGGTGTCCTT CTGTGCTGAA CATGTCCGTA GGAATGCCCT GGCACTTCAT 
GCTCAAATGA AGAAGACCAA CCCAGGGCCT GTGGGTGAAA CACTCCTGTG CCAGCTGAGC 
TCATATGCTA AGACAGAGCT GGGGTCTCAG ACTCCAGAAA GTAGTCGCAG TGAAGCCAGC 
CGAATACTAG ATGAAGACAG CTGGAGTGAT GGGGAGCAGG AACCCATTAC TGTGGATCAG 
ACATGGAGAG GTGACCCTGA CAGTGAAGCT GATAGCATAG ACAGTGATCA AGAAGATCCC 
CTAAAACATG CTGGTGTCTA CACAGCAGAA GAAGTGGCCC TGATTATGCG TGAAAAGCTA 
ATTCGTTTGC AGTCGTTGTA TATTGATCAG TTTAAACGAC TTCAGCATCT GCTCAAGGAG 
AAGAAGCGCC GATACTTACA TAATCGCAAA GTGGAACATG AAGCTCTAGG CAGTAGTCTC 
CTGACTGGCC CAGAGGGACT TTTGGCCAAA GAACGAGAGA ACTTAAAGCG ATTAAAATGT 
CTGCGACGAT ACCGCCAGCG CTATGGAGTG GAAGCCTTAC TGCATAGGCA GTTGAAGGAA 
CGGAGAATGC TGGCCACAGA TGGTGCTGCC CAACAGGCCC ATACCACTCG TTCCAGTCAG 
AGGTGCTTGG CCTTTGTGGA TGATGTTCGT TGTTCCAATC AGTCTCTTCC AATGACCAGA 
CACTGCCTTA CCCATATTTG TCAGGATACG AATCAGGTTC TCTTCAAGTG CTGCCAGGGA 
TCTGAAGAGG TACCCTGCAA CAAACCTGTT CCTGTAAGCC TCTCTGAGGA TCCCTGCTGC 
CCACTGCATT TCCAGTTGCC TCCTCAGATG TATAAGCCCG AGCAGGTACT GTCTGTGCCA 
GACGATCTGG AAGCCGGCCC CATGGATCTG TACTTGAGTG CTGCTGAGCT TCAGCCCACT 
GAGAGTTTAC CTCTGGAGTT CAGTGATGAC TTGGATGTTG TGGGTGATGG TATGCAGTGT 
CCTCCTTCAC CTTTGCTTTT TGATCCTTCA CTAACCCTTG AAGATCATTT AGTCAAAGAA 
ATTGCTGAAG ACCCAGTGGA TATTTTGGGC CAGATGCAGA TGGCTGGAGA TGGGTGCAGA 
TCCCAGGGAT CTCGAAATTC TGAGAAAGCC TCTGCACCAT TGTCTCAGAG TGGATTGGCT 
ACTGCAAATG GGAAGCCAGA ACCCACTTCT ATTAGTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060292.3
CDS	76..1554
Translation	MNRIRIHVLPTNRGRITPVPRSQEPLSCAFTHRPCSHPRLEGQEFCIKHILEDKNAPFKQCSYISTKNGKRCPNAAPKPEKKDGVSFCAEHVRRNALALHAQMKKTNPGPVGETLLCQLSSYAKTELGSQTPESSRSEASRILDEDSWSDGEQEPITVDQTWRGDPDSEADSIDSDQEDPLKHAGVYTAEEVALIMREKLIRLQSLYIDQFKRLQHLLKEKKRRYLHNRKVEHEALGSSLLTGPEGLLAKERENLKRLKCLRRYRQRYGVEALLHRQLKERRMLATDGAAQQAHTTRSSQRCLAFVDDVRCSNQSLPMTRHCLTHICQDTNQVLFKCCQGSEEVPCNKPVPVSLSEDPCCPLHFQLPPQMYKPEQVLSVPDDLEAGPMDLYLSAAELQPTESLPLEFSDDLDVVGDGMQCPPSPLLFDPSLTLEDHLVKEIAEDPVDILGQMQMAGDGCRSQGSRNSEKASAPLSQSGLATANGKPEPTSIS

Target ORF information:

RefSeq Version	NM_017822.3
Organism	Homo sapiens(human)
Definition	Homo sapiens KAT8 regulatory NSL complex subunit 2 (KANSL2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_017822.3

ORF Insert Sequence:

ATGAACAGGA TTCGGATTCA CGTCTTGCCA ACCAATCGGG GGAGGATCAC TCCAGTGCCC 
AGGTCTCAGG AACCTCTGTC TTGTGCATTC ACTCATCGTC CATGCTCTCA CCCTCGTCTG 
GAGGGGCAGG AGTTTTGCAT TAAGCATATC CTTGAAGACA AGAATGCACC CTTCAAGCAG 
TGTAGTTATA TATCGACGAA GAATGGAAAA AGATGTCCCA ATGCTGCCCC AAAGCCAGAG 
AAGAAAGATG GGGTGTCCTT CTGTGCTGAA CATGTCCGTA GGAATGCCCT GGCACTTCAT 
GCTCAAATGA AGAAGACCAA CCCAGGGCCT GTGGGTGAAA CACTCCTGTG CCAGCTGAGC 
TCATATGCTA AGACAGAGCT GGGGTCTCAG ACTCCAGAAA GTAGTCGCAG TGAAGCCAGC 
CGAATACTAG ATGAAGACAG CTGGAGTGAT GGGGAGCAGG AACCCATTAC TGTGGATCAG 
ACATGGAGAG GTGACCCTGA CAGTGAAGCT GATAGCATAG ACAGTGATCA AGAAGATCCC 
CTAAAACATG CTGGTGTCTA CACAGCAGAA GAAGTGGCCC TGATTATGCG TGAAAAGCTA 
ATTCGTTTGC AGTCGTTGTA TATTGATCAG TTTAAACGAC TTCAGCATCT GCTCAAGGAG 
AAGAAGCGCC GATACTTACA TAATCGCAAA GTGGAACATG AAGCTCTAGG CAGTAGTCTC 
CTGACTGGCC CAGAGGGACT TTTGGCCAAA GAACGAGAGA ACTTAAAGCG ATTAAAATGT 
CTGCGACGAT ACCGCCAGCG CTATGGAGTG GAAGCCTTAC TGCATAGGCA GTTGAAGGAA 
CGGAGAATGC TGGCCACAGA TGGTGCTGCC CAACAGGCCC ATACCACTCG TTCCAGTCAG 
AGGTGCTTGG CCTTTGTGGA TGATGTTCGT TGTTCCAATC AGTCTCTTCC AATGACCAGA 
CACTGCCTTA CCCATATTTG TCAGGATACG AATCAGGTTC TCTTCAAGTG CTGCCAGGGA 
TCTGAAGAGG TACCCTGCAA CAAACCTGTT CCTGTAAGCC TCTCTGAGGA TCCCTGCTGC 
CCACTGCATT TCCAGTTGCC TCCTCAGATG TATAAGCCCG AGCAGGTACT GTCTGTGCCA 
GACGATCTGG AAGCCGGCCC CATGGATCTG TACTTGAGTG CTGCTGAGCT TCAGCCCACT 
GAGAGTTTAC CTCTGGAGTT CAGTGATGAC TTGGATGTTG TGGGTGATGG TATGCAGTGT 
CCTCCTTCAC CTTTGCTTTT TGATCCTTCA CTAACCCTTG AAGATCATTT AGTCAAAGAA 
ATTGCTGAAG ACCCAGTGGA TATTTTGGGC CAGATGCAGA TGGCTGGAGA TGGGTGCAGA 
TCCCAGGGAT CTCGAAATTC TGAGAAAGCC TCTGCACCAT TGTCTCAGAG TGGATTGGCT 
ACTGCAAATG GGAAGCCAGA ACCCACTTCT ATTAGTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KANSL2 ( NM_017822.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_060292.3 Homo sapiens KAT8 regulatory NSL complex subunit 2 (KANSL2), mRNA.

Price & Availability↑

CloneID	OHu31070
Clone ID Related Accession (Same CDS sequence)	NM_017822.3 , NM_017822.4
Accession Version	NM_017822.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1479bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-09
Organism	Homo sapiens(human)
Product	KAT8 regulatory NSL complex subunit 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA278834.1, BC009746.2, BG760446.1 and BM672156.1. On Jun 2, 2019 this sequence version replaced NM_017822.3. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.61942.1, SRR1803615.50506.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAACAGGA TTCGGATTCA CGTCTTGCCA ACCAATCGGG GGAGGATCAC TCCAGTGCCC 
AGGTCTCAGG AACCTCTGTC TTGTGCATTC ACTCATCGTC CATGCTCTCA CCCTCGTCTG 
GAGGGGCAGG AGTTTTGCAT TAAGCATATC CTTGAAGACA AGAATGCACC CTTCAAGCAG 
TGTAGTTATA TATCGACGAA GAATGGAAAA AGATGTCCCA ATGCTGCCCC AAAGCCAGAG 
AAGAAAGATG GGGTGTCCTT CTGTGCTGAA CATGTCCGTA GGAATGCCCT GGCACTTCAT 
GCTCAAATGA AGAAGACCAA CCCAGGGCCT GTGGGTGAAA CACTCCTGTG CCAGCTGAGC 
TCATATGCTA AGACAGAGCT GGGGTCTCAG ACTCCAGAAA GTAGTCGCAG TGAAGCCAGC 
CGAATACTAG ATGAAGACAG CTGGAGTGAT GGGGAGCAGG AACCCATTAC TGTGGATCAG 
ACATGGAGAG GTGACCCTGA CAGTGAAGCT GATAGCATAG ACAGTGATCA AGAAGATCCC 
CTAAAACATG CTGGTGTCTA CACAGCAGAA GAAGTGGCCC TGATTATGCG TGAAAAGCTA 
ATTCGTTTGC AGTCGTTGTA TATTGATCAG TTTAAACGAC TTCAGCATCT GCTCAAGGAG 
AAGAAGCGCC GATACTTACA TAATCGCAAA GTGGAACATG AAGCTCTAGG CAGTAGTCTC 
CTGACTGGCC CAGAGGGACT TTTGGCCAAA GAACGAGAGA ACTTAAAGCG ATTAAAATGT 
CTGCGACGAT ACCGCCAGCG CTATGGAGTG GAAGCCTTAC TGCATAGGCA GTTGAAGGAA 
CGGAGAATGC TGGCCACAGA TGGTGCTGCC CAACAGGCCC ATACCACTCG TTCCAGTCAG 
AGGTGCTTGG CCTTTGTGGA TGATGTTCGT TGTTCCAATC AGTCTCTTCC AATGACCAGA 
CACTGCCTTA CCCATATTTG TCAGGATACG AATCAGGTTC TCTTCAAGTG CTGCCAGGGA 
TCTGAAGAGG TACCCTGCAA CAAACCTGTT CCTGTAAGCC TCTCTGAGGA TCCCTGCTGC 
CCACTGCATT TCCAGTTGCC TCCTCAGATG TATAAGCCCG AGCAGGTACT GTCTGTGCCA 
GACGATCTGG AAGCCGGCCC CATGGATCTG TACTTGAGTG CTGCTGAGCT TCAGCCCACT 
GAGAGTTTAC CTCTGGAGTT CAGTGATGAC TTGGATGTTG TGGGTGATGG TATGCAGTGT 
CCTCCTTCAC CTTTGCTTTT TGATCCTTCA CTAACCCTTG AAGATCATTT AGTCAAAGAA 
ATTGCTGAAG ACCCAGTGGA TATTTTGGGC CAGATGCAGA TGGCTGGAGA TGGGTGCAGA 
TCCCAGGGAT CTCGAAATTC TGAGAAAGCC TCTGCACCAT TGTCTCAGAG TGGATTGGCT 
ACTGCAAATG GGAAGCCAGA ACCCACTTCT ATTAGTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060292.3
CDS	62..1540
Translation	MNRIRIHVLPTNRGRITPVPRSQEPLSCAFTHRPCSHPRLEGQEFCIKHILEDKNAPFKQCSYISTKNGKRCPNAAPKPEKKDGVSFCAEHVRRNALALHAQMKKTNPGPVGETLLCQLSSYAKTELGSQTPESSRSEASRILDEDSWSDGEQEPITVDQTWRGDPDSEADSIDSDQEDPLKHAGVYTAEEVALIMREKLIRLQSLYIDQFKRLQHLLKEKKRRYLHNRKVEHEALGSSLLTGPEGLLAKERENLKRLKCLRRYRQRYGVEALLHRQLKERRMLATDGAAQQAHTTRSSQRCLAFVDDVRCSNQSLPMTRHCLTHICQDTNQVLFKCCQGSEEVPCNKPVPVSLSEDPCCPLHFQLPPQMYKPEQVLSVPDDLEAGPMDLYLSAAELQPTESLPLEFSDDLDVVGDGMQCPPSPLLFDPSLTLEDHLVKEIAEDPVDILGQMQMAGDGCRSQGSRNSEKASAPLSQSGLATANGKPEPTSIS

Target ORF information:

RefSeq Version	NM_017822.4
Organism	Homo sapiens(human)
Definition	Homo sapiens KAT8 regulatory NSL complex subunit 2 (KANSL2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_017822.4

ORF Insert Sequence:

ATGAACAGGA TTCGGATTCA CGTCTTGCCA ACCAATCGGG GGAGGATCAC TCCAGTGCCC 
AGGTCTCAGG AACCTCTGTC TTGTGCATTC ACTCATCGTC CATGCTCTCA CCCTCGTCTG 
GAGGGGCAGG AGTTTTGCAT TAAGCATATC CTTGAAGACA AGAATGCACC CTTCAAGCAG 
TGTAGTTATA TATCGACGAA GAATGGAAAA AGATGTCCCA ATGCTGCCCC AAAGCCAGAG 
AAGAAAGATG GGGTGTCCTT CTGTGCTGAA CATGTCCGTA GGAATGCCCT GGCACTTCAT 
GCTCAAATGA AGAAGACCAA CCCAGGGCCT GTGGGTGAAA CACTCCTGTG CCAGCTGAGC 
TCATATGCTA AGACAGAGCT GGGGTCTCAG ACTCCAGAAA GTAGTCGCAG TGAAGCCAGC 
CGAATACTAG ATGAAGACAG CTGGAGTGAT GGGGAGCAGG AACCCATTAC TGTGGATCAG 
ACATGGAGAG GTGACCCTGA CAGTGAAGCT GATAGCATAG ACAGTGATCA AGAAGATCCC 
CTAAAACATG CTGGTGTCTA CACAGCAGAA GAAGTGGCCC TGATTATGCG TGAAAAGCTA 
ATTCGTTTGC AGTCGTTGTA TATTGATCAG TTTAAACGAC TTCAGCATCT GCTCAAGGAG 
AAGAAGCGCC GATACTTACA TAATCGCAAA GTGGAACATG AAGCTCTAGG CAGTAGTCTC 
CTGACTGGCC CAGAGGGACT TTTGGCCAAA GAACGAGAGA ACTTAAAGCG ATTAAAATGT 
CTGCGACGAT ACCGCCAGCG CTATGGAGTG GAAGCCTTAC TGCATAGGCA GTTGAAGGAA 
CGGAGAATGC TGGCCACAGA TGGTGCTGCC CAACAGGCCC ATACCACTCG TTCCAGTCAG 
AGGTGCTTGG CCTTTGTGGA TGATGTTCGT TGTTCCAATC AGTCTCTTCC AATGACCAGA 
CACTGCCTTA CCCATATTTG TCAGGATACG AATCAGGTTC TCTTCAAGTG CTGCCAGGGA 
TCTGAAGAGG TACCCTGCAA CAAACCTGTT CCTGTAAGCC TCTCTGAGGA TCCCTGCTGC 
CCACTGCATT TCCAGTTGCC TCCTCAGATG TATAAGCCCG AGCAGGTACT GTCTGTGCCA 
GACGATCTGG AAGCCGGCCC CATGGATCTG TACTTGAGTG CTGCTGAGCT TCAGCCCACT 
GAGAGTTTAC CTCTGGAGTT CAGTGATGAC TTGGATGTTG TGGGTGATGG TATGCAGTGT 
CCTCCTTCAC CTTTGCTTTT TGATCCTTCA CTAACCCTTG AAGATCATTT AGTCAAAGAA 
ATTGCTGAAG ACCCAGTGGA TATTTTGGGC CAGATGCAGA TGGCTGGAGA TGGGTGCAGA 
TCCCAGGGAT CTCGAAATTC TGAGAAAGCC TCTGCACCAT TGTCTCAGAG TGGATTGGCT 
ACTGCAAATG GGAAGCCAGA ACCCACTTCT ATTAGTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A High-Density Map for Navigating the Human Polycomb Complexome.
Cell reports17(2)583-595(2016 10)
Hauri S,Comoglio F,Seimiya M,Gerstung M,Glatter T,Hansen K,Aebersold R,Paro R,Gstaiger M,Beisel C

The NSL Chromatin-Modifying Complex Subunit KANSL2 Regulates Cancer Stem-like Properties in Glioblastoma That Contribute to Tumorigenesis.
Cancer research76(18)5383-94(2016 Sep)
Ferreyra Solari NE,Belforte FS,Canedo L,Videla-Richardson GA,Espinosa JM,Rossi M,Serna E,Riudavets MA,Martinetto H,Sevlever G,Perez-Castro C

Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.
Nature communications54757(2014 Sep)
Goldstein JI,Jarskog LF,Hilliard C,Alfirevic A,Duncan L,Fourches D,Huang H,Lek M,Neale BM,Ripke S,Shianna K,Szatkiewicz JP,Tropsha A,van den Oord EJ,Cascorbi I,Dettling M,Gazit E,Goff DC,Holden AL,Kelly DL,Malhotra AK,Nielsen J,Pirmohamed M,Rujescu D,Werge T,Levy DL,Josiassen RC,Kennedy JL,Lieberman JA,Daly MJ,Sullivan PF

Structural analysis of the KANSL1/WDR5/KANSL2 complex reveals that WDR5 is required for efficient assembly and chromatin targeting of the NSL complex.
Genes & development28(9)929-42(2014 May)
Dias J,Van Nguyen N,Georgiev P,Gaub A,Brettschneider J,Cusack S,Kadlec J,Akhtar A

Subunit composition and substrate specificity of a MOF-containing histone acetyltransferase distinct from the male-specific lethal (MSL) complex.
The Journal of biological chemistry285(7)4268-72(2010 Feb)
Cai Y,Jin J,Swanson SK,Cole MD,Choi SH,Florens L,Washburn MP,Conaway JW,Conaway RC

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KANSL2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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