NANS cDNA ORF clone, Homo sapiens(human)

The following NANS gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the NANS cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OHu68280 XM_024447574.1
Latest version!
Homo sapiens N-acetylneuraminate synthase (NANS), transcript variant X1, mRNA. pcDNA3.1-C-(k)DYK or customized vector 5-7 $139.30
$199.00
OHu68280 XM_011518787.2
Latest version!
Homo sapiens N-acetylneuraminate synthase (NANS), transcript variant X2, mRNA. pcDNA3.1-C-(k)DYK or customized vector 5-7 $139.30
$199.00
OHu09177 NM_018946.4
Latest version!
Homo sapiens N-acetylneuraminate synthase (NANS), mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $69.30
$99.00
OHu68281 XM_011518788.2
Latest version!
Homo sapiens N-acetylneuraminate synthase (NANS), transcript variant X3, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $139.30
$199.00
OHu98695 XM_017014811.1
Latest version!
Homo sapiens N-acetylneuraminate synthase (NANS), transcript variant X4, mRNA. pcDNA3.1-C-(k)DYK or customized vector 9-11 $139.30
$199.00
View Old Accession Versions >>
OHu09177 NM_018946.3 Homo sapiens N-acetylneuraminate synthase (NANS), mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $69.30
$99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

  • Reference Sequences (Refseq)
    CloneID OHu68280
    Clone ID Related Accession (Same CDS sequence) XM_011518787.2 , XM_024447574.1
    Accession Version XM_011518787.2 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 732bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-05
    Organism Homo sapiens(human)
    Product sialic acid synthase isoform X1
    Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000009.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011518787.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    ATGGCAGTTG AATTCCTGCA TGAACTGAAT GTTCCATTTT TCAAAGTTGG ATCTGGAGAC 
    ACTAATAATT TTCCTTATCT GGAAAAGACA GCCAAAAAAG GTCGCCCAAT GGTGATCTCC
    AGTGGGATGC AGTCAATGGA CACCATGAAG CAAGTTTATC AGATCGTGAA GCCCCTCAAC
    CCCAACTTCT GCTTCTTGCA GTGTACCAGC GCATACCCGC TCCAGCCTGA GGACGTCAAC
    CTGCGGGTCA TCTCGGAATA TCAGAAGCTC TTTCCTGACA TTCCCATAGG GTATTCTGGG
    CATGAAACAG GCATAGCGAT ATCTGTGGCC GCAGTGGCTC TGGGGGCCAA GGTGTTGGAA
    CGTCACATAA CTTTGGACAA GACCTGGAAG GGGAGTGACC ACTCGGCCTC GCTGGAGCCT
    GGAGAACTGG CCGAGCTGGT GCGGTCAGTG CGTCTTGTGG AGCGTGCCCT GGGCTCCCCA
    ACCAAGCAGC TGCTGCCCTG TGAGATGGCC TGCAATGAGA AGCTGGGCAA GTCTGTGGTG
    GCCAAAGTGA AAATTCCGGA AGGCACCATT CTAACAATGG ACATGCTCAC CGTGAAGGTG
    GGTGAGCCCA AAGGCTATCC TCCTGAAGAC ATCTTTAATC TAGTGGGCAA GAAGGTCCTG
    GTCACTGTTG AAGAGGATGA CACCATCATG GAAGAATTGG TAGATAATCA TGGCAAAAAA
    ATCAAGTCTT AA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq XP_011517089.1
    CDS237..968
    Translation

    Target ORF information:

    RefSeq Version XM_011518787.2
    Organism Homo sapiens(human)
    Definition Homo sapiens N-acetylneuraminate synthase (NANS), transcript variant X2, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    XM_011518787.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    ATGGCAGTTG AATTCCTGCA TGAACTGAAT GTTCCATTTT TCAAAGTTGG ATCTGGAGAC 
    ACTAATAATT TTCCTTATCT GGAAAAGACA GCCAAAAAAG GTCGCCCAAT GGTGATCTCC
    AGTGGGATGC AGTCAATGGA CACCATGAAG CAAGTTTATC AGATCGTGAA GCCCCTCAAC
    CCCAACTTCT GCTTCTTGCA GTGTACCAGC GCATACCCGC TCCAGCCTGA GGACGTCAAC
    CTGCGGGTCA TCTCGGAATA TCAGAAGCTC TTTCCTGACA TTCCCATAGG GTATTCTGGG
    CATGAAACAG GCATAGCGAT ATCTGTGGCC GCAGTGGCTC TGGGGGCCAA GGTGTTGGAA
    CGTCACATAA CTTTGGACAA GACCTGGAAG GGGAGTGACC ACTCGGCCTC GCTGGAGCCT
    GGAGAACTGG CCGAGCTGGT GCGGTCAGTG CGTCTTGTGG AGCGTGCCCT GGGCTCCCCA
    ACCAAGCAGC TGCTGCCCTG TGAGATGGCC TGCAATGAGA AGCTGGGCAA GTCTGTGGTG
    GCCAAAGTGA AAATTCCGGA AGGCACCATT CTAACAATGG ACATGCTCAC CGTGAAGGTG
    GGTGAGCCCA AAGGCTATCC TCCTGAAGAC ATCTTTAATC TAGTGGGCAA GAAGGTCCTG
    GTCACTGTTG AAGAGGATGA CACCATCATG GAAGAATTGG TAGATAATCA TGGCAAAAAA
    ATCAAGTCTT AA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu68280
    Clone ID Related Accession (Same CDS sequence) XM_011518787.2 , XM_024447574.1
    Accession Version XM_024447574.1 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 732bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-05
    Organism Homo sapiens(human)
    Product sialic acid synthase isoform X1
    Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000009.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    ATGGCAGTTG AATTCCTGCA TGAACTGAAT GTTCCATTTT TCAAAGTTGG ATCTGGAGAC 
    ACTAATAATT TTCCTTATCT GGAAAAGACA GCCAAAAAAG GTCGCCCAAT GGTGATCTCC
    AGTGGGATGC AGTCAATGGA CACCATGAAG CAAGTTTATC AGATCGTGAA GCCCCTCAAC
    CCCAACTTCT GCTTCTTGCA GTGTACCAGC GCATACCCGC TCCAGCCTGA GGACGTCAAC
    CTGCGGGTCA TCTCGGAATA TCAGAAGCTC TTTCCTGACA TTCCCATAGG GTATTCTGGG
    CATGAAACAG GCATAGCGAT ATCTGTGGCC GCAGTGGCTC TGGGGGCCAA GGTGTTGGAA
    CGTCACATAA CTTTGGACAA GACCTGGAAG GGGAGTGACC ACTCGGCCTC GCTGGAGCCT
    GGAGAACTGG CCGAGCTGGT GCGGTCAGTG CGTCTTGTGG AGCGTGCCCT GGGCTCCCCA
    ACCAAGCAGC TGCTGCCCTG TGAGATGGCC TGCAATGAGA AGCTGGGCAA GTCTGTGGTG
    GCCAAAGTGA AAATTCCGGA AGGCACCATT CTAACAATGG ACATGCTCAC CGTGAAGGTG
    GGTGAGCCCA AAGGCTATCC TCCTGAAGAC ATCTTTAATC TAGTGGGCAA GAAGGTCCTG
    GTCACTGTTG AAGAGGATGA CACCATCATG GAAGAATTGG TAGATAATCA TGGCAAAAAA
    ATCAAGTCTT AA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq XP_024303342.1
    CDS1778..2509
    Translation

    Target ORF information:

    RefSeq Version XM_024447574.1
    Organism Homo sapiens(human)
    Definition Homo sapiens N-acetylneuraminate synthase (NANS), transcript variant X1, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    XM_024447574.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    ATGGCAGTTG AATTCCTGCA TGAACTGAAT GTTCCATTTT TCAAAGTTGG ATCTGGAGAC 
    ACTAATAATT TTCCTTATCT GGAAAAGACA GCCAAAAAAG GTCGCCCAAT GGTGATCTCC
    AGTGGGATGC AGTCAATGGA CACCATGAAG CAAGTTTATC AGATCGTGAA GCCCCTCAAC
    CCCAACTTCT GCTTCTTGCA GTGTACCAGC GCATACCCGC TCCAGCCTGA GGACGTCAAC
    CTGCGGGTCA TCTCGGAATA TCAGAAGCTC TTTCCTGACA TTCCCATAGG GTATTCTGGG
    CATGAAACAG GCATAGCGAT ATCTGTGGCC GCAGTGGCTC TGGGGGCCAA GGTGTTGGAA
    CGTCACATAA CTTTGGACAA GACCTGGAAG GGGAGTGACC ACTCGGCCTC GCTGGAGCCT
    GGAGAACTGG CCGAGCTGGT GCGGTCAGTG CGTCTTGTGG AGCGTGCCCT GGGCTCCCCA
    ACCAAGCAGC TGCTGCCCTG TGAGATGGCC TGCAATGAGA AGCTGGGCAA GTCTGTGGTG
    GCCAAAGTGA AAATTCCGGA AGGCACCATT CTAACAATGG ACATGCTCAC CGTGAAGGTG
    GGTGAGCCCA AAGGCTATCC TCCTGAAGAC ATCTTTAATC TAGTGGGCAA GAAGGTCCTG
    GTCACTGTTG AAGAGGATGA CACCATCATG GAAGAATTGG TAGATAATCA TGGCAAAAAA
    ATCAAGTCTT AA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu09177
    Clone ID Related Accession (Same CDS sequence) NM_018946.3 , NM_018946.4
    Accession Version NM_018946.3 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1080bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2017-09-10
    Organism Homo sapiens(human)
    Product sialic acid synthase
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL526281.3, AK316608.1 and BQ446501.1. This sequence is a reference standard in the RefSeqGene project. On Aug 8, 2008 this sequence version replaced NM_018946.2. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.365768.1, SRR1163658.50337.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
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    121
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    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGCCGCTGG AGCTGGAGCT GTGTCCCGGG CGCTGGGTGG GCGGGCAACA CCCGTGCTTC 
    ATCATTGCCG AGATCGGCCA GAACCACCAG GGCGACCTGG ACGTAGCCAA GCGCATGATC
    CGCATGGCCA AGGAGTGTGG GGCTGATTGT GCTAAGTTCC AGAAGAGTGA GCTAGAATTC
    AAGTTTAATC GGAAAGCCTT GGAGAGGCCA TACACCTCGA AGCATTCCTG GGGGAAGACG
    TACGGGGAGC ACAAACGACA TCTGGAGTTC AGCCATGACC AGTACAGGGA GCTGCAGAGG
    TACGCCGAGG AGGTTGGGAT CTTCTTCACT GCCTCTGGCA TGGATGAGAT GGCAGTTGAA
    TTCCTGCATG AACTGAATGT TCCATTTTTC AAAGTTGGAT CTGGAGACAC TAATAATTTT
    CCTTATCTGG AAAAGACAGC CAAAAAAGGT CGCCCAATGG TGATCTCCAG TGGGATGCAG
    TCAATGGACA CCATGAAGCA AGTTTATCAG ATCGTGAAGC CCCTCAACCC CAACTTCTGC
    TTCTTGCAGT GTACCAGCGC ATACCCGCTC CAGCCTGAGG ACGTCAACCT GCGGGTCATC
    TCGGAATATC AGAAGCTCTT TCCTGACATT CCCATAGGGT ATTCTGGGCA TGAAACAGGC
    ATAGCGATAT CTGTGGCCGC AGTGGCTCTG GGGGCCAAGG TGTTGGAACG TCACATAACT
    TTGGACAAGA CCTGGAAGGG GAGTGACCAC TCGGCCTCGC TGGAGCCTGG AGAACTGGCC
    GAGCTGGTGC GGTCAGTGCG TCTTGTGGAG CGTGCCCTGG GCTCCCCAAC CAAGCAGCTG
    CTGCCCTGTG AGATGGCCTG CAATGAGAAG CTGGGCAAGT CTGTGGTGGC CAAAGTGAAA
    ATTCCGGAAG GCACCATTCT AACAATGGAC ATGCTCACCG TGAAGGTGGG TGAGCCCAAA
    GGCTATCCTC CTGAAGACAT CTTTAATCTA GTGGGCAAGA AGGTCCTGGT CACTGTTGAA
    GAGGATGACA CCATCATGGA AGAATTGGTA GATAATCATG GCAAAAAAAT CAAGTCTTAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_061819.2
    CDS133..1212
    Translation

    Target ORF information:

    RefSeq Version NM_018946.3
    Organism Homo sapiens(human)
    Definition Homo sapiens N-acetylneuraminate synthase (NANS), mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_018946.3

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGCCGCTGG AGCTGGAGCT GTGTCCCGGG CGCTGGGTGG GCGGGCAACA CCCGTGCTTC 
    ATCATTGCCG AGATCGGCCA GAACCACCAG GGCGACCTGG ACGTAGCCAA GCGCATGATC
    CGCATGGCCA AGGAGTGTGG GGCTGATTGT GCTAAGTTCC AGAAGAGTGA GCTAGAATTC
    AAGTTTAATC GGAAAGCCTT GGAGAGGCCA TACACCTCGA AGCATTCCTG GGGGAAGACG
    TACGGGGAGC ACAAACGACA TCTGGAGTTC AGCCATGACC AGTACAGGGA GCTGCAGAGG
    TACGCCGAGG AGGTTGGGAT CTTCTTCACT GCCTCTGGCA TGGATGAGAT GGCAGTTGAA
    TTCCTGCATG AACTGAATGT TCCATTTTTC AAAGTTGGAT CTGGAGACAC TAATAATTTT
    CCTTATCTGG AAAAGACAGC CAAAAAAGGT CGCCCAATGG TGATCTCCAG TGGGATGCAG
    TCAATGGACA CCATGAAGCA AGTTTATCAG ATCGTGAAGC CCCTCAACCC CAACTTCTGC
    TTCTTGCAGT GTACCAGCGC ATACCCGCTC CAGCCTGAGG ACGTCAACCT GCGGGTCATC
    TCGGAATATC AGAAGCTCTT TCCTGACATT CCCATAGGGT ATTCTGGGCA TGAAACAGGC
    ATAGCGATAT CTGTGGCCGC AGTGGCTCTG GGGGCCAAGG TGTTGGAACG TCACATAACT
    TTGGACAAGA CCTGGAAGGG GAGTGACCAC TCGGCCTCGC TGGAGCCTGG AGAACTGGCC
    GAGCTGGTGC GGTCAGTGCG TCTTGTGGAG CGTGCCCTGG GCTCCCCAAC CAAGCAGCTG
    CTGCCCTGTG AGATGGCCTG CAATGAGAAG CTGGGCAAGT CTGTGGTGGC CAAAGTGAAA
    ATTCCGGAAG GCACCATTCT AACAATGGAC ATGCTCACCG TGAAGGTGGG TGAGCCCAAA
    GGCTATCCTC CTGAAGACAT CTTTAATCTA GTGGGCAAGA AGGTCCTGGT CACTGTTGAA
    GAGGATGACA CCATCATGGA AGAATTGGTA GATAATCATG GCAAAAAAAT CAAGTCTTAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu09177
    Clone ID Related Accession (Same CDS sequence) NM_018946.3 , NM_018946.4
    Accession Version NM_018946.4 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1080bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-08-21
    Organism Homo sapiens(human)
    Product sialic acid synthase
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK316608.1 and BQ446501.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_018946.3. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.231306.1, BC000008.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000210444.6/ ENSP00000210444.5 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGCCGCTGG AGCTGGAGCT GTGTCCCGGG CGCTGGGTGG GCGGGCAACA CCCGTGCTTC 
    ATCATTGCCG AGATCGGCCA GAACCACCAG GGCGACCTGG ACGTAGCCAA GCGCATGATC
    CGCATGGCCA AGGAGTGTGG GGCTGATTGT GCTAAGTTCC AGAAGAGTGA GCTAGAATTC
    AAGTTTAATC GGAAAGCCTT GGAGAGGCCA TACACCTCGA AGCATTCCTG GGGGAAGACG
    TACGGGGAGC ACAAACGACA TCTGGAGTTC AGCCATGACC AGTACAGGGA GCTGCAGAGG
    TACGCCGAGG AGGTTGGGAT CTTCTTCACT GCCTCTGGCA TGGATGAGAT GGCAGTTGAA
    TTCCTGCATG AACTGAATGT TCCATTTTTC AAAGTTGGAT CTGGAGACAC TAATAATTTT
    CCTTATCTGG AAAAGACAGC CAAAAAAGGT CGCCCAATGG TGATCTCCAG TGGGATGCAG
    TCAATGGACA CCATGAAGCA AGTTTATCAG ATCGTGAAGC CCCTCAACCC CAACTTCTGC
    TTCTTGCAGT GTACCAGCGC ATACCCGCTC CAGCCTGAGG ACGTCAACCT GCGGGTCATC
    TCGGAATATC AGAAGCTCTT TCCTGACATT CCCATAGGGT ATTCTGGGCA TGAAACAGGC
    ATAGCGATAT CTGTGGCCGC AGTGGCTCTG GGGGCCAAGG TGTTGGAACG TCACATAACT
    TTGGACAAGA CCTGGAAGGG GAGTGACCAC TCGGCCTCGC TGGAGCCTGG AGAACTGGCC
    GAGCTGGTGC GGTCAGTGCG TCTTGTGGAG CGTGCCCTGG GCTCCCCAAC CAAGCAGCTG
    CTGCCCTGTG AGATGGCCTG CAATGAGAAG CTGGGCAAGT CTGTGGTGGC CAAAGTGAAA
    ATTCCGGAAG GCACCATTCT AACAATGGAC ATGCTCACCG TGAAGGTGGG TGAGCCCAAA
    GGCTATCCTC CTGAAGACAT CTTTAATCTA GTGGGCAAGA AGGTCCTGGT CACTGTTGAA
    GAGGATGACA CCATCATGGA AGAATTGGTA GATAATCATG GCAAAAAAAT CAAGTCTTAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_061819.2
    CDS78..1157
    Translation

    Target ORF information:

    RefSeq Version NM_018946.4
    Organism Homo sapiens(human)
    Definition Homo sapiens N-acetylneuraminate synthase (NANS), mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_018946.4

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGCCGCTGG AGCTGGAGCT GTGTCCCGGG CGCTGGGTGG GCGGGCAACA CCCGTGCTTC 
    ATCATTGCCG AGATCGGCCA GAACCACCAG GGCGACCTGG ACGTAGCCAA GCGCATGATC
    CGCATGGCCA AGGAGTGTGG GGCTGATTGT GCTAAGTTCC AGAAGAGTGA GCTAGAATTC
    AAGTTTAATC GGAAAGCCTT GGAGAGGCCA TACACCTCGA AGCATTCCTG GGGGAAGACG
    TACGGGGAGC ACAAACGACA TCTGGAGTTC AGCCATGACC AGTACAGGGA GCTGCAGAGG
    TACGCCGAGG AGGTTGGGAT CTTCTTCACT GCCTCTGGCA TGGATGAGAT GGCAGTTGAA
    TTCCTGCATG AACTGAATGT TCCATTTTTC AAAGTTGGAT CTGGAGACAC TAATAATTTT
    CCTTATCTGG AAAAGACAGC CAAAAAAGGT CGCCCAATGG TGATCTCCAG TGGGATGCAG
    TCAATGGACA CCATGAAGCA AGTTTATCAG ATCGTGAAGC CCCTCAACCC CAACTTCTGC
    TTCTTGCAGT GTACCAGCGC ATACCCGCTC CAGCCTGAGG ACGTCAACCT GCGGGTCATC
    TCGGAATATC AGAAGCTCTT TCCTGACATT CCCATAGGGT ATTCTGGGCA TGAAACAGGC
    ATAGCGATAT CTGTGGCCGC AGTGGCTCTG GGGGCCAAGG TGTTGGAACG TCACATAACT
    TTGGACAAGA CCTGGAAGGG GAGTGACCAC TCGGCCTCGC TGGAGCCTGG AGAACTGGCC
    GAGCTGGTGC GGTCAGTGCG TCTTGTGGAG CGTGCCCTGG GCTCCCCAAC CAAGCAGCTG
    CTGCCCTGTG AGATGGCCTG CAATGAGAAG CTGGGCAAGT CTGTGGTGGC CAAAGTGAAA
    ATTCCGGAAG GCACCATTCT AACAATGGAC ATGCTCACCG TGAAGGTGGG TGAGCCCAAA
    GGCTATCCTC CTGAAGACAT CTTTAATCTA GTGGGCAAGA AGGTCCTGGT CACTGTTGAA
    GAGGATGACA CCATCATGGA AGAATTGGTA GATAATCATG GCAAAAAAAT CAAGTCTTAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu68281
    Clone ID Related Accession (Same CDS sequence) XM_011518788.2
    Accession Version XM_011518788.2 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 705bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-05
    Organism Homo sapiens(human)
    Product sialic acid synthase isoform X2
    Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000009.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011518788.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    ATGTTCCATT TTTCAAAGTT GGATCTGGAG ACACTAATAA TTTTCCTTAT CTGGAAAAGA 
    CAGCCAAAAA AAGGTCGCCC AATGGTGATC TCCAGTGGGA TGCAGTCAAT GGACACCATG
    AAGCAAGTTT ATCAGATCGT GAAGCCCCTC AACCCCAACT TCTGCTTCTT GCAGTGTACC
    AGCGCATACC CGCTCCAGCC TGAGGACGTC AACCTGCGGG TCATCTCGGA ATATCAGAAG
    CTCTTTCCTG ACATTCCCAT AGGGTATTCT GGGCATGAAA CAGGCATAGC GATATCTGTG
    GCCGCAGTGG CTCTGGGGGC CAAGGTGTTG GAACGTCACA TAACTTTGGA CAAGACCTGG
    AAGGGGAGTG ACCACTCGGC CTCGCTGGAG CCTGGAGAAC TGGCCGAGCT GGTGCGGTCA
    GTGCGTCTTG TGGAGCGTGC CCTGGGCTCC CCAACCAAGC AGCTGCTGCC CTGTGAGATG
    GCCTGCAATG AGAAGCTGGG CAAGTCTGTG GTGGCCAAAG TGAAAATTCC GGAAGGCACC
    ATTCTAACAA TGGACATGCT CACCGTGAAG GTGGGTGAGC CCAAAGGCTA TCCTCCTGAA
    GACATCTTTA ATCTAGTGGG CAAGAAGGTC CTGGTCACTG TTGAAGAGGA TGACACCATC
    ATGGAAGAAT TGGTAGATAA TCATGGCAAA AAAATCAAGT CTTAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq XP_011517090.1
    CDS15..719
    Translation

    Target ORF information:

    RefSeq Version XM_011518788.2
    Organism Homo sapiens(human)
    Definition Homo sapiens N-acetylneuraminate synthase (NANS), transcript variant X3, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    XM_011518788.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    ATGTTCCATT TTTCAAAGTT GGATCTGGAG ACACTAATAA TTTTCCTTAT CTGGAAAAGA 
    CAGCCAAAAA AAGGTCGCCC AATGGTGATC TCCAGTGGGA TGCAGTCAAT GGACACCATG
    AAGCAAGTTT ATCAGATCGT GAAGCCCCTC AACCCCAACT TCTGCTTCTT GCAGTGTACC
    AGCGCATACC CGCTCCAGCC TGAGGACGTC AACCTGCGGG TCATCTCGGA ATATCAGAAG
    CTCTTTCCTG ACATTCCCAT AGGGTATTCT GGGCATGAAA CAGGCATAGC GATATCTGTG
    GCCGCAGTGG CTCTGGGGGC CAAGGTGTTG GAACGTCACA TAACTTTGGA CAAGACCTGG
    AAGGGGAGTG ACCACTCGGC CTCGCTGGAG CCTGGAGAAC TGGCCGAGCT GGTGCGGTCA
    GTGCGTCTTG TGGAGCGTGC CCTGGGCTCC CCAACCAAGC AGCTGCTGCC CTGTGAGATG
    GCCTGCAATG AGAAGCTGGG CAAGTCTGTG GTGGCCAAAG TGAAAATTCC GGAAGGCACC
    ATTCTAACAA TGGACATGCT CACCGTGAAG GTGGGTGAGC CCAAAGGCTA TCCTCCTGAA
    GACATCTTTA ATCTAGTGGG CAAGAAGGTC CTGGTCACTG TTGAAGAGGA TGACACCATC
    ATGGAAGAAT TGGTAGATAA TCATGGCAAA AAAATCAAGT CTTAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu98695
    Clone ID Related Accession (Same CDS sequence) XM_017014811.1
    Accession Version XM_017014811.1 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 657bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-05
    Organism Homo sapiens(human)
    Product sialic acid synthase isoform X3
    Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000009.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    ATGGTGTTGG TGCTGGATTA CTCAGGTCGC CCAATGGTGA TCTCCAGTGG GATGCAGTCA 
    ATGGACACCA TGAAGCAAGT TTATCAGATC GTGAAGCCCC TCAACCCCAA CTTCTGCTTC
    TTGCAGTGTA CCAGCGCATA CCCGCTCCAG CCTGAGGACG TCAACCTGCG GGTCATCTCG
    GAATATCAGA AGCTCTTTCC TGACATTCCC ATAGGGTATT CTGGGCATGA AACAGGCATA
    GCGATATCTG TGGCCGCAGT GGCTCTGGGG GCCAAGGTGT TGGAACGTCA CATAACTTTG
    GACAAGACCT GGAAGGGGAG TGACCACTCG GCCTCGCTGG AGCCTGGAGA ACTGGCCGAG
    CTGGTGCGGT CAGTGCGTCT TGTGGAGCGT GCCCTGGGCT CCCCAACCAA GCAGCTGCTG
    CCCTGTGAGA TGGCCTGCAA TGAGAAGCTG GGCAAGTCTG TGGTGGCCAA AGTGAAAATT
    CCGGAAGGCA CCATTCTAAC AATGGACATG CTCACCGTGA AGGTGGGTGA GCCCAAAGGC
    TATCCTCCTG AAGACATCTT TAATCTAGTG GGCAAGAAGG TCCTGGTCAC TGTTGAAGAG
    GATGACACCA TCATGGAAGA ATTGGTAGAT AATCATGGCA AAAAAATCAA GTCTTAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq XP_016870300.1
    CDS257..913
    Translation

    Target ORF information:

    RefSeq Version XM_017014811.1
    Organism Homo sapiens(human)
    Definition Homo sapiens N-acetylneuraminate synthase (NANS), transcript variant X4, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    XM_017014811.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    ATGGTGTTGG TGCTGGATTA CTCAGGTCGC CCAATGGTGA TCTCCAGTGG GATGCAGTCA 
    ATGGACACCA TGAAGCAAGT TTATCAGATC GTGAAGCCCC TCAACCCCAA CTTCTGCTTC
    TTGCAGTGTA CCAGCGCATA CCCGCTCCAG CCTGAGGACG TCAACCTGCG GGTCATCTCG
    GAATATCAGA AGCTCTTTCC TGACATTCCC ATAGGGTATT CTGGGCATGA AACAGGCATA
    GCGATATCTG TGGCCGCAGT GGCTCTGGGG GCCAAGGTGT TGGAACGTCA CATAACTTTG
    GACAAGACCT GGAAGGGGAG TGACCACTCG GCCTCGCTGG AGCCTGGAGA ACTGGCCGAG
    CTGGTGCGGT CAGTGCGTCT TGTGGAGCGT GCCCTGGGCT CCCCAACCAA GCAGCTGCTG
    CCCTGTGAGA TGGCCTGCAA TGAGAAGCTG GGCAAGTCTG TGGTGGCCAA AGTGAAAATT
    CCGGAAGGCA CCATTCTAAC AATGGACATG CTCACCGTGA AGGTGGGTGA GCCCAAAGGC
    TATCCTCCTG AAGACATCTT TAATCTAGTG GGCAAGAAGG TCCTGGTCAC TGTTGAAGAG
    GATGACACCA TCATGGAAGA ATTGGTAGAT AATCATGGCA AAAAAATCAA GTCTTAA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

  • PubMed

    NANS-mediated synthesis of sialic acid is required for brain and skeletal development.
    Nature genetics48(7)777-84(2016 07)
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    Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.
    Mutation research694(1-2)13-9(2010 Dec)
    Flachsbart F,Franke A,Kleindorp R,Caliebe A,Blanch? H,Schreiber S,Nebel A


    Solution structure of the antifreeze-like domain of human sialic acid synthase.
    Protein science : a publication of the Protein Society15(5)1010-6(2006 May)
    Hamada T,Ito Y,Abe T,Hayashi F,G?ntert P,Inoue M,Kigawa T,Terada T,Shirouzu M,Yoshida M,Tanaka A,Sugano S,Yokoyama S,Hirota H


    Cloning, expression, and characterization of sialic acid synthases.
    Biochemical and biophysical research communications338(3)1507-14(2005 Dec)
    Hao J,Balagurumoorthy P,Sarilla S,Sundaramoorthy M


    DNA sequence and analysis of human chromosome 9.
    Nature429(6990)369-74(2004 May)
    Humphray SJ,Oliver K,Hunt AR,Plumb RW,Loveland JE,Howe KL,Andrews TD,Searle S,Hunt SE,Scott CE,Jones MC,Ainscough R,Almeida JP,Ambrose KD,Ashwell RI,Babbage AK,Babbage S,Bagguley CL,Bailey J,Banerjee R,Barker DJ,Barlow KF,Bates K,Beasley H,Beasley O,Bird CP,Bray-Allen S,Brown AJ,Brown JY,Burford D,Burrill W,Burton J,Carder C,Carter NP,Chapman JC,Chen Y,Clarke G,Clark SY,Clee CM,Clegg S,Collier RE,Corby N,Crosier M,Cummings AT,Davies J,Dhami P,Dunn M,Dutta I,Dyer LW,Earthrowl ME,Faulkner L,Fleming CJ,Frankish A,Frankland JA,French L,Fricker DG,Garner P,Garnett J,Ghori J,Gilbert JG,Glison C,Grafham DV,Gribble S,Griffiths C,Griffiths-Jones S,Grocock R,Guy J,Hall RE,Hammond S,Harley JL,Harrison ES,Hart EA,Heath PD,Henderson CD,Hopkins BL,Howard PJ,Howden PJ,Huckle E,Johnson C,Johnson D,Joy AA,Kay M,Keenan S,Kershaw JK,Kimberley AM,King A,Knights A,Laird GK,Langford C,Lawlor S,Leongamornlert DA,Leversha M,Lloyd C,Lloyd DM,Lovell J,Martin S,Mashreghi-Mohammadi M,Matthews L,McLaren S,McLay KE,McMurray A,Milne S,Nickerson T,Nisbett J,Nordsiek G,Pearce AV,Peck AI,Porter KM,Pandian R,Pelan S,Phillimore B,Povey S,Ramsey Y,Rand V,Scharfe M,Sehra HK,Shownkeen R,Sims SK,Skuce CD,Smith M,Steward CA,Swarbreck D,Sycamore N,Tester J,Thorpe A,Tracey A,Tromans A,Thomas DW,Wall M,Wallis JM,West AP,Whitehead SL,Willey DL,Williams SA,Wilming L,Wray PW,Young L,Ashurst JL,Coulson A,Bl?cker H,Durbin R,Sulston JE,Hubbard T,Jackson MJ,Bentley DR,Beck S,Rogers J,Dunham I