| Gene Symbol | PPARG |
| Entrez Gene ID | 5468 |
| Full Name | peroxisome proliferator activated receptor gamma |
| Synonyms | CIMT1,GLM1,NR1C3,PPARG1,PPARG2,PPARgamma |
| General protein information |
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| Gene Type | protein-coding |
| Organism | Homo sapiens(human) |
| Genome | |
| Summary | This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008]. |
| Disorder MIM: | |
| Disorder Html: | Obesity, severe, 601665 (3); [Obesity, resistance to] (3); Insulin resistance, severe, digenic, 604367 (3); Lipodystrophy, familial partial, type 3, 604367 (3); Carotid intimal medial thickness 1, 609338 (3); {Diabetes, type 2}, 125853 (3) |









































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