FBXO42 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	FBXO42
Entrez Gene ID	54455
Full Name	F-box protein 42
Synonyms	Fbx42,JFK
General protein information	Preferred Names F-box protein 42 Names F-box only protein 42 just one F-box and Kelch domain-containing protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1p36.13
Summary	Members of the F-box protein family, such as FBXO42, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (SKP1A; MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Dec 2010].
Disorder MIM:	609109

mRNA and Protein(s)

mRNA	Protein	Name
NM_018994.3	NP_061867.1	F-box only protein 42
NM_018994.2	NP_061867.1	F-box only protein 42
XM_006710698.3	XP_006710761.1	F-box only protein 42 isoform X1
XM_017001503.1	XP_016856992.1	F-box only protein 42 isoform X2
XM_017001502.1	XP_016856991.1	F-box only protein 42 isoform X2

Pathways from BioSystems

Homologies

	FBXO42	XP_001086223.2
Danio rerio (zebrafish)	fbxo42	NP_997904.1
Canis lupus familiaris (dog)	FBXO42	XP_852026.1
Bos taurus (cattle)	FBXO42	XP_005203431.1
Mus musculus (house mouse)	Fbxo42	NP_766106.2
Xenopus tropicalis (tropical clawed frog)	fbxo42	XP_002943157.2
Homo sapiens (human)	FBXO42	NP_061867.1
Rattus norvegicus (Norway rat)	Fbxo42	NP_001102161.1
Pan troglodytes (chimpanzee)	FBXO42	XP_513066.2
Gallus gallus (chicken)	FBXO42	XP_417619.3

Gene Ontology
Bibliography

Related articles in PubMed

SCF(JFK) is a bona fide E3 ligase for ING4 and a potent promoter of the angiogenesis and metastasis of breast cancer.
Yan R, He L, Li Z, Han X, Liang J, Si W, Chen Z, Li L, Xie G, Li W, Wang P, Lei L, Zhang H, Pei F, Cao D, Sun L, Shang Y
Genes & development29(6)672-85(2015 Mar)

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.
Li X, Wang W, Wang J, Malovannaya A, Xi Y, Li W, Guerra R, Hawke DH, Qin J, Chen J
Molecular systems biology11(1)775(2015 Jan)

Genetic analysis of the FBXO42 gene in Chinese Han patients with Parkinson's disease.
Gao K, Deng X, Zheng W, Song Z, Zhu A, Xiu X, Deng H
BMC neurology13125(2013 Sep)

Substrate phosphorylation and feedback regulation in JFK-promoted p53 destabilization.
Sun L, Shi L, Wang F, Huangyang P, Si W, Yang J, Yao Z, Shang Y
The Journal of biological chemistry286(6)4226-35(2011 Feb)

JFK, a Kelch domain-containing F-box protein, links the SCF complex to p53 regulation.
Sun L, Shi L, Li W, Yu W, Liang J, Zhang H, Yang X, Wang Y, Li R, Yao X, Yi X, Shang Y
Proceedings of the National Academy of Sciences of the United States of America106(25)10195-200(2009 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

SCF(JFK) as a bona fide E3 ligase for ING4 and unraveled the JFK-ING4-NF-kappaB axis as an important player in the development and progression of breast cancer
Title: SCF(JFK) is a bona fide E3 ligase for ING4 and a potent promoter of the angiogenesis and metastasis of breast cancer.

The findings of this study suggest that a haplotype of the FBXO42 gene might be associated with a higher susceptibility to PD.
Title: Genetic analysis of the FBXO42 gene in Chinese Han patients with Parkinson's disease.

Substrate phosphorylation and feedback regulation in JFK-promoted p53 destabilization.
Title: Substrate phosphorylation and feedback regulation in JFK-promoted p53 destabilization.

JFK promotes p53 turnover through assembly of an SCF (Skp1-Cul1-F-box) complex, revealing a pathway for the control of p53 degradation and providing a link between the SCF complex and p53 regulation.
Title: JFK, a Kelch domain-containing F-box protein, links the SCF complex to p53 regulation.

The following FBXO42 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FBXO42 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu33515	NM_018994.3 Latest version!	Homo sapiens F-box protein 42 (FBXO42), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
OHu90127	XM_017001503.1 Latest version!	Homo sapiens F-box protein 42 (FBXO42), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu90127	XM_017001502.1 Latest version!	Homo sapiens F-box protein 42 (FBXO42), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu33515	XM_006710698.3 Latest version!	Homo sapiens F-box protein 42 (FBXO42), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$265.30 $379.00
View Old Accession Versions >>
OHu33515	NM_018994.2	Homo sapiens F-box protein 42 (FBXO42), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

FBXO42 ( NM_018994.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_061867.1 Homo sapiens F-box protein 42 (FBXO42), mRNA.

Price & Availability↑

CloneID	OHu33515
Clone ID Related Accession (Same CDS sequence)	NM_018994.3 , NM_018994.2 , XM_006710698.3
Accession Version	NM_018994.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2154bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-26
Organism	Homo sapiens(human)
Product	F-box only protein 42
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA488838.1, HY007337.1, BC063864.1, AB037753.1 and AW449773.1. On Nov 23, 2018 this sequence version replaced NM_018994.2. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.185547.1, SRR1660803.190047.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144333, SAMEA2467144 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000375592.8/ ENSP00000364742.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCCAGCT CCTCGGACAG TGAAGATGAC AGTTTCATGG CTGTGGACCA GGAAGAAACT 
GTGCTGGAAG GGACAATGGA TCAAGATGAG GAGCCCCACC CAGTATTGGA GGCTGAGGAG 
ACTAGACATA ATAGGTCCAT GTCGGAGCTG CCAGAAGAGG TTTTGGAGTA TATCCTGTCC 
TTTCTCTCAC CGTATCAGGA ACACAAAACT GCGGCCCTTG TCTGCAAACA GTGGTATCGA 
CTTATCAAAG GTGTAGCCCA TCAGTGTTAT CATGGTTTCA TGAAGGCTGT CCAGGAAGGA 
AACATTCAGT GGGAGAGCCG TACCTATCCT TATCCTGGAA CCCCAATCAC TCAGCGCTTC 
TCGCACAGTG CATGCTATTA TGATGCTAAT CAGTCTATGT ATGTGTTTGG AGGCTGTACC 
CAGAGCAGCT GCAATGCTGC TTTCAATGAC CTCTGGAGAC TTGACCTAAA CAGCAAAGAG 
TGGATCCGAC CTTTGGCTTC AGGGTCCTAT CCTTCCCCCA AAGCTGGAGC AACTCTGGTC 
GTGTACAAGG ACTTGCTAGT GCTGTTTGGT GGCTGGACGC GGCCAAGCCC TTATCCCCTA 
CACCAGCCAG AGAGATTCTT TGATGAAATA CACACTTACT CACCCTCTAA AAATTGGTGG 
AACTGCATTG TGACAACCCA TGGGCCACCT CCCATGGCTG GCCACTCCTC CTGTGTGATA 
GATGATAAAA TGATTGTCTT TGGTGGCTCT TTAGGATCCC GGCAAATGAG CAATGATGTC 
TGGGTCCTTG ACCTTGAGCA GTGGGCGTGG TCCAAGCCGA ACATCTCTGG CCCCAGTCCT 
CATCCTCGAG GTGGCCAATC TCAGATTGTC ATAGATGATG CAACTATCTT AATCCTCGGA 
GGGTGTGGCG GTCCCAATGC TCTATTCAAG GATGCTTGGT TGTTGCACAT GCATTCTGGT 
CCTTGGGCCT GGCAGCCACT CAAGGTAGAA AATGAAGAGC ATGGGGCCCC AGAACTGTGG 
TGCCATCCAG CTTGCCGGGT GGGACAGTGT GTGGTGGTCT TCAGCCAGGC TCCTAGTGGG 
AGAGCCCCAC TCAGCCCCAG TTTGAACTCT CGCCCATCAC CTATCAGTGC CACTCCTCCA 
GCTCTCGTTC CTGAAACCCG AGAGTACCGC TCTCAGTCTC CAGTAAGAAG CATGGATGAA 
GCTCCTTGTG TTAACGGCCG CTGGGGAACA CTGAGACCCA GGGCTCAAAG GCAGACTCCT 
TCAGGTTCCC GGGAAGGGAG CCTTTCCCCA GCCAGAGGAG ACGGCTCTCC TATCCTCAAT 
GGTGGGAGTT TGTCTCCAGG AACGGCAGCT GTGGGTGGCT CTTCTTTGGA CAGTCCTGTA 
CAGGCCATAT CTCCAAGTAC TCCATCTGCT CCTGAAGGAT ACGACCTGAA AATAGGACTT 
TCTTTGGCCC CCCGACGAGG ATCACTACCA GATCAGAAAG ATCTGAGATT AGGATCCATA 
GATCTGAATT GGGATCTGAA ACCCGCTTCC AGTAGTAATC CCATGGATGG CATGGACAAT 
AGGACAGTTG GGGGAAGTAT GAGACACCCT CCTGAACAGA CAAATGGTGT GCATACCCCA 
CCTCACGTGG CCAGTGCCCT TGCAGGGGCC GTCTCCCCAG GTGCCCTGCG TCGGAGTCTG 
GAAGCCATCA AAGCGATGTC CTCCAAAGGC CCCTCGGCCT CTGCAGCACT AAGTCCTCCT 
CTTGGGTCTT CTCCAGGCTC TCCTGGGAGC CAGAGTTTGA GCAGTGGAGA AACAGTGCCC 
ATCCCTCGCC CAGGGCCTGC CCAAGGAGAT GGACATTCCT TACCTCCCAT TGCTCGCCGC 
CTGGGCCACC ACCCTCCACA GTCCCTAAAT GTTGGCAAAC CCCTATACCA GAGTATGAAC 
TGCAAGCCCA TGCAGATGTA CGTGCTGGAC ATTAAAGACA CCAAGGAGAA GGGGCGGGTC 
AAATGGAAAG TATTTAATAG CAGTTCTGTG GTTGGACCTC CTGAAACCAG CCTGCATACC 
GTGGTACAAG GCAGGGGTGA ACTCATCATA TTTGGAGGAC TCATGGACAA GAAACAGAAT 
GTGAAGTACT ATCCAAAAAC AAACGCCTTG TACTTTGTAC GAGCAAAGAG ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_061867.1
CDS	244..2397
Translation	MASSSDSEDDSFMAVDQEETVLEGTMDQDEEPHPVLEAEETRHNRSMSELPEEVLEYILSFLSPYQEHKTAALVCKQWYRLIKGVAHQCYHGFMKAVQEGNIQWESRTYPYPGTPITQRFSHSACYYDANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASGSYPSPKAGATLVVYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTHGPPPMAGHSSCVIDDKMIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPRGGQSQIVIDDATILILGGCGGPNALFKDAWLLHMHSGPWAWQPLKVENEEHGAPELWCHPACRVGQCVVVFSQAPSGRAPLSPSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQRQTPSGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRHPPEQTNGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGSSPGSPGSQSLSSGETVPIPRPGPAQGDGHSLPPIARRLGHHPPQSLNVGKPLYQSMNCKPMQMYVLDIKDTKEKGRVKWKVFNSSSVVGPPETSLHTVVQGRGELIIFGGLMDKKQNVKYYPKTNALYFVRAKR

Target ORF information:

RefSeq Version	NM_018994.3
Organism	Homo sapiens(human)
Definition	Homo sapiens F-box protein 42 (FBXO42), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018994.3

ORF Insert Sequence:

ATGGCCAGCT CCTCGGACAG TGAAGATGAC AGTTTCATGG CTGTGGACCA GGAAGAAACT 
GTGCTGGAAG GGACAATGGA TCAAGATGAG GAGCCCCACC CAGTATTGGA GGCTGAGGAG 
ACTAGACATA ATAGGTCCAT GTCGGAGCTG CCAGAAGAGG TTTTGGAGTA TATCCTGTCC 
TTTCTCTCAC CGTATCAGGA ACACAAAACT GCGGCCCTTG TCTGCAAACA GTGGTATCGA 
CTTATCAAAG GTGTAGCCCA TCAGTGTTAT CATGGTTTCA TGAAGGCTGT CCAGGAAGGA 
AACATTCAGT GGGAGAGCCG TACCTATCCT TATCCTGGAA CCCCAATCAC TCAGCGCTTC 
TCGCACAGTG CATGCTATTA TGATGCTAAT CAGTCTATGT ATGTGTTTGG AGGCTGTACC 
CAGAGCAGCT GCAATGCTGC TTTCAATGAC CTCTGGAGAC TTGACCTAAA CAGCAAAGAG 
TGGATCCGAC CTTTGGCTTC AGGGTCCTAT CCTTCCCCCA AAGCTGGAGC AACTCTGGTC 
GTGTACAAGG ACTTGCTAGT GCTGTTTGGT GGCTGGACGC GGCCAAGCCC TTATCCCCTA 
CACCAGCCAG AGAGATTCTT TGATGAAATA CACACTTACT CACCCTCTAA AAATTGGTGG 
AACTGCATTG TGACAACCCA TGGGCCACCT CCCATGGCTG GCCACTCCTC CTGTGTGATA 
GATGATAAAA TGATTGTCTT TGGTGGCTCT TTAGGATCCC GGCAAATGAG CAATGATGTC 
TGGGTCCTTG ACCTTGAGCA GTGGGCGTGG TCCAAGCCGA ACATCTCTGG CCCCAGTCCT 
CATCCTCGAG GTGGCCAATC TCAGATTGTC ATAGATGATG CAACTATCTT AATCCTCGGA 
GGGTGTGGCG GTCCCAATGC TCTATTCAAG GATGCTTGGT TGTTGCACAT GCATTCTGGT 
CCTTGGGCCT GGCAGCCACT CAAGGTAGAA AATGAAGAGC ATGGGGCCCC AGAACTGTGG 
TGCCATCCAG CTTGCCGGGT GGGACAGTGT GTGGTGGTCT TCAGCCAGGC TCCTAGTGGG 
AGAGCCCCAC TCAGCCCCAG TTTGAACTCT CGCCCATCAC CTATCAGTGC CACTCCTCCA 
GCTCTCGTTC CTGAAACCCG AGAGTACCGC TCTCAGTCTC CAGTAAGAAG CATGGATGAA 
GCTCCTTGTG TTAACGGCCG CTGGGGAACA CTGAGACCCA GGGCTCAAAG GCAGACTCCT 
TCAGGTTCCC GGGAAGGGAG CCTTTCCCCA GCCAGAGGAG ACGGCTCTCC TATCCTCAAT 
GGTGGGAGTT TGTCTCCAGG AACGGCAGCT GTGGGTGGCT CTTCTTTGGA CAGTCCTGTA 
CAGGCCATAT CTCCAAGTAC TCCATCTGCT CCTGAAGGAT ACGACCTGAA AATAGGACTT 
TCTTTGGCCC CCCGACGAGG ATCACTACCA GATCAGAAAG ATCTGAGATT AGGATCCATA 
GATCTGAATT GGGATCTGAA ACCCGCTTCC AGTAGTAATC CCATGGATGG CATGGACAAT 
AGGACAGTTG GGGGAAGTAT GAGACACCCT CCTGAACAGA CAAATGGTGT GCATACCCCA 
CCTCACGTGG CCAGTGCCCT TGCAGGGGCC GTCTCCCCAG GTGCCCTGCG TCGGAGTCTG 
GAAGCCATCA AAGCGATGTC CTCCAAAGGC CCCTCGGCCT CTGCAGCACT AAGTCCTCCT 
CTTGGGTCTT CTCCAGGCTC TCCTGGGAGC CAGAGTTTGA GCAGTGGAGA AACAGTGCCC 
ATCCCTCGCC CAGGGCCTGC CCAAGGAGAT GGACATTCCT TACCTCCCAT TGCTCGCCGC 
CTGGGCCACC ACCCTCCACA GTCCCTAAAT GTTGGCAAAC CCCTATACCA GAGTATGAAC 
TGCAAGCCCA TGCAGATGTA CGTGCTGGAC ATTAAAGACA CCAAGGAGAA GGGGCGGGTC 
AAATGGAAAG TATTTAATAG CAGTTCTGTG GTTGGACCTC CTGAAACCAG CCTGCATACC 
GTGGTACAAG GCAGGGGTGA ACTCATCATA TTTGGAGGAC TCATGGACAA GAAACAGAAT 
GTGAAGTACT ATCCAAAAAC AAACGCCTTG TACTTTGTAC GAGCAAAGAG ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FBXO42 ( XM_017001503.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016856992.1 Homo sapiens F-box protein 42 (FBXO42), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu90127
Clone ID Related Accession (Same CDS sequence)	XM_017001503.1 , XM_017001502.1
Accession Version	XM_017001503.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1461bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	F-box only protein 42 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGGCC ACTCCTCCTG TGTGATAGAT GATAAAATGA TTGTCTTTGG TGGCTCTTTA 
GGATCCCGGC AAATGAGCAA TGATGTCTGG GTCCTTGACC TTGAGCAGTG GGCGTGGTCC 
AAGCCGAACA TCTCTGGCCC CAGTCCTCAT CCTCGAGGTG GCCAATCTCA GATTGTCATA 
GATGATGCAA CTATCTTAAT CCTCGGAGGG TGTGGCGGTC CCAATGCTCT ATTCAAGGAT 
GCTTGGTTGT TGCACATGCA TTCTGGTCCT TGGGCCTGGC AGCCACTCAA GGTAGAAAAT 
GAAGAGCATG GGGCCCCAGA ACTGTGGTGC CATCCAGCTT GCCGGGTGGG ACAGTGTGTG 
GTGGTCTTCA GCCAGGCTCC TAGTGGGAGA GCCCCACTCA GCCCCAGTTT GAACTCTCGC 
CCATCACCTA TCAGTGCCAC TCCTCCAGCT CTCGTTCCTG AAACCCGAGA GTACCGCTCT 
CAGTCTCCAG TAAGAAGCAT GGATGAAGCT CCTTGTGTTA ACGGCCGCTG GGGAACACTG 
AGACCCAGGG CTCAAAGGCA GACTCCTTCA GGTTCCCGGG AAGGGAGCCT TTCCCCAGCC 
AGAGGAGACG GCTCTCCTAT CCTCAATGGT GGGAGTTTGT CTCCAGGAAC GGCAGCTGTG 
GGTGGCTCTT CTTTGGACAG TCCTGTACAG GCCATATCTC CAAGTACTCC ATCTGCTCCT 
GAAGGATACG ACCTGAAAAT AGGACTTTCT TTGGCCCCCC GACGAGGATC ACTACCAGAT 
CAGAAAGATC TGAGATTAGG ATCCATAGAT CTGAATTGGG ATCTGAAACC CGCTTCCAGT 
AGTAATCCCA TGGATGGCAT GGACAATAGG ACAGTTGGGG GAAGTATGAG ACACCCTCCT 
GAACAGACAA ATGGTGTGCA TACCCCACCT CACGTGGCCA GTGCCCTTGC AGGGGCCGTC 
TCCCCAGGTG CCCTGCGTCG GAGTCTGGAA GCCATCAAAG CGATGTCCTC CAAAGGCCCC 
TCGGCCTCTG CAGCACTAAG TCCTCCTCTT GGGTCTTCTC CAGGCTCTCC TGGGAGCCAG 
AGTTTGAGCA GTGGAGAAAC AGTGCCCATC CCTCGCCCAG GGCCTGCCCA AGGAGATGGA 
CATTCCTTAC CTCCCATTGC TCGCCGCCTG GGCCACCACC CTCCACAGTC CCTAAATGTT 
GGCAAACCCC TATACCAGAG TATGAACTGC AAGCCCATGC AGATGTACGT GCTGGACATT 
AAAGACACCA AGGAGAAGGG GCGGGTCAAA TGGAAAGTAT TTAATAGCAG TTCTGTGGTT 
GGACCTCCTG AAACCAGCCT GCATACCGTG GTACAAGGCA GGGGTGAACT CATCATATTT 
GGAGGACTCA TGGACAAGAA ACAGAATGTG AAGTACTATC CAAAAACAAA CGCCTTGTAC 
TTTGTACGAG CAAAGAGATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016856992.1
CDS	1007..2467
Translation	MAGHSSCVIDDKMIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPRGGQSQIVIDDATILILGGCGGPNALFKDAWLLHMHSGPWAWQPLKVENEEHGAPELWCHPACRVGQCVVVFSQAPSGRAPLSPSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQRQTPSGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRHPPEQTNGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGSSPGSPGSQSLSSGETVPIPRPGPAQGDGHSLPPIARRLGHHPPQSLNVGKPLYQSMNCKPMQMYVLDIKDTKEKGRVKWKVFNSSSVVGPPETSLHTVVQGRGELIIFGGLMDKKQNVKYYPKTNALYFVRAKR

Target ORF information:

RefSeq Version	XM_017001503.1
Organism	Homo sapiens(human)
Definition	Homo sapiens F-box protein 42 (FBXO42), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017001503.1

ORF Insert Sequence:

ATGGCTGGCC ACTCCTCCTG TGTGATAGAT GATAAAATGA TTGTCTTTGG TGGCTCTTTA 
GGATCCCGGC AAATGAGCAA TGATGTCTGG GTCCTTGACC TTGAGCAGTG GGCGTGGTCC 
AAGCCGAACA TCTCTGGCCC CAGTCCTCAT CCTCGAGGTG GCCAATCTCA GATTGTCATA 
GATGATGCAA CTATCTTAAT CCTCGGAGGG TGTGGCGGTC CCAATGCTCT ATTCAAGGAT 
GCTTGGTTGT TGCACATGCA TTCTGGTCCT TGGGCCTGGC AGCCACTCAA GGTAGAAAAT 
GAAGAGCATG GGGCCCCAGA ACTGTGGTGC CATCCAGCTT GCCGGGTGGG ACAGTGTGTG 
GTGGTCTTCA GCCAGGCTCC TAGTGGGAGA GCCCCACTCA GCCCCAGTTT GAACTCTCGC 
CCATCACCTA TCAGTGCCAC TCCTCCAGCT CTCGTTCCTG AAACCCGAGA GTACCGCTCT 
CAGTCTCCAG TAAGAAGCAT GGATGAAGCT CCTTGTGTTA ACGGCCGCTG GGGAACACTG 
AGACCCAGGG CTCAAAGGCA GACTCCTTCA GGTTCCCGGG AAGGGAGCCT TTCCCCAGCC 
AGAGGAGACG GCTCTCCTAT CCTCAATGGT GGGAGTTTGT CTCCAGGAAC GGCAGCTGTG 
GGTGGCTCTT CTTTGGACAG TCCTGTACAG GCCATATCTC CAAGTACTCC ATCTGCTCCT 
GAAGGATACG ACCTGAAAAT AGGACTTTCT TTGGCCCCCC GACGAGGATC ACTACCAGAT 
CAGAAAGATC TGAGATTAGG ATCCATAGAT CTGAATTGGG ATCTGAAACC CGCTTCCAGT 
AGTAATCCCA TGGATGGCAT GGACAATAGG ACAGTTGGGG GAAGTATGAG ACACCCTCCT 
GAACAGACAA ATGGTGTGCA TACCCCACCT CACGTGGCCA GTGCCCTTGC AGGGGCCGTC 
TCCCCAGGTG CCCTGCGTCG GAGTCTGGAA GCCATCAAAG CGATGTCCTC CAAAGGCCCC 
TCGGCCTCTG CAGCACTAAG TCCTCCTCTT GGGTCTTCTC CAGGCTCTCC TGGGAGCCAG 
AGTTTGAGCA GTGGAGAAAC AGTGCCCATC CCTCGCCCAG GGCCTGCCCA AGGAGATGGA 
CATTCCTTAC CTCCCATTGC TCGCCGCCTG GGCCACCACC CTCCACAGTC CCTAAATGTT 
GGCAAACCCC TATACCAGAG TATGAACTGC AAGCCCATGC AGATGTACGT GCTGGACATT 
AAAGACACCA AGGAGAAGGG GCGGGTCAAA TGGAAAGTAT TTAATAGCAG TTCTGTGGTT 
GGACCTCCTG AAACCAGCCT GCATACCGTG GTACAAGGCA GGGGTGAACT CATCATATTT 
GGAGGACTCA TGGACAAGAA ACAGAATGTG AAGTACTATC CAAAAACAAA CGCCTTGTAC 
TTTGTACGAG CAAAGAGATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FBXO42 ( XM_017001502.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016856991.1 Homo sapiens F-box protein 42 (FBXO42), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu90127
Clone ID Related Accession (Same CDS sequence)	XM_017001503.1 , XM_017001502.1
Accession Version	XM_017001502.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1461bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	F-box only protein 42 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGGCC ACTCCTCCTG TGTGATAGAT GATAAAATGA TTGTCTTTGG TGGCTCTTTA 
GGATCCCGGC AAATGAGCAA TGATGTCTGG GTCCTTGACC TTGAGCAGTG GGCGTGGTCC 
AAGCCGAACA TCTCTGGCCC CAGTCCTCAT CCTCGAGGTG GCCAATCTCA GATTGTCATA 
GATGATGCAA CTATCTTAAT CCTCGGAGGG TGTGGCGGTC CCAATGCTCT ATTCAAGGAT 
GCTTGGTTGT TGCACATGCA TTCTGGTCCT TGGGCCTGGC AGCCACTCAA GGTAGAAAAT 
GAAGAGCATG GGGCCCCAGA ACTGTGGTGC CATCCAGCTT GCCGGGTGGG ACAGTGTGTG 
GTGGTCTTCA GCCAGGCTCC TAGTGGGAGA GCCCCACTCA GCCCCAGTTT GAACTCTCGC 
CCATCACCTA TCAGTGCCAC TCCTCCAGCT CTCGTTCCTG AAACCCGAGA GTACCGCTCT 
CAGTCTCCAG TAAGAAGCAT GGATGAAGCT CCTTGTGTTA ACGGCCGCTG GGGAACACTG 
AGACCCAGGG CTCAAAGGCA GACTCCTTCA GGTTCCCGGG AAGGGAGCCT TTCCCCAGCC 
AGAGGAGACG GCTCTCCTAT CCTCAATGGT GGGAGTTTGT CTCCAGGAAC GGCAGCTGTG 
GGTGGCTCTT CTTTGGACAG TCCTGTACAG GCCATATCTC CAAGTACTCC ATCTGCTCCT 
GAAGGATACG ACCTGAAAAT AGGACTTTCT TTGGCCCCCC GACGAGGATC ACTACCAGAT 
CAGAAAGATC TGAGATTAGG ATCCATAGAT CTGAATTGGG ATCTGAAACC CGCTTCCAGT 
AGTAATCCCA TGGATGGCAT GGACAATAGG ACAGTTGGGG GAAGTATGAG ACACCCTCCT 
GAACAGACAA ATGGTGTGCA TACCCCACCT CACGTGGCCA GTGCCCTTGC AGGGGCCGTC 
TCCCCAGGTG CCCTGCGTCG GAGTCTGGAA GCCATCAAAG CGATGTCCTC CAAAGGCCCC 
TCGGCCTCTG CAGCACTAAG TCCTCCTCTT GGGTCTTCTC CAGGCTCTCC TGGGAGCCAG 
AGTTTGAGCA GTGGAGAAAC AGTGCCCATC CCTCGCCCAG GGCCTGCCCA AGGAGATGGA 
CATTCCTTAC CTCCCATTGC TCGCCGCCTG GGCCACCACC CTCCACAGTC CCTAAATGTT 
GGCAAACCCC TATACCAGAG TATGAACTGC AAGCCCATGC AGATGTACGT GCTGGACATT 
AAAGACACCA AGGAGAAGGG GCGGGTCAAA TGGAAAGTAT TTAATAGCAG TTCTGTGGTT 
GGACCTCCTG AAACCAGCCT GCATACCGTG GTACAAGGCA GGGGTGAACT CATCATATTT 
GGAGGACTCA TGGACAAGAA ACAGAATGTG AAGTACTATC CAAAAACAAA CGCCTTGTAC 
TTTGTACGAG CAAAGAGATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016856991.1
CDS	1077..2537
Translation	MAGHSSCVIDDKMIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPRGGQSQIVIDDATILILGGCGGPNALFKDAWLLHMHSGPWAWQPLKVENEEHGAPELWCHPACRVGQCVVVFSQAPSGRAPLSPSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQRQTPSGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRHPPEQTNGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGSSPGSPGSQSLSSGETVPIPRPGPAQGDGHSLPPIARRLGHHPPQSLNVGKPLYQSMNCKPMQMYVLDIKDTKEKGRVKWKVFNSSSVVGPPETSLHTVVQGRGELIIFGGLMDKKQNVKYYPKTNALYFVRAKR

Target ORF information:

RefSeq Version	XM_017001502.1
Organism	Homo sapiens(human)
Definition	Homo sapiens F-box protein 42 (FBXO42), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017001502.1

ORF Insert Sequence:

ATGGCTGGCC ACTCCTCCTG TGTGATAGAT GATAAAATGA TTGTCTTTGG TGGCTCTTTA 
GGATCCCGGC AAATGAGCAA TGATGTCTGG GTCCTTGACC TTGAGCAGTG GGCGTGGTCC 
AAGCCGAACA TCTCTGGCCC CAGTCCTCAT CCTCGAGGTG GCCAATCTCA GATTGTCATA 
GATGATGCAA CTATCTTAAT CCTCGGAGGG TGTGGCGGTC CCAATGCTCT ATTCAAGGAT 
GCTTGGTTGT TGCACATGCA TTCTGGTCCT TGGGCCTGGC AGCCACTCAA GGTAGAAAAT 
GAAGAGCATG GGGCCCCAGA ACTGTGGTGC CATCCAGCTT GCCGGGTGGG ACAGTGTGTG 
GTGGTCTTCA GCCAGGCTCC TAGTGGGAGA GCCCCACTCA GCCCCAGTTT GAACTCTCGC 
CCATCACCTA TCAGTGCCAC TCCTCCAGCT CTCGTTCCTG AAACCCGAGA GTACCGCTCT 
CAGTCTCCAG TAAGAAGCAT GGATGAAGCT CCTTGTGTTA ACGGCCGCTG GGGAACACTG 
AGACCCAGGG CTCAAAGGCA GACTCCTTCA GGTTCCCGGG AAGGGAGCCT TTCCCCAGCC 
AGAGGAGACG GCTCTCCTAT CCTCAATGGT GGGAGTTTGT CTCCAGGAAC GGCAGCTGTG 
GGTGGCTCTT CTTTGGACAG TCCTGTACAG GCCATATCTC CAAGTACTCC ATCTGCTCCT 
GAAGGATACG ACCTGAAAAT AGGACTTTCT TTGGCCCCCC GACGAGGATC ACTACCAGAT 
CAGAAAGATC TGAGATTAGG ATCCATAGAT CTGAATTGGG ATCTGAAACC CGCTTCCAGT 
AGTAATCCCA TGGATGGCAT GGACAATAGG ACAGTTGGGG GAAGTATGAG ACACCCTCCT 
GAACAGACAA ATGGTGTGCA TACCCCACCT CACGTGGCCA GTGCCCTTGC AGGGGCCGTC 
TCCCCAGGTG CCCTGCGTCG GAGTCTGGAA GCCATCAAAG CGATGTCCTC CAAAGGCCCC 
TCGGCCTCTG CAGCACTAAG TCCTCCTCTT GGGTCTTCTC CAGGCTCTCC TGGGAGCCAG 
AGTTTGAGCA GTGGAGAAAC AGTGCCCATC CCTCGCCCAG GGCCTGCCCA AGGAGATGGA 
CATTCCTTAC CTCCCATTGC TCGCCGCCTG GGCCACCACC CTCCACAGTC CCTAAATGTT 
GGCAAACCCC TATACCAGAG TATGAACTGC AAGCCCATGC AGATGTACGT GCTGGACATT 
AAAGACACCA AGGAGAAGGG GCGGGTCAAA TGGAAAGTAT TTAATAGCAG TTCTGTGGTT 
GGACCTCCTG AAACCAGCCT GCATACCGTG GTACAAGGCA GGGGTGAACT CATCATATTT 
GGAGGACTCA TGGACAAGAA ACAGAATGTG AAGTACTATC CAAAAACAAA CGCCTTGTAC 
TTTGTACGAG CAAAGAGATA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FBXO42 ( NM_018994.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_061867.1 Homo sapiens F-box protein 42 (FBXO42), mRNA.

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CloneID	OHu33515
Clone ID Related Accession (Same CDS sequence)	NM_018994.3 , NM_018994.2 , XM_006710698.3
Accession Version	NM_018994.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2154bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	F-box only protein 42
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA488838.1, HY007337.1, BC063864.1, AB037753.1 and AW449773.1. On Dec 14, 2014 this sequence version replaced NM_018994.1. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.23842.1, SRR1660803.185547.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144333, SAMEA2467144 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCAGCT CCTCGGACAG TGAAGATGAC AGTTTCATGG CTGTGGACCA GGAAGAAACT 
GTGCTGGAAG GGACAATGGA TCAAGATGAG GAGCCCCACC CAGTATTGGA GGCTGAGGAG 
ACTAGACATA ATAGGTCCAT GTCGGAGCTG CCAGAAGAGG TTTTGGAGTA TATCCTGTCC 
TTTCTCTCAC CGTATCAGGA ACACAAAACT GCGGCCCTTG TCTGCAAACA GTGGTATCGA 
CTTATCAAAG GTGTAGCCCA TCAGTGTTAT CATGGTTTCA TGAAGGCTGT CCAGGAAGGA 
AACATTCAGT GGGAGAGCCG TACCTATCCT TATCCTGGAA CCCCAATCAC TCAGCGCTTC 
TCGCACAGTG CATGCTATTA TGATGCTAAT CAGTCTATGT ATGTGTTTGG AGGCTGTACC 
CAGAGCAGCT GCAATGCTGC TTTCAATGAC CTCTGGAGAC TTGACCTAAA CAGCAAAGAG 
TGGATCCGAC CTTTGGCTTC AGGGTCCTAT CCTTCCCCCA AAGCTGGAGC AACTCTGGTC 
GTGTACAAGG ACTTGCTAGT GCTGTTTGGT GGCTGGACGC GGCCAAGCCC TTATCCCCTA 
CACCAGCCAG AGAGATTCTT TGATGAAATA CACACTTACT CACCCTCTAA AAATTGGTGG 
AACTGCATTG TGACAACCCA TGGGCCACCT CCCATGGCTG GCCACTCCTC CTGTGTGATA 
GATGATAAAA TGATTGTCTT TGGTGGCTCT TTAGGATCCC GGCAAATGAG CAATGATGTC 
TGGGTCCTTG ACCTTGAGCA GTGGGCGTGG TCCAAGCCGA ACATCTCTGG CCCCAGTCCT 
CATCCTCGAG GTGGCCAATC TCAGATTGTC ATAGATGATG CAACTATCTT AATCCTCGGA 
GGGTGTGGCG GTCCCAATGC TCTATTCAAG GATGCTTGGT TGTTGCACAT GCATTCTGGT 
CCTTGGGCCT GGCAGCCACT CAAGGTAGAA AATGAAGAGC ATGGGGCCCC AGAACTGTGG 
TGCCATCCAG CTTGCCGGGT GGGACAGTGT GTGGTGGTCT TCAGCCAGGC TCCTAGTGGG 
AGAGCCCCAC TCAGCCCCAG TTTGAACTCT CGCCCATCAC CTATCAGTGC CACTCCTCCA 
GCTCTCGTTC CTGAAACCCG AGAGTACCGC TCTCAGTCTC CAGTAAGAAG CATGGATGAA 
GCTCCTTGTG TTAACGGCCG CTGGGGAACA CTGAGACCCA GGGCTCAAAG GCAGACTCCT 
TCAGGTTCCC GGGAAGGGAG CCTTTCCCCA GCCAGAGGAG ACGGCTCTCC TATCCTCAAT 
GGTGGGAGTT TGTCTCCAGG AACGGCAGCT GTGGGTGGCT CTTCTTTGGA CAGTCCTGTA 
CAGGCCATAT CTCCAAGTAC TCCATCTGCT CCTGAAGGAT ACGACCTGAA AATAGGACTT 
TCTTTGGCCC CCCGACGAGG ATCACTACCA GATCAGAAAG ATCTGAGATT AGGATCCATA 
GATCTGAATT GGGATCTGAA ACCCGCTTCC AGTAGTAATC CCATGGATGG CATGGACAAT 
AGGACAGTTG GGGGAAGTAT GAGACACCCT CCTGAACAGA CAAATGGTGT GCATACCCCA 
CCTCACGTGG CCAGTGCCCT TGCAGGGGCC GTCTCCCCAG GTGCCCTGCG TCGGAGTCTG 
GAAGCCATCA AAGCGATGTC CTCCAAAGGC CCCTCGGCCT CTGCAGCACT AAGTCCTCCT 
CTTGGGTCTT CTCCAGGCTC TCCTGGGAGC CAGAGTTTGA GCAGTGGAGA AACAGTGCCC 
ATCCCTCGCC CAGGGCCTGC CCAAGGAGAT GGACATTCCT TACCTCCCAT TGCTCGCCGC 
CTGGGCCACC ACCCTCCACA GTCCCTAAAT GTTGGCAAAC CCCTATACCA GAGTATGAAC 
TGCAAGCCCA TGCAGATGTA CGTGCTGGAC ATTAAAGACA CCAAGGAGAA GGGGCGGGTC 
AAATGGAAAG TATTTAATAG CAGTTCTGTG GTTGGACCTC CTGAAACCAG CCTGCATACC 
GTGGTACAAG GCAGGGGTGA ACTCATCATA TTTGGAGGAC TCATGGACAA GAAACAGAAT 
GTGAAGTACT ATCCAAAAAC AAACGCCTTG TACTTTGTAC GAGCAAAGAG ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_061867.1
CDS	255..2408
Translation	MASSSDSEDDSFMAVDQEETVLEGTMDQDEEPHPVLEAEETRHNRSMSELPEEVLEYILSFLSPYQEHKTAALVCKQWYRLIKGVAHQCYHGFMKAVQEGNIQWESRTYPYPGTPITQRFSHSACYYDANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASGSYPSPKAGATLVVYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTHGPPPMAGHSSCVIDDKMIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPRGGQSQIVIDDATILILGGCGGPNALFKDAWLLHMHSGPWAWQPLKVENEEHGAPELWCHPACRVGQCVVVFSQAPSGRAPLSPSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQRQTPSGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRHPPEQTNGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGSSPGSPGSQSLSSGETVPIPRPGPAQGDGHSLPPIARRLGHHPPQSLNVGKPLYQSMNCKPMQMYVLDIKDTKEKGRVKWKVFNSSSVVGPPETSLHTVVQGRGELIIFGGLMDKKQNVKYYPKTNALYFVRAKR

Target ORF information:

RefSeq Version	NM_018994.2
Organism	Homo sapiens(human)
Definition	Homo sapiens F-box protein 42 (FBXO42), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018994.2

ORF Insert Sequence:

ATGGCCAGCT CCTCGGACAG TGAAGATGAC AGTTTCATGG CTGTGGACCA GGAAGAAACT 
GTGCTGGAAG GGACAATGGA TCAAGATGAG GAGCCCCACC CAGTATTGGA GGCTGAGGAG 
ACTAGACATA ATAGGTCCAT GTCGGAGCTG CCAGAAGAGG TTTTGGAGTA TATCCTGTCC 
TTTCTCTCAC CGTATCAGGA ACACAAAACT GCGGCCCTTG TCTGCAAACA GTGGTATCGA 
CTTATCAAAG GTGTAGCCCA TCAGTGTTAT CATGGTTTCA TGAAGGCTGT CCAGGAAGGA 
AACATTCAGT GGGAGAGCCG TACCTATCCT TATCCTGGAA CCCCAATCAC TCAGCGCTTC 
TCGCACAGTG CATGCTATTA TGATGCTAAT CAGTCTATGT ATGTGTTTGG AGGCTGTACC 
CAGAGCAGCT GCAATGCTGC TTTCAATGAC CTCTGGAGAC TTGACCTAAA CAGCAAAGAG 
TGGATCCGAC CTTTGGCTTC AGGGTCCTAT CCTTCCCCCA AAGCTGGAGC AACTCTGGTC 
GTGTACAAGG ACTTGCTAGT GCTGTTTGGT GGCTGGACGC GGCCAAGCCC TTATCCCCTA 
CACCAGCCAG AGAGATTCTT TGATGAAATA CACACTTACT CACCCTCTAA AAATTGGTGG 
AACTGCATTG TGACAACCCA TGGGCCACCT CCCATGGCTG GCCACTCCTC CTGTGTGATA 
GATGATAAAA TGATTGTCTT TGGTGGCTCT TTAGGATCCC GGCAAATGAG CAATGATGTC 
TGGGTCCTTG ACCTTGAGCA GTGGGCGTGG TCCAAGCCGA ACATCTCTGG CCCCAGTCCT 
CATCCTCGAG GTGGCCAATC TCAGATTGTC ATAGATGATG CAACTATCTT AATCCTCGGA 
GGGTGTGGCG GTCCCAATGC TCTATTCAAG GATGCTTGGT TGTTGCACAT GCATTCTGGT 
CCTTGGGCCT GGCAGCCACT CAAGGTAGAA AATGAAGAGC ATGGGGCCCC AGAACTGTGG 
TGCCATCCAG CTTGCCGGGT GGGACAGTGT GTGGTGGTCT TCAGCCAGGC TCCTAGTGGG 
AGAGCCCCAC TCAGCCCCAG TTTGAACTCT CGCCCATCAC CTATCAGTGC CACTCCTCCA 
GCTCTCGTTC CTGAAACCCG AGAGTACCGC TCTCAGTCTC CAGTAAGAAG CATGGATGAA 
GCTCCTTGTG TTAACGGCCG CTGGGGAACA CTGAGACCCA GGGCTCAAAG GCAGACTCCT 
TCAGGTTCCC GGGAAGGGAG CCTTTCCCCA GCCAGAGGAG ACGGCTCTCC TATCCTCAAT 
GGTGGGAGTT TGTCTCCAGG AACGGCAGCT GTGGGTGGCT CTTCTTTGGA CAGTCCTGTA 
CAGGCCATAT CTCCAAGTAC TCCATCTGCT CCTGAAGGAT ACGACCTGAA AATAGGACTT 
TCTTTGGCCC CCCGACGAGG ATCACTACCA GATCAGAAAG ATCTGAGATT AGGATCCATA 
GATCTGAATT GGGATCTGAA ACCCGCTTCC AGTAGTAATC CCATGGATGG CATGGACAAT 
AGGACAGTTG GGGGAAGTAT GAGACACCCT CCTGAACAGA CAAATGGTGT GCATACCCCA 
CCTCACGTGG CCAGTGCCCT TGCAGGGGCC GTCTCCCCAG GTGCCCTGCG TCGGAGTCTG 
GAAGCCATCA AAGCGATGTC CTCCAAAGGC CCCTCGGCCT CTGCAGCACT AAGTCCTCCT 
CTTGGGTCTT CTCCAGGCTC TCCTGGGAGC CAGAGTTTGA GCAGTGGAGA AACAGTGCCC 
ATCCCTCGCC CAGGGCCTGC CCAAGGAGAT GGACATTCCT TACCTCCCAT TGCTCGCCGC 
CTGGGCCACC ACCCTCCACA GTCCCTAAAT GTTGGCAAAC CCCTATACCA GAGTATGAAC 
TGCAAGCCCA TGCAGATGTA CGTGCTGGAC ATTAAAGACA CCAAGGAGAA GGGGCGGGTC 
AAATGGAAAG TATTTAATAG CAGTTCTGTG GTTGGACCTC CTGAAACCAG CCTGCATACC 
GTGGTACAAG GCAGGGGTGA ACTCATCATA TTTGGAGGAC TCATGGACAA GAAACAGAAT 
GTGAAGTACT ATCCAAAAAC AAACGCCTTG TACTTTGTAC GAGCAAAGAG ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

FBXO42 ( XM_006710698.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_006710761.1 Homo sapiens F-box protein 42 (FBXO42), transcript variant X1, mRNA.

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CloneID	OHu33515
Clone ID Related Accession (Same CDS sequence)	NM_018994.3 , NM_018994.2 , XM_006710698.3
Accession Version	XM_006710698.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2154bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	F-box only protein 42 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_006710698.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCAGCT CCTCGGACAG TGAAGATGAC AGTTTCATGG CTGTGGACCA GGAAGAAACT 
GTGCTGGAAG GGACAATGGA TCAAGATGAG GAGCCCCACC CAGTATTGGA GGCTGAGGAG 
ACTAGACATA ATAGGTCCAT GTCGGAGCTG CCAGAAGAGG TTTTGGAGTA TATCCTGTCC 
TTTCTCTCAC CGTATCAGGA ACACAAAACT GCGGCCCTTG TCTGCAAACA GTGGTATCGA 
CTTATCAAAG GTGTAGCCCA TCAGTGTTAT CATGGTTTCA TGAAGGCTGT CCAGGAAGGA 
AACATTCAGT GGGAGAGCCG TACCTATCCT TATCCTGGAA CCCCAATCAC TCAGCGCTTC 
TCGCACAGTG CATGCTATTA TGATGCTAAT CAGTCTATGT ATGTGTTTGG AGGCTGTACC 
CAGAGCAGCT GCAATGCTGC TTTCAATGAC CTCTGGAGAC TTGACCTAAA CAGCAAAGAG 
TGGATCCGAC CTTTGGCTTC AGGGTCCTAT CCTTCCCCCA AAGCTGGAGC AACTCTGGTC 
GTGTACAAGG ACTTGCTAGT GCTGTTTGGT GGCTGGACGC GGCCAAGCCC TTATCCCCTA 
CACCAGCCAG AGAGATTCTT TGATGAAATA CACACTTACT CACCCTCTAA AAATTGGTGG 
AACTGCATTG TGACAACCCA TGGGCCACCT CCCATGGCTG GCCACTCCTC CTGTGTGATA 
GATGATAAAA TGATTGTCTT TGGTGGCTCT TTAGGATCCC GGCAAATGAG CAATGATGTC 
TGGGTCCTTG ACCTTGAGCA GTGGGCGTGG TCCAAGCCGA ACATCTCTGG CCCCAGTCCT 
CATCCTCGAG GTGGCCAATC TCAGATTGTC ATAGATGATG CAACTATCTT AATCCTCGGA 
GGGTGTGGCG GTCCCAATGC TCTATTCAAG GATGCTTGGT TGTTGCACAT GCATTCTGGT 
CCTTGGGCCT GGCAGCCACT CAAGGTAGAA AATGAAGAGC ATGGGGCCCC AGAACTGTGG 
TGCCATCCAG CTTGCCGGGT GGGACAGTGT GTGGTGGTCT TCAGCCAGGC TCCTAGTGGG 
AGAGCCCCAC TCAGCCCCAG TTTGAACTCT CGCCCATCAC CTATCAGTGC CACTCCTCCA 
GCTCTCGTTC CTGAAACCCG AGAGTACCGC TCTCAGTCTC CAGTAAGAAG CATGGATGAA 
GCTCCTTGTG TTAACGGCCG CTGGGGAACA CTGAGACCCA GGGCTCAAAG GCAGACTCCT 
TCAGGTTCCC GGGAAGGGAG CCTTTCCCCA GCCAGAGGAG ACGGCTCTCC TATCCTCAAT 
GGTGGGAGTT TGTCTCCAGG AACGGCAGCT GTGGGTGGCT CTTCTTTGGA CAGTCCTGTA 
CAGGCCATAT CTCCAAGTAC TCCATCTGCT CCTGAAGGAT ACGACCTGAA AATAGGACTT 
TCTTTGGCCC CCCGACGAGG ATCACTACCA GATCAGAAAG ATCTGAGATT AGGATCCATA 
GATCTGAATT GGGATCTGAA ACCCGCTTCC AGTAGTAATC CCATGGATGG CATGGACAAT 
AGGACAGTTG GGGGAAGTAT GAGACACCCT CCTGAACAGA CAAATGGTGT GCATACCCCA 
CCTCACGTGG CCAGTGCCCT TGCAGGGGCC GTCTCCCCAG GTGCCCTGCG TCGGAGTCTG 
GAAGCCATCA AAGCGATGTC CTCCAAAGGC CCCTCGGCCT CTGCAGCACT AAGTCCTCCT 
CTTGGGTCTT CTCCAGGCTC TCCTGGGAGC CAGAGTTTGA GCAGTGGAGA AACAGTGCCC 
ATCCCTCGCC CAGGGCCTGC CCAAGGAGAT GGACATTCCT TACCTCCCAT TGCTCGCCGC 
CTGGGCCACC ACCCTCCACA GTCCCTAAAT GTTGGCAAAC CCCTATACCA GAGTATGAAC 
TGCAAGCCCA TGCAGATGTA CGTGCTGGAC ATTAAAGACA CCAAGGAGAA GGGGCGGGTC 
AAATGGAAAG TATTTAATAG CAGTTCTGTG GTTGGACCTC CTGAAACCAG CCTGCATACC 
GTGGTACAAG GCAGGGGTGA ACTCATCATA TTTGGAGGAC TCATGGACAA GAAACAGAAT 
GTGAAGTACT ATCCAAAAAC AAACGCCTTG TACTTTGTAC GAGCAAAGAG ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006710761.1
CDS	28..2181
Translation	MASSSDSEDDSFMAVDQEETVLEGTMDQDEEPHPVLEAEETRHNRSMSELPEEVLEYILSFLSPYQEHKTAALVCKQWYRLIKGVAHQCYHGFMKAVQEGNIQWESRTYPYPGTPITQRFSHSACYYDANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASGSYPSPKAGATLVVYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTHGPPPMAGHSSCVIDDKMIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPRGGQSQIVIDDATILILGGCGGPNALFKDAWLLHMHSGPWAWQPLKVENEEHGAPELWCHPACRVGQCVVVFSQAPSGRAPLSPSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQRQTPSGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRHPPEQTNGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGSSPGSPGSQSLSSGETVPIPRPGPAQGDGHSLPPIARRLGHHPPQSLNVGKPLYQSMNCKPMQMYVLDIKDTKEKGRVKWKVFNSSSVVGPPETSLHTVVQGRGELIIFGGLMDKKQNVKYYPKTNALYFVRAKR

Target ORF information:

RefSeq Version	XM_006710698.3
Organism	Homo sapiens(human)
Definition	Homo sapiens F-box protein 42 (FBXO42), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006710698.3

ORF Insert Sequence:

ATGGCCAGCT CCTCGGACAG TGAAGATGAC AGTTTCATGG CTGTGGACCA GGAAGAAACT 
GTGCTGGAAG GGACAATGGA TCAAGATGAG GAGCCCCACC CAGTATTGGA GGCTGAGGAG 
ACTAGACATA ATAGGTCCAT GTCGGAGCTG CCAGAAGAGG TTTTGGAGTA TATCCTGTCC 
TTTCTCTCAC CGTATCAGGA ACACAAAACT GCGGCCCTTG TCTGCAAACA GTGGTATCGA 
CTTATCAAAG GTGTAGCCCA TCAGTGTTAT CATGGTTTCA TGAAGGCTGT CCAGGAAGGA 
AACATTCAGT GGGAGAGCCG TACCTATCCT TATCCTGGAA CCCCAATCAC TCAGCGCTTC 
TCGCACAGTG CATGCTATTA TGATGCTAAT CAGTCTATGT ATGTGTTTGG AGGCTGTACC 
CAGAGCAGCT GCAATGCTGC TTTCAATGAC CTCTGGAGAC TTGACCTAAA CAGCAAAGAG 
TGGATCCGAC CTTTGGCTTC AGGGTCCTAT CCTTCCCCCA AAGCTGGAGC AACTCTGGTC 
GTGTACAAGG ACTTGCTAGT GCTGTTTGGT GGCTGGACGC GGCCAAGCCC TTATCCCCTA 
CACCAGCCAG AGAGATTCTT TGATGAAATA CACACTTACT CACCCTCTAA AAATTGGTGG 
AACTGCATTG TGACAACCCA TGGGCCACCT CCCATGGCTG GCCACTCCTC CTGTGTGATA 
GATGATAAAA TGATTGTCTT TGGTGGCTCT TTAGGATCCC GGCAAATGAG CAATGATGTC 
TGGGTCCTTG ACCTTGAGCA GTGGGCGTGG TCCAAGCCGA ACATCTCTGG CCCCAGTCCT 
CATCCTCGAG GTGGCCAATC TCAGATTGTC ATAGATGATG CAACTATCTT AATCCTCGGA 
GGGTGTGGCG GTCCCAATGC TCTATTCAAG GATGCTTGGT TGTTGCACAT GCATTCTGGT 
CCTTGGGCCT GGCAGCCACT CAAGGTAGAA AATGAAGAGC ATGGGGCCCC AGAACTGTGG 
TGCCATCCAG CTTGCCGGGT GGGACAGTGT GTGGTGGTCT TCAGCCAGGC TCCTAGTGGG 
AGAGCCCCAC TCAGCCCCAG TTTGAACTCT CGCCCATCAC CTATCAGTGC CACTCCTCCA 
GCTCTCGTTC CTGAAACCCG AGAGTACCGC TCTCAGTCTC CAGTAAGAAG CATGGATGAA 
GCTCCTTGTG TTAACGGCCG CTGGGGAACA CTGAGACCCA GGGCTCAAAG GCAGACTCCT 
TCAGGTTCCC GGGAAGGGAG CCTTTCCCCA GCCAGAGGAG ACGGCTCTCC TATCCTCAAT 
GGTGGGAGTT TGTCTCCAGG AACGGCAGCT GTGGGTGGCT CTTCTTTGGA CAGTCCTGTA 
CAGGCCATAT CTCCAAGTAC TCCATCTGCT CCTGAAGGAT ACGACCTGAA AATAGGACTT 
TCTTTGGCCC CCCGACGAGG ATCACTACCA GATCAGAAAG ATCTGAGATT AGGATCCATA 
GATCTGAATT GGGATCTGAA ACCCGCTTCC AGTAGTAATC CCATGGATGG CATGGACAAT 
AGGACAGTTG GGGGAAGTAT GAGACACCCT CCTGAACAGA CAAATGGTGT GCATACCCCA 
CCTCACGTGG CCAGTGCCCT TGCAGGGGCC GTCTCCCCAG GTGCCCTGCG TCGGAGTCTG 
GAAGCCATCA AAGCGATGTC CTCCAAAGGC CCCTCGGCCT CTGCAGCACT AAGTCCTCCT 
CTTGGGTCTT CTCCAGGCTC TCCTGGGAGC CAGAGTTTGA GCAGTGGAGA AACAGTGCCC 
ATCCCTCGCC CAGGGCCTGC CCAAGGAGAT GGACATTCCT TACCTCCCAT TGCTCGCCGC 
CTGGGCCACC ACCCTCCACA GTCCCTAAAT GTTGGCAAAC CCCTATACCA GAGTATGAAC 
TGCAAGCCCA TGCAGATGTA CGTGCTGGAC ATTAAAGACA CCAAGGAGAA GGGGCGGGTC 
AAATGGAAAG TATTTAATAG CAGTTCTGTG GTTGGACCTC CTGAAACCAG CCTGCATACC 
GTGGTACAAG GCAGGGGTGA ACTCATCATA TTTGGAGGAC TCATGGACAA GAAACAGAAT 
GTGAAGTACT ATCCAAAAAC AAACGCCTTG TACTTTGTAC GAGCAAAGAG ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

SCF(JFK) is a bona fide E3 ligase for ING4 and a potent promoter of the angiogenesis and metastasis of breast cancer.
Genes & development29(6)672-85(2015 Mar)
Yan R,He L,Li Z,Han X,Liang J,Si W,Chen Z,Li L,Xie G,Li W,Wang P,Lei L,Zhang H,Pei F,Cao D,Sun L,Shang Y

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.
Molecular systems biology11(1)775(2015 Jan)
Li X,Wang W,Wang J,Malovannaya A,Xi Y,Li W,Guerra R,Hawke DH,Qin J,Chen J

Genetic analysis of the FBXO42 gene in Chinese Han patients with Parkinson's disease.
BMC neurology13125(2013 Sep)
Gao K,Deng X,Zheng W,Song Z,Zhu A,Xiu X,Deng H

Substrate phosphorylation and feedback regulation in JFK-promoted p53 destabilization.
The Journal of biological chemistry286(6)4226-35(2011 Feb)
Sun L,Shi L,Wang F,Huangyang P,Si W,Yang J,Yao Z,Shang Y

JFK, a Kelch domain-containing F-box protein, links the SCF complex to p53 regulation.
Proceedings of the National Academy of Sciences of the United States of America106(25)10195-200(2009 Jun)
Sun L,Shi L,Li W,Yu W,Liang J,Zhang H,Yang X,Wang Y,Li R,Yao X,Yi X,Shang Y

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FBXO42 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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