FBXW5 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	FBXW5
Entrez Gene ID	54461
Full Name	F-box and WD repeat domain containing 5
Synonyms	Fbw5
General protein information	Preferred Names F-box and WD repeat domain containing 5 Names F-box/WD repeat-containing protein 5 F-box and WD-40 domain-containing protein 5 WD repeat-containing F-box protein FBW5
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 9 Map Location: 9q34.3
Summary	This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains WD-40 domains, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene, however, they were found to be nonsense-mediated mRNA decay (NMD) candidates, hence not represented. [provided by RefSeq, Jul 2008].
Disorder MIM:	609072

mRNA and Protein(s)

mRNA	Protein	Name
XM_017014812.1	XP_016870301.1	F-box/WD repeat-containing protein 5 isoform X3
NM_018998.3	NP_061871.1	F-box/WD repeat-containing protein 5
NM_018998.4	NP_061871.1	F-box/WD repeat-containing protein 5
XM_017014812.2	XP_016870301.1	F-box/WD repeat-containing protein 5 isoform X3
XM_011518789.1	XP_011517091.1	F-box/WD repeat-containing protein 5 isoform X2
XM_005266089.2	XP_005266146.2	F-box/WD repeat-containing protein 5 isoform X1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	FBXW5	XP_005625126.1
Rattus norvegicus (Norway rat)	Fbxw5	NP_001020901.1
Pan troglodytes (chimpanzee)	FBXW5	XP_003312463.1
Gallus gallus (chicken)	FBXW5	NP_001025865.1
Mus musculus (house mouse)	Fbxw5	NP_038936.1
Danio rerio (zebrafish)	fbxw5	NP_998484.1
Drosophila melanogaster (fruit fly)	Fbw5	NP_608989.1
Homo sapiens (human)	FBXW5	NP_061871.1
Bos taurus (cattle)	FBXW5	NP_001179398.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010041	XP_319186.4

Gene Ontology
Bibliography

Related articles in PubMed

A High-Density Map for Navigating the Human Polycomb Complexome.
Hauri S, Comoglio F, Seimiya M, Gerstung M, Glatter T, Hansen K, Aebersold R, Paro R, Gstaiger M, Beisel C
Cell reports17(2)583-595(2016 10)

Tnfaip8?l1/Oxi-? binds to FBXW5, increasing autophagy through activation of TSC2 in a Parkinson's disease model.
Ha JY, Kim JS, Kang YH, Bok E, Kim YS, Son JH
Journal of neurochemistry129(3)527-38(2014 May)

CRL4A-FBXW5-mediated degradation of DLC1 Rho GTPase-activating protein tumor suppressor promotes non-small cell lung cancer cell growth.
Kim TY, Jackson S, Xiong Y, Whitsett TG, Lobello JR, Weiss GJ, Tran NL, Bang YJ, Der CJ
Proceedings of the National Academy of Sciences of the United States of America110(42)16868-73(2013 Oct)

SCFFbxw5 mediates transient degradation of actin remodeller Eps8 to allow proper mitotic progression.
Werner A, Disanza A, Reifenberger N, Habeck G, Becker J, Calabrese M, Urlaub H, Lorenz H, Schulman B, Scita G, Melchior F
Nature cell biology15(2)179-88(2013 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

oxidative stress induces Tnfaip8 l1/Oxi-beta, which results in increased autophagy by its exclusive binding with FBXW5 to stabilize TSC2
Title: Tnfaip8?l1/Oxi-? binds to FBXW5, increasing autophagy through activation of TSC2 in a Parkinson's disease model.

DLC1 was ubiquitinated and degraded by cullin 4A-RING ubiquitin ligase (CRL4A) complex interaction with DDB1 and the FBXW5 substrate receptor.
Title: CRL4A-FBXW5-mediated degradation of DLC1 Rho GTPase-activating protein tumor suppressor promotes non-small cell lung cancer cell growth.

Identify Fbxw5-driven fluctuation of Eps8 levels as an important mechanism that contributes to cell-shape changes during entry into-and exit from-mitosis.
Title: SCFFbxw5 mediates transient degradation of actin remodeller Eps8 to allow proper mitotic progression.

Fbxw5 enhances sumoylation of nuclear c-Myb
Title: Fbxw5 suppresses nuclear c-Myb activity via DDB1-Cul4-Rbx1 ligase-mediated sumoylation.

FBXW5 levels are controlled by the anaphase-promoting (APC/C) complex, which targets FBXW5 for degradation during mitosis and G1, thereby helping to reset the centrosome duplication machinery.
Title: The SCF-FBXW5 E3-ubiquitin ligase is regulated by PLK4 and targets HsSAS-6 to control centrosome duplication.

The following FBXW5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FBXW5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu16830	NM_018998.4 Latest version!	Homo sapiens F-box and WD repeat domain containing 5 (FBXW5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
OHu68337	XM_005266089.2 Latest version!	Homo sapiens F-box and WD repeat domain containing 5 (FBXW5), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu68338	XM_011518789.1 Latest version!	Homo sapiens F-box and WD repeat domain containing 5 (FBXW5), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu98696	XM_017014812.2 Latest version!	Homo sapiens F-box and WD repeat domain containing 5 (FBXW5), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
View Old Accession Versions >>
OHu16830	NM_018998.3	Homo sapiens F-box and WD repeat domain containing 5 (FBXW5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
OHu98696	XM_017014812.1	Homo sapiens F-box and WD repeat domain containing 5 (FBXW5), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

FBXW5 ( NM_018998.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_061871.1 Homo sapiens F-box and WD repeat domain containing 5 (FBXW5), mRNA.

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CloneID	OHu16830
Clone ID Related Accession (Same CDS sequence)	NM_018998.3 , NM_018998.4
Accession Version	NM_018998.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1701bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	F-box/WD repeat-containing protein 5
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CF132404.1, DB460097.1, BC014130.1 and EC577580.1. On Dec 9, 2011 this sequence version replaced NM_018998.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163657.37507.1, BC014130.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148874 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGACGAGG GCGGCACGCC CCTGCTCCCC GACAGCCTGG TCTACCAGAT CTTCCTGAGC 
CTGGGCCCGG CCGACGTGCT GGCCGCCGGG CTGGTGTGCC GCCAATGGCA GGCCGTGTCG 
CGGGACGAGT TCCTGTGGAG GGAGCAGTTC TACCGCTACT ACCAGGTGGC CCGCGACGTG 
CCCCGACACC CAGCGGCCAT GTCCTGGTAC GAGGAGTTCC AGCGGCTGTA TGACACGGTG 
CCCTGCGTGG AGGTGCAGAC GCTGCGGGAA CACACAGACC AGGTCCTGCA CCTCAGCTTC 
TCCCATTCCG GGTACCAGTT CGCGTCCTGC TCCAAGGACT GCACTGTGAA GATCTGGAGC 
AACGACCTGA CCATCTCGCT GCTGCACAGC GCGGACATGC GGCCCTACAA CTGGAGCTAC 
ACCCAGTTCT CCCAGTTCAA CAAGGACGAC TCGCTACTGC TGGCCTCGGG GGTGTTCCTG 
GGGCCGCACA ACTCCTCATC CGGCGAGATT GCTGTCATCA GCCTAGACTC CTTCGCGCTG 
CTGTCCCGCG TGCGGAACAA GCCCTATGAC GTGTTTGGCT GTTGGCTCAC CGAGACCAGC 
CTCATCTCGG GGAACCTGCA CCGCATCGGA GATATCACCT CCTGCTCGGT GCTGTGGCTC 
AACAATGCCT TCCAGGATGT GGAGTCAGAG AACGTCAACG TGGTGAAGCG GCTGTTCAAG 
ATCCAGAACC TCAATGCCAG CACCGTCCGC ACGGTGATGG TGGCCGACTG CAGCCGCTTC 
GACAGCCCTG ACCTGCTGCT GGAAGCCGGT GACCCGGCCA CGTCCCCCTG CCGCATCTTT 
GACCTGGGCA GCGACAACGA GGAGGTGGTG GCTGGCCCGG CCCCCGCCCA CGCCAAGGAG 
GGCTTGCGGC ACTTTCTGGA CCGCGTGCTG GAGGGGCGGG CGCAGCCACA GCTGTCGGAG 
CGCATGCTAG AGACCAAGGT GGCCGAGCTG CTGGCCCAGG GCCACACCAA GCCACCCGAG 
CGCAGTGCCA CAGGCGCCAA GAGCAAGTAC CTCATCTTCA CCACTGGCTG CCTCACCTAC 
TCCCCACACC AGATCGGCAT CAAGCAGATC CTGCCACACC AGATGACCAC GGCAGGGCCC 
GTGCTGGGTG AGGGCCGGGG CTCCGATGCC TTCTTCGACG CGCTGGACCA CGTCATAGAC 
ATACACGGAC ACATCATCGG CATGGGCCTG TCGCCCGACA ACAGGTACCT GTACGTGAAC 
AGCCGCGCCT GGCCCAACGG TGCGGTGGTG GCCGACCCCA TGCAGCCGCC ACCAATCGCG 
GAGGAGATTG ACCTGCTGGT GTTCGACCTC AAGACCATGC GGGAGGTGAG GCGGGCTCTG 
CGTGCGCACC GCGCCTACAC GCCCAACGAC GAGTGCTTCT TCATCTTCCT GGACGTCAGC 
AGGGACTTCG TGGCCAGCGG GGCGGAGGAC CGGCACGGCT ACATCTGGGA CCGCCACTAC 
AACATCTGTC TGGCCAGGCT GCGGCACGAG GATGTGGTCA ACTCAGTGGT CTTCAGTCCC 
CAGGAGCAGG AGCTGCTGCT CACGGCCAGC GACGACGCCA CCATCAAAGC CTGGCGCTCC 
CCACGCACCA TGCGCGTCCT CCAGGCACCT CGCCCACGGC CTCGCACCTT CTTCTCCTGG 
CTTGCCAGCC AGAGGCGCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_061871.1
CDS	185..1885
Translation	MDEGGTPLLPDSLVYQIFLSLGPADVLAAGLVCRQWQAVSRDEFLWREQFYRYYQVARDVPRHPAAMSWYEEFQRLYDTVPCVEVQTLREHTDQVLHLSFSHSGYQFASCSKDCTVKIWSNDLTISLLHSADMRPYNWSYTQFSQFNKDDSLLLASGVFLGPHNSSSGEIAVISLDSFALLSRVRNKPYDVFGCWLTETSLISGNLHRIGDITSCSVLWLNNAFQDVESENVNVVKRLFKIQNLNASTVRTVMVADCSRFDSPDLLLEAGDPATSPCRIFDLGSDNEEVVAGPAPAHAKEGLRHFLDRVLEGRAQPQLSERMLETKVAELLAQGHTKPPERSATGAKSKYLIFTTGCLTYSPHQIGIKQILPHQMTTAGPVLGEGRGSDAFFDALDHVIDIHGHIIGMGLSPDNRYLYVNSRAWPNGAVVADPMQPPPIAEEIDLLVFDLKTMREVRRALRAHRAYTPNDECFFIFLDVSRDFVASGAEDRHGYIWDRHYNICLARLRHEDVVNSVVFSPQEQELLLTASDDATIKAWRSPRTMRVLQAPRPRPRTFFSWLASQRR

Target ORF information:

RefSeq Version	NM_018998.3
Organism	Homo sapiens(human)
Definition	Homo sapiens F-box and WD repeat domain containing 5 (FBXW5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018998.3

ORF Insert Sequence:

ATGGACGAGG GCGGCACGCC CCTGCTCCCC GACAGCCTGG TCTACCAGAT CTTCCTGAGC 
CTGGGCCCGG CCGACGTGCT GGCCGCCGGG CTGGTGTGCC GCCAATGGCA GGCCGTGTCG 
CGGGACGAGT TCCTGTGGAG GGAGCAGTTC TACCGCTACT ACCAGGTGGC CCGCGACGTG 
CCCCGACACC CAGCGGCCAT GTCCTGGTAC GAGGAGTTCC AGCGGCTGTA TGACACGGTG 
CCCTGCGTGG AGGTGCAGAC GCTGCGGGAA CACACAGACC AGGTCCTGCA CCTCAGCTTC 
TCCCATTCCG GGTACCAGTT CGCGTCCTGC TCCAAGGACT GCACTGTGAA GATCTGGAGC 
AACGACCTGA CCATCTCGCT GCTGCACAGC GCGGACATGC GGCCCTACAA CTGGAGCTAC 
ACCCAGTTCT CCCAGTTCAA CAAGGACGAC TCGCTACTGC TGGCCTCGGG GGTGTTCCTG 
GGGCCGCACA ACTCCTCATC CGGCGAGATT GCTGTCATCA GCCTAGACTC CTTCGCGCTG 
CTGTCCCGCG TGCGGAACAA GCCCTATGAC GTGTTTGGCT GTTGGCTCAC CGAGACCAGC 
CTCATCTCGG GGAACCTGCA CCGCATCGGA GATATCACCT CCTGCTCGGT GCTGTGGCTC 
AACAATGCCT TCCAGGATGT GGAGTCAGAG AACGTCAACG TGGTGAAGCG GCTGTTCAAG 
ATCCAGAACC TCAATGCCAG CACCGTCCGC ACGGTGATGG TGGCCGACTG CAGCCGCTTC 
GACAGCCCTG ACCTGCTGCT GGAAGCCGGT GACCCGGCCA CGTCCCCCTG CCGCATCTTT 
GACCTGGGCA GCGACAACGA GGAGGTGGTG GCTGGCCCGG CCCCCGCCCA CGCCAAGGAG 
GGCTTGCGGC ACTTTCTGGA CCGCGTGCTG GAGGGGCGGG CGCAGCCACA GCTGTCGGAG 
CGCATGCTAG AGACCAAGGT GGCCGAGCTG CTGGCCCAGG GCCACACCAA GCCACCCGAG 
CGCAGTGCCA CAGGCGCCAA GAGCAAGTAC CTCATCTTCA CCACTGGCTG CCTCACCTAC 
TCCCCACACC AGATCGGCAT CAAGCAGATC CTGCCACACC AGATGACCAC GGCAGGGCCC 
GTGCTGGGTG AGGGCCGGGG CTCCGATGCC TTCTTCGACG CGCTGGACCA CGTCATAGAC 
ATACACGGAC ACATCATCGG CATGGGCCTG TCGCCCGACA ACAGGTACCT GTACGTGAAC 
AGCCGCGCCT GGCCCAACGG TGCGGTGGTG GCCGACCCCA TGCAGCCGCC ACCAATCGCG 
GAGGAGATTG ACCTGCTGGT GTTCGACCTC AAGACCATGC GGGAGGTGAG GCGGGCTCTG 
CGTGCGCACC GCGCCTACAC GCCCAACGAC GAGTGCTTCT TCATCTTCCT GGACGTCAGC 
AGGGACTTCG TGGCCAGCGG GGCGGAGGAC CGGCACGGCT ACATCTGGGA CCGCCACTAC 
AACATCTGTC TGGCCAGGCT GCGGCACGAG GATGTGGTCA ACTCAGTGGT CTTCAGTCCC 
CAGGAGCAGG AGCTGCTGCT CACGGCCAGC GACGACGCCA CCATCAAAGC CTGGCGCTCC 
CCACGCACCA TGCGCGTCCT CCAGGCACCT CGCCCACGGC CTCGCACCTT CTTCTCCTGG 
CTTGCCAGCC AGAGGCGCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FBXW5 ( NM_018998.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_061871.1 Homo sapiens F-box and WD repeat domain containing 5 (FBXW5), mRNA.

Price & Availability↑

CloneID	OHu16830
Clone ID Related Accession (Same CDS sequence)	NM_018998.3 , NM_018998.4
Accession Version	NM_018998.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1701bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	F-box/WD repeat-containing protein 5
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CF132404.1, DB460097.1 and BC014130.1. On Nov 22, 2018 this sequence version replaced NM_018998.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.31293.1, SRR3476690.293664.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000325285.8/ ENSP00000313034.3 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGACGAGG GCGGCACGCC CCTGCTCCCC GACAGCCTGG TCTACCAGAT CTTCCTGAGC 
CTGGGCCCGG CCGACGTGCT GGCCGCCGGG CTGGTGTGCC GCCAATGGCA GGCCGTGTCG 
CGGGACGAGT TCCTGTGGAG GGAGCAGTTC TACCGCTACT ACCAGGTGGC CCGCGACGTG 
CCCCGACACC CAGCGGCCAT GTCCTGGTAC GAGGAGTTCC AGCGGCTGTA TGACACGGTG 
CCCTGCGTGG AGGTGCAGAC GCTGCGGGAA CACACAGACC AGGTCCTGCA CCTCAGCTTC 
TCCCATTCCG GGTACCAGTT CGCGTCCTGC TCCAAGGACT GCACTGTGAA GATCTGGAGC 
AACGACCTGA CCATCTCGCT GCTGCACAGC GCGGACATGC GGCCCTACAA CTGGAGCTAC 
ACCCAGTTCT CCCAGTTCAA CAAGGACGAC TCGCTACTGC TGGCCTCGGG GGTGTTCCTG 
GGGCCGCACA ACTCCTCATC CGGCGAGATT GCTGTCATCA GCCTAGACTC CTTCGCGCTG 
CTGTCCCGCG TGCGGAACAA GCCCTATGAC GTGTTTGGCT GTTGGCTCAC CGAGACCAGC 
CTCATCTCGG GGAACCTGCA CCGCATCGGA GATATCACCT CCTGCTCGGT GCTGTGGCTC 
AACAATGCCT TCCAGGATGT GGAGTCAGAG AACGTCAACG TGGTGAAGCG GCTGTTCAAG 
ATCCAGAACC TCAATGCCAG CACCGTCCGC ACGGTGATGG TGGCCGACTG CAGCCGCTTC 
GACAGCCCTG ACCTGCTGCT GGAAGCCGGT GACCCGGCCA CGTCCCCCTG CCGCATCTTT 
GACCTGGGCA GCGACAACGA GGAGGTGGTG GCTGGCCCGG CCCCCGCCCA CGCCAAGGAG 
GGCTTGCGGC ACTTTCTGGA CCGCGTGCTG GAGGGGCGGG CGCAGCCACA GCTGTCGGAG 
CGCATGCTAG AGACCAAGGT GGCCGAGCTG CTGGCCCAGG GCCACACCAA GCCACCCGAG 
CGCAGTGCCA CAGGCGCCAA GAGCAAGTAC CTCATCTTCA CCACTGGCTG CCTCACCTAC 
TCCCCACACC AGATCGGCAT CAAGCAGATC CTGCCACACC AGATGACCAC GGCAGGGCCC 
GTGCTGGGTG AGGGCCGGGG CTCCGATGCC TTCTTCGACG CGCTGGACCA CGTCATAGAC 
ATACACGGAC ACATCATCGG CATGGGCCTG TCGCCCGACA ACAGGTACCT GTACGTGAAC 
AGCCGCGCCT GGCCCAACGG TGCGGTGGTG GCCGACCCCA TGCAGCCGCC ACCAATCGCG 
GAGGAGATTG ACCTGCTGGT GTTCGACCTC AAGACCATGC GGGAGGTGAG GCGGGCTCTG 
CGTGCGCACC GCGCCTACAC GCCCAACGAC GAGTGCTTCT TCATCTTCCT GGACGTCAGC 
AGGGACTTCG TGGCCAGCGG GGCGGAGGAC CGGCACGGCT ACATCTGGGA CCGCCACTAC 
AACATCTGTC TGGCCAGGCT GCGGCACGAG GATGTGGTCA ACTCAGTGGT CTTCAGTCCC 
CAGGAGCAGG AGCTGCTGCT CACGGCCAGC GACGACGCCA CCATCAAAGC CTGGCGCTCC 
CCACGCACCA TGCGCGTCCT CCAGGCACCT CGCCCACGGC CTCGCACCTT CTTCTCCTGG 
CTTGCCAGCC AGAGGCGCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_061871.1
CDS	169..1869
Translation	MDEGGTPLLPDSLVYQIFLSLGPADVLAAGLVCRQWQAVSRDEFLWREQFYRYYQVARDVPRHPAAMSWYEEFQRLYDTVPCVEVQTLREHTDQVLHLSFSHSGYQFASCSKDCTVKIWSNDLTISLLHSADMRPYNWSYTQFSQFNKDDSLLLASGVFLGPHNSSSGEIAVISLDSFALLSRVRNKPYDVFGCWLTETSLISGNLHRIGDITSCSVLWLNNAFQDVESENVNVVKRLFKIQNLNASTVRTVMVADCSRFDSPDLLLEAGDPATSPCRIFDLGSDNEEVVAGPAPAHAKEGLRHFLDRVLEGRAQPQLSERMLETKVAELLAQGHTKPPERSATGAKSKYLIFTTGCLTYSPHQIGIKQILPHQMTTAGPVLGEGRGSDAFFDALDHVIDIHGHIIGMGLSPDNRYLYVNSRAWPNGAVVADPMQPPPIAEEIDLLVFDLKTMREVRRALRAHRAYTPNDECFFIFLDVSRDFVASGAEDRHGYIWDRHYNICLARLRHEDVVNSVVFSPQEQELLLTASDDATIKAWRSPRTMRVLQAPRPRPRTFFSWLASQRR

Target ORF information:

RefSeq Version	NM_018998.4
Organism	Homo sapiens(human)
Definition	Homo sapiens F-box and WD repeat domain containing 5 (FBXW5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018998.4

ORF Insert Sequence:

ATGGACGAGG GCGGCACGCC CCTGCTCCCC GACAGCCTGG TCTACCAGAT CTTCCTGAGC 
CTGGGCCCGG CCGACGTGCT GGCCGCCGGG CTGGTGTGCC GCCAATGGCA GGCCGTGTCG 
CGGGACGAGT TCCTGTGGAG GGAGCAGTTC TACCGCTACT ACCAGGTGGC CCGCGACGTG 
CCCCGACACC CAGCGGCCAT GTCCTGGTAC GAGGAGTTCC AGCGGCTGTA TGACACGGTG 
CCCTGCGTGG AGGTGCAGAC GCTGCGGGAA CACACAGACC AGGTCCTGCA CCTCAGCTTC 
TCCCATTCCG GGTACCAGTT CGCGTCCTGC TCCAAGGACT GCACTGTGAA GATCTGGAGC 
AACGACCTGA CCATCTCGCT GCTGCACAGC GCGGACATGC GGCCCTACAA CTGGAGCTAC 
ACCCAGTTCT CCCAGTTCAA CAAGGACGAC TCGCTACTGC TGGCCTCGGG GGTGTTCCTG 
GGGCCGCACA ACTCCTCATC CGGCGAGATT GCTGTCATCA GCCTAGACTC CTTCGCGCTG 
CTGTCCCGCG TGCGGAACAA GCCCTATGAC GTGTTTGGCT GTTGGCTCAC CGAGACCAGC 
CTCATCTCGG GGAACCTGCA CCGCATCGGA GATATCACCT CCTGCTCGGT GCTGTGGCTC 
AACAATGCCT TCCAGGATGT GGAGTCAGAG AACGTCAACG TGGTGAAGCG GCTGTTCAAG 
ATCCAGAACC TCAATGCCAG CACCGTCCGC ACGGTGATGG TGGCCGACTG CAGCCGCTTC 
GACAGCCCTG ACCTGCTGCT GGAAGCCGGT GACCCGGCCA CGTCCCCCTG CCGCATCTTT 
GACCTGGGCA GCGACAACGA GGAGGTGGTG GCTGGCCCGG CCCCCGCCCA CGCCAAGGAG 
GGCTTGCGGC ACTTTCTGGA CCGCGTGCTG GAGGGGCGGG CGCAGCCACA GCTGTCGGAG 
CGCATGCTAG AGACCAAGGT GGCCGAGCTG CTGGCCCAGG GCCACACCAA GCCACCCGAG 
CGCAGTGCCA CAGGCGCCAA GAGCAAGTAC CTCATCTTCA CCACTGGCTG CCTCACCTAC 
TCCCCACACC AGATCGGCAT CAAGCAGATC CTGCCACACC AGATGACCAC GGCAGGGCCC 
GTGCTGGGTG AGGGCCGGGG CTCCGATGCC TTCTTCGACG CGCTGGACCA CGTCATAGAC 
ATACACGGAC ACATCATCGG CATGGGCCTG TCGCCCGACA ACAGGTACCT GTACGTGAAC 
AGCCGCGCCT GGCCCAACGG TGCGGTGGTG GCCGACCCCA TGCAGCCGCC ACCAATCGCG 
GAGGAGATTG ACCTGCTGGT GTTCGACCTC AAGACCATGC GGGAGGTGAG GCGGGCTCTG 
CGTGCGCACC GCGCCTACAC GCCCAACGAC GAGTGCTTCT TCATCTTCCT GGACGTCAGC 
AGGGACTTCG TGGCCAGCGG GGCGGAGGAC CGGCACGGCT ACATCTGGGA CCGCCACTAC 
AACATCTGTC TGGCCAGGCT GCGGCACGAG GATGTGGTCA ACTCAGTGGT CTTCAGTCCC 
CAGGAGCAGG AGCTGCTGCT CACGGCCAGC GACGACGCCA CCATCAAAGC CTGGCGCTCC 
CCACGCACCA TGCGCGTCCT CCAGGCACCT CGCCCACGGC CTCGCACCTT CTTCTCCTGG 
CTTGCCAGCC AGAGGCGCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FBXW5 ( XM_005266089.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_005266146.2 Homo sapiens F-box and WD repeat domain containing 5 (FBXW5), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu68337
Clone ID Related Accession (Same CDS sequence)	XM_005266089.2
Accession Version	XM_005266089.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1731bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	F-box/WD repeat-containing protein 5 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000009.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced XM_005266089.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACGAGG GCGGCACGCC CCTGCTCCCC GACAGCCTGG TCTACCAGAT CTTCCTGAGC 
CTGGGCCCGG CCGACGTGCT GGCCGCCGGG CTGGTGTGCC GCCAATGGCA GGCCGTGTCG 
CGGGACGAGT TCCTGTGGAG GGAGCAGTTC TACCGCTACT ACCAGGTGGC CCGCGACGTG 
CCCCGACACC CAGCGGCCAT GTCCTGGTAC GAGGAGTTCC AGCGGCTGTA TGACACGGTG 
CCCTGCGTGG AGGTGCAGAC GCTGCGGGAA CACACAGACC AGGTCCTGCA CCTCAGCTTC 
TCCCATTCCG GGTACCAGTT CGCGTCCTGC TCCAAGGACT GCACTGTGAA GGCGATCACT 
ACAGCCGCCC CTGCCGAACA GATCTGGAGC AACGACCTGA CCATCTCGCT GCTGCACAGC 
GCGGACATGC GGCCCTACAA CTGGAGCTAC ACCCAGTTCT CCCAGTTCAA CAAGGACGAC 
TCGCTACTGC TGGCCTCGGG GGTGTTCCTG GGGCCGCACA ACTCCTCATC CGGCGAGATT 
GCTGTCATCA GCCTAGACTC CTTCGCGCTG CTGTCCCGCG TGCGGAACAA GCCCTATGAC 
GTGTTTGGCT GTTGGCTCAC CGAGACCAGC CTCATCTCGG GGAACCTGCA CCGCATCGGA 
GATATCACCT CCTGCTCGGT GCTGTGGCTC AACAATGCCT TCCAGGATGT GGAGTCAGAG 
AACGTCAACG TGGTGAAGCG GCTGTTCAAG ATCCAGAACC TCAATGCCAG CACCGTCCGC 
ACGGTGATGG TGGCCGACTG CAGCCGCTTC GACAGCCCTG ACCTGCTGCT GGAAGCCGGT 
GACCCGGCCA CGTCCCCCTG CCGCATCTTT GACCTGGGCA GCGACAACGA GGAGGTGGTG 
GCTGGCCCGG CCCCCGCCCA CGCCAAGGAG GGCTTGCGGC ACTTTCTGGA CCGCGTGCTG 
GAGGGGCGGG CGCAGCCACA GCTGTCGGAG CGCATGCTAG AGACCAAGGT GGCCGAGCTG 
CTGGCCCAGG GCCACACCAA GCCACCCGAG CGCAGTGCCA CAGGCGCCAA GAGCAAGTAC 
CTCATCTTCA CCACTGGCTG CCTCACCTAC TCCCCACACC AGATCGGCAT CAAGCAGATC 
CTGCCACACC AGATGACCAC GGCAGGGCCC GTGCTGGGTG AGGGCCGGGG CTCCGATGCC 
TTCTTCGACG CGCTGGACCA CGTCATAGAC ATACACGGAC ACATCATCGG CATGGGCCTG 
TCGCCCGACA ACAGGTACCT GTACGTGAAC AGCCGCGCCT GGCCCAACGG TGCGGTGGTG 
GCCGACCCCA TGCAGCCGCC ACCAATCGCG GAGGAGATTG ACCTGCTGGT GTTCGACCTC 
AAGACCATGC GGGAGGTGAG GCGGGCTCTG CGTGCGCACC GCGCCTACAC GCCCAACGAC 
GAGTGCTTCT TCATCTTCCT GGACGTCAGC AGGGACTTCG TGGCCAGCGG GGCGGAGGAC 
CGGCACGGCT ACATCTGGGA CCGCCACTAC AACATCTGTC TGGCCAGGCT GCGGCACGAG 
GATGTGGTCA ACTCAGTGGT CTTCAGTCCC CAGGAGCAGG AGCTGCTGCT CACGGCCAGC 
GACGACGCCA CCATCAAAGC CTGGCGCTCC CCACGCACCA TGCGCGTCCT CCAGGCACCT 
CGCCCACGGC CTCGCACCTT CTTCTCCTGG CTTGCCAGCC AGAGGCGCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005266146.2
CDS	205..1935
Translation	MDEGGTPLLPDSLVYQIFLSLGPADVLAAGLVCRQWQAVSRDEFLWREQFYRYYQVARDVPRHPAAMSWYEEFQRLYDTVPCVEVQTLREHTDQVLHLSFSHSGYQFASCSKDCTVKAITTAAPAEQIWSNDLTISLLHSADMRPYNWSYTQFSQFNKDDSLLLASGVFLGPHNSSSGEIAVISLDSFALLSRVRNKPYDVFGCWLTETSLISGNLHRIGDITSCSVLWLNNAFQDVESENVNVVKRLFKIQNLNASTVRTVMVADCSRFDSPDLLLEAGDPATSPCRIFDLGSDNEEVVAGPAPAHAKEGLRHFLDRVLEGRAQPQLSERMLETKVAELLAQGHTKPPERSATGAKSKYLIFTTGCLTYSPHQIGIKQILPHQMTTAGPVLGEGRGSDAFFDALDHVIDIHGHIIGMGLSPDNRYLYVNSRAWPNGAVVADPMQPPPIAEEIDLLVFDLKTMREVRRALRAHRAYTPNDECFFIFLDVSRDFVASGAEDRHGYIWDRHYNICLARLRHEDVVNSVVFSPQEQELLLTASDDATIKAWRSPRTMRVLQAPRPRPRTFFSWLASQRR

Target ORF information:

RefSeq Version	XM_005266089.2
Organism	Homo sapiens(human)
Definition	Homo sapiens F-box and WD repeat domain containing 5 (FBXW5), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005266089.2

ORF Insert Sequence:

ATGGACGAGG GCGGCACGCC CCTGCTCCCC GACAGCCTGG TCTACCAGAT CTTCCTGAGC 
CTGGGCCCGG CCGACGTGCT GGCCGCCGGG CTGGTGTGCC GCCAATGGCA GGCCGTGTCG 
CGGGACGAGT TCCTGTGGAG GGAGCAGTTC TACCGCTACT ACCAGGTGGC CCGCGACGTG 
CCCCGACACC CAGCGGCCAT GTCCTGGTAC GAGGAGTTCC AGCGGCTGTA TGACACGGTG 
CCCTGCGTGG AGGTGCAGAC GCTGCGGGAA CACACAGACC AGGTCCTGCA CCTCAGCTTC 
TCCCATTCCG GGTACCAGTT CGCGTCCTGC TCCAAGGACT GCACTGTGAA GGCGATCACT 
ACAGCCGCCC CTGCCGAACA GATCTGGAGC AACGACCTGA CCATCTCGCT GCTGCACAGC 
GCGGACATGC GGCCCTACAA CTGGAGCTAC ACCCAGTTCT CCCAGTTCAA CAAGGACGAC 
TCGCTACTGC TGGCCTCGGG GGTGTTCCTG GGGCCGCACA ACTCCTCATC CGGCGAGATT 
GCTGTCATCA GCCTAGACTC CTTCGCGCTG CTGTCCCGCG TGCGGAACAA GCCCTATGAC 
GTGTTTGGCT GTTGGCTCAC CGAGACCAGC CTCATCTCGG GGAACCTGCA CCGCATCGGA 
GATATCACCT CCTGCTCGGT GCTGTGGCTC AACAATGCCT TCCAGGATGT GGAGTCAGAG 
AACGTCAACG TGGTGAAGCG GCTGTTCAAG ATCCAGAACC TCAATGCCAG CACCGTCCGC 
ACGGTGATGG TGGCCGACTG CAGCCGCTTC GACAGCCCTG ACCTGCTGCT GGAAGCCGGT 
GACCCGGCCA CGTCCCCCTG CCGCATCTTT GACCTGGGCA GCGACAACGA GGAGGTGGTG 
GCTGGCCCGG CCCCCGCCCA CGCCAAGGAG GGCTTGCGGC ACTTTCTGGA CCGCGTGCTG 
GAGGGGCGGG CGCAGCCACA GCTGTCGGAG CGCATGCTAG AGACCAAGGT GGCCGAGCTG 
CTGGCCCAGG GCCACACCAA GCCACCCGAG CGCAGTGCCA CAGGCGCCAA GAGCAAGTAC 
CTCATCTTCA CCACTGGCTG CCTCACCTAC TCCCCACACC AGATCGGCAT CAAGCAGATC 
CTGCCACACC AGATGACCAC GGCAGGGCCC GTGCTGGGTG AGGGCCGGGG CTCCGATGCC 
TTCTTCGACG CGCTGGACCA CGTCATAGAC ATACACGGAC ACATCATCGG CATGGGCCTG 
TCGCCCGACA ACAGGTACCT GTACGTGAAC AGCCGCGCCT GGCCCAACGG TGCGGTGGTG 
GCCGACCCCA TGCAGCCGCC ACCAATCGCG GAGGAGATTG ACCTGCTGGT GTTCGACCTC 
AAGACCATGC GGGAGGTGAG GCGGGCTCTG CGTGCGCACC GCGCCTACAC GCCCAACGAC 
GAGTGCTTCT TCATCTTCCT GGACGTCAGC AGGGACTTCG TGGCCAGCGG GGCGGAGGAC 
CGGCACGGCT ACATCTGGGA CCGCCACTAC AACATCTGTC TGGCCAGGCT GCGGCACGAG 
GATGTGGTCA ACTCAGTGGT CTTCAGTCCC CAGGAGCAGG AGCTGCTGCT CACGGCCAGC 
GACGACGCCA CCATCAAAGC CTGGCGCTCC CCACGCACCA TGCGCGTCCT CCAGGCACCT 
CGCCCACGGC CTCGCACCTT CTTCTCCTGG CTTGCCAGCC AGAGGCGCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FBXW5 ( XM_011518789.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011517091.1 Homo sapiens F-box and WD repeat domain containing 5 (FBXW5), transcript variant X2, mRNA.

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CloneID	OHu68338
Clone ID Related Accession (Same CDS sequence)	XM_011518789.1
Accession Version	XM_011518789.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1677bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	F-box/WD repeat-containing protein 5 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000009.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACGAGG GCGGCACGCC CCTGCTCCCC GACAGCCTGG TCTACCAGAT CTTCCTGAGC 
CTGGGCCCGG CCGACGTGCT GGCCGCCGGG CTGGTGTGCC GCCAATGGCA GGCCGTGTCG 
CGGGACGAGT TCCTGTGGAG GGAGCAGTTC TACCGCTACT ACCAGGTGGC CCGCGACGTG 
CCCCGACACC CAGCGGCCAT GTCCTGGTAC GAGGAGTTCC AGCGGCTGTA TGACACGGTG 
CCCTGCGTGG AGGTGCAGAC GCTGCGGGAA CACACAGACC AGGTCCTGCA CCTCAGCTTC 
TCCCATTCCG GGTACCAGTT CGCGTCCTGC TCCAAGGACT GCACTGTGAA GGCGATCACT 
ACAGCCGCCC CTGCCGAACA GATCTGGAGC AACGACCTGA CCATCTCGCT GCTGCACAGC 
GCGGACATGC GGCCCTACAA CTGGAGCTAC ACCCAGTTCT CCCAGTTCAA CAAGGACGAC 
TCGCTACTGC TGGCCTCGGG GGTGTTCCTG GGGCCGCACA ACTCCTCATC CGGCGAGATT 
GCTGTCATCA GCCTAGACTC CTTCGCGCTG CTGTCCCGCG TGCGGAACAA GCCCTATGAC 
GTGTTTGGCT GTTGGCTCAC CGAGACCAGC CTCATCTCGG GGAACCTGCA CCGCATCGGA 
GATATCACCT CCTGCTCGGT GCTGTGGCTC AACAATGCCT TCCAGGATGT GGAGTCAGAG 
AACGTCAACG TGGTGAAGCG GCTGTTCAAG ATCCAGAACC TCAATGCCAG CACCGTCCGC 
ACGGTGATGG TGGCCGACTG CAGCCGCTTC GACAGCCCTG ACCTGCTGCT GGAAGCCGGT 
GACCCGGCCA CGTCCCCCTG CCGCATCTTT GACCTGGGCA GCGACAACGA GGAGGTGGTG 
GCTGGCCCGG CCCCCGCCCA CGCCAAGGAG GGCTTGCGGC ACTTTCTGGA CCGCGTGCTG 
GAGGGGCGGG CGCAGCCACA GCTGTCGGAG CGCATGCTAG AGACCAAGGT GGCCGAGCTG 
CTGGCCCAGG GCCACACCAA GCCACCCGAG CGCAGTGCCA CAGGCGCCAA GAGCATCAAG 
CAGATCCTGC CACACCAGAT GACCACGGCA GGGCCCGTGC TGGGTGAGGG CCGGGGCTCC 
GATGCCTTCT TCGACGCGCT GGACCACGTC ATAGACATAC ACGGACACAT CATCGGCATG 
GGCCTGTCGC CCGACAACAG GTACCTGTAC GTGAACAGCC GCGCCTGGCC CAACGGTGCG 
GTGGTGGCCG ACCCCATGCA GCCGCCACCA ATCGCGGAGG AGATTGACCT GCTGGTGTTC 
GACCTCAAGA CCATGCGGGA GGTGAGGCGG GCTCTGCGTG CGCACCGCGC CTACACGCCC 
AACGACGAGT GCTTCTTCAT CTTCCTGGAC GTCAGCAGGG ACTTCGTGGC CAGCGGGGCG 
GAGGACCGGC ACGGCTACAT CTGGGACCGC CACTACAACA TCTGTCTGGC CAGGCTGCGG 
CACGAGGATG TGGTCAACTC AGTGGTCTTC AGTCCCCAGG AGCAGGAGCT GCTGCTCACG 
GCCAGCGACG ACGCCACCAT CAAAGCCTGG CGCTCCCCAC GCACCATGCG CGTCCTCCAG 
GCACCTCGCC CACGGCCTCG CACCTTCTTC TCCTGGCTTG CCAGCCAGAG GCGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011517091.1
CDS	205..1881
Translation	MDEGGTPLLPDSLVYQIFLSLGPADVLAAGLVCRQWQAVSRDEFLWREQFYRYYQVARDVPRHPAAMSWYEEFQRLYDTVPCVEVQTLREHTDQVLHLSFSHSGYQFASCSKDCTVKAITTAAPAEQIWSNDLTISLLHSADMRPYNWSYTQFSQFNKDDSLLLASGVFLGPHNSSSGEIAVISLDSFALLSRVRNKPYDVFGCWLTETSLISGNLHRIGDITSCSVLWLNNAFQDVESENVNVVKRLFKIQNLNASTVRTVMVADCSRFDSPDLLLEAGDPATSPCRIFDLGSDNEEVVAGPAPAHAKEGLRHFLDRVLEGRAQPQLSERMLETKVAELLAQGHTKPPERSATGAKSIKQILPHQMTTAGPVLGEGRGSDAFFDALDHVIDIHGHIIGMGLSPDNRYLYVNSRAWPNGAVVADPMQPPPIAEEIDLLVFDLKTMREVRRALRAHRAYTPNDECFFIFLDVSRDFVASGAEDRHGYIWDRHYNICLARLRHEDVVNSVVFSPQEQELLLTASDDATIKAWRSPRTMRVLQAPRPRPRTFFSWLASQRR

Target ORF information:

RefSeq Version	XM_011518789.1
Organism	Homo sapiens(human)
Definition	Homo sapiens F-box and WD repeat domain containing 5 (FBXW5), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011518789.1

ORF Insert Sequence:

ATGGACGAGG GCGGCACGCC CCTGCTCCCC GACAGCCTGG TCTACCAGAT CTTCCTGAGC 
CTGGGCCCGG CCGACGTGCT GGCCGCCGGG CTGGTGTGCC GCCAATGGCA GGCCGTGTCG 
CGGGACGAGT TCCTGTGGAG GGAGCAGTTC TACCGCTACT ACCAGGTGGC CCGCGACGTG 
CCCCGACACC CAGCGGCCAT GTCCTGGTAC GAGGAGTTCC AGCGGCTGTA TGACACGGTG 
CCCTGCGTGG AGGTGCAGAC GCTGCGGGAA CACACAGACC AGGTCCTGCA CCTCAGCTTC 
TCCCATTCCG GGTACCAGTT CGCGTCCTGC TCCAAGGACT GCACTGTGAA GGCGATCACT 
ACAGCCGCCC CTGCCGAACA GATCTGGAGC AACGACCTGA CCATCTCGCT GCTGCACAGC 
GCGGACATGC GGCCCTACAA CTGGAGCTAC ACCCAGTTCT CCCAGTTCAA CAAGGACGAC 
TCGCTACTGC TGGCCTCGGG GGTGTTCCTG GGGCCGCACA ACTCCTCATC CGGCGAGATT 
GCTGTCATCA GCCTAGACTC CTTCGCGCTG CTGTCCCGCG TGCGGAACAA GCCCTATGAC 
GTGTTTGGCT GTTGGCTCAC CGAGACCAGC CTCATCTCGG GGAACCTGCA CCGCATCGGA 
GATATCACCT CCTGCTCGGT GCTGTGGCTC AACAATGCCT TCCAGGATGT GGAGTCAGAG 
AACGTCAACG TGGTGAAGCG GCTGTTCAAG ATCCAGAACC TCAATGCCAG CACCGTCCGC 
ACGGTGATGG TGGCCGACTG CAGCCGCTTC GACAGCCCTG ACCTGCTGCT GGAAGCCGGT 
GACCCGGCCA CGTCCCCCTG CCGCATCTTT GACCTGGGCA GCGACAACGA GGAGGTGGTG 
GCTGGCCCGG CCCCCGCCCA CGCCAAGGAG GGCTTGCGGC ACTTTCTGGA CCGCGTGCTG 
GAGGGGCGGG CGCAGCCACA GCTGTCGGAG CGCATGCTAG AGACCAAGGT GGCCGAGCTG 
CTGGCCCAGG GCCACACCAA GCCACCCGAG CGCAGTGCCA CAGGCGCCAA GAGCATCAAG 
CAGATCCTGC CACACCAGAT GACCACGGCA GGGCCCGTGC TGGGTGAGGG CCGGGGCTCC 
GATGCCTTCT TCGACGCGCT GGACCACGTC ATAGACATAC ACGGACACAT CATCGGCATG 
GGCCTGTCGC CCGACAACAG GTACCTGTAC GTGAACAGCC GCGCCTGGCC CAACGGTGCG 
GTGGTGGCCG ACCCCATGCA GCCGCCACCA ATCGCGGAGG AGATTGACCT GCTGGTGTTC 
GACCTCAAGA CCATGCGGGA GGTGAGGCGG GCTCTGCGTG CGCACCGCGC CTACACGCCC 
AACGACGAGT GCTTCTTCAT CTTCCTGGAC GTCAGCAGGG ACTTCGTGGC CAGCGGGGCG 
GAGGACCGGC ACGGCTACAT CTGGGACCGC CACTACAACA TCTGTCTGGC CAGGCTGCGG 
CACGAGGATG TGGTCAACTC AGTGGTCTTC AGTCCCCAGG AGCAGGAGCT GCTGCTCACG 
GCCAGCGACG ACGCCACCAT CAAAGCCTGG CGCTCCCCAC GCACCATGCG CGTCCTCCAG 
GCACCTCGCC CACGGCCTCG CACCTTCTTC TCCTGGCTTG CCAGCCAGAG GCGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FBXW5 ( XM_017014812.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016870301.1 Homo sapiens F-box and WD repeat domain containing 5 (FBXW5), transcript variant X3, mRNA.

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CloneID	OHu98696
Clone ID Related Accession (Same CDS sequence)	XM_017014812.1 , XM_017014812.2
Accession Version	XM_017014812.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1647bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	F-box/WD repeat-containing protein 5 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000009.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACGAGG GCGGCACGCC CCTGCTCCCC GACAGCCTGG TCTACCAGAT CTTCCTGAGC 
CTGGGCCCGG CCGACGTGCT GGCCGCCGGG CTGGTGTGCC GCCAATGGCA GGCCGTGTCG 
CGGGACGAGT TCCTGTGGAG GGAGCAGTTC TACCGCTACT ACCAGGTGGC CCGCGACGTG 
CCCCGACACC CAGCGGCCAT GTCCTGGTAC GAGGAGTTCC AGCGGCTGTA TGACACGGTG 
CCCTGCGTGG AGGTGCAGAC GCTGCGGGAA CACACAGACC AGGTCCTGCA CCTCAGCTTC 
TCCCATTCCG GGTACCAGTT CGCGTCCTGC TCCAAGGACT GCACTGTGAA GATCTGGAGC 
AACGACCTGA CCATCTCGCT GCTGCACAGC GCGGACATGC GGCCCTACAA CTGGAGCTAC 
ACCCAGTTCT CCCAGTTCAA CAAGGACGAC TCGCTACTGC TGGCCTCGGG GGTGTTCCTG 
GGGCCGCACA ACTCCTCATC CGGCGAGATT GCTGTCATCA GCCTAGACTC CTTCGCGCTG 
CTGTCCCGCG TGCGGAACAA GCCCTATGAC GTGTTTGGCT GTTGGCTCAC CGAGACCAGC 
CTCATCTCGG GGAACCTGCA CCGCATCGGA GATATCACCT CCTGCTCGGT GCTGTGGCTC 
AACAATGCCT TCCAGGATGT GGAGTCAGAG AACGTCAACG TGGTGAAGCG GCTGTTCAAG 
ATCCAGAACC TCAATGCCAG CACCGTCCGC ACGGTGATGG TGGCCGACTG CAGCCGCTTC 
GACAGCCCTG ACCTGCTGCT GGAAGCCGGT GACCCGGCCA CGTCCCCCTG CCGCATCTTT 
GACCTGGGCA GCGACAACGA GGAGGTGGTG GCTGGCCCGG CCCCCGCCCA CGCCAAGGAG 
GGCTTGCGGC ACTTTCTGGA CCGCGTGCTG GAGGGGCGGG CGCAGCCACA GCTGTCGGAG 
CGCATGCTAG AGACCAAGGT GGCCGAGCTG CTGGCCCAGG GCCACACCAA GCCACCCGAG 
CGCAGTGCCA CAGGCGCCAA GAGCATCAAG CAGATCCTGC CACACCAGAT GACCACGGCA 
GGGCCCGTGC TGGGTGAGGG CCGGGGCTCC GATGCCTTCT TCGACGCGCT GGACCACGTC 
ATAGACATAC ACGGACACAT CATCGGCATG GGCCTGTCGC CCGACAACAG GTACCTGTAC 
GTGAACAGCC GCGCCTGGCC CAACGGTGCG GTGGTGGCCG ACCCCATGCA GCCGCCACCA 
ATCGCGGAGG AGATTGACCT GCTGGTGTTC GACCTCAAGA CCATGCGGGA GGTGAGGCGG 
GCTCTGCGTG CGCACCGCGC CTACACGCCC AACGACGAGT GCTTCTTCAT CTTCCTGGAC 
GTCAGCAGGG ACTTCGTGGC CAGCGGGGCG GAGGACCGGC ACGGCTACAT CTGGGACCGC 
CACTACAACA TCTGTCTGGC CAGGCTGCGG CACGAGGATG TGGTCAACTC AGTGGTCTTC 
AGTCCCCAGG AGCAGGAGCT GCTGCTCACG GCCAGCGACG ACGCCACCAT CAAAGCCTGG 
CGCTCCCCAC GCACCATGCG CGTCCTCCAG GCACCTCGCC CACGGCCTCG CACCTTCTTC 
TCCTGGCTTG CCAGCCAGAG GCGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016870301.1
CDS	205..1851
Translation	MDEGGTPLLPDSLVYQIFLSLGPADVLAAGLVCRQWQAVSRDEFLWREQFYRYYQVARDVPRHPAAMSWYEEFQRLYDTVPCVEVQTLREHTDQVLHLSFSHSGYQFASCSKDCTVKIWSNDLTISLLHSADMRPYNWSYTQFSQFNKDDSLLLASGVFLGPHNSSSGEIAVISLDSFALLSRVRNKPYDVFGCWLTETSLISGNLHRIGDITSCSVLWLNNAFQDVESENVNVVKRLFKIQNLNASTVRTVMVADCSRFDSPDLLLEAGDPATSPCRIFDLGSDNEEVVAGPAPAHAKEGLRHFLDRVLEGRAQPQLSERMLETKVAELLAQGHTKPPERSATGAKSIKQILPHQMTTAGPVLGEGRGSDAFFDALDHVIDIHGHIIGMGLSPDNRYLYVNSRAWPNGAVVADPMQPPPIAEEIDLLVFDLKTMREVRRALRAHRAYTPNDECFFIFLDVSRDFVASGAEDRHGYIWDRHYNICLARLRHEDVVNSVVFSPQEQELLLTASDDATIKAWRSPRTMRVLQAPRPRPRTFFSWLASQRR

Target ORF information:

RefSeq Version	XM_017014812.1
Organism	Homo sapiens(human)
Definition	Homo sapiens F-box and WD repeat domain containing 5 (FBXW5), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017014812.1

ORF Insert Sequence:

ATGGACGAGG GCGGCACGCC CCTGCTCCCC GACAGCCTGG TCTACCAGAT CTTCCTGAGC 
CTGGGCCCGG CCGACGTGCT GGCCGCCGGG CTGGTGTGCC GCCAATGGCA GGCCGTGTCG 
CGGGACGAGT TCCTGTGGAG GGAGCAGTTC TACCGCTACT ACCAGGTGGC CCGCGACGTG 
CCCCGACACC CAGCGGCCAT GTCCTGGTAC GAGGAGTTCC AGCGGCTGTA TGACACGGTG 
CCCTGCGTGG AGGTGCAGAC GCTGCGGGAA CACACAGACC AGGTCCTGCA CCTCAGCTTC 
TCCCATTCCG GGTACCAGTT CGCGTCCTGC TCCAAGGACT GCACTGTGAA GATCTGGAGC 
AACGACCTGA CCATCTCGCT GCTGCACAGC GCGGACATGC GGCCCTACAA CTGGAGCTAC 
ACCCAGTTCT CCCAGTTCAA CAAGGACGAC TCGCTACTGC TGGCCTCGGG GGTGTTCCTG 
GGGCCGCACA ACTCCTCATC CGGCGAGATT GCTGTCATCA GCCTAGACTC CTTCGCGCTG 
CTGTCCCGCG TGCGGAACAA GCCCTATGAC GTGTTTGGCT GTTGGCTCAC CGAGACCAGC 
CTCATCTCGG GGAACCTGCA CCGCATCGGA GATATCACCT CCTGCTCGGT GCTGTGGCTC 
AACAATGCCT TCCAGGATGT GGAGTCAGAG AACGTCAACG TGGTGAAGCG GCTGTTCAAG 
ATCCAGAACC TCAATGCCAG CACCGTCCGC ACGGTGATGG TGGCCGACTG CAGCCGCTTC 
GACAGCCCTG ACCTGCTGCT GGAAGCCGGT GACCCGGCCA CGTCCCCCTG CCGCATCTTT 
GACCTGGGCA GCGACAACGA GGAGGTGGTG GCTGGCCCGG CCCCCGCCCA CGCCAAGGAG 
GGCTTGCGGC ACTTTCTGGA CCGCGTGCTG GAGGGGCGGG CGCAGCCACA GCTGTCGGAG 
CGCATGCTAG AGACCAAGGT GGCCGAGCTG CTGGCCCAGG GCCACACCAA GCCACCCGAG 
CGCAGTGCCA CAGGCGCCAA GAGCATCAAG CAGATCCTGC CACACCAGAT GACCACGGCA 
GGGCCCGTGC TGGGTGAGGG CCGGGGCTCC GATGCCTTCT TCGACGCGCT GGACCACGTC 
ATAGACATAC ACGGACACAT CATCGGCATG GGCCTGTCGC CCGACAACAG GTACCTGTAC 
GTGAACAGCC GCGCCTGGCC CAACGGTGCG GTGGTGGCCG ACCCCATGCA GCCGCCACCA 
ATCGCGGAGG AGATTGACCT GCTGGTGTTC GACCTCAAGA CCATGCGGGA GGTGAGGCGG 
GCTCTGCGTG CGCACCGCGC CTACACGCCC AACGACGAGT GCTTCTTCAT CTTCCTGGAC 
GTCAGCAGGG ACTTCGTGGC CAGCGGGGCG GAGGACCGGC ACGGCTACAT CTGGGACCGC 
CACTACAACA TCTGTCTGGC CAGGCTGCGG CACGAGGATG TGGTCAACTC AGTGGTCTTC 
AGTCCCCAGG AGCAGGAGCT GCTGCTCACG GCCAGCGACG ACGCCACCAT CAAAGCCTGG 
CGCTCCCCAC GCACCATGCG CGTCCTCCAG GCACCTCGCC CACGGCCTCG CACCTTCTTC 
TCCTGGCTTG CCAGCCAGAG GCGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FBXW5 ( XM_017014812.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_016870301.1 Homo sapiens F-box and WD repeat domain containing 5 (FBXW5), transcript variant X3, mRNA.

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CloneID	OHu98696
Clone ID Related Accession (Same CDS sequence)	XM_017014812.1 , XM_017014812.2
Accession Version	XM_017014812.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1647bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	F-box/WD repeat-containing protein 5 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000009.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017014812.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACGAGG GCGGCACGCC CCTGCTCCCC GACAGCCTGG TCTACCAGAT CTTCCTGAGC 
CTGGGCCCGG CCGACGTGCT GGCCGCCGGG CTGGTGTGCC GCCAATGGCA GGCCGTGTCG 
CGGGACGAGT TCCTGTGGAG GGAGCAGTTC TACCGCTACT ACCAGGTGGC CCGCGACGTG 
CCCCGACACC CAGCGGCCAT GTCCTGGTAC GAGGAGTTCC AGCGGCTGTA TGACACGGTG 
CCCTGCGTGG AGGTGCAGAC GCTGCGGGAA CACACAGACC AGGTCCTGCA CCTCAGCTTC 
TCCCATTCCG GGTACCAGTT CGCGTCCTGC TCCAAGGACT GCACTGTGAA GATCTGGAGC 
AACGACCTGA CCATCTCGCT GCTGCACAGC GCGGACATGC GGCCCTACAA CTGGAGCTAC 
ACCCAGTTCT CCCAGTTCAA CAAGGACGAC TCGCTACTGC TGGCCTCGGG GGTGTTCCTG 
GGGCCGCACA ACTCCTCATC CGGCGAGATT GCTGTCATCA GCCTAGACTC CTTCGCGCTG 
CTGTCCCGCG TGCGGAACAA GCCCTATGAC GTGTTTGGCT GTTGGCTCAC CGAGACCAGC 
CTCATCTCGG GGAACCTGCA CCGCATCGGA GATATCACCT CCTGCTCGGT GCTGTGGCTC 
AACAATGCCT TCCAGGATGT GGAGTCAGAG AACGTCAACG TGGTGAAGCG GCTGTTCAAG 
ATCCAGAACC TCAATGCCAG CACCGTCCGC ACGGTGATGG TGGCCGACTG CAGCCGCTTC 
GACAGCCCTG ACCTGCTGCT GGAAGCCGGT GACCCGGCCA CGTCCCCCTG CCGCATCTTT 
GACCTGGGCA GCGACAACGA GGAGGTGGTG GCTGGCCCGG CCCCCGCCCA CGCCAAGGAG 
GGCTTGCGGC ACTTTCTGGA CCGCGTGCTG GAGGGGCGGG CGCAGCCACA GCTGTCGGAG 
CGCATGCTAG AGACCAAGGT GGCCGAGCTG CTGGCCCAGG GCCACACCAA GCCACCCGAG 
CGCAGTGCCA CAGGCGCCAA GAGCATCAAG CAGATCCTGC CACACCAGAT GACCACGGCA 
GGGCCCGTGC TGGGTGAGGG CCGGGGCTCC GATGCCTTCT TCGACGCGCT GGACCACGTC 
ATAGACATAC ACGGACACAT CATCGGCATG GGCCTGTCGC CCGACAACAG GTACCTGTAC 
GTGAACAGCC GCGCCTGGCC CAACGGTGCG GTGGTGGCCG ACCCCATGCA GCCGCCACCA 
ATCGCGGAGG AGATTGACCT GCTGGTGTTC GACCTCAAGA CCATGCGGGA GGTGAGGCGG 
GCTCTGCGTG CGCACCGCGC CTACACGCCC AACGACGAGT GCTTCTTCAT CTTCCTGGAC 
GTCAGCAGGG ACTTCGTGGC CAGCGGGGCG GAGGACCGGC ACGGCTACAT CTGGGACCGC 
CACTACAACA TCTGTCTGGC CAGGCTGCGG CACGAGGATG TGGTCAACTC AGTGGTCTTC 
AGTCCCCAGG AGCAGGAGCT GCTGCTCACG GCCAGCGACG ACGCCACCAT CAAAGCCTGG 
CGCTCCCCAC GCACCATGCG CGTCCTCCAG GCACCTCGCC CACGGCCTCG CACCTTCTTC 
TCCTGGCTTG CCAGCCAGAG GCGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016870301.1
CDS	60..1706
Translation	MDEGGTPLLPDSLVYQIFLSLGPADVLAAGLVCRQWQAVSRDEFLWREQFYRYYQVARDVPRHPAAMSWYEEFQRLYDTVPCVEVQTLREHTDQVLHLSFSHSGYQFASCSKDCTVKIWSNDLTISLLHSADMRPYNWSYTQFSQFNKDDSLLLASGVFLGPHNSSSGEIAVISLDSFALLSRVRNKPYDVFGCWLTETSLISGNLHRIGDITSCSVLWLNNAFQDVESENVNVVKRLFKIQNLNASTVRTVMVADCSRFDSPDLLLEAGDPATSPCRIFDLGSDNEEVVAGPAPAHAKEGLRHFLDRVLEGRAQPQLSERMLETKVAELLAQGHTKPPERSATGAKSIKQILPHQMTTAGPVLGEGRGSDAFFDALDHVIDIHGHIIGMGLSPDNRYLYVNSRAWPNGAVVADPMQPPPIAEEIDLLVFDLKTMREVRRALRAHRAYTPNDECFFIFLDVSRDFVASGAEDRHGYIWDRHYNICLARLRHEDVVNSVVFSPQEQELLLTASDDATIKAWRSPRTMRVLQAPRPRPRTFFSWLASQRR

Target ORF information:

RefSeq Version	XM_017014812.2
Organism	Homo sapiens(human)
Definition	Homo sapiens F-box and WD repeat domain containing 5 (FBXW5), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017014812.2

ORF Insert Sequence:

ATGGACGAGG GCGGCACGCC CCTGCTCCCC GACAGCCTGG TCTACCAGAT CTTCCTGAGC 
CTGGGCCCGG CCGACGTGCT GGCCGCCGGG CTGGTGTGCC GCCAATGGCA GGCCGTGTCG 
CGGGACGAGT TCCTGTGGAG GGAGCAGTTC TACCGCTACT ACCAGGTGGC CCGCGACGTG 
CCCCGACACC CAGCGGCCAT GTCCTGGTAC GAGGAGTTCC AGCGGCTGTA TGACACGGTG 
CCCTGCGTGG AGGTGCAGAC GCTGCGGGAA CACACAGACC AGGTCCTGCA CCTCAGCTTC 
TCCCATTCCG GGTACCAGTT CGCGTCCTGC TCCAAGGACT GCACTGTGAA GATCTGGAGC 
AACGACCTGA CCATCTCGCT GCTGCACAGC GCGGACATGC GGCCCTACAA CTGGAGCTAC 
ACCCAGTTCT CCCAGTTCAA CAAGGACGAC TCGCTACTGC TGGCCTCGGG GGTGTTCCTG 
GGGCCGCACA ACTCCTCATC CGGCGAGATT GCTGTCATCA GCCTAGACTC CTTCGCGCTG 
CTGTCCCGCG TGCGGAACAA GCCCTATGAC GTGTTTGGCT GTTGGCTCAC CGAGACCAGC 
CTCATCTCGG GGAACCTGCA CCGCATCGGA GATATCACCT CCTGCTCGGT GCTGTGGCTC 
AACAATGCCT TCCAGGATGT GGAGTCAGAG AACGTCAACG TGGTGAAGCG GCTGTTCAAG 
ATCCAGAACC TCAATGCCAG CACCGTCCGC ACGGTGATGG TGGCCGACTG CAGCCGCTTC 
GACAGCCCTG ACCTGCTGCT GGAAGCCGGT GACCCGGCCA CGTCCCCCTG CCGCATCTTT 
GACCTGGGCA GCGACAACGA GGAGGTGGTG GCTGGCCCGG CCCCCGCCCA CGCCAAGGAG 
GGCTTGCGGC ACTTTCTGGA CCGCGTGCTG GAGGGGCGGG CGCAGCCACA GCTGTCGGAG 
CGCATGCTAG AGACCAAGGT GGCCGAGCTG CTGGCCCAGG GCCACACCAA GCCACCCGAG 
CGCAGTGCCA CAGGCGCCAA GAGCATCAAG CAGATCCTGC CACACCAGAT GACCACGGCA 
GGGCCCGTGC TGGGTGAGGG CCGGGGCTCC GATGCCTTCT TCGACGCGCT GGACCACGTC 
ATAGACATAC ACGGACACAT CATCGGCATG GGCCTGTCGC CCGACAACAG GTACCTGTAC 
GTGAACAGCC GCGCCTGGCC CAACGGTGCG GTGGTGGCCG ACCCCATGCA GCCGCCACCA 
ATCGCGGAGG AGATTGACCT GCTGGTGTTC GACCTCAAGA CCATGCGGGA GGTGAGGCGG 
GCTCTGCGTG CGCACCGCGC CTACACGCCC AACGACGAGT GCTTCTTCAT CTTCCTGGAC 
GTCAGCAGGG ACTTCGTGGC CAGCGGGGCG GAGGACCGGC ACGGCTACAT CTGGGACCGC 
CACTACAACA TCTGTCTGGC CAGGCTGCGG CACGAGGATG TGGTCAACTC AGTGGTCTTC 
AGTCCCCAGG AGCAGGAGCT GCTGCTCACG GCCAGCGACG ACGCCACCAT CAAAGCCTGG 
CGCTCCCCAC GCACCATGCG CGTCCTCCAG GCACCTCGCC CACGGCCTCG CACCTTCTTC 
TCCTGGCTTG CCAGCCAGAG GCGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A High-Density Map for Navigating the Human Polycomb Complexome.
Cell reports17(2)583-595(2016 10)
Hauri S,Comoglio F,Seimiya M,Gerstung M,Glatter T,Hansen K,Aebersold R,Paro R,Gstaiger M,Beisel C

Tnfaip8?l1/Oxi-? binds to FBXW5, increasing autophagy through activation of TSC2 in a Parkinson's disease model.
Journal of neurochemistry129(3)527-38(2014 May)
Ha JY,Kim JS,Kang YH,Bok E,Kim YS,Son JH

CRL4A-FBXW5-mediated degradation of DLC1 Rho GTPase-activating protein tumor suppressor promotes non-small cell lung cancer cell growth.
Proceedings of the National Academy of Sciences of the United States of America110(42)16868-73(2013 Oct)
Kim TY,Jackson S,Xiong Y,Whitsett TG,Lobello JR,Weiss GJ,Tran NL,Bang YJ,Der CJ

SCFFbxw5 mediates transient degradation of actin remodeller Eps8 to allow proper mitotic progression.
Nature cell biology15(2)179-88(2013 Feb)
Werner A,Disanza A,Reifenberger N,Habeck G,Becker J,Calabrese M,Urlaub H,Lorenz H,Schulman B,Scita G,Melchior F

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FBXW5 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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