LRRN3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	LRRN3
Entrez Gene ID	54674
Full Name	leucine rich repeat neuronal 3
Synonyms	FIGLER5,NLRR-3,NLRR3
General protein information	Preferred Names leucine rich repeat neuronal 3 Names leucine-rich repeat neuronal protein 3 fibronectin type III, immunoglobulin and leucine rich repeat domains 5 leucine-rich repeat protein, neuronal 3 neuronal leucine-rich repeat protein 3
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 7 Map Location: 7q31.1

mRNA and Protein(s)

mRNA	Protein	Name
NM_001099658.1	NP_001093128.1	leucine-rich repeat neuronal protein 3 precursor
NM_018334.5	NP_060804.3	leucine-rich repeat neuronal protein 3 precursor
NM_001099660.1	NP_001093130.1	leucine-rich repeat neuronal protein 3 precursor
NM_018334.4	NP_060804.3	leucine-rich repeat neuronal protein 3 precursor
NM_001099658.2	NP_001093128.1	leucine-rich repeat neuronal protein 3 precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	LRRN3	XP_527861.1
	LOC701932	XP_002808410.1
Canis lupus familiaris (dog)	LRRN3	XP_005628792.1
Mus musculus (house mouse)	Lrrn3	NP_001258637.1
Gallus gallus (chicken)	LRRN3	XP_001232594.1
Homo sapiens (human)	LRRN3	NP_001093128.1
Rattus norvegicus (Norway rat)	Lrrn3	NP_110483.1
Xenopus tropicalis (tropical clawed frog)	lrrn3	NP_001072526.1
Bos taurus (cattle)	LRRN3	XP_002686856.1
Danio rerio (zebrafish)	LOC100535105	XP_003201600.1

Gene Ontology
Bibliography

Related articles in PubMed

Intracellular fragment of NLRR3 (NLRR3-ICD) stimulates ATRA-dependent neuroblastoma differentiation.
Akter J, Takatori A, Islam MS, Nakazawa A, Ozaki T, Nagase H, Nakagawara A
Biochemical and biophysical research communications453(1)86-93(2014 Oct)

Expression of NLRR3 orphan receptor gene is negatively regulated by MYCN and Miz-1, and its downregulation is associated with unfavorable outcome in neuroblastoma.
Akter J, Takatori A, Hossain MS, Ozaki T, Nakazawa A, Ohira M, Suenaga Y, Nakagawara A
Clinical cancer research : an official journal of the American Association for Cancer Research17(21)6681-92(2011 Nov)

Polymorphisms in leucine-rich repeat genes are associated with autism spectrum disorder susceptibility in populations of European ancestry.
Sousa I, Clark TG, Holt R, Pagnamenta AT, Mulder EJ, Minderaa RB, Bailey AJ, Battaglia A, Klauck SM, Poustka F, Monaco AP,
Molecular autism1(1)7(2010 Mar)

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.
Clark HF, Gurney AL, Abaya E, Baker K, Baldwin D, Brush J, Chen J, Chow B, Chui C, Crowley C, Currell B, Deuel B, Dowd P, Eaton D, Foster J, Grimaldi C, Gu Q, Hass PE, Heldens S, Huang A, Kim HS, Klimowski L, Jin Y, Johnson S, Lee J, Lewis L, Liao D, Mark M, Robbie E, Sanchez C, Schoenfeld J, Seshagiri S, Simmons L, Singh J, Smith V, Stinson J, Vagts A, Vandlen R, Watanabe C, Wieand D, Woods K, Xie MH, Yansura D, Yi S, Yu G, Yuan J, Zhang M, Zhang Z, Goddard A, Wood WI, Godowski P, Gray A
Genome research13(10)2265-70(2003 Oct)

Rat neuronal leucine-rich repeat protein-3: cloning and regulation of the gene expression.
Fukamachi K, Matsuoka Y, Kitanaka C, Kuchino Y, Tsuda H
Biochemical and biophysical research communications287(1)257-63(2001 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

NLRR3 is proteolytically processed by secretases and its intracellular domain is then released to translocate into the cell nucleus during ATRA-mediated neuroblastoma differentiation.
Title: Intracellular fragment of NLRR3 (NLRR3-ICD) stimulates ATRA-dependent neuroblastoma differentiation.

NLRR3 is a direct target of MYCN, which associates with Miz-1 and negatively regulates NLRR3 expression. NLRR3 may play a role in NBL differentiation and the survival of NBL patients by inversely correlating with MYCN amplification.
Title: Expression of NLRR3 orphan receptor gene is negatively regulated by MYCN and Miz-1, and its downregulation is associated with unfavorable outcome in neuroblastoma.

Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.

Observational study of gene-disease association. (HuGE Navigator)
Title: Polymorphisms in leucine-rich repeat genes are associated with autism spectrum disorder susceptibility in populations of European ancestry.

The following LRRN3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LRRN3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu02442	NM_001099660.1 Latest version!	Homo sapiens leucine rich repeat neuronal 3 (LRRN3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu02442	NM_001099658.2 Latest version!	Homo sapiens leucine rich repeat neuronal 3 (LRRN3), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu02442	NM_018334.5 Latest version!	Homo sapiens leucine rich repeat neuronal 3 (LRRN3), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
View Old Accession Versions >>
OHu02442	NM_018334.4	Homo sapiens leucine rich repeat neuronal 3 (LRRN3), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu02442	NM_001099658.1	Homo sapiens leucine rich repeat neuronal 3 (LRRN3), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

LRRN3 ( NM_001099658.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001093128.1 Homo sapiens leucine rich repeat neuronal 3 (LRRN3), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu02442
Clone ID Related Accession (Same CDS sequence)	NM_001099658.1 , NM_018334.5 , NM_001099660.1 , NM_018334.4 , NM_001099658.2
Accession Version	NM_001099658.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2127bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	leucine-rich repeat neuronal protein 3 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA494543.1, AY358280.1, BC035133.2 and AL442092.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: SRR1803616.113513.1, SRR1803614.231411.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END##

ATGAAGGACA TGCCACTCCG AATTCATGTG CTACTTGGCC TAGCTATCAC TACACTAGTA 
CAAGCTGTAG ATAAAAAAGT GGATTGTCCA CGGTTATGTA CGTGTGAAAT CAGGCCTTGG 
TTTACACCCA GATCCATTTA TATGGAAGCA TCTACAGTGG ATTGTAATGA TTTAGGTCTT 
TTAACTTTCC CAGCCAGATT GCCAGCTAAC ACACAGATTC TTCTCCTACA GACTAACAAT 
ATTGCAAAAA TTGAATACTC CACAGACTTT CCAGTAAACC TTACTGGCCT GGATTTATCT 
CAAAACAATT TATCTTCAGT CACCAATATT AATGTAAAAA AGATGCCTCA GCTCCTTTCT 
GTGTACCTAG AGGAAAACAA ACTTACTGAA CTGCCTGAAA AATGTCTGTC CGAACTGAGC 
AACTTACAAG AACTCTATAT TAATCACAAC TTGCTTTCTA CAATTTCACC TGGAGCCTTT 
ATTGGCCTAC ATAATCTTCT TCGACTTCAT CTCAATTCAA ATAGATTGCA GATGATCAAC 
AGTAAGTGGT TTGATGCTCT TCCAAATCTA GAGATTCTGA TGATTGGGGA AAATCCAATT 
ATCAGAATCA AAGACATGAA CTTTAAGCCT CTTATCAATC TTCGCAGCCT GGTTATAGCT 
GGTATAAACC TCACAGAAAT ACCAGATAAC GCCTTGGTTG GACTGGAAAA CTTAGAAAGC 
ATCTCTTTTT ACGATAACAG GCTTATTAAA GTACCCCATG TTGCTCTTCA AAAAGTTGTA 
AATCTCAAAT TTTTGGATCT AAATAAAAAT CCTATTAATA GAATACGAAG GGGTGATTTT 
AGCAATATGC TACACTTAAA AGAGTTGGGG ATAAATAATA TGCCTGAGCT GATTTCCATC 
GATAGTCTTG CTGTGGATAA CCTGCCAGAT TTAAGAAAAA TAGAAGCTAC TAACAACCCT 
AGATTGTCTT ACATTCACCC CAATGCATTT TTCAGACTCC CCAAGCTGGA ATCACTCATG 
CTGAACAGCA ATGCTCTCAG TGCCCTGTAC CATGGTACCA TTGAGTCTCT GCCAAACCTC 
AAGGAAATCA GCATACACAG TAACCCCATC AGGTGTGACT GTGTCATCCG TTGGATGAAC 
ATGAACAAAA CCAACATTCG ATTCATGGAG CCAGATTCAC TGTTTTGCGT GGACCCACCT 
GAATTCCAAG GTCAGAATGT TCGGCAAGTG CATTTCAGGG ACATGATGGA AATTTGTCTC 
CCTCTTATAG CTCCTGAGAG CTTTCCTTCT AATCTAAATG TAGAAGCTGG GAGCTATGTT 
TCCTTTCACT GTAGAGCTAC TGCAGAACCA CAGCCTGAAA TCTACTGGAT AACACCTTCT 
GGTCAAAAAC TCTTGCCTAA TACCCTGACA GACAAGTTCT ATGTCCATTC TGAGGGAACA 
CTAGATATAA ATGGCGTAAC TCCCAAAGAA GGGGGTTTAT ATACTTGTAT AGCAACTAAC 
CTAGTTGGCG CTGACTTGAA GTCTGTTATG ATCAAAGTGG ATGGATCTTT TCCACAAGAT 
AACAATGGCT CTTTGAATAT TAAAATAAGA GATATTCAGG CCAATTCAGT TTTGGTGTCC 
TGGAAAGCAA GTTCTAAAAT TCTCAAATCT AGTGTTAAAT GGACAGCCTT TGTCAAGACT 
GAAAATTCTC ATGCTGCGCA AAGTGCTCGA ATACCATCTG ATGTCAAGGT ATATAATCTT 
ACTCATCTGA ATCCATCAAC TGAGTATAAA ATTTGTATTG ATATTCCCAC CATCTATCAG 
AAAAACAGAA AAAAATGTGT AAATGTCACC ACCAAAGGTT TGCACCCTGA TCAAAAAGAG 
TATGAAAAGA ATAATACCAC AACACTTATG GCCTGTCTTG GAGGCCTTCT GGGGATTATT 
GGTGTGATAT GTCTTATCAG CTGCCTCTCT CCAGAAATGA ACTGTGATGG TGGACACAGC 
TATGTGAGGA ATTACTTACA GAAACCAACC TTTGCATTAG GTGAGCTTTA TCCTCCTCTG 
ATAAATCTCT GGGAAGCAGG AAAAGAAAAA AGTACATCAC TGAAAGTAAA AGCAACTGTT 
ATAGGTTTAC CAACAAATAT GTCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001093128.1
CDS	940..3066
Translation	MKDMPLRIHVLLGLAITTLVQAVDKKVDCPRLCTCEIRPWFTPRSIYMEASTVDCNDLGLLTFPARLPANTQILLLQTNNIAKIEYSTDFPVNLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNMPELISIDSLAVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNLKEISIHSNPIRCDCVIRWMNMNKTNIRFMEPDSLFCVDPPEFQGQNVRQVHFRDMMEICLPLIAPESFPSNLNVEAGSYVSFHCRATAEPQPEIYWITPSGQKLLPNTLTDKFYVHSEGTLDINGVTPKEGGLYTCIATNLVGADLKSVMIKVDGSFPQDNNGSLNIKIRDIQANSVLVSWKASSKILKSSVKWTAFVKTENSHAAQSARIPSDVKVYNLTHLNPSTEYKICIDIPTIYQKNRKKCVNVTTKGLHPDQKEYEKNNTTTLMACLGGLLGIIGVICLISCLSPEMNCDGGHSYVRNYLQKPTFALGELYPPLINLWEAGKEKSTSLKVKATVIGLPTNMS

Target ORF information:

RefSeq Version	NM_001099658.1
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeat neuronal 3 (LRRN3), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001099658.1

ORF Insert Sequence:

ATGAAGGACA TGCCACTCCG AATTCATGTG CTACTTGGCC TAGCTATCAC TACACTAGTA 
CAAGCTGTAG ATAAAAAAGT GGATTGTCCA CGGTTATGTA CGTGTGAAAT CAGGCCTTGG 
TTTACACCCA GATCCATTTA TATGGAAGCA TCTACAGTGG ATTGTAATGA TTTAGGTCTT 
TTAACTTTCC CAGCCAGATT GCCAGCTAAC ACACAGATTC TTCTCCTACA GACTAACAAT 
ATTGCAAAAA TTGAATACTC CACAGACTTT CCAGTAAACC TTACTGGCCT GGATTTATCT 
CAAAACAATT TATCTTCAGT CACCAATATT AATGTAAAAA AGATGCCTCA GCTCCTTTCT 
GTGTACCTAG AGGAAAACAA ACTTACTGAA CTGCCTGAAA AATGTCTGTC CGAACTGAGC 
AACTTACAAG AACTCTATAT TAATCACAAC TTGCTTTCTA CAATTTCACC TGGAGCCTTT 
ATTGGCCTAC ATAATCTTCT TCGACTTCAT CTCAATTCAA ATAGATTGCA GATGATCAAC 
AGTAAGTGGT TTGATGCTCT TCCAAATCTA GAGATTCTGA TGATTGGGGA AAATCCAATT 
ATCAGAATCA AAGACATGAA CTTTAAGCCT CTTATCAATC TTCGCAGCCT GGTTATAGCT 
GGTATAAACC TCACAGAAAT ACCAGATAAC GCCTTGGTTG GACTGGAAAA CTTAGAAAGC 
ATCTCTTTTT ACGATAACAG GCTTATTAAA GTACCCCATG TTGCTCTTCA AAAAGTTGTA 
AATCTCAAAT TTTTGGATCT AAATAAAAAT CCTATTAATA GAATACGAAG GGGTGATTTT 
AGCAATATGC TACACTTAAA AGAGTTGGGG ATAAATAATA TGCCTGAGCT GATTTCCATC 
GATAGTCTTG CTGTGGATAA CCTGCCAGAT TTAAGAAAAA TAGAAGCTAC TAACAACCCT 
AGATTGTCTT ACATTCACCC CAATGCATTT TTCAGACTCC CCAAGCTGGA ATCACTCATG 
CTGAACAGCA ATGCTCTCAG TGCCCTGTAC CATGGTACCA TTGAGTCTCT GCCAAACCTC 
AAGGAAATCA GCATACACAG TAACCCCATC AGGTGTGACT GTGTCATCCG TTGGATGAAC 
ATGAACAAAA CCAACATTCG ATTCATGGAG CCAGATTCAC TGTTTTGCGT GGACCCACCT 
GAATTCCAAG GTCAGAATGT TCGGCAAGTG CATTTCAGGG ACATGATGGA AATTTGTCTC 
CCTCTTATAG CTCCTGAGAG CTTTCCTTCT AATCTAAATG TAGAAGCTGG GAGCTATGTT 
TCCTTTCACT GTAGAGCTAC TGCAGAACCA CAGCCTGAAA TCTACTGGAT AACACCTTCT 
GGTCAAAAAC TCTTGCCTAA TACCCTGACA GACAAGTTCT ATGTCCATTC TGAGGGAACA 
CTAGATATAA ATGGCGTAAC TCCCAAAGAA GGGGGTTTAT ATACTTGTAT AGCAACTAAC 
CTAGTTGGCG CTGACTTGAA GTCTGTTATG ATCAAAGTGG ATGGATCTTT TCCACAAGAT 
AACAATGGCT CTTTGAATAT TAAAATAAGA GATATTCAGG CCAATTCAGT TTTGGTGTCC 
TGGAAAGCAA GTTCTAAAAT TCTCAAATCT AGTGTTAAAT GGACAGCCTT TGTCAAGACT 
GAAAATTCTC ATGCTGCGCA AAGTGCTCGA ATACCATCTG ATGTCAAGGT ATATAATCTT 
ACTCATCTGA ATCCATCAAC TGAGTATAAA ATTTGTATTG ATATTCCCAC CATCTATCAG 
AAAAACAGAA AAAAATGTGT AAATGTCACC ACCAAAGGTT TGCACCCTGA TCAAAAAGAG 
TATGAAAAGA ATAATACCAC AACACTTATG GCCTGTCTTG GAGGCCTTCT GGGGATTATT 
GGTGTGATAT GTCTTATCAG CTGCCTCTCT CCAGAAATGA ACTGTGATGG TGGACACAGC 
TATGTGAGGA ATTACTTACA GAAACCAACC TTTGCATTAG GTGAGCTTTA TCCTCCTCTG 
ATAAATCTCT GGGAAGCAGG AAAAGAAAAA AGTACATCAC TGAAAGTAAA AGCAACTGTT 
ATAGGTTTAC CAACAAATAT GTCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRRN3 ( NM_018334.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_060804.3 Homo sapiens leucine rich repeat neuronal 3 (LRRN3), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu02442
Clone ID Related Accession (Same CDS sequence)	NM_001099658.1 , NM_018334.5 , NM_001099660.1 , NM_018334.4 , NM_001099658.2
Accession Version	NM_018334.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2127bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-30
Organism	Homo sapiens(human)
Product	leucine-rich repeat neuronal protein 3 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA494543.1, DB095402.1, AF134481.1 and AL442092.1. On May 31, 2019 this sequence version replaced NM_018334.4. Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: BC035133.2, SRR1660807.125888.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968832, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END##

ATGAAGGACA TGCCACTCCG AATTCATGTG CTACTTGGCC TAGCTATCAC TACACTAGTA 
CAAGCTGTAG ATAAAAAAGT GGATTGTCCA CGGTTATGTA CGTGTGAAAT CAGGCCTTGG 
TTTACACCCA GATCCATTTA TATGGAAGCA TCTACAGTGG ATTGTAATGA TTTAGGTCTT 
TTAACTTTCC CAGCCAGATT GCCAGCTAAC ACACAGATTC TTCTCCTACA GACTAACAAT 
ATTGCAAAAA TTGAATACTC CACAGACTTT CCAGTAAACC TTACTGGCCT GGATTTATCT 
CAAAACAATT TATCTTCAGT CACCAATATT AATGTAAAAA AGATGCCTCA GCTCCTTTCT 
GTGTACCTAG AGGAAAACAA ACTTACTGAA CTGCCTGAAA AATGTCTGTC CGAACTGAGC 
AACTTACAAG AACTCTATAT TAATCACAAC TTGCTTTCTA CAATTTCACC TGGAGCCTTT 
ATTGGCCTAC ATAATCTTCT TCGACTTCAT CTCAATTCAA ATAGATTGCA GATGATCAAC 
AGTAAGTGGT TTGATGCTCT TCCAAATCTA GAGATTCTGA TGATTGGGGA AAATCCAATT 
ATCAGAATCA AAGACATGAA CTTTAAGCCT CTTATCAATC TTCGCAGCCT GGTTATAGCT 
GGTATAAACC TCACAGAAAT ACCAGATAAC GCCTTGGTTG GACTGGAAAA CTTAGAAAGC 
ATCTCTTTTT ACGATAACAG GCTTATTAAA GTACCCCATG TTGCTCTTCA AAAAGTTGTA 
AATCTCAAAT TTTTGGATCT AAATAAAAAT CCTATTAATA GAATACGAAG GGGTGATTTT 
AGCAATATGC TACACTTAAA AGAGTTGGGG ATAAATAATA TGCCTGAGCT GATTTCCATC 
GATAGTCTTG CTGTGGATAA CCTGCCAGAT TTAAGAAAAA TAGAAGCTAC TAACAACCCT 
AGATTGTCTT ACATTCACCC CAATGCATTT TTCAGACTCC CCAAGCTGGA ATCACTCATG 
CTGAACAGCA ATGCTCTCAG TGCCCTGTAC CATGGTACCA TTGAGTCTCT GCCAAACCTC 
AAGGAAATCA GCATACACAG TAACCCCATC AGGTGTGACT GTGTCATCCG TTGGATGAAC 
ATGAACAAAA CCAACATTCG ATTCATGGAG CCAGATTCAC TGTTTTGCGT GGACCCACCT 
GAATTCCAAG GTCAGAATGT TCGGCAAGTG CATTTCAGGG ACATGATGGA AATTTGTCTC 
CCTCTTATAG CTCCTGAGAG CTTTCCTTCT AATCTAAATG TAGAAGCTGG GAGCTATGTT 
TCCTTTCACT GTAGAGCTAC TGCAGAACCA CAGCCTGAAA TCTACTGGAT AACACCTTCT 
GGTCAAAAAC TCTTGCCTAA TACCCTGACA GACAAGTTCT ATGTCCATTC TGAGGGAACA 
CTAGATATAA ATGGCGTAAC TCCCAAAGAA GGGGGTTTAT ATACTTGTAT AGCAACTAAC 
CTAGTTGGCG CTGACTTGAA GTCTGTTATG ATCAAAGTGG ATGGATCTTT TCCACAAGAT 
AACAATGGCT CTTTGAATAT TAAAATAAGA GATATTCAGG CCAATTCAGT TTTGGTGTCC 
TGGAAAGCAA GTTCTAAAAT TCTCAAATCT AGTGTTAAAT GGACAGCCTT TGTCAAGACT 
GAAAATTCTC ATGCTGCGCA AAGTGCTCGA ATACCATCTG ATGTCAAGGT ATATAATCTT 
ACTCATCTGA ATCCATCAAC TGAGTATAAA ATTTGTATTG ATATTCCCAC CATCTATCAG 
AAAAACAGAA AAAAATGTGT AAATGTCACC ACCAAAGGTT TGCACCCTGA TCAAAAAGAG 
TATGAAAAGA ATAATACCAC AACACTTATG GCCTGTCTTG GAGGCCTTCT GGGGATTATT 
GGTGTGATAT GTCTTATCAG CTGCCTCTCT CCAGAAATGA ACTGTGATGG TGGACACAGC 
TATGTGAGGA ATTACTTACA GAAACCAACC TTTGCATTAG GTGAGCTTTA TCCTCCTCTG 
ATAAATCTCT GGGAAGCAGG AAAAGAAAAA AGTACATCAC TGAAAGTAAA AGCAACTGTT 
ATAGGTTTAC CAACAAATAT GTCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060804.3
CDS	737..2863
Translation	MKDMPLRIHVLLGLAITTLVQAVDKKVDCPRLCTCEIRPWFTPRSIYMEASTVDCNDLGLLTFPARLPANTQILLLQTNNIAKIEYSTDFPVNLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNMPELISIDSLAVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNLKEISIHSNPIRCDCVIRWMNMNKTNIRFMEPDSLFCVDPPEFQGQNVRQVHFRDMMEICLPLIAPESFPSNLNVEAGSYVSFHCRATAEPQPEIYWITPSGQKLLPNTLTDKFYVHSEGTLDINGVTPKEGGLYTCIATNLVGADLKSVMIKVDGSFPQDNNGSLNIKIRDIQANSVLVSWKASSKILKSSVKWTAFVKTENSHAAQSARIPSDVKVYNLTHLNPSTEYKICIDIPTIYQKNRKKCVNVTTKGLHPDQKEYEKNNTTTLMACLGGLLGIIGVICLISCLSPEMNCDGGHSYVRNYLQKPTFALGELYPPLINLWEAGKEKSTSLKVKATVIGLPTNMS

Target ORF information:

RefSeq Version	NM_018334.5
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeat neuronal 3 (LRRN3), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018334.5

ORF Insert Sequence:

ATGAAGGACA TGCCACTCCG AATTCATGTG CTACTTGGCC TAGCTATCAC TACACTAGTA 
CAAGCTGTAG ATAAAAAAGT GGATTGTCCA CGGTTATGTA CGTGTGAAAT CAGGCCTTGG 
TTTACACCCA GATCCATTTA TATGGAAGCA TCTACAGTGG ATTGTAATGA TTTAGGTCTT 
TTAACTTTCC CAGCCAGATT GCCAGCTAAC ACACAGATTC TTCTCCTACA GACTAACAAT 
ATTGCAAAAA TTGAATACTC CACAGACTTT CCAGTAAACC TTACTGGCCT GGATTTATCT 
CAAAACAATT TATCTTCAGT CACCAATATT AATGTAAAAA AGATGCCTCA GCTCCTTTCT 
GTGTACCTAG AGGAAAACAA ACTTACTGAA CTGCCTGAAA AATGTCTGTC CGAACTGAGC 
AACTTACAAG AACTCTATAT TAATCACAAC TTGCTTTCTA CAATTTCACC TGGAGCCTTT 
ATTGGCCTAC ATAATCTTCT TCGACTTCAT CTCAATTCAA ATAGATTGCA GATGATCAAC 
AGTAAGTGGT TTGATGCTCT TCCAAATCTA GAGATTCTGA TGATTGGGGA AAATCCAATT 
ATCAGAATCA AAGACATGAA CTTTAAGCCT CTTATCAATC TTCGCAGCCT GGTTATAGCT 
GGTATAAACC TCACAGAAAT ACCAGATAAC GCCTTGGTTG GACTGGAAAA CTTAGAAAGC 
ATCTCTTTTT ACGATAACAG GCTTATTAAA GTACCCCATG TTGCTCTTCA AAAAGTTGTA 
AATCTCAAAT TTTTGGATCT AAATAAAAAT CCTATTAATA GAATACGAAG GGGTGATTTT 
AGCAATATGC TACACTTAAA AGAGTTGGGG ATAAATAATA TGCCTGAGCT GATTTCCATC 
GATAGTCTTG CTGTGGATAA CCTGCCAGAT TTAAGAAAAA TAGAAGCTAC TAACAACCCT 
AGATTGTCTT ACATTCACCC CAATGCATTT TTCAGACTCC CCAAGCTGGA ATCACTCATG 
CTGAACAGCA ATGCTCTCAG TGCCCTGTAC CATGGTACCA TTGAGTCTCT GCCAAACCTC 
AAGGAAATCA GCATACACAG TAACCCCATC AGGTGTGACT GTGTCATCCG TTGGATGAAC 
ATGAACAAAA CCAACATTCG ATTCATGGAG CCAGATTCAC TGTTTTGCGT GGACCCACCT 
GAATTCCAAG GTCAGAATGT TCGGCAAGTG CATTTCAGGG ACATGATGGA AATTTGTCTC 
CCTCTTATAG CTCCTGAGAG CTTTCCTTCT AATCTAAATG TAGAAGCTGG GAGCTATGTT 
TCCTTTCACT GTAGAGCTAC TGCAGAACCA CAGCCTGAAA TCTACTGGAT AACACCTTCT 
GGTCAAAAAC TCTTGCCTAA TACCCTGACA GACAAGTTCT ATGTCCATTC TGAGGGAACA 
CTAGATATAA ATGGCGTAAC TCCCAAAGAA GGGGGTTTAT ATACTTGTAT AGCAACTAAC 
CTAGTTGGCG CTGACTTGAA GTCTGTTATG ATCAAAGTGG ATGGATCTTT TCCACAAGAT 
AACAATGGCT CTTTGAATAT TAAAATAAGA GATATTCAGG CCAATTCAGT TTTGGTGTCC 
TGGAAAGCAA GTTCTAAAAT TCTCAAATCT AGTGTTAAAT GGACAGCCTT TGTCAAGACT 
GAAAATTCTC ATGCTGCGCA AAGTGCTCGA ATACCATCTG ATGTCAAGGT ATATAATCTT 
ACTCATCTGA ATCCATCAAC TGAGTATAAA ATTTGTATTG ATATTCCCAC CATCTATCAG 
AAAAACAGAA AAAAATGTGT AAATGTCACC ACCAAAGGTT TGCACCCTGA TCAAAAAGAG 
TATGAAAAGA ATAATACCAC AACACTTATG GCCTGTCTTG GAGGCCTTCT GGGGATTATT 
GGTGTGATAT GTCTTATCAG CTGCCTCTCT CCAGAAATGA ACTGTGATGG TGGACACAGC 
TATGTGAGGA ATTACTTACA GAAACCAACC TTTGCATTAG GTGAGCTTTA TCCTCCTCTG 
ATAAATCTCT GGGAAGCAGG AAAAGAAAAA AGTACATCAC TGAAAGTAAA AGCAACTGTT 
ATAGGTTTAC CAACAAATAT GTCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRRN3 ( NM_001099660.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001093130.1 Homo sapiens leucine rich repeat neuronal 3 (LRRN3), transcript variant 1, mRNA.

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CloneID	OHu02442
Clone ID Related Accession (Same CDS sequence)	NM_001099658.1 , NM_018334.5 , NM_001099660.1 , NM_018334.4 , NM_001099658.2
Accession Version	NM_001099660.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2127bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-20
Organism	Homo sapiens(human)
Product	leucine-rich repeat neuronal protein 3 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA494543.1, AK001991.1, AY358280.1, BC035133.2 and AL442092.1. Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2 and 3 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.13317.1, SRR1660805.203671.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END##

ATGAAGGACA TGCCACTCCG AATTCATGTG CTACTTGGCC TAGCTATCAC TACACTAGTA 
CAAGCTGTAG ATAAAAAAGT GGATTGTCCA CGGTTATGTA CGTGTGAAAT CAGGCCTTGG 
TTTACACCCA GATCCATTTA TATGGAAGCA TCTACAGTGG ATTGTAATGA TTTAGGTCTT 
TTAACTTTCC CAGCCAGATT GCCAGCTAAC ACACAGATTC TTCTCCTACA GACTAACAAT 
ATTGCAAAAA TTGAATACTC CACAGACTTT CCAGTAAACC TTACTGGCCT GGATTTATCT 
CAAAACAATT TATCTTCAGT CACCAATATT AATGTAAAAA AGATGCCTCA GCTCCTTTCT 
GTGTACCTAG AGGAAAACAA ACTTACTGAA CTGCCTGAAA AATGTCTGTC CGAACTGAGC 
AACTTACAAG AACTCTATAT TAATCACAAC TTGCTTTCTA CAATTTCACC TGGAGCCTTT 
ATTGGCCTAC ATAATCTTCT TCGACTTCAT CTCAATTCAA ATAGATTGCA GATGATCAAC 
AGTAAGTGGT TTGATGCTCT TCCAAATCTA GAGATTCTGA TGATTGGGGA AAATCCAATT 
ATCAGAATCA AAGACATGAA CTTTAAGCCT CTTATCAATC TTCGCAGCCT GGTTATAGCT 
GGTATAAACC TCACAGAAAT ACCAGATAAC GCCTTGGTTG GACTGGAAAA CTTAGAAAGC 
ATCTCTTTTT ACGATAACAG GCTTATTAAA GTACCCCATG TTGCTCTTCA AAAAGTTGTA 
AATCTCAAAT TTTTGGATCT AAATAAAAAT CCTATTAATA GAATACGAAG GGGTGATTTT 
AGCAATATGC TACACTTAAA AGAGTTGGGG ATAAATAATA TGCCTGAGCT GATTTCCATC 
GATAGTCTTG CTGTGGATAA CCTGCCAGAT TTAAGAAAAA TAGAAGCTAC TAACAACCCT 
AGATTGTCTT ACATTCACCC CAATGCATTT TTCAGACTCC CCAAGCTGGA ATCACTCATG 
CTGAACAGCA ATGCTCTCAG TGCCCTGTAC CATGGTACCA TTGAGTCTCT GCCAAACCTC 
AAGGAAATCA GCATACACAG TAACCCCATC AGGTGTGACT GTGTCATCCG TTGGATGAAC 
ATGAACAAAA CCAACATTCG ATTCATGGAG CCAGATTCAC TGTTTTGCGT GGACCCACCT 
GAATTCCAAG GTCAGAATGT TCGGCAAGTG CATTTCAGGG ACATGATGGA AATTTGTCTC 
CCTCTTATAG CTCCTGAGAG CTTTCCTTCT AATCTAAATG TAGAAGCTGG GAGCTATGTT 
TCCTTTCACT GTAGAGCTAC TGCAGAACCA CAGCCTGAAA TCTACTGGAT AACACCTTCT 
GGTCAAAAAC TCTTGCCTAA TACCCTGACA GACAAGTTCT ATGTCCATTC TGAGGGAACA 
CTAGATATAA ATGGCGTAAC TCCCAAAGAA GGGGGTTTAT ATACTTGTAT AGCAACTAAC 
CTAGTTGGCG CTGACTTGAA GTCTGTTATG ATCAAAGTGG ATGGATCTTT TCCACAAGAT 
AACAATGGCT CTTTGAATAT TAAAATAAGA GATATTCAGG CCAATTCAGT TTTGGTGTCC 
TGGAAAGCAA GTTCTAAAAT TCTCAAATCT AGTGTTAAAT GGACAGCCTT TGTCAAGACT 
GAAAATTCTC ATGCTGCGCA AAGTGCTCGA ATACCATCTG ATGTCAAGGT ATATAATCTT 
ACTCATCTGA ATCCATCAAC TGAGTATAAA ATTTGTATTG ATATTCCCAC CATCTATCAG 
AAAAACAGAA AAAAATGTGT AAATGTCACC ACCAAAGGTT TGCACCCTGA TCAAAAAGAG 
TATGAAAAGA ATAATACCAC AACACTTATG GCCTGTCTTG GAGGCCTTCT GGGGATTATT 
GGTGTGATAT GTCTTATCAG CTGCCTCTCT CCAGAAATGA ACTGTGATGG TGGACACAGC 
TATGTGAGGA ATTACTTACA GAAACCAACC TTTGCATTAG GTGAGCTTTA TCCTCCTCTG 
ATAAATCTCT GGGAAGCAGG AAAAGAAAAA AGTACATCAC TGAAAGTAAA AGCAACTGTT 
ATAGGTTTAC CAACAAATAT GTCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001093130.1
CDS	1047..3173
Translation	MKDMPLRIHVLLGLAITTLVQAVDKKVDCPRLCTCEIRPWFTPRSIYMEASTVDCNDLGLLTFPARLPANTQILLLQTNNIAKIEYSTDFPVNLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNMPELISIDSLAVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNLKEISIHSNPIRCDCVIRWMNMNKTNIRFMEPDSLFCVDPPEFQGQNVRQVHFRDMMEICLPLIAPESFPSNLNVEAGSYVSFHCRATAEPQPEIYWITPSGQKLLPNTLTDKFYVHSEGTLDINGVTPKEGGLYTCIATNLVGADLKSVMIKVDGSFPQDNNGSLNIKIRDIQANSVLVSWKASSKILKSSVKWTAFVKTENSHAAQSARIPSDVKVYNLTHLNPSTEYKICIDIPTIYQKNRKKCVNVTTKGLHPDQKEYEKNNTTTLMACLGGLLGIIGVICLISCLSPEMNCDGGHSYVRNYLQKPTFALGELYPPLINLWEAGKEKSTSLKVKATVIGLPTNMS

Target ORF information:

RefSeq Version	NM_001099660.1
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeat neuronal 3 (LRRN3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001099660.1

ORF Insert Sequence:

ATGAAGGACA TGCCACTCCG AATTCATGTG CTACTTGGCC TAGCTATCAC TACACTAGTA 
CAAGCTGTAG ATAAAAAAGT GGATTGTCCA CGGTTATGTA CGTGTGAAAT CAGGCCTTGG 
TTTACACCCA GATCCATTTA TATGGAAGCA TCTACAGTGG ATTGTAATGA TTTAGGTCTT 
TTAACTTTCC CAGCCAGATT GCCAGCTAAC ACACAGATTC TTCTCCTACA GACTAACAAT 
ATTGCAAAAA TTGAATACTC CACAGACTTT CCAGTAAACC TTACTGGCCT GGATTTATCT 
CAAAACAATT TATCTTCAGT CACCAATATT AATGTAAAAA AGATGCCTCA GCTCCTTTCT 
GTGTACCTAG AGGAAAACAA ACTTACTGAA CTGCCTGAAA AATGTCTGTC CGAACTGAGC 
AACTTACAAG AACTCTATAT TAATCACAAC TTGCTTTCTA CAATTTCACC TGGAGCCTTT 
ATTGGCCTAC ATAATCTTCT TCGACTTCAT CTCAATTCAA ATAGATTGCA GATGATCAAC 
AGTAAGTGGT TTGATGCTCT TCCAAATCTA GAGATTCTGA TGATTGGGGA AAATCCAATT 
ATCAGAATCA AAGACATGAA CTTTAAGCCT CTTATCAATC TTCGCAGCCT GGTTATAGCT 
GGTATAAACC TCACAGAAAT ACCAGATAAC GCCTTGGTTG GACTGGAAAA CTTAGAAAGC 
ATCTCTTTTT ACGATAACAG GCTTATTAAA GTACCCCATG TTGCTCTTCA AAAAGTTGTA 
AATCTCAAAT TTTTGGATCT AAATAAAAAT CCTATTAATA GAATACGAAG GGGTGATTTT 
AGCAATATGC TACACTTAAA AGAGTTGGGG ATAAATAATA TGCCTGAGCT GATTTCCATC 
GATAGTCTTG CTGTGGATAA CCTGCCAGAT TTAAGAAAAA TAGAAGCTAC TAACAACCCT 
AGATTGTCTT ACATTCACCC CAATGCATTT TTCAGACTCC CCAAGCTGGA ATCACTCATG 
CTGAACAGCA ATGCTCTCAG TGCCCTGTAC CATGGTACCA TTGAGTCTCT GCCAAACCTC 
AAGGAAATCA GCATACACAG TAACCCCATC AGGTGTGACT GTGTCATCCG TTGGATGAAC 
ATGAACAAAA CCAACATTCG ATTCATGGAG CCAGATTCAC TGTTTTGCGT GGACCCACCT 
GAATTCCAAG GTCAGAATGT TCGGCAAGTG CATTTCAGGG ACATGATGGA AATTTGTCTC 
CCTCTTATAG CTCCTGAGAG CTTTCCTTCT AATCTAAATG TAGAAGCTGG GAGCTATGTT 
TCCTTTCACT GTAGAGCTAC TGCAGAACCA CAGCCTGAAA TCTACTGGAT AACACCTTCT 
GGTCAAAAAC TCTTGCCTAA TACCCTGACA GACAAGTTCT ATGTCCATTC TGAGGGAACA 
CTAGATATAA ATGGCGTAAC TCCCAAAGAA GGGGGTTTAT ATACTTGTAT AGCAACTAAC 
CTAGTTGGCG CTGACTTGAA GTCTGTTATG ATCAAAGTGG ATGGATCTTT TCCACAAGAT 
AACAATGGCT CTTTGAATAT TAAAATAAGA GATATTCAGG CCAATTCAGT TTTGGTGTCC 
TGGAAAGCAA GTTCTAAAAT TCTCAAATCT AGTGTTAAAT GGACAGCCTT TGTCAAGACT 
GAAAATTCTC ATGCTGCGCA AAGTGCTCGA ATACCATCTG ATGTCAAGGT ATATAATCTT 
ACTCATCTGA ATCCATCAAC TGAGTATAAA ATTTGTATTG ATATTCCCAC CATCTATCAG 
AAAAACAGAA AAAAATGTGT AAATGTCACC ACCAAAGGTT TGCACCCTGA TCAAAAAGAG 
TATGAAAAGA ATAATACCAC AACACTTATG GCCTGTCTTG GAGGCCTTCT GGGGATTATT 
GGTGTGATAT GTCTTATCAG CTGCCTCTCT CCAGAAATGA ACTGTGATGG TGGACACAGC 
TATGTGAGGA ATTACTTACA GAAACCAACC TTTGCATTAG GTGAGCTTTA TCCTCCTCTG 
ATAAATCTCT GGGAAGCAGG AAAAGAAAAA AGTACATCAC TGAAAGTAAA AGCAACTGTT 
ATAGGTTTAC CAACAAATAT GTCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRRN3 ( NM_018334.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_060804.3 Homo sapiens leucine rich repeat neuronal 3 (LRRN3), transcript variant 3, mRNA.

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CloneID	OHu02442
Clone ID Related Accession (Same CDS sequence)	NM_001099658.1 , NM_018334.5 , NM_001099660.1 , NM_018334.4 , NM_001099658.2
Accession Version	NM_018334.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2127bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-17
Organism	Homo sapiens(human)
Product	leucine-rich repeat neuronal protein 3 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA494543.1, DB095402.1, AF134481.1 and AL442092.1. On Jul 25, 2007 this sequence version replaced NM_018334.3. Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.105296.1, SRR1803613.257041.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968832, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END##

ATGAAGGACA TGCCACTCCG AATTCATGTG CTACTTGGCC TAGCTATCAC TACACTAGTA 
CAAGCTGTAG ATAAAAAAGT GGATTGTCCA CGGTTATGTA CGTGTGAAAT CAGGCCTTGG 
TTTACACCCA GATCCATTTA TATGGAAGCA TCTACAGTGG ATTGTAATGA TTTAGGTCTT 
TTAACTTTCC CAGCCAGATT GCCAGCTAAC ACACAGATTC TTCTCCTACA GACTAACAAT 
ATTGCAAAAA TTGAATACTC CACAGACTTT CCAGTAAACC TTACTGGCCT GGATTTATCT 
CAAAACAATT TATCTTCAGT CACCAATATT AATGTAAAAA AGATGCCTCA GCTCCTTTCT 
GTGTACCTAG AGGAAAACAA ACTTACTGAA CTGCCTGAAA AATGTCTGTC CGAACTGAGC 
AACTTACAAG AACTCTATAT TAATCACAAC TTGCTTTCTA CAATTTCACC TGGAGCCTTT 
ATTGGCCTAC ATAATCTTCT TCGACTTCAT CTCAATTCAA ATAGATTGCA GATGATCAAC 
AGTAAGTGGT TTGATGCTCT TCCAAATCTA GAGATTCTGA TGATTGGGGA AAATCCAATT 
ATCAGAATCA AAGACATGAA CTTTAAGCCT CTTATCAATC TTCGCAGCCT GGTTATAGCT 
GGTATAAACC TCACAGAAAT ACCAGATAAC GCCTTGGTTG GACTGGAAAA CTTAGAAAGC 
ATCTCTTTTT ACGATAACAG GCTTATTAAA GTACCCCATG TTGCTCTTCA AAAAGTTGTA 
AATCTCAAAT TTTTGGATCT AAATAAAAAT CCTATTAATA GAATACGAAG GGGTGATTTT 
AGCAATATGC TACACTTAAA AGAGTTGGGG ATAAATAATA TGCCTGAGCT GATTTCCATC 
GATAGTCTTG CTGTGGATAA CCTGCCAGAT TTAAGAAAAA TAGAAGCTAC TAACAACCCT 
AGATTGTCTT ACATTCACCC CAATGCATTT TTCAGACTCC CCAAGCTGGA ATCACTCATG 
CTGAACAGCA ATGCTCTCAG TGCCCTGTAC CATGGTACCA TTGAGTCTCT GCCAAACCTC 
AAGGAAATCA GCATACACAG TAACCCCATC AGGTGTGACT GTGTCATCCG TTGGATGAAC 
ATGAACAAAA CCAACATTCG ATTCATGGAG CCAGATTCAC TGTTTTGCGT GGACCCACCT 
GAATTCCAAG GTCAGAATGT TCGGCAAGTG CATTTCAGGG ACATGATGGA AATTTGTCTC 
CCTCTTATAG CTCCTGAGAG CTTTCCTTCT AATCTAAATG TAGAAGCTGG GAGCTATGTT 
TCCTTTCACT GTAGAGCTAC TGCAGAACCA CAGCCTGAAA TCTACTGGAT AACACCTTCT 
GGTCAAAAAC TCTTGCCTAA TACCCTGACA GACAAGTTCT ATGTCCATTC TGAGGGAACA 
CTAGATATAA ATGGCGTAAC TCCCAAAGAA GGGGGTTTAT ATACTTGTAT AGCAACTAAC 
CTAGTTGGCG CTGACTTGAA GTCTGTTATG ATCAAAGTGG ATGGATCTTT TCCACAAGAT 
AACAATGGCT CTTTGAATAT TAAAATAAGA GATATTCAGG CCAATTCAGT TTTGGTGTCC 
TGGAAAGCAA GTTCTAAAAT TCTCAAATCT AGTGTTAAAT GGACAGCCTT TGTCAAGACT 
GAAAATTCTC ATGCTGCGCA AAGTGCTCGA ATACCATCTG ATGTCAAGGT ATATAATCTT 
ACTCATCTGA ATCCATCAAC TGAGTATAAA ATTTGTATTG ATATTCCCAC CATCTATCAG 
AAAAACAGAA AAAAATGTGT AAATGTCACC ACCAAAGGTT TGCACCCTGA TCAAAAAGAG 
TATGAAAAGA ATAATACCAC AACACTTATG GCCTGTCTTG GAGGCCTTCT GGGGATTATT 
GGTGTGATAT GTCTTATCAG CTGCCTCTCT CCAGAAATGA ACTGTGATGG TGGACACAGC 
TATGTGAGGA ATTACTTACA GAAACCAACC TTTGCATTAG GTGAGCTTTA TCCTCCTCTG 
ATAAATCTCT GGGAAGCAGG AAAAGAAAAA AGTACATCAC TGAAAGTAAA AGCAACTGTT 
ATAGGTTTAC CAACAAATAT GTCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060804.3
CDS	858..2984
Translation	MKDMPLRIHVLLGLAITTLVQAVDKKVDCPRLCTCEIRPWFTPRSIYMEASTVDCNDLGLLTFPARLPANTQILLLQTNNIAKIEYSTDFPVNLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNMPELISIDSLAVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNLKEISIHSNPIRCDCVIRWMNMNKTNIRFMEPDSLFCVDPPEFQGQNVRQVHFRDMMEICLPLIAPESFPSNLNVEAGSYVSFHCRATAEPQPEIYWITPSGQKLLPNTLTDKFYVHSEGTLDINGVTPKEGGLYTCIATNLVGADLKSVMIKVDGSFPQDNNGSLNIKIRDIQANSVLVSWKASSKILKSSVKWTAFVKTENSHAAQSARIPSDVKVYNLTHLNPSTEYKICIDIPTIYQKNRKKCVNVTTKGLHPDQKEYEKNNTTTLMACLGGLLGIIGVICLISCLSPEMNCDGGHSYVRNYLQKPTFALGELYPPLINLWEAGKEKSTSLKVKATVIGLPTNMS

Target ORF information:

RefSeq Version	NM_018334.4
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeat neuronal 3 (LRRN3), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018334.4

ORF Insert Sequence:

ATGAAGGACA TGCCACTCCG AATTCATGTG CTACTTGGCC TAGCTATCAC TACACTAGTA 
CAAGCTGTAG ATAAAAAAGT GGATTGTCCA CGGTTATGTA CGTGTGAAAT CAGGCCTTGG 
TTTACACCCA GATCCATTTA TATGGAAGCA TCTACAGTGG ATTGTAATGA TTTAGGTCTT 
TTAACTTTCC CAGCCAGATT GCCAGCTAAC ACACAGATTC TTCTCCTACA GACTAACAAT 
ATTGCAAAAA TTGAATACTC CACAGACTTT CCAGTAAACC TTACTGGCCT GGATTTATCT 
CAAAACAATT TATCTTCAGT CACCAATATT AATGTAAAAA AGATGCCTCA GCTCCTTTCT 
GTGTACCTAG AGGAAAACAA ACTTACTGAA CTGCCTGAAA AATGTCTGTC CGAACTGAGC 
AACTTACAAG AACTCTATAT TAATCACAAC TTGCTTTCTA CAATTTCACC TGGAGCCTTT 
ATTGGCCTAC ATAATCTTCT TCGACTTCAT CTCAATTCAA ATAGATTGCA GATGATCAAC 
AGTAAGTGGT TTGATGCTCT TCCAAATCTA GAGATTCTGA TGATTGGGGA AAATCCAATT 
ATCAGAATCA AAGACATGAA CTTTAAGCCT CTTATCAATC TTCGCAGCCT GGTTATAGCT 
GGTATAAACC TCACAGAAAT ACCAGATAAC GCCTTGGTTG GACTGGAAAA CTTAGAAAGC 
ATCTCTTTTT ACGATAACAG GCTTATTAAA GTACCCCATG TTGCTCTTCA AAAAGTTGTA 
AATCTCAAAT TTTTGGATCT AAATAAAAAT CCTATTAATA GAATACGAAG GGGTGATTTT 
AGCAATATGC TACACTTAAA AGAGTTGGGG ATAAATAATA TGCCTGAGCT GATTTCCATC 
GATAGTCTTG CTGTGGATAA CCTGCCAGAT TTAAGAAAAA TAGAAGCTAC TAACAACCCT 
AGATTGTCTT ACATTCACCC CAATGCATTT TTCAGACTCC CCAAGCTGGA ATCACTCATG 
CTGAACAGCA ATGCTCTCAG TGCCCTGTAC CATGGTACCA TTGAGTCTCT GCCAAACCTC 
AAGGAAATCA GCATACACAG TAACCCCATC AGGTGTGACT GTGTCATCCG TTGGATGAAC 
ATGAACAAAA CCAACATTCG ATTCATGGAG CCAGATTCAC TGTTTTGCGT GGACCCACCT 
GAATTCCAAG GTCAGAATGT TCGGCAAGTG CATTTCAGGG ACATGATGGA AATTTGTCTC 
CCTCTTATAG CTCCTGAGAG CTTTCCTTCT AATCTAAATG TAGAAGCTGG GAGCTATGTT 
TCCTTTCACT GTAGAGCTAC TGCAGAACCA CAGCCTGAAA TCTACTGGAT AACACCTTCT 
GGTCAAAAAC TCTTGCCTAA TACCCTGACA GACAAGTTCT ATGTCCATTC TGAGGGAACA 
CTAGATATAA ATGGCGTAAC TCCCAAAGAA GGGGGTTTAT ATACTTGTAT AGCAACTAAC 
CTAGTTGGCG CTGACTTGAA GTCTGTTATG ATCAAAGTGG ATGGATCTTT TCCACAAGAT 
AACAATGGCT CTTTGAATAT TAAAATAAGA GATATTCAGG CCAATTCAGT TTTGGTGTCC 
TGGAAAGCAA GTTCTAAAAT TCTCAAATCT AGTGTTAAAT GGACAGCCTT TGTCAAGACT 
GAAAATTCTC ATGCTGCGCA AAGTGCTCGA ATACCATCTG ATGTCAAGGT ATATAATCTT 
ACTCATCTGA ATCCATCAAC TGAGTATAAA ATTTGTATTG ATATTCCCAC CATCTATCAG 
AAAAACAGAA AAAAATGTGT AAATGTCACC ACCAAAGGTT TGCACCCTGA TCAAAAAGAG 
TATGAAAAGA ATAATACCAC AACACTTATG GCCTGTCTTG GAGGCCTTCT GGGGATTATT 
GGTGTGATAT GTCTTATCAG CTGCCTCTCT CCAGAAATGA ACTGTGATGG TGGACACAGC 
TATGTGAGGA ATTACTTACA GAAACCAACC TTTGCATTAG GTGAGCTTTA TCCTCCTCTG 
ATAAATCTCT GGGAAGCAGG AAAAGAAAAA AGTACATCAC TGAAAGTAAA AGCAACTGTT 
ATAGGTTTAC CAACAAATAT GTCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LRRN3 ( NM_001099658.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001093128.1 Homo sapiens leucine rich repeat neuronal 3 (LRRN3), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu02442
Clone ID Related Accession (Same CDS sequence)	NM_001099658.1 , NM_018334.5 , NM_001099660.1 , NM_018334.4 , NM_001099658.2
Accession Version	NM_001099658.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2127bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-03
Organism	Homo sapiens(human)
Product	leucine-rich repeat neuronal protein 3 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA494543.1, AY358280.1, BC035133.2 and AL442092.1. On Nov 24, 2018 this sequence version replaced NM_001099658.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.103722.1, SRR1803613.155770.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000308478.10/ ENSP00000312001.5 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAAGGACA TGCCACTCCG AATTCATGTG CTACTTGGCC TAGCTATCAC TACACTAGTA 
CAAGCTGTAG ATAAAAAAGT GGATTGTCCA CGGTTATGTA CGTGTGAAAT CAGGCCTTGG 
TTTACACCCA GATCCATTTA TATGGAAGCA TCTACAGTGG ATTGTAATGA TTTAGGTCTT 
TTAACTTTCC CAGCCAGATT GCCAGCTAAC ACACAGATTC TTCTCCTACA GACTAACAAT 
ATTGCAAAAA TTGAATACTC CACAGACTTT CCAGTAAACC TTACTGGCCT GGATTTATCT 
CAAAACAATT TATCTTCAGT CACCAATATT AATGTAAAAA AGATGCCTCA GCTCCTTTCT 
GTGTACCTAG AGGAAAACAA ACTTACTGAA CTGCCTGAAA AATGTCTGTC CGAACTGAGC 
AACTTACAAG AACTCTATAT TAATCACAAC TTGCTTTCTA CAATTTCACC TGGAGCCTTT 
ATTGGCCTAC ATAATCTTCT TCGACTTCAT CTCAATTCAA ATAGATTGCA GATGATCAAC 
AGTAAGTGGT TTGATGCTCT TCCAAATCTA GAGATTCTGA TGATTGGGGA AAATCCAATT 
ATCAGAATCA AAGACATGAA CTTTAAGCCT CTTATCAATC TTCGCAGCCT GGTTATAGCT 
GGTATAAACC TCACAGAAAT ACCAGATAAC GCCTTGGTTG GACTGGAAAA CTTAGAAAGC 
ATCTCTTTTT ACGATAACAG GCTTATTAAA GTACCCCATG TTGCTCTTCA AAAAGTTGTA 
AATCTCAAAT TTTTGGATCT AAATAAAAAT CCTATTAATA GAATACGAAG GGGTGATTTT 
AGCAATATGC TACACTTAAA AGAGTTGGGG ATAAATAATA TGCCTGAGCT GATTTCCATC 
GATAGTCTTG CTGTGGATAA CCTGCCAGAT TTAAGAAAAA TAGAAGCTAC TAACAACCCT 
AGATTGTCTT ACATTCACCC CAATGCATTT TTCAGACTCC CCAAGCTGGA ATCACTCATG 
CTGAACAGCA ATGCTCTCAG TGCCCTGTAC CATGGTACCA TTGAGTCTCT GCCAAACCTC 
AAGGAAATCA GCATACACAG TAACCCCATC AGGTGTGACT GTGTCATCCG TTGGATGAAC 
ATGAACAAAA CCAACATTCG ATTCATGGAG CCAGATTCAC TGTTTTGCGT GGACCCACCT 
GAATTCCAAG GTCAGAATGT TCGGCAAGTG CATTTCAGGG ACATGATGGA AATTTGTCTC 
CCTCTTATAG CTCCTGAGAG CTTTCCTTCT AATCTAAATG TAGAAGCTGG GAGCTATGTT 
TCCTTTCACT GTAGAGCTAC TGCAGAACCA CAGCCTGAAA TCTACTGGAT AACACCTTCT 
GGTCAAAAAC TCTTGCCTAA TACCCTGACA GACAAGTTCT ATGTCCATTC TGAGGGAACA 
CTAGATATAA ATGGCGTAAC TCCCAAAGAA GGGGGTTTAT ATACTTGTAT AGCAACTAAC 
CTAGTTGGCG CTGACTTGAA GTCTGTTATG ATCAAAGTGG ATGGATCTTT TCCACAAGAT 
AACAATGGCT CTTTGAATAT TAAAATAAGA GATATTCAGG CCAATTCAGT TTTGGTGTCC 
TGGAAAGCAA GTTCTAAAAT TCTCAAATCT AGTGTTAAAT GGACAGCCTT TGTCAAGACT 
GAAAATTCTC ATGCTGCGCA AAGTGCTCGA ATACCATCTG ATGTCAAGGT ATATAATCTT 
ACTCATCTGA ATCCATCAAC TGAGTATAAA ATTTGTATTG ATATTCCCAC CATCTATCAG 
AAAAACAGAA AAAAATGTGT AAATGTCACC ACCAAAGGTT TGCACCCTGA TCAAAAAGAG 
TATGAAAAGA ATAATACCAC AACACTTATG GCCTGTCTTG GAGGCCTTCT GGGGATTATT 
GGTGTGATAT GTCTTATCAG CTGCCTCTCT CCAGAAATGA ACTGTGATGG TGGACACAGC 
TATGTGAGGA ATTACTTACA GAAACCAACC TTTGCATTAG GTGAGCTTTA TCCTCCTCTG 
ATAAATCTCT GGGAAGCAGG AAAAGAAAAA AGTACATCAC TGAAAGTAAA AGCAACTGTT 
ATAGGTTTAC CAACAAATAT GTCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001093128.1
CDS	819..2945
Translation	MKDMPLRIHVLLGLAITTLVQAVDKKVDCPRLCTCEIRPWFTPRSIYMEASTVDCNDLGLLTFPARLPANTQILLLQTNNIAKIEYSTDFPVNLTGLDLSQNNLSSVTNINVKKMPQLLSVYLEENKLTELPEKCLSELSNLQELYINHNLLSTISPGAFIGLHNLLRLHLNSNRLQMINSKWFDALPNLEILMIGENPIIRIKDMNFKPLINLRSLVIAGINLTEIPDNALVGLENLESISFYDNRLIKVPHVALQKVVNLKFLDLNKNPINRIRRGDFSNMLHLKELGINNMPELISIDSLAVDNLPDLRKIEATNNPRLSYIHPNAFFRLPKLESLMLNSNALSALYHGTIESLPNLKEISIHSNPIRCDCVIRWMNMNKTNIRFMEPDSLFCVDPPEFQGQNVRQVHFRDMMEICLPLIAPESFPSNLNVEAGSYVSFHCRATAEPQPEIYWITPSGQKLLPNTLTDKFYVHSEGTLDINGVTPKEGGLYTCIATNLVGADLKSVMIKVDGSFPQDNNGSLNIKIRDIQANSVLVSWKASSKILKSSVKWTAFVKTENSHAAQSARIPSDVKVYNLTHLNPSTEYKICIDIPTIYQKNRKKCVNVTTKGLHPDQKEYEKNNTTTLMACLGGLLGIIGVICLISCLSPEMNCDGGHSYVRNYLQKPTFALGELYPPLINLWEAGKEKSTSLKVKATVIGLPTNMS

Target ORF information:

RefSeq Version	NM_001099658.2
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich repeat neuronal 3 (LRRN3), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001099658.2

ORF Insert Sequence:

ATGAAGGACA TGCCACTCCG AATTCATGTG CTACTTGGCC TAGCTATCAC TACACTAGTA 
CAAGCTGTAG ATAAAAAAGT GGATTGTCCA CGGTTATGTA CGTGTGAAAT CAGGCCTTGG 
TTTACACCCA GATCCATTTA TATGGAAGCA TCTACAGTGG ATTGTAATGA TTTAGGTCTT 
TTAACTTTCC CAGCCAGATT GCCAGCTAAC ACACAGATTC TTCTCCTACA GACTAACAAT 
ATTGCAAAAA TTGAATACTC CACAGACTTT CCAGTAAACC TTACTGGCCT GGATTTATCT 
CAAAACAATT TATCTTCAGT CACCAATATT AATGTAAAAA AGATGCCTCA GCTCCTTTCT 
GTGTACCTAG AGGAAAACAA ACTTACTGAA CTGCCTGAAA AATGTCTGTC CGAACTGAGC 
AACTTACAAG AACTCTATAT TAATCACAAC TTGCTTTCTA CAATTTCACC TGGAGCCTTT 
ATTGGCCTAC ATAATCTTCT TCGACTTCAT CTCAATTCAA ATAGATTGCA GATGATCAAC 
AGTAAGTGGT TTGATGCTCT TCCAAATCTA GAGATTCTGA TGATTGGGGA AAATCCAATT 
ATCAGAATCA AAGACATGAA CTTTAAGCCT CTTATCAATC TTCGCAGCCT GGTTATAGCT 
GGTATAAACC TCACAGAAAT ACCAGATAAC GCCTTGGTTG GACTGGAAAA CTTAGAAAGC 
ATCTCTTTTT ACGATAACAG GCTTATTAAA GTACCCCATG TTGCTCTTCA AAAAGTTGTA 
AATCTCAAAT TTTTGGATCT AAATAAAAAT CCTATTAATA GAATACGAAG GGGTGATTTT 
AGCAATATGC TACACTTAAA AGAGTTGGGG ATAAATAATA TGCCTGAGCT GATTTCCATC 
GATAGTCTTG CTGTGGATAA CCTGCCAGAT TTAAGAAAAA TAGAAGCTAC TAACAACCCT 
AGATTGTCTT ACATTCACCC CAATGCATTT TTCAGACTCC CCAAGCTGGA ATCACTCATG 
CTGAACAGCA ATGCTCTCAG TGCCCTGTAC CATGGTACCA TTGAGTCTCT GCCAAACCTC 
AAGGAAATCA GCATACACAG TAACCCCATC AGGTGTGACT GTGTCATCCG TTGGATGAAC 
ATGAACAAAA CCAACATTCG ATTCATGGAG CCAGATTCAC TGTTTTGCGT GGACCCACCT 
GAATTCCAAG GTCAGAATGT TCGGCAAGTG CATTTCAGGG ACATGATGGA AATTTGTCTC 
CCTCTTATAG CTCCTGAGAG CTTTCCTTCT AATCTAAATG TAGAAGCTGG GAGCTATGTT 
TCCTTTCACT GTAGAGCTAC TGCAGAACCA CAGCCTGAAA TCTACTGGAT AACACCTTCT 
GGTCAAAAAC TCTTGCCTAA TACCCTGACA GACAAGTTCT ATGTCCATTC TGAGGGAACA 
CTAGATATAA ATGGCGTAAC TCCCAAAGAA GGGGGTTTAT ATACTTGTAT AGCAACTAAC 
CTAGTTGGCG CTGACTTGAA GTCTGTTATG ATCAAAGTGG ATGGATCTTT TCCACAAGAT 
AACAATGGCT CTTTGAATAT TAAAATAAGA GATATTCAGG CCAATTCAGT TTTGGTGTCC 
TGGAAAGCAA GTTCTAAAAT TCTCAAATCT AGTGTTAAAT GGACAGCCTT TGTCAAGACT 
GAAAATTCTC ATGCTGCGCA AAGTGCTCGA ATACCATCTG ATGTCAAGGT ATATAATCTT 
ACTCATCTGA ATCCATCAAC TGAGTATAAA ATTTGTATTG ATATTCCCAC CATCTATCAG 
AAAAACAGAA AAAAATGTGT AAATGTCACC ACCAAAGGTT TGCACCCTGA TCAAAAAGAG 
TATGAAAAGA ATAATACCAC AACACTTATG GCCTGTCTTG GAGGCCTTCT GGGGATTATT 
GGTGTGATAT GTCTTATCAG CTGCCTCTCT CCAGAAATGA ACTGTGATGG TGGACACAGC 
TATGTGAGGA ATTACTTACA GAAACCAACC TTTGCATTAG GTGAGCTTTA TCCTCCTCTG 
ATAAATCTCT GGGAAGCAGG AAAAGAAAAA AGTACATCAC TGAAAGTAAA AGCAACTGTT 
ATAGGTTTAC CAACAAATAT GTCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Intracellular fragment of NLRR3 (NLRR3-ICD) stimulates ATRA-dependent neuroblastoma differentiation.
Biochemical and biophysical research communications453(1)86-93(2014 Oct)
Akter J,Takatori A,Islam MS,Nakazawa A,Ozaki T,Nagase H,Nakagawara A

Expression of NLRR3 orphan receptor gene is negatively regulated by MYCN and Miz-1, and its downregulation is associated with unfavorable outcome in neuroblastoma.
Clinical cancer research : an official journal of the American Association for Cancer Research17(21)6681-92(2011 Nov)
Akter J,Takatori A,Hossain MS,Ozaki T,Nakazawa A,Ohira M,Suenaga Y,Nakagawara A

Polymorphisms in leucine-rich repeat genes are associated with autism spectrum disorder susceptibility in populations of European ancestry.
Molecular autism1(1)7(2010 Mar)
Sousa I,Clark TG,Holt R,Pagnamenta AT,Mulder EJ,Minderaa RB,Bailey AJ,Battaglia A,Klauck SM,Poustka F,Monaco AP,

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.
Genome research13(10)2265-70(2003 Oct)
Clark HF,Gurney AL,Abaya E,Baker K,Baldwin D,Brush J,Chen J,Chow B,Chui C,Crowley C,Currell B,Deuel B,Dowd P,Eaton D,Foster J,Grimaldi C,Gu Q,Hass PE,Heldens S,Huang A,Kim HS,Klimowski L,Jin Y,Johnson S,Lee J,Lewis L,Liao D,Mark M,Robbie E,Sanchez C,Schoenfeld J,Seshagiri S,Simmons L,Singh J,Smith V,Stinson J,Vagts A,Vandlen R,Watanabe C,Wieand D,Woods K,Xie MH,Yansura D,Yi S,Yu G,Yuan J,Zhang M,Zhang Z,Goddard A,Wood WI,Godowski P,Gray A

Rat neuronal leucine-rich repeat protein-3: cloning and regulation of the gene expression.
Biochemical and biophysical research communications287(1)257-63(2001 Sep)
Fukamachi K,Matsuoka Y,Kitanaka C,Kuchino Y,Tsuda H

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LRRN3 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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