XRN1 gene cDNA ORF clone, Homo sapiens(human)

mRNA	Protein	Name
XM_017006640.1	XP_016862129.1	5'-3' exoribonuclease 1 isoform X2
XM_011512920.2	XP_011511222.1	5'-3' exoribonuclease 1 isoform X3
XM_017006641.1	XP_016862130.1	5'-3' exoribonuclease 1 isoform X4
NM_019001.5	NP_061874.3	5'-3' exoribonuclease 1 isoform a
NM_001282857.2	NP_001269786.1	5'-3' exoribonuclease 1 isoform c
NM_001282859.1	NP_001269788.1	5'-3' exoribonuclease 1 isoform d
NM_019001.4	NP_061874.3	5'-3' exoribonuclease 1 isoform a
XM_011512919.2	XP_011511221.1	5'-3' exoribonuclease 1 isoform X1
XM_011512922.2	XP_011511224.1	5'-3' exoribonuclease 1 isoform X5
NM_001282857.1	NP_001269786.1	5'-3' exoribonuclease 1 isoform c
XM_017006642.1	XP_016862131.1	5'-3' exoribonuclease 1 isoform X6
XM_006713673.2	XP_006713736.1	5'-3' exoribonuclease 1 isoform X7

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu05134	NM_001282859.1 Latest version!	Homo sapiens 5'-3' exoribonuclease 1 (XRN1), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu37992	XM_006713673.2 Latest version!	Homo sapiens 5'-3' exoribonuclease 1 (XRN1), transcript variant X8, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
OHu94296	XM_017006642.1 Latest version!	Homo sapiens 5'-3' exoribonuclease 1 (XRN1), transcript variant X7, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$727.30 $1039.00
OHu94294	XM_017006640.1 Latest version!	Homo sapiens 5'-3' exoribonuclease 1 (XRN1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	24-26	$951.30 $1359.00
OHu94295	XM_017006641.1 Latest version!	Homo sapiens 5'-3' exoribonuclease 1 (XRN1), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	24-26	$811.30 $1159.00
OHu08281	NM_001282857.2 Latest version!	Homo sapiens 5'-3' exoribonuclease 1 (XRN1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$951.30 $1359.00
OHu08448	NM_019001.5 Latest version!	Homo sapiens 5'-3' exoribonuclease 1 (XRN1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$923.30 $1319.00
OHu68345	XM_011512919.2 Latest version!	Homo sapiens 5'-3' exoribonuclease 1 (XRN1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$951.30 $1359.00
OHu68346	XM_011512920.2 Latest version!	Homo sapiens 5'-3' exoribonuclease 1 (XRN1), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$951.30 $1359.00
OHu68348	XM_011512922.2 Latest version!	Homo sapiens 5'-3' exoribonuclease 1 (XRN1), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$727.30 $1039.00
View Old Accession Versions >>
OHu08448	NM_019001.4	Homo sapiens 5'-3' exoribonuclease 1 (XRN1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$923.30 $1319.00
OHu08281	NM_001282857.1	Homo sapiens 5'-3' exoribonuclease 1 (XRN1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$951.30 $1359.00
Hide Old Accession Versions >>

XRN1 ( NM_001282859.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001269788.1 Homo sapiens 5'-3' exoribonuclease 1 (XRN1), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu05134
Clone ID Related Accession (Same CDS sequence)	NM_001282859.1
Accession Version	NM_001282859.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1380bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-15
Organism	Homo sapiens(human)
Product	5'-3' exoribonuclease 1 isoform d
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK096177.1 and BC039314.1. Transcript Variant: This variant (4) lacks several exons and its 3' terminal exon extends past a splice site that is used in variant 1. This results in a novel 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (d) has a shorter and distinct C-terminus, compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC039314.1, SRR1803614.183753.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGAGTCC CCAAGTTTTA CAGATGGATC TCAGAGCGGT ATCCCTGTCT CAGCGAAGTG 
GTGAAAGAGC ATCAGATTCC TGAATTTGAC AACTTGTACC TGGATATGAA TGGAATTATA 
CATCAGTGCT CCCATCCTAA TGATGATGAT GTTCACTTTA GAATTTCAGA TGATAAAATC 
TTTACTGATA TTTTTCACTA CCTGGAGGTG TTGTTTCGCA TTATTAAACC CAGGAAAGTG 
TTCTTTATGG CTGTAGATGG TGTGGCTCCT CGAGCAAAAA TGAACCAGCA GCGTGGGAGG 
CGTTTTAGGT CAGCAAAGGA GGCAGAAGAC AAAATTAAAA AGGCAATAGA GAAGGGAGAA 
ACTCTTCCTA CAGAGGCCAG ATTTGATTCC AACTGTATCA CACCAGGAAC TGAATTTATG 
GCCAGGTTAC ATGAACATCT GAAGTATTTT GTAAATATGA AAATTTCCAC AGACAAGTCA 
TGGCAAGGAG TTACCATCTA CTTCTCAGGC CATGAGACTC CTGGAGAAGG AGAGCATAAA 
ATCATGGAAT TTATCAGATC CGAGAAAGCA AAGCCAGATC ATGATCCAAA CACCAGACAC 
TGTCTTTATG GTTTAGATGC TGACTTGATT ATGCTTGGAT TAACAAGTCA TGAGGCACAT 
TTTTCTCTCT TAAGAGAAGA AGTTCGATTT GGTGGCAAAA AAACACAACG GGTATGTGCT 
CCAGAAGAAA CTACATTTCA CCTTCTACAC TTGTCTTTAA TGAGAGAGTA TATTGACTAT 
GAGTTTTCAG TATTAAAAGA AAAGATCACA TTTAAATATG ATATTGAAAG GATAATAGAT 
GATTGGATTT TGATGGGGTT TCTTGTTGGT AATGATTTTA TCCCTCATCT ACCTCATTTA 
CATATTAATC ATGATGCACT GCCTCTTCTT TATGGAACAT ATGTTACCAT CCTGCCAGAA 
CTTGGGGGTT ATATTAATGA AAGTGGGCAC CTCAACTTAC CTCGATTTGA GAAATACCTT 
GTGAAACTAT CAGATTTTGA TCGGGAGCAC TTCAGTGAAG TTTTTGTGGA CCTAAAATGG 
TTTGAAAGCA AAGTTGGTAA CAAGTACCTC AATGAAGCAG CAGGTGTCGC AGCAGAAGAA 
GCCAGGAACT ACAAGGAAAA GAAAAAGTTA AAGGGCCAGG AAAATTCTCT GTGTTGGACT 
GCTTTAGACA AAAATGAAGG CGAAATGATA ACTTCTAAGG ATAATTTAGA AGATGAGACT 
GAAGATGATG ACCTATTTGA AACTGAGTTT AGACAATATA AAAGAACATA TTACATGACG 
AAGATGGGGG TTGACGTAGT ATCTGAGTAC GTTTTTGCCA ATGCTTTTAT TTTAAAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001269788.1
CDS	119..1498
Translation	MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKIFTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKAIEKGETLPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHKIMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCAPEETTFHLLHLSLMREYIDYEFSVLKEKITFKYDIERIIDDWILMGFLVGNDFIPHLPHLHINHDALPLLYGTYVTILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKWFESKVGNKYLNEAAGVAAEEARNYKEKKKLKGQENSLCWTALDKNEGEMITSKDNLEDETEDDDLFETEFRQYKRTYYMTKMGVDVVSEYVFANAFILK

Target ORF information:

RefSeq Version	NM_001282859.1
Organism	Homo sapiens(human)
Definition	Homo sapiens 5'-3' exoribonuclease 1 (XRN1), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001282859.1

ORF Insert Sequence:

ATGGGAGTCC CCAAGTTTTA CAGATGGATC TCAGAGCGGT ATCCCTGTCT CAGCGAAGTG 
GTGAAAGAGC ATCAGATTCC TGAATTTGAC AACTTGTACC TGGATATGAA TGGAATTATA 
CATCAGTGCT CCCATCCTAA TGATGATGAT GTTCACTTTA GAATTTCAGA TGATAAAATC 
TTTACTGATA TTTTTCACTA CCTGGAGGTG TTGTTTCGCA TTATTAAACC CAGGAAAGTG 
TTCTTTATGG CTGTAGATGG TGTGGCTCCT CGAGCAAAAA TGAACCAGCA GCGTGGGAGG 
CGTTTTAGGT CAGCAAAGGA GGCAGAAGAC AAAATTAAAA AGGCAATAGA GAAGGGAGAA 
ACTCTTCCTA CAGAGGCCAG ATTTGATTCC AACTGTATCA CACCAGGAAC TGAATTTATG 
GCCAGGTTAC ATGAACATCT GAAGTATTTT GTAAATATGA AAATTTCCAC AGACAAGTCA 
TGGCAAGGAG TTACCATCTA CTTCTCAGGC CATGAGACTC CTGGAGAAGG AGAGCATAAA 
ATCATGGAAT TTATCAGATC CGAGAAAGCA AAGCCAGATC ATGATCCAAA CACCAGACAC 
TGTCTTTATG GTTTAGATGC TGACTTGATT ATGCTTGGAT TAACAAGTCA TGAGGCACAT 
TTTTCTCTCT TAAGAGAAGA AGTTCGATTT GGTGGCAAAA AAACACAACG GGTATGTGCT 
CCAGAAGAAA CTACATTTCA CCTTCTACAC TTGTCTTTAA TGAGAGAGTA TATTGACTAT 
GAGTTTTCAG TATTAAAAGA AAAGATCACA TTTAAATATG ATATTGAAAG GATAATAGAT 
GATTGGATTT TGATGGGGTT TCTTGTTGGT AATGATTTTA TCCCTCATCT ACCTCATTTA 
CATATTAATC ATGATGCACT GCCTCTTCTT TATGGAACAT ATGTTACCAT CCTGCCAGAA 
CTTGGGGGTT ATATTAATGA AAGTGGGCAC CTCAACTTAC CTCGATTTGA GAAATACCTT 
GTGAAACTAT CAGATTTTGA TCGGGAGCAC TTCAGTGAAG TTTTTGTGGA CCTAAAATGG 
TTTGAAAGCA AAGTTGGTAA CAAGTACCTC AATGAAGCAG CAGGTGTCGC AGCAGAAGAA 
GCCAGGAACT ACAAGGAAAA GAAAAAGTTA AAGGGCCAGG AAAATTCTCT GTGTTGGACT 
GCTTTAGACA AAAATGAAGG CGAAATGATA ACTTCTAAGG ATAATTTAGA AGATGAGACT 
GAAGATGATG ACCTATTTGA AACTGAGTTT AGACAATATA AAAGAACATA TTACATGACG 
AAGATGGGGG TTGACGTAGT ATCTGAGTAC GTTTTTGCCA ATGCTTTTAT TTTAAAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

XRN1 ( XM_006713673.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_006713736.1 Homo sapiens 5'-3' exoribonuclease 1 (XRN1), transcript variant X8, mRNA.

Price & Availability↑

CloneID	OHu37992
Clone ID Related Accession (Same CDS sequence)	XM_006713673.2
Accession Version	XM_006713673.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2787bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	5'-3' exoribonuclease 1 isoform X7
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced XM_006713673.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGAGTCC CCAAGTTTTA CAGATGGATC TCAGAGCGGT ATCCCTGTCT CAGCGAAGTG 
GTGAAAGAGC ATCAGATTCC TGAATTTGAC AACTTGTACC TGGATATGAA TGGAATTATA 
CATCAGTGCT CCCATCCTAA TGATGATGAT GTTCACTTTA GAATTTCAGA TGATAAAATC 
TTTACTGATA TTTTTCACTA CCTGGAGGTG TTGTTTCGCA TTATTAAACC CAGGAAAGTG 
TTCTTTATGG CTGTAGATGG TGTGGCTCCT CGAGCAAAAA TGAACCAGCA GCGTGGGAGG 
CGTTTTAGGT CAGCAAAGGA GGCAGAAGAC AAAATTAAAA AGGCAATAGA GAAGGGAGAA 
ACTCTTCCTA CAGAGGCCAG ATTTGATTCC AACTGTATCA CACCAGGAAC TGAATTTATG 
GCCAGGTTAC ATGAACATCT GAAGTATTTT GTAAATATGA AAATTTCCAC AGACAAGTCA 
TGGCAAGGAG TTACCATCTA CTTCTCAGGC CATGAGACTC CTGGAGAAGG AGAGCATAAA 
ATCATGGAAT TTATCAGATC CGAGAAAGCA AAGCCAGATC ATGATCCAAA CACCAGACAC 
TGTCTTTATG GTTTAGATGC TGACTTGATT ATGCTTGGAT TAACAAGTCA TGAGGCACAT 
TTTTCTCTCT TAAGAGAAGA AGTTCGATTT GGTGGCAAAA AAACACAACG GGTATGTGCT 
CCAGAAGAAA CTACATTTCA CCTTCTACAC TTGTCTTTAA TGAGAGAGTA TATTGACTAT 
GAGTTTTCAG TATTAAAAGA AAAGATCACA TTTAAATATG ATATTGAAAG GATAATAGAT 
GATTGGATTT TGATGGGGTT TCTTGTTGGT AATGATTTTA TCCCTCATCT ACCTCATTTA 
CATATTAATC ATGATGCACT GCCTCTTCTT TATGGAACAT ATGTTACCAT CCTGCCAGAA 
CTTGGGGGTT ATATTAATGA AAGTGGGCAC CTCAACTTAC CTCGATTTGA GAAATACCTT 
GTGAAACTAT CAGATTTTGA TCGGGAGCAC TTCAGTGAAG TTTTTGTGGA CCTAAAATGG 
TTTGAAAGCA AAGTTGGTAA CAAGTACCTC AATGAAGCAG CAGGTGTCGC AGCAGAAGAA 
GCCAGGAACT ACAAGGAAAA GAAAAAGTTA AAGGGCCAGG AAAATTCTCT GTGTTGGACT 
GCTTTAGACA AAAATGAAGG CGAAATGATA ACTTCTAAGG ATAATTTAGA AGATGAGACT 
GAAGATGATG ACCTATTTGA AACTGAGTTT AGACAATATA AAAGAACATA TTACATGACG 
AAGATGGGGG TTGACGTAGT ATCTGATGAC TTTCTGGCTG ATCAAGCTGC ATGTTATGTT 
CAGGCAATAC AGTGGATTTT GCACTATTAC TATCATGGAG TTCAGTCCTG GAGCTGGTAT 
TATCCTTATC ATTATGCACC TTTCCTGTCT GATATACACA ACATCAGTAC ACTCAAAATC 
CATTTTGAAC TAGGAAAACC TTTTAAGCCA TTTGAACAGC TTCTTGCTGT ACTTCCAGCA 
GCCAGCAAAA ATTTACTTCC TGCATGCTAC CAGCATTTGA TGACCAATGA AGACTCACCA 
ATTATAGAAT ATTACCCACC TGATTTTAAA ACTGACCTAA ATGGGAAACA ACAGGAATGG 
GAAGCTGTGG TGTTAATCCC TTTTATTGAT GAGAAGCGAT TATTGGAAGC CATGGAGACA 
TGTAACCACT CCCTCAAAAA GGAAGAGAGG AAAAGAAACC AACATAGTGA GTGCCTAATG 
TGCTGGTATG ATAGAGACAC AGAGTTTATC TATCCTTCTC CATGGCCAGA AAAGTTCCCT 
GCCATAGAAC GATGTTGTAC AAGGTATAAA ATAATATCCT TAGATGCTTG GCGTGTAGAC 
ATAAACAAAA ACAAAATAAC CAGAATTGAC CAGAAAGCAT TATATTTCTG TGGATTTCCT 
ACTCTGAAAC ACATCAGACA CAAATTTTTT TTGAAGAAAA GTGGTGTTCA AGTATTCCAG 
CAAAGCAGTC GTGGAGAAAA CATGATGTTG GAAATCTTAG TGGATGCAGA ATCAGATGAA 
CTTACCGTAG AAAATGTAGC TTCATCAGTG CTTGGAAAAT CTGTCTTTGT TAATTGGCCT 
CACCTTGAGG AAGCTAGAGT CGTGGCTGTA TCAGATGGAG AAACTAAGTT TTACTTGGAA 
GAACCTCCAG GAACACAGAA GCTTTATTCA GGAAGAACTG CCCCACCATC TAAAGTGGTT 
CATCTTGGAG ATAAAGAACA ATCTAACTGG GCAAAAGAAG TACAAGGAAT TTCAGAACAC 
TACCTGAGAA GAAAAGGAAT AATAATAAAT GAAACATCTG CAGTTGTGTA TGCTCAGTTA 
CTCACAGGTC GTAAATATCA AATAAATCAA AATGGTGAAG TTCGTCTAGA GAAACAGTGG 
TCAAAACAAG TTGTTCCTTT TGTTTATCAA ACTATTGTCA AGGACATCCG AGCTTTCGAC 
TCCCGTTTCT CCAATATCAA AACATTGGAT GATTTGTTTC CTCTGAGAAG TATGGTCTTT 
ATGCTGGGAA CTCCCTATTA TGGCTGCACT GGAGAAGTTC AGGATTCAGG TGATGTGATT 
ACAGAAGGTA GGATTCGTGT GATTTTCAGC ATTCCATGTG AACCCAATCT TGATGCTTTA 
ATACAGAACC AGCATGAGAA AGAGAGAGGA GCAGAAAAAT TCTGCCTACA GATCCTTTCA 
AAAAAAAGGG GAAATGGATC TAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006713736.1
CDS	119..2905
Translation	MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKIFTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKAIEKGETLPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHKIMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCAPEETTFHLLHLSLMREYIDYEFSVLKEKITFKYDIERIIDDWILMGFLVGNDFIPHLPHLHINHDALPLLYGTYVTILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKWFESKVGNKYLNEAAGVAAEEARNYKEKKKLKGQENSLCWTALDKNEGEMITSKDNLEDETEDDDLFETEFRQYKRTYYMTKMGVDVVSDDFLADQAACYVQAIQWILHYYYHGVQSWSWYYPYHYAPFLSDIHNISTLKIHFELGKPFKPFEQLLAVLPAASKNLLPACYQHLMTNEDSPIIEYYPPDFKTDLNGKQQEWEAVVLIPFIDEKRLLEAMETCNHSLKKEERKRNQHSECLMCWYDRDTEFIYPSPWPEKFPAIERCCTRYKIISLDAWRVDINKNKITRIDQKALYFCGFPTLKHIRHKFFLKKSGVQVFQQSSRGENMMLEILVDAESDELTVENVASSVLGKSVFVNWPHLEEARVVAVSDGETKFYLEEPPGTQKLYSGRTAPPSKVVHLGDKEQSNWAKEVQGISEHYLRRKGIIINETSAVVYAQLLTGRKYQINQNGEVRLEKQWSKQVVPFVYQTIVKDIRAFDSRFSNIKTLDDLFPLRSMVFMLGTPYYGCTGEVQDSGDVITEGRIRVIFSIPCEPNLDALIQNQHEKERGAEKFCLQILSKKRGNGSK

Target ORF information:

RefSeq Version	XM_006713673.2
Organism	Homo sapiens(human)
Definition	Homo sapiens 5'-3' exoribonuclease 1 (XRN1), transcript variant X8, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006713673.2

ORF Insert Sequence:

ATGGGAGTCC CCAAGTTTTA CAGATGGATC TCAGAGCGGT ATCCCTGTCT CAGCGAAGTG 
GTGAAAGAGC ATCAGATTCC TGAATTTGAC AACTTGTACC TGGATATGAA TGGAATTATA 
CATCAGTGCT CCCATCCTAA TGATGATGAT GTTCACTTTA GAATTTCAGA TGATAAAATC 
TTTACTGATA TTTTTCACTA CCTGGAGGTG TTGTTTCGCA TTATTAAACC CAGGAAAGTG 
TTCTTTATGG CTGTAGATGG TGTGGCTCCT CGAGCAAAAA TGAACCAGCA GCGTGGGAGG 
CGTTTTAGGT CAGCAAAGGA GGCAGAAGAC AAAATTAAAA AGGCAATAGA GAAGGGAGAA 
ACTCTTCCTA CAGAGGCCAG ATTTGATTCC AACTGTATCA CACCAGGAAC TGAATTTATG 
GCCAGGTTAC ATGAACATCT GAAGTATTTT GTAAATATGA AAATTTCCAC AGACAAGTCA 
TGGCAAGGAG TTACCATCTA CTTCTCAGGC CATGAGACTC CTGGAGAAGG AGAGCATAAA 
ATCATGGAAT TTATCAGATC CGAGAAAGCA AAGCCAGATC ATGATCCAAA CACCAGACAC 
TGTCTTTATG GTTTAGATGC TGACTTGATT ATGCTTGGAT TAACAAGTCA TGAGGCACAT 
TTTTCTCTCT TAAGAGAAGA AGTTCGATTT GGTGGCAAAA AAACACAACG GGTATGTGCT 
CCAGAAGAAA CTACATTTCA CCTTCTACAC TTGTCTTTAA TGAGAGAGTA TATTGACTAT 
GAGTTTTCAG TATTAAAAGA AAAGATCACA TTTAAATATG ATATTGAAAG GATAATAGAT 
GATTGGATTT TGATGGGGTT TCTTGTTGGT AATGATTTTA TCCCTCATCT ACCTCATTTA 
CATATTAATC ATGATGCACT GCCTCTTCTT TATGGAACAT ATGTTACCAT CCTGCCAGAA 
CTTGGGGGTT ATATTAATGA AAGTGGGCAC CTCAACTTAC CTCGATTTGA GAAATACCTT 
GTGAAACTAT CAGATTTTGA TCGGGAGCAC TTCAGTGAAG TTTTTGTGGA CCTAAAATGG 
TTTGAAAGCA AAGTTGGTAA CAAGTACCTC AATGAAGCAG CAGGTGTCGC AGCAGAAGAA 
GCCAGGAACT ACAAGGAAAA GAAAAAGTTA AAGGGCCAGG AAAATTCTCT GTGTTGGACT 
GCTTTAGACA AAAATGAAGG CGAAATGATA ACTTCTAAGG ATAATTTAGA AGATGAGACT 
GAAGATGATG ACCTATTTGA AACTGAGTTT AGACAATATA AAAGAACATA TTACATGACG 
AAGATGGGGG TTGACGTAGT ATCTGATGAC TTTCTGGCTG ATCAAGCTGC ATGTTATGTT 
CAGGCAATAC AGTGGATTTT GCACTATTAC TATCATGGAG TTCAGTCCTG GAGCTGGTAT 
TATCCTTATC ATTATGCACC TTTCCTGTCT GATATACACA ACATCAGTAC ACTCAAAATC 
CATTTTGAAC TAGGAAAACC TTTTAAGCCA TTTGAACAGC TTCTTGCTGT ACTTCCAGCA 
GCCAGCAAAA ATTTACTTCC TGCATGCTAC CAGCATTTGA TGACCAATGA AGACTCACCA 
ATTATAGAAT ATTACCCACC TGATTTTAAA ACTGACCTAA ATGGGAAACA ACAGGAATGG 
GAAGCTGTGG TGTTAATCCC TTTTATTGAT GAGAAGCGAT TATTGGAAGC CATGGAGACA 
TGTAACCACT CCCTCAAAAA GGAAGAGAGG AAAAGAAACC AACATAGTGA GTGCCTAATG 
TGCTGGTATG ATAGAGACAC AGAGTTTATC TATCCTTCTC CATGGCCAGA AAAGTTCCCT 
GCCATAGAAC GATGTTGTAC AAGGTATAAA ATAATATCCT TAGATGCTTG GCGTGTAGAC 
ATAAACAAAA ACAAAATAAC CAGAATTGAC CAGAAAGCAT TATATTTCTG TGGATTTCCT 
ACTCTGAAAC ACATCAGACA CAAATTTTTT TTGAAGAAAA GTGGTGTTCA AGTATTCCAG 
CAAAGCAGTC GTGGAGAAAA CATGATGTTG GAAATCTTAG TGGATGCAGA ATCAGATGAA 
CTTACCGTAG AAAATGTAGC TTCATCAGTG CTTGGAAAAT CTGTCTTTGT TAATTGGCCT 
CACCTTGAGG AAGCTAGAGT CGTGGCTGTA TCAGATGGAG AAACTAAGTT TTACTTGGAA 
GAACCTCCAG GAACACAGAA GCTTTATTCA GGAAGAACTG CCCCACCATC TAAAGTGGTT 
CATCTTGGAG ATAAAGAACA ATCTAACTGG GCAAAAGAAG TACAAGGAAT TTCAGAACAC 
TACCTGAGAA GAAAAGGAAT AATAATAAAT GAAACATCTG CAGTTGTGTA TGCTCAGTTA 
CTCACAGGTC GTAAATATCA AATAAATCAA AATGGTGAAG TTCGTCTAGA GAAACAGTGG 
TCAAAACAAG TTGTTCCTTT TGTTTATCAA ACTATTGTCA AGGACATCCG AGCTTTCGAC 
TCCCGTTTCT CCAATATCAA AACATTGGAT GATTTGTTTC CTCTGAGAAG TATGGTCTTT 
ATGCTGGGAA CTCCCTATTA TGGCTGCACT GGAGAAGTTC AGGATTCAGG TGATGTGATT 
ACAGAAGGTA GGATTCGTGT GATTTTCAGC ATTCCATGTG AACCCAATCT TGATGCTTTA 
ATACAGAACC AGCATGAGAA AGAGAGAGGA GCAGAAAAAT TCTGCCTACA GATCCTTTCA 
AAAAAAAGGG GAAATGGATC TAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

XRN1 ( XM_017006642.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016862131.1 Homo sapiens 5'-3' exoribonuclease 1 (XRN1), transcript variant X7, mRNA.

Price & Availability↑

CloneID	OHu94296
Clone ID Related Accession (Same CDS sequence)	XM_017006642.1
Accession Version	XM_017006642.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4071bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	5'-3' exoribonuclease 1 isoform X6
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGAGTCC CCAAGTTTTA CAGATGGATC TCAGAGCGGT ATCCCTGTCT CAGCGAAGTG 
GTGAAAGAGC ATCAGATTCC TGAATTTGAC AACTTGTACC TGGATATGAA TGGAATTATA 
CATCAGTGCT CCCATCCTAA TGATGATGAT GTTCACTTTA GAATTTCAGA TGATAAAATC 
TTTACTGATA TTTTTCACTA CCTGGAGGTG TTGTTTCGCA TTATTAAACC CAGGAAAGTG 
TTCTTTATGG CTGTAGATGG TGTGGCTCCT CGAGCAAAAA TGAACCAGCA GCGTGGGAGG 
CGTTTTAGGT CAGCAAAGGA GGCAGAAGAC AAAATTAAAA AGGCAATAGA GAAGGGAGAA 
ACTCTTCCTA CAGAGGCCAG ATTTGATTCC AACTGTATCA CACCAGGAAC TGAATTTATG 
GCCAGGTTAC ATGAACATCT GAAGTATTTT GTAAATATGA AAATTTCCAC AGACAAGTCA 
TGGCAAGGAG TTACCATCTA CTTCTCAGGC CATGAGACTC CTGGAGAAGG AGAGCATAAA 
ATCATGGAAT TTATCAGATC CGAGAAAGCA AAGCCAGATC ATGATCCAAA CACCAGACAC 
TGTCTTTATG GTTTAGATGC TGACTTGATT ATGCTTGGAT TAACAAGTCA TGAGGCACAT 
TTTTCTCTCT TAAGAGAAGA AGTTCGATTT GGTGGCAAAA AAACACAACG GGTATGTGCT 
CCAGAAGAAA CTACATTTCA CCTTCTACAC TTGTCTTTAA TGAGAGAGTA TATTGACTAT 
GAGTTTTCAG TATTAAAAGA AAAGATCACA TTTAAATATG ATATTGAAAG GATAATAGAT 
GATTGGATTT TGATGGGGTT TCTTGTTGGT AATGATTTTA TCCCTCATCT ACCTCATTTA 
CATATTAATC ATGATGCACT GCCTCTTCTT TATGGAACAT ATGTTACCAT CCTGCCAGAA 
CTTGGGGGTT ATATTAATGA AAGTGGGCAC CTCAACTTAC CTCGATTTGA GAAATACCTT 
GTGAAACTAT CAGATTTTGA TCGGGAGCAC TTCAGTGAAG TTTTTGTGGA CCTAAAATGG 
TTTGAAAGCA AAGTTGGTAA CAAGTACCTC AATGAAGCAG CAGGTGTCGC AGCAGAAGAA 
GCCAGGAACT ACAAGGAAAA GAAAAAGTTA AAGGGCCAGG AAAATTCTCT GTGTTGGACT 
GCTTTAGACA AAAATGAAGG CGAAATGATA ACTTCTAAGG ATAATTTAGA AGATGAGACT 
GAAGATGATG ACCTATTTGA AACTGAGTTT AGACAATATA AAAGAACATA TTACATGACG 
AAGATGGGGG TTGACGTAGT ATCTGATGAC TTTCTGGCTG ATCAAGCTGC ATGTTATGTT 
CAGGCAATAC AGTGGATTTT GCACTATTAC TATCATGGAG TTCAGTCCTG GAGCTGGTAT 
TATCCTTATC ATTATGCACC TTTCCTGTCT GATATACACA ACATCAGTAC ACTCAAAATC 
CATTTTGAAC TAGGAAAACC TTTTAAGCCA TTTGAACAGC TTCTTGCTGT ACTTCCAGCA 
GCCAGCAAAA ATTTACTTCC TGCATGCTAC CAGCATTTGA TGACCAATGA AGACTCACCA 
ATTATAGAAT ATTACCCACC TGATTTTAAA ACTGACCTAA ATGGGAAACA ACAGGAATGG 
GAAGCTGTGG TGTTAATCCC TTTTATTGAT GAGAAGCGAT TATTGGAAGC CATGGAGACA 
TGTAACCACT CCCTCAAAAA GGAAGAGAGG AAAAGAAACC AACATAGTGA GTGCCTAATG 
TGCTGGTATG ATAGAGACAC AGAGTTTATC TATCCTTCTC CATGGCCAGA AAAGTTCCCT 
GCCATAGAAC GATGTTGTAC AAGGTATAAA ATAATATCCT TAGATGCTTG GCGTGTAGAC 
ATAAACAAAA ACAAAATAAC CAGAATTGAC CAGAAAGCAT TATATTTCTG TGGATTTCCT 
ACTCTGAAAC ACATCAGACA CAAATTTTTT TTGAAGAAAA GTGGTGTTCA AGTATTCCAG 
CAAAGCAGTC GTGGAGAAAA CATGATGTTG GAAATCTTAG TGGATGCAGA ATCAGATGAA 
CTTACCGTAG AAAATGTAGC TTCATCAGTG CTTGGAAAAT CTGTCTTTGT TAATTGGCCT 
CACCTTGAGG AAGCTAGAGT CGTGGCTGTA TCAGATGGAG AAACTAAGTT TTACTTGGAA 
GAACCTCCAG GAACACAGAA GCTTTATTCA GGAAGAACTG CCCCACCATC TAAAGTGGTT 
CATCTTGGAG ATAAAGAACA ATCTAACTGG GCAAAAGAAG TACAAGGAAT TTCAGAACAC 
TACCTGAGAA GAAAAGGAAT AATAATAAAT GAAACATCTG CAGTTGTGTA TGCTCAGTTA 
CTCACAGGTC GTAAATATCA AATAAATCAA AATGGTGAAG TTCGTCTAGA GAAACAGTGG 
TCAAAACAAG TTGTTCCTTT TGTTTATCAA ACTATTGTCA AGGACATCCG AGCTTTCGAC 
TCCCGTTTCT CCAATATCAA AACATTGGAT GATTTGTTTC CTCTGAGAAG TATGGTCTTT 
ATGCTGGGAA CTCCCTATTA TGGCTGCACT GGAGAAGTTC AGGATTCAGG TGATGTGATT 
ACAGAAGGTA GGATTCGTGT GATTTTCAGC ATTCCATGTG AACCCAATCT TGATGCTTTA 
ATACAGAACC AGCATAAATA TTCTATAAAG TACAACCCAG GATATGTGTT GGCCAGTCGC 
CTTGGAGTGA GTGGATACCT TGTTTCAAGG TTTACAGGAA GTATTTTTAT TGGAAGAGGA 
TCTAGGAGAA ACCCTCATGG AGACCATAAA GCAAATGTGG GTTTAAATCT CAAATTCAAC 
AAGAAAAATG AGGAGGTACC TGGATATACT AAGAAAGTTG GAAGTGAATG GATGTATTCA 
TCTGCAGCAG AACAACTTCT GGCAGAGTAC TTAGAGAGAG CTCCAGAACT ATTTAGTTAT 
ATAGCCAAAA ATAGCCAAGA GGATGTGTTC TATGAAGATG ACATTTGGCC TGGAGAAAAT 
GAGAATGGTG CTGAAAAAGT TCAAGAAATT ATTACTTGGC TAAAAGGACA TCCTGTCAGT 
ACTTTATCTC GTTCTTCTTG TGATTTACAA ATTCTGGATG CAGCTATTGT TGAGAAAATT 
GAGGAAGAAG TCGAAAAGTG CAAGCAAAGA AAGAATAATA AGAAGGTGCG AGTAACAGTG 
AAACCCCATT TGCTATACAG ACCTTTAGAA CAGCAACATG GAGTCATTCC TGATCGGGAT 
GCAGAATTTT GTCTTTTTGA CCGTGTTGTA AATGTGAGAG AAAACTTCTC AGTTCCAGTT 
GGCCTTCGAG GCACCATCAT AGGAATAAAA GGAGCTAATA GAGAAGCCGA TGTACTATTT 
GAAGTATTAT TTGATGAAGA ATTTCCTGGA GGGTTAACAA TAAGATGCTC ACCTGGTAGA 
GGTTATCGAC TGCCAACAAG TGCCTTGGTG AACCTTTCTC ATGGGAGTCG CTCTGAAACT 
GGAAATCAGA AGTTGACAGC CATCGTAAAA CCACAACCAG CTGTACATCA ACATAGCTCA 
AGTTCATCAG TTTCCTCTGG GCATTTGGGA GCCCTCAACC ATTCCCCTCA ATCACTTTTT 
GTTCCTACTC AAGTACCTAC TAAAGATGAT GATGAATTCT GCAACATTTG GCAGTCCTTA 
CAGGGATCTG GAAAGATGCA ATACTTTCAG CCAACTATAC AAGAGAAGGG TGCAGTTCTA 
CCTCAAGAAA TAAGCCAAGT AAATCAACAT CATAAATCTG GCTTTAATGA CAACAGTGTT 
AAATATCAGC AAAGAAAACA TGACCCTCAC AGAAAATTTA AAGAAGAGTG TAAGAGTCCT 
AAAGCTGAGT GTTGGTCCCA AAAAATGTCC AATAAGCAGC CTAACTCTGG AATTGAGAAC 
TTTTTAGCAT CTTTGAATAT CTCCAAAGAA AATGAAGTAC AGTCATCTCA TCATGGGGAG 
CCTCCAAGTG AAGAGCATTT GTCACCACAG TCATTTGCCA TGAAGAGATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016862131.1
CDS	119..4189
Translation	MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKIFTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKAIEKGETLPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHKIMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCAPEETTFHLLHLSLMREYIDYEFSVLKEKITFKYDIERIIDDWILMGFLVGNDFIPHLPHLHINHDALPLLYGTYVTILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKWFESKVGNKYLNEAAGVAAEEARNYKEKKKLKGQENSLCWTALDKNEGEMITSKDNLEDETEDDDLFETEFRQYKRTYYMTKMGVDVVSDDFLADQAACYVQAIQWILHYYYHGVQSWSWYYPYHYAPFLSDIHNISTLKIHFELGKPFKPFEQLLAVLPAASKNLLPACYQHLMTNEDSPIIEYYPPDFKTDLNGKQQEWEAVVLIPFIDEKRLLEAMETCNHSLKKEERKRNQHSECLMCWYDRDTEFIYPSPWPEKFPAIERCCTRYKIISLDAWRVDINKNKITRIDQKALYFCGFPTLKHIRHKFFLKKSGVQVFQQSSRGENMMLEILVDAESDELTVENVASSVLGKSVFVNWPHLEEARVVAVSDGETKFYLEEPPGTQKLYSGRTAPPSKVVHLGDKEQSNWAKEVQGISEHYLRRKGIIINETSAVVYAQLLTGRKYQINQNGEVRLEKQWSKQVVPFVYQTIVKDIRAFDSRFSNIKTLDDLFPLRSMVFMLGTPYYGCTGEVQDSGDVITEGRIRVIFSIPCEPNLDALIQNQHKYSIKYNPGYVLASRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFNKKNEEVPGYTKKVGSEWMYSSAAEQLLAEYLERAPELFSYIAKNSQEDVFYEDDIWPGENENGAEKVQEIITWLKGHPVSTLSRSSCDLQILDAAIVEKIEEEVEKCKQRKNNKKVRVTVKPHLLYRPLEQQHGVIPDRDAEFCLFDRVVNVRENFSVPVGLRGTIIGIKGANREADVLFEVLFDEEFPGGLTIRCSPGRGYRLPTSALVNLSHGSRSETGNQKLTAIVKPQPAVHQHSSSSSVSSGHLGALNHSPQSLFVPTQVPTKDDDEFCNIWQSLQGSGKMQYFQPTIQEKGAVLPQEISQVNQHHKSGFNDNSVKYQQRKHDPHRKFKEECKSPKAECWSQKMSNKQPNSGIENFLASLNISKENEVQSSHHGEPPSEEHLSPQSFAMKR

Target ORF information:

RefSeq Version	XM_017006642.1
Organism	Homo sapiens(human)
Definition	Homo sapiens 5'-3' exoribonuclease 1 (XRN1), transcript variant X7, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017006642.1

ORF Insert Sequence:

ATGGGAGTCC CCAAGTTTTA CAGATGGATC TCAGAGCGGT ATCCCTGTCT CAGCGAAGTG 
GTGAAAGAGC ATCAGATTCC TGAATTTGAC AACTTGTACC TGGATATGAA TGGAATTATA 
CATCAGTGCT CCCATCCTAA TGATGATGAT GTTCACTTTA GAATTTCAGA TGATAAAATC 
TTTACTGATA TTTTTCACTA CCTGGAGGTG TTGTTTCGCA TTATTAAACC CAGGAAAGTG 
TTCTTTATGG CTGTAGATGG TGTGGCTCCT CGAGCAAAAA TGAACCAGCA GCGTGGGAGG 
CGTTTTAGGT CAGCAAAGGA GGCAGAAGAC AAAATTAAAA AGGCAATAGA GAAGGGAGAA 
ACTCTTCCTA CAGAGGCCAG ATTTGATTCC AACTGTATCA CACCAGGAAC TGAATTTATG 
GCCAGGTTAC ATGAACATCT GAAGTATTTT GTAAATATGA AAATTTCCAC AGACAAGTCA 
TGGCAAGGAG TTACCATCTA CTTCTCAGGC CATGAGACTC CTGGAGAAGG AGAGCATAAA 
ATCATGGAAT TTATCAGATC CGAGAAAGCA AAGCCAGATC ATGATCCAAA CACCAGACAC 
TGTCTTTATG GTTTAGATGC TGACTTGATT ATGCTTGGAT TAACAAGTCA TGAGGCACAT 
TTTTCTCTCT TAAGAGAAGA AGTTCGATTT GGTGGCAAAA AAACACAACG GGTATGTGCT 
CCAGAAGAAA CTACATTTCA CCTTCTACAC TTGTCTTTAA TGAGAGAGTA TATTGACTAT 
GAGTTTTCAG TATTAAAAGA AAAGATCACA TTTAAATATG ATATTGAAAG GATAATAGAT 
GATTGGATTT TGATGGGGTT TCTTGTTGGT AATGATTTTA TCCCTCATCT ACCTCATTTA 
CATATTAATC ATGATGCACT GCCTCTTCTT TATGGAACAT ATGTTACCAT CCTGCCAGAA 
CTTGGGGGTT ATATTAATGA AAGTGGGCAC CTCAACTTAC CTCGATTTGA GAAATACCTT 
GTGAAACTAT CAGATTTTGA TCGGGAGCAC TTCAGTGAAG TTTTTGTGGA CCTAAAATGG 
TTTGAAAGCA AAGTTGGTAA CAAGTACCTC AATGAAGCAG CAGGTGTCGC AGCAGAAGAA 
GCCAGGAACT ACAAGGAAAA GAAAAAGTTA AAGGGCCAGG AAAATTCTCT GTGTTGGACT 
GCTTTAGACA AAAATGAAGG CGAAATGATA ACTTCTAAGG ATAATTTAGA AGATGAGACT 
GAAGATGATG ACCTATTTGA AACTGAGTTT AGACAATATA AAAGAACATA TTACATGACG 
AAGATGGGGG TTGACGTAGT ATCTGATGAC TTTCTGGCTG ATCAAGCTGC ATGTTATGTT 
CAGGCAATAC AGTGGATTTT GCACTATTAC TATCATGGAG TTCAGTCCTG GAGCTGGTAT 
TATCCTTATC ATTATGCACC TTTCCTGTCT GATATACACA ACATCAGTAC ACTCAAAATC 
CATTTTGAAC TAGGAAAACC TTTTAAGCCA TTTGAACAGC TTCTTGCTGT ACTTCCAGCA 
GCCAGCAAAA ATTTACTTCC TGCATGCTAC CAGCATTTGA TGACCAATGA AGACTCACCA 
ATTATAGAAT ATTACCCACC TGATTTTAAA ACTGACCTAA ATGGGAAACA ACAGGAATGG 
GAAGCTGTGG TGTTAATCCC TTTTATTGAT GAGAAGCGAT TATTGGAAGC CATGGAGACA 
TGTAACCACT CCCTCAAAAA GGAAGAGAGG AAAAGAAACC AACATAGTGA GTGCCTAATG 
TGCTGGTATG ATAGAGACAC AGAGTTTATC TATCCTTCTC CATGGCCAGA AAAGTTCCCT 
GCCATAGAAC GATGTTGTAC AAGGTATAAA ATAATATCCT TAGATGCTTG GCGTGTAGAC 
ATAAACAAAA ACAAAATAAC CAGAATTGAC CAGAAAGCAT TATATTTCTG TGGATTTCCT 
ACTCTGAAAC ACATCAGACA CAAATTTTTT TTGAAGAAAA GTGGTGTTCA AGTATTCCAG 
CAAAGCAGTC GTGGAGAAAA CATGATGTTG GAAATCTTAG TGGATGCAGA ATCAGATGAA 
CTTACCGTAG AAAATGTAGC TTCATCAGTG CTTGGAAAAT CTGTCTTTGT TAATTGGCCT 
CACCTTGAGG AAGCTAGAGT CGTGGCTGTA TCAGATGGAG AAACTAAGTT TTACTTGGAA 
GAACCTCCAG GAACACAGAA GCTTTATTCA GGAAGAACTG CCCCACCATC TAAAGTGGTT 
CATCTTGGAG ATAAAGAACA ATCTAACTGG GCAAAAGAAG TACAAGGAAT TTCAGAACAC 
TACCTGAGAA GAAAAGGAAT AATAATAAAT GAAACATCTG CAGTTGTGTA TGCTCAGTTA 
CTCACAGGTC GTAAATATCA AATAAATCAA AATGGTGAAG TTCGTCTAGA GAAACAGTGG 
TCAAAACAAG TTGTTCCTTT TGTTTATCAA ACTATTGTCA AGGACATCCG AGCTTTCGAC 
TCCCGTTTCT CCAATATCAA AACATTGGAT GATTTGTTTC CTCTGAGAAG TATGGTCTTT 
ATGCTGGGAA CTCCCTATTA TGGCTGCACT GGAGAAGTTC AGGATTCAGG TGATGTGATT 
ACAGAAGGTA GGATTCGTGT GATTTTCAGC ATTCCATGTG AACCCAATCT TGATGCTTTA 
ATACAGAACC AGCATAAATA TTCTATAAAG TACAACCCAG GATATGTGTT GGCCAGTCGC 
CTTGGAGTGA GTGGATACCT TGTTTCAAGG TTTACAGGAA GTATTTTTAT TGGAAGAGGA 
TCTAGGAGAA ACCCTCATGG AGACCATAAA GCAAATGTGG GTTTAAATCT CAAATTCAAC 
AAGAAAAATG AGGAGGTACC TGGATATACT AAGAAAGTTG GAAGTGAATG GATGTATTCA 
TCTGCAGCAG AACAACTTCT GGCAGAGTAC TTAGAGAGAG CTCCAGAACT ATTTAGTTAT 
ATAGCCAAAA ATAGCCAAGA GGATGTGTTC TATGAAGATG ACATTTGGCC TGGAGAAAAT 
GAGAATGGTG CTGAAAAAGT TCAAGAAATT ATTACTTGGC TAAAAGGACA TCCTGTCAGT 
ACTTTATCTC GTTCTTCTTG TGATTTACAA ATTCTGGATG CAGCTATTGT TGAGAAAATT 
GAGGAAGAAG TCGAAAAGTG CAAGCAAAGA AAGAATAATA AGAAGGTGCG AGTAACAGTG 
AAACCCCATT TGCTATACAG ACCTTTAGAA CAGCAACATG GAGTCATTCC TGATCGGGAT 
GCAGAATTTT GTCTTTTTGA CCGTGTTGTA AATGTGAGAG AAAACTTCTC AGTTCCAGTT 
GGCCTTCGAG GCACCATCAT AGGAATAAAA GGAGCTAATA GAGAAGCCGA TGTACTATTT 
GAAGTATTAT TTGATGAAGA ATTTCCTGGA GGGTTAACAA TAAGATGCTC ACCTGGTAGA 
GGTTATCGAC TGCCAACAAG TGCCTTGGTG AACCTTTCTC ATGGGAGTCG CTCTGAAACT 
GGAAATCAGA AGTTGACAGC CATCGTAAAA CCACAACCAG CTGTACATCA ACATAGCTCA 
AGTTCATCAG TTTCCTCTGG GCATTTGGGA GCCCTCAACC ATTCCCCTCA ATCACTTTTT 
GTTCCTACTC AAGTACCTAC TAAAGATGAT GATGAATTCT GCAACATTTG GCAGTCCTTA 
CAGGGATCTG GAAAGATGCA ATACTTTCAG CCAACTATAC AAGAGAAGGG TGCAGTTCTA 
CCTCAAGAAA TAAGCCAAGT AAATCAACAT CATAAATCTG GCTTTAATGA CAACAGTGTT 
AAATATCAGC AAAGAAAACA TGACCCTCAC AGAAAATTTA AAGAAGAGTG TAAGAGTCCT 
AAAGCTGAGT GTTGGTCCCA AAAAATGTCC AATAAGCAGC CTAACTCTGG AATTGAGAAC 
TTTTTAGCAT CTTTGAATAT CTCCAAAGAA AATGAAGTAC AGTCATCTCA TCATGGGGAG 
CCTCCAAGTG AAGAGCATTT GTCACCACAG TCATTTGCCA TGAAGAGATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

XRN1 ( XM_017006640.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016862129.1 Homo sapiens 5'-3' exoribonuclease 1 (XRN1), transcript variant X2, mRNA.

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CloneID	OHu94294
Clone ID Related Accession (Same CDS sequence)	XM_017006640.1
Accession Version	XM_017006640.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 5082bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	5'-3' exoribonuclease 1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGAGTCC CCAAGTTTTA CAGATGGATC TCAGAGCGGT ATCCCTGTCT CAGCGAAGTG 
GTGAAAGAGC ATCAGATTCC TGAATTTGAC AACTTGTACC TGGATATGAA TGGAATTATA 
CATCAGTGCT CCCATCCTAA TGATGATGAT GTTCACTTTA GAATTTCAGA TGATAAAATC 
TTTACTGATA TTTTTCACTA CCTGGAGGTG TTGTTTCGCA TTATTAAACC CAGGAAAGTG 
TTCTTTATGG CTGTAGATGG TGTGGCTCCT CGAGCAAAAA TGAACCAGCA GCGTGGGAGG 
CGTTTTAGGT CAGCAAAGGA GGCAGAAGAC AAAATTAAAA AGGCAATAGA GAAGGGAGAA 
ACTCTTCCTA CAGAGGCCAG ATTTGATTCC AACTGTATCA CACCAGGAAC TGAATTTATG 
GCCAGGTTAC ATGAACATCT GAAGTATTTT GTAAATATGA AAATTTCCAC AGACAAGTCA 
TGGCAAGGAG TTACCATCTA CTTCTCAGGC CATGAGACTC CTGGAGAAGG AGAGCATAAA 
ATCATGGAAT TTATCAGATC CGAGAAAGCA AAGCCAGATC ATGATCCAAA CACCAGACAC 
TGTCTTTATG GTTTAGATGC TGACTTGATT ATGCTTGGAT TAACAAGTCA TGAGGCACAT 
TTTTCTCTCT TAAGAGAAGA AGTTCGATTT GGTGGCAAAA AAACACAACG GGTATGTGCT 
CCAGAAGAAA CTACATTTCA CCTTCTACAC TTGTCTTTAA TGAGAGAGTA TATTGACTAT 
GAGTTTTCAG TATTAAAAGA AAAGATCACA TTTAAATATG ATATTGAAAG GATAATAGAT 
GATTGGATTT TGATGGGGTT TCTTGTTGGT AATGATTTTA TCCCTCATCT ACCTCATTTA 
CATATTAATC ATGATGCACT GCCTCTTCTT TATGGAACAT ATGTTACCAT CCTGCCAGAA 
CTTGGGGGTT ATATTAATGA AAGTGGGCAC CTCAACTTAC CTCGATTTGA GAAATACCTT 
GTGAAACTAT CAGATTTTGA TCGGGAGCAC TTCAGTGAAG TTTTTGTGGA CCTAAAATGG 
TTTGAAAGCA AAGTTGGTAA CAAGTACCTC AATGAAGCAG CAGGTGTCGC AGCAGAAGAA 
GCCAGGAACT ACAAGGAAAA GAAAAAGTTA AAGGGCCAGG AAAATTCTCT GTGTTGGACT 
GCTTTAGACA AAAATGAAGG CGAAATGATA ACTTCTAAGG ATAATTTAGA AGATGAGACT 
GAAGATGATG ACCTATTTGA AACTGAGTTT AGACAATATA AAAGAACATA TTACATGACG 
AAGATGGGGG TTGACGTAGT ATCTGATGAC TTTCTGGCTG ATCAAGCTGC ATGTTATGTT 
CAGGCAATAC AGTGGATTTT GCACTATTAC TATCATGGAG TTCAGTCCTG GAGCTGGTAT 
TATCCTTATC ATTATGCACC TTTCCTGTCT GATATACACA ACATCAGTAC ACTCAAAATC 
CATTTTGAAC TAGGAAAACC TTTTAAGCCA TTTGAACAGC TTCTTGCTGT ACTTCCAGCA 
GCCAGCAAAA ATTTACTTCC TGCATGCTAC CAGCATTTGA TGACCAATGA AGACTCACCA 
ATTATAGAAT ATTACCCACC TGATTTTAAA ACTGACCTAA ATGGGAAACA ACAGGAATGG 
GAAGCTGTGG TGTTAATCCC TTTTATTGAT GAGAAGCGAT TATTGGAAGC CATGGAGACA 
TGTAACCACT CCCTCAAAAA GGAAGAGAGG AAAAGAAACC AACATAGTGA GTGCCTAATG 
TGCTGGTATG ATAGAGACAC AGAGTTTATC TATCCTTCTC CATGGCCAGA AAAGTTCCCT 
GCCATAGAAC GATGTTGTAC AAGGTATAAA ATAATATCCT TAGATGCTTG GCGTGTAGAC 
ATAAACAAAA ACAAAATAAC CAGAATTGAC CAGAAAGCAT TATATTTCTG TGGATTTCCT 
ACTCTGAAAC ACATCAGACA CAAATTTTTT TTGAAGAAAA GTGGTGTTCA AGTATTCCAG 
CAAAGCAGTC GTGGAGAAAA CATGATGTTG GAAATCTTAG TGGATGCAGA ATCAGATGAA 
CTTACCGTAG AAAATGTAGC TTCATCAGTG CTTGGAAAAT CTGTCTTTGT TAATTGGCCT 
CACCTTGAGG AAGCTAGAGT CGTGGCTGTA TCAGATGGAG AAACTAAGTT TTACTTGGAA 
GAACCTCCAG GAACACAGAA GCTTTATTCA GGAAGAACTG CCCCACCATC TAAAGTGGTT 
CATCTTGGAG ATAAAGAACA ATCTAACTGG GCAAAAGAAG TACAAGGAAT TTCAGAACAC 
TACCTGAGAA GAAAAGGAAT AATAATAAAT GAAACATCTG CAGTTGTGTA TGCTCAGTTA 
CTCACAGGTC GTAAATATCA AATAAATCAA AATGGTGAAG TTCGTCTAGA GAAACAGTGG 
TCAAAACAAG TTGTTCCTTT TGTTTATCAA ACTATTGTCA AGGACATCCG AGCTTTCGAC 
TCCCGTTTCT CCAATATCAA AACATTGGAT GATTTGTTTC CTCTGAGAAG TATGGTCTTT 
ATGCTGGGAA CTCCCTATTA TGGCTGCACT GGAGAAGTTC AGGATTCAGG TGATGTGATT 
ACAGAAGGTA GGATTCGTGT GATTTTCAGC ATTCCATGTG AACCCAATCT TGATGCTTTA 
ATACAGAACC AGCATAAATA TTCTATAAAG TACAACCCAG GATATGTGTT GGCCAGTCGC 
CTTGGAGTGA GTGGATACCT TGTTTCAAGG TTTACAGGAA GTATTTTTAT TGGAAGAGGA 
TCTAGGAGAA ACCCTCATGG AGACCATAAA GCAAATGTGG GTTTAAATCT CAAATTCAAC 
AAGAAAAATG AGGAGGTACC TGGATATACT AAGAAAGTTG GAAGTGAATG GATGTATTCA 
TCTGCAGCAG AACAACTTCT GGCAGAGTAC TTAGAGAGAG CTCCAGAACT ATTTAGTTAT 
ATAGCCAAAA ATAGCCAAGA GGATGTGTTC TATGAAGATG ACATTTGGCC TGGAGAAAAT 
GAGAATGGTG CTGAAAAAGT TCAAGAAATT ATTACTTGGC TAAAAGGACA TCCTGTCAGT 
ACTTTATCTC GTTCTTCTTG TGATTTACAA ATTCTGGATG CAGCTATTGT TGAGAAAATT 
GAGGAAGAAG TCGAAAAGTG CAAGCAAAGA AAGAATAATA AGAAGGTGCG AGTAACAGTG 
AAACCCCATT TGCTATACAG ACCTTTAGAA CAGCAACATG GAGTCATTCC TGATCGGGAT 
GCAGAATTTT GTCTTTTTGA CCGTGTTGTA AATGTGAGAG AAAACTTCTC AGTTCCAGTT 
GGCCTTCGAG GCACCATCAT AGGAATAAAA GGAGCTAATA GAGAAGCCGA TGTACTATTT 
GAAGTATTAT TTGATGAAGA ATTTCCTGGA GGGTTAACAA TAAGATGCTC ACCTGGTAGA 
GGTTATCGAC TGCCAACAAG TGCCTTGGTG AACCTTTCTC ATGGGAGTCG CTCTGAAACT 
GGAAATCAGA AGTTGACAGC CATCGTAAAA CCACAACCAG CTGTACATCA ACATAGCTCA 
AGTTCATCAG TTTCCTCTGG GCATTTGGGA GCCCTCAACC ATTCCCCTCA ATCACTTTTT 
GTTCCTACTC AAGTACCTAC TAAAGATGAT GATGAATTCT GCAACATTTG GCAGTCCTTA 
CAGGGATCTG GAAAGATGCA ATACTTTCAG CCAACTATAC AAGAGAAGGG TGCAGTTCTA 
CCTCAAGAAA TAAGCCAAGT AAATCAACAT CATAAATCTG GCTTTAATGA CAACAGTGTT 
AAATATCAGC AAAGAAAACA TGACCCTCAC AGAAAATTTA AAGAAGAGTG TAAGAGTCCT 
AAAGCTGAGT GTTGGTCCCA AAAAATGTCC AATAAGCAGC CTAACTCTGG AATTGAGAAC 
TTTTTAGCAT CTTTGAATAT CTCCAAAGAA AATGAAGTAC AGTCATCTCA TCATGGGGAG 
CCTCCAAGTG AAGAGCATTT GTCACCACAG TCATTTGCCA TGGGAACACG GATGCTTAAA 
GAAATTCTAA AAATTGATGG CTCTAACACT GTGGACCATA AGAATGAAAT CAAACAGATT 
GCTAATGAAA TCCCTGTTTC CTCTAACAGA AGAGATGAAT ATGGATTACC CTCTCAGCCT 
AAACAAAATA AGAAATTAGC ATCTTATATG AACAAGCCTC ACAGTGCTAA TGAGTACCAT 
AATGTTCAGT CTATGGACAA TATGTGTTGG CCTGCCCCCA GCCAGATCCC TCCTGTATCC 
ACACCAGTAA CTGAACTTTC TCGAATTTGT TCCCTTGTTG GAATGCCACA ACCTGATTTC 
TCCTTTCTTA GGATGCCACA GACAATGACC GTTTGCCAAG TAAAATTATC TAATGGCTTA 
CTGGTACATG GGCCACAGTG CCACTCTGAA AATGAAGCCA AAGAGAAAGC TGCACTTTTT 
GCTTTACAAC AGTTGGGCTC CTTAGGCATG AATTTCCCTT TGCCTTCACA AGTATTTGCA 
AATTATCCTT CAGCTGTACC ACCTGGAACC ATTCCTCCAG CCTTTCCCCC ACCTACTGCT 
AATATAATGC CTTCGTCGTC TCATCTCTTT GGCTCAATGC CATGGGGACC ATCGGTGCCA 
GTTCCTGGGA AGCCCTTCCA TCATACTTTA TATTCTGGGA CCATGCCCAT GGCTGGGGGA 
ATACCAGGGG GTGTGCACAA TCAGTTTATA CCTCTGCAGG TTACTAAAAA AAGGGTTGCA 
AACAAAAAGA ACTTTGAGAA TAAGGAAGCC CAGAGTTCTC AAGCCACTCC AGTTCAGACT 
AGCCAGCCAG ATTCTTCCAA CATTGTCAAA GTAAGTCCAC GGGAGAGCTC ATCAGCTTCT 
TTGAAGTCCT CTCCGATTGC TCAACCTGCA TCTTCTTTTC AAGTTGAAAC TGCCTCTCAA 
GGCCATAGTA TATCTCACCA TAAGTCAACA CCAATCTCTT CTTCAAGAAG AAAATCAAGA 
AAACTGGCTG TTAATTTTGG TGTTTCTAAA CCTTCTGAGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016862129.1
CDS	119..5200
Translation	MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKIFTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKAIEKGETLPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHKIMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCAPEETTFHLLHLSLMREYIDYEFSVLKEKITFKYDIERIIDDWILMGFLVGNDFIPHLPHLHINHDALPLLYGTYVTILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKWFESKVGNKYLNEAAGVAAEEARNYKEKKKLKGQENSLCWTALDKNEGEMITSKDNLEDETEDDDLFETEFRQYKRTYYMTKMGVDVVSDDFLADQAACYVQAIQWILHYYYHGVQSWSWYYPYHYAPFLSDIHNISTLKIHFELGKPFKPFEQLLAVLPAASKNLLPACYQHLMTNEDSPIIEYYPPDFKTDLNGKQQEWEAVVLIPFIDEKRLLEAMETCNHSLKKEERKRNQHSECLMCWYDRDTEFIYPSPWPEKFPAIERCCTRYKIISLDAWRVDINKNKITRIDQKALYFCGFPTLKHIRHKFFLKKSGVQVFQQSSRGENMMLEILVDAESDELTVENVASSVLGKSVFVNWPHLEEARVVAVSDGETKFYLEEPPGTQKLYSGRTAPPSKVVHLGDKEQSNWAKEVQGISEHYLRRKGIIINETSAVVYAQLLTGRKYQINQNGEVRLEKQWSKQVVPFVYQTIVKDIRAFDSRFSNIKTLDDLFPLRSMVFMLGTPYYGCTGEVQDSGDVITEGRIRVIFSIPCEPNLDALIQNQHKYSIKYNPGYVLASRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFNKKNEEVPGYTKKVGSEWMYSSAAEQLLAEYLERAPELFSYIAKNSQEDVFYEDDIWPGENENGAEKVQEIITWLKGHPVSTLSRSSCDLQILDAAIVEKIEEEVEKCKQRKNNKKVRVTVKPHLLYRPLEQQHGVIPDRDAEFCLFDRVVNVRENFSVPVGLRGTIIGIKGANREADVLFEVLFDEEFPGGLTIRCSPGRGYRLPTSALVNLSHGSRSETGNQKLTAIVKPQPAVHQHSSSSSVSSGHLGALNHSPQSLFVPTQVPTKDDDEFCNIWQSLQGSGKMQYFQPTIQEKGAVLPQEISQVNQHHKSGFNDNSVKYQQRKHDPHRKFKEECKSPKAECWSQKMSNKQPNSGIENFLASLNISKENEVQSSHHGEPPSEEHLSPQSFAMGTRMLKEILKIDGSNTVDHKNEIKQIANEIPVSSNRRDEYGLPSQPKQNKKLASYMNKPHSANEYHNVQSMDNMCWPAPSQIPPVSTPVTELSRICSLVGMPQPDFSFLRMPQTMTVCQVKLSNGLLVHGPQCHSENEAKEKAALFALQQLGSLGMNFPLPSQVFANYPSAVPPGTIPPAFPPPTANIMPSSSHLFGSMPWGPSVPVPGKPFHHTLYSGTMPMAGGIPGGVHNQFIPLQVTKKRVANKKNFENKEAQSSQATPVQTSQPDSSNIVKVSPRESSSASLKSSPIAQPASSFQVETASQGHSISHHKSTPISSSRRKSRKLAVNFGVSKPSE

Target ORF information:

RefSeq Version	XM_017006640.1
Organism	Homo sapiens(human)
Definition	Homo sapiens 5'-3' exoribonuclease 1 (XRN1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017006640.1

ORF Insert Sequence:

ATGGGAGTCC CCAAGTTTTA CAGATGGATC TCAGAGCGGT ATCCCTGTCT CAGCGAAGTG 
GTGAAAGAGC ATCAGATTCC TGAATTTGAC AACTTGTACC TGGATATGAA TGGAATTATA 
CATCAGTGCT CCCATCCTAA TGATGATGAT GTTCACTTTA GAATTTCAGA TGATAAAATC 
TTTACTGATA TTTTTCACTA CCTGGAGGTG TTGTTTCGCA TTATTAAACC CAGGAAAGTG 
TTCTTTATGG CTGTAGATGG TGTGGCTCCT CGAGCAAAAA TGAACCAGCA GCGTGGGAGG 
CGTTTTAGGT CAGCAAAGGA GGCAGAAGAC AAAATTAAAA AGGCAATAGA GAAGGGAGAA 
ACTCTTCCTA CAGAGGCCAG ATTTGATTCC AACTGTATCA CACCAGGAAC TGAATTTATG 
GCCAGGTTAC ATGAACATCT GAAGTATTTT GTAAATATGA AAATTTCCAC AGACAAGTCA 
TGGCAAGGAG TTACCATCTA CTTCTCAGGC CATGAGACTC CTGGAGAAGG AGAGCATAAA 
ATCATGGAAT TTATCAGATC CGAGAAAGCA AAGCCAGATC ATGATCCAAA CACCAGACAC 
TGTCTTTATG GTTTAGATGC TGACTTGATT ATGCTTGGAT TAACAAGTCA TGAGGCACAT 
TTTTCTCTCT TAAGAGAAGA AGTTCGATTT GGTGGCAAAA AAACACAACG GGTATGTGCT 
CCAGAAGAAA CTACATTTCA CCTTCTACAC TTGTCTTTAA TGAGAGAGTA TATTGACTAT 
GAGTTTTCAG TATTAAAAGA AAAGATCACA TTTAAATATG ATATTGAAAG GATAATAGAT 
GATTGGATTT TGATGGGGTT TCTTGTTGGT AATGATTTTA TCCCTCATCT ACCTCATTTA 
CATATTAATC ATGATGCACT GCCTCTTCTT TATGGAACAT ATGTTACCAT CCTGCCAGAA 
CTTGGGGGTT ATATTAATGA AAGTGGGCAC CTCAACTTAC CTCGATTTGA GAAATACCTT 
GTGAAACTAT CAGATTTTGA TCGGGAGCAC TTCAGTGAAG TTTTTGTGGA CCTAAAATGG 
TTTGAAAGCA AAGTTGGTAA CAAGTACCTC AATGAAGCAG CAGGTGTCGC AGCAGAAGAA 
GCCAGGAACT ACAAGGAAAA GAAAAAGTTA AAGGGCCAGG AAAATTCTCT GTGTTGGACT 
GCTTTAGACA AAAATGAAGG CGAAATGATA ACTTCTAAGG ATAATTTAGA AGATGAGACT 
GAAGATGATG ACCTATTTGA AACTGAGTTT AGACAATATA AAAGAACATA TTACATGACG 
AAGATGGGGG TTGACGTAGT ATCTGATGAC TTTCTGGCTG ATCAAGCTGC ATGTTATGTT 
CAGGCAATAC AGTGGATTTT GCACTATTAC TATCATGGAG TTCAGTCCTG GAGCTGGTAT 
TATCCTTATC ATTATGCACC TTTCCTGTCT GATATACACA ACATCAGTAC ACTCAAAATC 
CATTTTGAAC TAGGAAAACC TTTTAAGCCA TTTGAACAGC TTCTTGCTGT ACTTCCAGCA 
GCCAGCAAAA ATTTACTTCC TGCATGCTAC CAGCATTTGA TGACCAATGA AGACTCACCA 
ATTATAGAAT ATTACCCACC TGATTTTAAA ACTGACCTAA ATGGGAAACA ACAGGAATGG 
GAAGCTGTGG TGTTAATCCC TTTTATTGAT GAGAAGCGAT TATTGGAAGC CATGGAGACA 
TGTAACCACT CCCTCAAAAA GGAAGAGAGG AAAAGAAACC AACATAGTGA GTGCCTAATG 
TGCTGGTATG ATAGAGACAC AGAGTTTATC TATCCTTCTC CATGGCCAGA AAAGTTCCCT 
GCCATAGAAC GATGTTGTAC AAGGTATAAA ATAATATCCT TAGATGCTTG GCGTGTAGAC 
ATAAACAAAA ACAAAATAAC CAGAATTGAC CAGAAAGCAT TATATTTCTG TGGATTTCCT 
ACTCTGAAAC ACATCAGACA CAAATTTTTT TTGAAGAAAA GTGGTGTTCA AGTATTCCAG 
CAAAGCAGTC GTGGAGAAAA CATGATGTTG GAAATCTTAG TGGATGCAGA ATCAGATGAA 
CTTACCGTAG AAAATGTAGC TTCATCAGTG CTTGGAAAAT CTGTCTTTGT TAATTGGCCT 
CACCTTGAGG AAGCTAGAGT CGTGGCTGTA TCAGATGGAG AAACTAAGTT TTACTTGGAA 
GAACCTCCAG GAACACAGAA GCTTTATTCA GGAAGAACTG CCCCACCATC TAAAGTGGTT 
CATCTTGGAG ATAAAGAACA ATCTAACTGG GCAAAAGAAG TACAAGGAAT TTCAGAACAC 
TACCTGAGAA GAAAAGGAAT AATAATAAAT GAAACATCTG CAGTTGTGTA TGCTCAGTTA 
CTCACAGGTC GTAAATATCA AATAAATCAA AATGGTGAAG TTCGTCTAGA GAAACAGTGG 
TCAAAACAAG TTGTTCCTTT TGTTTATCAA ACTATTGTCA AGGACATCCG AGCTTTCGAC 
TCCCGTTTCT CCAATATCAA AACATTGGAT GATTTGTTTC CTCTGAGAAG TATGGTCTTT 
ATGCTGGGAA CTCCCTATTA TGGCTGCACT GGAGAAGTTC AGGATTCAGG TGATGTGATT 
ACAGAAGGTA GGATTCGTGT GATTTTCAGC ATTCCATGTG AACCCAATCT TGATGCTTTA 
ATACAGAACC AGCATAAATA TTCTATAAAG TACAACCCAG GATATGTGTT GGCCAGTCGC 
CTTGGAGTGA GTGGATACCT TGTTTCAAGG TTTACAGGAA GTATTTTTAT TGGAAGAGGA 
TCTAGGAGAA ACCCTCATGG AGACCATAAA GCAAATGTGG GTTTAAATCT CAAATTCAAC 
AAGAAAAATG AGGAGGTACC TGGATATACT AAGAAAGTTG GAAGTGAATG GATGTATTCA 
TCTGCAGCAG AACAACTTCT GGCAGAGTAC TTAGAGAGAG CTCCAGAACT ATTTAGTTAT 
ATAGCCAAAA ATAGCCAAGA GGATGTGTTC TATGAAGATG ACATTTGGCC TGGAGAAAAT 
GAGAATGGTG CTGAAAAAGT TCAAGAAATT ATTACTTGGC TAAAAGGACA TCCTGTCAGT 
ACTTTATCTC GTTCTTCTTG TGATTTACAA ATTCTGGATG CAGCTATTGT TGAGAAAATT 
GAGGAAGAAG TCGAAAAGTG CAAGCAAAGA AAGAATAATA AGAAGGTGCG AGTAACAGTG 
AAACCCCATT TGCTATACAG ACCTTTAGAA CAGCAACATG GAGTCATTCC TGATCGGGAT 
GCAGAATTTT GTCTTTTTGA CCGTGTTGTA AATGTGAGAG AAAACTTCTC AGTTCCAGTT 
GGCCTTCGAG GCACCATCAT AGGAATAAAA GGAGCTAATA GAGAAGCCGA TGTACTATTT 
GAAGTATTAT TTGATGAAGA ATTTCCTGGA GGGTTAACAA TAAGATGCTC ACCTGGTAGA 
GGTTATCGAC TGCCAACAAG TGCCTTGGTG AACCTTTCTC ATGGGAGTCG CTCTGAAACT 
GGAAATCAGA AGTTGACAGC CATCGTAAAA CCACAACCAG CTGTACATCA ACATAGCTCA 
AGTTCATCAG TTTCCTCTGG GCATTTGGGA GCCCTCAACC ATTCCCCTCA ATCACTTTTT 
GTTCCTACTC AAGTACCTAC TAAAGATGAT GATGAATTCT GCAACATTTG GCAGTCCTTA 
CAGGGATCTG GAAAGATGCA ATACTTTCAG CCAACTATAC AAGAGAAGGG TGCAGTTCTA 
CCTCAAGAAA TAAGCCAAGT AAATCAACAT CATAAATCTG GCTTTAATGA CAACAGTGTT 
AAATATCAGC AAAGAAAACA TGACCCTCAC AGAAAATTTA AAGAAGAGTG TAAGAGTCCT 
AAAGCTGAGT GTTGGTCCCA AAAAATGTCC AATAAGCAGC CTAACTCTGG AATTGAGAAC 
TTTTTAGCAT CTTTGAATAT CTCCAAAGAA AATGAAGTAC AGTCATCTCA TCATGGGGAG 
CCTCCAAGTG AAGAGCATTT GTCACCACAG TCATTTGCCA TGGGAACACG GATGCTTAAA 
GAAATTCTAA AAATTGATGG CTCTAACACT GTGGACCATA AGAATGAAAT CAAACAGATT 
GCTAATGAAA TCCCTGTTTC CTCTAACAGA AGAGATGAAT ATGGATTACC CTCTCAGCCT 
AAACAAAATA AGAAATTAGC ATCTTATATG AACAAGCCTC ACAGTGCTAA TGAGTACCAT 
AATGTTCAGT CTATGGACAA TATGTGTTGG CCTGCCCCCA GCCAGATCCC TCCTGTATCC 
ACACCAGTAA CTGAACTTTC TCGAATTTGT TCCCTTGTTG GAATGCCACA ACCTGATTTC 
TCCTTTCTTA GGATGCCACA GACAATGACC GTTTGCCAAG TAAAATTATC TAATGGCTTA 
CTGGTACATG GGCCACAGTG CCACTCTGAA AATGAAGCCA AAGAGAAAGC TGCACTTTTT 
GCTTTACAAC AGTTGGGCTC CTTAGGCATG AATTTCCCTT TGCCTTCACA AGTATTTGCA 
AATTATCCTT CAGCTGTACC ACCTGGAACC ATTCCTCCAG CCTTTCCCCC ACCTACTGCT 
AATATAATGC CTTCGTCGTC TCATCTCTTT GGCTCAATGC CATGGGGACC ATCGGTGCCA 
GTTCCTGGGA AGCCCTTCCA TCATACTTTA TATTCTGGGA CCATGCCCAT GGCTGGGGGA 
ATACCAGGGG GTGTGCACAA TCAGTTTATA CCTCTGCAGG TTACTAAAAA AAGGGTTGCA 
AACAAAAAGA ACTTTGAGAA TAAGGAAGCC CAGAGTTCTC AAGCCACTCC AGTTCAGACT 
AGCCAGCCAG ATTCTTCCAA CATTGTCAAA GTAAGTCCAC GGGAGAGCTC ATCAGCTTCT 
TTGAAGTCCT CTCCGATTGC TCAACCTGCA TCTTCTTTTC AAGTTGAAAC TGCCTCTCAA 
GGCCATAGTA TATCTCACCA TAAGTCAACA CCAATCTCTT CTTCAAGAAG AAAATCAAGA 
AAACTGGCTG TTAATTTTGG TGTTTCTAAA CCTTCTGAGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

XRN1 ( XM_017006641.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016862130.1 Homo sapiens 5'-3' exoribonuclease 1 (XRN1), transcript variant X4, mRNA.

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CloneID	OHu94295
Clone ID Related Accession (Same CDS sequence)	XM_017006641.1
Accession Version	XM_017006641.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4971bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	5'-3' exoribonuclease 1 isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGAGTCC CCAAGTTTTA CAGATGGATC TCAGAGCGGT ATCCCTGTCT CAGCGAAGTG 
GTGAAAGAGC ATCAGATTCC TGAATTTGAC AACTTGTACC TGGATATGAA TGGAATTATA 
CATCAGTGCT CCCATCCTAA TGATGATGAT GTTCACTTTA GAATTTCAGA TGATAAAATC 
TTTACTGATA TTTTTCACTA CCTGGAGGTG TTGTTTCGCA TTATTAAACC CAGGAAAGTG 
TTCTTTATGG CTGTAGATGG TGTGGCTCCT CGAGCAAAAA TGAACCAGCA GCGTGGGAGG 
CGTTTTAGGT CAGCAAAGGA GGCAGAAGAC AAAATTAAAA AGGCAATAGA GAAGGGAGAA 
ACTCTTCCTA CAGAGGCCAG ATTTGATTCC AACTGTATCA CACCAGGAAC TGAATTTATG 
GCCAGGTTAC ATGAACATCT GAAGTATTTT GTAAATATGA AAATTTCCAC AGACAAGTCA 
TGGCAAGGAG TTACCATCTA CTTCTCAGGC CATGAGACTC CTGGAGAAGG AGAGCATAAA 
ATCATGGAAT TTATCAGATC CGAGAAAGCA AAGCCAGATC ATGATCCAAA CACCAGACAC 
TGTCTTTATG GTTTAGATGC TGACTTGATT ATGCTTGGAT TAACAAGTCA TGAGGCACAT 
TTTTCTCTCT TAAGAGAAGA AGTTCGATTT GGTGGCAAAA AAACACAACG GGTATGTGCT 
CCAGAAGAAA CTACATTTCA CCTTCTACAC TTGTCTTTAA TGAGAGAGTA TATTGACTAT 
GAGTTTTCAG TATTAAAAGA AAAGATCACA TTTAAATATG ATATTGAAAG GATAATAGAT 
GATTGGATTT TGATGGGGTT TCTTGTTGGT AATGATTTTA TCCCTCATCT ACCTCATTTA 
CATATTAATC ATGATGCACT GCCTCTTCTT TATGGAACAT ATGTTACCAT CCTGCCAGAA 
CTTGGGGGTT ATATTAATGA AAGTGGGCAC CTCAACTTAC CTCGATTTGA GAAATACCTT 
GTGAAACTAT CAGATTTTGA TCGGGAGCAC TTCAGTGAAG TTTTTGTGGA CCTAAAATGG 
TTTGAAAGCA AAGTTGGTAA CAAGTACCTC AATGAAGCAG CAGGTGTCGC AGCAGAAGAA 
GCCAGGAACT ACAAGGAAAA GAAAAAGTTA AAGGGCCAGG AAAATTCTCT GTGTTGGACT 
GCTTTAGACA AAAATGAAGG CGAAATGATA ACTTCTAAGG ATAATTTAGA AGATGAGACT 
GAAGATGATG ACCTATTTGA AACTGAGTTT AGACAATATA AAAGAACATA TTACATGACG 
AAGATGGGGG TTGACGTAGT ATCTGATGAC TTTCTGGCTG ATCAAGCTGC ATGTTATGTT 
CAGGCAATAC AGTGGATTTT GCACTATTAC TATCATGGAG TTCAGTCCTG GAGCTGGTAT 
TATCCTTATC ATTATGCACC TTTCCTGTCT GATATACACA ACATCAGTAC ACTCAAAATC 
CATTTTGAAC TAGGAAAACC TTTTAAGCCA TTTGAACAGC TTCTTGCTGT ACTTCCAGCA 
GCCAGCAAAA ATTTACTTCC TGCATGCTAC CAGCATTTGA TGACCAATGA AGACTCACCA 
ATTATAGAAT ATTACCCACC TGATTTTAAA ACTGACCTAA ATGGGAAACA ACAGGAATGG 
GAAGCTGTGG TGTTAATCCC TTTTATTGAT GAGAAGCGAT TATTGGAAGC CATGGAGACA 
TGTAACCACT CCCTCAAAAA GGAAGAGAGG AAAAGAAACC AACATAGTGA GTGCCTAATG 
TGCTGGTATG ATAGAGACAC AGAGTTTATC TATCCTTCTC CATGGCCAGA AAAGTTCCCT 
GCCATAGAAC GATGTTGTAC AAGGTATAAA ATAATATCCT TAGATGCTTG GCGTGTAGAC 
ATAAACAAAA ACAAAATAAC CAGAATTGAC CAGAAAGCAT TATATTTCTG TGGATTTCCT 
ACTCTGAAAC ACATCAGACA CAAATTTTTT TTGAAGAAAA GTGGTGTTCA AGTATTCCAG 
CAAAGCAGTC GTGGAGAAAA CATGATGTTG GAAATCTTAG TGGATGCAGA ATCAGATGAA 
CTTACCGTAG AAAATGTAGC TTCATCAGTG CTTGGAAAAT CTGTCTTTGT TAATTGGCCT 
CACCTTGAGG AAGCTAGAGT CGTGGCTGTA TCAGATGGAG AAACTAAGTT TTACTTGGAA 
GAACCTCCAG GAACACAGAA GCTTTATTCA GGAAGAACTG CCCCACCATC TAAAGTGGTT 
CATCTTGGAG ATAAAGAACA ATCTAACTGG GCAAAAGAAG TACAAGGAAT TTCAGAACAC 
TACCTGAGAA GAAAAGGAAT AATAATAAAT GAAACATCTG CAGTTGTGTA TGCTCAGTTA 
CTCACAGGTC GTAAATATCA AATAAATCAA AATGGTGAAG TTCGTCTAGA GAAACAGTGG 
TCAAAACAAG TTGTTCCTTT TGTTTATCAA ACTATTGTCA AGGACATCCG AGCTTTCGAC 
TCCCGTTTCT CCAATATCAA AACATTGGAT GATTTGTTTC CTCTGAGAAG TATGGTCTTT 
ATGCTGGGAA CTCCCTATTA TGGCTGCACT GGAGAAGTTC AGGATTCAGG TGATGTGATT 
ACAGAAGGTA GGATTCGTGT GATTTTCAGC ATTCCATGTG AACCCAATCT TGATGCTTTA 
ATACAGAACC AGCATAAATA TTCTATAAAG TACAACCCAG GATATGTGTT GGCCAGTCGC 
CTTGGAGTGA GTGGATACCT TGTTTCAAGG TTTACAGGAA GTATTTTTAT TGGAAGAGGA 
TCTAGGAGAA ACCCTCATGG AGACCATAAA GCAAATGTGG GTTTAAATCT CAAATTCAAC 
AAGAAAAATG AGGAGGTACC TGGATATACT AAGAAAGTTG GAAGTGAATG GATGTATTCA 
TCTGCAGCAG AACAACTTCT GGCAGAGTAC TTAGAGAGAG CTCCAGAACT ATTTAGTTAT 
ATAGCCAAAA ATAGCCAAGA GGATGTGTTC TATGAAGATG ACATTTGGCC TGGAGAAAAT 
GAGAATGGTG CTGAAAAAGT TCAAGAAATT ATTACTTGGC TAAAAGGACA TCCTGTCAGT 
ACTTTATCTC GTTCTTCTTG TGATTTACAA ATTCTGGATG CAGCTATTGT TGAGAAAATT 
GAGGAAGAAG TCGAAAAGTG CAAGCAAAGA AAGAATAATA AGAAGGTGCG AGTAACAGTG 
AAACCCCATT TGCTATACAG ACCTTTAGAA CAGCAACATG GAGTCATTCC TGATCGGGAT 
GCAGAATTTT GTCTTTTTGA CCGTGTTGTA AATGTGAGAG AAAACTTCTC AGTTCCAGTT 
GGCCTTCGAG GCACCATCAT AGGAATAAAA GGAGCTAATA GAGAAGCCGA TGTACTATTT 
GAAGTATTAT TTGATGAAGA ATTTCCTGGA GGGTTAACAA TAAGATGCTC ACCTGGTAGA 
GGTTATCGAC TGCCAACAAG TGCCTTGGTG AACCTTTCTC ATGGGAGTCG CTCTGAAACT 
GGAAATCAGA AGTTGACAGC CATCGTAAAA CCACAACCAG CTGTACATCA ACATAGCTCA 
AGTTCATCAG TTTCCTCTGG GCATTTGGGA GCCCTCAACC ATTCCCCTCA ATCACTTTTT 
GTTCCTACTC AAGTACCTAC TAAAGATGAT GATGAATTCT GCAACATTTG GCAGTCCTTA 
CAGGGATCTG GAAAGATGCA ATACTTTCAG CCAACTATAC AAGAGAAGGG TGCAGTTCTA 
CCTCAAGAAA TAAGCCAAGT AAATCAACAT CATAAATCTG GCTTTAATGA CAACAGTGTT 
AAATATCAGC AAAGAAAACA TGACCCTCAC AGAAAATTTA AAGAAGAGTG TAAGAGTCCT 
AAAGCTGAGT GTTGGTCCCA AAAAATGTCC AATAAGCAGC CTAACTCTGG AATTGAGAAC 
TTTTTAGCAT CTTTGAATAT CTCCAAAGAA AATGAAGTAC AGTCATCTCA TCATGGGGAG 
CCTCCAAGTG AAGAGCATTT GTCACCACAG TCATTTGCCA TGAAGGGAAC ACGGATGCTT 
AAAGAAATTC TAAAAATTGA TGGCTCTAAC ACTGTGGACC ATAAGAATGA AATCAAACAG 
ATTGCTAATG AAATCCCTGT TTCCTCTAAC AGAAGAGATG AATATGGATT ACCCTCTCAG 
CCTAAACAAA ATAAGAAATT AGCATCTTAT ATGAACAAGC CTCACAGTGC TAATGAGTAC 
CATAATGTTC AGTCTATGGA CAATATGTGT TGGCCTGCCC CCAGCCAGAT CCCTCCTGTA 
TCCACACCAG TAACTGAACT TTCTCGAATT TGTTCCCTTG TTGGAATGCC ACAACCTGAT 
TTCTCCTTTC TTAGGATGCC ACAGGGCTCC TTAGGCATGA ATTTCCCTTT GCCTTCACAA 
GTATTTGCAA ATTATCCTTC AGCTGTACCA CCTGGAACCA TTCCTCCAGC CTTTCCCCCA 
CCTACTGCTA ATATAATGCC TTCGTCGTCT CATCTCTTTG GCTCAATGCC ATGGGGACCA 
TCGGTGCCAG TTCCTGGGAA GCCCTTCCAT CATACTTTAT ATTCTGGGAC CATGCCCATG 
GCTGGGGGAA TACCAGGGGG TGTGCACAAT CAGTTTATAC CTCTGCAGGT TACTAAAAAA 
AGGGTTGCAA ACAAAAAGAA CTTTGAGAAT AAGGAAGCCC AGAGTTCTCA AGCCACTCCA 
GTTCAGACTA GCCAGCCAGA TTCTTCCAAC ATTGTCAAAG TAAGTCCACG GGAGAGCTCA 
TCAGCTTCTT TGAAGTCCTC TCCGATTGCT CAACCTGCAT CTTCTTTTCA AGTTGAAACT 
GCCTCTCAAG GCCATAGTAT ATCTCACCAT AAGTCAACAC CAATCTCTTC TTCAAGAAGA 
AAATCAAGAA AACTGGCTGT TAATTTTGGT GTTTCTAAAC CTTCTGAGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016862130.1
CDS	119..5089
Translation	MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKIFTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKAIEKGETLPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHKIMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCAPEETTFHLLHLSLMREYIDYEFSVLKEKITFKYDIERIIDDWILMGFLVGNDFIPHLPHLHINHDALPLLYGTYVTILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKWFESKVGNKYLNEAAGVAAEEARNYKEKKKLKGQENSLCWTALDKNEGEMITSKDNLEDETEDDDLFETEFRQYKRTYYMTKMGVDVVSDDFLADQAACYVQAIQWILHYYYHGVQSWSWYYPYHYAPFLSDIHNISTLKIHFELGKPFKPFEQLLAVLPAASKNLLPACYQHLMTNEDSPIIEYYPPDFKTDLNGKQQEWEAVVLIPFIDEKRLLEAMETCNHSLKKEERKRNQHSECLMCWYDRDTEFIYPSPWPEKFPAIERCCTRYKIISLDAWRVDINKNKITRIDQKALYFCGFPTLKHIRHKFFLKKSGVQVFQQSSRGENMMLEILVDAESDELTVENVASSVLGKSVFVNWPHLEEARVVAVSDGETKFYLEEPPGTQKLYSGRTAPPSKVVHLGDKEQSNWAKEVQGISEHYLRRKGIIINETSAVVYAQLLTGRKYQINQNGEVRLEKQWSKQVVPFVYQTIVKDIRAFDSRFSNIKTLDDLFPLRSMVFMLGTPYYGCTGEVQDSGDVITEGRIRVIFSIPCEPNLDALIQNQHKYSIKYNPGYVLASRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFNKKNEEVPGYTKKVGSEWMYSSAAEQLLAEYLERAPELFSYIAKNSQEDVFYEDDIWPGENENGAEKVQEIITWLKGHPVSTLSRSSCDLQILDAAIVEKIEEEVEKCKQRKNNKKVRVTVKPHLLYRPLEQQHGVIPDRDAEFCLFDRVVNVRENFSVPVGLRGTIIGIKGANREADVLFEVLFDEEFPGGLTIRCSPGRGYRLPTSALVNLSHGSRSETGNQKLTAIVKPQPAVHQHSSSSSVSSGHLGALNHSPQSLFVPTQVPTKDDDEFCNIWQSLQGSGKMQYFQPTIQEKGAVLPQEISQVNQHHKSGFNDNSVKYQQRKHDPHRKFKEECKSPKAECWSQKMSNKQPNSGIENFLASLNISKENEVQSSHHGEPPSEEHLSPQSFAMKGTRMLKEILKIDGSNTVDHKNEIKQIANEIPVSSNRRDEYGLPSQPKQNKKLASYMNKPHSANEYHNVQSMDNMCWPAPSQIPPVSTPVTELSRICSLVGMPQPDFSFLRMPQGSLGMNFPLPSQVFANYPSAVPPGTIPPAFPPPTANIMPSSSHLFGSMPWGPSVPVPGKPFHHTLYSGTMPMAGGIPGGVHNQFIPLQVTKKRVANKKNFENKEAQSSQATPVQTSQPDSSNIVKVSPRESSSASLKSSPIAQPASSFQVETASQGHSISHHKSTPISSSRRKSRKLAVNFGVSKPSE

Target ORF information:

RefSeq Version	XM_017006641.1
Organism	Homo sapiens(human)
Definition	Homo sapiens 5'-3' exoribonuclease 1 (XRN1), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017006641.1

ORF Insert Sequence:

ATGGGAGTCC CCAAGTTTTA CAGATGGATC TCAGAGCGGT ATCCCTGTCT CAGCGAAGTG 
GTGAAAGAGC ATCAGATTCC TGAATTTGAC AACTTGTACC TGGATATGAA TGGAATTATA 
CATCAGTGCT CCCATCCTAA TGATGATGAT GTTCACTTTA GAATTTCAGA TGATAAAATC 
TTTACTGATA TTTTTCACTA CCTGGAGGTG TTGTTTCGCA TTATTAAACC CAGGAAAGTG 
TTCTTTATGG CTGTAGATGG TGTGGCTCCT CGAGCAAAAA TGAACCAGCA GCGTGGGAGG 
CGTTTTAGGT CAGCAAAGGA GGCAGAAGAC AAAATTAAAA AGGCAATAGA GAAGGGAGAA 
ACTCTTCCTA CAGAGGCCAG ATTTGATTCC AACTGTATCA CACCAGGAAC TGAATTTATG 
GCCAGGTTAC ATGAACATCT GAAGTATTTT GTAAATATGA AAATTTCCAC AGACAAGTCA 
TGGCAAGGAG TTACCATCTA CTTCTCAGGC CATGAGACTC CTGGAGAAGG AGAGCATAAA 
ATCATGGAAT TTATCAGATC CGAGAAAGCA AAGCCAGATC ATGATCCAAA CACCAGACAC 
TGTCTTTATG GTTTAGATGC TGACTTGATT ATGCTTGGAT TAACAAGTCA TGAGGCACAT 
TTTTCTCTCT TAAGAGAAGA AGTTCGATTT GGTGGCAAAA AAACACAACG GGTATGTGCT 
CCAGAAGAAA CTACATTTCA CCTTCTACAC TTGTCTTTAA TGAGAGAGTA TATTGACTAT 
GAGTTTTCAG TATTAAAAGA AAAGATCACA TTTAAATATG ATATTGAAAG GATAATAGAT 
GATTGGATTT TGATGGGGTT TCTTGTTGGT AATGATTTTA TCCCTCATCT ACCTCATTTA 
CATATTAATC ATGATGCACT GCCTCTTCTT TATGGAACAT ATGTTACCAT CCTGCCAGAA 
CTTGGGGGTT ATATTAATGA AAGTGGGCAC CTCAACTTAC CTCGATTTGA GAAATACCTT 
GTGAAACTAT CAGATTTTGA TCGGGAGCAC TTCAGTGAAG TTTTTGTGGA CCTAAAATGG 
TTTGAAAGCA AAGTTGGTAA CAAGTACCTC AATGAAGCAG CAGGTGTCGC AGCAGAAGAA 
GCCAGGAACT ACAAGGAAAA GAAAAAGTTA AAGGGCCAGG AAAATTCTCT GTGTTGGACT 
GCTTTAGACA AAAATGAAGG CGAAATGATA ACTTCTAAGG ATAATTTAGA AGATGAGACT 
GAAGATGATG ACCTATTTGA AACTGAGTTT AGACAATATA AAAGAACATA TTACATGACG 
AAGATGGGGG TTGACGTAGT ATCTGATGAC TTTCTGGCTG ATCAAGCTGC ATGTTATGTT 
CAGGCAATAC AGTGGATTTT GCACTATTAC TATCATGGAG TTCAGTCCTG GAGCTGGTAT 
TATCCTTATC ATTATGCACC TTTCCTGTCT GATATACACA ACATCAGTAC ACTCAAAATC 
CATTTTGAAC TAGGAAAACC TTTTAAGCCA TTTGAACAGC TTCTTGCTGT ACTTCCAGCA 
GCCAGCAAAA ATTTACTTCC TGCATGCTAC CAGCATTTGA TGACCAATGA AGACTCACCA 
ATTATAGAAT ATTACCCACC TGATTTTAAA ACTGACCTAA ATGGGAAACA ACAGGAATGG 
GAAGCTGTGG TGTTAATCCC TTTTATTGAT GAGAAGCGAT TATTGGAAGC CATGGAGACA 
TGTAACCACT CCCTCAAAAA GGAAGAGAGG AAAAGAAACC AACATAGTGA GTGCCTAATG 
TGCTGGTATG ATAGAGACAC AGAGTTTATC TATCCTTCTC CATGGCCAGA AAAGTTCCCT 
GCCATAGAAC GATGTTGTAC AAGGTATAAA ATAATATCCT TAGATGCTTG GCGTGTAGAC 
ATAAACAAAA ACAAAATAAC CAGAATTGAC CAGAAAGCAT TATATTTCTG TGGATTTCCT 
ACTCTGAAAC ACATCAGACA CAAATTTTTT TTGAAGAAAA GTGGTGTTCA AGTATTCCAG 
CAAAGCAGTC GTGGAGAAAA CATGATGTTG GAAATCTTAG TGGATGCAGA ATCAGATGAA 
CTTACCGTAG AAAATGTAGC TTCATCAGTG CTTGGAAAAT CTGTCTTTGT TAATTGGCCT 
CACCTTGAGG AAGCTAGAGT CGTGGCTGTA TCAGATGGAG AAACTAAGTT TTACTTGGAA 
GAACCTCCAG GAACACAGAA GCTTTATTCA GGAAGAACTG CCCCACCATC TAAAGTGGTT 
CATCTTGGAG ATAAAGAACA ATCTAACTGG GCAAAAGAAG TACAAGGAAT TTCAGAACAC 
TACCTGAGAA GAAAAGGAAT AATAATAAAT GAAACATCTG CAGTTGTGTA TGCTCAGTTA 
CTCACAGGTC GTAAATATCA AATAAATCAA AATGGTGAAG TTCGTCTAGA GAAACAGTGG 
TCAAAACAAG TTGTTCCTTT TGTTTATCAA ACTATTGTCA AGGACATCCG AGCTTTCGAC 
TCCCGTTTCT CCAATATCAA AACATTGGAT GATTTGTTTC CTCTGAGAAG TATGGTCTTT 
ATGCTGGGAA CTCCCTATTA TGGCTGCACT GGAGAAGTTC AGGATTCAGG TGATGTGATT 
ACAGAAGGTA GGATTCGTGT GATTTTCAGC ATTCCATGTG AACCCAATCT TGATGCTTTA 
ATACAGAACC AGCATAAATA TTCTATAAAG TACAACCCAG GATATGTGTT GGCCAGTCGC 
CTTGGAGTGA GTGGATACCT TGTTTCAAGG TTTACAGGAA GTATTTTTAT TGGAAGAGGA 
TCTAGGAGAA ACCCTCATGG AGACCATAAA GCAAATGTGG GTTTAAATCT CAAATTCAAC 
AAGAAAAATG AGGAGGTACC TGGATATACT AAGAAAGTTG GAAGTGAATG GATGTATTCA 
TCTGCAGCAG AACAACTTCT GGCAGAGTAC TTAGAGAGAG CTCCAGAACT ATTTAGTTAT 
ATAGCCAAAA ATAGCCAAGA GGATGTGTTC TATGAAGATG ACATTTGGCC TGGAGAAAAT 
GAGAATGGTG CTGAAAAAGT TCAAGAAATT ATTACTTGGC TAAAAGGACA TCCTGTCAGT 
ACTTTATCTC GTTCTTCTTG TGATTTACAA ATTCTGGATG CAGCTATTGT TGAGAAAATT 
GAGGAAGAAG TCGAAAAGTG CAAGCAAAGA AAGAATAATA AGAAGGTGCG AGTAACAGTG 
AAACCCCATT TGCTATACAG ACCTTTAGAA CAGCAACATG GAGTCATTCC TGATCGGGAT 
GCAGAATTTT GTCTTTTTGA CCGTGTTGTA AATGTGAGAG AAAACTTCTC AGTTCCAGTT 
GGCCTTCGAG GCACCATCAT AGGAATAAAA GGAGCTAATA GAGAAGCCGA TGTACTATTT 
GAAGTATTAT TTGATGAAGA ATTTCCTGGA GGGTTAACAA TAAGATGCTC ACCTGGTAGA 
GGTTATCGAC TGCCAACAAG TGCCTTGGTG AACCTTTCTC ATGGGAGTCG CTCTGAAACT 
GGAAATCAGA AGTTGACAGC CATCGTAAAA CCACAACCAG CTGTACATCA ACATAGCTCA 
AGTTCATCAG TTTCCTCTGG GCATTTGGGA GCCCTCAACC ATTCCCCTCA ATCACTTTTT 
GTTCCTACTC AAGTACCTAC TAAAGATGAT GATGAATTCT GCAACATTTG GCAGTCCTTA 
CAGGGATCTG GAAAGATGCA ATACTTTCAG CCAACTATAC AAGAGAAGGG TGCAGTTCTA 
CCTCAAGAAA TAAGCCAAGT AAATCAACAT CATAAATCTG GCTTTAATGA CAACAGTGTT 
AAATATCAGC AAAGAAAACA TGACCCTCAC AGAAAATTTA AAGAAGAGTG TAAGAGTCCT 
AAAGCTGAGT GTTGGTCCCA AAAAATGTCC AATAAGCAGC CTAACTCTGG AATTGAGAAC 
TTTTTAGCAT CTTTGAATAT CTCCAAAGAA AATGAAGTAC AGTCATCTCA TCATGGGGAG 
CCTCCAAGTG AAGAGCATTT GTCACCACAG TCATTTGCCA TGAAGGGAAC ACGGATGCTT 
AAAGAAATTC TAAAAATTGA TGGCTCTAAC ACTGTGGACC ATAAGAATGA AATCAAACAG 
ATTGCTAATG AAATCCCTGT TTCCTCTAAC AGAAGAGATG AATATGGATT ACCCTCTCAG 
CCTAAACAAA ATAAGAAATT AGCATCTTAT ATGAACAAGC CTCACAGTGC TAATGAGTAC 
CATAATGTTC AGTCTATGGA CAATATGTGT TGGCCTGCCC CCAGCCAGAT CCCTCCTGTA 
TCCACACCAG TAACTGAACT TTCTCGAATT TGTTCCCTTG TTGGAATGCC ACAACCTGAT 
TTCTCCTTTC TTAGGATGCC ACAGGGCTCC TTAGGCATGA ATTTCCCTTT GCCTTCACAA 
GTATTTGCAA ATTATCCTTC AGCTGTACCA CCTGGAACCA TTCCTCCAGC CTTTCCCCCA 
CCTACTGCTA ATATAATGCC TTCGTCGTCT CATCTCTTTG GCTCAATGCC ATGGGGACCA 
TCGGTGCCAG TTCCTGGGAA GCCCTTCCAT CATACTTTAT ATTCTGGGAC CATGCCCATG 
GCTGGGGGAA TACCAGGGGG TGTGCACAAT CAGTTTATAC CTCTGCAGGT TACTAAAAAA 
AGGGTTGCAA ACAAAAAGAA CTTTGAGAAT AAGGAAGCCC AGAGTTCTCA AGCCACTCCA 
GTTCAGACTA GCCAGCCAGA TTCTTCCAAC ATTGTCAAAG TAAGTCCACG GGAGAGCTCA 
TCAGCTTCTT TGAAGTCCTC TCCGATTGCT CAACCTGCAT CTTCTTTTCA AGTTGAAACT 
GCCTCTCAAG GCCATAGTAT ATCTCACCAT AAGTCAACAC CAATCTCTTC TTCAAGAAGA 
AAATCAAGAA AACTGGCTGT TAATTTTGGT GTTTCTAAAC CTTCTGAGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

XRN1 ( NM_001282857.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001269786.1 Homo sapiens 5'-3' exoribonuclease 1 (XRN1), transcript variant 3, mRNA.

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CloneID	OHu08281
Clone ID Related Accession (Same CDS sequence)	NM_001282857.2 , NM_001282857.1
Accession Version	NM_001282857.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 5085bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-15
Organism	Homo sapiens(human)
Product	5'-3' exoribonuclease 1 isoform c
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK096177.1, AC109992.6 and AC023508.16. On Jun 2, 2019 this sequence version replaced NM_001282857.1. Transcript Variant: This variant (3) lacks an in-frame exon in the 3' coding region, compared to variant 1. The encoded isoform (c) is shorter, compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: CR627396.1, CR749518.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGGAGTCC CCAAGTTTTA CAGATGGATC TCAGAGCGGT ATCCCTGTCT CAGCGAAGTG 
GTGAAAGAGC ATCAGATTCC TGAATTTGAC AACTTGTACC TGGATATGAA TGGAATTATA 
CATCAGTGCT CCCATCCTAA TGATGATGAT GTTCACTTTA GAATTTCAGA TGATAAAATC 
TTTACTGATA TTTTTCACTA CCTGGAGGTG TTGTTTCGCA TTATTAAACC CAGGAAAGTG 
TTCTTTATGG CTGTAGATGG TGTGGCTCCT CGAGCAAAAA TGAACCAGCA GCGTGGGAGG 
CGTTTTAGGT CAGCAAAGGA GGCAGAAGAC AAAATTAAAA AGGCAATAGA GAAGGGAGAA 
ACTCTTCCTA CAGAGGCCAG ATTTGATTCC AACTGTATCA CACCAGGAAC TGAATTTATG 
GCCAGGTTAC ATGAACATCT GAAGTATTTT GTAAATATGA AAATTTCCAC AGACAAGTCA 
TGGCAAGGAG TTACCATCTA CTTCTCAGGC CATGAGACTC CTGGAGAAGG AGAGCATAAA 
ATCATGGAAT TTATCAGATC CGAGAAAGCA AAGCCAGATC ATGATCCAAA CACCAGACAC 
TGTCTTTATG GTTTAGATGC TGACTTGATT ATGCTTGGAT TAACAAGTCA TGAGGCACAT 
TTTTCTCTCT TAAGAGAAGA AGTTCGATTT GGTGGCAAAA AAACACAACG GGTATGTGCT 
CCAGAAGAAA CTACATTTCA CCTTCTACAC TTGTCTTTAA TGAGAGAGTA TATTGACTAT 
GAGTTTTCAG TATTAAAAGA AAAGATCACA TTTAAATATG ATATTGAAAG GATAATAGAT 
GATTGGATTT TGATGGGGTT TCTTGTTGGT AATGATTTTA TCCCTCATCT ACCTCATTTA 
CATATTAATC ATGATGCACT GCCTCTTCTT TATGGAACAT ATGTTACCAT CCTGCCAGAA 
CTTGGGGGTT ATATTAATGA AAGTGGGCAC CTCAACTTAC CTCGATTTGA GAAATACCTT 
GTGAAACTAT CAGATTTTGA TCGGGAGCAC TTCAGTGAAG TTTTTGTGGA CCTAAAATGG 
TTTGAAAGCA AAGTTGGTAA CAAGTACCTC AATGAAGCAG CAGGTGTCGC AGCAGAAGAA 
GCCAGGAACT ACAAGGAAAA GAAAAAGTTA AAGGGCCAGG AAAATTCTCT GTGTTGGACT 
GCTTTAGACA AAAATGAAGG CGAAATGATA ACTTCTAAGG ATAATTTAGA AGATGAGACT 
GAAGATGATG ACCTATTTGA AACTGAGTTT AGACAATATA AAAGAACATA TTACATGACG 
AAGATGGGGG TTGACGTAGT ATCTGATGAC TTTCTGGCTG ATCAAGCTGC ATGTTATGTT 
CAGGCAATAC AGTGGATTTT GCACTATTAC TATCATGGAG TTCAGTCCTG GAGCTGGTAT 
TATCCTTATC ATTATGCACC TTTCCTGTCT GATATACACA ACATCAGTAC ACTCAAAATC 
CATTTTGAAC TAGGAAAACC TTTTAAGCCA TTTGAACAGC TTCTTGCTGT ACTTCCAGCA 
GCCAGCAAAA ATTTACTTCC TGCATGCTAC CAGCATTTGA TGACCAATGA AGACTCACCA 
ATTATAGAAT ATTACCCACC TGATTTTAAA ACTGACCTAA ATGGGAAACA ACAGGAATGG 
GAAGCTGTGG TGTTAATCCC TTTTATTGAT GAGAAGCGAT TATTGGAAGC CATGGAGACA 
TGTAACCACT CCCTCAAAAA GGAAGAGAGG AAAAGAAACC AACATAGTGA GTGCCTAATG 
TGCTGGTATG ATAGAGACAC AGAGTTTATC TATCCTTCTC CATGGCCAGA AAAGTTCCCT 
GCCATAGAAC GATGTTGTAC AAGGTATAAA ATAATATCCT TAGATGCTTG GCGTGTAGAC 
ATAAACAAAA ACAAAATAAC CAGAATTGAC CAGAAAGCAT TATATTTCTG TGGATTTCCT 
ACTCTGAAAC ACATCAGACA CAAATTTTTT TTGAAGAAAA GTGGTGTTCA AGTATTCCAG 
CAAAGCAGTC GTGGAGAAAA CATGATGTTG GAAATCTTAG TGGATGCAGA ATCAGATGAA 
CTTACCGTAG AAAATGTAGC TTCATCAGTG CTTGGAAAAT CTGTCTTTGT TAATTGGCCT 
CACCTTGAGG AAGCTAGAGT CGTGGCTGTA TCAGATGGAG AAACTAAGTT TTACTTGGAA 
GAACCTCCAG GAACACAGAA GCTTTATTCA GGAAGAACTG CCCCACCATC TAAAGTGGTT 
CATCTTGGAG ATAAAGAACA ATCTAACTGG GCAAAAGAAG TACAAGGAAT TTCAGAACAC 
TACCTGAGAA GAAAAGGAAT AATAATAAAT GAAACATCTG CAGTTGTGTA TGCTCAGTTA 
CTCACAGGTC GTAAATATCA AATAAATCAA AATGGTGAAG TTCGTCTAGA GAAACAGTGG 
TCAAAACAAG TTGTTCCTTT TGTTTATCAA ACTATTGTCA AGGACATCCG AGCTTTCGAC 
TCCCGTTTCT CCAATATCAA AACATTGGAT GATTTGTTTC CTCTGAGAAG TATGGTCTTT 
ATGCTGGGAA CTCCCTATTA TGGCTGCACT GGAGAAGTTC AGGATTCAGG TGATGTGATT 
ACAGAAGGTA GGATTCGTGT GATTTTCAGC ATTCCATGTG AACCCAATCT TGATGCTTTA 
ATACAGAACC AGCATAAATA TTCTATAAAG TACAACCCAG GATATGTGTT GGCCAGTCGC 
CTTGGAGTGA GTGGATACCT TGTTTCAAGG TTTACAGGAA GTATTTTTAT TGGAAGAGGA 
TCTAGGAGAA ACCCTCATGG AGACCATAAA GCAAATGTGG GTTTAAATCT CAAATTCAAC 
AAGAAAAATG AGGAGGTACC TGGATATACT AAGAAAGTTG GAAGTGAATG GATGTATTCA 
TCTGCAGCAG AACAACTTCT GGCAGAGTAC TTAGAGAGAG CTCCAGAACT ATTTAGTTAT 
ATAGCCAAAA ATAGCCAAGA GGATGTGTTC TATGAAGATG ACATTTGGCC TGGAGAAAAT 
GAGAATGGTG CTGAAAAAGT TCAAGAAATT ATTACTTGGC TAAAAGGACA TCCTGTCAGT 
ACTTTATCTC GTTCTTCTTG TGATTTACAA ATTCTGGATG CAGCTATTGT TGAGAAAATT 
GAGGAAGAAG TCGAAAAGTG CAAGCAAAGA AAGAATAATA AGAAGGTGCG AGTAACAGTG 
AAACCCCATT TGCTATACAG ACCTTTAGAA CAGCAACATG GAGTCATTCC TGATCGGGAT 
GCAGAATTTT GTCTTTTTGA CCGTGTTGTA AATGTGAGAG AAAACTTCTC AGTTCCAGTT 
GGCCTTCGAG GCACCATCAT AGGAATAAAA GGAGCTAATA GAGAAGCCGA TGTACTATTT 
GAAGTATTAT TTGATGAAGA ATTTCCTGGA GGGTTAACAA TAAGATGCTC ACCTGGTAGA 
GGTTATCGAC TGCCAACAAG TGCCTTGGTG AACCTTTCTC ATGGGAGTCG CTCTGAAACT 
GGAAATCAGA AGTTGACAGC CATCGTAAAA CCACAACCAG CTGTACATCA ACATAGCTCA 
AGTTCATCAG TTTCCTCTGG GCATTTGGGA GCCCTCAACC ATTCCCCTCA ATCACTTTTT 
GTTCCTACTC AAGTACCTAC TAAAGATGAT GATGAATTCT GCAACATTTG GCAGTCCTTA 
CAGGGATCTG GAAAGATGCA ATACTTTCAG CCAACTATAC AAGAGAAGGG TGCAGTTCTA 
CCTCAAGAAA TAAGCCAAGT AAATCAACAT CATAAATCTG GCTTTAATGA CAACAGTGTT 
AAATATCAGC AAAGAAAACA TGACCCTCAC AGAAAATTTA AAGAAGAGTG TAAGAGTCCT 
AAAGCTGAGT GTTGGTCCCA AAAAATGTCC AATAAGCAGC CTAACTCTGG AATTGAGAAC 
TTTTTAGCAT CTTTGAATAT CTCCAAAGAA AATGAAGTAC AGTCATCTCA TCATGGGGAG 
CCTCCAAGTG AAGAGCATTT GTCACCACAG TCATTTGCCA TGAAGGGAAC ACGGATGCTT 
AAAGAAATTC TAAAAATTGA TGGCTCTAAC ACTGTGGACC ATAAGAATGA AATCAAACAG 
ATTGCTAATG AAATCCCTGT TTCCTCTAAC AGAAGAGATG AATATGGATT ACCCTCTCAG 
CCTAAACAAA ATAAGAAATT AGCATCTTAT ATGAACAAGC CTCACAGTGC TAATGAGTAC 
CATAATGTTC AGTCTATGGA CAATATGTGT TGGCCTGCCC CCAGCCAGAT CCCTCCTGTA 
TCCACACCAG TAACTGAACT TTCTCGAATT TGTTCCCTTG TTGGAATGCC ACAACCTGAT 
TTCTCCTTTC TTAGGATGCC ACAGACAATG ACCGTTTGCC AAGTAAAATT ATCTAATGGC 
TTACTGGTAC ATGGGCCACA GTGCCACTCT GAAAATGAAG CCAAAGAGAA AGCTGCACTT 
TTTGCTTTAC AACAGTTGGG CTCCTTAGGC ATGAATTTCC CTTTGCCTTC ACAAGTATTT 
GCAAATTATC CTTCAGCTGT ACCACCTGGA ACCATTCCTC CAGCCTTTCC CCCACCTACT 
GCTAATATAA TGCCTTCGTC GTCTCATCTC TTTGGCTCAA TGCCATGGGG ACCATCGGTG 
CCAGTTCCTG GGAAGCCCTT CCATCATACT TTATATTCTG GGACCATGCC CATGGCTGGG 
GGAATACCAG GGGGTGTGCA CAATCAGTTT ATACCTCTGC AGGTTACTAA AAAAAGGGTT 
GCAAACAAAA AGAACTTTGA GAATAAGGAA GCCCAGAGTT CTCAAGCCAC TCCAGTTCAG 
ACTAGCCAGC CAGATTCTTC CAACATTGTC AAAGTAAGTC CACGGGAGAG CTCATCAGCT 
TCTTTGAAGT CCTCTCCGAT TGCTCAACCT GCATCTTCTT TTCAAGTTGA AACTGCCTCT 
CAAGGCCATA GTATATCTCA CCATAAGTCA ACACCAATCT CTTCTTCAAG AAGAAAATCA 
AGAAAACTGG CTGTTAATTT TGGTGTTTCT AAACCTTCTG AGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001269786.1
CDS	94..5178
Translation	MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKIFTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKAIEKGETLPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHKIMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCAPEETTFHLLHLSLMREYIDYEFSVLKEKITFKYDIERIIDDWILMGFLVGNDFIPHLPHLHINHDALPLLYGTYVTILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKWFESKVGNKYLNEAAGVAAEEARNYKEKKKLKGQENSLCWTALDKNEGEMITSKDNLEDETEDDDLFETEFRQYKRTYYMTKMGVDVVSDDFLADQAACYVQAIQWILHYYYHGVQSWSWYYPYHYAPFLSDIHNISTLKIHFELGKPFKPFEQLLAVLPAASKNLLPACYQHLMTNEDSPIIEYYPPDFKTDLNGKQQEWEAVVLIPFIDEKRLLEAMETCNHSLKKEERKRNQHSECLMCWYDRDTEFIYPSPWPEKFPAIERCCTRYKIISLDAWRVDINKNKITRIDQKALYFCGFPTLKHIRHKFFLKKSGVQVFQQSSRGENMMLEILVDAESDELTVENVASSVLGKSVFVNWPHLEEARVVAVSDGETKFYLEEPPGTQKLYSGRTAPPSKVVHLGDKEQSNWAKEVQGISEHYLRRKGIIINETSAVVYAQLLTGRKYQINQNGEVRLEKQWSKQVVPFVYQTIVKDIRAFDSRFSNIKTLDDLFPLRSMVFMLGTPYYGCTGEVQDSGDVITEGRIRVIFSIPCEPNLDALIQNQHKYSIKYNPGYVLASRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFNKKNEEVPGYTKKVGSEWMYSSAAEQLLAEYLERAPELFSYIAKNSQEDVFYEDDIWPGENENGAEKVQEIITWLKGHPVSTLSRSSCDLQILDAAIVEKIEEEVEKCKQRKNNKKVRVTVKPHLLYRPLEQQHGVIPDRDAEFCLFDRVVNVRENFSVPVGLRGTIIGIKGANREADVLFEVLFDEEFPGGLTIRCSPGRGYRLPTSALVNLSHGSRSETGNQKLTAIVKPQPAVHQHSSSSSVSSGHLGALNHSPQSLFVPTQVPTKDDDEFCNIWQSLQGSGKMQYFQPTIQEKGAVLPQEISQVNQHHKSGFNDNSVKYQQRKHDPHRKFKEECKSPKAECWSQKMSNKQPNSGIENFLASLNISKENEVQSSHHGEPPSEEHLSPQSFAMKGTRMLKEILKIDGSNTVDHKNEIKQIANEIPVSSNRRDEYGLPSQPKQNKKLASYMNKPHSANEYHNVQSMDNMCWPAPSQIPPVSTPVTELSRICSLVGMPQPDFSFLRMPQTMTVCQVKLSNGLLVHGPQCHSENEAKEKAALFALQQLGSLGMNFPLPSQVFANYPSAVPPGTIPPAFPPPTANIMPSSSHLFGSMPWGPSVPVPGKPFHHTLYSGTMPMAGGIPGGVHNQFIPLQVTKKRVANKKNFENKEAQSSQATPVQTSQPDSSNIVKVSPRESSSASLKSSPIAQPASSFQVETASQGHSISHHKSTPISSSRRKSRKLAVNFGVSKPSE

Target ORF information:

RefSeq Version	NM_001282857.2
Organism	Homo sapiens(human)
Definition	Homo sapiens 5'-3' exoribonuclease 1 (XRN1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001282857.2

ORF Insert Sequence:

ATGGGAGTCC CCAAGTTTTA CAGATGGATC TCAGAGCGGT ATCCCTGTCT CAGCGAAGTG 
GTGAAAGAGC ATCAGATTCC TGAATTTGAC AACTTGTACC TGGATATGAA TGGAATTATA 
CATCAGTGCT CCCATCCTAA TGATGATGAT GTTCACTTTA GAATTTCAGA TGATAAAATC 
TTTACTGATA TTTTTCACTA CCTGGAGGTG TTGTTTCGCA TTATTAAACC CAGGAAAGTG 
TTCTTTATGG CTGTAGATGG TGTGGCTCCT CGAGCAAAAA TGAACCAGCA GCGTGGGAGG 
CGTTTTAGGT CAGCAAAGGA GGCAGAAGAC AAAATTAAAA AGGCAATAGA GAAGGGAGAA 
ACTCTTCCTA CAGAGGCCAG ATTTGATTCC AACTGTATCA CACCAGGAAC TGAATTTATG 
GCCAGGTTAC ATGAACATCT GAAGTATTTT GTAAATATGA AAATTTCCAC AGACAAGTCA 
TGGCAAGGAG TTACCATCTA CTTCTCAGGC CATGAGACTC CTGGAGAAGG AGAGCATAAA 
ATCATGGAAT TTATCAGATC CGAGAAAGCA AAGCCAGATC ATGATCCAAA CACCAGACAC 
TGTCTTTATG GTTTAGATGC TGACTTGATT ATGCTTGGAT TAACAAGTCA TGAGGCACAT 
TTTTCTCTCT TAAGAGAAGA AGTTCGATTT GGTGGCAAAA AAACACAACG GGTATGTGCT 
CCAGAAGAAA CTACATTTCA CCTTCTACAC TTGTCTTTAA TGAGAGAGTA TATTGACTAT 
GAGTTTTCAG TATTAAAAGA AAAGATCACA TTTAAATATG ATATTGAAAG GATAATAGAT 
GATTGGATTT TGATGGGGTT TCTTGTTGGT AATGATTTTA TCCCTCATCT ACCTCATTTA 
CATATTAATC ATGATGCACT GCCTCTTCTT TATGGAACAT ATGTTACCAT CCTGCCAGAA 
CTTGGGGGTT ATATTAATGA AAGTGGGCAC CTCAACTTAC CTCGATTTGA GAAATACCTT 
GTGAAACTAT CAGATTTTGA TCGGGAGCAC TTCAGTGAAG TTTTTGTGGA CCTAAAATGG 
TTTGAAAGCA AAGTTGGTAA CAAGTACCTC AATGAAGCAG CAGGTGTCGC AGCAGAAGAA 
GCCAGGAACT ACAAGGAAAA GAAAAAGTTA AAGGGCCAGG AAAATTCTCT GTGTTGGACT 
GCTTTAGACA AAAATGAAGG CGAAATGATA ACTTCTAAGG ATAATTTAGA AGATGAGACT 
GAAGATGATG ACCTATTTGA AACTGAGTTT AGACAATATA AAAGAACATA TTACATGACG 
AAGATGGGGG TTGACGTAGT ATCTGATGAC TTTCTGGCTG ATCAAGCTGC ATGTTATGTT 
CAGGCAATAC AGTGGATTTT GCACTATTAC TATCATGGAG TTCAGTCCTG GAGCTGGTAT 
TATCCTTATC ATTATGCACC TTTCCTGTCT GATATACACA ACATCAGTAC ACTCAAAATC 
CATTTTGAAC TAGGAAAACC TTTTAAGCCA TTTGAACAGC TTCTTGCTGT ACTTCCAGCA 
GCCAGCAAAA ATTTACTTCC TGCATGCTAC CAGCATTTGA TGACCAATGA AGACTCACCA 
ATTATAGAAT ATTACCCACC TGATTTTAAA ACTGACCTAA ATGGGAAACA ACAGGAATGG 
GAAGCTGTGG TGTTAATCCC TTTTATTGAT GAGAAGCGAT TATTGGAAGC CATGGAGACA 
TGTAACCACT CCCTCAAAAA GGAAGAGAGG AAAAGAAACC AACATAGTGA GTGCCTAATG 
TGCTGGTATG ATAGAGACAC AGAGTTTATC TATCCTTCTC CATGGCCAGA AAAGTTCCCT 
GCCATAGAAC GATGTTGTAC AAGGTATAAA ATAATATCCT TAGATGCTTG GCGTGTAGAC 
ATAAACAAAA ACAAAATAAC CAGAATTGAC CAGAAAGCAT TATATTTCTG TGGATTTCCT 
ACTCTGAAAC ACATCAGACA CAAATTTTTT TTGAAGAAAA GTGGTGTTCA AGTATTCCAG 
CAAAGCAGTC GTGGAGAAAA CATGATGTTG GAAATCTTAG TGGATGCAGA ATCAGATGAA 
CTTACCGTAG AAAATGTAGC TTCATCAGTG CTTGGAAAAT CTGTCTTTGT TAATTGGCCT 
CACCTTGAGG AAGCTAGAGT CGTGGCTGTA TCAGATGGAG AAACTAAGTT TTACTTGGAA 
GAACCTCCAG GAACACAGAA GCTTTATTCA GGAAGAACTG CCCCACCATC TAAAGTGGTT 
CATCTTGGAG ATAAAGAACA ATCTAACTGG GCAAAAGAAG TACAAGGAAT TTCAGAACAC 
TACCTGAGAA GAAAAGGAAT AATAATAAAT GAAACATCTG CAGTTGTGTA TGCTCAGTTA 
CTCACAGGTC GTAAATATCA AATAAATCAA AATGGTGAAG TTCGTCTAGA GAAACAGTGG 
TCAAAACAAG TTGTTCCTTT TGTTTATCAA ACTATTGTCA AGGACATCCG AGCTTTCGAC 
TCCCGTTTCT CCAATATCAA AACATTGGAT GATTTGTTTC CTCTGAGAAG TATGGTCTTT 
ATGCTGGGAA CTCCCTATTA TGGCTGCACT GGAGAAGTTC AGGATTCAGG TGATGTGATT 
ACAGAAGGTA GGATTCGTGT GATTTTCAGC ATTCCATGTG AACCCAATCT TGATGCTTTA 
ATACAGAACC AGCATAAATA TTCTATAAAG TACAACCCAG GATATGTGTT GGCCAGTCGC 
CTTGGAGTGA GTGGATACCT TGTTTCAAGG TTTACAGGAA GTATTTTTAT TGGAAGAGGA 
TCTAGGAGAA ACCCTCATGG AGACCATAAA GCAAATGTGG GTTTAAATCT CAAATTCAAC 
AAGAAAAATG AGGAGGTACC TGGATATACT AAGAAAGTTG GAAGTGAATG GATGTATTCA 
TCTGCAGCAG AACAACTTCT GGCAGAGTAC TTAGAGAGAG CTCCAGAACT ATTTAGTTAT 
ATAGCCAAAA ATAGCCAAGA GGATGTGTTC TATGAAGATG ACATTTGGCC TGGAGAAAAT 
GAGAATGGTG CTGAAAAAGT TCAAGAAATT ATTACTTGGC TAAAAGGACA TCCTGTCAGT 
ACTTTATCTC GTTCTTCTTG TGATTTACAA ATTCTGGATG CAGCTATTGT TGAGAAAATT 
GAGGAAGAAG TCGAAAAGTG CAAGCAAAGA AAGAATAATA AGAAGGTGCG AGTAACAGTG 
AAACCCCATT TGCTATACAG ACCTTTAGAA CAGCAACATG GAGTCATTCC TGATCGGGAT 
GCAGAATTTT GTCTTTTTGA CCGTGTTGTA AATGTGAGAG AAAACTTCTC AGTTCCAGTT 
GGCCTTCGAG GCACCATCAT AGGAATAAAA GGAGCTAATA GAGAAGCCGA TGTACTATTT 
GAAGTATTAT TTGATGAAGA ATTTCCTGGA GGGTTAACAA TAAGATGCTC ACCTGGTAGA 
GGTTATCGAC TGCCAACAAG TGCCTTGGTG AACCTTTCTC ATGGGAGTCG CTCTGAAACT 
GGAAATCAGA AGTTGACAGC CATCGTAAAA CCACAACCAG CTGTACATCA ACATAGCTCA 
AGTTCATCAG TTTCCTCTGG GCATTTGGGA GCCCTCAACC ATTCCCCTCA ATCACTTTTT 
GTTCCTACTC AAGTACCTAC TAAAGATGAT GATGAATTCT GCAACATTTG GCAGTCCTTA 
CAGGGATCTG GAAAGATGCA ATACTTTCAG CCAACTATAC AAGAGAAGGG TGCAGTTCTA 
CCTCAAGAAA TAAGCCAAGT AAATCAACAT CATAAATCTG GCTTTAATGA CAACAGTGTT 
AAATATCAGC AAAGAAAACA TGACCCTCAC AGAAAATTTA AAGAAGAGTG TAAGAGTCCT 
AAAGCTGAGT GTTGGTCCCA AAAAATGTCC AATAAGCAGC CTAACTCTGG AATTGAGAAC 
TTTTTAGCAT CTTTGAATAT CTCCAAAGAA AATGAAGTAC AGTCATCTCA TCATGGGGAG 
CCTCCAAGTG AAGAGCATTT GTCACCACAG TCATTTGCCA TGAAGGGAAC ACGGATGCTT 
AAAGAAATTC TAAAAATTGA TGGCTCTAAC ACTGTGGACC ATAAGAATGA AATCAAACAG 
ATTGCTAATG AAATCCCTGT TTCCTCTAAC AGAAGAGATG AATATGGATT ACCCTCTCAG 
CCTAAACAAA ATAAGAAATT AGCATCTTAT ATGAACAAGC CTCACAGTGC TAATGAGTAC 
CATAATGTTC AGTCTATGGA CAATATGTGT TGGCCTGCCC CCAGCCAGAT CCCTCCTGTA 
TCCACACCAG TAACTGAACT TTCTCGAATT TGTTCCCTTG TTGGAATGCC ACAACCTGAT 
TTCTCCTTTC TTAGGATGCC ACAGACAATG ACCGTTTGCC AAGTAAAATT ATCTAATGGC 
TTACTGGTAC ATGGGCCACA GTGCCACTCT GAAAATGAAG CCAAAGAGAA AGCTGCACTT 
TTTGCTTTAC AACAGTTGGG CTCCTTAGGC ATGAATTTCC CTTTGCCTTC ACAAGTATTT 
GCAAATTATC CTTCAGCTGT ACCACCTGGA ACCATTCCTC CAGCCTTTCC CCCACCTACT 
GCTAATATAA TGCCTTCGTC GTCTCATCTC TTTGGCTCAA TGCCATGGGG ACCATCGGTG 
CCAGTTCCTG GGAAGCCCTT CCATCATACT TTATATTCTG GGACCATGCC CATGGCTGGG 
GGAATACCAG GGGGTGTGCA CAATCAGTTT ATACCTCTGC AGGTTACTAA AAAAAGGGTT 
GCAAACAAAA AGAACTTTGA GAATAAGGAA GCCCAGAGTT CTCAAGCCAC TCCAGTTCAG 
ACTAGCCAGC CAGATTCTTC CAACATTGTC AAAGTAAGTC CACGGGAGAG CTCATCAGCT 
TCTTTGAAGT CCTCTCCGAT TGCTCAACCT GCATCTTCTT TTCAAGTTGA AACTGCCTCT 
CAAGGCCATA GTATATCTCA CCATAAGTCA ACACCAATCT CTTCTTCAAG AAGAAAATCA 
AGAAAACTGG CTGTTAATTT TGGTGTTTCT AAACCTTCTG AGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

XRN1 ( NM_001282857.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001269786.1 Homo sapiens 5'-3' exoribonuclease 1 (XRN1), transcript variant 3, mRNA.

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CloneID	OHu08281
Clone ID Related Accession (Same CDS sequence)	NM_001282857.2 , NM_001282857.1
Accession Version	NM_001282857.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 5085bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Homo sapiens(human)
Product	5'-3' exoribonuclease 1 isoform c
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK096177.1, AC109992.6 and AC023508.16. On Sep 20, 2013 this sequence version replaced XM_005247542.1. Transcript Variant: This variant (3) lacks an in-frame exon in the 3' coding region, compared to variant 1. The encoded isoform (c) is shorter, compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: CR627396.1, CR749518.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGAGTCC CCAAGTTTTA CAGATGGATC TCAGAGCGGT ATCCCTGTCT CAGCGAAGTG 
GTGAAAGAGC ATCAGATTCC TGAATTTGAC AACTTGTACC TGGATATGAA TGGAATTATA 
CATCAGTGCT CCCATCCTAA TGATGATGAT GTTCACTTTA GAATTTCAGA TGATAAAATC 
TTTACTGATA TTTTTCACTA CCTGGAGGTG TTGTTTCGCA TTATTAAACC CAGGAAAGTG 
TTCTTTATGG CTGTAGATGG TGTGGCTCCT CGAGCAAAAA TGAACCAGCA GCGTGGGAGG 
CGTTTTAGGT CAGCAAAGGA GGCAGAAGAC AAAATTAAAA AGGCAATAGA GAAGGGAGAA 
ACTCTTCCTA CAGAGGCCAG ATTTGATTCC AACTGTATCA CACCAGGAAC TGAATTTATG 
GCCAGGTTAC ATGAACATCT GAAGTATTTT GTAAATATGA AAATTTCCAC AGACAAGTCA 
TGGCAAGGAG TTACCATCTA CTTCTCAGGC CATGAGACTC CTGGAGAAGG AGAGCATAAA 
ATCATGGAAT TTATCAGATC CGAGAAAGCA AAGCCAGATC ATGATCCAAA CACCAGACAC 
TGTCTTTATG GTTTAGATGC TGACTTGATT ATGCTTGGAT TAACAAGTCA TGAGGCACAT 
TTTTCTCTCT TAAGAGAAGA AGTTCGATTT GGTGGCAAAA AAACACAACG GGTATGTGCT 
CCAGAAGAAA CTACATTTCA CCTTCTACAC TTGTCTTTAA TGAGAGAGTA TATTGACTAT 
GAGTTTTCAG TATTAAAAGA AAAGATCACA TTTAAATATG ATATTGAAAG GATAATAGAT 
GATTGGATTT TGATGGGGTT TCTTGTTGGT AATGATTTTA TCCCTCATCT ACCTCATTTA 
CATATTAATC ATGATGCACT GCCTCTTCTT TATGGAACAT ATGTTACCAT CCTGCCAGAA 
CTTGGGGGTT ATATTAATGA AAGTGGGCAC CTCAACTTAC CTCGATTTGA GAAATACCTT 
GTGAAACTAT CAGATTTTGA TCGGGAGCAC TTCAGTGAAG TTTTTGTGGA CCTAAAATGG 
TTTGAAAGCA AAGTTGGTAA CAAGTACCTC AATGAAGCAG CAGGTGTCGC AGCAGAAGAA 
GCCAGGAACT ACAAGGAAAA GAAAAAGTTA AAGGGCCAGG AAAATTCTCT GTGTTGGACT 
GCTTTAGACA AAAATGAAGG CGAAATGATA ACTTCTAAGG ATAATTTAGA AGATGAGACT 
GAAGATGATG ACCTATTTGA AACTGAGTTT AGACAATATA AAAGAACATA TTACATGACG 
AAGATGGGGG TTGACGTAGT ATCTGATGAC TTTCTGGCTG ATCAAGCTGC ATGTTATGTT 
CAGGCAATAC AGTGGATTTT GCACTATTAC TATCATGGAG TTCAGTCCTG GAGCTGGTAT 
TATCCTTATC ATTATGCACC TTTCCTGTCT GATATACACA ACATCAGTAC ACTCAAAATC 
CATTTTGAAC TAGGAAAACC TTTTAAGCCA TTTGAACAGC TTCTTGCTGT ACTTCCAGCA 
GCCAGCAAAA ATTTACTTCC TGCATGCTAC CAGCATTTGA TGACCAATGA AGACTCACCA 
ATTATAGAAT ATTACCCACC TGATTTTAAA ACTGACCTAA ATGGGAAACA ACAGGAATGG 
GAAGCTGTGG TGTTAATCCC TTTTATTGAT GAGAAGCGAT TATTGGAAGC CATGGAGACA 
TGTAACCACT CCCTCAAAAA GGAAGAGAGG AAAAGAAACC AACATAGTGA GTGCCTAATG 
TGCTGGTATG ATAGAGACAC AGAGTTTATC TATCCTTCTC CATGGCCAGA AAAGTTCCCT 
GCCATAGAAC GATGTTGTAC AAGGTATAAA ATAATATCCT TAGATGCTTG GCGTGTAGAC 
ATAAACAAAA ACAAAATAAC CAGAATTGAC CAGAAAGCAT TATATTTCTG TGGATTTCCT 
ACTCTGAAAC ACATCAGACA CAAATTTTTT TTGAAGAAAA GTGGTGTTCA AGTATTCCAG 
CAAAGCAGTC GTGGAGAAAA CATGATGTTG GAAATCTTAG TGGATGCAGA ATCAGATGAA 
CTTACCGTAG AAAATGTAGC TTCATCAGTG CTTGGAAAAT CTGTCTTTGT TAATTGGCCT 
CACCTTGAGG AAGCTAGAGT CGTGGCTGTA TCAGATGGAG AAACTAAGTT TTACTTGGAA 
GAACCTCCAG GAACACAGAA GCTTTATTCA GGAAGAACTG CCCCACCATC TAAAGTGGTT 
CATCTTGGAG ATAAAGAACA ATCTAACTGG GCAAAAGAAG TACAAGGAAT TTCAGAACAC 
TACCTGAGAA GAAAAGGAAT AATAATAAAT GAAACATCTG CAGTTGTGTA TGCTCAGTTA 
CTCACAGGTC GTAAATATCA AATAAATCAA AATGGTGAAG TTCGTCTAGA GAAACAGTGG 
TCAAAACAAG TTGTTCCTTT TGTTTATCAA ACTATTGTCA AGGACATCCG AGCTTTCGAC 
TCCCGTTTCT CCAATATCAA AACATTGGAT GATTTGTTTC CTCTGAGAAG TATGGTCTTT 
ATGCTGGGAA CTCCCTATTA TGGCTGCACT GGAGAAGTTC AGGATTCAGG TGATGTGATT 
ACAGAAGGTA GGATTCGTGT GATTTTCAGC ATTCCATGTG AACCCAATCT TGATGCTTTA 
ATACAGAACC AGCATAAATA TTCTATAAAG TACAACCCAG GATATGTGTT GGCCAGTCGC 
CTTGGAGTGA GTGGATACCT TGTTTCAAGG TTTACAGGAA GTATTTTTAT TGGAAGAGGA 
TCTAGGAGAA ACCCTCATGG AGACCATAAA GCAAATGTGG GTTTAAATCT CAAATTCAAC 
AAGAAAAATG AGGAGGTACC TGGATATACT AAGAAAGTTG GAAGTGAATG GATGTATTCA 
TCTGCAGCAG AACAACTTCT GGCAGAGTAC TTAGAGAGAG CTCCAGAACT ATTTAGTTAT 
ATAGCCAAAA ATAGCCAAGA GGATGTGTTC TATGAAGATG ACATTTGGCC TGGAGAAAAT 
GAGAATGGTG CTGAAAAAGT TCAAGAAATT ATTACTTGGC TAAAAGGACA TCCTGTCAGT 
ACTTTATCTC GTTCTTCTTG TGATTTACAA ATTCTGGATG CAGCTATTGT TGAGAAAATT 
GAGGAAGAAG TCGAAAAGTG CAAGCAAAGA AAGAATAATA AGAAGGTGCG AGTAACAGTG 
AAACCCCATT TGCTATACAG ACCTTTAGAA CAGCAACATG GAGTCATTCC TGATCGGGAT 
GCAGAATTTT GTCTTTTTGA CCGTGTTGTA AATGTGAGAG AAAACTTCTC AGTTCCAGTT 
GGCCTTCGAG GCACCATCAT AGGAATAAAA GGAGCTAATA GAGAAGCCGA TGTACTATTT 
GAAGTATTAT TTGATGAAGA ATTTCCTGGA GGGTTAACAA TAAGATGCTC ACCTGGTAGA 
GGTTATCGAC TGCCAACAAG TGCCTTGGTG AACCTTTCTC ATGGGAGTCG CTCTGAAACT 
GGAAATCAGA AGTTGACAGC CATCGTAAAA CCACAACCAG CTGTACATCA ACATAGCTCA 
AGTTCATCAG TTTCCTCTGG GCATTTGGGA GCCCTCAACC ATTCCCCTCA ATCACTTTTT 
GTTCCTACTC AAGTACCTAC TAAAGATGAT GATGAATTCT GCAACATTTG GCAGTCCTTA 
CAGGGATCTG GAAAGATGCA ATACTTTCAG CCAACTATAC AAGAGAAGGG TGCAGTTCTA 
CCTCAAGAAA TAAGCCAAGT AAATCAACAT CATAAATCTG GCTTTAATGA CAACAGTGTT 
AAATATCAGC AAAGAAAACA TGACCCTCAC AGAAAATTTA AAGAAGAGTG TAAGAGTCCT 
AAAGCTGAGT GTTGGTCCCA AAAAATGTCC AATAAGCAGC CTAACTCTGG AATTGAGAAC 
TTTTTAGCAT CTTTGAATAT CTCCAAAGAA AATGAAGTAC AGTCATCTCA TCATGGGGAG 
CCTCCAAGTG AAGAGCATTT GTCACCACAG TCATTTGCCA TGAAGGGAAC ACGGATGCTT 
AAAGAAATTC TAAAAATTGA TGGCTCTAAC ACTGTGGACC ATAAGAATGA AATCAAACAG 
ATTGCTAATG AAATCCCTGT TTCCTCTAAC AGAAGAGATG AATATGGATT ACCCTCTCAG 
CCTAAACAAA ATAAGAAATT AGCATCTTAT ATGAACAAGC CTCACAGTGC TAATGAGTAC 
CATAATGTTC AGTCTATGGA CAATATGTGT TGGCCTGCCC CCAGCCAGAT CCCTCCTGTA 
TCCACACCAG TAACTGAACT TTCTCGAATT TGTTCCCTTG TTGGAATGCC ACAACCTGAT 
TTCTCCTTTC TTAGGATGCC ACAGACAATG ACCGTTTGCC AAGTAAAATT ATCTAATGGC 
TTACTGGTAC ATGGGCCACA GTGCCACTCT GAAAATGAAG CCAAAGAGAA AGCTGCACTT 
TTTGCTTTAC AACAGTTGGG CTCCTTAGGC ATGAATTTCC CTTTGCCTTC ACAAGTATTT 
GCAAATTATC CTTCAGCTGT ACCACCTGGA ACCATTCCTC CAGCCTTTCC CCCACCTACT 
GCTAATATAA TGCCTTCGTC GTCTCATCTC TTTGGCTCAA TGCCATGGGG ACCATCGGTG 
CCAGTTCCTG GGAAGCCCTT CCATCATACT TTATATTCTG GGACCATGCC CATGGCTGGG 
GGAATACCAG GGGGTGTGCA CAATCAGTTT ATACCTCTGC AGGTTACTAA AAAAAGGGTT 
GCAAACAAAA AGAACTTTGA GAATAAGGAA GCCCAGAGTT CTCAAGCCAC TCCAGTTCAG 
ACTAGCCAGC CAGATTCTTC CAACATTGTC AAAGTAAGTC CACGGGAGAG CTCATCAGCT 
TCTTTGAAGT CCTCTCCGAT TGCTCAACCT GCATCTTCTT TTCAAGTTGA AACTGCCTCT 
CAAGGCCATA GTATATCTCA CCATAAGTCA ACACCAATCT CTTCTTCAAG AAGAAAATCA 
AGAAAACTGG CTGTTAATTT TGGTGTTTCT AAACCTTCTG AGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001269786.1
CDS	119..5203
Translation	MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKIFTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKAIEKGETLPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHKIMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCAPEETTFHLLHLSLMREYIDYEFSVLKEKITFKYDIERIIDDWILMGFLVGNDFIPHLPHLHINHDALPLLYGTYVTILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKWFESKVGNKYLNEAAGVAAEEARNYKEKKKLKGQENSLCWTALDKNEGEMITSKDNLEDETEDDDLFETEFRQYKRTYYMTKMGVDVVSDDFLADQAACYVQAIQWILHYYYHGVQSWSWYYPYHYAPFLSDIHNISTLKIHFELGKPFKPFEQLLAVLPAASKNLLPACYQHLMTNEDSPIIEYYPPDFKTDLNGKQQEWEAVVLIPFIDEKRLLEAMETCNHSLKKEERKRNQHSECLMCWYDRDTEFIYPSPWPEKFPAIERCCTRYKIISLDAWRVDINKNKITRIDQKALYFCGFPTLKHIRHKFFLKKSGVQVFQQSSRGENMMLEILVDAESDELTVENVASSVLGKSVFVNWPHLEEARVVAVSDGETKFYLEEPPGTQKLYSGRTAPPSKVVHLGDKEQSNWAKEVQGISEHYLRRKGIIINETSAVVYAQLLTGRKYQINQNGEVRLEKQWSKQVVPFVYQTIVKDIRAFDSRFSNIKTLDDLFPLRSMVFMLGTPYYGCTGEVQDSGDVITEGRIRVIFSIPCEPNLDALIQNQHKYSIKYNPGYVLASRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFNKKNEEVPGYTKKVGSEWMYSSAAEQLLAEYLERAPELFSYIAKNSQEDVFYEDDIWPGENENGAEKVQEIITWLKGHPVSTLSRSSCDLQILDAAIVEKIEEEVEKCKQRKNNKKVRVTVKPHLLYRPLEQQHGVIPDRDAEFCLFDRVVNVRENFSVPVGLRGTIIGIKGANREADVLFEVLFDEEFPGGLTIRCSPGRGYRLPTSALVNLSHGSRSETGNQKLTAIVKPQPAVHQHSSSSSVSSGHLGALNHSPQSLFVPTQVPTKDDDEFCNIWQSLQGSGKMQYFQPTIQEKGAVLPQEISQVNQHHKSGFNDNSVKYQQRKHDPHRKFKEECKSPKAECWSQKMSNKQPNSGIENFLASLNISKENEVQSSHHGEPPSEEHLSPQSFAMKGTRMLKEILKIDGSNTVDHKNEIKQIANEIPVSSNRRDEYGLPSQPKQNKKLASYMNKPHSANEYHNVQSMDNMCWPAPSQIPPVSTPVTELSRICSLVGMPQPDFSFLRMPQTMTVCQVKLSNGLLVHGPQCHSENEAKEKAALFALQQLGSLGMNFPLPSQVFANYPSAVPPGTIPPAFPPPTANIMPSSSHLFGSMPWGPSVPVPGKPFHHTLYSGTMPMAGGIPGGVHNQFIPLQVTKKRVANKKNFENKEAQSSQATPVQTSQPDSSNIVKVSPRESSSASLKSSPIAQPASSFQVETASQGHSISHHKSTPISSSRRKSRKLAVNFGVSKPSE

Target ORF information:

RefSeq Version	NM_001282857.1
Organism	Homo sapiens(human)
Definition	Homo sapiens 5'-3' exoribonuclease 1 (XRN1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001282857.1

ORF Insert Sequence:

ATGGGAGTCC CCAAGTTTTA CAGATGGATC TCAGAGCGGT ATCCCTGTCT CAGCGAAGTG 
GTGAAAGAGC ATCAGATTCC TGAATTTGAC AACTTGTACC TGGATATGAA TGGAATTATA 
CATCAGTGCT CCCATCCTAA TGATGATGAT GTTCACTTTA GAATTTCAGA TGATAAAATC 
TTTACTGATA TTTTTCACTA CCTGGAGGTG TTGTTTCGCA TTATTAAACC CAGGAAAGTG 
TTCTTTATGG CTGTAGATGG TGTGGCTCCT CGAGCAAAAA TGAACCAGCA GCGTGGGAGG 
CGTTTTAGGT CAGCAAAGGA GGCAGAAGAC AAAATTAAAA AGGCAATAGA GAAGGGAGAA 
ACTCTTCCTA CAGAGGCCAG ATTTGATTCC AACTGTATCA CACCAGGAAC TGAATTTATG 
GCCAGGTTAC ATGAACATCT GAAGTATTTT GTAAATATGA AAATTTCCAC AGACAAGTCA 
TGGCAAGGAG TTACCATCTA CTTCTCAGGC CATGAGACTC CTGGAGAAGG AGAGCATAAA 
ATCATGGAAT TTATCAGATC CGAGAAAGCA AAGCCAGATC ATGATCCAAA CACCAGACAC 
TGTCTTTATG GTTTAGATGC TGACTTGATT ATGCTTGGAT TAACAAGTCA TGAGGCACAT 
TTTTCTCTCT TAAGAGAAGA AGTTCGATTT GGTGGCAAAA AAACACAACG GGTATGTGCT 
CCAGAAGAAA CTACATTTCA CCTTCTACAC TTGTCTTTAA TGAGAGAGTA TATTGACTAT 
GAGTTTTCAG TATTAAAAGA AAAGATCACA TTTAAATATG ATATTGAAAG GATAATAGAT 
GATTGGATTT TGATGGGGTT TCTTGTTGGT AATGATTTTA TCCCTCATCT ACCTCATTTA 
CATATTAATC ATGATGCACT GCCTCTTCTT TATGGAACAT ATGTTACCAT CCTGCCAGAA 
CTTGGGGGTT ATATTAATGA AAGTGGGCAC CTCAACTTAC CTCGATTTGA GAAATACCTT 
GTGAAACTAT CAGATTTTGA TCGGGAGCAC TTCAGTGAAG TTTTTGTGGA CCTAAAATGG 
TTTGAAAGCA AAGTTGGTAA CAAGTACCTC AATGAAGCAG CAGGTGTCGC AGCAGAAGAA 
GCCAGGAACT ACAAGGAAAA GAAAAAGTTA AAGGGCCAGG AAAATTCTCT GTGTTGGACT 
GCTTTAGACA AAAATGAAGG CGAAATGATA ACTTCTAAGG ATAATTTAGA AGATGAGACT 
GAAGATGATG ACCTATTTGA AACTGAGTTT AGACAATATA AAAGAACATA TTACATGACG 
AAGATGGGGG TTGACGTAGT ATCTGATGAC TTTCTGGCTG ATCAAGCTGC ATGTTATGTT 
CAGGCAATAC AGTGGATTTT GCACTATTAC TATCATGGAG TTCAGTCCTG GAGCTGGTAT 
TATCCTTATC ATTATGCACC TTTCCTGTCT GATATACACA ACATCAGTAC ACTCAAAATC 
CATTTTGAAC TAGGAAAACC TTTTAAGCCA TTTGAACAGC TTCTTGCTGT ACTTCCAGCA 
GCCAGCAAAA ATTTACTTCC TGCATGCTAC CAGCATTTGA TGACCAATGA AGACTCACCA 
ATTATAGAAT ATTACCCACC TGATTTTAAA ACTGACCTAA ATGGGAAACA ACAGGAATGG 
GAAGCTGTGG TGTTAATCCC TTTTATTGAT GAGAAGCGAT TATTGGAAGC CATGGAGACA 
TGTAACCACT CCCTCAAAAA GGAAGAGAGG AAAAGAAACC AACATAGTGA GTGCCTAATG 
TGCTGGTATG ATAGAGACAC AGAGTTTATC TATCCTTCTC CATGGCCAGA AAAGTTCCCT 
GCCATAGAAC GATGTTGTAC AAGGTATAAA ATAATATCCT TAGATGCTTG GCGTGTAGAC 
ATAAACAAAA ACAAAATAAC CAGAATTGAC CAGAAAGCAT TATATTTCTG TGGATTTCCT 
ACTCTGAAAC ACATCAGACA CAAATTTTTT TTGAAGAAAA GTGGTGTTCA AGTATTCCAG 
CAAAGCAGTC GTGGAGAAAA CATGATGTTG GAAATCTTAG TGGATGCAGA ATCAGATGAA 
CTTACCGTAG AAAATGTAGC TTCATCAGTG CTTGGAAAAT CTGTCTTTGT TAATTGGCCT 
CACCTTGAGG AAGCTAGAGT CGTGGCTGTA TCAGATGGAG AAACTAAGTT TTACTTGGAA 
GAACCTCCAG GAACACAGAA GCTTTATTCA GGAAGAACTG CCCCACCATC TAAAGTGGTT 
CATCTTGGAG ATAAAGAACA ATCTAACTGG GCAAAAGAAG TACAAGGAAT TTCAGAACAC 
TACCTGAGAA GAAAAGGAAT AATAATAAAT GAAACATCTG CAGTTGTGTA TGCTCAGTTA 
CTCACAGGTC GTAAATATCA AATAAATCAA AATGGTGAAG TTCGTCTAGA GAAACAGTGG 
TCAAAACAAG TTGTTCCTTT TGTTTATCAA ACTATTGTCA AGGACATCCG AGCTTTCGAC 
TCCCGTTTCT CCAATATCAA AACATTGGAT GATTTGTTTC CTCTGAGAAG TATGGTCTTT 
ATGCTGGGAA CTCCCTATTA TGGCTGCACT GGAGAAGTTC AGGATTCAGG TGATGTGATT 
ACAGAAGGTA GGATTCGTGT GATTTTCAGC ATTCCATGTG AACCCAATCT TGATGCTTTA 
ATACAGAACC AGCATAAATA TTCTATAAAG TACAACCCAG GATATGTGTT GGCCAGTCGC 
CTTGGAGTGA GTGGATACCT TGTTTCAAGG TTTACAGGAA GTATTTTTAT TGGAAGAGGA 
TCTAGGAGAA ACCCTCATGG AGACCATAAA GCAAATGTGG GTTTAAATCT CAAATTCAAC 
AAGAAAAATG AGGAGGTACC TGGATATACT AAGAAAGTTG GAAGTGAATG GATGTATTCA 
TCTGCAGCAG AACAACTTCT GGCAGAGTAC TTAGAGAGAG CTCCAGAACT ATTTAGTTAT 
ATAGCCAAAA ATAGCCAAGA GGATGTGTTC TATGAAGATG ACATTTGGCC TGGAGAAAAT 
GAGAATGGTG CTGAAAAAGT TCAAGAAATT ATTACTTGGC TAAAAGGACA TCCTGTCAGT 
ACTTTATCTC GTTCTTCTTG TGATTTACAA ATTCTGGATG CAGCTATTGT TGAGAAAATT 
GAGGAAGAAG TCGAAAAGTG CAAGCAAAGA AAGAATAATA AGAAGGTGCG AGTAACAGTG 
AAACCCCATT TGCTATACAG ACCTTTAGAA CAGCAACATG GAGTCATTCC TGATCGGGAT 
GCAGAATTTT GTCTTTTTGA CCGTGTTGTA AATGTGAGAG AAAACTTCTC AGTTCCAGTT 
GGCCTTCGAG GCACCATCAT AGGAATAAAA GGAGCTAATA GAGAAGCCGA TGTACTATTT 
GAAGTATTAT TTGATGAAGA ATTTCCTGGA GGGTTAACAA TAAGATGCTC ACCTGGTAGA 
GGTTATCGAC TGCCAACAAG TGCCTTGGTG AACCTTTCTC ATGGGAGTCG CTCTGAAACT 
GGAAATCAGA AGTTGACAGC CATCGTAAAA CCACAACCAG CTGTACATCA ACATAGCTCA 
AGTTCATCAG TTTCCTCTGG GCATTTGGGA GCCCTCAACC ATTCCCCTCA ATCACTTTTT 
GTTCCTACTC AAGTACCTAC TAAAGATGAT GATGAATTCT GCAACATTTG GCAGTCCTTA 
CAGGGATCTG GAAAGATGCA ATACTTTCAG CCAACTATAC AAGAGAAGGG TGCAGTTCTA 
CCTCAAGAAA TAAGCCAAGT AAATCAACAT CATAAATCTG GCTTTAATGA CAACAGTGTT 
AAATATCAGC AAAGAAAACA TGACCCTCAC AGAAAATTTA AAGAAGAGTG TAAGAGTCCT 
AAAGCTGAGT GTTGGTCCCA AAAAATGTCC AATAAGCAGC CTAACTCTGG AATTGAGAAC 
TTTTTAGCAT CTTTGAATAT CTCCAAAGAA AATGAAGTAC AGTCATCTCA TCATGGGGAG 
CCTCCAAGTG AAGAGCATTT GTCACCACAG TCATTTGCCA TGAAGGGAAC ACGGATGCTT 
AAAGAAATTC TAAAAATTGA TGGCTCTAAC ACTGTGGACC ATAAGAATGA AATCAAACAG 
ATTGCTAATG AAATCCCTGT TTCCTCTAAC AGAAGAGATG AATATGGATT ACCCTCTCAG 
CCTAAACAAA ATAAGAAATT AGCATCTTAT ATGAACAAGC CTCACAGTGC TAATGAGTAC 
CATAATGTTC AGTCTATGGA CAATATGTGT TGGCCTGCCC CCAGCCAGAT CCCTCCTGTA 
TCCACACCAG TAACTGAACT TTCTCGAATT TGTTCCCTTG TTGGAATGCC ACAACCTGAT 
TTCTCCTTTC TTAGGATGCC ACAGACAATG ACCGTTTGCC AAGTAAAATT ATCTAATGGC 
TTACTGGTAC ATGGGCCACA GTGCCACTCT GAAAATGAAG CCAAAGAGAA AGCTGCACTT 
TTTGCTTTAC AACAGTTGGG CTCCTTAGGC ATGAATTTCC CTTTGCCTTC ACAAGTATTT 
GCAAATTATC CTTCAGCTGT ACCACCTGGA ACCATTCCTC CAGCCTTTCC CCCACCTACT 
GCTAATATAA TGCCTTCGTC GTCTCATCTC TTTGGCTCAA TGCCATGGGG ACCATCGGTG 
CCAGTTCCTG GGAAGCCCTT CCATCATACT TTATATTCTG GGACCATGCC CATGGCTGGG 
GGAATACCAG GGGGTGTGCA CAATCAGTTT ATACCTCTGC AGGTTACTAA AAAAAGGGTT 
GCAAACAAAA AGAACTTTGA GAATAAGGAA GCCCAGAGTT CTCAAGCCAC TCCAGTTCAG 
ACTAGCCAGC CAGATTCTTC CAACATTGTC AAAGTAAGTC CACGGGAGAG CTCATCAGCT 
TCTTTGAAGT CCTCTCCGAT TGCTCAACCT GCATCTTCTT TTCAAGTTGA AACTGCCTCT 
CAAGGCCATA GTATATCTCA CCATAAGTCA ACACCAATCT CTTCTTCAAG AAGAAAATCA 
AGAAAACTGG CTGTTAATTT TGGTGTTTCT AAACCTTCTG AGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

XRN1 ( NM_019001.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_061874.3 Homo sapiens 5'-3' exoribonuclease 1 (XRN1), transcript variant 1, mRNA.

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CloneID	OHu08448
Clone ID Related Accession (Same CDS sequence)	NM_019001.5 , NM_019001.4
Accession Version	NM_019001.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 5121bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-15
Organism	Homo sapiens(human)
Product	5'-3' exoribonuclease 1 isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK096177.1, AY137776.1, AL133623.1 and AC023508.16. On Jun 2, 2019 this sequence version replaced NM_019001.4. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BX640905.1, AY137776.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGAGTCC CCAAGTTTTA CAGATGGATC TCAGAGCGGT ATCCCTGTCT CAGCGAAGTG 
GTGAAAGAGC ATCAGATTCC TGAATTTGAC AACTTGTACC TGGATATGAA TGGAATTATA 
CATCAGTGCT CCCATCCTAA TGATGATGAT GTTCACTTTA GAATTTCAGA TGATAAAATC 
TTTACTGATA TTTTTCACTA CCTGGAGGTG TTGTTTCGCA TTATTAAACC CAGGAAAGTG 
TTCTTTATGG CTGTAGATGG TGTGGCTCCT CGAGCAAAAA TGAACCAGCA GCGTGGGAGG 
CGTTTTAGGT CAGCAAAGGA GGCAGAAGAC AAAATTAAAA AGGCAATAGA GAAGGGAGAA 
ACTCTTCCTA CAGAGGCCAG ATTTGATTCC AACTGTATCA CACCAGGAAC TGAATTTATG 
GCCAGGTTAC ATGAACATCT GAAGTATTTT GTAAATATGA AAATTTCCAC AGACAAGTCA 
TGGCAAGGAG TTACCATCTA CTTCTCAGGC CATGAGACTC CTGGAGAAGG AGAGCATAAA 
ATCATGGAAT TTATCAGATC CGAGAAAGCA AAGCCAGATC ATGATCCAAA CACCAGACAC 
TGTCTTTATG GTTTAGATGC TGACTTGATT ATGCTTGGAT TAACAAGTCA TGAGGCACAT 
TTTTCTCTCT TAAGAGAAGA AGTTCGATTT GGTGGCAAAA AAACACAACG GGTATGTGCT 
CCAGAAGAAA CTACATTTCA CCTTCTACAC TTGTCTTTAA TGAGAGAGTA TATTGACTAT 
GAGTTTTCAG TATTAAAAGA AAAGATCACA TTTAAATATG ATATTGAAAG GATAATAGAT 
GATTGGATTT TGATGGGGTT TCTTGTTGGT AATGATTTTA TCCCTCATCT ACCTCATTTA 
CATATTAATC ATGATGCACT GCCTCTTCTT TATGGAACAT ATGTTACCAT CCTGCCAGAA 
CTTGGGGGTT ATATTAATGA AAGTGGGCAC CTCAACTTAC CTCGATTTGA GAAATACCTT 
GTGAAACTAT CAGATTTTGA TCGGGAGCAC TTCAGTGAAG TTTTTGTGGA CCTAAAATGG 
TTTGAAAGCA AAGTTGGTAA CAAGTACCTC AATGAAGCAG CAGGTGTCGC AGCAGAAGAA 
GCCAGGAACT ACAAGGAAAA GAAAAAGTTA AAGGGCCAGG AAAATTCTCT GTGTTGGACT 
GCTTTAGACA AAAATGAAGG CGAAATGATA ACTTCTAAGG ATAATTTAGA AGATGAGACT 
GAAGATGATG ACCTATTTGA AACTGAGTTT AGACAATATA AAAGAACATA TTACATGACG 
AAGATGGGGG TTGACGTAGT ATCTGATGAC TTTCTGGCTG ATCAAGCTGC ATGTTATGTT 
CAGGCAATAC AGTGGATTTT GCACTATTAC TATCATGGAG TTCAGTCCTG GAGCTGGTAT 
TATCCTTATC ATTATGCACC TTTCCTGTCT GATATACACA ACATCAGTAC ACTCAAAATC 
CATTTTGAAC TAGGAAAACC TTTTAAGCCA TTTGAACAGC TTCTTGCTGT ACTTCCAGCA 
GCCAGCAAAA ATTTACTTCC TGCATGCTAC CAGCATTTGA TGACCAATGA AGACTCACCA 
ATTATAGAAT ATTACCCACC TGATTTTAAA ACTGACCTAA ATGGGAAACA ACAGGAATGG 
GAAGCTGTGG TGTTAATCCC TTTTATTGAT GAGAAGCGAT TATTGGAAGC CATGGAGACA 
TGTAACCACT CCCTCAAAAA GGAAGAGAGG AAAAGAAACC AACATAGTGA GTGCCTAATG 
TGCTGGTATG ATAGAGACAC AGAGTTTATC TATCCTTCTC CATGGCCAGA AAAGTTCCCT 
GCCATAGAAC GATGTTGTAC AAGGTATAAA ATAATATCCT TAGATGCTTG GCGTGTAGAC 
ATAAACAAAA ACAAAATAAC CAGAATTGAC CAGAAAGCAT TATATTTCTG TGGATTTCCT 
ACTCTGAAAC ACATCAGACA CAAATTTTTT TTGAAGAAAA GTGGTGTTCA AGTATTCCAG 
CAAAGCAGTC GTGGAGAAAA CATGATGTTG GAAATCTTAG TGGATGCAGA ATCAGATGAA 
CTTACCGTAG AAAATGTAGC TTCATCAGTG CTTGGAAAAT CTGTCTTTGT TAATTGGCCT 
CACCTTGAGG AAGCTAGAGT CGTGGCTGTA TCAGATGGAG AAACTAAGTT TTACTTGGAA 
GAACCTCCAG GAACACAGAA GCTTTATTCA GGAAGAACTG CCCCACCATC TAAAGTGGTT 
CATCTTGGAG ATAAAGAACA ATCTAACTGG GCAAAAGAAG TACAAGGAAT TTCAGAACAC 
TACCTGAGAA GAAAAGGAAT AATAATAAAT GAAACATCTG CAGTTGTGTA TGCTCAGTTA 
CTCACAGGTC GTAAATATCA AATAAATCAA AATGGTGAAG TTCGTCTAGA GAAACAGTGG 
TCAAAACAAG TTGTTCCTTT TGTTTATCAA ACTATTGTCA AGGACATCCG AGCTTTCGAC 
TCCCGTTTCT CCAATATCAA AACATTGGAT GATTTGTTTC CTCTGAGAAG TATGGTCTTT 
ATGCTGGGAA CTCCCTATTA TGGCTGCACT GGAGAAGTTC AGGATTCAGG TGATGTGATT 
ACAGAAGGTA GGATTCGTGT GATTTTCAGC ATTCCATGTG AACCCAATCT TGATGCTTTA 
ATACAGAACC AGCATAAATA TTCTATAAAG TACAACCCAG GATATGTGTT GGCCAGTCGC 
CTTGGAGTGA GTGGATACCT TGTTTCAAGG TTTACAGGAA GTATTTTTAT TGGAAGAGGA 
TCTAGGAGAA ACCCTCATGG AGACCATAAA GCAAATGTGG GTTTAAATCT CAAATTCAAC 
AAGAAAAATG AGGAGGTACC TGGATATACT AAGAAAGTTG GAAGTGAATG GATGTATTCA 
TCTGCAGCAG AACAACTTCT GGCAGAGTAC TTAGAGAGAG CTCCAGAACT ATTTAGTTAT 
ATAGCCAAAA ATAGCCAAGA GGATGTGTTC TATGAAGATG ACATTTGGCC TGGAGAAAAT 
GAGAATGGTG CTGAAAAAGT TCAAGAAATT ATTACTTGGC TAAAAGGACA TCCTGTCAGT 
ACTTTATCTC GTTCTTCTTG TGATTTACAA ATTCTGGATG CAGCTATTGT TGAGAAAATT 
GAGGAAGAAG TCGAAAAGTG CAAGCAAAGA AAGAATAATA AGAAGGTGCG AGTAACAGTG 
AAACCCCATT TGCTATACAG ACCTTTAGAA CAGCAACATG GAGTCATTCC TGATCGGGAT 
GCAGAATTTT GTCTTTTTGA CCGTGTTGTA AATGTGAGAG AAAACTTCTC AGTTCCAGTT 
GGCCTTCGAG GCACCATCAT AGGAATAAAA GGAGCTAATA GAGAAGCCGA TGTACTATTT 
GAAGTATTAT TTGATGAAGA ATTTCCTGGA GGGTTAACAA TAAGATGCTC ACCTGGTAGA 
GGTTATCGAC TGCCAACAAG TGCCTTGGTG AACCTTTCTC ATGGGAGTCG CTCTGAAACT 
GGAAATCAGA AGTTGACAGC CATCGTAAAA CCACAACCAG CTGTACATCA ACATAGCTCA 
AGTTCATCAG TTTCCTCTGG GCATTTGGGA GCCCTCAACC ATTCCCCTCA ATCACTTTTT 
GTTCCTACTC AAGTACCTAC TAAAGATGAT GATGAATTCT GCAACATTTG GCAGTCCTTA 
CAGGGATCTG GAAAGATGCA ATACTTTCAG CCAACTATAC AAGAGAAGGG TGCAGTTCTA 
CCTCAAGAAA TAAGCCAAGT AAATCAACAT CATAAATCTG GCTTTAATGA CAACAGTGTT 
AAATATCAGC AAAGAAAACA TGACCCTCAC AGAAAATTTA AAGAAGAGTG TAAGAGTCCT 
AAAGCTGAGT GTTGGTCCCA AAAAATGTCC AATAAGCAGC CTAACTCTGG AATTGAGAAC 
TTTTTAGCAT CTTTGAATAT CTCCAAAGAA AATGAAGTAC AGTCATCTCA TCATGGGGAG 
CCTCCAAGTG AAGAGCATTT GTCACCACAG TCATTTGCCA TGGGAACACG GATGCTTAAA 
GAAATTCTAA AAATTGATGG CTCTAACACT GTGGACCATA AGAATGAAAT CAAACAGATT 
GCTAATGAAA TCCCTGTTTC CTCTAACAGA AGAGATGAAT ATGGATTACC CTCTCAGCCT 
AAACAAAATA AGAAATTAGC ATCTTATATG AACAAGCCTC ACAGTGCTAA TGAGTACCAT 
AATGTTCAGT CTATGGACAA TATGTGTTGG CCTGCCCCCA GCCAGATCCC TCCTGTATCC 
ACACCAGTAA CTGAACTTTC TCGAATTTGT TCCCTTGTTG GAATGCCACA ACCTGATTTC 
TCCTTTCTTA GGATGCCACA GACAATGACC GTTTGCCAAG TAAAATTATC TAATGGCTTA 
CTGGTACATG GGCCACAGTG CCACTCTGAA AATGAAGCCA AAGAGAAAGC TGCACTTTTT 
GCTTTACAAC AGTTGGGCTC CTTAGGCATG AATTTCCCTT TGCCTTCACA AGTATTTGCA 
AATTATCCTT CAGCTGTACC ACCTGGAACC ATTCCTCCAG CCTTTCCCCC ACCTACTGGC 
TGGGATCACT ATGGAAGCAA CTATGCATTG GGGGCAGCTA ATATAATGCC TTCGTCGTCT 
CATCTCTTTG GCTCAATGCC ATGGGGACCA TCGGTGCCAG TTCCTGGGAA GCCCTTCCAT 
CATACTTTAT ATTCTGGGAC CATGCCCATG GCTGGGGGAA TACCAGGGGG TGTGCACAAT 
CAGTTTATAC CTCTGCAGGT TACTAAAAAA AGGGTTGCAA ACAAAAAGAA CTTTGAGAAT 
AAGGAAGCCC AGAGTTCTCA AGCCACTCCA GTTCAGACTA GCCAGCCAGA TTCTTCCAAC 
ATTGTCAAAG TAAGTCCACG GGAGAGCTCA TCAGCTTCTT TGAAGTCCTC TCCGATTGCT 
CAACCTGCAT CTTCTTTTCA AGTTGAAACT GCCTCTCAAG GCCATAGTAT ATCTCACCAT 
AAGTCAACAC CAATCTCTTC TTCAAGAAGA AAATCAAGAA AACTGGCTGT TAATTTTGGT 
GTTTCTAAAC CTTCTGAGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_061874.3
CDS	94..5214
Translation	MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKIFTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKAIEKGETLPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHKIMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCAPEETTFHLLHLSLMREYIDYEFSVLKEKITFKYDIERIIDDWILMGFLVGNDFIPHLPHLHINHDALPLLYGTYVTILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKWFESKVGNKYLNEAAGVAAEEARNYKEKKKLKGQENSLCWTALDKNEGEMITSKDNLEDETEDDDLFETEFRQYKRTYYMTKMGVDVVSDDFLADQAACYVQAIQWILHYYYHGVQSWSWYYPYHYAPFLSDIHNISTLKIHFELGKPFKPFEQLLAVLPAASKNLLPACYQHLMTNEDSPIIEYYPPDFKTDLNGKQQEWEAVVLIPFIDEKRLLEAMETCNHSLKKEERKRNQHSECLMCWYDRDTEFIYPSPWPEKFPAIERCCTRYKIISLDAWRVDINKNKITRIDQKALYFCGFPTLKHIRHKFFLKKSGVQVFQQSSRGENMMLEILVDAESDELTVENVASSVLGKSVFVNWPHLEEARVVAVSDGETKFYLEEPPGTQKLYSGRTAPPSKVVHLGDKEQSNWAKEVQGISEHYLRRKGIIINETSAVVYAQLLTGRKYQINQNGEVRLEKQWSKQVVPFVYQTIVKDIRAFDSRFSNIKTLDDLFPLRSMVFMLGTPYYGCTGEVQDSGDVITEGRIRVIFSIPCEPNLDALIQNQHKYSIKYNPGYVLASRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFNKKNEEVPGYTKKVGSEWMYSSAAEQLLAEYLERAPELFSYIAKNSQEDVFYEDDIWPGENENGAEKVQEIITWLKGHPVSTLSRSSCDLQILDAAIVEKIEEEVEKCKQRKNNKKVRVTVKPHLLYRPLEQQHGVIPDRDAEFCLFDRVVNVRENFSVPVGLRGTIIGIKGANREADVLFEVLFDEEFPGGLTIRCSPGRGYRLPTSALVNLSHGSRSETGNQKLTAIVKPQPAVHQHSSSSSVSSGHLGALNHSPQSLFVPTQVPTKDDDEFCNIWQSLQGSGKMQYFQPTIQEKGAVLPQEISQVNQHHKSGFNDNSVKYQQRKHDPHRKFKEECKSPKAECWSQKMSNKQPNSGIENFLASLNISKENEVQSSHHGEPPSEEHLSPQSFAMGTRMLKEILKIDGSNTVDHKNEIKQIANEIPVSSNRRDEYGLPSQPKQNKKLASYMNKPHSANEYHNVQSMDNMCWPAPSQIPPVSTPVTELSRICSLVGMPQPDFSFLRMPQTMTVCQVKLSNGLLVHGPQCHSENEAKEKAALFALQQLGSLGMNFPLPSQVFANYPSAVPPGTIPPAFPPPTGWDHYGSNYALGAANIMPSSSHLFGSMPWGPSVPVPGKPFHHTLYSGTMPMAGGIPGGVHNQFIPLQVTKKRVANKKNFENKEAQSSQATPVQTSQPDSSNIVKVSPRESSSASLKSSPIAQPASSFQVETASQGHSISHHKSTPISSSRRKSRKLAVNFGVSKPSE

Target ORF information:

RefSeq Version	NM_019001.5
Organism	Homo sapiens(human)
Definition	Homo sapiens 5'-3' exoribonuclease 1 (XRN1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019001.5

ORF Insert Sequence:

ATGGGAGTCC CCAAGTTTTA CAGATGGATC TCAGAGCGGT ATCCCTGTCT CAGCGAAGTG 
GTGAAAGAGC ATCAGATTCC TGAATTTGAC AACTTGTACC TGGATATGAA TGGAATTATA 
CATCAGTGCT CCCATCCTAA TGATGATGAT GTTCACTTTA GAATTTCAGA TGATAAAATC 
TTTACTGATA TTTTTCACTA CCTGGAGGTG TTGTTTCGCA TTATTAAACC CAGGAAAGTG 
TTCTTTATGG CTGTAGATGG TGTGGCTCCT CGAGCAAAAA TGAACCAGCA GCGTGGGAGG 
CGTTTTAGGT CAGCAAAGGA GGCAGAAGAC AAAATTAAAA AGGCAATAGA GAAGGGAGAA 
ACTCTTCCTA CAGAGGCCAG ATTTGATTCC AACTGTATCA CACCAGGAAC TGAATTTATG 
GCCAGGTTAC ATGAACATCT GAAGTATTTT GTAAATATGA AAATTTCCAC AGACAAGTCA 
TGGCAAGGAG TTACCATCTA CTTCTCAGGC CATGAGACTC CTGGAGAAGG AGAGCATAAA 
ATCATGGAAT TTATCAGATC CGAGAAAGCA AAGCCAGATC ATGATCCAAA CACCAGACAC 
TGTCTTTATG GTTTAGATGC TGACTTGATT ATGCTTGGAT TAACAAGTCA TGAGGCACAT 
TTTTCTCTCT TAAGAGAAGA AGTTCGATTT GGTGGCAAAA AAACACAACG GGTATGTGCT 
CCAGAAGAAA CTACATTTCA CCTTCTACAC TTGTCTTTAA TGAGAGAGTA TATTGACTAT 
GAGTTTTCAG TATTAAAAGA AAAGATCACA TTTAAATATG ATATTGAAAG GATAATAGAT 
GATTGGATTT TGATGGGGTT TCTTGTTGGT AATGATTTTA TCCCTCATCT ACCTCATTTA 
CATATTAATC ATGATGCACT GCCTCTTCTT TATGGAACAT ATGTTACCAT CCTGCCAGAA 
CTTGGGGGTT ATATTAATGA AAGTGGGCAC CTCAACTTAC CTCGATTTGA GAAATACCTT 
GTGAAACTAT CAGATTTTGA TCGGGAGCAC TTCAGTGAAG TTTTTGTGGA CCTAAAATGG 
TTTGAAAGCA AAGTTGGTAA CAAGTACCTC AATGAAGCAG CAGGTGTCGC AGCAGAAGAA 
GCCAGGAACT ACAAGGAAAA GAAAAAGTTA AAGGGCCAGG AAAATTCTCT GTGTTGGACT 
GCTTTAGACA AAAATGAAGG CGAAATGATA ACTTCTAAGG ATAATTTAGA AGATGAGACT 
GAAGATGATG ACCTATTTGA AACTGAGTTT AGACAATATA AAAGAACATA TTACATGACG 
AAGATGGGGG TTGACGTAGT ATCTGATGAC TTTCTGGCTG ATCAAGCTGC ATGTTATGTT 
CAGGCAATAC AGTGGATTTT GCACTATTAC TATCATGGAG TTCAGTCCTG GAGCTGGTAT 
TATCCTTATC ATTATGCACC TTTCCTGTCT GATATACACA ACATCAGTAC ACTCAAAATC 
CATTTTGAAC TAGGAAAACC TTTTAAGCCA TTTGAACAGC TTCTTGCTGT ACTTCCAGCA 
GCCAGCAAAA ATTTACTTCC TGCATGCTAC CAGCATTTGA TGACCAATGA AGACTCACCA 
ATTATAGAAT ATTACCCACC TGATTTTAAA ACTGACCTAA ATGGGAAACA ACAGGAATGG 
GAAGCTGTGG TGTTAATCCC TTTTATTGAT GAGAAGCGAT TATTGGAAGC CATGGAGACA 
TGTAACCACT CCCTCAAAAA GGAAGAGAGG AAAAGAAACC AACATAGTGA GTGCCTAATG 
TGCTGGTATG ATAGAGACAC AGAGTTTATC TATCCTTCTC CATGGCCAGA AAAGTTCCCT 
GCCATAGAAC GATGTTGTAC AAGGTATAAA ATAATATCCT TAGATGCTTG GCGTGTAGAC 
ATAAACAAAA ACAAAATAAC CAGAATTGAC CAGAAAGCAT TATATTTCTG TGGATTTCCT 
ACTCTGAAAC ACATCAGACA CAAATTTTTT TTGAAGAAAA GTGGTGTTCA AGTATTCCAG 
CAAAGCAGTC GTGGAGAAAA CATGATGTTG GAAATCTTAG TGGATGCAGA ATCAGATGAA 
CTTACCGTAG AAAATGTAGC TTCATCAGTG CTTGGAAAAT CTGTCTTTGT TAATTGGCCT 
CACCTTGAGG AAGCTAGAGT CGTGGCTGTA TCAGATGGAG AAACTAAGTT TTACTTGGAA 
GAACCTCCAG GAACACAGAA GCTTTATTCA GGAAGAACTG CCCCACCATC TAAAGTGGTT 
CATCTTGGAG ATAAAGAACA ATCTAACTGG GCAAAAGAAG TACAAGGAAT TTCAGAACAC 
TACCTGAGAA GAAAAGGAAT AATAATAAAT GAAACATCTG CAGTTGTGTA TGCTCAGTTA 
CTCACAGGTC GTAAATATCA AATAAATCAA AATGGTGAAG TTCGTCTAGA GAAACAGTGG 
TCAAAACAAG TTGTTCCTTT TGTTTATCAA ACTATTGTCA AGGACATCCG AGCTTTCGAC 
TCCCGTTTCT CCAATATCAA AACATTGGAT GATTTGTTTC CTCTGAGAAG TATGGTCTTT 
ATGCTGGGAA CTCCCTATTA TGGCTGCACT GGAGAAGTTC AGGATTCAGG TGATGTGATT 
ACAGAAGGTA GGATTCGTGT GATTTTCAGC ATTCCATGTG AACCCAATCT TGATGCTTTA 
ATACAGAACC AGCATAAATA TTCTATAAAG TACAACCCAG GATATGTGTT GGCCAGTCGC 
CTTGGAGTGA GTGGATACCT TGTTTCAAGG TTTACAGGAA GTATTTTTAT TGGAAGAGGA 
TCTAGGAGAA ACCCTCATGG AGACCATAAA GCAAATGTGG GTTTAAATCT CAAATTCAAC 
AAGAAAAATG AGGAGGTACC TGGATATACT AAGAAAGTTG GAAGTGAATG GATGTATTCA 
TCTGCAGCAG AACAACTTCT GGCAGAGTAC TTAGAGAGAG CTCCAGAACT ATTTAGTTAT 
ATAGCCAAAA ATAGCCAAGA GGATGTGTTC TATGAAGATG ACATTTGGCC TGGAGAAAAT 
GAGAATGGTG CTGAAAAAGT TCAAGAAATT ATTACTTGGC TAAAAGGACA TCCTGTCAGT 
ACTTTATCTC GTTCTTCTTG TGATTTACAA ATTCTGGATG CAGCTATTGT TGAGAAAATT 
GAGGAAGAAG TCGAAAAGTG CAAGCAAAGA AAGAATAATA AGAAGGTGCG AGTAACAGTG 
AAACCCCATT TGCTATACAG ACCTTTAGAA CAGCAACATG GAGTCATTCC TGATCGGGAT 
GCAGAATTTT GTCTTTTTGA CCGTGTTGTA AATGTGAGAG AAAACTTCTC AGTTCCAGTT 
GGCCTTCGAG GCACCATCAT AGGAATAAAA GGAGCTAATA GAGAAGCCGA TGTACTATTT 
GAAGTATTAT TTGATGAAGA ATTTCCTGGA GGGTTAACAA TAAGATGCTC ACCTGGTAGA 
GGTTATCGAC TGCCAACAAG TGCCTTGGTG AACCTTTCTC ATGGGAGTCG CTCTGAAACT 
GGAAATCAGA AGTTGACAGC CATCGTAAAA CCACAACCAG CTGTACATCA ACATAGCTCA 
AGTTCATCAG TTTCCTCTGG GCATTTGGGA GCCCTCAACC ATTCCCCTCA ATCACTTTTT 
GTTCCTACTC AAGTACCTAC TAAAGATGAT GATGAATTCT GCAACATTTG GCAGTCCTTA 
CAGGGATCTG GAAAGATGCA ATACTTTCAG CCAACTATAC AAGAGAAGGG TGCAGTTCTA 
CCTCAAGAAA TAAGCCAAGT AAATCAACAT CATAAATCTG GCTTTAATGA CAACAGTGTT 
AAATATCAGC AAAGAAAACA TGACCCTCAC AGAAAATTTA AAGAAGAGTG TAAGAGTCCT 
AAAGCTGAGT GTTGGTCCCA AAAAATGTCC AATAAGCAGC CTAACTCTGG AATTGAGAAC 
TTTTTAGCAT CTTTGAATAT CTCCAAAGAA AATGAAGTAC AGTCATCTCA TCATGGGGAG 
CCTCCAAGTG AAGAGCATTT GTCACCACAG TCATTTGCCA TGGGAACACG GATGCTTAAA 
GAAATTCTAA AAATTGATGG CTCTAACACT GTGGACCATA AGAATGAAAT CAAACAGATT 
GCTAATGAAA TCCCTGTTTC CTCTAACAGA AGAGATGAAT ATGGATTACC CTCTCAGCCT 
AAACAAAATA AGAAATTAGC ATCTTATATG AACAAGCCTC ACAGTGCTAA TGAGTACCAT 
AATGTTCAGT CTATGGACAA TATGTGTTGG CCTGCCCCCA GCCAGATCCC TCCTGTATCC 
ACACCAGTAA CTGAACTTTC TCGAATTTGT TCCCTTGTTG GAATGCCACA ACCTGATTTC 
TCCTTTCTTA GGATGCCACA GACAATGACC GTTTGCCAAG TAAAATTATC TAATGGCTTA 
CTGGTACATG GGCCACAGTG CCACTCTGAA AATGAAGCCA AAGAGAAAGC TGCACTTTTT 
GCTTTACAAC AGTTGGGCTC CTTAGGCATG AATTTCCCTT TGCCTTCACA AGTATTTGCA 
AATTATCCTT CAGCTGTACC ACCTGGAACC ATTCCTCCAG CCTTTCCCCC ACCTACTGGC 
TGGGATCACT ATGGAAGCAA CTATGCATTG GGGGCAGCTA ATATAATGCC TTCGTCGTCT 
CATCTCTTTG GCTCAATGCC ATGGGGACCA TCGGTGCCAG TTCCTGGGAA GCCCTTCCAT 
CATACTTTAT ATTCTGGGAC CATGCCCATG GCTGGGGGAA TACCAGGGGG TGTGCACAAT 
CAGTTTATAC CTCTGCAGGT TACTAAAAAA AGGGTTGCAA ACAAAAAGAA CTTTGAGAAT 
AAGGAAGCCC AGAGTTCTCA AGCCACTCCA GTTCAGACTA GCCAGCCAGA TTCTTCCAAC 
ATTGTCAAAG TAAGTCCACG GGAGAGCTCA TCAGCTTCTT TGAAGTCCTC TCCGATTGCT 
CAACCTGCAT CTTCTTTTCA AGTTGAAACT GCCTCTCAAG GCCATAGTAT ATCTCACCAT 
AAGTCAACAC CAATCTCTTC TTCAAGAAGA AAATCAAGAA AACTGGCTGT TAATTTTGGT 
GTTTCTAAAC CTTCTGAGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

XRN1 ( NM_019001.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_061874.3 Homo sapiens 5'-3' exoribonuclease 1 (XRN1), transcript variant 1, mRNA.

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CloneID	OHu08448
Clone ID Related Accession (Same CDS sequence)	NM_019001.5 , NM_019001.4
Accession Version	NM_019001.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 5121bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Homo sapiens(human)
Product	5'-3' exoribonuclease 1 isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK096177.1, AY137776.1, AL133623.1 and AC023508.16. On Sep 20, 2013 this sequence version replaced NM_019001.3. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BX640905.1, AY137776.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGAGTCC CCAAGTTTTA CAGATGGATC TCAGAGCGGT ATCCCTGTCT CAGCGAAGTG 
GTGAAAGAGC ATCAGATTCC TGAATTTGAC AACTTGTACC TGGATATGAA TGGAATTATA 
CATCAGTGCT CCCATCCTAA TGATGATGAT GTTCACTTTA GAATTTCAGA TGATAAAATC 
TTTACTGATA TTTTTCACTA CCTGGAGGTG TTGTTTCGCA TTATTAAACC CAGGAAAGTG 
TTCTTTATGG CTGTAGATGG TGTGGCTCCT CGAGCAAAAA TGAACCAGCA GCGTGGGAGG 
CGTTTTAGGT CAGCAAAGGA GGCAGAAGAC AAAATTAAAA AGGCAATAGA GAAGGGAGAA 
ACTCTTCCTA CAGAGGCCAG ATTTGATTCC AACTGTATCA CACCAGGAAC TGAATTTATG 
GCCAGGTTAC ATGAACATCT GAAGTATTTT GTAAATATGA AAATTTCCAC AGACAAGTCA 
TGGCAAGGAG TTACCATCTA CTTCTCAGGC CATGAGACTC CTGGAGAAGG AGAGCATAAA 
ATCATGGAAT TTATCAGATC CGAGAAAGCA AAGCCAGATC ATGATCCAAA CACCAGACAC 
TGTCTTTATG GTTTAGATGC TGACTTGATT ATGCTTGGAT TAACAAGTCA TGAGGCACAT 
TTTTCTCTCT TAAGAGAAGA AGTTCGATTT GGTGGCAAAA AAACACAACG GGTATGTGCT 
CCAGAAGAAA CTACATTTCA CCTTCTACAC TTGTCTTTAA TGAGAGAGTA TATTGACTAT 
GAGTTTTCAG TATTAAAAGA AAAGATCACA TTTAAATATG ATATTGAAAG GATAATAGAT 
GATTGGATTT TGATGGGGTT TCTTGTTGGT AATGATTTTA TCCCTCATCT ACCTCATTTA 
CATATTAATC ATGATGCACT GCCTCTTCTT TATGGAACAT ATGTTACCAT CCTGCCAGAA 
CTTGGGGGTT ATATTAATGA AAGTGGGCAC CTCAACTTAC CTCGATTTGA GAAATACCTT 
GTGAAACTAT CAGATTTTGA TCGGGAGCAC TTCAGTGAAG TTTTTGTGGA CCTAAAATGG 
TTTGAAAGCA AAGTTGGTAA CAAGTACCTC AATGAAGCAG CAGGTGTCGC AGCAGAAGAA 
GCCAGGAACT ACAAGGAAAA GAAAAAGTTA AAGGGCCAGG AAAATTCTCT GTGTTGGACT 
GCTTTAGACA AAAATGAAGG CGAAATGATA ACTTCTAAGG ATAATTTAGA AGATGAGACT 
GAAGATGATG ACCTATTTGA AACTGAGTTT AGACAATATA AAAGAACATA TTACATGACG 
AAGATGGGGG TTGACGTAGT ATCTGATGAC TTTCTGGCTG ATCAAGCTGC ATGTTATGTT 
CAGGCAATAC AGTGGATTTT GCACTATTAC TATCATGGAG TTCAGTCCTG GAGCTGGTAT 
TATCCTTATC ATTATGCACC TTTCCTGTCT GATATACACA ACATCAGTAC ACTCAAAATC 
CATTTTGAAC TAGGAAAACC TTTTAAGCCA TTTGAACAGC TTCTTGCTGT ACTTCCAGCA 
GCCAGCAAAA ATTTACTTCC TGCATGCTAC CAGCATTTGA TGACCAATGA AGACTCACCA 
ATTATAGAAT ATTACCCACC TGATTTTAAA ACTGACCTAA ATGGGAAACA ACAGGAATGG 
GAAGCTGTGG TGTTAATCCC TTTTATTGAT GAGAAGCGAT TATTGGAAGC CATGGAGACA 
TGTAACCACT CCCTCAAAAA GGAAGAGAGG AAAAGAAACC AACATAGTGA GTGCCTAATG 
TGCTGGTATG ATAGAGACAC AGAGTTTATC TATCCTTCTC CATGGCCAGA AAAGTTCCCT 
GCCATAGAAC GATGTTGTAC AAGGTATAAA ATAATATCCT TAGATGCTTG GCGTGTAGAC 
ATAAACAAAA ACAAAATAAC CAGAATTGAC CAGAAAGCAT TATATTTCTG TGGATTTCCT 
ACTCTGAAAC ACATCAGACA CAAATTTTTT TTGAAGAAAA GTGGTGTTCA AGTATTCCAG 
CAAAGCAGTC GTGGAGAAAA CATGATGTTG GAAATCTTAG TGGATGCAGA ATCAGATGAA 
CTTACCGTAG AAAATGTAGC TTCATCAGTG CTTGGAAAAT CTGTCTTTGT TAATTGGCCT 
CACCTTGAGG AAGCTAGAGT CGTGGCTGTA TCAGATGGAG AAACTAAGTT TTACTTGGAA 
GAACCTCCAG GAACACAGAA GCTTTATTCA GGAAGAACTG CCCCACCATC TAAAGTGGTT 
CATCTTGGAG ATAAAGAACA ATCTAACTGG GCAAAAGAAG TACAAGGAAT TTCAGAACAC 
TACCTGAGAA GAAAAGGAAT AATAATAAAT GAAACATCTG CAGTTGTGTA TGCTCAGTTA 
CTCACAGGTC GTAAATATCA AATAAATCAA AATGGTGAAG TTCGTCTAGA GAAACAGTGG 
TCAAAACAAG TTGTTCCTTT TGTTTATCAA ACTATTGTCA AGGACATCCG AGCTTTCGAC 
TCCCGTTTCT CCAATATCAA AACATTGGAT GATTTGTTTC CTCTGAGAAG TATGGTCTTT 
ATGCTGGGAA CTCCCTATTA TGGCTGCACT GGAGAAGTTC AGGATTCAGG TGATGTGATT 
ACAGAAGGTA GGATTCGTGT GATTTTCAGC ATTCCATGTG AACCCAATCT TGATGCTTTA 
ATACAGAACC AGCATAAATA TTCTATAAAG TACAACCCAG GATATGTGTT GGCCAGTCGC 
CTTGGAGTGA GTGGATACCT TGTTTCAAGG TTTACAGGAA GTATTTTTAT TGGAAGAGGA 
TCTAGGAGAA ACCCTCATGG AGACCATAAA GCAAATGTGG GTTTAAATCT CAAATTCAAC 
AAGAAAAATG AGGAGGTACC TGGATATACT AAGAAAGTTG GAAGTGAATG GATGTATTCA 
TCTGCAGCAG AACAACTTCT GGCAGAGTAC TTAGAGAGAG CTCCAGAACT ATTTAGTTAT 
ATAGCCAAAA ATAGCCAAGA GGATGTGTTC TATGAAGATG ACATTTGGCC TGGAGAAAAT 
GAGAATGGTG CTGAAAAAGT TCAAGAAATT ATTACTTGGC TAAAAGGACA TCCTGTCAGT 
ACTTTATCTC GTTCTTCTTG TGATTTACAA ATTCTGGATG CAGCTATTGT TGAGAAAATT 
GAGGAAGAAG TCGAAAAGTG CAAGCAAAGA AAGAATAATA AGAAGGTGCG AGTAACAGTG 
AAACCCCATT TGCTATACAG ACCTTTAGAA CAGCAACATG GAGTCATTCC TGATCGGGAT 
GCAGAATTTT GTCTTTTTGA CCGTGTTGTA AATGTGAGAG AAAACTTCTC AGTTCCAGTT 
GGCCTTCGAG GCACCATCAT AGGAATAAAA GGAGCTAATA GAGAAGCCGA TGTACTATTT 
GAAGTATTAT TTGATGAAGA ATTTCCTGGA GGGTTAACAA TAAGATGCTC ACCTGGTAGA 
GGTTATCGAC TGCCAACAAG TGCCTTGGTG AACCTTTCTC ATGGGAGTCG CTCTGAAACT 
GGAAATCAGA AGTTGACAGC CATCGTAAAA CCACAACCAG CTGTACATCA ACATAGCTCA 
AGTTCATCAG TTTCCTCTGG GCATTTGGGA GCCCTCAACC ATTCCCCTCA ATCACTTTTT 
GTTCCTACTC AAGTACCTAC TAAAGATGAT GATGAATTCT GCAACATTTG GCAGTCCTTA 
CAGGGATCTG GAAAGATGCA ATACTTTCAG CCAACTATAC AAGAGAAGGG TGCAGTTCTA 
CCTCAAGAAA TAAGCCAAGT AAATCAACAT CATAAATCTG GCTTTAATGA CAACAGTGTT 
AAATATCAGC AAAGAAAACA TGACCCTCAC AGAAAATTTA AAGAAGAGTG TAAGAGTCCT 
AAAGCTGAGT GTTGGTCCCA AAAAATGTCC AATAAGCAGC CTAACTCTGG AATTGAGAAC 
TTTTTAGCAT CTTTGAATAT CTCCAAAGAA AATGAAGTAC AGTCATCTCA TCATGGGGAG 
CCTCCAAGTG AAGAGCATTT GTCACCACAG TCATTTGCCA TGGGAACACG GATGCTTAAA 
GAAATTCTAA AAATTGATGG CTCTAACACT GTGGACCATA AGAATGAAAT CAAACAGATT 
GCTAATGAAA TCCCTGTTTC CTCTAACAGA AGAGATGAAT ATGGATTACC CTCTCAGCCT 
AAACAAAATA AGAAATTAGC ATCTTATATG AACAAGCCTC ACAGTGCTAA TGAGTACCAT 
AATGTTCAGT CTATGGACAA TATGTGTTGG CCTGCCCCCA GCCAGATCCC TCCTGTATCC 
ACACCAGTAA CTGAACTTTC TCGAATTTGT TCCCTTGTTG GAATGCCACA ACCTGATTTC 
TCCTTTCTTA GGATGCCACA GACAATGACC GTTTGCCAAG TAAAATTATC TAATGGCTTA 
CTGGTACATG GGCCACAGTG CCACTCTGAA AATGAAGCCA AAGAGAAAGC TGCACTTTTT 
GCTTTACAAC AGTTGGGCTC CTTAGGCATG AATTTCCCTT TGCCTTCACA AGTATTTGCA 
AATTATCCTT CAGCTGTACC ACCTGGAACC ATTCCTCCAG CCTTTCCCCC ACCTACTGGC 
TGGGATCACT ATGGAAGCAA CTATGCATTG GGGGCAGCTA ATATAATGCC TTCGTCGTCT 
CATCTCTTTG GCTCAATGCC ATGGGGACCA TCGGTGCCAG TTCCTGGGAA GCCCTTCCAT 
CATACTTTAT ATTCTGGGAC CATGCCCATG GCTGGGGGAA TACCAGGGGG TGTGCACAAT 
CAGTTTATAC CTCTGCAGGT TACTAAAAAA AGGGTTGCAA ACAAAAAGAA CTTTGAGAAT 
AAGGAAGCCC AGAGTTCTCA AGCCACTCCA GTTCAGACTA GCCAGCCAGA TTCTTCCAAC 
ATTGTCAAAG TAAGTCCACG GGAGAGCTCA TCAGCTTCTT TGAAGTCCTC TCCGATTGCT 
CAACCTGCAT CTTCTTTTCA AGTTGAAACT GCCTCTCAAG GCCATAGTAT ATCTCACCAT 
AAGTCAACAC CAATCTCTTC TTCAAGAAGA AAATCAAGAA AACTGGCTGT TAATTTTGGT 
GTTTCTAAAC CTTCTGAGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_061874.3
CDS	119..5239
Translation	MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKIFTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKAIEKGETLPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHKIMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCAPEETTFHLLHLSLMREYIDYEFSVLKEKITFKYDIERIIDDWILMGFLVGNDFIPHLPHLHINHDALPLLYGTYVTILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKWFESKVGNKYLNEAAGVAAEEARNYKEKKKLKGQENSLCWTALDKNEGEMITSKDNLEDETEDDDLFETEFRQYKRTYYMTKMGVDVVSDDFLADQAACYVQAIQWILHYYYHGVQSWSWYYPYHYAPFLSDIHNISTLKIHFELGKPFKPFEQLLAVLPAASKNLLPACYQHLMTNEDSPIIEYYPPDFKTDLNGKQQEWEAVVLIPFIDEKRLLEAMETCNHSLKKEERKRNQHSECLMCWYDRDTEFIYPSPWPEKFPAIERCCTRYKIISLDAWRVDINKNKITRIDQKALYFCGFPTLKHIRHKFFLKKSGVQVFQQSSRGENMMLEILVDAESDELTVENVASSVLGKSVFVNWPHLEEARVVAVSDGETKFYLEEPPGTQKLYSGRTAPPSKVVHLGDKEQSNWAKEVQGISEHYLRRKGIIINETSAVVYAQLLTGRKYQINQNGEVRLEKQWSKQVVPFVYQTIVKDIRAFDSRFSNIKTLDDLFPLRSMVFMLGTPYYGCTGEVQDSGDVITEGRIRVIFSIPCEPNLDALIQNQHKYSIKYNPGYVLASRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFNKKNEEVPGYTKKVGSEWMYSSAAEQLLAEYLERAPELFSYIAKNSQEDVFYEDDIWPGENENGAEKVQEIITWLKGHPVSTLSRSSCDLQILDAAIVEKIEEEVEKCKQRKNNKKVRVTVKPHLLYRPLEQQHGVIPDRDAEFCLFDRVVNVRENFSVPVGLRGTIIGIKGANREADVLFEVLFDEEFPGGLTIRCSPGRGYRLPTSALVNLSHGSRSETGNQKLTAIVKPQPAVHQHSSSSSVSSGHLGALNHSPQSLFVPTQVPTKDDDEFCNIWQSLQGSGKMQYFQPTIQEKGAVLPQEISQVNQHHKSGFNDNSVKYQQRKHDPHRKFKEECKSPKAECWSQKMSNKQPNSGIENFLASLNISKENEVQSSHHGEPPSEEHLSPQSFAMGTRMLKEILKIDGSNTVDHKNEIKQIANEIPVSSNRRDEYGLPSQPKQNKKLASYMNKPHSANEYHNVQSMDNMCWPAPSQIPPVSTPVTELSRICSLVGMPQPDFSFLRMPQTMTVCQVKLSNGLLVHGPQCHSENEAKEKAALFALQQLGSLGMNFPLPSQVFANYPSAVPPGTIPPAFPPPTGWDHYGSNYALGAANIMPSSSHLFGSMPWGPSVPVPGKPFHHTLYSGTMPMAGGIPGGVHNQFIPLQVTKKRVANKKNFENKEAQSSQATPVQTSQPDSSNIVKVSPRESSSASLKSSPIAQPASSFQVETASQGHSISHHKSTPISSSRRKSRKLAVNFGVSKPSE

Target ORF information:

RefSeq Version	NM_019001.4
Organism	Homo sapiens(human)
Definition	Homo sapiens 5'-3' exoribonuclease 1 (XRN1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019001.4

ORF Insert Sequence:

ATGGGAGTCC CCAAGTTTTA CAGATGGATC TCAGAGCGGT ATCCCTGTCT CAGCGAAGTG 
GTGAAAGAGC ATCAGATTCC TGAATTTGAC AACTTGTACC TGGATATGAA TGGAATTATA 
CATCAGTGCT CCCATCCTAA TGATGATGAT GTTCACTTTA GAATTTCAGA TGATAAAATC 
TTTACTGATA TTTTTCACTA CCTGGAGGTG TTGTTTCGCA TTATTAAACC CAGGAAAGTG 
TTCTTTATGG CTGTAGATGG TGTGGCTCCT CGAGCAAAAA TGAACCAGCA GCGTGGGAGG 
CGTTTTAGGT CAGCAAAGGA GGCAGAAGAC AAAATTAAAA AGGCAATAGA GAAGGGAGAA 
ACTCTTCCTA CAGAGGCCAG ATTTGATTCC AACTGTATCA CACCAGGAAC TGAATTTATG 
GCCAGGTTAC ATGAACATCT GAAGTATTTT GTAAATATGA AAATTTCCAC AGACAAGTCA 
TGGCAAGGAG TTACCATCTA CTTCTCAGGC CATGAGACTC CTGGAGAAGG AGAGCATAAA 
ATCATGGAAT TTATCAGATC CGAGAAAGCA AAGCCAGATC ATGATCCAAA CACCAGACAC 
TGTCTTTATG GTTTAGATGC TGACTTGATT ATGCTTGGAT TAACAAGTCA TGAGGCACAT 
TTTTCTCTCT TAAGAGAAGA AGTTCGATTT GGTGGCAAAA AAACACAACG GGTATGTGCT 
CCAGAAGAAA CTACATTTCA CCTTCTACAC TTGTCTTTAA TGAGAGAGTA TATTGACTAT 
GAGTTTTCAG TATTAAAAGA AAAGATCACA TTTAAATATG ATATTGAAAG GATAATAGAT 
GATTGGATTT TGATGGGGTT TCTTGTTGGT AATGATTTTA TCCCTCATCT ACCTCATTTA 
CATATTAATC ATGATGCACT GCCTCTTCTT TATGGAACAT ATGTTACCAT CCTGCCAGAA 
CTTGGGGGTT ATATTAATGA AAGTGGGCAC CTCAACTTAC CTCGATTTGA GAAATACCTT 
GTGAAACTAT CAGATTTTGA TCGGGAGCAC TTCAGTGAAG TTTTTGTGGA CCTAAAATGG 
TTTGAAAGCA AAGTTGGTAA CAAGTACCTC AATGAAGCAG CAGGTGTCGC AGCAGAAGAA 
GCCAGGAACT ACAAGGAAAA GAAAAAGTTA AAGGGCCAGG AAAATTCTCT GTGTTGGACT 
GCTTTAGACA AAAATGAAGG CGAAATGATA ACTTCTAAGG ATAATTTAGA AGATGAGACT 
GAAGATGATG ACCTATTTGA AACTGAGTTT AGACAATATA AAAGAACATA TTACATGACG 
AAGATGGGGG TTGACGTAGT ATCTGATGAC TTTCTGGCTG ATCAAGCTGC ATGTTATGTT 
CAGGCAATAC AGTGGATTTT GCACTATTAC TATCATGGAG TTCAGTCCTG GAGCTGGTAT 
TATCCTTATC ATTATGCACC TTTCCTGTCT GATATACACA ACATCAGTAC ACTCAAAATC 
CATTTTGAAC TAGGAAAACC TTTTAAGCCA TTTGAACAGC TTCTTGCTGT ACTTCCAGCA 
GCCAGCAAAA ATTTACTTCC TGCATGCTAC CAGCATTTGA TGACCAATGA AGACTCACCA 
ATTATAGAAT ATTACCCACC TGATTTTAAA ACTGACCTAA ATGGGAAACA ACAGGAATGG 
GAAGCTGTGG TGTTAATCCC TTTTATTGAT GAGAAGCGAT TATTGGAAGC CATGGAGACA 
TGTAACCACT CCCTCAAAAA GGAAGAGAGG AAAAGAAACC AACATAGTGA GTGCCTAATG 
TGCTGGTATG ATAGAGACAC AGAGTTTATC TATCCTTCTC CATGGCCAGA AAAGTTCCCT 
GCCATAGAAC GATGTTGTAC AAGGTATAAA ATAATATCCT TAGATGCTTG GCGTGTAGAC 
ATAAACAAAA ACAAAATAAC CAGAATTGAC CAGAAAGCAT TATATTTCTG TGGATTTCCT 
ACTCTGAAAC ACATCAGACA CAAATTTTTT TTGAAGAAAA GTGGTGTTCA AGTATTCCAG 
CAAAGCAGTC GTGGAGAAAA CATGATGTTG GAAATCTTAG TGGATGCAGA ATCAGATGAA 
CTTACCGTAG AAAATGTAGC TTCATCAGTG CTTGGAAAAT CTGTCTTTGT TAATTGGCCT 
CACCTTGAGG AAGCTAGAGT CGTGGCTGTA TCAGATGGAG AAACTAAGTT TTACTTGGAA 
GAACCTCCAG GAACACAGAA GCTTTATTCA GGAAGAACTG CCCCACCATC TAAAGTGGTT 
CATCTTGGAG ATAAAGAACA ATCTAACTGG GCAAAAGAAG TACAAGGAAT TTCAGAACAC 
TACCTGAGAA GAAAAGGAAT AATAATAAAT GAAACATCTG CAGTTGTGTA TGCTCAGTTA 
CTCACAGGTC GTAAATATCA AATAAATCAA AATGGTGAAG TTCGTCTAGA GAAACAGTGG 
TCAAAACAAG TTGTTCCTTT TGTTTATCAA ACTATTGTCA AGGACATCCG AGCTTTCGAC 
TCCCGTTTCT CCAATATCAA AACATTGGAT GATTTGTTTC CTCTGAGAAG TATGGTCTTT 
ATGCTGGGAA CTCCCTATTA TGGCTGCACT GGAGAAGTTC AGGATTCAGG TGATGTGATT 
ACAGAAGGTA GGATTCGTGT GATTTTCAGC ATTCCATGTG AACCCAATCT TGATGCTTTA 
ATACAGAACC AGCATAAATA TTCTATAAAG TACAACCCAG GATATGTGTT GGCCAGTCGC 
CTTGGAGTGA GTGGATACCT TGTTTCAAGG TTTACAGGAA GTATTTTTAT TGGAAGAGGA 
TCTAGGAGAA ACCCTCATGG AGACCATAAA GCAAATGTGG GTTTAAATCT CAAATTCAAC 
AAGAAAAATG AGGAGGTACC TGGATATACT AAGAAAGTTG GAAGTGAATG GATGTATTCA 
TCTGCAGCAG AACAACTTCT GGCAGAGTAC TTAGAGAGAG CTCCAGAACT ATTTAGTTAT 
ATAGCCAAAA ATAGCCAAGA GGATGTGTTC TATGAAGATG ACATTTGGCC TGGAGAAAAT 
GAGAATGGTG CTGAAAAAGT TCAAGAAATT ATTACTTGGC TAAAAGGACA TCCTGTCAGT 
ACTTTATCTC GTTCTTCTTG TGATTTACAA ATTCTGGATG CAGCTATTGT TGAGAAAATT 
GAGGAAGAAG TCGAAAAGTG CAAGCAAAGA AAGAATAATA AGAAGGTGCG AGTAACAGTG 
AAACCCCATT TGCTATACAG ACCTTTAGAA CAGCAACATG GAGTCATTCC TGATCGGGAT 
GCAGAATTTT GTCTTTTTGA CCGTGTTGTA AATGTGAGAG AAAACTTCTC AGTTCCAGTT 
GGCCTTCGAG GCACCATCAT AGGAATAAAA GGAGCTAATA GAGAAGCCGA TGTACTATTT 
GAAGTATTAT TTGATGAAGA ATTTCCTGGA GGGTTAACAA TAAGATGCTC ACCTGGTAGA 
GGTTATCGAC TGCCAACAAG TGCCTTGGTG AACCTTTCTC ATGGGAGTCG CTCTGAAACT 
GGAAATCAGA AGTTGACAGC CATCGTAAAA CCACAACCAG CTGTACATCA ACATAGCTCA 
AGTTCATCAG TTTCCTCTGG GCATTTGGGA GCCCTCAACC ATTCCCCTCA ATCACTTTTT 
GTTCCTACTC AAGTACCTAC TAAAGATGAT GATGAATTCT GCAACATTTG GCAGTCCTTA 
CAGGGATCTG GAAAGATGCA ATACTTTCAG CCAACTATAC AAGAGAAGGG TGCAGTTCTA 
CCTCAAGAAA TAAGCCAAGT AAATCAACAT CATAAATCTG GCTTTAATGA CAACAGTGTT 
AAATATCAGC AAAGAAAACA TGACCCTCAC AGAAAATTTA AAGAAGAGTG TAAGAGTCCT 
AAAGCTGAGT GTTGGTCCCA AAAAATGTCC AATAAGCAGC CTAACTCTGG AATTGAGAAC 
TTTTTAGCAT CTTTGAATAT CTCCAAAGAA AATGAAGTAC AGTCATCTCA TCATGGGGAG 
CCTCCAAGTG AAGAGCATTT GTCACCACAG TCATTTGCCA TGGGAACACG GATGCTTAAA 
GAAATTCTAA AAATTGATGG CTCTAACACT GTGGACCATA AGAATGAAAT CAAACAGATT 
GCTAATGAAA TCCCTGTTTC CTCTAACAGA AGAGATGAAT ATGGATTACC CTCTCAGCCT 
AAACAAAATA AGAAATTAGC ATCTTATATG AACAAGCCTC ACAGTGCTAA TGAGTACCAT 
AATGTTCAGT CTATGGACAA TATGTGTTGG CCTGCCCCCA GCCAGATCCC TCCTGTATCC 
ACACCAGTAA CTGAACTTTC TCGAATTTGT TCCCTTGTTG GAATGCCACA ACCTGATTTC 
TCCTTTCTTA GGATGCCACA GACAATGACC GTTTGCCAAG TAAAATTATC TAATGGCTTA 
CTGGTACATG GGCCACAGTG CCACTCTGAA AATGAAGCCA AAGAGAAAGC TGCACTTTTT 
GCTTTACAAC AGTTGGGCTC CTTAGGCATG AATTTCCCTT TGCCTTCACA AGTATTTGCA 
AATTATCCTT CAGCTGTACC ACCTGGAACC ATTCCTCCAG CCTTTCCCCC ACCTACTGGC 
TGGGATCACT ATGGAAGCAA CTATGCATTG GGGGCAGCTA ATATAATGCC TTCGTCGTCT 
CATCTCTTTG GCTCAATGCC ATGGGGACCA TCGGTGCCAG TTCCTGGGAA GCCCTTCCAT 
CATACTTTAT ATTCTGGGAC CATGCCCATG GCTGGGGGAA TACCAGGGGG TGTGCACAAT 
CAGTTTATAC CTCTGCAGGT TACTAAAAAA AGGGTTGCAA ACAAAAAGAA CTTTGAGAAT 
AAGGAAGCCC AGAGTTCTCA AGCCACTCCA GTTCAGACTA GCCAGCCAGA TTCTTCCAAC 
ATTGTCAAAG TAAGTCCACG GGAGAGCTCA TCAGCTTCTT TGAAGTCCTC TCCGATTGCT 
CAACCTGCAT CTTCTTTTCA AGTTGAAACT GCCTCTCAAG GCCATAGTAT ATCTCACCAT 
AAGTCAACAC CAATCTCTTC TTCAAGAAGA AAATCAAGAA AACTGGCTGT TAATTTTGGT 
GTTTCTAAAC CTTCTGAGTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

XRN1 ( XM_011512919.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011511221.1 Homo sapiens 5'-3' exoribonuclease 1 (XRN1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu68345
Clone ID Related Accession (Same CDS sequence)	XM_011512919.2
Accession Version	XM_011512919.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 5124bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	5'-3' exoribonuclease 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011512919.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGAGTCC CCAAGTTTTA CAGATGGATC TCAGAGCGGT ATCCCTGTCT CAGCGAAGTG 
GTGAAAGAGC ATCAGATTCC TGAATTTGAC AACTTGTACC TGGATATGAA TGGAATTATA 
CATCAGTGCT CCCATCCTAA TGATGATGAT GTTCACTTTA GAATTTCAGA TGATAAAATC 
TTTACTGATA TTTTTCACTA CCTGGAGGTG TTGTTTCGCA TTATTAAACC CAGGAAAGTG 
TTCTTTATGG CTGTAGATGG TGTGGCTCCT CGAGCAAAAA TGAACCAGCA GCGTGGGAGG 
CGTTTTAGGT CAGCAAAGGA GGCAGAAGAC AAAATTAAAA AGGCAATAGA GAAGGGAGAA 
ACTCTTCCTA CAGAGGCCAG ATTTGATTCC AACTGTATCA CACCAGGAAC TGAATTTATG 
GCCAGGTTAC ATGAACATCT GAAGTATTTT GTAAATATGA AAATTTCCAC AGACAAGTCA 
TGGCAAGGAG TTACCATCTA CTTCTCAGGC CATGAGACTC CTGGAGAAGG AGAGCATAAA 
ATCATGGAAT TTATCAGATC CGAGAAAGCA AAGCCAGATC ATGATCCAAA CACCAGACAC 
TGTCTTTATG GTTTAGATGC TGACTTGATT ATGCTTGGAT TAACAAGTCA TGAGGCACAT 
TTTTCTCTCT TAAGAGAAGA AGTTCGATTT GGTGGCAAAA AAACACAACG GGTATGTGCT 
CCAGAAGAAA CTACATTTCA CCTTCTACAC TTGTCTTTAA TGAGAGAGTA TATTGACTAT 
GAGTTTTCAG TATTAAAAGA AAAGATCACA TTTAAATATG ATATTGAAAG GATAATAGAT 
GATTGGATTT TGATGGGGTT TCTTGTTGGT AATGATTTTA TCCCTCATCT ACCTCATTTA 
CATATTAATC ATGATGCACT GCCTCTTCTT TATGGAACAT ATGTTACCAT CCTGCCAGAA 
CTTGGGGGTT ATATTAATGA AAGTGGGCAC CTCAACTTAC CTCGATTTGA GAAATACCTT 
GTGAAACTAT CAGATTTTGA TCGGGAGCAC TTCAGTGAAG TTTTTGTGGA CCTAAAATGG 
TTTGAAAGCA AAGTTGGTAA CAAGTACCTC AATGAAGCAG CAGGTGTCGC AGCAGAAGAA 
GCCAGGAACT ACAAGGAAAA GAAAAAGTTA AAGGGCCAGG AAAATTCTCT GTGTTGGACT 
GCTTTAGACA AAAATGAAGG CGAAATGATA ACTTCTAAGG ATAATTTAGA AGATGAGACT 
GAAGATGATG ACCTATTTGA AACTGAGTTT AGACAATATA AAAGAACATA TTACATGACG 
AAGATGGGGG TTGACGTAGT ATCTGATGAC TTTCTGGCTG ATCAAGCTGC ATGTTATGTT 
CAGGCAATAC AGTGGATTTT GCACTATTAC TATCATGGAG TTCAGTCCTG GAGCTGGTAT 
TATCCTTATC ATTATGCACC TTTCCTGTCT GATATACACA ACATCAGTAC ACTCAAAATC 
CATTTTGAAC TAGGAAAACC TTTTAAGCCA TTTGAACAGC TTCTTGCTGT ACTTCCAGCA 
GCCAGCAAAA ATTTACTTCC TGCATGCTAC CAGCATTTGA TGACCAATGA AGACTCACCA 
ATTATAGAAT ATTACCCACC TGATTTTAAA ACTGACCTAA ATGGGAAACA ACAGGAATGG 
GAAGCTGTGG TGTTAATCCC TTTTATTGAT GAGAAGCGAT TATTGGAAGC CATGGAGACA 
TGTAACCACT CCCTCAAAAA GGAAGAGAGG AAAAGAAACC AACATAGTGA GTGCCTAATG 
TGCTGGTATG ATAGAGACAC AGAGTTTATC TATCCTTCTC CATGGCCAGA AAAGTTCCCT 
GCCATAGAAC GATGTTGTAC AAGGTATAAA ATAATATCCT TAGATGCTTG GCGTGTAGAC 
ATAAACAAAA ACAAAATAAC CAGAATTGAC CAGAAAGCAT TATATTTCTG TGGATTTCCT 
ACTCTGAAAC ACATCAGACA CAAATTTTTT TTGAAGAAAA GTGGTGTTCA AGTATTCCAG 
CAAAGCAGTC GTGGAGAAAA CATGATGTTG GAAATCTTAG TGGATGCAGA ATCAGATGAA 
CTTACCGTAG AAAATGTAGC TTCATCAGTG CTTGGAAAAT CTGTCTTTGT TAATTGGCCT 
CACCTTGAGG AAGCTAGAGT CGTGGCTGTA TCAGATGGAG AAACTAAGTT TTACTTGGAA 
GAACCTCCAG GAACACAGAA GCTTTATTCA GGAAGAACTG CCCCACCATC TAAAGTGGTT 
CATCTTGGAG ATAAAGAACA ATCTAACTGG GCAAAAGAAG TACAAGGAAT TTCAGAACAC 
TACCTGAGAA GAAAAGGAAT AATAATAAAT GAAACATCTG CAGTTGTGTA TGCTCAGTTA 
CTCACAGGTC GTAAATATCA AATAAATCAA AATGGTGAAG TTCGTCTAGA GAAACAGTGG 
TCAAAACAAG TTGTTCCTTT TGTTTATCAA ACTATTGTCA AGGACATCCG AGCTTTCGAC 
TCCCGTTTCT CCAATATCAA AACATTGGAT GATTTGTTTC CTCTGAGAAG TATGGTCTTT 
ATGCTGGGAA CTCCCTATTA TGGCTGCACT GGAGAAGTTC AGGATTCAGG TGATGTGATT 
ACAGAAGGTA GGATTCGTGT GATTTTCAGC ATTCCATGTG AACCCAATCT TGATGCTTTA 
ATACAGAACC AGCATAAATA TTCTATAAAG TACAACCCAG GATATGTGTT GGCCAGTCGC 
CTTGGAGTGA GTGGATACCT TGTTTCAAGG TTTACAGGAA GTATTTTTAT TGGAAGAGGA 
TCTAGGAGAA ACCCTCATGG AGACCATAAA GCAAATGTGG GTTTAAATCT CAAATTCAAC 
AAGAAAAATG AGGAGGTACC TGGATATACT AAGAAAGTTG GAAGTGAATG GATGTATTCA 
TCTGCAGCAG AACAACTTCT GGCAGAGTAC TTAGAGAGAG CTCCAGAACT ATTTAGTTAT 
ATAGCCAAAA ATAGCCAAGA GGATGTGTTC TATGAAGATG ACATTTGGCC TGGAGAAAAT 
GAGAATGGTG CTGAAAAAGT TCAAGAAATT ATTACTTGGC TAAAAGGACA TCCTGTCAGT 
ACTTTATCTC GTTCTTCTTG TGATTTACAA ATTCTGGATG CAGCTATTGT TGAGAAAATT 
GAGGAAGAAG TCGAAAAGTG CAAGCAAAGA AAGAATAATA AGAAGGTGCG AGTAACAGTG 
AAACCCCATT TGCTATACAG ACCTTTAGAA CAGCAACATG GAGTCATTCC TGATCGGGAT 
GCAGAATTTT GTCTTTTTGA CCGTGTTGTA AATGTGAGAG AAAACTTCTC AGTTCCAGTT 
GGCCTTCGAG GCACCATCAT AGGAATAAAA GGAGCTAATA GAGAAGCCGA TGTACTATTT 
GAAGTATTAT TTGATGAAGA ATTTCCTGGA GGGTTAACAA TAAGATGCTC ACCTGGTAGA 
GGTTATCGAC TGCCAACAAG TGCCTTGGTG AACCTTTCTC ATGGGAGTCG CTCTGAAACT 
GGAAATCAGA AGTTGACAGC CATCGTAAAA CCACAACCAG CTGTACATCA ACATAGCTCA 
AGTTCATCAG TTTCCTCTGG GCATTTGGGA GCCCTCAACC ATTCCCCTCA ATCACTTTTT 
GTTCCTACTC AAGTACCTAC TAAAGATGAT GATGAATTCT GCAACATTTG GCAGTCCTTA 
CAGGGATCTG GAAAGATGCA ATACTTTCAG CCAACTATAC AAGAGAAGGG TGCAGTTCTA 
CCTCAAGAAA TAAGCCAAGT AAATCAACAT CATAAATCTG GCTTTAATGA CAACAGTGTT 
AAATATCAGC AAAGAAAACA TGACCCTCAC AGAAAATTTA AAGAAGAGTG TAAGAGTCCT 
AAAGCTGAGT GTTGGTCCCA AAAAATGTCC AATAAGCAGC CTAACTCTGG AATTGAGAAC 
TTTTTAGCAT CTTTGAATAT CTCCAAAGAA AATGAAGTAC AGTCATCTCA TCATGGGGAG 
CCTCCAAGTG AAGAGCATTT GTCACCACAG TCATTTGCCA TGAAGGGAAC ACGGATGCTT 
AAAGAAATTC TAAAAATTGA TGGCTCTAAC ACTGTGGACC ATAAGAATGA AATCAAACAG 
ATTGCTAATG AAATCCCTGT TTCCTCTAAC AGAAGAGATG AATATGGATT ACCCTCTCAG 
CCTAAACAAA ATAAGAAATT AGCATCTTAT ATGAACAAGC CTCACAGTGC TAATGAGTAC 
CATAATGTTC AGTCTATGGA CAATATGTGT TGGCCTGCCC CCAGCCAGAT CCCTCCTGTA 
TCCACACCAG TAACTGAACT TTCTCGAATT TGTTCCCTTG TTGGAATGCC ACAACCTGAT 
TTCTCCTTTC TTAGGATGCC ACAGACAATG ACCGTTTGCC AAGTAAAATT ATCTAATGGC 
TTACTGGTAC ATGGGCCACA GTGCCACTCT GAAAATGAAG CCAAAGAGAA AGCTGCACTT 
TTTGCTTTAC AACAGTTGGG CTCCTTAGGC ATGAATTTCC CTTTGCCTTC ACAAGTATTT 
GCAAATTATC CTTCAGCTGT ACCACCTGGA ACCATTCCTC CAGCCTTTCC CCCACCTACT 
GGCTGGGATC ACTATGGAAG CAACTATGCA TTGGGGGCAG CTAATATAAT GCCTTCGTCG 
TCTCATCTCT TTGGCTCAAT GCCATGGGGA CCATCGGTGC CAGTTCCTGG GAAGCCCTTC 
CATCATACTT TATATTCTGG GACCATGCCC ATGGCTGGGG GAATACCAGG GGGTGTGCAC 
AATCAGTTTA TACCTCTGCA GGTTACTAAA AAAAGGGTTG CAAACAAAAA GAACTTTGAG 
AATAAGGAAG CCCAGAGTTC TCAAGCCACT CCAGTTCAGA CTAGCCAGCC AGATTCTTCC 
AACATTGTCA AAGTAAGTCC ACGGGAGAGC TCATCAGCTT CTTTGAAGTC CTCTCCGATT 
GCTCAACCTG CATCTTCTTT TCAAGTTGAA ACTGCCTCTC AAGGCCATAG TATATCTCAC 
CATAAGTCAA CACCAATCTC TTCTTCAAGA AGAAAATCAA GAAAACTGGC TGTTAATTTT 
GGTGTTTCTA AACCTTCTGA GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011511221.1
CDS	119..5242
Translation	MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKIFTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKAIEKGETLPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHKIMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCAPEETTFHLLHLSLMREYIDYEFSVLKEKITFKYDIERIIDDWILMGFLVGNDFIPHLPHLHINHDALPLLYGTYVTILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKWFESKVGNKYLNEAAGVAAEEARNYKEKKKLKGQENSLCWTALDKNEGEMITSKDNLEDETEDDDLFETEFRQYKRTYYMTKMGVDVVSDDFLADQAACYVQAIQWILHYYYHGVQSWSWYYPYHYAPFLSDIHNISTLKIHFELGKPFKPFEQLLAVLPAASKNLLPACYQHLMTNEDSPIIEYYPPDFKTDLNGKQQEWEAVVLIPFIDEKRLLEAMETCNHSLKKEERKRNQHSECLMCWYDRDTEFIYPSPWPEKFPAIERCCTRYKIISLDAWRVDINKNKITRIDQKALYFCGFPTLKHIRHKFFLKKSGVQVFQQSSRGENMMLEILVDAESDELTVENVASSVLGKSVFVNWPHLEEARVVAVSDGETKFYLEEPPGTQKLYSGRTAPPSKVVHLGDKEQSNWAKEVQGISEHYLRRKGIIINETSAVVYAQLLTGRKYQINQNGEVRLEKQWSKQVVPFVYQTIVKDIRAFDSRFSNIKTLDDLFPLRSMVFMLGTPYYGCTGEVQDSGDVITEGRIRVIFSIPCEPNLDALIQNQHKYSIKYNPGYVLASRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFNKKNEEVPGYTKKVGSEWMYSSAAEQLLAEYLERAPELFSYIAKNSQEDVFYEDDIWPGENENGAEKVQEIITWLKGHPVSTLSRSSCDLQILDAAIVEKIEEEVEKCKQRKNNKKVRVTVKPHLLYRPLEQQHGVIPDRDAEFCLFDRVVNVRENFSVPVGLRGTIIGIKGANREADVLFEVLFDEEFPGGLTIRCSPGRGYRLPTSALVNLSHGSRSETGNQKLTAIVKPQPAVHQHSSSSSVSSGHLGALNHSPQSLFVPTQVPTKDDDEFCNIWQSLQGSGKMQYFQPTIQEKGAVLPQEISQVNQHHKSGFNDNSVKYQQRKHDPHRKFKEECKSPKAECWSQKMSNKQPNSGIENFLASLNISKENEVQSSHHGEPPSEEHLSPQSFAMKGTRMLKEILKIDGSNTVDHKNEIKQIANEIPVSSNRRDEYGLPSQPKQNKKLASYMNKPHSANEYHNVQSMDNMCWPAPSQIPPVSTPVTELSRICSLVGMPQPDFSFLRMPQTMTVCQVKLSNGLLVHGPQCHSENEAKEKAALFALQQLGSLGMNFPLPSQVFANYPSAVPPGTIPPAFPPPTGWDHYGSNYALGAANIMPSSSHLFGSMPWGPSVPVPGKPFHHTLYSGTMPMAGGIPGGVHNQFIPLQVTKKRVANKKNFENKEAQSSQATPVQTSQPDSSNIVKVSPRESSSASLKSSPIAQPASSFQVETASQGHSISHHKSTPISSSRRKSRKLAVNFGVSKPSE

Target ORF information:

RefSeq Version	XM_011512919.2
Organism	Homo sapiens(human)
Definition	Homo sapiens 5'-3' exoribonuclease 1 (XRN1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011512919.2

ORF Insert Sequence:

ATGGGAGTCC CCAAGTTTTA CAGATGGATC TCAGAGCGGT ATCCCTGTCT CAGCGAAGTG 
GTGAAAGAGC ATCAGATTCC TGAATTTGAC AACTTGTACC TGGATATGAA TGGAATTATA 
CATCAGTGCT CCCATCCTAA TGATGATGAT GTTCACTTTA GAATTTCAGA TGATAAAATC 
TTTACTGATA TTTTTCACTA CCTGGAGGTG TTGTTTCGCA TTATTAAACC CAGGAAAGTG 
TTCTTTATGG CTGTAGATGG TGTGGCTCCT CGAGCAAAAA TGAACCAGCA GCGTGGGAGG 
CGTTTTAGGT CAGCAAAGGA GGCAGAAGAC AAAATTAAAA AGGCAATAGA GAAGGGAGAA 
ACTCTTCCTA CAGAGGCCAG ATTTGATTCC AACTGTATCA CACCAGGAAC TGAATTTATG 
GCCAGGTTAC ATGAACATCT GAAGTATTTT GTAAATATGA AAATTTCCAC AGACAAGTCA 
TGGCAAGGAG TTACCATCTA CTTCTCAGGC CATGAGACTC CTGGAGAAGG AGAGCATAAA 
ATCATGGAAT TTATCAGATC CGAGAAAGCA AAGCCAGATC ATGATCCAAA CACCAGACAC 
TGTCTTTATG GTTTAGATGC TGACTTGATT ATGCTTGGAT TAACAAGTCA TGAGGCACAT 
TTTTCTCTCT TAAGAGAAGA AGTTCGATTT GGTGGCAAAA AAACACAACG GGTATGTGCT 
CCAGAAGAAA CTACATTTCA CCTTCTACAC TTGTCTTTAA TGAGAGAGTA TATTGACTAT 
GAGTTTTCAG TATTAAAAGA AAAGATCACA TTTAAATATG ATATTGAAAG GATAATAGAT 
GATTGGATTT TGATGGGGTT TCTTGTTGGT AATGATTTTA TCCCTCATCT ACCTCATTTA 
CATATTAATC ATGATGCACT GCCTCTTCTT TATGGAACAT ATGTTACCAT CCTGCCAGAA 
CTTGGGGGTT ATATTAATGA AAGTGGGCAC CTCAACTTAC CTCGATTTGA GAAATACCTT 
GTGAAACTAT CAGATTTTGA TCGGGAGCAC TTCAGTGAAG TTTTTGTGGA CCTAAAATGG 
TTTGAAAGCA AAGTTGGTAA CAAGTACCTC AATGAAGCAG CAGGTGTCGC AGCAGAAGAA 
GCCAGGAACT ACAAGGAAAA GAAAAAGTTA AAGGGCCAGG AAAATTCTCT GTGTTGGACT 
GCTTTAGACA AAAATGAAGG CGAAATGATA ACTTCTAAGG ATAATTTAGA AGATGAGACT 
GAAGATGATG ACCTATTTGA AACTGAGTTT AGACAATATA AAAGAACATA TTACATGACG 
AAGATGGGGG TTGACGTAGT ATCTGATGAC TTTCTGGCTG ATCAAGCTGC ATGTTATGTT 
CAGGCAATAC AGTGGATTTT GCACTATTAC TATCATGGAG TTCAGTCCTG GAGCTGGTAT 
TATCCTTATC ATTATGCACC TTTCCTGTCT GATATACACA ACATCAGTAC ACTCAAAATC 
CATTTTGAAC TAGGAAAACC TTTTAAGCCA TTTGAACAGC TTCTTGCTGT ACTTCCAGCA 
GCCAGCAAAA ATTTACTTCC TGCATGCTAC CAGCATTTGA TGACCAATGA AGACTCACCA 
ATTATAGAAT ATTACCCACC TGATTTTAAA ACTGACCTAA ATGGGAAACA ACAGGAATGG 
GAAGCTGTGG TGTTAATCCC TTTTATTGAT GAGAAGCGAT TATTGGAAGC CATGGAGACA 
TGTAACCACT CCCTCAAAAA GGAAGAGAGG AAAAGAAACC AACATAGTGA GTGCCTAATG 
TGCTGGTATG ATAGAGACAC AGAGTTTATC TATCCTTCTC CATGGCCAGA AAAGTTCCCT 
GCCATAGAAC GATGTTGTAC AAGGTATAAA ATAATATCCT TAGATGCTTG GCGTGTAGAC 
ATAAACAAAA ACAAAATAAC CAGAATTGAC CAGAAAGCAT TATATTTCTG TGGATTTCCT 
ACTCTGAAAC ACATCAGACA CAAATTTTTT TTGAAGAAAA GTGGTGTTCA AGTATTCCAG 
CAAAGCAGTC GTGGAGAAAA CATGATGTTG GAAATCTTAG TGGATGCAGA ATCAGATGAA 
CTTACCGTAG AAAATGTAGC TTCATCAGTG CTTGGAAAAT CTGTCTTTGT TAATTGGCCT 
CACCTTGAGG AAGCTAGAGT CGTGGCTGTA TCAGATGGAG AAACTAAGTT TTACTTGGAA 
GAACCTCCAG GAACACAGAA GCTTTATTCA GGAAGAACTG CCCCACCATC TAAAGTGGTT 
CATCTTGGAG ATAAAGAACA ATCTAACTGG GCAAAAGAAG TACAAGGAAT TTCAGAACAC 
TACCTGAGAA GAAAAGGAAT AATAATAAAT GAAACATCTG CAGTTGTGTA TGCTCAGTTA 
CTCACAGGTC GTAAATATCA AATAAATCAA AATGGTGAAG TTCGTCTAGA GAAACAGTGG 
TCAAAACAAG TTGTTCCTTT TGTTTATCAA ACTATTGTCA AGGACATCCG AGCTTTCGAC 
TCCCGTTTCT CCAATATCAA AACATTGGAT GATTTGTTTC CTCTGAGAAG TATGGTCTTT 
ATGCTGGGAA CTCCCTATTA TGGCTGCACT GGAGAAGTTC AGGATTCAGG TGATGTGATT 
ACAGAAGGTA GGATTCGTGT GATTTTCAGC ATTCCATGTG AACCCAATCT TGATGCTTTA 
ATACAGAACC AGCATAAATA TTCTATAAAG TACAACCCAG GATATGTGTT GGCCAGTCGC 
CTTGGAGTGA GTGGATACCT TGTTTCAAGG TTTACAGGAA GTATTTTTAT TGGAAGAGGA 
TCTAGGAGAA ACCCTCATGG AGACCATAAA GCAAATGTGG GTTTAAATCT CAAATTCAAC 
AAGAAAAATG AGGAGGTACC TGGATATACT AAGAAAGTTG GAAGTGAATG GATGTATTCA 
TCTGCAGCAG AACAACTTCT GGCAGAGTAC TTAGAGAGAG CTCCAGAACT ATTTAGTTAT 
ATAGCCAAAA ATAGCCAAGA GGATGTGTTC TATGAAGATG ACATTTGGCC TGGAGAAAAT 
GAGAATGGTG CTGAAAAAGT TCAAGAAATT ATTACTTGGC TAAAAGGACA TCCTGTCAGT 
ACTTTATCTC GTTCTTCTTG TGATTTACAA ATTCTGGATG CAGCTATTGT TGAGAAAATT 
GAGGAAGAAG TCGAAAAGTG CAAGCAAAGA AAGAATAATA AGAAGGTGCG AGTAACAGTG 
AAACCCCATT TGCTATACAG ACCTTTAGAA CAGCAACATG GAGTCATTCC TGATCGGGAT 
GCAGAATTTT GTCTTTTTGA CCGTGTTGTA AATGTGAGAG AAAACTTCTC AGTTCCAGTT 
GGCCTTCGAG GCACCATCAT AGGAATAAAA GGAGCTAATA GAGAAGCCGA TGTACTATTT 
GAAGTATTAT TTGATGAAGA ATTTCCTGGA GGGTTAACAA TAAGATGCTC ACCTGGTAGA 
GGTTATCGAC TGCCAACAAG TGCCTTGGTG AACCTTTCTC ATGGGAGTCG CTCTGAAACT 
GGAAATCAGA AGTTGACAGC CATCGTAAAA CCACAACCAG CTGTACATCA ACATAGCTCA 
AGTTCATCAG TTTCCTCTGG GCATTTGGGA GCCCTCAACC ATTCCCCTCA ATCACTTTTT 
GTTCCTACTC AAGTACCTAC TAAAGATGAT GATGAATTCT GCAACATTTG GCAGTCCTTA 
CAGGGATCTG GAAAGATGCA ATACTTTCAG CCAACTATAC AAGAGAAGGG TGCAGTTCTA 
CCTCAAGAAA TAAGCCAAGT AAATCAACAT CATAAATCTG GCTTTAATGA CAACAGTGTT 
AAATATCAGC AAAGAAAACA TGACCCTCAC AGAAAATTTA AAGAAGAGTG TAAGAGTCCT 
AAAGCTGAGT GTTGGTCCCA AAAAATGTCC AATAAGCAGC CTAACTCTGG AATTGAGAAC 
TTTTTAGCAT CTTTGAATAT CTCCAAAGAA AATGAAGTAC AGTCATCTCA TCATGGGGAG 
CCTCCAAGTG AAGAGCATTT GTCACCACAG TCATTTGCCA TGAAGGGAAC ACGGATGCTT 
AAAGAAATTC TAAAAATTGA TGGCTCTAAC ACTGTGGACC ATAAGAATGA AATCAAACAG 
ATTGCTAATG AAATCCCTGT TTCCTCTAAC AGAAGAGATG AATATGGATT ACCCTCTCAG 
CCTAAACAAA ATAAGAAATT AGCATCTTAT ATGAACAAGC CTCACAGTGC TAATGAGTAC 
CATAATGTTC AGTCTATGGA CAATATGTGT TGGCCTGCCC CCAGCCAGAT CCCTCCTGTA 
TCCACACCAG TAACTGAACT TTCTCGAATT TGTTCCCTTG TTGGAATGCC ACAACCTGAT 
TTCTCCTTTC TTAGGATGCC ACAGACAATG ACCGTTTGCC AAGTAAAATT ATCTAATGGC 
TTACTGGTAC ATGGGCCACA GTGCCACTCT GAAAATGAAG CCAAAGAGAA AGCTGCACTT 
TTTGCTTTAC AACAGTTGGG CTCCTTAGGC ATGAATTTCC CTTTGCCTTC ACAAGTATTT 
GCAAATTATC CTTCAGCTGT ACCACCTGGA ACCATTCCTC CAGCCTTTCC CCCACCTACT 
GGCTGGGATC ACTATGGAAG CAACTATGCA TTGGGGGCAG CTAATATAAT GCCTTCGTCG 
TCTCATCTCT TTGGCTCAAT GCCATGGGGA CCATCGGTGC CAGTTCCTGG GAAGCCCTTC 
CATCATACTT TATATTCTGG GACCATGCCC ATGGCTGGGG GAATACCAGG GGGTGTGCAC 
AATCAGTTTA TACCTCTGCA GGTTACTAAA AAAAGGGTTG CAAACAAAAA GAACTTTGAG 
AATAAGGAAG CCCAGAGTTC TCAAGCCACT CCAGTTCAGA CTAGCCAGCC AGATTCTTCC 
AACATTGTCA AAGTAAGTCC ACGGGAGAGC TCATCAGCTT CTTTGAAGTC CTCTCCGATT 
GCTCAACCTG CATCTTCTTT TCAAGTTGAA ACTGCCTCTC AAGGCCATAG TATATCTCAC 
CATAAGTCAA CACCAATCTC TTCTTCAAGA AGAAAATCAA GAAAACTGGC TGTTAATTTT 
GGTGTTTCTA AACCTTCTGA GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

XRN1 ( XM_011512920.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011511222.1 Homo sapiens 5'-3' exoribonuclease 1 (XRN1), transcript variant X3, mRNA.

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CloneID	OHu68346
Clone ID Related Accession (Same CDS sequence)	XM_011512920.2
Accession Version	XM_011512920.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 5010bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	5'-3' exoribonuclease 1 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011512920.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGAGTCC CCAAGTTTTA CAGATGGATC TCAGAGCGGT ATCCCTGTCT CAGCGAAGTG 
GTGAAAGAGC ATCAGATTCC TGAATTTGAC AACTTGTACC TGGATATGAA TGGAATTATA 
CATCAGTGCT CCCATCCTAA TGATGATGAT GTTCACTTTA GAATTTCAGA TGATAAAATC 
TTTACTGATA TTTTTCACTA CCTGGAGGTG TTGTTTCGCA TTATTAAACC CAGGAAAGTG 
TTCTTTATGG CTGTAGATGG TGTGGCTCCT CGAGCAAAAA TGAACCAGCA GCGTGGGAGG 
CGTTTTAGGT CAGCAAAGGA GGCAGAAGAC AAAATTAAAA AGGCAATAGA GAAGGGAGAA 
ACTCTTCCTA CAGAGGCCAG ATTTGATTCC AACTGTATCA CACCAGGAAC TGAATTTATG 
GCCAGGTTAC ATGAACATCT GAAGTATTTT GTAAATATGA AAATTTCCAC AGACAAGTCA 
TGGCAAGGAG TTACCATCTA CTTCTCAGGC CATGAGACTC CTGGAGAAGG AGAGCATAAA 
ATCATGGAAT TTATCAGATC CGAGAAAGCA AAGCCAGATC ATGATCCAAA CACCAGACAC 
TGTCTTTATG GTTTAGATGC TGACTTGATT ATGCTTGGAT TAACAAGTCA TGAGGCACAT 
TTTTCTCTCT TAAGAGAAGA AGTTCGATTT GGTGGCAAAA AAACACAACG GGTATGTGCT 
CCAGAAGAAA CTACATTTCA CCTTCTACAC TTGTCTTTAA TGAGAGAGTA TATTGACTAT 
GAGTTTTCAG TATTAAAAGA AAAGATCACA TTTAAATATG ATATTGAAAG GATAATAGAT 
GATTGGATTT TGATGGGGTT TCTTGTTGGT AATGATTTTA TCCCTCATCT ACCTCATTTA 
CATATTAATC ATGATGCACT GCCTCTTCTT TATGGAACAT ATGTTACCAT CCTGCCAGAA 
CTTGGGGGTT ATATTAATGA AAGTGGGCAC CTCAACTTAC CTCGATTTGA GAAATACCTT 
GTGAAACTAT CAGATTTTGA TCGGGAGCAC TTCAGTGAAG TTTTTGTGGA CCTAAAATGG 
TTTGAAAGCA AAGTTGGTAA CAAGTACCTC AATGAAGCAG CAGGTGTCGC AGCAGAAGAA 
GCCAGGAACT ACAAGGAAAA GAAAAAGTTA AAGGGCCAGG AAAATTCTCT GTGTTGGACT 
GCTTTAGACA AAAATGAAGG CGAAATGATA ACTTCTAAGG ATAATTTAGA AGATGAGACT 
GAAGATGATG ACCTATTTGA AACTGAGTTT AGACAATATA AAAGAACATA TTACATGACG 
AAGATGGGGG TTGACGTAGT ATCTGATGAC TTTCTGGCTG ATCAAGCTGC ATGTTATGTT 
CAGGCAATAC AGTGGATTTT GCACTATTAC TATCATGGAG TTCAGTCCTG GAGCTGGTAT 
TATCCTTATC ATTATGCACC TTTCCTGTCT GATATACACA ACATCAGTAC ACTCAAAATC 
CATTTTGAAC TAGGAAAACC TTTTAAGCCA TTTGAACAGC TTCTTGCTGT ACTTCCAGCA 
GCCAGCAAAA ATTTACTTCC TGCATGCTAC CAGCATTTGA TGACCAATGA AGACTCACCA 
ATTATAGAAT ATTACCCACC TGATTTTAAA ACTGACCTAA ATGGGAAACA ACAGGAATGG 
GAAGCTGTGG TGTTAATCCC TTTTATTGAT GAGAAGCGAT TATTGGAAGC CATGGAGACA 
TGTAACCACT CCCTCAAAAA GGAAGAGAGG AAAAGAAACC AACATAGTGA GTGCCTAATG 
TGCTGGTATG ATAGAGACAC AGAGTTTATC TATCCTTCTC CATGGCCAGA AAAGTTCCCT 
GCCATAGAAC GATGTTGTAC AAGGTATAAA ATAATATCCT TAGATGCTTG GCGTGTAGAC 
ATAAACAAAA ACAAAATAAC CAGAATTGAC CAGAAAGCAT TATATTTCTG TGGATTTCCT 
ACTCTGAAAC ACATCAGACA CAAATTTTTT TTGAAGAAAA GTGGTGTTCA AGTATTCCAG 
CAAAGCAGTC GTGGAGAAAA CATGATGTTG GAAATCTTAG TGGATGCAGA ATCAGATGAA 
CTTACCGTAG AAAATGTAGC TTCATCAGTG CTTGGAAAAT CTGTCTTTGT TAATTGGCCT 
CACCTTGAGG AAGCTAGAGT CGTGGCTGTA TCAGATGGAG AAACTAAGTT TTACTTGGAA 
GAACCTCCAG GAACACAGAA GCTTTATTCA GGAAGAACTG CCCCACCATC TAAAGTGGTT 
CATCTTGGAG ATAAAGAACA ATCTAACTGG GCAAAAGAAG TACAAGGAAT TTCAGAACAC 
TACCTGAGAA GAAAAGGAAT AATAATAAAT GAAACATCTG CAGTTGTGTA TGCTCAGTTA 
CTCACAGGTC GTAAATATCA AATAAATCAA AATGGTGAAG TTCGTCTAGA GAAACAGTGG 
TCAAAACAAG TTGTTCCTTT TGTTTATCAA ACTATTGTCA AGGACATCCG AGCTTTCGAC 
TCCCGTTTCT CCAATATCAA AACATTGGAT GATTTGTTTC CTCTGAGAAG TATGGTCTTT 
ATGCTGGGAA CTCCCTATTA TGGCTGCACT GGAGAAGTTC AGGATTCAGG TGATGTGATT 
ACAGAAGGTA GGATTCGTGT GATTTTCAGC ATTCCATGTG AACCCAATCT TGATGCTTTA 
ATACAGAACC AGCATAAATA TTCTATAAAG TACAACCCAG GATATGTGTT GGCCAGTCGC 
CTTGGAGTGA GTGGATACCT TGTTTCAAGG TTTACAGGAA GTATTTTTAT TGGAAGAGGA 
TCTAGGAGAA ACCCTCATGG AGACCATAAA GCAAATGTGG GTTTAAATCT CAAATTCAAC 
AAGAAAAATG AGGAGGTACC TGGATATACT AAGAAAGTTG GAAGTGAATG GATGTATTCA 
TCTGCAGCAG AACAACTTCT GGCAGAGTAC TTAGAGAGAG CTCCAGAACT ATTTAGTTAT 
ATAGCCAAAA ATAGCCAAGA GGATGTGTTC TATGAAGATG ACATTTGGCC TGGAGAAAAT 
GAGAATGGTG CTGAAAAAGT TCAAGAAATT ATTACTTGGC TAAAAGGACA TCCTGTCAGT 
ACTTTATCTC GTTCTTCTTG TGATTTACAA ATTCTGGATG CAGCTATTGT TGAGAAAATT 
GAGGAAGAAG TCGAAAAGTG CAAGCAAAGA AAGAATAATA AGAAGGTGCG AGTAACAGTG 
AAACCCCATT TGCTATACAG ACCTTTAGAA CAGCAACATG GAGTCATTCC TGATCGGGAT 
GCAGAATTTT GTCTTTTTGA CCGTGTTGTA AATGTGAGAG AAAACTTCTC AGTTCCAGTT 
GGCCTTCGAG GCACCATCAT AGGAATAAAA GGAGCTAATA GAGAAGCCGA TGTACTATTT 
GAAGTATTAT TTGATGAAGA ATTTCCTGGA GGGTTAACAA TAAGATGCTC ACCTGGTAGA 
GGTTATCGAC TGCCAACAAG TGCCTTGGTG AACCTTTCTC ATGGGAGTCG CTCTGAAACT 
GGAAATCAGA AGTTGACAGC CATCGTAAAA CCACAACCAG CTGTACATCA ACATAGCTCA 
AGTTCATCAG TTTCCTCTGG GCATTTGGGA GCCCTCAACC ATTCCCCTCA ATCACTTTTT 
GTTCCTACTC AAGTACCTAC TAAAGATGAT GATGAATTCT GCAACATTTG GCAGTCCTTA 
CAGGGATCTG GAAAGATGCA ATACTTTCAG CCAACTATAC AAGAGAAGGG TGCAGTTCTA 
CCTCAAGAAA TAAGCCAAGT AAATCAACAT CATAAATCTG GCTTTAATGA CAACAGTGTT 
AAATATCAGC AAAGAAAACA TGACCCTCAC AGAAAATTTA AAGAAGAGTG TAAGAGTCCT 
AAAGCTGAGT GTTGGTCCCA AAAAATGTCC AATAAGCAGC CTAACTCTGG AATTGAGAAC 
TTTTTAGCAT CTTTGAATAT CTCCAAAGAA AATGAAGTAC AGTCATCTCA TCATGGGGAG 
CCTCCAAGTG AAGAGCATTT GTCACCACAG TCATTTGCCA TGAAGGGAAC ACGGATGCTT 
AAAGAAATTC TAAAAATTGA TGGCTCTAAC ACTGTGGACC ATAAGAATGA AATCAAACAG 
ATTGCTAATG AAATCCCTGT TTCCTCTAAC AGAAGAGATG AATATGGATT ACCCTCTCAG 
CCTAAACAAA ATAAGAAATT AGCATCTTAT ATGAACAAGC CTCACAGTGC TAATGAGTAC 
CATAATGTTC AGTCTATGGA CAATATGTGT TGGCCTGCCC CCAGCCAGAT CCCTCCTGTA 
TCCACACCAG TAACTGAACT TTCTCGAATT TGTTCCCTTG TTGGAATGCC ACAACCTGAT 
TTCTCCTTTC TTAGGATGCC ACAGGGCTCC TTAGGCATGA ATTTCCCTTT GCCTTCACAA 
GTATTTGCAA ATTATCCTTC AGCTGTACCA CCTGGAACCA TTCCTCCAGC CTTTCCCCCA 
CCTACTGGCT GGGATCACTA TGGAAGCAAC TATGCATTGG GGGCAGCTAA TATAATGCCT 
TCGTCGTCTC ATCTCTTTGG CTCAATGCCA TGGGGACCAT CGGTGCCAGT TCCTGGGAAG 
CCCTTCCATC ATACTTTATA TTCTGGGACC ATGCCCATGG CTGGGGGAAT ACCAGGGGGT 
GTGCACAATC AGTTTATACC TCTGCAGGTT ACTAAAAAAA GGGTTGCAAA CAAAAAGAAC 
TTTGAGAATA AGGAAGCCCA GAGTTCTCAA GCCACTCCAG TTCAGACTAG CCAGCCAGAT 
TCTTCCAACA TTGTCAAAGT AAGTCCACGG GAGAGCTCAT CAGCTTCTTT GAAGTCCTCT 
CCGATTGCTC AACCTGCATC TTCTTTTCAA GTTGAAACTG CCTCTCAAGG CCATAGTATA 
TCTCACCATA AGTCAACACC AATCTCTTCT TCAAGAAGAA AATCAAGAAA ACTGGCTGTT 
AATTTTGGTG TTTCTAAACC TTCTGAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011511222.1
CDS	119..5128
Translation	MGVPKFYRWISERYPCLSEVVKEHQIPEFDNLYLDMNGIIHQCSHPNDDDVHFRISDDKIFTDIFHYLEVLFRIIKPRKVFFMAVDGVAPRAKMNQQRGRRFRSAKEAEDKIKKAIEKGETLPTEARFDSNCITPGTEFMARLHEHLKYFVNMKISTDKSWQGVTIYFSGHETPGEGEHKIMEFIRSEKAKPDHDPNTRHCLYGLDADLIMLGLTSHEAHFSLLREEVRFGGKKTQRVCAPEETTFHLLHLSLMREYIDYEFSVLKEKITFKYDIERIIDDWILMGFLVGNDFIPHLPHLHINHDALPLLYGTYVTILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKWFESKVGNKYLNEAAGVAAEEARNYKEKKKLKGQENSLCWTALDKNEGEMITSKDNLEDETEDDDLFETEFRQYKRTYYMTKMGVDVVSDDFLADQAACYVQAIQWILHYYYHGVQSWSWYYPYHYAPFLSDIHNISTLKIHFELGKPFKPFEQLLAVLPAASKNLLPACYQHLMTNEDSPIIEYYPPDFKTDLNGKQQEWEAVVLIPFIDEKRLLEAMETCNHSLKKEERKRNQHSECLMCWYDRDTEFIYPSPWPEKFPAIERCCTRYKIISLDAWRVDINKNKITRIDQKALYFCGFPTLKHIRHKFFLKKSGVQVFQQSSRGENMMLEILVDAESDELTVENVASSVLGKSVFVNWPHLEEARVVAVSDGETKFYLEEPPGTQKLYSGRTAPPSKVVHLGDKEQSNWAKEVQGISEHYLRRKGIIINETSAVVYAQLLTGRKYQINQNGEVRLEKQWSKQVVPFVYQTIVKDIRAFDSRFSNIKTLDDLFPLRSMVFMLGTPYYGCTGEVQDSGDVITEGRIRVIFSIPCEPNLDALIQNQHKYSIKYNPGYVLASRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFNKKNEEVPGYTKKVGSEWMYSSAAEQLLAEYLERAPELFSYIAKNSQEDVFYEDDIWPGENENGAEKVQEIITWLKGHPVSTLSRSSCDLQILDAAIVEKIEEEVEKCKQRKNNKKVRVTVKPHLLYRPLEQQHGVIPDRDAEFCLFDRVVNVRENFSVPVGLRGTIIGIKGANREADVLFEVLFDEEFPGGLTIRCSPGRGYRLPTSALVNLSHGSRSETGNQKLTAIVKPQPAVHQHSSSSSVSSGHLGALNHSPQSLFVPTQVPTKDDDEFCNIWQSLQGSGKMQYFQPTIQEKGAVLPQEISQVNQHHKSGFNDNSVKYQQRKHDPHRKFKEECKSPKAECWSQKMSNKQPNSGIENFLASLNISKENEVQSSHHGEPPSEEHLSPQSFAMKGTRMLKEILKIDGSNTVDHKNEIKQIANEIPVSSNRRDEYGLPSQPKQNKKLASYMNKPHSANEYHNVQSMDNMCWPAPSQIPPVSTPVTELSRICSLVGMPQPDFSFLRMPQGSLGMNFPLPSQVFANYPSAVPPGTIPPAFPPPTGWDHYGSNYALGAANIMPSSSHLFGSMPWGPSVPVPGKPFHHTLYSGTMPMAGGIPGGVHNQFIPLQVTKKRVANKKNFENKEAQSSQATPVQTSQPDSSNIVKVSPRESSSASLKSSPIAQPASSFQVETASQGHSISHHKSTPISSSRRKSRKLAVNFGVSKPSE

Target ORF information:

RefSeq Version	XM_011512920.2
Organism	Homo sapiens(human)
Definition	Homo sapiens 5'-3' exoribonuclease 1 (XRN1), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011512920.2

ORF Insert Sequence:

ATGGGAGTCC CCAAGTTTTA CAGATGGATC TCAGAGCGGT ATCCCTGTCT CAGCGAAGTG 
GTGAAAGAGC ATCAGATTCC TGAATTTGAC AACTTGTACC TGGATATGAA TGGAATTATA 
CATCAGTGCT CCCATCCTAA TGATGATGAT GTTCACTTTA GAATTTCAGA TGATAAAATC 
TTTACTGATA TTTTTCACTA CCTGGAGGTG TTGTTTCGCA TTATTAAACC CAGGAAAGTG 
TTCTTTATGG CTGTAGATGG TGTGGCTCCT CGAGCAAAAA TGAACCAGCA GCGTGGGAGG 
CGTTTTAGGT CAGCAAAGGA GGCAGAAGAC AAAATTAAAA AGGCAATAGA GAAGGGAGAA 
ACTCTTCCTA CAGAGGCCAG ATTTGATTCC AACTGTATCA CACCAGGAAC TGAATTTATG 
GCCAGGTTAC ATGAACATCT GAAGTATTTT GTAAATATGA AAATTTCCAC AGACAAGTCA 
TGGCAAGGAG TTACCATCTA CTTCTCAGGC CATGAGACTC CTGGAGAAGG AGAGCATAAA 
ATCATGGAAT TTATCAGATC CGAGAAAGCA AAGCCAGATC ATGATCCAAA CACCAGACAC 
TGTCTTTATG GTTTAGATGC TGACTTGATT ATGCTTGGAT TAACAAGTCA TGAGGCACAT 
TTTTCTCTCT TAAGAGAAGA AGTTCGATTT GGTGGCAAAA AAACACAACG GGTATGTGCT 
CCAGAAGAAA CTACATTTCA CCTTCTACAC TTGTCTTTAA TGAGAGAGTA TATTGACTAT 
GAGTTTTCAG TATTAAAAGA AAAGATCACA TTTAAATATG ATATTGAAAG GATAATAGAT 
GATTGGATTT TGATGGGGTT TCTTGTTGGT AATGATTTTA TCCCTCATCT ACCTCATTTA 
CATATTAATC ATGATGCACT GCCTCTTCTT TATGGAACAT ATGTTACCAT CCTGCCAGAA 
CTTGGGGGTT ATATTAATGA AAGTGGGCAC CTCAACTTAC CTCGATTTGA GAAATACCTT 
GTGAAACTAT CAGATTTTGA TCGGGAGCAC TTCAGTGAAG TTTTTGTGGA CCTAAAATGG 
TTTGAAAGCA AAGTTGGTAA CAAGTACCTC AATGAAGCAG CAGGTGTCGC AGCAGAAGAA 
GCCAGGAACT ACAAGGAAAA GAAAAAGTTA AAGGGCCAGG AAAATTCTCT GTGTTGGACT 
GCTTTAGACA AAAATGAAGG CGAAATGATA ACTTCTAAGG ATAATTTAGA AGATGAGACT 
GAAGATGATG ACCTATTTGA AACTGAGTTT AGACAATATA AAAGAACATA TTACATGACG 
AAGATGGGGG TTGACGTAGT ATCTGATGAC TTTCTGGCTG ATCAAGCTGC ATGTTATGTT 
CAGGCAATAC AGTGGATTTT GCACTATTAC TATCATGGAG TTCAGTCCTG GAGCTGGTAT 
TATCCTTATC ATTATGCACC TTTCCTGTCT GATATACACA ACATCAGTAC ACTCAAAATC 
CATTTTGAAC TAGGAAAACC TTTTAAGCCA TTTGAACAGC TTCTTGCTGT ACTTCCAGCA 
GCCAGCAAAA ATTTACTTCC TGCATGCTAC CAGCATTTGA TGACCAATGA AGACTCACCA 
ATTATAGAAT ATTACCCACC TGATTTTAAA ACTGACCTAA ATGGGAAACA ACAGGAATGG 
GAAGCTGTGG TGTTAATCCC TTTTATTGAT GAGAAGCGAT TATTGGAAGC CATGGAGACA 
TGTAACCACT CCCTCAAAAA GGAAGAGAGG AAAAGAAACC AACATAGTGA GTGCCTAATG 
TGCTGGTATG ATAGAGACAC AGAGTTTATC TATCCTTCTC CATGGCCAGA AAAGTTCCCT 
GCCATAGAAC GATGTTGTAC AAGGTATAAA ATAATATCCT TAGATGCTTG GCGTGTAGAC 
ATAAACAAAA ACAAAATAAC CAGAATTGAC CAGAAAGCAT TATATTTCTG TGGATTTCCT 
ACTCTGAAAC ACATCAGACA CAAATTTTTT TTGAAGAAAA GTGGTGTTCA AGTATTCCAG 
CAAAGCAGTC GTGGAGAAAA CATGATGTTG GAAATCTTAG TGGATGCAGA ATCAGATGAA 
CTTACCGTAG AAAATGTAGC TTCATCAGTG CTTGGAAAAT CTGTCTTTGT TAATTGGCCT 
CACCTTGAGG AAGCTAGAGT CGTGGCTGTA TCAGATGGAG AAACTAAGTT TTACTTGGAA 
GAACCTCCAG GAACACAGAA GCTTTATTCA GGAAGAACTG CCCCACCATC TAAAGTGGTT 
CATCTTGGAG ATAAAGAACA ATCTAACTGG GCAAAAGAAG TACAAGGAAT TTCAGAACAC 
TACCTGAGAA GAAAAGGAAT AATAATAAAT GAAACATCTG CAGTTGTGTA TGCTCAGTTA 
CTCACAGGTC GTAAATATCA AATAAATCAA AATGGTGAAG TTCGTCTAGA GAAACAGTGG 
TCAAAACAAG TTGTTCCTTT TGTTTATCAA ACTATTGTCA AGGACATCCG AGCTTTCGAC 
TCCCGTTTCT CCAATATCAA AACATTGGAT GATTTGTTTC CTCTGAGAAG TATGGTCTTT 
ATGCTGGGAA CTCCCTATTA TGGCTGCACT GGAGAAGTTC AGGATTCAGG TGATGTGATT 
ACAGAAGGTA GGATTCGTGT GATTTTCAGC ATTCCATGTG AACCCAATCT TGATGCTTTA 
ATACAGAACC AGCATAAATA TTCTATAAAG TACAACCCAG GATATGTGTT GGCCAGTCGC 
CTTGGAGTGA GTGGATACCT TGTTTCAAGG TTTACAGGAA GTATTTTTAT TGGAAGAGGA 
TCTAGGAGAA ACCCTCATGG AGACCATAAA GCAAATGTGG GTTTAAATCT CAAATTCAAC 
AAGAAAAATG AGGAGGTACC TGGATATACT AAGAAAGTTG GAAGTGAATG GATGTATTCA 
TCTGCAGCAG AACAACTTCT GGCAGAGTAC TTAGAGAGAG CTCCAGAACT ATTTAGTTAT 
ATAGCCAAAA ATAGCCAAGA GGATGTGTTC TATGAAGATG ACATTTGGCC TGGAGAAAAT 
GAGAATGGTG CTGAAAAAGT TCAAGAAATT ATTACTTGGC TAAAAGGACA TCCTGTCAGT 
ACTTTATCTC GTTCTTCTTG TGATTTACAA ATTCTGGATG CAGCTATTGT TGAGAAAATT 
GAGGAAGAAG TCGAAAAGTG CAAGCAAAGA AAGAATAATA AGAAGGTGCG AGTAACAGTG 
AAACCCCATT TGCTATACAG ACCTTTAGAA CAGCAACATG GAGTCATTCC TGATCGGGAT 
GCAGAATTTT GTCTTTTTGA CCGTGTTGTA AATGTGAGAG AAAACTTCTC AGTTCCAGTT 
GGCCTTCGAG GCACCATCAT AGGAATAAAA GGAGCTAATA GAGAAGCCGA TGTACTATTT 
GAAGTATTAT TTGATGAAGA ATTTCCTGGA GGGTTAACAA TAAGATGCTC ACCTGGTAGA 
GGTTATCGAC TGCCAACAAG TGCCTTGGTG AACCTTTCTC ATGGGAGTCG CTCTGAAACT 
GGAAATCAGA AGTTGACAGC CATCGTAAAA CCACAACCAG CTGTACATCA ACATAGCTCA 
AGTTCATCAG TTTCCTCTGG GCATTTGGGA GCCCTCAACC ATTCCCCTCA ATCACTTTTT 
GTTCCTACTC AAGTACCTAC TAAAGATGAT GATGAATTCT GCAACATTTG GCAGTCCTTA 
CAGGGATCTG GAAAGATGCA ATACTTTCAG CCAACTATAC AAGAGAAGGG TGCAGTTCTA 
CCTCAAGAAA TAAGCCAAGT AAATCAACAT CATAAATCTG GCTTTAATGA CAACAGTGTT 
AAATATCAGC AAAGAAAACA TGACCCTCAC AGAAAATTTA AAGAAGAGTG TAAGAGTCCT 
AAAGCTGAGT GTTGGTCCCA AAAAATGTCC AATAAGCAGC CTAACTCTGG AATTGAGAAC 
TTTTTAGCAT CTTTGAATAT CTCCAAAGAA AATGAAGTAC AGTCATCTCA TCATGGGGAG 
CCTCCAAGTG AAGAGCATTT GTCACCACAG TCATTTGCCA TGAAGGGAAC ACGGATGCTT 
AAAGAAATTC TAAAAATTGA TGGCTCTAAC ACTGTGGACC ATAAGAATGA AATCAAACAG 
ATTGCTAATG AAATCCCTGT TTCCTCTAAC AGAAGAGATG AATATGGATT ACCCTCTCAG 
CCTAAACAAA ATAAGAAATT AGCATCTTAT ATGAACAAGC CTCACAGTGC TAATGAGTAC 
CATAATGTTC AGTCTATGGA CAATATGTGT TGGCCTGCCC CCAGCCAGAT CCCTCCTGTA 
TCCACACCAG TAACTGAACT TTCTCGAATT TGTTCCCTTG TTGGAATGCC ACAACCTGAT 
TTCTCCTTTC TTAGGATGCC ACAGGGCTCC TTAGGCATGA ATTTCCCTTT GCCTTCACAA 
GTATTTGCAA ATTATCCTTC AGCTGTACCA CCTGGAACCA TTCCTCCAGC CTTTCCCCCA 
CCTACTGGCT GGGATCACTA TGGAAGCAAC TATGCATTGG GGGCAGCTAA TATAATGCCT 
TCGTCGTCTC ATCTCTTTGG CTCAATGCCA TGGGGACCAT CGGTGCCAGT TCCTGGGAAG 
CCCTTCCATC ATACTTTATA TTCTGGGACC ATGCCCATGG CTGGGGGAAT ACCAGGGGGT 
GTGCACAATC AGTTTATACC TCTGCAGGTT ACTAAAAAAA GGGTTGCAAA CAAAAAGAAC 
TTTGAGAATA AGGAAGCCCA GAGTTCTCAA GCCACTCCAG TTCAGACTAG CCAGCCAGAT 
TCTTCCAACA TTGTCAAAGT AAGTCCACGG GAGAGCTCAT CAGCTTCTTT GAAGTCCTCT 
CCGATTGCTC AACCTGCATC TTCTTTTCAA GTTGAAACTG CCTCTCAAGG CCATAGTATA 
TCTCACCATA AGTCAACACC AATCTCTTCT TCAAGAAGAA AATCAAGAAA ACTGGCTGTT 
AATTTTGGTG TTTCTAAACC TTCTGAGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

XRN1 ( XM_011512922.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011511224.1 Homo sapiens 5'-3' exoribonuclease 1 (XRN1), transcript variant X5, mRNA.

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CloneID	OHu68348
Clone ID Related Accession (Same CDS sequence)	XM_011512922.2
Accession Version	XM_011512922.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4494bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	5'-3' exoribonuclease 1 isoform X5
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011512922.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTTGGAT TAACAAGTCA TGAGGCACAT TTTTCTCTCT TAAGAGAAGA AGTTCGATTT 
GGTGGCAAAA AAACACAACG GGTATGTGCT CCAGAAGAAA CTACATTTCA CCTTCTACAC 
TTGTCTTTAA TGAGAGAGTA TATTGACTAT GAGTTTTCAG TATTAAAAGA AAAGATCACA 
TTTAAATATG ATATTGAAAG GATAATAGAT GATTGGATTT TGATGGGGTT TCTTGTTGGT 
AATGATTTTA TCCCTCATCT ACCTCATTTA CATATTAATC ATGATGCACT GCCTCTTCTT 
TATGGAACAT ATGTTACCAT CCTGCCAGAA CTTGGGGGTT ATATTAATGA AAGTGGGCAC 
CTCAACTTAC CTCGATTTGA GAAATACCTT GTGAAACTAT CAGATTTTGA TCGGGAGCAC 
TTCAGTGAAG TTTTTGTGGA CCTAAAATGG TTTGAAAGCA AAGTTGGTAA CAAGTACCTC 
AATGAAGCAG CAGGTGTCGC AGCAGAAGAA GCCAGGAACT ACAAGGAAAA GAAAAAGTTA 
AAGGGCCAGG AAAATTCTCT GTGTTGGACT GCTTTAGACA AAAATGAAGG CGAAATGATA 
ACTTCTAAGG ATAATTTAGA AGATGAGACT GAAGATGATG ACCTATTTGA AACTGAGTTT 
AGACAATATA AAAGAACATA TTACATGACG AAGATGGGGG TTGACGTAGT ATCTGATGAC 
TTTCTGGCTG ATCAAGCTGC ATGTTATGTT CAGGCAATAC AGTGGATTTT GCACTATTAC 
TATCATGGAG TTCAGTCCTG GAGCTGGTAT TATCCTTATC ATTATGCACC TTTCCTGTCT 
GATATACACA ACATCAGTAC ACTCAAAATC CATTTTGAAC TAGGAAAACC TTTTAAGCCA 
TTTGAACAGC TTCTTGCTGT ACTTCCAGCA GCCAGCAAAA ATTTACTTCC TGCATGCTAC 
CAGCATTTGA TGACCAATGA AGACTCACCA ATTATAGAAT ATTACCCACC TGATTTTAAA 
ACTGACCTAA ATGGGAAACA ACAGGAATGG GAAGCTGTGG TGTTAATCCC TTTTATTGAT 
GAGAAGCGAT TATTGGAAGC CATGGAGACA TGTAACCACT CCCTCAAAAA GGAAGAGAGG 
AAAAGAAACC AACATAGTGA GTGCCTAATG TGCTGGTATG ATAGAGACAC AGAGTTTATC 
TATCCTTCTC CATGGCCAGA AAAGTTCCCT GCCATAGAAC GATGTTGTAC AAGGTATAAA 
ATAATATCCT TAGATGCTTG GCGTGTAGAC ATAAACAAAA ACAAAATAAC CAGAATTGAC 
CAGAAAGCAT TATATTTCTG TGGATTTCCT ACTCTGAAAC ACATCAGACA CAAATTTTTT 
TTGAAGAAAA GTGGTGTTCA AGTATTCCAG CAAAGCAGTC GTGGAGAAAA CATGATGTTG 
GAAATCTTAG TGGATGCAGA ATCAGATGAA CTTACCGTAG AAAATGTAGC TTCATCAGTG 
CTTGGAAAAT CTGTCTTTGT TAATTGGCCT CACCTTGAGG AAGCTAGAGT CGTGGCTGTA 
TCAGATGGAG AAACTAAGTT TTACTTGGAA GAACCTCCAG GAACACAGAA GCTTTATTCA 
GGAAGAACTG CCCCACCATC TAAAGTGGTT CATCTTGGAG ATAAAGAACA ATCTAACTGG 
GCAAAAGAAG TACAAGGAAT TTCAGAACAC TACCTGAGAA GAAAAGGAAT AATAATAAAT 
GAAACATCTG CAGTTGTGTA TGCTCAGTTA CTCACAGGTC GTAAATATCA AATAAATCAA 
AATGGTGAAG TTCGTCTAGA GAAACAGTGG TCAAAACAAG TTGTTCCTTT TGTTTATCAA 
ACTATTGTCA AGGACATCCG AGCTTTCGAC TCCCGTTTCT CCAATATCAA AACATTGGAT 
GATTTGTTTC CTCTGAGAAG TATGGTCTTT ATGCTGGGAA CTCCCTATTA TGGCTGCACT 
GGAGAAGTTC AGGATTCAGG TGATGTGATT ACAGAAGGTA GGATTCGTGT GATTTTCAGC 
ATTCCATGTG AACCCAATCT TGATGCTTTA ATACAGAACC AGCATAAATA TTCTATAAAG 
TACAACCCAG GATATGTGTT GGCCAGTCGC CTTGGAGTGA GTGGATACCT TGTTTCAAGG 
TTTACAGGAA GTATTTTTAT TGGAAGAGGA TCTAGGAGAA ACCCTCATGG AGACCATAAA 
GCAAATGTGG GTTTAAATCT CAAATTCAAC AAGAAAAATG AGGAGGTACC TGGATATACT 
AAGAAAGTTG GAAGTGAATG GATGTATTCA TCTGCAGCAG AACAACTTCT GGCAGAGTAC 
TTAGAGAGAG CTCCAGAACT ATTTAGTTAT ATAGCCAAAA ATAGCCAAGA GGATGTGTTC 
TATGAAGATG ACATTTGGCC TGGAGAAAAT GAGAATGGTG CTGAAAAAGT TCAAGAAATT 
ATTACTTGGC TAAAAGGACA TCCTGTCAGT ACTTTATCTC GTTCTTCTTG TGATTTACAA 
ATTCTGGATG CAGCTATTGT TGAGAAAATT GAGGAAGAAG TCGAAAAGTG CAAGCAAAGA 
AAGAATAATA AGAAGGTGCG AGTAACAGTG AAACCCCATT TGCTATACAG ACCTTTAGAA 
CAGCAACATG GAGTCATTCC TGATCGGGAT GCAGAATTTT GTCTTTTTGA CCGTGTTGTA 
AATGTGAGAG AAAACTTCTC AGTTCCAGTT GGCCTTCGAG GCACCATCAT AGGAATAAAA 
GGAGCTAATA GAGAAGCCGA TGTACTATTT GAAGTATTAT TTGATGAAGA ATTTCCTGGA 
GGGTTAACAA TAAGATGCTC ACCTGGTAGA GGTTATCGAC TGCCAACAAG TGCCTTGGTG 
AACCTTTCTC ATGGGAGTCG CTCTGAAACT GGAAATCAGA AGTTGACAGC CATCGTAAAA 
CCACAACCAG CTGTACATCA ACATAGCTCA AGTTCATCAG TTTCCTCTGG GCATTTGGGA 
GCCCTCAACC ATTCCCCTCA ATCACTTTTT GTTCCTACTC AAGTACCTAC TAAAGATGAT 
GATGAATTCT GCAACATTTG GCAGTCCTTA CAGGGATCTG GAAAGATGCA ATACTTTCAG 
CCAACTATAC AAGAGAAGGG TGCAGTTCTA CCTCAAGAAA TAAGCCAAGT AAATCAACAT 
CATAAATCTG GCTTTAATGA CAACAGTGTT AAATATCAGC AAAGAAAACA TGACCCTCAC 
AGAAAATTTA AAGAAGAGTG TAAGAGTCCT AAAGCTGAGT GTTGGTCCCA AAAAATGTCC 
AATAAGCAGC CTAACTCTGG AATTGAGAAC TTTTTAGCAT CTTTGAATAT CTCCAAAGAA 
AATGAAGTAC AGTCATCTCA TCATGGGGAG CCTCCAAGTG AAGAGCATTT GTCACCACAG 
TCATTTGCCA TGAAGGGAAC ACGGATGCTT AAAGAAATTC TAAAAATTGA TGGCTCTAAC 
ACTGTGGACC ATAAGAATGA AATCAAACAG ATTGCTAATG AAATCCCTGT TTCCTCTAAC 
AGAAGAGATG AATATGGATT ACCCTCTCAG CCTAAACAAA ATAAGAAATT AGCATCTTAT 
ATGAACAAGC CTCACAGTGC TAATGAGTAC CATAATGTTC AGTCTATGGA CAATATGTGT 
TGGCCTGCCC CCAGCCAGAT CCCTCCTGTA TCCACACCAG TAACTGAACT TTCTCGAATT 
TGTTCCCTTG TTGGAATGCC ACAACCTGAT TTCTCCTTTC TTAGGATGCC ACAGACAATG 
ACCGTTTGCC AAGTAAAATT ATCTAATGGC TTACTGGTAC ATGGGCCACA GTGCCACTCT 
GAAAATGAAG CCAAAGAGAA AGCTGCACTT TTTGCTTTAC AACAGTTGGG CTCCTTAGGC 
ATGAATTTCC CTTTGCCTTC ACAAGTATTT GCAAATTATC CTTCAGCTGT ACCACCTGGA 
ACCATTCCTC CAGCCTTTCC CCCACCTACT GGCTGGGATC ACTATGGAAG CAACTATGCA 
TTGGGGGCAG CTAATATAAT GCCTTCGTCG TCTCATCTCT TTGGCTCAAT GCCATGGGGA 
CCATCGGTGC CAGTTCCTGG GAAGCCCTTC CATCATACTT TATATTCTGG GACCATGCCC 
ATGGCTGGGG GAATACCAGG GGGTGTGCAC AATCAGTTTA TACCTCTGCA GGTTACTAAA 
AAAAGGGTTG CAAACAAAAA GAACTTTGAG AATAAGGAAG CCCAGAGTTC TCAAGCCACT 
CCAGTTCAGA CTAGCCAGCC AGATTCTTCC AACATTGTCA AAGTAAGTCC ACGGGAGAGC 
TCATCAGCTT CTTTGAAGTC CTCTCCGATT GCTCAACCTG CATCTTCTTT TCAAGTTGAA 
ACTGCCTCTC AAGGCCATAG TATATCTCAC CATAAGTCAA CACCAATCTC TTCTTCAAGA 
AGAAAATCAA GAAAACTGGC TGTTAATTTT GGTGTTTCTA AACCTTCTGA GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011511224.1
CDS	380..4873
Translation	MLGLTSHEAHFSLLREEVRFGGKKTQRVCAPEETTFHLLHLSLMREYIDYEFSVLKEKITFKYDIERIIDDWILMGFLVGNDFIPHLPHLHINHDALPLLYGTYVTILPELGGYINESGHLNLPRFEKYLVKLSDFDREHFSEVFVDLKWFESKVGNKYLNEAAGVAAEEARNYKEKKKLKGQENSLCWTALDKNEGEMITSKDNLEDETEDDDLFETEFRQYKRTYYMTKMGVDVVSDDFLADQAACYVQAIQWILHYYYHGVQSWSWYYPYHYAPFLSDIHNISTLKIHFELGKPFKPFEQLLAVLPAASKNLLPACYQHLMTNEDSPIIEYYPPDFKTDLNGKQQEWEAVVLIPFIDEKRLLEAMETCNHSLKKEERKRNQHSECLMCWYDRDTEFIYPSPWPEKFPAIERCCTRYKIISLDAWRVDINKNKITRIDQKALYFCGFPTLKHIRHKFFLKKSGVQVFQQSSRGENMMLEILVDAESDELTVENVASSVLGKSVFVNWPHLEEARVVAVSDGETKFYLEEPPGTQKLYSGRTAPPSKVVHLGDKEQSNWAKEVQGISEHYLRRKGIIINETSAVVYAQLLTGRKYQINQNGEVRLEKQWSKQVVPFVYQTIVKDIRAFDSRFSNIKTLDDLFPLRSMVFMLGTPYYGCTGEVQDSGDVITEGRIRVIFSIPCEPNLDALIQNQHKYSIKYNPGYVLASRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFNKKNEEVPGYTKKVGSEWMYSSAAEQLLAEYLERAPELFSYIAKNSQEDVFYEDDIWPGENENGAEKVQEIITWLKGHPVSTLSRSSCDLQILDAAIVEKIEEEVEKCKQRKNNKKVRVTVKPHLLYRPLEQQHGVIPDRDAEFCLFDRVVNVRENFSVPVGLRGTIIGIKGANREADVLFEVLFDEEFPGGLTIRCSPGRGYRLPTSALVNLSHGSRSETGNQKLTAIVKPQPAVHQHSSSSSVSSGHLGALNHSPQSLFVPTQVPTKDDDEFCNIWQSLQGSGKMQYFQPTIQEKGAVLPQEISQVNQHHKSGFNDNSVKYQQRKHDPHRKFKEECKSPKAECWSQKMSNKQPNSGIENFLASLNISKENEVQSSHHGEPPSEEHLSPQSFAMKGTRMLKEILKIDGSNTVDHKNEIKQIANEIPVSSNRRDEYGLPSQPKQNKKLASYMNKPHSANEYHNVQSMDNMCWPAPSQIPPVSTPVTELSRICSLVGMPQPDFSFLRMPQTMTVCQVKLSNGLLVHGPQCHSENEAKEKAALFALQQLGSLGMNFPLPSQVFANYPSAVPPGTIPPAFPPPTGWDHYGSNYALGAANIMPSSSHLFGSMPWGPSVPVPGKPFHHTLYSGTMPMAGGIPGGVHNQFIPLQVTKKRVANKKNFENKEAQSSQATPVQTSQPDSSNIVKVSPRESSSASLKSSPIAQPASSFQVETASQGHSISHHKSTPISSSRRKSRKLAVNFGVSKPSE

Target ORF information:

RefSeq Version	XM_011512922.2
Organism	Homo sapiens(human)
Definition	Homo sapiens 5'-3' exoribonuclease 1 (XRN1), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011512922.2

ORF Insert Sequence:

ATGCTTGGAT TAACAAGTCA TGAGGCACAT TTTTCTCTCT TAAGAGAAGA AGTTCGATTT 
GGTGGCAAAA AAACACAACG GGTATGTGCT CCAGAAGAAA CTACATTTCA CCTTCTACAC 
TTGTCTTTAA TGAGAGAGTA TATTGACTAT GAGTTTTCAG TATTAAAAGA AAAGATCACA 
TTTAAATATG ATATTGAAAG GATAATAGAT GATTGGATTT TGATGGGGTT TCTTGTTGGT 
AATGATTTTA TCCCTCATCT ACCTCATTTA CATATTAATC ATGATGCACT GCCTCTTCTT 
TATGGAACAT ATGTTACCAT CCTGCCAGAA CTTGGGGGTT ATATTAATGA AAGTGGGCAC 
CTCAACTTAC CTCGATTTGA GAAATACCTT GTGAAACTAT CAGATTTTGA TCGGGAGCAC 
TTCAGTGAAG TTTTTGTGGA CCTAAAATGG TTTGAAAGCA AAGTTGGTAA CAAGTACCTC 
AATGAAGCAG CAGGTGTCGC AGCAGAAGAA GCCAGGAACT ACAAGGAAAA GAAAAAGTTA 
AAGGGCCAGG AAAATTCTCT GTGTTGGACT GCTTTAGACA AAAATGAAGG CGAAATGATA 
ACTTCTAAGG ATAATTTAGA AGATGAGACT GAAGATGATG ACCTATTTGA AACTGAGTTT 
AGACAATATA AAAGAACATA TTACATGACG AAGATGGGGG TTGACGTAGT ATCTGATGAC 
TTTCTGGCTG ATCAAGCTGC ATGTTATGTT CAGGCAATAC AGTGGATTTT GCACTATTAC 
TATCATGGAG TTCAGTCCTG GAGCTGGTAT TATCCTTATC ATTATGCACC TTTCCTGTCT 
GATATACACA ACATCAGTAC ACTCAAAATC CATTTTGAAC TAGGAAAACC TTTTAAGCCA 
TTTGAACAGC TTCTTGCTGT ACTTCCAGCA GCCAGCAAAA ATTTACTTCC TGCATGCTAC 
CAGCATTTGA TGACCAATGA AGACTCACCA ATTATAGAAT ATTACCCACC TGATTTTAAA 
ACTGACCTAA ATGGGAAACA ACAGGAATGG GAAGCTGTGG TGTTAATCCC TTTTATTGAT 
GAGAAGCGAT TATTGGAAGC CATGGAGACA TGTAACCACT CCCTCAAAAA GGAAGAGAGG 
AAAAGAAACC AACATAGTGA GTGCCTAATG TGCTGGTATG ATAGAGACAC AGAGTTTATC 
TATCCTTCTC CATGGCCAGA AAAGTTCCCT GCCATAGAAC GATGTTGTAC AAGGTATAAA 
ATAATATCCT TAGATGCTTG GCGTGTAGAC ATAAACAAAA ACAAAATAAC CAGAATTGAC 
CAGAAAGCAT TATATTTCTG TGGATTTCCT ACTCTGAAAC ACATCAGACA CAAATTTTTT 
TTGAAGAAAA GTGGTGTTCA AGTATTCCAG CAAAGCAGTC GTGGAGAAAA CATGATGTTG 
GAAATCTTAG TGGATGCAGA ATCAGATGAA CTTACCGTAG AAAATGTAGC TTCATCAGTG 
CTTGGAAAAT CTGTCTTTGT TAATTGGCCT CACCTTGAGG AAGCTAGAGT CGTGGCTGTA 
TCAGATGGAG AAACTAAGTT TTACTTGGAA GAACCTCCAG GAACACAGAA GCTTTATTCA 
GGAAGAACTG CCCCACCATC TAAAGTGGTT CATCTTGGAG ATAAAGAACA ATCTAACTGG 
GCAAAAGAAG TACAAGGAAT TTCAGAACAC TACCTGAGAA GAAAAGGAAT AATAATAAAT 
GAAACATCTG CAGTTGTGTA TGCTCAGTTA CTCACAGGTC GTAAATATCA AATAAATCAA 
AATGGTGAAG TTCGTCTAGA GAAACAGTGG TCAAAACAAG TTGTTCCTTT TGTTTATCAA 
ACTATTGTCA AGGACATCCG AGCTTTCGAC TCCCGTTTCT CCAATATCAA AACATTGGAT 
GATTTGTTTC CTCTGAGAAG TATGGTCTTT ATGCTGGGAA CTCCCTATTA TGGCTGCACT 
GGAGAAGTTC AGGATTCAGG TGATGTGATT ACAGAAGGTA GGATTCGTGT GATTTTCAGC 
ATTCCATGTG AACCCAATCT TGATGCTTTA ATACAGAACC AGCATAAATA TTCTATAAAG 
TACAACCCAG GATATGTGTT GGCCAGTCGC CTTGGAGTGA GTGGATACCT TGTTTCAAGG 
TTTACAGGAA GTATTTTTAT TGGAAGAGGA TCTAGGAGAA ACCCTCATGG AGACCATAAA 
GCAAATGTGG GTTTAAATCT CAAATTCAAC AAGAAAAATG AGGAGGTACC TGGATATACT 
AAGAAAGTTG GAAGTGAATG GATGTATTCA TCTGCAGCAG AACAACTTCT GGCAGAGTAC 
TTAGAGAGAG CTCCAGAACT ATTTAGTTAT ATAGCCAAAA ATAGCCAAGA GGATGTGTTC 
TATGAAGATG ACATTTGGCC TGGAGAAAAT GAGAATGGTG CTGAAAAAGT TCAAGAAATT 
ATTACTTGGC TAAAAGGACA TCCTGTCAGT ACTTTATCTC GTTCTTCTTG TGATTTACAA 
ATTCTGGATG CAGCTATTGT TGAGAAAATT GAGGAAGAAG TCGAAAAGTG CAAGCAAAGA 
AAGAATAATA AGAAGGTGCG AGTAACAGTG AAACCCCATT TGCTATACAG ACCTTTAGAA 
CAGCAACATG GAGTCATTCC TGATCGGGAT GCAGAATTTT GTCTTTTTGA CCGTGTTGTA 
AATGTGAGAG AAAACTTCTC AGTTCCAGTT GGCCTTCGAG GCACCATCAT AGGAATAAAA 
GGAGCTAATA GAGAAGCCGA TGTACTATTT GAAGTATTAT TTGATGAAGA ATTTCCTGGA 
GGGTTAACAA TAAGATGCTC ACCTGGTAGA GGTTATCGAC TGCCAACAAG TGCCTTGGTG 
AACCTTTCTC ATGGGAGTCG CTCTGAAACT GGAAATCAGA AGTTGACAGC CATCGTAAAA 
CCACAACCAG CTGTACATCA ACATAGCTCA AGTTCATCAG TTTCCTCTGG GCATTTGGGA 
GCCCTCAACC ATTCCCCTCA ATCACTTTTT GTTCCTACTC AAGTACCTAC TAAAGATGAT 
GATGAATTCT GCAACATTTG GCAGTCCTTA CAGGGATCTG GAAAGATGCA ATACTTTCAG 
CCAACTATAC AAGAGAAGGG TGCAGTTCTA CCTCAAGAAA TAAGCCAAGT AAATCAACAT 
CATAAATCTG GCTTTAATGA CAACAGTGTT AAATATCAGC AAAGAAAACA TGACCCTCAC 
AGAAAATTTA AAGAAGAGTG TAAGAGTCCT AAAGCTGAGT GTTGGTCCCA AAAAATGTCC 
AATAAGCAGC CTAACTCTGG AATTGAGAAC TTTTTAGCAT CTTTGAATAT CTCCAAAGAA 
AATGAAGTAC AGTCATCTCA TCATGGGGAG CCTCCAAGTG AAGAGCATTT GTCACCACAG 
TCATTTGCCA TGAAGGGAAC ACGGATGCTT AAAGAAATTC TAAAAATTGA TGGCTCTAAC 
ACTGTGGACC ATAAGAATGA AATCAAACAG ATTGCTAATG AAATCCCTGT TTCCTCTAAC 
AGAAGAGATG AATATGGATT ACCCTCTCAG CCTAAACAAA ATAAGAAATT AGCATCTTAT 
ATGAACAAGC CTCACAGTGC TAATGAGTAC CATAATGTTC AGTCTATGGA CAATATGTGT 
TGGCCTGCCC CCAGCCAGAT CCCTCCTGTA TCCACACCAG TAACTGAACT TTCTCGAATT 
TGTTCCCTTG TTGGAATGCC ACAACCTGAT TTCTCCTTTC TTAGGATGCC ACAGACAATG 
ACCGTTTGCC AAGTAAAATT ATCTAATGGC TTACTGGTAC ATGGGCCACA GTGCCACTCT 
GAAAATGAAG CCAAAGAGAA AGCTGCACTT TTTGCTTTAC AACAGTTGGG CTCCTTAGGC 
ATGAATTTCC CTTTGCCTTC ACAAGTATTT GCAAATTATC CTTCAGCTGT ACCACCTGGA 
ACCATTCCTC CAGCCTTTCC CCCACCTACT GGCTGGGATC ACTATGGAAG CAACTATGCA 
TTGGGGGCAG CTAATATAAT GCCTTCGTCG TCTCATCTCT TTGGCTCAAT GCCATGGGGA 
CCATCGGTGC CAGTTCCTGG GAAGCCCTTC CATCATACTT TATATTCTGG GACCATGCCC 
ATGGCTGGGG GAATACCAGG GGGTGTGCAC AATCAGTTTA TACCTCTGCA GGTTACTAAA 
AAAAGGGTTG CAAACAAAAA GAACTTTGAG AATAAGGAAG CCCAGAGTTC TCAAGCCACT 
CCAGTTCAGA CTAGCCAGCC AGATTCTTCC AACATTGTCA AAGTAAGTCC ACGGGAGAGC 
TCATCAGCTT CTTTGAAGTC CTCTCCGATT GCTCAACCTG CATCTTCTTT TCAAGTTGAA 
ACTGCCTCTC AAGGCCATAG TATATCTCAC CATAAGTCAA CACCAATCTC TTCTTCAAGA 
AGAAAATCAA GAAAACTGGC TGTTAATTTT GGTGTTTCTA AACCTTCTGA GTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Gene Symbol	XRN1
Entrez Gene ID	54464
Full Name	5'-3' exoribonuclease 1
Synonyms	SEP1
General protein information	Preferred Names 5'-3' exoribonuclease 1 Names 5'-3' exoribonuclease 1 strand-exchange protein 1 homolog
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 3 Map Location: 3q23
Summary	This gene encodes a member of the 5'-3' exonuclease family. The encoded protein may be involved in replication-dependent histone mRNA degradation, and interacts directly with the enhancer of mRNA-decapping protein 4. In addition to mRNA metabolism, a similar protein in yeast has been implicated in a variety of nuclear and cytoplasmic functions, including homologous recombination, meiosis, telomere maintenance, and microtubule assembly. Mutations in this gene are associated with osteosarcoma, suggesting that the encoded protein may also play a role in bone formation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013].
Disorder MIM:	607994

Homo sapiens (human)	XRN1	NP_061874.3
Mus musculus (house mouse)	Xrn1	NP_036046.2
Rattus norvegicus (Norway rat)	Xrn1	XP_217233.5
Caenorhabditis elegans (roundworm)	xrn-1	NP_496945.3
Schizosaccharomyces pombe (fission yeast)	exo2	NP_593482.1
	XRN1	XP_001112305.1
Saccharomyces cerevisiae (baker's yeast)	XRN1	NP_011342.1
Magnaporthe oryzae (rice blast fungus)	MGG_12403	XP_003715558.1
Canis lupus familiaris (dog)	XRN1	XP_005634594.1
Danio rerio (zebrafish)	xrn1	NP_957327.2
Drosophila melanogaster (fruit fly)	pcm	NP_001162796.1
Eremothecium gossypii	AGOS_ADL046C	NP_984050.1
Neurospora crassa	NCU06678	XP_960925.2
Gallus gallus (chicken)	XRN1	XP_422596.3
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP004430	XP_313715.5
Xenopus tropicalis (tropical clawed frog)	xrn1	XP_002937144.2
Pan troglodytes (chimpanzee)	XRN1	XP_001161640.1
Bos taurus (cattle)	XRN1	NP_001192964.1
Kluyveromyces lactis	KLLA0F22385g	XP_456080.1

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

XRN1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

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Target ORF information:

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ORF Insert Sequence:

Target ORF information:

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ORF Insert Sequence:

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