LURAP1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	LURAP1
Entrez Gene ID	541468
Full Name	leucine rich adaptor protein 1
Synonyms	C1orf190,LRAP35a,LRP35A
General protein information	Preferred Names leucine rich adaptor protein 1 Names leucine rich adaptor protein 1 NF-kappa-B activator C1orf190 leucine repeat adapter protein 35A leucine repeat adaptor protein 35a
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1p34.1
Disorder MIM:	616129

mRNA and Protein(s)

mRNA	Protein	Name
NM_001013615.3	NP_001013633.1	leucine rich adaptor protein 1
NM_001013615.2	NP_001013633.1	leucine rich adaptor protein 1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	LURAP1	XP_001138722.2
	LURAP1	XP_001107492.1
Homo sapiens (human)	LURAP1	NP_001013633.1
Gallus gallus (chicken)	C1ORF190	XP_422445.2
Bos taurus (cattle)	LURAP1	XP_002686464.2
Canis lupus familiaris (dog)	LURAP1	XP_532593.2
Mus musculus (house mouse)	Lurap1	NP_080823.1
Danio rerio (zebrafish)	zgc:171930	NP_001099178.1
Rattus norvegicus (Norway rat)	Lurap1	NP_001102733.1
Xenopus tropicalis (tropical clawed frog)	lurap1	XP_004914032.1

Gene Ontology
Bibliography

Related articles in PubMed

Widespread macromolecular interaction perturbations in human genetic disorders.
Sahni N, Yi S, Taipale M, Fuxman Bass JI, Coulombe-Huntington J, Yang F, Peng J, Weile J, Karras GI, Wang Y, Kov?cs IA, Kamburov A, Krykbaeva I, Lam MH, Tucker G, Khurana V, Sharma A, Liu YY, Yachie N, Zhong Q, Shen Y, Palagi A, San-Miguel A, Fan C, Balcha D, Dricot A, Jordan DM, Walsh JM, Shah AA, Yang X, Stoyanova AK, Leighton A, Calderwood MA, Jacob Y, Cusick ME, Salehi-Ashtiani K, Whitesell LJ, Sunyaev S, Berger B, Barab?si AL, Charloteaux B, Hill DE, Hao T, Roth FP, Xia Y, Walhout AJM, Lindquist S, Vidal M
Cell161(3)647-660(2015 Apr)

Chromosome 1 open reading frame 190 promotes activation of NF-?B canonical pathway and resistance of dendritic cells to tumor-associated inhibition in vitro.
Jing Z, Yuan X, Zhang J, Huang X, Zhang Z, Liu J, Zhang M, Oyang J, Zhang Y, Zhang Z, Yang R
Journal of immunology (Baltimore, Md. : 1950)185(11)6719-27(2010 Dec)

A tripartite complex containing MRCK modulates lamellar actomyosin retrograde flow.
Tan I, Yong J, Dong JM, Lim L, Leung T
Cell135(1)123-36(2008 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

C1orf190 can activate NF-kappaB, drive production of cytokines, and promote the antigen-presenting function and priming ability of dendritic cells.
Title: Chromosome 1 open reading frame 190 promotes activation of NF-?B canonical pathway and resistance of dendritic cells to tumor-associated inhibition in vitro.

The following LURAP1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LURAP1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu55833	NM_001013615.3 Latest version!	Homo sapiens leucine rich adaptor protein 1 (LURAP1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu55833	NM_001013615.2	Homo sapiens leucine rich adaptor protein 1 (LURAP1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

LURAP1 ( NM_001013615.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001013633.1 Homo sapiens leucine rich adaptor protein 1 (LURAP1), mRNA.

Price & Availability↑

CloneID	OHu55833
Clone ID Related Accession (Same CDS sequence)	NM_001013615.3 , NM_001013615.2
Accession Version	NM_001013615.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 720bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-03
Organism	Homo sapiens(human)
Product	leucine rich adaptor protein 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK057892.1, BX370151.2 and AI077554.1. On Nov 22, 2018 this sequence version replaced NM_001013615.2. ##Evidence-Data-START## Transcript exon combination :: AK057892.1, SRR3476690.510082.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000371980.4/ ENSP00000361048.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGGGGA CCGTGGAGTC CCAGACGCCT GACCTGCGGG ATGTGGAGGG TAAGGTGGGC 
AGGAAGACCC CTGAAGGGCT GCTCCGCGGG CTGCGAGGCG AGTGTGAGCT GGGAACCTCT 
GGCGCCCTGC TGCTCCCAGG GGCGTCTAGC ACCGGCCACG ACTTGGGGGA CAAGATCATG 
GCGCTGAAGA TGGAGCTGGC TTACCTGCGA GCCATCGATG TGAAGATCCT GCAGCAGCTG 
GTGACCTTGA ATGAGGGCAT CGAGGCAGTG CGCTGGCTGT TGGAGGAGCG GGGGACGTTG 
ACCAGTCATT GCAGCAGCCT CACCAGCAGT CAATATAGCC TGACAGGCGG GAGCCCAGGC 
CGCTCAAGGC GAGGCAGCTG GGACAGCCTG CCAGACACCA GCACCACCGA CCGGCTGGAC 
AGTGTCTCTA TTGGCAGCTT CCTGGACACA GTGGCCCCCA GCGAGCTGGA TGAACAGGGC 
CCACCTGGGG CTCCACGTTC CGAGATGGAC TGGGCAAAAG TTATAGCTGG TGGAGAGAGG 
GCCAGGACTG AGGTGGATGT GGCAGCCACC AGGCTAGGGA GCTTGAGAGC TGTGTGGAAG 
CCCCCAGGGG AGAGGCTTCA AGGTGGACCA CCTGAGTCAC CAGAGGATGA GAGTGCCAAG 
CTGGGCTTCG AGGCCCACTG GTTCTGGGAG CAGTGCCAGG ATGATGTGAC CTTCTTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001013633.1
CDS	94..813
Translation	MEGTVESQTPDLRDVEGKVGRKTPEGLLRGLRGECELGTSGALLLPGASSTGHDLGDKIMALKMELAYLRAIDVKILQQLVTLNEGIEAVRWLLEERGTLTSHCSSLTSSQYSLTGGSPGRSRRGSWDSLPDTSTTDRLDSVSIGSFLDTVAPSELDEQGPPGAPRSEMDWAKVIAGGERARTEVDVAATRLGSLRAVWKPPGERLQGGPPESPEDESAKLGFEAHWFWEQCQDDVTFL

Target ORF information:

RefSeq Version	NM_001013615.3
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich adaptor protein 1 (LURAP1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001013615.3

ORF Insert Sequence:

ATGGAGGGGA CCGTGGAGTC CCAGACGCCT GACCTGCGGG ATGTGGAGGG TAAGGTGGGC 
AGGAAGACCC CTGAAGGGCT GCTCCGCGGG CTGCGAGGCG AGTGTGAGCT GGGAACCTCT 
GGCGCCCTGC TGCTCCCAGG GGCGTCTAGC ACCGGCCACG ACTTGGGGGA CAAGATCATG 
GCGCTGAAGA TGGAGCTGGC TTACCTGCGA GCCATCGATG TGAAGATCCT GCAGCAGCTG 
GTGACCTTGA ATGAGGGCAT CGAGGCAGTG CGCTGGCTGT TGGAGGAGCG GGGGACGTTG 
ACCAGTCATT GCAGCAGCCT CACCAGCAGT CAATATAGCC TGACAGGCGG GAGCCCAGGC 
CGCTCAAGGC GAGGCAGCTG GGACAGCCTG CCAGACACCA GCACCACCGA CCGGCTGGAC 
AGTGTCTCTA TTGGCAGCTT CCTGGACACA GTGGCCCCCA GCGAGCTGGA TGAACAGGGC 
CCACCTGGGG CTCCACGTTC CGAGATGGAC TGGGCAAAAG TTATAGCTGG TGGAGAGAGG 
GCCAGGACTG AGGTGGATGT GGCAGCCACC AGGCTAGGGA GCTTGAGAGC TGTGTGGAAG 
CCCCCAGGGG AGAGGCTTCA AGGTGGACCA CCTGAGTCAC CAGAGGATGA GAGTGCCAAG 
CTGGGCTTCG AGGCCCACTG GTTCTGGGAG CAGTGCCAGG ATGATGTGAC CTTCTTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

LURAP1 ( NM_001013615.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001013633.1 Homo sapiens leucine rich adaptor protein 1 (LURAP1), mRNA.

Price & Availability↑

CloneID	OHu55833
Clone ID Related Accession (Same CDS sequence)	NM_001013615.3 , NM_001013615.2
Accession Version	NM_001013615.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 720bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	leucine rich adaptor protein 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK057892.1, BX370151.2 and AI077554.1. On Nov 5, 2008 this sequence version replaced NM_001013615.1. ##Evidence-Data-START## Transcript exon combination :: AK057892.1, SRR1803615.101141.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END##

ATGGAGGGGA CCGTGGAGTC CCAGACGCCT GACCTGCGGG ATGTGGAGGG TAAGGTGGGC 
AGGAAGACCC CTGAAGGGCT GCTCCGCGGG CTGCGAGGCG AGTGTGAGCT GGGAACCTCT 
GGCGCCCTGC TGCTCCCAGG GGCGTCTAGC ACCGGCCACG ACTTGGGGGA CAAGATCATG 
GCGCTGAAGA TGGAGCTGGC TTACCTGCGA GCCATCGATG TGAAGATCCT GCAGCAGCTG 
GTGACCTTGA ATGAGGGCAT CGAGGCAGTG CGCTGGCTGT TGGAGGAGCG GGGGACGTTG 
ACCAGTCATT GCAGCAGCCT CACCAGCAGT CAATATAGCC TGACAGGCGG GAGCCCAGGC 
CGCTCAAGGC GAGGCAGCTG GGACAGCCTG CCAGACACCA GCACCACCGA CCGGCTGGAC 
AGTGTCTCTA TTGGCAGCTT CCTGGACACA GTGGCCCCCA GCGAGCTGGA TGAACAGGGC 
CCACCTGGGG CTCCACGTTC CGAGATGGAC TGGGCAAAAG TTATAGCTGG TGGAGAGAGG 
GCCAGGACTG AGGTGGATGT GGCAGCCACC AGGCTAGGGA GCTTGAGAGC TGTGTGGAAG 
CCCCCAGGGG AGAGGCTTCA AGGTGGACCA CCTGAGTCAC CAGAGGATGA GAGTGCCAAG 
CTGGGCTTCG AGGCCCACTG GTTCTGGGAG CAGTGCCAGG ATGATGTGAC CTTCTTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001013633.1
CDS	94..813
Translation	MEGTVESQTPDLRDVEGKVGRKTPEGLLRGLRGECELGTSGALLLPGASSTGHDLGDKIMALKMELAYLRAIDVKILQQLVTLNEGIEAVRWLLEERGTLTSHCSSLTSSQYSLTGGSPGRSRRGSWDSLPDTSTTDRLDSVSIGSFLDTVAPSELDEQGPPGAPRSEMDWAKVIAGGERARTEVDVAATRLGSLRAVWKPPGERLQGGPPESPEDESAKLGFEAHWFWEQCQDDVTFL

Target ORF information:

RefSeq Version	NM_001013615.2
Organism	Homo sapiens(human)
Definition	Homo sapiens leucine rich adaptor protein 1 (LURAP1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001013615.2

ORF Insert Sequence:

ATGGAGGGGA CCGTGGAGTC CCAGACGCCT GACCTGCGGG ATGTGGAGGG TAAGGTGGGC 
AGGAAGACCC CTGAAGGGCT GCTCCGCGGG CTGCGAGGCG AGTGTGAGCT GGGAACCTCT 
GGCGCCCTGC TGCTCCCAGG GGCGTCTAGC ACCGGCCACG ACTTGGGGGA CAAGATCATG 
GCGCTGAAGA TGGAGCTGGC TTACCTGCGA GCCATCGATG TGAAGATCCT GCAGCAGCTG 
GTGACCTTGA ATGAGGGCAT CGAGGCAGTG CGCTGGCTGT TGGAGGAGCG GGGGACGTTG 
ACCAGTCATT GCAGCAGCCT CACCAGCAGT CAATATAGCC TGACAGGCGG GAGCCCAGGC 
CGCTCAAGGC GAGGCAGCTG GGACAGCCTG CCAGACACCA GCACCACCGA CCGGCTGGAC 
AGTGTCTCTA TTGGCAGCTT CCTGGACACA GTGGCCCCCA GCGAGCTGGA TGAACAGGGC 
CCACCTGGGG CTCCACGTTC CGAGATGGAC TGGGCAAAAG TTATAGCTGG TGGAGAGAGG 
GCCAGGACTG AGGTGGATGT GGCAGCCACC AGGCTAGGGA GCTTGAGAGC TGTGTGGAAG 
CCCCCAGGGG AGAGGCTTCA AGGTGGACCA CCTGAGTCAC CAGAGGATGA GAGTGCCAAG 
CTGGGCTTCG AGGCCCACTG GTTCTGGGAG CAGTGCCAGG ATGATGTGAC CTTCTTGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Widespread macromolecular interaction perturbations in human genetic disorders.
Cell161(3)647-660(2015 Apr)
Sahni N,Yi S,Taipale M,Fuxman Bass JI,Coulombe-Huntington J,Yang F,Peng J,Weile J,Karras GI,Wang Y,Kov?cs IA,Kamburov A,Krykbaeva I,Lam MH,Tucker G,Khurana V,Sharma A,Liu YY,Yachie N,Zhong Q,Shen Y,Palagi A,San-Miguel A,Fan C,Balcha D,Dricot A,Jordan DM,Walsh JM,Shah AA,Yang X,Stoyanova AK,Leighton A,Calderwood MA,Jacob Y,Cusick ME,Salehi-Ashtiani K,Whitesell LJ,Sunyaev S,Berger B,Barab?si AL,Charloteaux B,Hill DE,Hao T,Roth FP,Xia Y,Walhout AJM,Lindquist S,Vidal M

Chromosome 1 open reading frame 190 promotes activation of NF-?B canonical pathway and resistance of dendritic cells to tumor-associated inhibition in vitro.
Journal of immunology (Baltimore, Md. : 1950)185(11)6719-27(2010 Dec)
Jing Z,Yuan X,Zhang J,Huang X,Zhang Z,Liu J,Zhang M,Oyang J,Zhang Y,Zhang Z,Yang R

A tripartite complex containing MRCK modulates lamellar actomyosin retrograde flow.
Cell135(1)123-36(2008 Oct)
Tan I,Yong J,Dong JM,Lim L,Leung T

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LURAP1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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