Gene Symbol | TET2 |
Entrez Gene ID | 54790 |
Full Name | tet methylcytosine dioxygenase 2 |
Synonyms | KIAA1546,MDS |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defects in this gene have been associated with several myeloproliferative disorders. Two variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]. |
Disorder MIM: | |
Disorder Html: | Myelodysplastic syndrome, somatic, 614286 (3) |