TAS2R5 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TAS2R5
Entrez Gene ID	54429
Full Name	taste 2 receptor member 5
Synonyms	T2R5
General protein information	Preferred Names taste 2 receptor member 5 Names taste receptor type 2 member 5 taste receptor, type 2, member 5
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 7 Map Location: 7q34
Summary	This gene encodes a bitter taste receptor; bitter taste receptors are members of the G protein-coupled receptor superfamily and are specifically expressed by taste receptor cells of the tongue and palate epithelia. Each of these apparently intronless taste receptor genes encodes a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is clustered with another 3 candidate taste receptor genes on chromosome 7 and is genetically linked to loci that influence bitter perception. [provided by RefSeq, Jul 2008].
Disorder MIM:	605062

mRNA and Protein(s)

mRNA	Protein	Name
NM_018980.3	NP_061853.1	taste receptor type 2 member 5
NM_018980.2	NP_061853.1	taste receptor type 2 member 5

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	TAS2R5	NP_001009104.1
	TAS2R5	NP_001074227.1
Canis lupus familiaris (dog)	TAS2R5	NP_001138978.1
Homo sapiens (human)	TAS2R5	NP_061853.1

Gene Ontology
Bibliography

Related articles in PubMed

Genetic variants associated with disordered eating.
Wade TD, Gordon S, Medland S, Bulik CM, Heath AC, Montgomery GW, Martin NG
The International journal of eating disorders46(6)594-608(2013 Sep)

The molecular receptive ranges of human TAS2R bitter taste receptors.
Meyerhof W, Batram C, Kuhn C, Brockhoff A, Chudoba E, Bufe B, Appendino G, Behrens M
Chemical senses35(2)157-70(2010 Feb)

The receptors and cells for mammalian taste.
Chandrashekar J, Hoon MA, Ryba NJ, Zuker CS
Nature444(7117)288-94(2006 Nov)

Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates.
Go Y, Satta Y, Takenaka O, Takahata N
Genetics170(1)313-26(2005 May)

Evolution of bitter taste receptors in humans and apes.
Fischer A, Gilad Y, Man O, P??bo S
Molecular biology and evolution22(3)432-6(2005 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following TAS2R5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TAS2R5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu16210	NM_018980.3 Latest version!	Homo sapiens taste 2 receptor member 5 (TAS2R5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
View Old Accession Versions >>
OHu16210	NM_018980.2	Homo sapiens taste 2 receptor member 5 (TAS2R5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TAS2R5 ( NM_018980.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_061853.1 Homo sapiens taste 2 receptor member 5 (TAS2R5), mRNA.

Price & Availability↑

CloneID	OHu16210
Clone ID Related Accession (Same CDS sequence)	NM_018980.3 , NM_018980.2
Accession Version	NM_018980.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 900bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-26
Organism	Homo sapiens(human)
Product	taste receptor type 2 member 5
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC095522.1, AW881072.1 and AC004979.1. On May 17, 2019 this sequence version replaced NM_018980.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript is intronless :: BC095522.1, SRR1660803.244645.1 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000247883.5/ ENSP00000247883.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGCTGAGCG CTGGCCTAGG ACTGCTGATG CTGGTGGCAG TGGTTGAATT TCTCATCGGT 
TTAATTGGAA ATGGAAGCCT GGTGGTCTGG AGTTTTAGAG AATGGATCAG AAAATTCAAC 
TGGTCCTCAT ATAACCTCAT TATCCTGGGC CTGGCTGGCT GCCGATTTCT CCTGCAGTGG 
CTGATCATTT TGGACTTAAG CTTGTTTCCA CTTTTCCAGA GCAGCCGTTG GCTTCGCTAT 
CTTAGTATCT TCTGGGTCCT GGTAAGCCAG GCCAGCTTAT GGTTTGCCAC CTTCCTCAGT 
GTCTTCTATT GCAAGAAGAT CACGACCTTC GATCGCCCGG CCTACTTGTG GCTGAAGCAG 
AGGGCCTATA ACCTGAGTCT CTGGTGCCTT CTGGGCTACT TTATAATCAA TTTGTTACTT 
ACAGTCCAAA TTGGCTTAAC ATTCTATCAT CCTCCCCAAG GAAACAGCAG CATTCGGTAT 
CCCTTTGAAA GCTGGCAGTA CCTGTATGCA TTTCAGCTCA ATTCAGGAAG TTATTTGCCT 
TTAGTGGTGT TTCTTGTTTC CTCTGGGATG CTGATTGTCT CTTTGTATAC ACACCACAAG 
AAGATGAAGG TCCATTCAGC TGGTAGGAGG GATGTCCGGG CCAAGGCTCA CATCACTGCG 
CTGAAGTCCT TGGGCTGCTT CCTCTTACTT CACCTGGTTT ATATCATGGC CAGCCCCTTC 
TCCATCACCT CCAAGACTTA TCCTCCTGAT CTCACCAGTG TCTTCATCTG GGAGACACTC 
ATGGCAGCCT ATCCTTCTCT TCATTCTCTC ATATTGATCA TGGGGATTCC TAGGGTGAAG 
CAGACTTGTC AGAAGATCCT GTGGAAGACA GTGTGTGCTC GGAGATGCTG GGGCCCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_061853.1
CDS	146..1045
Translation	MLSAGLGLLMLVAVVEFLIGLIGNGSLVVWSFREWIRKFNWSSYNLIILGLAGCRFLLQWLIILDLSLFPLFQSSRWLRYLSIFWVLVSQASLWFATFLSVFYCKKITTFDRPAYLWLKQRAYNLSLWCLLGYFIINLLLTVQIGLTFYHPPQGNSSIRYPFESWQYLYAFQLNSGSYLPLVVFLVSSGMLIVSLYTHHKKMKVHSAGRRDVRAKAHITALKSLGCFLLLHLVYIMASPFSITSKTYPPDLTSVFIWETLMAAYPSLHSLILIMGIPRVKQTCQKILWKTVCARRCWGP

Target ORF information:

RefSeq Version	NM_018980.3
Organism	Homo sapiens(human)
Definition	Homo sapiens taste 2 receptor member 5 (TAS2R5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018980.3

ORF Insert Sequence:

ATGCTGAGCG CTGGCCTAGG ACTGCTGATG CTGGTGGCAG TGGTTGAATT TCTCATCGGT 
TTAATTGGAA ATGGAAGCCT GGTGGTCTGG AGTTTTAGAG AATGGATCAG AAAATTCAAC 
TGGTCCTCAT ATAACCTCAT TATCCTGGGC CTGGCTGGCT GCCGATTTCT CCTGCAGTGG 
CTGATCATTT TGGACTTAAG CTTGTTTCCA CTTTTCCAGA GCAGCCGTTG GCTTCGCTAT 
CTTAGTATCT TCTGGGTCCT GGTAAGCCAG GCCAGCTTAT GGTTTGCCAC CTTCCTCAGT 
GTCTTCTATT GCAAGAAGAT CACGACCTTC GATCGCCCGG CCTACTTGTG GCTGAAGCAG 
AGGGCCTATA ACCTGAGTCT CTGGTGCCTT CTGGGCTACT TTATAATCAA TTTGTTACTT 
ACAGTCCAAA TTGGCTTAAC ATTCTATCAT CCTCCCCAAG GAAACAGCAG CATTCGGTAT 
CCCTTTGAAA GCTGGCAGTA CCTGTATGCA TTTCAGCTCA ATTCAGGAAG TTATTTGCCT 
TTAGTGGTGT TTCTTGTTTC CTCTGGGATG CTGATTGTCT CTTTGTATAC ACACCACAAG 
AAGATGAAGG TCCATTCAGC TGGTAGGAGG GATGTCCGGG CCAAGGCTCA CATCACTGCG 
CTGAAGTCCT TGGGCTGCTT CCTCTTACTT CACCTGGTTT ATATCATGGC CAGCCCCTTC 
TCCATCACCT CCAAGACTTA TCCTCCTGAT CTCACCAGTG TCTTCATCTG GGAGACACTC 
ATGGCAGCCT ATCCTTCTCT TCATTCTCTC ATATTGATCA TGGGGATTCC TAGGGTGAAG 
CAGACTTGTC AGAAGATCCT GTGGAAGACA GTGTGTGCTC GGAGATGCTG GGGCCCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TAS2R5 ( NM_018980.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_061853.1 Homo sapiens taste 2 receptor member 5 (TAS2R5), mRNA.

Price & Availability↑

CloneID	OHu16210
Clone ID Related Accession (Same CDS sequence)	NM_018980.3 , NM_018980.2
Accession Version	NM_018980.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 900bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Homo sapiens(human)
Product	taste receptor type 2 member 5
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC095522.1 and AW881072.1. On Jun 17, 2005 this sequence version replaced NM_018980.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.

ATGCTGAGCG CTGGCCTAGG ACTGCTGATG CTGGTGGCAG TGGTTGAATT TCTCATCGGT 
TTAATTGGAA ATGGAAGCCT GGTGGTCTGG AGTTTTAGAG AATGGATCAG AAAATTCAAC 
TGGTCCTCAT ATAACCTCAT TATCCTGGGC CTGGCTGGCT GCCGATTTCT CCTGCAGTGG 
CTGATCATTT TGGACTTAAG CTTGTTTCCA CTTTTCCAGA GCAGCCGTTG GCTTCGCTAT 
CTTAGTATCT TCTGGGTCCT GGTAAGCCAG GCCAGCTTAT GGTTTGCCAC CTTCCTCAGT 
GTCTTCTATT GCAAGAAGAT CACGACCTTC GATCGCCCGG CCTACTTGTG GCTGAAGCAG 
AGGGCCTATA ACCTGAGTCT CTGGTGCCTT CTGGGCTACT TTATAATCAA TTTGTTACTT 
ACAGTCCAAA TTGGCTTAAC ATTCTATCAT CCTCCCCAAG GAAACAGCAG CATTCGGTAT 
CCCTTTGAAA GCTGGCAGTA CCTGTATGCA TTTCAGCTCA ATTCAGGAAG TTATTTGCCT 
TTAGTGGTGT TTCTTGTTTC CTCTGGGATG CTGATTGTCT CTTTGTATAC ACACCACAAG 
AAGATGAAGG TCCATTCAGC TGGTAGGAGG GATGTCCGGG CCAAGGCTCA CATCACTGCG 
CTGAAGTCCT TGGGCTGCTT CCTCTTACTT CACCTGGTTT ATATCATGGC CAGCCCCTTC 
TCCATCACCT CCAAGACTTA TCCTCCTGAT CTCACCAGTG TCTTCATCTG GGAGACACTC 
ATGGCAGCCT ATCCTTCTCT TCATTCTCTC ATATTGATCA TGGGGATTCC TAGGGTGAAG 
CAGACTTGTC AGAAGATCCT GTGGAAGACA GTGTGTGCTC GGAGATGCTG GGGCCCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_061853.1
CDS	146..1045
Translation	MLSAGLGLLMLVAVVEFLIGLIGNGSLVVWSFREWIRKFNWSSYNLIILGLAGCRFLLQWLIILDLSLFPLFQSSRWLRYLSIFWVLVSQASLWFATFLSVFYCKKITTFDRPAYLWLKQRAYNLSLWCLLGYFIINLLLTVQIGLTFYHPPQGNSSIRYPFESWQYLYAFQLNSGSYLPLVVFLVSSGMLIVSLYTHHKKMKVHSAGRRDVRAKAHITALKSLGCFLLLHLVYIMASPFSITSKTYPPDLTSVFIWETLMAAYPSLHSLILIMGIPRVKQTCQKILWKTVCARRCWGP

Target ORF information:

RefSeq Version	NM_018980.2
Organism	Homo sapiens(human)
Definition	Homo sapiens taste 2 receptor member 5 (TAS2R5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018980.2

ORF Insert Sequence:

ATGCTGAGCG CTGGCCTAGG ACTGCTGATG CTGGTGGCAG TGGTTGAATT TCTCATCGGT 
TTAATTGGAA ATGGAAGCCT GGTGGTCTGG AGTTTTAGAG AATGGATCAG AAAATTCAAC 
TGGTCCTCAT ATAACCTCAT TATCCTGGGC CTGGCTGGCT GCCGATTTCT CCTGCAGTGG 
CTGATCATTT TGGACTTAAG CTTGTTTCCA CTTTTCCAGA GCAGCCGTTG GCTTCGCTAT 
CTTAGTATCT TCTGGGTCCT GGTAAGCCAG GCCAGCTTAT GGTTTGCCAC CTTCCTCAGT 
GTCTTCTATT GCAAGAAGAT CACGACCTTC GATCGCCCGG CCTACTTGTG GCTGAAGCAG 
AGGGCCTATA ACCTGAGTCT CTGGTGCCTT CTGGGCTACT TTATAATCAA TTTGTTACTT 
ACAGTCCAAA TTGGCTTAAC ATTCTATCAT CCTCCCCAAG GAAACAGCAG CATTCGGTAT 
CCCTTTGAAA GCTGGCAGTA CCTGTATGCA TTTCAGCTCA ATTCAGGAAG TTATTTGCCT 
TTAGTGGTGT TTCTTGTTTC CTCTGGGATG CTGATTGTCT CTTTGTATAC ACACCACAAG 
AAGATGAAGG TCCATTCAGC TGGTAGGAGG GATGTCCGGG CCAAGGCTCA CATCACTGCG 
CTGAAGTCCT TGGGCTGCTT CCTCTTACTT CACCTGGTTT ATATCATGGC CAGCCCCTTC 
TCCATCACCT CCAAGACTTA TCCTCCTGAT CTCACCAGTG TCTTCATCTG GGAGACACTC 
ATGGCAGCCT ATCCTTCTCT TCATTCTCTC ATATTGATCA TGGGGATTCC TAGGGTGAAG 
CAGACTTGTC AGAAGATCCT GTGGAAGACA GTGTGTGCTC GGAGATGCTG GGGCCCATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Genetic variants associated with disordered eating.
The International journal of eating disorders46(6)594-608(2013 Sep)
Wade TD,Gordon S,Medland S,Bulik CM,Heath AC,Montgomery GW,Martin NG

The molecular receptive ranges of human TAS2R bitter taste receptors.
Chemical senses35(2)157-70(2010 Feb)
Meyerhof W,Batram C,Kuhn C,Brockhoff A,Chudoba E,Bufe B,Appendino G,Behrens M

The receptors and cells for mammalian taste.
Nature444(7117)288-94(2006 Nov)
Chandrashekar J,Hoon MA,Ryba NJ,Zuker CS

Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates.
Genetics170(1)313-26(2005 May)
Go Y,Satta Y,Takenaka O,Takahata N

Evolution of bitter taste receptors in humans and apes.
Molecular biology and evolution22(3)432-6(2005 Mar)
Fischer A,Gilad Y,Man O,P??bo S

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TAS2R5 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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