MAGEL2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	MAGEL2
Entrez Gene ID	54551
Full Name	MAGE family member L2
Synonyms	NDNL1,PWLS,SHFYNG,nM15
General protein information	Preferred Names MAGE family member L2 Names MAGE-like protein 2 melanoma antigen family L2 necdin-like protein 1 protein nM15
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 15 Map Location: 15q11.2
Summary	Prader-Willi syndrome (PWS) is caused by the loss of expression of imprinted genes in chromosome 15q11-q13 region. Affected individuals exhibit neonatal hypotonia, developmental delay, and childhood-onset obesity. Necdin (NDN), a gene involved in the terminal differentiation of neurons, localizes to this region of the genome and has been implicated as one of the genes responsible for the etiology of PWS. This gene is structurally similar to NDN, is also localized to the PWS chromosomal region, and is paternally imprinted, suggesting a possible role for it in PWS. [provided by RefSeq, Oct 2010].
Disorder MIM:	605283
Disorder Html:	Schaaf-Yang syndrome, 615547 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_019066.5	NP_061939.3	MAGE-like protein 2
NM_019066.4	NP_061939.3	MAGE-like protein 2

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	LOC100684492	XP_003434387.1
Rattus norvegicus (Norway rat)	Magel2	XP_001054803.2
Homo sapiens (human)	MAGEL2	NP_061939.3
	MAGEL2	XP_001114423.2
Mus musculus (house mouse)	Magel2	NP_038807.4
Bos taurus (cattle)	MAGEL2	XP_002696517.1

Gene Ontology
Bibliography

Related articles in PubMed

A genetic locus for paranoia.
Crespi B, Read S, Salminen I, Hurd P
Biology letters14(1)(2018 Jan)

A De Novo Nonsense Mutation in MAGEL2 in a Patient Initially Diagnosed as Opitz-C: Similarities Between Schaaf-Yang and Opitz-C Syndromes.
Urreizti R, Cueto-Gonzalez AM, Franco-Valls H, Mort-Farre S, Roca-Ayats N, Ponomarenko J, Cozzuto L, Company C, Bosio M, Ossowski S, Montfort M, Hecht J, Tizzano EF, Cormand B, Vilageliu L, Opitz JM, Neri G, Grinberg D, Balcells S
Scientific reports744138(2017 Mar)

The phenotypic spectrum of Schaaf-Yang syndrome: 18 new affected individuals from 14 families.
Fountain MD, Aten E, Cho MT, Juusola J, Walkiewicz MA, Ray JW, Xia F, Yang Y, Graham BH, Bacino CA, Potocki L, van Haeringen A, Ruivenkamp CA, Mancias P, Northrup H, Kukolich MK, Weiss MM, van Ravenswaaij-Arts CM, Mathijssen IB, Levesque S, Meeks N, Rosenfeld JA, Lemke D, Hamosh A, Lewis SK, Race S, Stewart LL, Hay B, Lewis AM, Guerreiro RL, Bras JT, Martins MP, Derksen-Lubsen G, Peeters E, Stumpel C, Stegmann S, Bok LA, Santen GW, Schaaf CP
Genetics in medicine : official journal of the American College of Medical Genetics19(1)45-52(2017 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

This study provides strong evidence for the pathogenicity of truncating mutations of the paternal allele of MAGEL2, refines the associated clinical phenotypes, and highlights implications for genetic counseling for affected families
Title: The phenotypic spectrum of Schaaf-Yang syndrome: 18 new affected individuals from 14 families.

Truncating Mutations of MAGEL2, a Gene within the Prader-Willi Locus, Are Responsible for Severe Arthrogryposis.
Title: Truncating Mutations of MAGEL2, a Gene within the Prader-Willi Locus, Are Responsible for Severe Arthrogryposis.

A similar progressive loss of leptin sensitivity caused by loss of MAGEL2 in children with Prader-Willi syndrome could explain the delayed onset of increased appetite and weight gain in this complex disorder.
Title: Progressive postnatal decline in leptin sensitivity of arcuate hypothalamic neurons in the Magel2-null mouse model of Prader-Willi syndrome.

MAGEL2 is a new gene causing complex autism spectrum disorder and MAGEL2 loss of function can contribute to several aspects of the Prader-Willi syndrome phenotype.
Title: Truncating mutations of MAGEL2 cause Prader-Willi phenotypes and autism.

These findings provide a cellular and molecular function for MAGE-L2-TRIM27 in retrograde transport, including an unappreciated role of K63-linked ubiquitination and identification of an activating signal of the WASH regulatory complex.
Title: Regulation of WASH-dependent actin polymerization and protein trafficking by ubiquitination.

The following MAGEL2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MAGEL2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu20638	NM_019066.5 Latest version!	Homo sapiens MAGE family member L2 (MAGEL2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$881.30 $1259.00
View Old Accession Versions >>
OHu20638	NM_019066.4	Homo sapiens MAGE family member L2 (MAGEL2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$881.30 $1259.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MAGEL2 ( NM_019066.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_061939.3 Homo sapiens MAGE family member L2 (MAGEL2), mRNA.

Price & Availability↑

CloneID	OHu20638
Clone ID Related Accession (Same CDS sequence)	NM_019066.5 , NM_019066.4
Accession Version	NM_019066.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3750bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-30
Organism	Homo sapiens(human)
Product	MAGE-like protein 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC124309.7. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_019066.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##RefSeq-Attributes-START## imprinted gene :: PMID: 10556298, 10915770 MANE Ensembl match :: ENST00000650528.1/ ENSP00000497810.1 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTCGCAGC TAAGTAAGAA TCTGGGTGAC TCGAGTCCTC CGGCGGAGGC CCCGAAGCCG 
CCTGTCTATA GCCGCCCTAC GGTTCTGATG CGGGCCCCGC CCGCTTCCTC CCGGGCTCCG 
CCAGTCCCTT GGGATCCACC TCCAATTGAC TTGCAGGCTT CATTGGCCGC TTGGCAGGCA 
CCTCAGCCTG CCTGGGAGGC CCCACAGGGC CAGCTGCCCG CCCCGGTGGT TCCGATGACC 
CAGCCTCCTG CCCTAGGGGG CCCGATAGTC CCGGCTCCCC CGCTGGGGGG CCCGATGGGT 
AAGCCTCCGA CTCCCGGGGT CCTGATGGTG CATCCTCCAC CTCCGGGAGC CCCGATGGCC 
CAGCCTCCGA CCCCGGGAGT CCTGATGGTG CATCCTTCAG CTCCCGGAGC TCCCATGGCC 
CATCCTCCTC CTCCGGGGAC CCCAATGTCC CACCCTCCCC CTCCGGGGAC CCCAATGGCC 
CATCCTCCTC CTCCGGGGAC CCCGATGGCC CATCCTCCTC CTCCGGGGAC CCCGATGGTG 
CATCCTCCTC CTCCGGGGAC CCCGATGGCT CATCCTCCCC CTCCGGGGAC ACCGATGGCT 
CATCCTCCCC CTCCGGGGAC ACCGATGGCT CATCCTCCAC CTCCGGGGAC ACCGATGGCT 
CATCCTCCCC CTCCGGGTAC ACCGATGGCC CAGCCTCCAG CTCCGGGAGT CCTGATGGCC 
CAGCCTCTGA CTCCGGGAGT CCTGATGGTC CAGCCTGCTG CTCCGGGAGC ACCGATGGTC 
CAGCCGCCTC CAGCAGCCAT GATGACCCAG CCTCAGCCTT CAGGAGCACC GATGGCCAAG 
CCTCCAGGTC CAGGAGTCCT GATGATTCAT CCTCCAGGTG CGAGAGCTCC GATGACCCAG 
CCTCCAGCTT CAGGAGCACC GATGGCACAG CCGGCGGCCC CACCTGCACA GCCGATGGCC 
CCACCTGCAC AGCCGATGGC TTCTTGGGCC CCGCAGGCTC AGCCTCTGAT CCTGCAAATC 
CAGTCTCAAG TTATAAGGGC TCCTCCGCAG GTTCCCCAGG GCCCGCAGGC ACCCCCAGCG 
CAGCTAGCCA CACCCCCGGG CTGGCAGGCG ACCTCGCCAG GATGGCAGGC CACGCAGCAA 
GGCTGGCAGG CCACTCCCCT GACTTGGCAG ACCACGCAGG TCACCTGGCA GGCACCAGCC 
GTTACCTGGC AGGTGCCGCC GCCCATGCGC CAGGGGCCCC CGCCCATCCG CCCTGGCCCA 
CCACCCATCC GCCCTGGCCC ACCACCGGTG CGACAGGCCC CACCGCTGAT CCGCCAGGCC 
CCACCGGTGA TCCGCCAGGC CCCACCCGTG ATCCGCCAGG CCCCACCCGT GATCCGCCAG 
GCCCCCGCTG TGATCCGCCA GGCCCCACCT GTGATCCGCC AGGCCCCACC TGTGATCCGC 
CAGGCTCCAC CTGTGATCCG CCAGGCCCCG CCGCTGATCC GCCAGGCGCC GCCGCCCATC 
CGACCTGCCC CACAGGTCCT GGCCACCCAG CCACCGCTCT GGCAGGCCCT GCCACCCCCA 
CCTCCACTGC GGCAGGCCCC GCAGGCTAGG CTGCCGGCCC CGCAGGTGCA GGCGGCGCCG 
CAGGTGCCTA CGGCCCCACC TGCTACGCAG GTACCCGCGG CGCCGCCCGC TGGCCCGCAG 
GTGCCCCAGC CTGTGCTGCC GGCCCCGCTG TCTGCCCCAC TGTCTGCCCC GCAGGCTGTG 
CACTGCCCTT CCATCATCTG GCAGGCCCCC AAAGGTCAGC CCCCGGTGCC ACACGAGATT 
CCAACGTCAA TGGAATTCCA GGAGGTGCAG CAGACACAGG CGCTGGCCTG GCAGGCCCAG 
AAGGCCCCCA CTCACATCTG GCAGCCCCTG CCTGCCCAGG AGGCCCAGAG GCAGGCTCCC 
CCCTTGGTCC AGCTGGAGCA GCCCTTTCAG GGAGCCCCGC CCTCCCAAAA AGCCGTGCAA 
ATCCAGCTAC CCCCCCAGCA GGCCCAGGCA TCGGGTCCGC AAGCGGAGGT GCCCACACTG 
CCGCTCCAGC CTTCCTGGCA GGCACCGCCT GCAGTCTTGC AGGCCCAGCC CGGACCCCCG 
GTAGCAGCGG CAAATTTTCC CCTGGGCTCC GCTAAATCAT TGATGACTCC ATCAGGAGAA 
TGCAGGGCCT CTTCTATAGA CCGCAGGGGC TCCTCTAAAG AGCGCAGGAC CTCCTCGAAG 
GAGCGCAGGG CCCCTTCAAA AGACCGCATG ATCTTTGCTG CCACCTTCTG TGCTCCCAAG 
GCAGTGTCAG CTGCGCGAGC ACACCTGCCA GCTGCCTGGA AAAACCTGCC TGCCACACCG 
GAGACCTTTG CTCCCTCCTC AAGTGTCTTC CCAGCTACCT CCCAGTTTCA GCCTGCCTCT 
CTGAATGCCT TTAAAGGCCC CTCTGCTGCC TCAGAGACCC CAAAGTCACT GCCATATGCT 
CTGCAGGATC CCTTTGCCTG TGTAGAGGCC CTGCCTGCAG TTCCATGGGT CCCACAGCCC 
AATATGAATG CCTCAAAGGC ATCGCAGGCA GTGCCCACCT TCCTGATGGC TACAGCAGCT 
GCCCCCCAGG CAACTGCCAC CACTCAAGAG GCCTCCAAGA CCTCCGTCGA GCCGCCACGC 
CGCTCCGGCA AGGCCACCCG GAAGAAGAAG CATCTGGAAG CCCAAGAGGA CAGCCGTGGC 
CACACGCTAG CCTTTCATGA CTGGCAGGGC CCAAGGCCCT GGGAGAATCT AAATCTGAGT 
GACTGGGAGG TCCAAAGCCC TATCCAGGTC TCGGGTGACT GGGAGCACCC AAACACCCCC 
CGTGGCCTGA GTGGTTGGGA GGGCCCTAGC ACCTCCAGGA TCCTGAGTGG CTGGGAAGGG 
CCCAGCGCAT CCTGGGCCCT GAGTGCCTGG GAGGGCCCGA GCACCTCCAG GGCCCTGGGT 
CTCTCTGAAA GCCCAGGGAG CTCTCTGCCC GTAGTTGTGT CTGAGGTCGC AAGTGTCTCT 
CCGGGATCCA GTGCCACCCA GGATAATTCC AAGGTGGAGG CACAGCCCTT GTCTCCCTTG 
GATGAGAGGG CAAATGCGTT GGTGCAGTTC CTCTTAGTCA AGGACCAAGC CAAGGTGCCT 
GTCCAGCGCT CGGAGATGGT GAAAGTCATC CTCCGAGAGT ATAAAGATGA GTGCTTAGAT 
ATCATCAACC GTGCCAACAA TAAGCTGGAG TGTGCCTTTG GTTATCAATT GAAAGAAATT 
GATACCAAAA ACCACGCCTA TATTATCATC AACAAGCTGG GCTACCATAC AGGGAATTTG 
GTGGCATCCT ATTTAGACAG GCCCAAGTTT GGCCTTCTGA TGGTGGTCTT GAGCCTCATC 
TTTATGAAAG GCAACTGTGT CAGGGAGGAT CTGATCTTTA ATTTTCTGTT CAAGTTAGGG 
TTGGATGTCC GGGAGACAAA CGGTCTCTTT GGAAATACTA AGAAGCTCAT CACCGAAGTG 
TTTGTCAGGC AGAAGTACCT AGAGTACAGG CGAATCCCTT ACACTGAGCC CGCAGAGTAT 
GAGTTCCTCT GGGGCCCTCG AGCATTCCTG GAAACCAGCA AGATGCTTGT CCTGAGGTTT 
TTGGCCAAGC TCCATAAGAA AGATCCACAG AGCTGGCCAT TCCATTACCT TGAAGCGCTC 
GCAGAGTGTG AGTGGGAAGA CACAGATGAG GATGAACCTG ACACCGGTGA CAGTGCCCAC 
GGCCCCACCA GCAGGCCCCC TCCCCGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_061939.3
CDS	126..3875
Translation	MSQLSKNLGDSSPPAEAPKPPVYSRPTVLMRAPPASSRAPPVPWDPPPIDLQASLAAWQAPQPAWEAPQGQLPAPVVPMTQPPALGGPIVPAPPLGGPMGKPPTPGVLMVHPPPPGAPMAQPPTPGVLMVHPSAPGAPMAHPPPPGTPMSHPPPPGTPMAHPPPPGTPMAHPPPPGTPMVHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAQPPAPGVLMAQPLTPGVLMVQPAAPGAPMVQPPPAAMMTQPQPSGAPMAKPPGPGVLMIHPPGARAPMTQPPASGAPMAQPAAPPAQPMAPPAQPMASWAPQAQPLILQIQSQVIRAPPQVPQGPQAPPAQLATPPGWQATSPGWQATQQGWQATPLTWQTTQVTWQAPAVTWQVPPPMRQGPPPIRPGPPPIRPGPPPVRQAPPLIRQAPPVIRQAPPVIRQAPPVIRQAPAVIRQAPPVIRQAPPVIRQAPPVIRQAPPLIRQAPPPIRPAPQVLATQPPLWQALPPPPPLRQAPQARLPAPQVQAAPQVPTAPPATQVPAAPPAGPQVPQPVLPAPLSAPLSAPQAVHCPSIIWQAPKGQPPVPHEIPTSMEFQEVQQTQALAWQAQKAPTHIWQPLPAQEAQRQAPPLVQLEQPFQGAPPSQKAVQIQLPPQQAQASGPQAEVPTLPLQPSWQAPPAVLQAQPGPPVAAANFPLGSAKSLMTPSGECRASSIDRRGSSKERRTSSKERRAPSKDRMIFAATFCAPKAVSAARAHLPAAWKNLPATPETFAPSSSVFPATSQFQPASLNAFKGPSAASETPKSLPYALQDPFACVEALPAVPWVPQPNMNASKASQAVPTFLMATAAAPQATATTQEASKTSVEPPRRSGKATRKKKHLEAQEDSRGHTLAFHDWQGPRPWENLNLSDWEVQSPIQVSGDWEHPNTPRGLSGWEGPSTSRILSGWEGPSASWALSAWEGPSTSRALGLSESPGSSLPVVVSEVASVSPGSSATQDNSKVEAQPLSPLDERANALVQFLLVKDQAKVPVQRSEMVKVILREYKDECLDIINRANNKLECAFGYQLKEIDTKNHAYIIINKLGYHTGNLVASYLDRPKFGLLMVVLSLIFMKGNCVREDLIFNFLFKLGLDVRETNGLFGNTKKLITEVFVRQKYLEYRRIPYTEPAEYEFLWGPRAFLETSKMLVLRFLAKLHKKDPQSWPFHYLEALAECEWEDTDEDEPDTGDSAHGPTSRPPPR

Target ORF information:

RefSeq Version	NM_019066.5
Organism	Homo sapiens(human)
Definition	Homo sapiens MAGE family member L2 (MAGEL2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019066.5

ORF Insert Sequence:

ATGTCGCAGC TAAGTAAGAA TCTGGGTGAC TCGAGTCCTC CGGCGGAGGC CCCGAAGCCG 
CCTGTCTATA GCCGCCCTAC GGTTCTGATG CGGGCCCCGC CCGCTTCCTC CCGGGCTCCG 
CCAGTCCCTT GGGATCCACC TCCAATTGAC TTGCAGGCTT CATTGGCCGC TTGGCAGGCA 
CCTCAGCCTG CCTGGGAGGC CCCACAGGGC CAGCTGCCCG CCCCGGTGGT TCCGATGACC 
CAGCCTCCTG CCCTAGGGGG CCCGATAGTC CCGGCTCCCC CGCTGGGGGG CCCGATGGGT 
AAGCCTCCGA CTCCCGGGGT CCTGATGGTG CATCCTCCAC CTCCGGGAGC CCCGATGGCC 
CAGCCTCCGA CCCCGGGAGT CCTGATGGTG CATCCTTCAG CTCCCGGAGC TCCCATGGCC 
CATCCTCCTC CTCCGGGGAC CCCAATGTCC CACCCTCCCC CTCCGGGGAC CCCAATGGCC 
CATCCTCCTC CTCCGGGGAC CCCGATGGCC CATCCTCCTC CTCCGGGGAC CCCGATGGTG 
CATCCTCCTC CTCCGGGGAC CCCGATGGCT CATCCTCCCC CTCCGGGGAC ACCGATGGCT 
CATCCTCCCC CTCCGGGGAC ACCGATGGCT CATCCTCCAC CTCCGGGGAC ACCGATGGCT 
CATCCTCCCC CTCCGGGTAC ACCGATGGCC CAGCCTCCAG CTCCGGGAGT CCTGATGGCC 
CAGCCTCTGA CTCCGGGAGT CCTGATGGTC CAGCCTGCTG CTCCGGGAGC ACCGATGGTC 
CAGCCGCCTC CAGCAGCCAT GATGACCCAG CCTCAGCCTT CAGGAGCACC GATGGCCAAG 
CCTCCAGGTC CAGGAGTCCT GATGATTCAT CCTCCAGGTG CGAGAGCTCC GATGACCCAG 
CCTCCAGCTT CAGGAGCACC GATGGCACAG CCGGCGGCCC CACCTGCACA GCCGATGGCC 
CCACCTGCAC AGCCGATGGC TTCTTGGGCC CCGCAGGCTC AGCCTCTGAT CCTGCAAATC 
CAGTCTCAAG TTATAAGGGC TCCTCCGCAG GTTCCCCAGG GCCCGCAGGC ACCCCCAGCG 
CAGCTAGCCA CACCCCCGGG CTGGCAGGCG ACCTCGCCAG GATGGCAGGC CACGCAGCAA 
GGCTGGCAGG CCACTCCCCT GACTTGGCAG ACCACGCAGG TCACCTGGCA GGCACCAGCC 
GTTACCTGGC AGGTGCCGCC GCCCATGCGC CAGGGGCCCC CGCCCATCCG CCCTGGCCCA 
CCACCCATCC GCCCTGGCCC ACCACCGGTG CGACAGGCCC CACCGCTGAT CCGCCAGGCC 
CCACCGGTGA TCCGCCAGGC CCCACCCGTG ATCCGCCAGG CCCCACCCGT GATCCGCCAG 
GCCCCCGCTG TGATCCGCCA GGCCCCACCT GTGATCCGCC AGGCCCCACC TGTGATCCGC 
CAGGCTCCAC CTGTGATCCG CCAGGCCCCG CCGCTGATCC GCCAGGCGCC GCCGCCCATC 
CGACCTGCCC CACAGGTCCT GGCCACCCAG CCACCGCTCT GGCAGGCCCT GCCACCCCCA 
CCTCCACTGC GGCAGGCCCC GCAGGCTAGG CTGCCGGCCC CGCAGGTGCA GGCGGCGCCG 
CAGGTGCCTA CGGCCCCACC TGCTACGCAG GTACCCGCGG CGCCGCCCGC TGGCCCGCAG 
GTGCCCCAGC CTGTGCTGCC GGCCCCGCTG TCTGCCCCAC TGTCTGCCCC GCAGGCTGTG 
CACTGCCCTT CCATCATCTG GCAGGCCCCC AAAGGTCAGC CCCCGGTGCC ACACGAGATT 
CCAACGTCAA TGGAATTCCA GGAGGTGCAG CAGACACAGG CGCTGGCCTG GCAGGCCCAG 
AAGGCCCCCA CTCACATCTG GCAGCCCCTG CCTGCCCAGG AGGCCCAGAG GCAGGCTCCC 
CCCTTGGTCC AGCTGGAGCA GCCCTTTCAG GGAGCCCCGC CCTCCCAAAA AGCCGTGCAA 
ATCCAGCTAC CCCCCCAGCA GGCCCAGGCA TCGGGTCCGC AAGCGGAGGT GCCCACACTG 
CCGCTCCAGC CTTCCTGGCA GGCACCGCCT GCAGTCTTGC AGGCCCAGCC CGGACCCCCG 
GTAGCAGCGG CAAATTTTCC CCTGGGCTCC GCTAAATCAT TGATGACTCC ATCAGGAGAA 
TGCAGGGCCT CTTCTATAGA CCGCAGGGGC TCCTCTAAAG AGCGCAGGAC CTCCTCGAAG 
GAGCGCAGGG CCCCTTCAAA AGACCGCATG ATCTTTGCTG CCACCTTCTG TGCTCCCAAG 
GCAGTGTCAG CTGCGCGAGC ACACCTGCCA GCTGCCTGGA AAAACCTGCC TGCCACACCG 
GAGACCTTTG CTCCCTCCTC AAGTGTCTTC CCAGCTACCT CCCAGTTTCA GCCTGCCTCT 
CTGAATGCCT TTAAAGGCCC CTCTGCTGCC TCAGAGACCC CAAAGTCACT GCCATATGCT 
CTGCAGGATC CCTTTGCCTG TGTAGAGGCC CTGCCTGCAG TTCCATGGGT CCCACAGCCC 
AATATGAATG CCTCAAAGGC ATCGCAGGCA GTGCCCACCT TCCTGATGGC TACAGCAGCT 
GCCCCCCAGG CAACTGCCAC CACTCAAGAG GCCTCCAAGA CCTCCGTCGA GCCGCCACGC 
CGCTCCGGCA AGGCCACCCG GAAGAAGAAG CATCTGGAAG CCCAAGAGGA CAGCCGTGGC 
CACACGCTAG CCTTTCATGA CTGGCAGGGC CCAAGGCCCT GGGAGAATCT AAATCTGAGT 
GACTGGGAGG TCCAAAGCCC TATCCAGGTC TCGGGTGACT GGGAGCACCC AAACACCCCC 
CGTGGCCTGA GTGGTTGGGA GGGCCCTAGC ACCTCCAGGA TCCTGAGTGG CTGGGAAGGG 
CCCAGCGCAT CCTGGGCCCT GAGTGCCTGG GAGGGCCCGA GCACCTCCAG GGCCCTGGGT 
CTCTCTGAAA GCCCAGGGAG CTCTCTGCCC GTAGTTGTGT CTGAGGTCGC AAGTGTCTCT 
CCGGGATCCA GTGCCACCCA GGATAATTCC AAGGTGGAGG CACAGCCCTT GTCTCCCTTG 
GATGAGAGGG CAAATGCGTT GGTGCAGTTC CTCTTAGTCA AGGACCAAGC CAAGGTGCCT 
GTCCAGCGCT CGGAGATGGT GAAAGTCATC CTCCGAGAGT ATAAAGATGA GTGCTTAGAT 
ATCATCAACC GTGCCAACAA TAAGCTGGAG TGTGCCTTTG GTTATCAATT GAAAGAAATT 
GATACCAAAA ACCACGCCTA TATTATCATC AACAAGCTGG GCTACCATAC AGGGAATTTG 
GTGGCATCCT ATTTAGACAG GCCCAAGTTT GGCCTTCTGA TGGTGGTCTT GAGCCTCATC 
TTTATGAAAG GCAACTGTGT CAGGGAGGAT CTGATCTTTA ATTTTCTGTT CAAGTTAGGG 
TTGGATGTCC GGGAGACAAA CGGTCTCTTT GGAAATACTA AGAAGCTCAT CACCGAAGTG 
TTTGTCAGGC AGAAGTACCT AGAGTACAGG CGAATCCCTT ACACTGAGCC CGCAGAGTAT 
GAGTTCCTCT GGGGCCCTCG AGCATTCCTG GAAACCAGCA AGATGCTTGT CCTGAGGTTT 
TTGGCCAAGC TCCATAAGAA AGATCCACAG AGCTGGCCAT TCCATTACCT TGAAGCGCTC 
GCAGAGTGTG AGTGGGAAGA CACAGATGAG GATGAACCTG ACACCGGTGA CAGTGCCCAC 
GGCCCCACCA GCAGGCCCCC TCCCCGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MAGEL2 ( NM_019066.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_061939.3 Homo sapiens MAGE family member L2 (MAGEL2), mRNA.

Price & Availability↑

CloneID	OHu20638
Clone ID Related Accession (Same CDS sequence)	NM_019066.5 , NM_019066.4
Accession Version	NM_019066.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3750bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-10
Organism	Homo sapiens(human)
Product	MAGE-like protein 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC124309.7. This sequence is a reference standard in the RefSeqGene project. On Sep 12, 2009 this sequence version replaced NM_019066.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##RefSeq-Attributes-START## imprinted gene :: PMID: 10556298, 10915770 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGTCGCAGC TAAGTAAGAA TCTGGGTGAC TCGAGTCCTC CGGCGGAGGC CCCGAAGCCG 
CCTGTCTATA GCCGCCCTAC GGTTCTGATG CGGGCCCCGC CCGCTTCCTC CCGGGCTCCG 
CCAGTCCCTT GGGATCCACC TCCAATTGAC TTGCAGGCTT CATTGGCCGC TTGGCAGGCA 
CCTCAGCCTG CCTGGGAGGC CCCACAGGGC CAGCTGCCCG CCCCGGTGGT TCCGATGACC 
CAGCCTCCTG CCCTAGGGGG CCCGATAGTC CCGGCTCCCC CGCTGGGGGG CCCGATGGGT 
AAGCCTCCGA CTCCCGGGGT CCTGATGGTG CATCCTCCAC CTCCGGGAGC CCCGATGGCC 
CAGCCTCCGA CCCCGGGAGT CCTGATGGTG CATCCTTCAG CTCCCGGAGC TCCCATGGCC 
CATCCTCCTC CTCCGGGGAC CCCAATGTCC CACCCTCCCC CTCCGGGGAC CCCAATGGCC 
CATCCTCCTC CTCCGGGGAC CCCGATGGCC CATCCTCCTC CTCCGGGGAC CCCGATGGTG 
CATCCTCCTC CTCCGGGGAC CCCGATGGCT CATCCTCCCC CTCCGGGGAC ACCGATGGCT 
CATCCTCCCC CTCCGGGGAC ACCGATGGCT CATCCTCCAC CTCCGGGGAC ACCGATGGCT 
CATCCTCCCC CTCCGGGTAC ACCGATGGCC CAGCCTCCAG CTCCGGGAGT CCTGATGGCC 
CAGCCTCTGA CTCCGGGAGT CCTGATGGTC CAGCCTGCTG CTCCGGGAGC ACCGATGGTC 
CAGCCGCCTC CAGCAGCCAT GATGACCCAG CCTCAGCCTT CAGGAGCACC GATGGCCAAG 
CCTCCAGGTC CAGGAGTCCT GATGATTCAT CCTCCAGGTG CGAGAGCTCC GATGACCCAG 
CCTCCAGCTT CAGGAGCACC GATGGCACAG CCGGCGGCCC CACCTGCACA GCCGATGGCC 
CCACCTGCAC AGCCGATGGC TTCTTGGGCC CCGCAGGCTC AGCCTCTGAT CCTGCAAATC 
CAGTCTCAAG TTATAAGGGC TCCTCCGCAG GTTCCCCAGG GCCCGCAGGC ACCCCCAGCG 
CAGCTAGCCA CACCCCCGGG CTGGCAGGCG ACCTCGCCAG GATGGCAGGC CACGCAGCAA 
GGCTGGCAGG CCACTCCCCT GACTTGGCAG ACCACGCAGG TCACCTGGCA GGCACCAGCC 
GTTACCTGGC AGGTGCCGCC GCCCATGCGC CAGGGGCCCC CGCCCATCCG CCCTGGCCCA 
CCACCCATCC GCCCTGGCCC ACCACCGGTG CGACAGGCCC CACCGCTGAT CCGCCAGGCC 
CCACCGGTGA TCCGCCAGGC CCCACCCGTG ATCCGCCAGG CCCCACCCGT GATCCGCCAG 
GCCCCCGCTG TGATCCGCCA GGCCCCACCT GTGATCCGCC AGGCCCCACC TGTGATCCGC 
CAGGCTCCAC CTGTGATCCG CCAGGCCCCG CCGCTGATCC GCCAGGCGCC GCCGCCCATC 
CGACCTGCCC CACAGGTCCT GGCCACCCAG CCACCGCTCT GGCAGGCCCT GCCACCCCCA 
CCTCCACTGC GGCAGGCCCC GCAGGCTAGG CTGCCGGCCC CGCAGGTGCA GGCGGCGCCG 
CAGGTGCCTA CGGCCCCACC TGCTACGCAG GTACCCGCGG CGCCGCCCGC TGGCCCGCAG 
GTGCCCCAGC CTGTGCTGCC GGCCCCGCTG TCTGCCCCAC TGTCTGCCCC GCAGGCTGTG 
CACTGCCCTT CCATCATCTG GCAGGCCCCC AAAGGTCAGC CCCCGGTGCC ACACGAGATT 
CCAACGTCAA TGGAATTCCA GGAGGTGCAG CAGACACAGG CGCTGGCCTG GCAGGCCCAG 
AAGGCCCCCA CTCACATCTG GCAGCCCCTG CCTGCCCAGG AGGCCCAGAG GCAGGCTCCC 
CCCTTGGTCC AGCTGGAGCA GCCCTTTCAG GGAGCCCCGC CCTCCCAAAA AGCCGTGCAA 
ATCCAGCTAC CCCCCCAGCA GGCCCAGGCA TCGGGTCCGC AAGCGGAGGT GCCCACACTG 
CCGCTCCAGC CTTCCTGGCA GGCACCGCCT GCAGTCTTGC AGGCCCAGCC CGGACCCCCG 
GTAGCAGCGG CAAATTTTCC CCTGGGCTCC GCTAAATCAT TGATGACTCC ATCAGGAGAA 
TGCAGGGCCT CTTCTATAGA CCGCAGGGGC TCCTCTAAAG AGCGCAGGAC CTCCTCGAAG 
GAGCGCAGGG CCCCTTCAAA AGACCGCATG ATCTTTGCTG CCACCTTCTG TGCTCCCAAG 
GCAGTGTCAG CTGCGCGAGC ACACCTGCCA GCTGCCTGGA AAAACCTGCC TGCCACACCG 
GAGACCTTTG CTCCCTCCTC AAGTGTCTTC CCAGCTACCT CCCAGTTTCA GCCTGCCTCT 
CTGAATGCCT TTAAAGGCCC CTCTGCTGCC TCAGAGACCC CAAAGTCACT GCCATATGCT 
CTGCAGGATC CCTTTGCCTG TGTAGAGGCC CTGCCTGCAG TTCCATGGGT CCCACAGCCC 
AATATGAATG CCTCAAAGGC ATCGCAGGCA GTGCCCACCT TCCTGATGGC TACAGCAGCT 
GCCCCCCAGG CAACTGCCAC CACTCAAGAG GCCTCCAAGA CCTCCGTCGA GCCGCCACGC 
CGCTCCGGCA AGGCCACCCG GAAGAAGAAG CATCTGGAAG CCCAAGAGGA CAGCCGTGGC 
CACACGCTAG CCTTTCATGA CTGGCAGGGC CCAAGGCCCT GGGAGAATCT AAATCTGAGT 
GACTGGGAGG TCCAAAGCCC TATCCAGGTC TCGGGTGACT GGGAGCACCC AAACACCCCC 
CGTGGCCTGA GTGGTTGGGA GGGCCCTAGC ACCTCCAGGA TCCTGAGTGG CTGGGAAGGG 
CCCAGCGCAT CCTGGGCCCT GAGTGCCTGG GAGGGCCCGA GCACCTCCAG GGCCCTGGGT 
CTCTCTGAAA GCCCAGGGAG CTCTCTGCCC GTAGTTGTGT CTGAGGTCGC AAGTGTCTCT 
CCGGGATCCA GTGCCACCCA GGATAATTCC AAGGTGGAGG CACAGCCCTT GTCTCCCTTG 
GATGAGAGGG CAAATGCGTT GGTGCAGTTC CTCTTAGTCA AGGACCAAGC CAAGGTGCCT 
GTCCAGCGCT CGGAGATGGT GAAAGTCATC CTCCGAGAGT ATAAAGATGA GTGCTTAGAT 
ATCATCAACC GTGCCAACAA TAAGCTGGAG TGTGCCTTTG GTTATCAATT GAAAGAAATT 
GATACCAAAA ACCACGCCTA TATTATCATC AACAAGCTGG GCTACCATAC AGGGAATTTG 
GTGGCATCCT ATTTAGACAG GCCCAAGTTT GGCCTTCTGA TGGTGGTCTT GAGCCTCATC 
TTTATGAAAG GCAACTGTGT CAGGGAGGAT CTGATCTTTA ATTTTCTGTT CAAGTTAGGG 
TTGGATGTCC GGGAGACAAA CGGTCTCTTT GGAAATACTA AGAAGCTCAT CACCGAAGTG 
TTTGTCAGGC AGAAGTACCT AGAGTACAGG CGAATCCCTT ACACTGAGCC CGCAGAGTAT 
GAGTTCCTCT GGGGCCCTCG AGCATTCCTG GAAACCAGCA AGATGCTTGT CCTGAGGTTT 
TTGGCCAAGC TCCATAAGAA AGATCCACAG AGCTGGCCAT TCCATTACCT TGAAGCGCTC 
GCAGAGTGTG AGTGGGAAGA CACAGATGAG GATGAACCTG ACACCGGTGA CAGTGCCCAC 
GGCCCCACCA GCAGGCCCCC TCCCCGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_061939.3
CDS	105..3854
Translation	MSQLSKNLGDSSPPAEAPKPPVYSRPTVLMRAPPASSRAPPVPWDPPPIDLQASLAAWQAPQPAWEAPQGQLPAPVVPMTQPPALGGPIVPAPPLGGPMGKPPTPGVLMVHPPPPGAPMAQPPTPGVLMVHPSAPGAPMAHPPPPGTPMSHPPPPGTPMAHPPPPGTPMAHPPPPGTPMVHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAQPPAPGVLMAQPLTPGVLMVQPAAPGAPMVQPPPAAMMTQPQPSGAPMAKPPGPGVLMIHPPGARAPMTQPPASGAPMAQPAAPPAQPMAPPAQPMASWAPQAQPLILQIQSQVIRAPPQVPQGPQAPPAQLATPPGWQATSPGWQATQQGWQATPLTWQTTQVTWQAPAVTWQVPPPMRQGPPPIRPGPPPIRPGPPPVRQAPPLIRQAPPVIRQAPPVIRQAPPVIRQAPAVIRQAPPVIRQAPPVIRQAPPVIRQAPPLIRQAPPPIRPAPQVLATQPPLWQALPPPPPLRQAPQARLPAPQVQAAPQVPTAPPATQVPAAPPAGPQVPQPVLPAPLSAPLSAPQAVHCPSIIWQAPKGQPPVPHEIPTSMEFQEVQQTQALAWQAQKAPTHIWQPLPAQEAQRQAPPLVQLEQPFQGAPPSQKAVQIQLPPQQAQASGPQAEVPTLPLQPSWQAPPAVLQAQPGPPVAAANFPLGSAKSLMTPSGECRASSIDRRGSSKERRTSSKERRAPSKDRMIFAATFCAPKAVSAARAHLPAAWKNLPATPETFAPSSSVFPATSQFQPASLNAFKGPSAASETPKSLPYALQDPFACVEALPAVPWVPQPNMNASKASQAVPTFLMATAAAPQATATTQEASKTSVEPPRRSGKATRKKKHLEAQEDSRGHTLAFHDWQGPRPWENLNLSDWEVQSPIQVSGDWEHPNTPRGLSGWEGPSTSRILSGWEGPSASWALSAWEGPSTSRALGLSESPGSSLPVVVSEVASVSPGSSATQDNSKVEAQPLSPLDERANALVQFLLVKDQAKVPVQRSEMVKVILREYKDECLDIINRANNKLECAFGYQLKEIDTKNHAYIIINKLGYHTGNLVASYLDRPKFGLLMVVLSLIFMKGNCVREDLIFNFLFKLGLDVRETNGLFGNTKKLITEVFVRQKYLEYRRIPYTEPAEYEFLWGPRAFLETSKMLVLRFLAKLHKKDPQSWPFHYLEALAECEWEDTDEDEPDTGDSAHGPTSRPPPR

Target ORF information:

RefSeq Version	NM_019066.4
Organism	Homo sapiens(human)
Definition	Homo sapiens MAGE family member L2 (MAGEL2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019066.4

ORF Insert Sequence:

ATGTCGCAGC TAAGTAAGAA TCTGGGTGAC TCGAGTCCTC CGGCGGAGGC CCCGAAGCCG 
CCTGTCTATA GCCGCCCTAC GGTTCTGATG CGGGCCCCGC CCGCTTCCTC CCGGGCTCCG 
CCAGTCCCTT GGGATCCACC TCCAATTGAC TTGCAGGCTT CATTGGCCGC TTGGCAGGCA 
CCTCAGCCTG CCTGGGAGGC CCCACAGGGC CAGCTGCCCG CCCCGGTGGT TCCGATGACC 
CAGCCTCCTG CCCTAGGGGG CCCGATAGTC CCGGCTCCCC CGCTGGGGGG CCCGATGGGT 
AAGCCTCCGA CTCCCGGGGT CCTGATGGTG CATCCTCCAC CTCCGGGAGC CCCGATGGCC 
CAGCCTCCGA CCCCGGGAGT CCTGATGGTG CATCCTTCAG CTCCCGGAGC TCCCATGGCC 
CATCCTCCTC CTCCGGGGAC CCCAATGTCC CACCCTCCCC CTCCGGGGAC CCCAATGGCC 
CATCCTCCTC CTCCGGGGAC CCCGATGGCC CATCCTCCTC CTCCGGGGAC CCCGATGGTG 
CATCCTCCTC CTCCGGGGAC CCCGATGGCT CATCCTCCCC CTCCGGGGAC ACCGATGGCT 
CATCCTCCCC CTCCGGGGAC ACCGATGGCT CATCCTCCAC CTCCGGGGAC ACCGATGGCT 
CATCCTCCCC CTCCGGGTAC ACCGATGGCC CAGCCTCCAG CTCCGGGAGT CCTGATGGCC 
CAGCCTCTGA CTCCGGGAGT CCTGATGGTC CAGCCTGCTG CTCCGGGAGC ACCGATGGTC 
CAGCCGCCTC CAGCAGCCAT GATGACCCAG CCTCAGCCTT CAGGAGCACC GATGGCCAAG 
CCTCCAGGTC CAGGAGTCCT GATGATTCAT CCTCCAGGTG CGAGAGCTCC GATGACCCAG 
CCTCCAGCTT CAGGAGCACC GATGGCACAG CCGGCGGCCC CACCTGCACA GCCGATGGCC 
CCACCTGCAC AGCCGATGGC TTCTTGGGCC CCGCAGGCTC AGCCTCTGAT CCTGCAAATC 
CAGTCTCAAG TTATAAGGGC TCCTCCGCAG GTTCCCCAGG GCCCGCAGGC ACCCCCAGCG 
CAGCTAGCCA CACCCCCGGG CTGGCAGGCG ACCTCGCCAG GATGGCAGGC CACGCAGCAA 
GGCTGGCAGG CCACTCCCCT GACTTGGCAG ACCACGCAGG TCACCTGGCA GGCACCAGCC 
GTTACCTGGC AGGTGCCGCC GCCCATGCGC CAGGGGCCCC CGCCCATCCG CCCTGGCCCA 
CCACCCATCC GCCCTGGCCC ACCACCGGTG CGACAGGCCC CACCGCTGAT CCGCCAGGCC 
CCACCGGTGA TCCGCCAGGC CCCACCCGTG ATCCGCCAGG CCCCACCCGT GATCCGCCAG 
GCCCCCGCTG TGATCCGCCA GGCCCCACCT GTGATCCGCC AGGCCCCACC TGTGATCCGC 
CAGGCTCCAC CTGTGATCCG CCAGGCCCCG CCGCTGATCC GCCAGGCGCC GCCGCCCATC 
CGACCTGCCC CACAGGTCCT GGCCACCCAG CCACCGCTCT GGCAGGCCCT GCCACCCCCA 
CCTCCACTGC GGCAGGCCCC GCAGGCTAGG CTGCCGGCCC CGCAGGTGCA GGCGGCGCCG 
CAGGTGCCTA CGGCCCCACC TGCTACGCAG GTACCCGCGG CGCCGCCCGC TGGCCCGCAG 
GTGCCCCAGC CTGTGCTGCC GGCCCCGCTG TCTGCCCCAC TGTCTGCCCC GCAGGCTGTG 
CACTGCCCTT CCATCATCTG GCAGGCCCCC AAAGGTCAGC CCCCGGTGCC ACACGAGATT 
CCAACGTCAA TGGAATTCCA GGAGGTGCAG CAGACACAGG CGCTGGCCTG GCAGGCCCAG 
AAGGCCCCCA CTCACATCTG GCAGCCCCTG CCTGCCCAGG AGGCCCAGAG GCAGGCTCCC 
CCCTTGGTCC AGCTGGAGCA GCCCTTTCAG GGAGCCCCGC CCTCCCAAAA AGCCGTGCAA 
ATCCAGCTAC CCCCCCAGCA GGCCCAGGCA TCGGGTCCGC AAGCGGAGGT GCCCACACTG 
CCGCTCCAGC CTTCCTGGCA GGCACCGCCT GCAGTCTTGC AGGCCCAGCC CGGACCCCCG 
GTAGCAGCGG CAAATTTTCC CCTGGGCTCC GCTAAATCAT TGATGACTCC ATCAGGAGAA 
TGCAGGGCCT CTTCTATAGA CCGCAGGGGC TCCTCTAAAG AGCGCAGGAC CTCCTCGAAG 
GAGCGCAGGG CCCCTTCAAA AGACCGCATG ATCTTTGCTG CCACCTTCTG TGCTCCCAAG 
GCAGTGTCAG CTGCGCGAGC ACACCTGCCA GCTGCCTGGA AAAACCTGCC TGCCACACCG 
GAGACCTTTG CTCCCTCCTC AAGTGTCTTC CCAGCTACCT CCCAGTTTCA GCCTGCCTCT 
CTGAATGCCT TTAAAGGCCC CTCTGCTGCC TCAGAGACCC CAAAGTCACT GCCATATGCT 
CTGCAGGATC CCTTTGCCTG TGTAGAGGCC CTGCCTGCAG TTCCATGGGT CCCACAGCCC 
AATATGAATG CCTCAAAGGC ATCGCAGGCA GTGCCCACCT TCCTGATGGC TACAGCAGCT 
GCCCCCCAGG CAACTGCCAC CACTCAAGAG GCCTCCAAGA CCTCCGTCGA GCCGCCACGC 
CGCTCCGGCA AGGCCACCCG GAAGAAGAAG CATCTGGAAG CCCAAGAGGA CAGCCGTGGC 
CACACGCTAG CCTTTCATGA CTGGCAGGGC CCAAGGCCCT GGGAGAATCT AAATCTGAGT 
GACTGGGAGG TCCAAAGCCC TATCCAGGTC TCGGGTGACT GGGAGCACCC AAACACCCCC 
CGTGGCCTGA GTGGTTGGGA GGGCCCTAGC ACCTCCAGGA TCCTGAGTGG CTGGGAAGGG 
CCCAGCGCAT CCTGGGCCCT GAGTGCCTGG GAGGGCCCGA GCACCTCCAG GGCCCTGGGT 
CTCTCTGAAA GCCCAGGGAG CTCTCTGCCC GTAGTTGTGT CTGAGGTCGC AAGTGTCTCT 
CCGGGATCCA GTGCCACCCA GGATAATTCC AAGGTGGAGG CACAGCCCTT GTCTCCCTTG 
GATGAGAGGG CAAATGCGTT GGTGCAGTTC CTCTTAGTCA AGGACCAAGC CAAGGTGCCT 
GTCCAGCGCT CGGAGATGGT GAAAGTCATC CTCCGAGAGT ATAAAGATGA GTGCTTAGAT 
ATCATCAACC GTGCCAACAA TAAGCTGGAG TGTGCCTTTG GTTATCAATT GAAAGAAATT 
GATACCAAAA ACCACGCCTA TATTATCATC AACAAGCTGG GCTACCATAC AGGGAATTTG 
GTGGCATCCT ATTTAGACAG GCCCAAGTTT GGCCTTCTGA TGGTGGTCTT GAGCCTCATC 
TTTATGAAAG GCAACTGTGT CAGGGAGGAT CTGATCTTTA ATTTTCTGTT CAAGTTAGGG 
TTGGATGTCC GGGAGACAAA CGGTCTCTTT GGAAATACTA AGAAGCTCAT CACCGAAGTG 
TTTGTCAGGC AGAAGTACCT AGAGTACAGG CGAATCCCTT ACACTGAGCC CGCAGAGTAT 
GAGTTCCTCT GGGGCCCTCG AGCATTCCTG GAAACCAGCA AGATGCTTGT CCTGAGGTTT 
TTGGCCAAGC TCCATAAGAA AGATCCACAG AGCTGGCCAT TCCATTACCT TGAAGCGCTC 
GCAGAGTGTG AGTGGGAAGA CACAGATGAG GATGAACCTG ACACCGGTGA CAGTGCCCAC 
GGCCCCACCA GCAGGCCCCC TCCCCGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A genetic locus for paranoia.
Biology letters14(1)(2018 Jan)
Crespi B,Read S,Salminen I,Hurd P

A De Novo Nonsense Mutation in MAGEL2 in a Patient Initially Diagnosed as Opitz-C: Similarities Between Schaaf-Yang and Opitz-C Syndromes.
Scientific reports744138(2017 Mar)
Urreizti R,Cueto-Gonzalez AM,Franco-Valls H,Mort-Farre S,Roca-Ayats N,Ponomarenko J,Cozzuto L,Company C,Bosio M,Ossowski S,Montfort M,Hecht J,Tizzano EF,Cormand B,Vilageliu L,Opitz JM,Neri G,Grinberg D,Balcells S

The phenotypic spectrum of Schaaf-Yang syndrome: 18 new affected individuals from 14 families.
Genetics in medicine : official journal of the American College of Medical Genetics19(1)45-52(2017 Jan)
Fountain MD,Aten E,Cho MT,Juusola J,Walkiewicz MA,Ray JW,Xia F,Yang Y,Graham BH,Bacino CA,Potocki L,van Haeringen A,Ruivenkamp CA,Mancias P,Northrup H,Kukolich MK,Weiss MM,van Ravenswaaij-Arts CM,Mathijssen IB,Levesque S,Meeks N,Rosenfeld JA,Lemke D,Hamosh A,Lewis SK,Race S,Stewart LL,Hay B,Lewis AM,Guerreiro RL,Bras JT,Martins MP,Derksen-Lubsen G,Peeters E,Stumpel C,Stegmann S,Bok LA,Santen GW,Schaaf CP

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MAGEL2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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