GNL3L cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	GNL3L
Entrez Gene ID	54552
Full Name	G protein nucleolar 3 like
Synonyms	GNL3B
General protein information	Preferred Names G protein nucleolar 3 like Names guanine nucleotide-binding protein-like 3-like protein G protein nucleolar 3B guanine nucleotide binding protein-like 3 (nucleolar)-like novel GTPase
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: X Map Location: Xp11.22
Summary	The protein encoded by this gene appears to be a nucleolar GTPase that is essential for ribosomal pre-rRNA processing and cell proliferation. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, May 2010].
Disorder MIM:	300873

mRNA and Protein(s)

mRNA	Protein	Name
NM_001184819.2	NP_001171748.1	guanine nucleotide-binding protein-like 3-like protein
NM_001184819.1	NP_001171748.1	guanine nucleotide-binding protein-like 3-like protein
XM_011530799.1	XP_011529101.1	guanine nucleotide-binding protein-like 3-like protein isoform X1
NM_019067.6	NP_061940.1	guanine nucleotide-binding protein-like 3-like protein
NM_019067.5	NP_061940.1	guanine nucleotide-binding protein-like 3-like protein

Pathways from BioSystems

Homologies

Homo sapiens (human)	GNL3L	NP_061940.1
Canis lupus familiaris (dog)	GNL3L	XP_005641448.1
Rattus norvegicus (Norway rat)	Gnl3l	NP_001075427.1
	GNL3L	XP_001090251.1
Mus musculus (house mouse)	Gnl3l	NP_932778.1
Pan troglodytes (chimpanzee)	GNL3L	XP_003954054.1
Bos taurus (cattle)	GNL3L	NP_001029479.1

Gene Ontology
Bibliography

Related articles in PubMed

Leucine Zipper Down-regulated in Cancer-1 (LDOC1) interacts with Guanine nucleotide binding protein-like 3-like (GNL3L) to modulate Nuclear Factor-kappa B (NF-?B) signaling during cell proliferation.
Thoompumkal IJ, Rehna K, Anbarasu K, Mahalingam S
Cell cycle (Georgetown, Tex.)15(23)3251-3267(2016 Dec)

GNL3L Is a Nucleo-Cytoplasmic Shuttling Protein: Role in Cell Cycle Regulation.
Thoompumkal IJ, Subba Rao MR, Kumaraswamy A, Krishnan R, Mahalingam S
PloS one10(8)e0135845(2015)

Nucleostemin and GNL3L exercise distinct functions in genome protection and ribosome synthesis, respectively.
Lin T, Meng L, Lin TC, Wu LJ, Pederson T, Tsai RY
Journal of cell science127(Pt 10)2302-12(2014 May)

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J, Hentze MW
Cell149(6)1393-406(2012 Jun)

Continual expression throughout the cell cycle and downregulation upon adipogenic differentiation makes nucleostemin a vital human MSC proliferation marker.
Oktar PA, Yildirim S, Balci D, Can A
Stem cell reviews7(2)413-24(2011 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

GNL3L-LDOC1 interplay regulates cell proliferation through the modulation of NF-kappaB pathway during tumorigenesis.
Title: Leucine Zipper Down-regulated in Cancer-1 (LDOC1) interacts with Guanine nucleotide binding protein-like 3-like (GNL3L) to modulate Nuclear Factor-kappa B (NF-?B) signaling during cell proliferation.

the present study provides evidence that GNL3L is exported from the nucleus in CRM1 dependent manner and the nuclear localization of GNL3L is important to promote 'S' phase progression during cell proliferation.
Title: GNL3L Is a Nucleo-Cytoplasmic Shuttling Protein: Role in Cell Cycle Regulation.

GNL3L depletion impairs ribosome production without inducing appreciable DNA damage. During evolution, GNL3L retained the role of the ancestral gene in ribosome biosynthesis, whereas the paralogous nucleostemin acquired a novel genome-protective function.
Title: Nucleostemin and GNL3L exercise distinct functions in genome protection and ribosome synthesis, respectively.

differences in the relative nucleostemin protein and mRNA levels may reflect the degree of proliferation of mesnchymal stem cells and can be used to characterize in vitro expansion capabilities
Title: Continual expression throughout the cell cycle and downregulation upon adipogenic differentiation makes nucleostemin a vital human MSC proliferation marker.

GNL3L bound MDM2 in vivo, stabilizing MDM2 and preventing its ubiquitylation. GNL3L depletion upregulated specific p53 targets (Bax, 14-3-3sigma and p21).
Title: GNL3L depletion destabilizes MDM2 and induces p53-dependent G2/M arrest.

The following GNL3L gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GNL3L cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu10339	NM_019067.6 Latest version!	Homo sapiens G protein nucleolar 3 like (GNL3L), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu10339	NM_001184819.2 Latest version!	Homo sapiens G protein nucleolar 3 like (GNL3L), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu10339	XM_011530799.1 Latest version!	Homo sapiens guanine nucleotide binding protein-like 3 (nucleolar)-like (GNL3L), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
View Old Accession Versions >>
OHu10339	NM_001184819.1	Homo sapiens G protein nucleolar 3 like (GNL3L), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu10339	NM_019067.5	Homo sapiens G protein nucleolar 3 like (GNL3L), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

GNL3L ( NM_001184819.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001171748.1 Homo sapiens G protein nucleolar 3 like (GNL3L), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu10339
Clone ID Related Accession (Same CDS sequence)	NM_001184819.2 , NM_001184819.1 , XM_011530799.1 , NM_019067.6 , NM_019067.5
Accession Version	NM_001184819.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1749bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Homo sapiens(human)
Product	guanine nucleotide-binding protein-like 3-like protein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK001475.1, BC003603.1, BQ674906.1 and AL391139.19. On Nov 23, 2018 this sequence version replaced NM_001184819.1. Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.153172.1, SRR1163657.539830.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000360845.3/ ENSP00000354091.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGATGAAAC TTAGACACAA AAATAAAAAG CCAGGTGAAG GTTCCAAGGG CCACAAGAAG 
ATAAGTTGGC CCTACCCTCA GCCTGCAAAG CAAAATGGGA AGAAAGCAAC CTCCAAAGTG 
CCCTCTGCAC CTCATTTTGT TCACCCCAAT GATCATGCCA ATCGAGAGGC TGAATTAAAG 
AAGAAGTGGG TTGAGGAGAT GAGGGAGAAG CAGCAAGCCG CCCGGGAGCA AGAAAGACAA 
AAACGCAGGA CCATTGAGAG CTACTGTCAG GATGTCCTAA GACGCCAGGA GGAGTTTGAG 
CATAAGGAGG AAGTTTTGCA GGAATTAAAT ATGTTTCCTC AGCTGGATGA CGAGGCCACG 
AGGAAGGCTT ATTACAAGGA GTTCCGTAAG GTGGTGGAAT ACTCTGATGT GATTCTGGAA 
GTCCTGGATG CCAGAGACCC ATTAGGCTGC CGCTGCTTCC AAATGGAGGA GGCTGTCCTG 
CGAGCACAAG GCAACAAGAA GCTGGTCCTG GTCTTGAACA AGATTGACCT GGTCCCCAAG 
GAGGTTGTGG AGAAATGGCT GGATTACCTT CGGAATGAGT TGCCAACCGT GGCTTTCAAG 
GCCAGTACCC AGCATCAGGT CAAAAACCTG AATCGTTGCA GTGTGCCAGT AGATCAGGCC 
TCTGAGTCAC TGCTGAAAAG CAAAGCCTGC TTTGGAGCTG AAAACCTCAT GAGGGTTCTG 
GGGAACTATT GCCGCCTTGG TGAAGTGCGC ACCCACATTC GTGTGGGTGT TGTGGGTCTT 
CCCAATGTTG GGAAGAGCAG CCTGATCAAT AGCCTGAAGC GCAGCCGCGC ATGCAGCGTG 
GGAGCTGTTC CTGGAATTAC CAAATTCATG CAGGAGGTCT ACCTGGACAA GTTCATCCGG 
CTCTTGGATG CTCCAGGCAT TGTCCCAGGG CCCAACTCAG AGGTGGGCAC CATCCTGCGT 
AACTGCGTCC ACGTGCAGAA GCTGGCAGAC CCTGTGACCC CAGTGGAGAC CATCCTGCAG 
CGCTGCAACC TGGAGGAGAT TTCCAACTAT TATGGCGTCT CTGGGTTCCA GACCACTGAG 
CACTTTCTGA CGGCAGTGGC CCACCGTTTG GGGAAGAAGA AGAAGGGAGG CTTATATAGT 
CAGGAACAGG CGGCCAAAGC TGTCCTAGCT GACTGGGTGA GCGGGAAGAT CAGCTTCTAT 
ATACCACCAC CAGCCACTCA CACTCTGCCC ACCCATCTCA GTGCTGAGAT CGTTAAGGAA 
ATGACCGAGG TCTTTGACAT CGAGGATACT GAGCAGGCCA ATGAAGACAC CATGGAATGC 
TTGGCCACCG GAGAATCTGA TGAGCTGTTG GGTGACACGG ACCCACTTGA AATGGAGATC 
AAGTTGCTCC ATTCTCCGAT GACGAAAATA GCAGATGCCA TTGAAAATAA AACCACCGTG 
TATAAGATTG GAGATCTCAC TGGGTATTGC ACCAATCCGA ACCGTCATCA GATGGGGTGG 
GCTAAACGCA ATGTGGACCA CCGCCCTAAG AGCAACAGTA TGGTGGATGT CTGCTCAGTG 
GACCGCCGCT CAGTGCTGCA GAGGATCATG GAGACGGACC CCCTGCAACA GGGCCAGGCT 
CTGGCATCTG CCCTGAAAAA TAAGAAGAAG ATGCAGAAAC GTGCAGATAA AATCGCCAGC 
AAGCTGTCTG ATTCCATGAT GTCTGCTCTC GACCTCTCTG GCAATGCTGA TGATGGTGTT 
GGTGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001171748.1
CDS	249..1997
Translation	MMKLRHKNKKPGEGSKGHKKISWPYPQPAKQNGKKATSKVPSAPHFVHPNDHANREAELKKKWVEEMREKQQAAREQERQKRRTIESYCQDVLRRQEEFEHKEEVLQELNMFPQLDDEATRKAYYKEFRKVVEYSDVILEVLDARDPLGCRCFQMEEAVLRAQGNKKLVLVLNKIDLVPKEVVEKWLDYLRNELPTVAFKASTQHQVKNLNRCSVPVDQASESLLKSKACFGAENLMRVLGNYCRLGEVRTHIRVGVVGLPNVGKSSLINSLKRSRACSVGAVPGITKFMQEVYLDKFIRLLDAPGIVPGPNSEVGTILRNCVHVQKLADPVTPVETILQRCNLEEISNYYGVSGFQTTEHFLTAVAHRLGKKKKGGLYSQEQAAKAVLADWVSGKISFYIPPPATHTLPTHLSAEIVKEMTEVFDIEDTEQANEDTMECLATGESDELLGDTDPLEMEIKLLHSPMTKIADAIENKTTVYKIGDLTGYCTNPNRHQMGWAKRNVDHRPKSNSMVDVCSVDRRSVLQRIMETDPLQQGQALASALKNKKKMQKRADKIASKLSDSMMSALDLSGNADDGVGD

Target ORF information:

RefSeq Version	NM_001184819.2
Organism	Homo sapiens(human)
Definition	Homo sapiens G protein nucleolar 3 like (GNL3L), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001184819.2

ORF Insert Sequence:

ATGATGAAAC TTAGACACAA AAATAAAAAG CCAGGTGAAG GTTCCAAGGG CCACAAGAAG 
ATAAGTTGGC CCTACCCTCA GCCTGCAAAG CAAAATGGGA AGAAAGCAAC CTCCAAAGTG 
CCCTCTGCAC CTCATTTTGT TCACCCCAAT GATCATGCCA ATCGAGAGGC TGAATTAAAG 
AAGAAGTGGG TTGAGGAGAT GAGGGAGAAG CAGCAAGCCG CCCGGGAGCA AGAAAGACAA 
AAACGCAGGA CCATTGAGAG CTACTGTCAG GATGTCCTAA GACGCCAGGA GGAGTTTGAG 
CATAAGGAGG AAGTTTTGCA GGAATTAAAT ATGTTTCCTC AGCTGGATGA CGAGGCCACG 
AGGAAGGCTT ATTACAAGGA GTTCCGTAAG GTGGTGGAAT ACTCTGATGT GATTCTGGAA 
GTCCTGGATG CCAGAGACCC ATTAGGCTGC CGCTGCTTCC AAATGGAGGA GGCTGTCCTG 
CGAGCACAAG GCAACAAGAA GCTGGTCCTG GTCTTGAACA AGATTGACCT GGTCCCCAAG 
GAGGTTGTGG AGAAATGGCT GGATTACCTT CGGAATGAGT TGCCAACCGT GGCTTTCAAG 
GCCAGTACCC AGCATCAGGT CAAAAACCTG AATCGTTGCA GTGTGCCAGT AGATCAGGCC 
TCTGAGTCAC TGCTGAAAAG CAAAGCCTGC TTTGGAGCTG AAAACCTCAT GAGGGTTCTG 
GGGAACTATT GCCGCCTTGG TGAAGTGCGC ACCCACATTC GTGTGGGTGT TGTGGGTCTT 
CCCAATGTTG GGAAGAGCAG CCTGATCAAT AGCCTGAAGC GCAGCCGCGC ATGCAGCGTG 
GGAGCTGTTC CTGGAATTAC CAAATTCATG CAGGAGGTCT ACCTGGACAA GTTCATCCGG 
CTCTTGGATG CTCCAGGCAT TGTCCCAGGG CCCAACTCAG AGGTGGGCAC CATCCTGCGT 
AACTGCGTCC ACGTGCAGAA GCTGGCAGAC CCTGTGACCC CAGTGGAGAC CATCCTGCAG 
CGCTGCAACC TGGAGGAGAT TTCCAACTAT TATGGCGTCT CTGGGTTCCA GACCACTGAG 
CACTTTCTGA CGGCAGTGGC CCACCGTTTG GGGAAGAAGA AGAAGGGAGG CTTATATAGT 
CAGGAACAGG CGGCCAAAGC TGTCCTAGCT GACTGGGTGA GCGGGAAGAT CAGCTTCTAT 
ATACCACCAC CAGCCACTCA CACTCTGCCC ACCCATCTCA GTGCTGAGAT CGTTAAGGAA 
ATGACCGAGG TCTTTGACAT CGAGGATACT GAGCAGGCCA ATGAAGACAC CATGGAATGC 
TTGGCCACCG GAGAATCTGA TGAGCTGTTG GGTGACACGG ACCCACTTGA AATGGAGATC 
AAGTTGCTCC ATTCTCCGAT GACGAAAATA GCAGATGCCA TTGAAAATAA AACCACCGTG 
TATAAGATTG GAGATCTCAC TGGGTATTGC ACCAATCCGA ACCGTCATCA GATGGGGTGG 
GCTAAACGCA ATGTGGACCA CCGCCCTAAG AGCAACAGTA TGGTGGATGT CTGCTCAGTG 
GACCGCCGCT CAGTGCTGCA GAGGATCATG GAGACGGACC CCCTGCAACA GGGCCAGGCT 
CTGGCATCTG CCCTGAAAAA TAAGAAGAAG ATGCAGAAAC GTGCAGATAA AATCGCCAGC 
AAGCTGTCTG ATTCCATGAT GTCTGCTCTC GACCTCTCTG GCAATGCTGA TGATGGTGTT 
GGTGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GNL3L ( NM_001184819.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001171748.1 Homo sapiens G protein nucleolar 3 like (GNL3L), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu10339
Clone ID Related Accession (Same CDS sequence)	NM_001184819.2 , NM_001184819.1 , XM_011530799.1 , NM_019067.6 , NM_019067.5
Accession Version	NM_001184819.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1749bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-11-01
Organism	Homo sapiens(human)
Product	guanine nucleotide-binding protein-like 3-like protein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK001475.1, BC003603.1, BQ674906.1 and AL391139.19. Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.153172.1, SRR1163657.539830.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGATGAAAC TTAGACACAA AAATAAAAAG CCAGGTGAAG GTTCCAAGGG CCACAAGAAG 
ATAAGTTGGC CCTACCCTCA GCCTGCAAAG CAAAATGGGA AGAAAGCAAC CTCCAAAGTG 
CCCTCTGCAC CTCATTTTGT TCACCCCAAT GATCATGCCA ATCGAGAGGC TGAATTAAAG 
AAGAAGTGGG TTGAGGAGAT GAGGGAGAAG CAGCAAGCCG CCCGGGAGCA AGAAAGACAA 
AAACGCAGGA CCATTGAGAG CTACTGTCAG GATGTCCTAA GACGCCAGGA GGAGTTTGAG 
CATAAGGAGG AAGTTTTGCA GGAATTAAAT ATGTTTCCTC AGCTGGATGA CGAGGCCACG 
AGGAAGGCTT ATTACAAGGA GTTCCGTAAG GTGGTGGAAT ACTCTGATGT GATTCTGGAA 
GTCCTGGATG CCAGAGACCC ATTAGGCTGC CGCTGCTTCC AAATGGAGGA GGCTGTCCTG 
CGAGCACAAG GCAACAAGAA GCTGGTCCTG GTCTTGAACA AGATTGACCT GGTCCCCAAG 
GAGGTTGTGG AGAAATGGCT GGATTACCTT CGGAATGAGT TGCCAACCGT GGCTTTCAAG 
GCCAGTACCC AGCATCAGGT CAAAAACCTG AATCGTTGCA GTGTGCCAGT AGATCAGGCC 
TCTGAGTCAC TGCTGAAAAG CAAAGCCTGC TTTGGAGCTG AAAACCTCAT GAGGGTTCTG 
GGGAACTATT GCCGCCTTGG TGAAGTGCGC ACCCACATTC GTGTGGGTGT TGTGGGTCTT 
CCCAATGTTG GGAAGAGCAG CCTGATCAAT AGCCTGAAGC GCAGCCGCGC ATGCAGCGTG 
GGAGCTGTTC CTGGAATTAC CAAATTCATG CAGGAGGTCT ACCTGGACAA GTTCATCCGG 
CTCTTGGATG CTCCAGGCAT TGTCCCAGGG CCCAACTCAG AGGTGGGCAC CATCCTGCGT 
AACTGCGTCC ACGTGCAGAA GCTGGCAGAC CCTGTGACCC CAGTGGAGAC CATCCTGCAG 
CGCTGCAACC TGGAGGAGAT TTCCAACTAT TATGGCGTCT CTGGGTTCCA GACCACTGAG 
CACTTTCTGA CGGCAGTGGC CCACCGTTTG GGGAAGAAGA AGAAGGGAGG CTTATATAGT 
CAGGAACAGG CGGCCAAAGC TGTCCTAGCT GACTGGGTGA GCGGGAAGAT CAGCTTCTAT 
ATACCACCAC CAGCCACTCA CACTCTGCCC ACCCATCTCA GTGCTGAGAT CGTTAAGGAA 
ATGACCGAGG TCTTTGACAT CGAGGATACT GAGCAGGCCA ATGAAGACAC CATGGAATGC 
TTGGCCACCG GAGAATCTGA TGAGCTGTTG GGTGACACGG ACCCACTTGA AATGGAGATC 
AAGTTGCTCC ATTCTCCGAT GACGAAAATA GCAGATGCCA TTGAAAATAA AACCACCGTG 
TATAAGATTG GAGATCTCAC TGGGTATTGC ACCAATCCGA ACCGTCATCA GATGGGGTGG 
GCTAAACGCA ATGTGGACCA CCGCCCTAAG AGCAACAGTA TGGTGGATGT CTGCTCAGTG 
GACCGCCGCT CAGTGCTGCA GAGGATCATG GAGACGGACC CCCTGCAACA GGGCCAGGCT 
CTGGCATCTG CCCTGAAAAA TAAGAAGAAG ATGCAGAAAC GTGCAGATAA AATCGCCAGC 
AAGCTGTCTG ATTCCATGAT GTCTGCTCTC GACCTCTCTG GCAATGCTGA TGATGGTGTT 
GGTGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001171748.1
CDS	257..2005
Translation	MMKLRHKNKKPGEGSKGHKKISWPYPQPAKQNGKKATSKVPSAPHFVHPNDHANREAELKKKWVEEMREKQQAAREQERQKRRTIESYCQDVLRRQEEFEHKEEVLQELNMFPQLDDEATRKAYYKEFRKVVEYSDVILEVLDARDPLGCRCFQMEEAVLRAQGNKKLVLVLNKIDLVPKEVVEKWLDYLRNELPTVAFKASTQHQVKNLNRCSVPVDQASESLLKSKACFGAENLMRVLGNYCRLGEVRTHIRVGVVGLPNVGKSSLINSLKRSRACSVGAVPGITKFMQEVYLDKFIRLLDAPGIVPGPNSEVGTILRNCVHVQKLADPVTPVETILQRCNLEEISNYYGVSGFQTTEHFLTAVAHRLGKKKKGGLYSQEQAAKAVLADWVSGKISFYIPPPATHTLPTHLSAEIVKEMTEVFDIEDTEQANEDTMECLATGESDELLGDTDPLEMEIKLLHSPMTKIADAIENKTTVYKIGDLTGYCTNPNRHQMGWAKRNVDHRPKSNSMVDVCSVDRRSVLQRIMETDPLQQGQALASALKNKKKMQKRADKIASKLSDSMMSALDLSGNADDGVGD

Target ORF information:

RefSeq Version	NM_001184819.1
Organism	Homo sapiens(human)
Definition	Homo sapiens G protein nucleolar 3 like (GNL3L), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001184819.1

ORF Insert Sequence:

ATGATGAAAC TTAGACACAA AAATAAAAAG CCAGGTGAAG GTTCCAAGGG CCACAAGAAG 
ATAAGTTGGC CCTACCCTCA GCCTGCAAAG CAAAATGGGA AGAAAGCAAC CTCCAAAGTG 
CCCTCTGCAC CTCATTTTGT TCACCCCAAT GATCATGCCA ATCGAGAGGC TGAATTAAAG 
AAGAAGTGGG TTGAGGAGAT GAGGGAGAAG CAGCAAGCCG CCCGGGAGCA AGAAAGACAA 
AAACGCAGGA CCATTGAGAG CTACTGTCAG GATGTCCTAA GACGCCAGGA GGAGTTTGAG 
CATAAGGAGG AAGTTTTGCA GGAATTAAAT ATGTTTCCTC AGCTGGATGA CGAGGCCACG 
AGGAAGGCTT ATTACAAGGA GTTCCGTAAG GTGGTGGAAT ACTCTGATGT GATTCTGGAA 
GTCCTGGATG CCAGAGACCC ATTAGGCTGC CGCTGCTTCC AAATGGAGGA GGCTGTCCTG 
CGAGCACAAG GCAACAAGAA GCTGGTCCTG GTCTTGAACA AGATTGACCT GGTCCCCAAG 
GAGGTTGTGG AGAAATGGCT GGATTACCTT CGGAATGAGT TGCCAACCGT GGCTTTCAAG 
GCCAGTACCC AGCATCAGGT CAAAAACCTG AATCGTTGCA GTGTGCCAGT AGATCAGGCC 
TCTGAGTCAC TGCTGAAAAG CAAAGCCTGC TTTGGAGCTG AAAACCTCAT GAGGGTTCTG 
GGGAACTATT GCCGCCTTGG TGAAGTGCGC ACCCACATTC GTGTGGGTGT TGTGGGTCTT 
CCCAATGTTG GGAAGAGCAG CCTGATCAAT AGCCTGAAGC GCAGCCGCGC ATGCAGCGTG 
GGAGCTGTTC CTGGAATTAC CAAATTCATG CAGGAGGTCT ACCTGGACAA GTTCATCCGG 
CTCTTGGATG CTCCAGGCAT TGTCCCAGGG CCCAACTCAG AGGTGGGCAC CATCCTGCGT 
AACTGCGTCC ACGTGCAGAA GCTGGCAGAC CCTGTGACCC CAGTGGAGAC CATCCTGCAG 
CGCTGCAACC TGGAGGAGAT TTCCAACTAT TATGGCGTCT CTGGGTTCCA GACCACTGAG 
CACTTTCTGA CGGCAGTGGC CCACCGTTTG GGGAAGAAGA AGAAGGGAGG CTTATATAGT 
CAGGAACAGG CGGCCAAAGC TGTCCTAGCT GACTGGGTGA GCGGGAAGAT CAGCTTCTAT 
ATACCACCAC CAGCCACTCA CACTCTGCCC ACCCATCTCA GTGCTGAGAT CGTTAAGGAA 
ATGACCGAGG TCTTTGACAT CGAGGATACT GAGCAGGCCA ATGAAGACAC CATGGAATGC 
TTGGCCACCG GAGAATCTGA TGAGCTGTTG GGTGACACGG ACCCACTTGA AATGGAGATC 
AAGTTGCTCC ATTCTCCGAT GACGAAAATA GCAGATGCCA TTGAAAATAA AACCACCGTG 
TATAAGATTG GAGATCTCAC TGGGTATTGC ACCAATCCGA ACCGTCATCA GATGGGGTGG 
GCTAAACGCA ATGTGGACCA CCGCCCTAAG AGCAACAGTA TGGTGGATGT CTGCTCAGTG 
GACCGCCGCT CAGTGCTGCA GAGGATCATG GAGACGGACC CCCTGCAACA GGGCCAGGCT 
CTGGCATCTG CCCTGAAAAA TAAGAAGAAG ATGCAGAAAC GTGCAGATAA AATCGCCAGC 
AAGCTGTCTG ATTCCATGAT GTCTGCTCTC GACCTCTCTG GCAATGCTGA TGATGGTGTT 
GGTGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GNL3L ( NM_019067.6 ) cDNA ORF clone, Homo sapiens(human) -> NP_061940.1 Homo sapiens G protein nucleolar 3 like (GNL3L), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu10339
Clone ID Related Accession (Same CDS sequence)	NM_001184819.2 , NM_001184819.1 , XM_011530799.1 , NM_019067.6 , NM_019067.5
Accession Version	NM_019067.6 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1749bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-27
Organism	Homo sapiens(human)
Product	guanine nucleotide-binding protein-like 3-like protein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK001475.1, BQ674906.1 and AL391139.19. This sequence is a reference standard in the RefSeqGene project. On May 31, 2019 this sequence version replaced NM_019067.5. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK001475.1, SRR1803616.91106.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGATGAAAC TTAGACACAA AAATAAAAAG CCAGGTGAAG GTTCCAAGGG CCACAAGAAG 
ATAAGTTGGC CCTACCCTCA GCCTGCAAAG CAAAATGGGA AGAAAGCAAC CTCCAAAGTG 
CCCTCTGCAC CTCATTTTGT TCACCCCAAT GATCATGCCA ATCGAGAGGC TGAATTAAAG 
AAGAAGTGGG TTGAGGAGAT GAGGGAGAAG CAGCAAGCCG CCCGGGAGCA AGAAAGACAA 
AAACGCAGGA CCATTGAGAG CTACTGTCAG GATGTCCTAA GACGCCAGGA GGAGTTTGAG 
CATAAGGAGG AAGTTTTGCA GGAATTAAAT ATGTTTCCTC AGCTGGATGA CGAGGCCACG 
AGGAAGGCTT ATTACAAGGA GTTCCGTAAG GTGGTGGAAT ACTCTGATGT GATTCTGGAA 
GTCCTGGATG CCAGAGACCC ATTAGGCTGC CGCTGCTTCC AAATGGAGGA GGCTGTCCTG 
CGAGCACAAG GCAACAAGAA GCTGGTCCTG GTCTTGAACA AGATTGACCT GGTCCCCAAG 
GAGGTTGTGG AGAAATGGCT GGATTACCTT CGGAATGAGT TGCCAACCGT GGCTTTCAAG 
GCCAGTACCC AGCATCAGGT CAAAAACCTG AATCGTTGCA GTGTGCCAGT AGATCAGGCC 
TCTGAGTCAC TGCTGAAAAG CAAAGCCTGC TTTGGAGCTG AAAACCTCAT GAGGGTTCTG 
GGGAACTATT GCCGCCTTGG TGAAGTGCGC ACCCACATTC GTGTGGGTGT TGTGGGTCTT 
CCCAATGTTG GGAAGAGCAG CCTGATCAAT AGCCTGAAGC GCAGCCGCGC ATGCAGCGTG 
GGAGCTGTTC CTGGAATTAC CAAATTCATG CAGGAGGTCT ACCTGGACAA GTTCATCCGG 
CTCTTGGATG CTCCAGGCAT TGTCCCAGGG CCCAACTCAG AGGTGGGCAC CATCCTGCGT 
AACTGCGTCC ACGTGCAGAA GCTGGCAGAC CCTGTGACCC CAGTGGAGAC CATCCTGCAG 
CGCTGCAACC TGGAGGAGAT TTCCAACTAT TATGGCGTCT CTGGGTTCCA GACCACTGAG 
CACTTTCTGA CGGCAGTGGC CCACCGTTTG GGGAAGAAGA AGAAGGGAGG CTTATATAGT 
CAGGAACAGG CGGCCAAAGC TGTCCTAGCT GACTGGGTGA GCGGGAAGAT CAGCTTCTAT 
ATACCACCAC CAGCCACTCA CACTCTGCCC ACCCATCTCA GTGCTGAGAT CGTTAAGGAA 
ATGACCGAGG TCTTTGACAT CGAGGATACT GAGCAGGCCA ATGAAGACAC CATGGAATGC 
TTGGCCACCG GAGAATCTGA TGAGCTGTTG GGTGACACGG ACCCACTTGA AATGGAGATC 
AAGTTGCTCC ATTCTCCGAT GACGAAAATA GCAGATGCCA TTGAAAATAA AACCACCGTG 
TATAAGATTG GAGATCTCAC TGGGTATTGC ACCAATCCGA ACCGTCATCA GATGGGGTGG 
GCTAAACGCA ATGTGGACCA CCGCCCTAAG AGCAACAGTA TGGTGGATGT CTGCTCAGTG 
GACCGCCGCT CAGTGCTGCA GAGGATCATG GAGACGGACC CCCTGCAACA GGGCCAGGCT 
CTGGCATCTG CCCTGAAAAA TAAGAAGAAG ATGCAGAAAC GTGCAGATAA AATCGCCAGC 
AAGCTGTCTG ATTCCATGAT GTCTGCTCTC GACCTCTCTG GCAATGCTGA TGATGGTGTT 
GGTGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_061940.1
CDS	132..1880
Translation	MMKLRHKNKKPGEGSKGHKKISWPYPQPAKQNGKKATSKVPSAPHFVHPNDHANREAELKKKWVEEMREKQQAAREQERQKRRTIESYCQDVLRRQEEFEHKEEVLQELNMFPQLDDEATRKAYYKEFRKVVEYSDVILEVLDARDPLGCRCFQMEEAVLRAQGNKKLVLVLNKIDLVPKEVVEKWLDYLRNELPTVAFKASTQHQVKNLNRCSVPVDQASESLLKSKACFGAENLMRVLGNYCRLGEVRTHIRVGVVGLPNVGKSSLINSLKRSRACSVGAVPGITKFMQEVYLDKFIRLLDAPGIVPGPNSEVGTILRNCVHVQKLADPVTPVETILQRCNLEEISNYYGVSGFQTTEHFLTAVAHRLGKKKKGGLYSQEQAAKAVLADWVSGKISFYIPPPATHTLPTHLSAEIVKEMTEVFDIEDTEQANEDTMECLATGESDELLGDTDPLEMEIKLLHSPMTKIADAIENKTTVYKIGDLTGYCTNPNRHQMGWAKRNVDHRPKSNSMVDVCSVDRRSVLQRIMETDPLQQGQALASALKNKKKMQKRADKIASKLSDSMMSALDLSGNADDGVGD

Target ORF information:

RefSeq Version	NM_019067.6
Organism	Homo sapiens(human)
Definition	Homo sapiens G protein nucleolar 3 like (GNL3L), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019067.6

ORF Insert Sequence:

ATGATGAAAC TTAGACACAA AAATAAAAAG CCAGGTGAAG GTTCCAAGGG CCACAAGAAG 
ATAAGTTGGC CCTACCCTCA GCCTGCAAAG CAAAATGGGA AGAAAGCAAC CTCCAAAGTG 
CCCTCTGCAC CTCATTTTGT TCACCCCAAT GATCATGCCA ATCGAGAGGC TGAATTAAAG 
AAGAAGTGGG TTGAGGAGAT GAGGGAGAAG CAGCAAGCCG CCCGGGAGCA AGAAAGACAA 
AAACGCAGGA CCATTGAGAG CTACTGTCAG GATGTCCTAA GACGCCAGGA GGAGTTTGAG 
CATAAGGAGG AAGTTTTGCA GGAATTAAAT ATGTTTCCTC AGCTGGATGA CGAGGCCACG 
AGGAAGGCTT ATTACAAGGA GTTCCGTAAG GTGGTGGAAT ACTCTGATGT GATTCTGGAA 
GTCCTGGATG CCAGAGACCC ATTAGGCTGC CGCTGCTTCC AAATGGAGGA GGCTGTCCTG 
CGAGCACAAG GCAACAAGAA GCTGGTCCTG GTCTTGAACA AGATTGACCT GGTCCCCAAG 
GAGGTTGTGG AGAAATGGCT GGATTACCTT CGGAATGAGT TGCCAACCGT GGCTTTCAAG 
GCCAGTACCC AGCATCAGGT CAAAAACCTG AATCGTTGCA GTGTGCCAGT AGATCAGGCC 
TCTGAGTCAC TGCTGAAAAG CAAAGCCTGC TTTGGAGCTG AAAACCTCAT GAGGGTTCTG 
GGGAACTATT GCCGCCTTGG TGAAGTGCGC ACCCACATTC GTGTGGGTGT TGTGGGTCTT 
CCCAATGTTG GGAAGAGCAG CCTGATCAAT AGCCTGAAGC GCAGCCGCGC ATGCAGCGTG 
GGAGCTGTTC CTGGAATTAC CAAATTCATG CAGGAGGTCT ACCTGGACAA GTTCATCCGG 
CTCTTGGATG CTCCAGGCAT TGTCCCAGGG CCCAACTCAG AGGTGGGCAC CATCCTGCGT 
AACTGCGTCC ACGTGCAGAA GCTGGCAGAC CCTGTGACCC CAGTGGAGAC CATCCTGCAG 
CGCTGCAACC TGGAGGAGAT TTCCAACTAT TATGGCGTCT CTGGGTTCCA GACCACTGAG 
CACTTTCTGA CGGCAGTGGC CCACCGTTTG GGGAAGAAGA AGAAGGGAGG CTTATATAGT 
CAGGAACAGG CGGCCAAAGC TGTCCTAGCT GACTGGGTGA GCGGGAAGAT CAGCTTCTAT 
ATACCACCAC CAGCCACTCA CACTCTGCCC ACCCATCTCA GTGCTGAGAT CGTTAAGGAA 
ATGACCGAGG TCTTTGACAT CGAGGATACT GAGCAGGCCA ATGAAGACAC CATGGAATGC 
TTGGCCACCG GAGAATCTGA TGAGCTGTTG GGTGACACGG ACCCACTTGA AATGGAGATC 
AAGTTGCTCC ATTCTCCGAT GACGAAAATA GCAGATGCCA TTGAAAATAA AACCACCGTG 
TATAAGATTG GAGATCTCAC TGGGTATTGC ACCAATCCGA ACCGTCATCA GATGGGGTGG 
GCTAAACGCA ATGTGGACCA CCGCCCTAAG AGCAACAGTA TGGTGGATGT CTGCTCAGTG 
GACCGCCGCT CAGTGCTGCA GAGGATCATG GAGACGGACC CCCTGCAACA GGGCCAGGCT 
CTGGCATCTG CCCTGAAAAA TAAGAAGAAG ATGCAGAAAC GTGCAGATAA AATCGCCAGC 
AAGCTGTCTG ATTCCATGAT GTCTGCTCTC GACCTCTCTG GCAATGCTGA TGATGGTGTT 
GGTGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GNL3L ( NM_019067.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_061940.1 Homo sapiens G protein nucleolar 3 like (GNL3L), transcript variant 2, mRNA.

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CloneID	OHu10339
Clone ID Related Accession (Same CDS sequence)	NM_001184819.2 , NM_001184819.1 , XM_011530799.1 , NM_019067.6 , NM_019067.5
Accession Version	NM_019067.5	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1749bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-23
Organism	Homo sapiens(human)
Product	guanine nucleotide-binding protein-like 3-like protein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK001475.1, BQ674906.1 and AL391139.19. This sequence is a reference standard in the RefSeqGene project. On May 20, 2010 this sequence version replaced NM_019067.4. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK001475.1, SRR1803616.91106.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGATGAAAC TTAGACACAA AAATAAAAAG CCAGGTGAAG GTTCCAAGGG CCACAAGAAG 
ATAAGTTGGC CCTACCCTCA GCCTGCAAAG CAAAATGGGA AGAAAGCAAC CTCCAAAGTG 
CCCTCTGCAC CTCATTTTGT TCACCCCAAT GATCATGCCA ATCGAGAGGC TGAATTAAAG 
AAGAAGTGGG TTGAGGAGAT GAGGGAGAAG CAGCAAGCCG CCCGGGAGCA AGAAAGACAA 
AAACGCAGGA CCATTGAGAG CTACTGTCAG GATGTCCTAA GACGCCAGGA GGAGTTTGAG 
CATAAGGAGG AAGTTTTGCA GGAATTAAAT ATGTTTCCTC AGCTGGATGA CGAGGCCACG 
AGGAAGGCTT ATTACAAGGA GTTCCGTAAG GTGGTGGAAT ACTCTGATGT GATTCTGGAA 
GTCCTGGATG CCAGAGACCC ATTAGGCTGC CGCTGCTTCC AAATGGAGGA GGCTGTCCTG 
CGAGCACAAG GCAACAAGAA GCTGGTCCTG GTCTTGAACA AGATTGACCT GGTCCCCAAG 
GAGGTTGTGG AGAAATGGCT GGATTACCTT CGGAATGAGT TGCCAACCGT GGCTTTCAAG 
GCCAGTACCC AGCATCAGGT CAAAAACCTG AATCGTTGCA GTGTGCCAGT AGATCAGGCC 
TCTGAGTCAC TGCTGAAAAG CAAAGCCTGC TTTGGAGCTG AAAACCTCAT GAGGGTTCTG 
GGGAACTATT GCCGCCTTGG TGAAGTGCGC ACCCACATTC GTGTGGGTGT TGTGGGTCTT 
CCCAATGTTG GGAAGAGCAG CCTGATCAAT AGCCTGAAGC GCAGCCGCGC ATGCAGCGTG 
GGAGCTGTTC CTGGAATTAC CAAATTCATG CAGGAGGTCT ACCTGGACAA GTTCATCCGG 
CTCTTGGATG CTCCAGGCAT TGTCCCAGGG CCCAACTCAG AGGTGGGCAC CATCCTGCGT 
AACTGCGTCC ACGTGCAGAA GCTGGCAGAC CCTGTGACCC CAGTGGAGAC CATCCTGCAG 
CGCTGCAACC TGGAGGAGAT TTCCAACTAT TATGGCGTCT CTGGGTTCCA GACCACTGAG 
CACTTTCTGA CGGCAGTGGC CCACCGTTTG GGGAAGAAGA AGAAGGGAGG CTTATATAGT 
CAGGAACAGG CGGCCAAAGC TGTCCTAGCT GACTGGGTGA GCGGGAAGAT CAGCTTCTAT 
ATACCACCAC CAGCCACTCA CACTCTGCCC ACCCATCTCA GTGCTGAGAT CGTTAAGGAA 
ATGACCGAGG TCTTTGACAT CGAGGATACT GAGCAGGCCA ATGAAGACAC CATGGAATGC 
TTGGCCACCG GAGAATCTGA TGAGCTGTTG GGTGACACGG ACCCACTTGA AATGGAGATC 
AAGTTGCTCC ATTCTCCGAT GACGAAAATA GCAGATGCCA TTGAAAATAA AACCACCGTG 
TATAAGATTG GAGATCTCAC TGGGTATTGC ACCAATCCGA ACCGTCATCA GATGGGGTGG 
GCTAAACGCA ATGTGGACCA CCGCCCTAAG AGCAACAGTA TGGTGGATGT CTGCTCAGTG 
GACCGCCGCT CAGTGCTGCA GAGGATCATG GAGACGGACC CCCTGCAACA GGGCCAGGCT 
CTGGCATCTG CCCTGAAAAA TAAGAAGAAG ATGCAGAAAC GTGCAGATAA AATCGCCAGC 
AAGCTGTCTG ATTCCATGAT GTCTGCTCTC GACCTCTCTG GCAATGCTGA TGATGGTGTT 
GGTGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_061940.1
CDS	140..1888
Translation	MMKLRHKNKKPGEGSKGHKKISWPYPQPAKQNGKKATSKVPSAPHFVHPNDHANREAELKKKWVEEMREKQQAAREQERQKRRTIESYCQDVLRRQEEFEHKEEVLQELNMFPQLDDEATRKAYYKEFRKVVEYSDVILEVLDARDPLGCRCFQMEEAVLRAQGNKKLVLVLNKIDLVPKEVVEKWLDYLRNELPTVAFKASTQHQVKNLNRCSVPVDQASESLLKSKACFGAENLMRVLGNYCRLGEVRTHIRVGVVGLPNVGKSSLINSLKRSRACSVGAVPGITKFMQEVYLDKFIRLLDAPGIVPGPNSEVGTILRNCVHVQKLADPVTPVETILQRCNLEEISNYYGVSGFQTTEHFLTAVAHRLGKKKKGGLYSQEQAAKAVLADWVSGKISFYIPPPATHTLPTHLSAEIVKEMTEVFDIEDTEQANEDTMECLATGESDELLGDTDPLEMEIKLLHSPMTKIADAIENKTTVYKIGDLTGYCTNPNRHQMGWAKRNVDHRPKSNSMVDVCSVDRRSVLQRIMETDPLQQGQALASALKNKKKMQKRADKIASKLSDSMMSALDLSGNADDGVGD

Target ORF information:

RefSeq Version	NM_019067.5
Organism	Homo sapiens(human)
Definition	Homo sapiens G protein nucleolar 3 like (GNL3L), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019067.5

ORF Insert Sequence:

ATGATGAAAC TTAGACACAA AAATAAAAAG CCAGGTGAAG GTTCCAAGGG CCACAAGAAG 
ATAAGTTGGC CCTACCCTCA GCCTGCAAAG CAAAATGGGA AGAAAGCAAC CTCCAAAGTG 
CCCTCTGCAC CTCATTTTGT TCACCCCAAT GATCATGCCA ATCGAGAGGC TGAATTAAAG 
AAGAAGTGGG TTGAGGAGAT GAGGGAGAAG CAGCAAGCCG CCCGGGAGCA AGAAAGACAA 
AAACGCAGGA CCATTGAGAG CTACTGTCAG GATGTCCTAA GACGCCAGGA GGAGTTTGAG 
CATAAGGAGG AAGTTTTGCA GGAATTAAAT ATGTTTCCTC AGCTGGATGA CGAGGCCACG 
AGGAAGGCTT ATTACAAGGA GTTCCGTAAG GTGGTGGAAT ACTCTGATGT GATTCTGGAA 
GTCCTGGATG CCAGAGACCC ATTAGGCTGC CGCTGCTTCC AAATGGAGGA GGCTGTCCTG 
CGAGCACAAG GCAACAAGAA GCTGGTCCTG GTCTTGAACA AGATTGACCT GGTCCCCAAG 
GAGGTTGTGG AGAAATGGCT GGATTACCTT CGGAATGAGT TGCCAACCGT GGCTTTCAAG 
GCCAGTACCC AGCATCAGGT CAAAAACCTG AATCGTTGCA GTGTGCCAGT AGATCAGGCC 
TCTGAGTCAC TGCTGAAAAG CAAAGCCTGC TTTGGAGCTG AAAACCTCAT GAGGGTTCTG 
GGGAACTATT GCCGCCTTGG TGAAGTGCGC ACCCACATTC GTGTGGGTGT TGTGGGTCTT 
CCCAATGTTG GGAAGAGCAG CCTGATCAAT AGCCTGAAGC GCAGCCGCGC ATGCAGCGTG 
GGAGCTGTTC CTGGAATTAC CAAATTCATG CAGGAGGTCT ACCTGGACAA GTTCATCCGG 
CTCTTGGATG CTCCAGGCAT TGTCCCAGGG CCCAACTCAG AGGTGGGCAC CATCCTGCGT 
AACTGCGTCC ACGTGCAGAA GCTGGCAGAC CCTGTGACCC CAGTGGAGAC CATCCTGCAG 
CGCTGCAACC TGGAGGAGAT TTCCAACTAT TATGGCGTCT CTGGGTTCCA GACCACTGAG 
CACTTTCTGA CGGCAGTGGC CCACCGTTTG GGGAAGAAGA AGAAGGGAGG CTTATATAGT 
CAGGAACAGG CGGCCAAAGC TGTCCTAGCT GACTGGGTGA GCGGGAAGAT CAGCTTCTAT 
ATACCACCAC CAGCCACTCA CACTCTGCCC ACCCATCTCA GTGCTGAGAT CGTTAAGGAA 
ATGACCGAGG TCTTTGACAT CGAGGATACT GAGCAGGCCA ATGAAGACAC CATGGAATGC 
TTGGCCACCG GAGAATCTGA TGAGCTGTTG GGTGACACGG ACCCACTTGA AATGGAGATC 
AAGTTGCTCC ATTCTCCGAT GACGAAAATA GCAGATGCCA TTGAAAATAA AACCACCGTG 
TATAAGATTG GAGATCTCAC TGGGTATTGC ACCAATCCGA ACCGTCATCA GATGGGGTGG 
GCTAAACGCA ATGTGGACCA CCGCCCTAAG AGCAACAGTA TGGTGGATGT CTGCTCAGTG 
GACCGCCGCT CAGTGCTGCA GAGGATCATG GAGACGGACC CCCTGCAACA GGGCCAGGCT 
CTGGCATCTG CCCTGAAAAA TAAGAAGAAG ATGCAGAAAC GTGCAGATAA AATCGCCAGC 
AAGCTGTCTG ATTCCATGAT GTCTGCTCTC GACCTCTCTG GCAATGCTGA TGATGGTGTT 
GGTGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GNL3L ( XM_011530799.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011529101.1 Homo sapiens guanine nucleotide binding protein-like 3 (nucleolar)-like (GNL3L), transcript variant X1, mRNA.

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CloneID	OHu10339
Clone ID Related Accession (Same CDS sequence)	NM_001184819.2 , NM_001184819.1 , XM_011530799.1 , NM_019067.6 , NM_019067.5
Accession Version	XM_011530799.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1749bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	guanine nucleotide-binding protein-like 3-like protein isoform X1
Comment

ATGATGAAAC TTAGACACAA AAATAAAAAG CCAGGTGAAG GTTCCAAGGG CCACAAGAAG 
ATAAGTTGGC CCTACCCTCA GCCTGCAAAG CAAAATGGGA AGAAAGCAAC CTCCAAAGTG 
CCCTCTGCAC CTCATTTTGT TCACCCCAAT GATCATGCCA ATCGAGAGGC TGAATTAAAG 
AAGAAGTGGG TTGAGGAGAT GAGGGAGAAG CAGCAAGCCG CCCGGGAGCA AGAAAGACAA 
AAACGCAGGA CCATTGAGAG CTACTGTCAG GATGTCCTAA GACGCCAGGA GGAGTTTGAG 
CATAAGGAGG AAGTTTTGCA GGAATTAAAT ATGTTTCCTC AGCTGGATGA CGAGGCCACG 
AGGAAGGCTT ATTACAAGGA GTTCCGTAAG GTGGTGGAAT ACTCTGATGT GATTCTGGAA 
GTCCTGGATG CCAGAGACCC ATTAGGCTGC CGCTGCTTCC AAATGGAGGA GGCTGTCCTG 
CGAGCACAAG GCAACAAGAA GCTGGTCCTG GTCTTGAACA AGATTGACCT GGTCCCCAAG 
GAGGTTGTGG AGAAATGGCT GGATTACCTT CGGAATGAGT TGCCAACCGT GGCTTTCAAG 
GCCAGTACCC AGCATCAGGT CAAAAACCTG AATCGTTGCA GTGTGCCAGT AGATCAGGCC 
TCTGAGTCAC TGCTGAAAAG CAAAGCCTGC TTTGGAGCTG AAAACCTCAT GAGGGTTCTG 
GGGAACTATT GCCGCCTTGG TGAAGTGCGC ACCCACATTC GTGTGGGTGT TGTGGGTCTT 
CCCAATGTTG GGAAGAGCAG CCTGATCAAT AGCCTGAAGC GCAGCCGCGC ATGCAGCGTG 
GGAGCTGTTC CTGGAATTAC CAAATTCATG CAGGAGGTCT ACCTGGACAA GTTCATCCGG 
CTCTTGGATG CTCCAGGCAT TGTCCCAGGG CCCAACTCAG AGGTGGGCAC CATCCTGCGT 
AACTGCGTCC ACGTGCAGAA GCTGGCAGAC CCTGTGACCC CAGTGGAGAC CATCCTGCAG 
CGCTGCAACC TGGAGGAGAT TTCCAACTAT TATGGCGTCT CTGGGTTCCA GACCACTGAG 
CACTTTCTGA CGGCAGTGGC CCACCGTTTG GGGAAGAAGA AGAAGGGAGG CTTATATAGT 
CAGGAACAGG CGGCCAAAGC TGTCCTAGCT GACTGGGTGA GCGGGAAGAT CAGCTTCTAT 
ATACCACCAC CAGCCACTCA CACTCTGCCC ACCCATCTCA GTGCTGAGAT CGTTAAGGAA 
ATGACCGAGG TCTTTGACAT CGAGGATACT GAGCAGGCCA ATGAAGACAC CATGGAATGC 
TTGGCCACCG GAGAATCTGA TGAGCTGTTG GGTGACACGG ACCCACTTGA AATGGAGATC 
AAGTTGCTCC ATTCTCCGAT GACGAAAATA GCAGATGCCA TTGAAAATAA AACCACCGTG 
TATAAGATTG GAGATCTCAC TGGGTATTGC ACCAATCCGA ACCGTCATCA GATGGGGTGG 
GCTAAACGCA ATGTGGACCA CCGCCCTAAG AGCAACAGTA TGGTGGATGT CTGCTCAGTG 
GACCGCCGCT CAGTGCTGCA GAGGATCATG GAGACGGACC CCCTGCAACA GGGCCAGGCT 
CTGGCATCTG CCCTGAAAAA TAAGAAGAAG ATGCAGAAAC GTGCAGATAA AATCGCCAGC 
AAGCTGTCTG ATTCCATGAT GTCTGCTCTC GACCTCTCTG GCAATGCTGA TGATGGTGTT 
GGTGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

XP_011529101.1

Translation

MMKLRHKNKKPGEGSKGHKKISWPYPQPAKQNGKKATSKVPSAPHFVHPNDHANREAELKKKWVEEMREKQQAAREQERQKRRTIESYCQDVLRRQEEFEHKEEVLQELNMFPQLDDEATRKAYYKEFRKVVEYSDVILEVLDARDPLGCRCFQMEEAVLRAQGNKKLVLVLNKIDLVPKEVVEKWLDYLRNELPTVAFKASTQHQVKNLNRCSVPVDQASESLLKSKACFGAENLMRVLGNYCRLGEVRTHIRVGVVGLPNVGKSSLINSLKRSRACSVGAVPGITKFMQEVYLDKFIRLLDAPGIVPGPNSEVGTILRNCVHVQKLADPVTPVETILQRCNLEEISNYYGVSGFQTTEHFLTAVAHRLGKKKKGGLYSQEQAAKAVLADWVSGKISFYIPPPATHTLPTHLSAEIVKEMTEVFDIEDTEQANEDTMECLATGESDELLGDTDPLEMEIKLLHSPMTKIADAIENKTTVYKIGDLTGYCTNPNRHQMGWAKRNVDHRPKSNSMVDVCSVDRRSVLQRIMETDPLQQGQALASALKNKKKMQKRADKIASKLSDSMMSALDLSGNADDGVGD

Target ORF information:

RefSeq Version	XM_011530799.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens guanine nucleotide binding protein-like 3 (nucleolar)-like (GNL3L), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011530799.1

ORF Insert Sequence:

ATGATGAAAC TTAGACACAA AAATAAAAAG CCAGGTGAAG GTTCCAAGGG CCACAAGAAG 
ATAAGTTGGC CCTACCCTCA GCCTGCAAAG CAAAATGGGA AGAAAGCAAC CTCCAAAGTG 
CCCTCTGCAC CTCATTTTGT TCACCCCAAT GATCATGCCA ATCGAGAGGC TGAATTAAAG 
AAGAAGTGGG TTGAGGAGAT GAGGGAGAAG CAGCAAGCCG CCCGGGAGCA AGAAAGACAA 
AAACGCAGGA CCATTGAGAG CTACTGTCAG GATGTCCTAA GACGCCAGGA GGAGTTTGAG 
CATAAGGAGG AAGTTTTGCA GGAATTAAAT ATGTTTCCTC AGCTGGATGA CGAGGCCACG 
AGGAAGGCTT ATTACAAGGA GTTCCGTAAG GTGGTGGAAT ACTCTGATGT GATTCTGGAA 
GTCCTGGATG CCAGAGACCC ATTAGGCTGC CGCTGCTTCC AAATGGAGGA GGCTGTCCTG 
CGAGCACAAG GCAACAAGAA GCTGGTCCTG GTCTTGAACA AGATTGACCT GGTCCCCAAG 
GAGGTTGTGG AGAAATGGCT GGATTACCTT CGGAATGAGT TGCCAACCGT GGCTTTCAAG 
GCCAGTACCC AGCATCAGGT CAAAAACCTG AATCGTTGCA GTGTGCCAGT AGATCAGGCC 
TCTGAGTCAC TGCTGAAAAG CAAAGCCTGC TTTGGAGCTG AAAACCTCAT GAGGGTTCTG 
GGGAACTATT GCCGCCTTGG TGAAGTGCGC ACCCACATTC GTGTGGGTGT TGTGGGTCTT 
CCCAATGTTG GGAAGAGCAG CCTGATCAAT AGCCTGAAGC GCAGCCGCGC ATGCAGCGTG 
GGAGCTGTTC CTGGAATTAC CAAATTCATG CAGGAGGTCT ACCTGGACAA GTTCATCCGG 
CTCTTGGATG CTCCAGGCAT TGTCCCAGGG CCCAACTCAG AGGTGGGCAC CATCCTGCGT 
AACTGCGTCC ACGTGCAGAA GCTGGCAGAC CCTGTGACCC CAGTGGAGAC CATCCTGCAG 
CGCTGCAACC TGGAGGAGAT TTCCAACTAT TATGGCGTCT CTGGGTTCCA GACCACTGAG 
CACTTTCTGA CGGCAGTGGC CCACCGTTTG GGGAAGAAGA AGAAGGGAGG CTTATATAGT 
CAGGAACAGG CGGCCAAAGC TGTCCTAGCT GACTGGGTGA GCGGGAAGAT CAGCTTCTAT 
ATACCACCAC CAGCCACTCA CACTCTGCCC ACCCATCTCA GTGCTGAGAT CGTTAAGGAA 
ATGACCGAGG TCTTTGACAT CGAGGATACT GAGCAGGCCA ATGAAGACAC CATGGAATGC 
TTGGCCACCG GAGAATCTGA TGAGCTGTTG GGTGACACGG ACCCACTTGA AATGGAGATC 
AAGTTGCTCC ATTCTCCGAT GACGAAAATA GCAGATGCCA TTGAAAATAA AACCACCGTG 
TATAAGATTG GAGATCTCAC TGGGTATTGC ACCAATCCGA ACCGTCATCA GATGGGGTGG 
GCTAAACGCA ATGTGGACCA CCGCCCTAAG AGCAACAGTA TGGTGGATGT CTGCTCAGTG 
GACCGCCGCT CAGTGCTGCA GAGGATCATG GAGACGGACC CCCTGCAACA GGGCCAGGCT 
CTGGCATCTG CCCTGAAAAA TAAGAAGAAG ATGCAGAAAC GTGCAGATAA AATCGCCAGC 
AAGCTGTCTG ATTCCATGAT GTCTGCTCTC GACCTCTCTG GCAATGCTGA TGATGGTGTT 
GGTGACTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Leucine Zipper Down-regulated in Cancer-1 (LDOC1) interacts with Guanine nucleotide binding protein-like 3-like (GNL3L) to modulate Nuclear Factor-kappa B (NF-?B) signaling during cell proliferation.
Cell cycle (Georgetown, Tex.)15(23)3251-3267(2016 Dec)
Thoompumkal IJ,Rehna K,Anbarasu K,Mahalingam S

GNL3L Is a Nucleo-Cytoplasmic Shuttling Protein: Role in Cell Cycle Regulation.
PloS one10(8)e0135845(2015)
Thoompumkal IJ,Subba Rao MR,Kumaraswamy A,Krishnan R,Mahalingam S

Nucleostemin and GNL3L exercise distinct functions in genome protection and ribosome synthesis, respectively.
Journal of cell science127(Pt 10)2302-12(2014 May)
Lin T,Meng L,Lin TC,Wu LJ,Pederson T,Tsai RY

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
Cell149(6)1393-406(2012 Jun)
Castello A,Fischer B,Eichelbaum K,Horos R,Beckmann BM,Strein C,Davey NE,Humphreys DT,Preiss T,Steinmetz LM,Krijgsveld J,Hentze MW

Continual expression throughout the cell cycle and downregulation upon adipogenic differentiation makes nucleostemin a vital human MSC proliferation marker.
Stem cell reviews7(2)413-24(2011 Jun)
Oktar PA,Yildirim S,Balci D,Can A

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GNL3L cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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